MCID: HYD003
MIFTS: 28

Hydrarthrosis malady

Summaries for Hydrarthrosis

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33MalaCards
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MalaCards: Hydrarthrosis is related to synovitis and intermittent hydrarthrosis. An important gene associated with Hydrarthrosis is MEFV (Mediterranean fever), and among its related pathways are Passive Transport by Aquaporins and Bile secretion. The compounds hg2+ and mercury have been mentioned in the context of this disorder. Related mouse phenotype hematopoietic system.

Aliases & Classifications for Hydrarthrosis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

hydrarthrosis 8 10 61


External Ids:

Disease Ontology8 DOID:528
ICD9CM27 719.08

Related Diseases for Hydrarthrosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hydrarthrosis:



Diseases related to hydrarthrosis

Clinical Features for Hydrarthrosis

Drugs & Therapeutics for Hydrarthrosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Hydrarthrosis

Drug clinical trials:

Search ClinicalTrials for Hydrarthrosis

Search NIH Clinical Center for Hydrarthrosis

Search CenterWatch for Hydrarthrosis

Genetic Tests for Hydrarthrosis

Anatomical Context for Hydrarthrosis

Animal Models for Hydrarthrosis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Hydrarthrosis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.4AQP9, AQP1, MEFV, TNFRSF1A

Publications for Hydrarthrosis

Sources:
51PubMed
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Articles related to Hydrarthrosis:

(show all 35)
idTitleAuthorsYear
1
Anakinra for a refractory case of intermittent hydrarthrosis with a TRAPS-related gene mutation. (22887853)
2013
2
May some cases of intermittent hydrarthrosis represent an atypical form of calcium pyrophosphate dihydrate crystal deposition disease? Usefulness of mutational analysis of the MEFV gene. (17889261)
2008
3
Association of intermittent hydrarthrosis with MEFV gene mutations. (16802374)
2006
4
Successful therapy with low-dose colchicine in intermittent hydrarthrosis. (12595650)
2003
5
Multicentric reticulohistiocytosis with hydrarthrosis in both knee joints: disease stabilization with synovectomy, and medication with a steroid and low-dose methotrexate. (24383904)
2002
6
Comparison between clinical evaluation and ultrasonography in detecting hydrarthrosis of the knee. (10606382)
1999
7
Analysis of synovial fluid components of hydrarthrosis in long-term hemodialysis patients. (10370156)
1999
8
Intermittent hydrarthrosis. (11273267)
1998
9
Hydrarthrosis of the knee or ankle revealing metaphyseal stress fractures of the tibia. A report of 3 cases. (8523370)
1995
10
Hyaluronan, cartilage destruction and hydrarthrosis in traumatic arthritis. (11548232)
1994
11
The treatment of idiopathic and secondary hydrarthrosis of the knee by intra-articular Rifamycin SV. (2098221)
1990
12
Participation of synovial mast cells in intermittent hydrarthrosis. (2467680)
1989
13
Treatment of hydrarthrosis of the knee with manual manipulation and herbs. (3246884)
1988
14
Calcium pyrophosphate crystals in intermittent hydrarthrosis. (3029370)
1986
15
LE cells in intermittent hydrarthrosis. (6157396)
1980
16
Periodic synoviosis (intermittent hydrarthrosis) with observations and studies on a patient. (4464498)
1974
17
Tarsal hydrarthrosis in the horse: response to intra-articular injection of synthetic steroids. (5815590)
1969
18
Evaluation of intra-articular injection of synthetic steroids in tarsal hydrarthrosis in cattle. (5691642)
1968
19
Tarsal hydrarthrosis (bog spavin) in the horse: blood, serum, and synovial fluid findings. (5688981)
1968
20
Intra-articular injection of 6 alpha-methyl, 17 alpha-hydroxyprogesterone acetate in tarsal hydrarthrosis (bog spavin) in the horse. (5624181)
1967
21
Therapeutic management of tarsal hydrarthrosis (bog spavin) in the horse by intra-articular injection of prednisolone. (6068578)
1967
22
Characteristics of blood, serum, and synovial effusions in cattle with tarsal hydrarthrosis. (6069486)
1967
23
Acute Cervical Hydrarthrosis. (19790510)
1964
24
SYPHILITIC HYDRARTHROSIS. (14075738)
1963
25
Intermittent hydrarthrosis; periodic benign synovitis. (13567199)
1958
26
Intermittent hydrarthrosis. (13383213)
1957
27
Periodic benign synovitis; idiopathic intermittent hydrarthrosis. (13367081)
1956
28
Hodgkin's disease presenting as hydrarthrosis of knee. (14378634)
1955
29
Intermittent hydrarthrosis. (14372871)
1955
30
Intermittent hydrarthrosis. (14933539)
1952
31
Intermittent hydrarthrosis; two cases. (15390577)
1949
32
The roentgenographic appearance of temporomandibular hydrarthrosis. (21018447)
1946
33
Idiopathic Hydrarthrosis. (19988486)
1932
34
Intermittent Hydrarthrosis: (Hydrops Intermittens Articulorum). (21433466)
1930
35
Chronic Hydrarthrosis. (19976537)
1913

Genetic Variations for Hydrarthrosis

Expression for genes affiliated with Hydrarthrosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hydrarthrosis

Search GEO for disease gene expression data for Hydrarthrosis.

Pathways for genes affiliated with Hydrarthrosis

Sources:
54Reactome, 30KEGG, 52QIAGEN
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Pathways related to Hydrarthrosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4AQP9, AQP1
29.4AQP9, AQP1
3
Hide members
8.8AQP9, AQP1, TNFRSF1A

Compounds for genes affiliated with Hydrarthrosis

Sources:
29IUPHAR, 45Novoseek, 60Tocris Bioscience, 2BitterDB, 11DrugBank, 24HMDB
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Compounds related to Hydrarthrosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1hg2+299.6AQP9, AQP1
2mercury459.5AQP9, AQP1
3mevalonate459.5MEFV, TNFRSF1A
4colchicine60 45 2 29 1113.4TNFRSF1A, MEFV
5endotoxin459.4MEFV, TNFRSF1A
6mannitol45 1110.3AQP9, AQP1
7urea45 11 2411.1AQP9, AQP1

GO Terms for genes affiliated with Hydrarthrosis

Sources:
16Gene Ontology
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Cellular components related to Hydrarthrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basolateral plasma membraneGO:0163239.4AQP9, AQP1

Biological processes related to Hydrarthrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1glycerol transportGO:0157939.5AQP9, AQP1
2water transportGO:0068339.5AQP9, AQP1
3cellular response to cAMPGO:0713209.4AQP9, AQP1
4positive regulation of angiogenesisGO:0457669.3AQP1, TNFRSF1A
5negative regulation of inflammatory responseGO:0507289.3TNFRSF1A, MEFV
6cellular response to mechanical stimulusGO:0712609.0AQP1, TNFRSF1A

Molecular functions related to Hydrarthrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1water channel activityGO:0152509.4AQP9, AQP1
2water transmembrane transporter activityGO:0053729.1AQP9, AQP1

Products for genes affiliated with Hydrarthrosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hydrarthrosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet