MCID: HYD006
MIFTS: 58

Hydrocephalus malady

Categories: Genetic diseases, Rare diseases, Neuronal diseases, Gastrointestinal diseases, Fetal diseases

Aliases & Classifications for Hydrocephalus

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Aliases & Descriptions for Hydrocephalus:

Name: Hydrocephalus 32 10 45 46 47 12 36 24 35 65
Hydrocephalus, Nonsyndromic, Autosomal Recessive 1 65
Hydrocephalus, Nonsyndromic, Autosomal Recessive 10
Hydrocephalus Adverse Event 65
 
Hydrocephalus, X-Linked 10
Ventriculomegaly 45
Hydrocephaly 45

Classifications:



External Ids:

Disease Ontology10 DOID:10908
ICD1027 G91, G91.9
MeSH36 D006849
NCIt42 C3111
UMLS65 C0020255, C1963137, C3887608

Summaries for Hydrocephalus

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NINDS:46 Hydrocephalus is a condition in which the primary characteristic is excessive accumulation of cerebrospinal fluid (CSF) -- the clear fluid that surrounds the brain and spinal cord. This excessive accumulation results in an abnormal dilation of the spaces in the brain called ventricles. This dilation causes potentially harmful pressure on the tissues of the brain. Hydrocephalus may be congenital or acquired. Congenital hydrocephalus is present at birth and may be caused by genetic abnormalities or Acquired hydrocephalus develops at the time of birth or at some point afterward and can affect individuals of all ages. For example, h Symptoms of hydrocephalus vary with age, disease progression, and individual differences in tolerance to CSF. In infancy, the most obvious indication of hydrocephalus is often the rapid increase in head circumference or an unusually large head size. In older children and adults, symptoms may include headache followed by vomiting, nausea, papilledema (swelling of the optic disk, which is part of the optic nerve), downward deviation of the eyes (called "sunsetting"), problems with balance, poor coordination, gait disturbance, urinary incontinence, slowing or loss of development (in children), lethargy, drowsiness, irritability, or other changes in personality or cognition, including memory loss. Hydrocephalus is diagnosed through clinical neurological evaluation and by using cranial imaging techniques such as ultrasonography, computer tomography (CT), magnetic resonance imaging (MRI), or pressure-monitoring techniques.

MalaCards based summary: Hydrocephalus, also known as hydrocephalus, nonsyndromic, autosomal recessive 1, is related to astrocytoma and normal pressure hydrocephalus. An important gene associated with Hydrocephalus is L1CAM (L1 Cell Adhesion Molecule), and among its related pathways are Transcriptional Regulatory Network in Embryonic Stem Cell and CTLA4 Signaling. Affiliated tissues include brain, spinal cord and lung, and related mouse phenotypes are pigmentation and tumorigenesis.

Disease Ontology:10 A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.

NIH Rare Diseases:45 Hydrocephalus is a condition characterized by excessive accumulation of fluid in the brain. although it was once known as "water on the brain," the "water" is actually cerebrospinal fluid (csf) - clear fluid that surrounds the brain and spinal cord. excess csf builds up when it cannot drain from the brain due to a blockage in a passage through which the fluid normally flows.  this excess fluid causes an abnormal widening of spaces in the brain called ventricles; this can create harmful pressure on brain tissue. symptoms vary with age, disease progression, and individual differences in tolerance to the condition. hydrocephalus may be congenital (present at birth) or acquired. the causes are not fully understood; it may result from inherited genetic abnormalities or developmental disorders; complications of premature birth; diseases such as meningitis; tumors; traumatic head injury; or other causes. it is most often treated by surgically inserting a shunt system. last updated: 8/22/2011

MedlinePlus:35 Hydrocephalus is the buildup of too much cerebrospinal fluid in the brain. normally, this fluid cushions your brain. when you have too much, though, it puts harmful pressure on your brain. hydrocephalus can be congenital, or present at birth. causes include genetic problems and problems with how the fetus develops. an unusually large head is the main sign of congenital hydrocephalus. hydrocephalus can also happen after birth. this is called acquired hydrocephalus. it can occur at any age. causes can include head injuries, strokes, infections, tumors, and bleeding in the brain. symptoms include headache vomiting and nausea blurry vision balance problems bladder control problems thinking and memory problems hydrocephalus can permanently damage the brain, causing problems with physical and mental development. if untreated, it is usually fatal. with treatment, many people lead normal lives with few limitations. treatment usually involves surgery to insert a shunt. a shunt is a flexible but sturdy plastic tube. the shunt moves the cerebrospinal fluid to another area of the body where it can be absorbed. medicine and rehabilitation therapy can also help. nih: national institute of neurological disorders and stroke

Wikipedia:68 Hydrocephalus (from Greek hydro-, meaning \"water\", and kephalos, meaning \"head\") is a medical... more...

Related Diseases for Hydrocephalus

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Diseases in the Hydrocephalus family:

Hydrocephalus, Autosomal Dominant Hydrocephalus, Nonsyndromic, Autosomal Recessive 2
Hydrocephalus, Nonsyndromic, Autosomal Recessive Hydrocephalus Due to Aqueductal Stenosis
Hydrocephalus Autosomal Recessive Hydrocephalus Due to Congenital Stenosis of Aqueduct of Sylvius
Nonsyndromic Hydrocephalus, Ccdc88c-Related Nonsyndromic Hydrocephalus, Mpdz-Related
Congenital Hydrocephalus

Diseases related to Hydrocephalus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 1110)
idRelated DiseaseScoreTop Affiliating Genes
1astrocytoma29.4AKT3, NES, PTEN, TP53
2normal pressure hydrocephalus12.7
3ventriculomegaly with cystic kidney disease12.6
4hydrocephalus due to aqueductal stenosis12.5
5proliferative vasculopathy and hydraencephaly-hydrocephaly syndrome12.5
6communicating hydrocephalus12.5
7megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 112.4
8chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia12.4
9hydrocephalus, nonsyndromic, autosomal recessive 212.4
10hydrocephalus, nonsyndromic, autosomal recessive12.4
11megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 212.4
12obstructive hydrocephalus12.4
13megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 312.4
14hydrocephalus with stenosis of the aqueduct of sylvius12.4
15hydrocephalus due to congenital stenosis of aqueduct of sylvius12.3
16congenital non-communicating hydrocephalus12.3
17congenital communicating hydrocephalus12.3
18megalencephaly, polymicrogyria, and hydrocephalus syndrome12.3
19congenital hydrocephalus12.3
20isolated dandy-walker malformation without hydrocephalus12.2
21isolated dandy-walker malformation with hydrocephalus12.2
22bor-duane hydrocephalus contiguous gene syndrome12.2
23hydrocephalus obesity hypogonadism12.2
24hydrocephalus, costovertebral dysplasia, and sprengel anomaly12.2
25thoracic dysplasia hydrocephalus syndrome12.2
26nonsyndromic hydrocephalus, mpdz-related12.2
27hydrocephalus, autosomal dominant12.2
28dandy-walker malformation with sagittal craniosynostosis and hydrocephalus12.2
29megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome, somatic12.2
30nonsyndromic hydrocephalus, ccdc88c-related12.2
31vacterl with hydrocephalus, fancb-related12.2
32amelia cleft lip palate hydrocephalus iris coloboma12.1
33hydrocephalus autosomal recessive12.1
34hydrocephalus craniosynostosis bifid nose12.1
35hydrocephalus growth retardation skeletal anomalies12.1
36hydrocephalus skeletal anomalies12.1
37tibial aplasia ectrodactyly hydrocephalus12.1
38x-linked hydrocephalus with stenosis of the aqueduct of sylvius12.1
39craniosynostosis-dandy-walker malformation-hydrocephalus syndrome12.1
40craniosynostosis-hydrocephalus-arnold-chiari malformation type i-radioulnar synostosis syndrome12.1
41vacterl with hydrocephalus12.1
42megalencephaly-polymicrogyria-postaxial polydactyly-hydrocephalus syndrome12.1
43masa syndrome11.9
44dandy-walker syndrome11.8
45vacterl association, x-linked11.7
46vater association with macrocephaly and ventriculomegaly11.7
47hec syndrome11.7
48walker-warburg syndrome11.7
49cole-carpenter syndrome11.6
50cole-carpenter syndrome 111.5

Graphical network of the top 20 diseases related to Hydrocephalus:



Diseases related to hydrocephalus

Symptoms for Hydrocephalus

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Drugs & Therapeutics for Hydrocephalus

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Drugs for Hydrocephalus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 88)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CitalopramapprovedPhase 449459729-33-82771
Synonyms:
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
1,3-dihydro[3,4]benzofuran-5-carbonitrile
1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
59729-33-8
AB00513896
AC-12214
AC1L1EFH
AE-641/00603021
Akarin
BPBio1_000929
BRD-A47598013-004-02-0
BSPBio_000843
Bonitrile
C07572
C20H21FN2O
CHEBI:3723
CHEMBL549
CID2771
CPD000465669
Celapram
Celexa
Celius
Ciazil
Cilift
Cipram
Cipramil
Ciprapine
Citabax
Citadur
Citadur (TN)
Citalec
Citalopram
Citalopram (USP/INN)
Citalopram Hydrobromide
Citalopram [Celexa]
Citalopram [INN:BAN]
Citalopram hydrobromide
Citalopramum
Citalopramum [INN-Latin]
 
Citol
Citopam
Citox
Citrol
Cytalopram
D07704
DB00215
Dalsan
EINECS 261-891-1
Elopram
HMS2090O09
HMS2093A14
Humorup
I01-0382
InChI=1/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
L001223
LS-84327
Lopac0_000258
Lu 10-171
Lu-10-171
MolPort-003-666-794
NCGC00015267-07
NCGC00025160-02
Nitalapram
Oropram
Perrigo Citalopram
Pramcit
Prestwick3_000692
Recital
SAM002589960
ST069372
STL058639
Seropram
Talam
Talohexal
Temperax
UNII-0DHU5B8D6V
Vodelax
Zentius
Zetalo
[3H]Citalopram
citalopram
2
SerotoninPhase 4314750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
3Serotonin AgentsPhase 42668
4Neurotransmitter Uptake InhibitorsPhase 42857
5Cholinergic AgentsPhase 43243
6Serotonin Uptake InhibitorsPhase 41369
7Neurotransmitter AgentsPhase 4, Phase 314795
8Cholinergic AntagonistsPhase 41423
9Muscarinic AntagonistsPhase 4961
10
RifampicinapprovedPhase 330313292-46-15458213, 5381226
Synonyms:
1-b]furan-21-yl acetate
13292-46-1
3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin sv
3-(4-Methylpiperazinyliminomethyl)-rifamycin SV
3-(4-Methylpiperazinyliminomethyl)rifamycin SV
3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV
3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV
3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin
46713_FLUKA
46713_RIEDEL
62534-43-4
8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
8-(4-Methylpiperazinyliminomethyl) rifamycin SV
8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin
8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv
8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv
83907_FLUKA
83907_SIGMA
8CI)
AZT + Rifampin
Abrifam
Archidyn
Arficin
Arzide
BA-41166E
BIDD:PXR0014
BPBio1_000561
BSPBio_000509
Ba 41166
Ba 41166/E
Benemicin
Benemycin
Bio-0621
C06688
C43H58N4O12
CAS-13292-46-1
CCRIS 551
CHEBI:28077
CHEBI:455936
CHEMBL180
CID5381226
CID5388984
CID5458213
CID5702112
CID6604339
CID6708473
CID6842115
CID6912767
CID6913622
CPD001906767
D00211
DB01045
DRG-0109
Dione 21-acetate
Dipicin
DivK1c_000550
Doloresum
EINECS 236-312-0
Eremfat
Famcin
Fenampicin
HMS1569J11
HMS1920P08
HMS2089F12
HMS2092G09
HMS501L12
HSDB 3181
KBio1_000550
KBio2_000919
KBio2_003487
KBio2_006055
KBio3_003018
KBioGR_001780
KBioSS_000919
L-5103
L-5103 Lepetit
LS-7689
MLS000028552
MLS001148237
MLS001333745
MolPort-000-767-051
MolPort-002-513-586
MolPort-003-666-281
MolPort-006-395-891
NCGC00016699-01
NCGC00017365-01
NCGC00018178-01
NCGC00022678-03
NCGC00022678-04
NCGC00022678-05
NCGC00160500-01
 
NCI60_000309
NINDS_000550
NSC 113926
NSC-113926
NSC113926
Piperine & Rifampicin
Prestwick0_000525
Prestwick1_000525
Prestwick2_000525
Prestwick3_000525
Prestwick_833
R-Cin
R/AMP
R0079
R3501_SIAL
R3501_SIGMA
R5777_SIGMA
R7382_SIGMA
RAMP
RFP
RMP
Ramp
Reserpine & Rifampicin
Rf
Rfamipicin
Rifa
Rifadin
Rifadin (TN)
Rifadin I.V
Rifadin I.V.
Rifadin IV
Rifadin Iv
Rifadin, Rimactane, Rifampicin, Rifampin
Rifadine
Rifagen
Rifaldazin
Rifaldazine
Rifaldin
Rifam
Rifamicin AMP
Rifamor
Rifampicin
Rifampicin & EEP
Rifampicin & Propolis
Rifampicin (JP15/INN)
Rifampicin SV
Rifampicin [INN:BAN:JAN]
Rifampicin sodium
Rifampicina
Rifampicina [INN-Spanish]
Rifampicine
Rifampicine [French]
Rifampicinum
Rifampicinum [INN-Latin]
Rifampin
Rifampin (USP)
Rifampin [USAN]
Rifamsolin
Rifamycin
Rifamycin AMP
Rifamycin Amp
Rifaprodin
Rifcin
Rifinah
Rifobac
Rifoldin
Rifoldine
Riforal
Rimactan
Rimactane
Rimactane (TN)
Rimactazid
Rimactin
Rimactizid
Rimazid
Rimycin
Rofact
S1764_Selleck
SAM002264646
SMR000058322
SMR000653525
SPBio_002430
SPECTRUM1500529
STK080143
Sinerdol
Spectrum3_001837
Spectrum4_001250
Spectrum5_002018
Spectrum_000439
TNP00313
Tubocin
UNII-VJT6J7R4TR
WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1
nchembio884-comp4
rifampin
11
ClindamycinapprovedPhase 315718323-44-929029
Synonyms:
13441-63-9
16669-21-9
18323-44-9
21462-39-5 (mono-hydrochloride)
24620-78-8
24696-19-3
58207-19-5
7(S)-Chloro-7-deoxylincomycin
7-CDL
7-Chloro-7-deoxylincomycin
7-Chlorolincomycin
7-Deoxy-7(S)-chlorolincomycin
AC1L1EGQ
AC1L1GLA
AC1L9JV8
AC1MHD7N
AC1MHE1M
AC1MHUOE
AC1MHX4G
AC1NWAKO
AC1O7ENS
AC1O7GED
AC1OFCIP
AC1OFCIV
AC1OFCJ1
AC1OFCJ7
AC1OIBYJ
AC1OIBYL
AC1OIBYN
AC1Q2V4O
Antirobe
BIDD:GT0418
BPBio1_000236
BRD-A23034328-003-03-4
BSPBio_000214
BSPBio_002049
C06914
C18H33ClN2O5S
CAS-21462-39-5
CHEBI:3745
CHEMBL187
CID2786
CID29029
CID3000512
CID3001928
CID3032758
CID3034218
CID446598
CID5702026
CID6602476
CID6604361
CID7048642
CID7048644
CID7048646
CID7048648
CID7276014
CID7276016
CID7276018
CID9812677
CLDM
CLINDA & IL-12
CLY
Chlolincocin
Chlorlincocin
Chlorodeoxylincomycin
Chlorolincomycin
Cleocin
Cleocin (TN)
Cleocin (tn)
Cleocin HCl
Cleocin Hydrochloride
Cleocin T Gel
Cleocin T Lotion
Cleocin T Topical Solution
 
Clinda-derm
ClindaDerm
Clindagel
Clindamax
Clindamicina
Clindamicina [INN-Spanish]
Clindamycin
Clindamycin & Interleukin 12
Clindamycin & VRC3375
Clindamycin (USAN/INN)
Clindamycin Phosphate
Clindamycin [USAN:BAN:INN]
Clindamycine
Clindamycine [French]
Clindamycine [INN-French]
Clindamycinum
Clindamycinum [INN-Latin]
Clindesse
Clinimycin
D00277
DB01190
Dalacin C
Dalacin C Flavored Granules
Dalacin C Phosphate
Dalacin T Topical Solution
Dalacine
DivK1c_000464
EINECS 242-209-1
Evoclin
HMS2089A05
HMS2089N16
HSDB 3037
I06-0826
IDI1_000464
KBio1_000464
KBio2_000638
KBio2_003206
KBio2_005774
KBio3_001269
KBioGR_000844
KBioSS_000638
Klimicin
Klindan 300
LS-187128
LS-98131
MLS001183714
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside
MolPort-002-323-206
MolPort-002-964-479
NCGC00016752-01
NCGC00178843-01
NCGC00179636-01
NINDS_000464
Prestwick0_000137
Prestwick1_000137
Prestwick2_000137
Prestwick3_000137
ResiDerm A
SMP2_000295
SMR000677917
SPBio_000670
SPBio_002153
STK177246
STOCK1N-31150
Sobelin
Spectrum2_000885
Spectrum3_000355
Spectrum4_000292
Spectrum5_001525
Spectrum_000158
U 21251
U-21,251
U-21251
UNII-3U02EL437C
Zindaclin
clindamycin
12
Midazolamapproved, illicitPhase 363559467-70-84192
Synonyms:
4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate
59467-70-8
8-Chlor-6-(2-fluorphenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepin
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride
8-Chloro-6-(O-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]-benzodiazepine
8-Chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine
AC-18749
AC1L1HMA
BIDD:GT0647
BRN 0625572
Buccolam
C07524
C18H13ClFN3
CHEMBL655
CID4192
D00550
DB00683
DEA No. 2884
Dazolam
Dea No. 2884
Dormicum
 
Dormicum (TN)
EINECS 261-774-5
LS-77780
Midanium
Midazolam
Midazolam (JAN/INN)
Midazolam Base
Midazolam Hcl
Midazolam Hydrochloride
Midazolam [INN:BAN:JAN]
Midazolamum
Midazolamum [INN-Latin]
Midosed
MolPort-003-849-219
NCGC00168254-01
Ro 21-3981
TL8003787
UC429_SIGMA
UNII-R60L0SM5BC
Versed
ZINC00001732
midazolam
nchembio747-comp32
13
AcetazolamideapprovedPhase 36759-66-51986
Synonyms:
1424-27-7 (mono-hydrochloride salt)
1yda
1ydb
1ydd
1zsb
2-acetylamino-1,3,4-Thiadiazole-5-sulfonamide
2h4n
3czv
4-Diamox
5-ACETAMIDO-1,3,4-thiadiazole-2-sulfonamide
5-acetylamino-1,3,4-Thiadiazole-2-sulfonamide
5661-25-6
59-66-5
8017-69-4
A 6011
A6011_SIAL
A6011_SIGMA
AB00051906
AC-12779
AC1L1CO5
AI3-52458
AKOS000715163
Acetadiazol
Acetamidothiadiazolesulfonamide
Acetamox
Acetazolam
Acetazolamid
Acetazolamida
Acetazolamida [INN-Spanish]
Acetazolamide
Acetazolamide (AAZ)
Acetazolamide (JP15/USP/INN)
Acetazolamide Apotex Brand
Acetazolamide Chiesi Brand
Acetazolamide Dioptic Brand
Acetazolamide Grin Brand
Acetazolamide ICN Brand
Acetazolamide Jumer Brand
Acetazolamide Llorens Brand
Acetazolamide Medphano Brand
Acetazolamide Novopharm Brand
Acetazolamide Orion Brand
Acetazolamide Sodium
Acetazolamide Sodium, (Sterile)
Acetazolamide Wassermann Brand
Acetazolamide [INN:BAN:JAN]
Acetazolamide, Monosodium Salt
Acetazolamidum
Acetazolamidum [INN-Latin]
Acetazolamine
Acetazoleamide
Acetozalamide
Acétazolamide
Ak Zol
Ak-Zol
AkZol
Apo Acetazolamide
Apo-Acetazolamide
ApoAcetazolamide
Apotex Brand of Acetazolamide
Atenezol
Avva
BAS 01585728
BIDD:GT0643
BPBio1_000007
BSPBio_000005
BSPBio_001788
C06805
C4H6N4O3S2
CAS-59-66-5
CCRIS 5811
CHEBI:27690
CHEMBL20
CID1986
CPD0-1626
CPD000058394
Carbonic Anhydrase Inhibitor 6063
Carbonic Anhydrase Inhibitor No. 6063
Carbonic anhydrase inhibitor 6063
Chiesi Brand of Acetazolamide
Ciba Vision Brand of Acetazolamide
Cidamex
D000086
D00218
DB00819
Dazamide
Defiltran
Dehydratin
Diacarb
Diakarb
Diamox
Diamox (TN)
Diamox Sequels
Didoc
 
Diluran
Dioptic Brand of Acetazolamide
Diuramid
Diuramide
Diureticum-Holzinger
Diureticum-holzinger
Diuriwas
Diutazol
DivK1c_000017
Donmox
Duiramid
EINECS 200-440-5
EU-0100039
Edemox
Eumicton
Fonurit
Glauconox
Glaumox
Glaupax
Glupax
Grin Brand of Acetazolamide
HMS1568A07
HMS1920A05
HMS2091G05
HMS500A19
HSDB 3002
Huma Zolamide
Huma-Zolamide
HumaZolamide
I09-0425
ICN Brand of Acetazolamide
IDI1_000017
Jumer Brand of Acetazolamide
KBio1_000017
KBio2_000358
KBio2_002926
KBio2_005494
KBio3_001288
KBioGR_000558
KBioSS_000358
LS-10227
Llorens Brand of Acetazolamide
Lopac-A-6011
Lopac0_000039
MLS000028435
MLS001148438
Medphano Brand of Acetazolamide
MolPort-001-783-578
Monosodium Salt Acetazolamide
N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
N-[5-(Aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamide
NCGC00015074-01
NCGC00015074-02
NCGC00015074-03
NCGC00015074-06
NCGC00015074-11
NCGC00023455-03
NCGC00023455-04
NCGC00023455-05
NCGC00023455-06
NCGC00023455-07
NINDS_000017
NSC 145177
NSC145177
Natrionex
Nephramid
Nephramide
Novopharm Brand of Acetazolamide
Orion Brand of Acetazolamide
Phonurit
Prestwick0_000003
Prestwick1_000003
Prestwick2_000003
Prestwick3_000003
Prestwick_4
SAM002554883
SBB056640
SK-acetazolamide
SMR000058394
SPBio_000004
SPBio_001926
SPECTRUM1500102
Sk-Acetazolamide
Spectrum2_000082
Spectrum3_000284
Spectrum4_000139
Spectrum5_000738
Spectrum_000018
Storz Brand of Acetazolamide Preparation
Storzolamide
UNII-O3FX965V0I
Vetamox
WLN: T5NN DSJ CSZW EMV1
Wassermann Brand of Acetazolamide
Wyeth Brand of Acetazolamide Preparation
acetazolamide
14
Epoetin alfaapprovedPhase 3626113427-24-0
Synonyms:
Epogen
 
Erythropoietin precursor
Procrit
15
Tranexamic AcidapprovedPhase 2, Phase 32261197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
KBioSS_001871
 
LS-56611
LS-56612
LT00159441
Lysteda
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic Acid
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
16
IsofluraneapprovedPhase 38726675-46-73763
Synonyms:
1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether
1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether
2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane
26675-46-7
AC-154802
AC1L1GNN
AErrane (Veterinary)
Aerrane
BRN 1852087
C07518
CCRIS 3043
CHEBI:6015
CHEMBL1256
CID3763
Compound 469
D00545
D007530
DB00753
EINECS 247-897-7
Ethane
Ether, 1-chloro-2,2,2-trifluoroethyl difluoromethyl
 
Forane
Forane (TN)
Forene
I14-1303
IsoFlo
Isoflurane
Isoflurane (JP15/USP/INN)
Isoflurane [Anaesthetics, volatile]
Isoflurane [USAN:BAN:INN:JAN]
Isoflurane [USAN:INN:BAN:JAN]
Isoflurane [Usan:Ban:Inn:Jan]
Isoflurano
Isoflurano [INN-Spanish]
Isofluranum
Isofluranum [INN-Latin]
Jsp005223
LS-7462
MolPort-000-153-606
NCGC00181037-01
R-E 235dal
ST51041445
Terrell
UNII-CYS9AKD70P
isoflurane
17
RemifentanilapprovedPhase 3409132875-61-760815
Synonyms:
1-Piperidinepropanoic acid, 4-(methoxy-carbonyl)-4-((1-oxopropyl)phenylamino)-, methyl ester
132539-07-2 (mono-hydrochloride)
132875-61-7
3-(4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic acid methyl ester
4-carboxy-4-(n-phenylpropionamido)-1-piperidinepropionic acid dimethyl ester
AC1L1TZ8
AC1Q5ZGR
BIDD:GT0029
C08021
CHEBI:8802
CHEMBL1005
CID60815
D08473
DB00899
 
DEA No. 9739
GI 87084B
GI 87084X
GI87084B
L001266
LS-115982
MolPort-004-286-006
REMIFENTANIL
Remifentanil (INN)
Remifentanil [INN:BAN]
Remifentanyl
UNII-P10582JYYK
Ultiva
Ultiva (TN)
methyl 1-(3-methoxy-3-oxopropyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
18
DexmedetomidineapprovedPhase 3470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
19
Caffeineapproved, NutraceuticalPhase 333958-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert
Alert-Pep
Alert-pep
Allertness Aid
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
Awake
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine
Caffeine (USP)
Caffeine (natural)
Caffeine Citrate
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine citrate
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffine
Cafipel
Caféine
Circle K Nosnooze
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
Conrx Alert
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
Diurex Ultra
Diurex WaterCaps
DivK1c_000730
Drowz Away Maximum strength
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Equaline Stay Awake
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Good Neighbor Pharmacy Stay Awake
Good Sense Stay Awake
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Health Mart Stay Awake
Healthy Accents Stay Awake
Hycomine
Hycomine Compound
I14-4386
IDI1_000730
 
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Leader Alertness Aid
Lil Drug Store Nosnooze
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Caffeine
Maximum Strength Snapback Stimulant Powders
Maximum Strength Stay Awake
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Nano Ppc
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Pep-back Peak Performance
Pep-back Ultra
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Smart Sense Stay Awake
Sohmed Alertness Aid
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stay Alert Aid
Stay Awake
Stay Awake Maximum Strength
Stay Awake Maximum strength
Stim
Sunmark Stay Awake
Synalgos-Dc
TNP00310
Teina
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Topcare Stay Awake maximum strength
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
20Tranquilizing AgentsPhase 33597
21Psychotropic DrugsPhase 35501
22Caffeine citratePhase 317
23Purinergic P1 Receptor AntagonistsPhase 3262
24Central Nervous System StimulantsPhase 31721
25Phosphodiesterase InhibitorsPhase 31062
26Central Nervous System DepressantsPhase 310016
27Clindamycin palmitatePhase 3157
28Pharmaceutical SolutionsPhase 3, Phase 27004
29Antitubercular AgentsPhase 31061
30Anti-Infective AgentsPhase 317220
31Anti-Bacterial AgentsPhase 39140
32Antibiotics, AntitubercularPhase 35971
33AnestheticsPhase 3, Phase 27385
34Clindamycin phosphatePhase 3157
35Anesthetics, GeneralPhase 32274
36GABA ModulatorsPhase 3657
37Hypnotics and SedativesPhase 32032
38Anti-Anxiety AgentsPhase 31529
39Anesthetics, IntravenousPhase 31943
40HemostaticsPhase 2, Phase 31082
41Immunoglobulin GPhase 3146
42ImmunoglobulinsPhase 34477
43AntibodiesPhase 34477
44HematinicsPhase 31121
45CoagulantsPhase 2, Phase 31042
46Antifibrinolytic AgentsPhase 2, Phase 3346
47AnticonvulsantsPhase 32249
48Contraceptives, OralPhase 33734
49Carbonic Anhydrase InhibitorsPhase 3153
50Anti-Infective Agents, LocalPhase 2, Phase 3984

Interventional clinical trials:

(show top 50)    (show all 133)
idNameStatusNCT IDPhase
1Normal Pressure Hydrocephalus (NPH) RegistryCompletedNCT00233701Phase 4
2A Registry for Comparing Catheter-Related Infection Rates Among Various Shunt Systems in the Treatment of HydrocephalusCompletedNCT00280904Phase 4
3ShuntCheck Versus Radionuclide in Evaluating Shunt Function in Symptomatic NPH PatientsCompletedNCT01323764Phase 4
4NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care UnitCompletedNCT01685476Phase 4
5Efficacy and Safety of Selective Serotonin Reuptake Inhibitor (SSRI) in Overactive Bladder PatientsCompletedNCT00902421Phase 4
6NIMIP: Non Invasive Measurement of the Intracranial PressureRecruitingNCT01685450Phase 4
7ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes StudyRecruitingNCT01881711Phase 4
8Effect of Intrathoracic Pressure Regulation on Traumatic Brain InjuryTerminatedNCT01824589Phase 4
9ShuntCheck Accuracy in Detecting Shunt Obstruction Normal Pressure Hydrocephalus (NPH) PatientsWithdrawnNCT00793416Phase 4
10Multi-Center Study of ShuntCheckWithdrawnNCT00788385Phase 4
11A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular HemorrhageCompletedNCT01041950Phase 2, Phase 3
12PET Imaging of Brain Amyloid in Normal Pressure HydrocephalusCompletedNCT01053312Phase 3
13A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System.CompletedNCT00196196Phase 3
14Premature Infants in Need of Transfusion (PINT)CompletedNCT00182390Phase 3
15Impact of Ventricular Catheter Used With Antimicrobial Agents on Patients With a Ventricular CatheterCompletedNCT00286104Phase 3
16Intraoral 30% Glucose Effect In NewbornsCompletedNCT02325583Phase 3
17High Versus Low Dose of Caffeine for Apnea of PrematurityCompletedNCT02103777Phase 3
18Neurocognitive Outcomes and Changes in Brain and CSF Volume After Treatment of PIH in Ugandan Infants by Shunting vs ETV/CPCRecruitingNCT01936272Phase 3
19Normal Pressure Hydrocephalus Treatment by AcetazolamideRecruitingNCT02163330Phase 3
20The CSF Shunt Entry Site TrialRecruitingNCT02425761Phase 3
21Clinical Value of Noninvasive Intracranial Pressure MeasurementRecruitingNCT02130219Phase 2, Phase 3
22Quantitative Characterization of Safe Irrigation for Ventricular Shunt CathetersRecruitingNCT02651337Phase 3
23Transfusion of Prematures TrialRecruitingNCT01702805Phase 3
24Ultra-early Tranexamic Acid After Subarachnoid Hemorrhage.RecruitingNCT02684812Phase 2, Phase 3
25Preterm Erythropoietin Neuroprotection Trial (PENUT Trial)RecruitingNCT01378273Phase 3
26A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV)RecruitingNCT01376778Phase 3
27EARLYdrain - Outcome After Early Lumbar CSF-drainage in Aneurysmal SAHActive, not recruitingNCT01258257Phase 3
28Caffeine for Apnea of Prematurity (CAP)Active, not recruitingNCT00182312Phase 3
29Isoflurane-induced Neuroinflammation in Children With HydrocephalusEnrolling by invitationNCT02512809Phase 3
30ETV Versus Shunt Surgery in Normal Pressure HydrocephalusTerminatedNCT00946127Phase 3
31Positron Emission Tomography Imaging of Brain Amyloid in Normal Pressure HydrocephalusTerminatedNCT01092546Phase 3
32Study to Evaluate Efficacy of Shunt Operation for Idiopathic Normal Pressure HydrocephalusCompletedNCT00221091Phase 2
33Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid HemorrhageRecruitingNCT01098890Phase 2
34A Study Comparing Two Treatments for Infants With HydrocephalusActive, not recruitingNCT00652470Phase 2
35Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm InfantsActive, not recruitingNCT00875758Phase 2
36WEANING-Study: "Weaning by Early Versus lAte Tracheostomy iN supratentorIal iNtracerebral BleedingsTerminatedNCT01176214Phase 2
37Effect of Intraventricular tPA Following Aneurysmal Subarachnoid HemorrhageWithdrawnNCT01878136Phase 1, Phase 2
38Phase 1 Clinical Trial of PNEUMOSTEM® Treatment in Premature Infants With Intraventricular HemorrhageRecruitingNCT02274428Phase 1
39Treatment of Subarachnoid Hemorrhage With Human AlbuminTerminatedNCT01747408Phase 1
40Cerebrospinal Fluid Proteome in HydrocephalusCompletedNCT02016352
41A Study Comparing Shunt Placement Versus Endoscopic Third Ventriculostomy in the Treatment of HydrocephalusCompletedNCT01115270
42BIS Monitoring of Patients With HydrocephalusCompletedNCT02575105
43Predictive Value of Flow MRI in Normal Pressure Hydrocephalus SurgeryCompletedNCT01815775Phase 0
44A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure HydrocephalusCompletedNCT01570257
45Third Ventriculostomy Versus Shunt for Children With HydrocephalusCompletedNCT01801267
46Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)CompletedNCT01265251
47Vascular Risk Factors in INPH-patientsCompletedNCT01850914
48Magnetic Resonance Imaging (MRI) of Ventriculomegaly: Morphology and OutcomeCompletedNCT00870675
49Study of Shunt Flow Sensor Accuracy in Extra-ventricular Drains.CompletedNCT01108965
50Monitoring Patient Cerebro-Spinal Fluid Drainage With an Ultrasonic Flow SensorCompletedNCT00652197

Search NIH Clinical Center for Hydrocephalus


Cochrane evidence based reviews: hydrocephalus

Genetic Tests for Hydrocephalus

About this section

Anatomical Context for Hydrocephalus

About this section

MalaCards organs/tissues related to Hydrocephalus:

33
Brain, Spinal cord, Lung, Eye, Breast, Prostate, Testes

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Hydrocephalus:
id TissueAnatomical CompartmentCell Relevance
1 BrainChoroid PlexusChoroid Plexus Progenitor Cells Affected by disease
2 BrainChoroid PlexusMature Choroid Plexus Cells Affected by disease

Animal Models for Hydrocephalus or affiliated genes

About this section

MGI Mouse Phenotypes related to Hydrocephalus:

38 (show all 20)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.5DPH1, FOXC1, L1CAM, PTEN, TP53
2MP:00020069.1AKT3, DPH1, MAPT, PIK3R2, PTEN, TP53
3MP:00053709.0CCND2, DPH1, FLNA, FOXC1, PTEN, TP53
4MP:00053818.8DPH1, FLNA, FOXC1, POMGNT1, PTEN, TP53
5MP:00028738.5AKT3, FLNA, FOXC1, MAPT, NTF3, PTEN
6MP:00053698.4FOXC1, HYDIN, MAPT, NTF3, PIK3R2, POMGNT1
7MP:00053888.0DPH1, FLNA, FOXC1, HYDIN, NTF3, PTEN
8MP:00053828.0DPH1, FLNA, FOXC1, HYDIN, L1CAM, MAPT
9MP:00053907.9DPH1, FLNA, FOXC1, HYDIN, L1CAM, PTEN
10MP:00053917.8CCND2, DPH1, FLNA, FOXC1, L1CAM, MAPT
11MP:00053977.6AKT3, CCND2, DPH1, FLNA, HYDIN, MAPT
12MP:00053767.4AKT3, CCND2, DPH1, FANCB, FLNA, FOXC1
13MP:00053857.4AKT3, CCND2, FLNA, FOXC1, HYDIN, MAPT
14MP:00053897.3AKT3, CCND2, FANCB, FLNA, FOXC1, HYDIN
15MP:00053847.2AKT3, DPH1, FANCB, FLNA, FOXC1, HYDIN
16MP:00053867.1AKT3, AP1S2, CCND2, FLNA, HYDIN, L1CAM
17MP:00107686.7AKT3, CCND2, DPH1, FLNA, FOXC1, HYDIN
18MP:00053786.6AKT3, DPH1, FANCB, FLNA, FOXC1, HYDIN
19MP:00036316.5AKT3, AP1S2, CCND2, DPH1, FLNA, FOXC1

Publications for Hydrocephalus

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Articles related to Hydrocephalus:

(show top 50)    (show all 2070)
idTitleAuthorsYear
1
Polymorphic variants of the HSD11B1 gene may be involved in adverse metabolic effects of glucocorticoid replacement therapy in Addison's disease. (27083553)
2016
2
The Supportive Role of Insulin-Like Growth Factor-I in the Differentiation of Murine Mesenchymal Stem Cells into Corneal-Like Cells. (27050039)
2016
3
Adult Stem Cells and Skeletal Muscle Regeneration. (26122100)
2015
4
The expression of CDK1 is associated with proliferation and can be a prognostic factor in epithelial ovarian cancer. (25910705)
2015
5
Incident ischemic heart disease and recent occupational exposure to particulate matter in an aluminum cohort. (23982120)
2014
6
SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. (23388826)
2013
7
Echocardiographic measurement of cardiac valvular thickness in healthy cows, cows with bacterial endocarditis, and cows with cardiorespiratory diseases. (24252809)
2013
8
A case of dermatopathic lymphadenopathy associated with hypereosinophilic syndrome. (22499479)
2012
9
CNS involvement at the onset of primary hemophagocytic lymphohistiocytosis. (22422896)
2012
10
Long-term cardiovascular outcomes in patients with angina pectoris presenting with bundle branch block. (21439535)
2011
11
Circulating ApoE level is independently associated with urinary albumin excretion in type 2 diabetic patients. (22185986)
2011
12
Association between plasma asymmetrical dimethylarginine activity and severity of aortic valve stenosis. (20625307)
2011
13
Anesthetic experience in a pediatric patient with mastocytosis. (22148097)
2011
14
HBs seroconversion in a patient with acute hepatitis B treated with entecavir during immunosuppression against severe bronchiolitis obliterans in the course of chronic graft versus host disease. (20403727)
2010
15
Characterization of high molecular weight multimeric states of human haptoglobin and hemoglobin-based oxygen carriers by high-mass MALDI MS. (19296479)
2009
16
Newly discovered mutations in the GALNT3 gene causing autosomal recessive hyperostosis-hyperphosphatemia syndrome. (19297793)
2009
17
19q13.11 deletion syndrome: a novel clinically recognisable genetic condition identified by array comparative genomic hybridisation. (19126570)
2009
18
Demyelinating optic neuritis in children. (18936195)
2009
19
Evolution and selection of human leukocyte antigen alleles by Plasmodium falciparum infection. (18824049)
2008
20
Molecular and histological changes following central retinal artery occlusion in a mouse model. (18639547)
2008
21
Tranilast attenuates connective tissue growth factor-induced extracellular matrix accumulation in renal cells. (16528248)
2006
22
A polymorphism in the adiponectin gene influences adiponectin expression levels in visceral fat in obese subjects. (16231017)
2006
23
Understanding cell death: a challenge for biomedicine]. (16776320)
2005
24
Twenty-four vs. forty-eight weeks of re-therapy with interferon alpha 2b and ribavirin in interferon alpha monotherapy relapsers with chronic hepatitis C. (14625812)
2003
25
Ellipsomyxa gobii gen. et sp. n. (Myxozoa: Ceratomyxidae) in the common goby Pomatoschistus microps (Teleostei: Gobiidae) from Denmark. (14971595)
2003
26
Dynamic methylation of histone H3 at lysine 4 in transcriptional regulation by the androgen receptor. (14627807)
2003
27
Deficient natural killer cell cytotoxicity in patients with IKK- gamma/NEMO mutations. (12045264)
2002
28
-344C/T polymorphism of CYP11B2 gene in Italian patients with idiopathic low renin hypertension. (11587161)
2001
29
The structure of an entire noncovalent immunoglobulin kappa light-chain dimer (Bence-Jones protein) reveals a weak and unusual constant domains association. (10091599)
1999
30
Early diagnosis of subependymal giant cell astrocytoma in patients with tuberous sclerosis. (9568761)
1998
31
A third case of a low-grade endometrial stromal sarcoma with a t(7;17)(p14 approximately 21;q11.2 approximately 21). (9309124)
1997
32
Extended right trisegmentectomy for hilar bile duct carcinoma. (9261589)
1997
33
Successful treatment of infantile hemangiomas with interferon-alpha-2b. (9201147)
1997
34
Flicker parameters are different for suppression of myopia and hyperopia. (9373666)
1997
35
Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization. (9135136)
1997
36
Congenital lymphocytic choriomeningitis virus infection. (8634744)
1996
37
Development of selective low-density lipoprotein (LDL) apheresis system: immobilized polyanion as LDL-specific adsorption for LDL apheresis system. (8853808)
1996
38
Peroxisome proliferator-activated receptors: finding the orphan a home. (8056148)
1994
39
Long-term outcome in surgically treated encephalocele. (8362349)
1993
40
Heterogeneous Epstein-Barr virus infection patterns in peripheral T-cell lymphoma of angioimmunoblastic lymphadenopathy type. (1327284)
1992
41
Biliary tract disease in the aged. (1855163)
1991
42
Isolation of complementary DNA clones for genes exhibiting reduced expression after treatment of mouse teratocarcinoma stem cells with a tumor-promoting phorbol ester. (2821315)
1987
43
Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors. (6589029)
1984
44
Congenital angiodysplasia with skeletal affection. (7368842)
1980
45
The surgical approach to canine intervertebral disc disease. (4795128)
1973
46
Traditional chinese medicine in the treatment of thromboangiitis obliterans. Report of 136 cases. (5678364)
1968
47
48
49
50

Variations for Hydrocephalus

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Clinvar genetic disease variations for Hydrocephalus:

5
id Gene Variation Type Significance SNP ID Assembly Location
1DPH1NM_001383.3(DPH1): c.701T> C (p.Leu234Pro)single nucleotide variantLikely pathogenic, Pathogenicrs730882250GRCh37Chr 17, 1943054: 1943054

Expression for genes affiliated with Hydrocephalus

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Search GEO for disease gene expression data for Hydrocephalus.

Pathways for genes affiliated with Hydrocephalus

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Pathways related to Hydrocephalus according to GeneCards Suite gene sharing:

(show all 22)
idSuper pathwaysScoreTop Affiliating Genes
19.9FOXC1, L1CAM, ZIC3
29.8AKT3, AP1S2, PIK3R2
39.6FLNA, PIK3R2, PTEN
49.5AKT3, PTEN, TP53
59.5AKT3, CCND2, PIK3R2, TP53
6
Show member pathways
9.4AKT3, CCND2, PIK3R2, PTEN
79.4AKT3, FLNA, PIK3R2, TP53
8
Show member pathways
9.3AKT3, FLNA, PIK3R2, TP53
9
Show member pathways
9.3AKT3, FLNA, PIK3R2, TP53
109.2AKT3, PIK3R2, PTEN, TP53
119.2AKT3, PIK3R2, PTEN, TP53
12
Show member pathways
9.2AKT3, PIK3R2, PTEN, TP53
139.2AKT3, PIK3R2, PTEN, TP53
149.2AKT3, PIK3R2, PTEN, TP53
15
Show member pathways
9.1AKT3, CCND2, PIK3R2, PTEN, TP53
16
Show member pathways
9.1AKT3, CCND2, PIK3R2, PTEN, TP53
179.1AKT3, CCND2, PIK3R2, PTEN, TP53
18
Show member pathways
9.1AKT3, CCND2, PIK3R2, PTEN, TP53
198.9MAPT, NTF3, PTEN, TP53
208.8AKT3, FLNA, MAPT, NTF3, TP53
21
Show member pathways
8.8AKT3, NTF3, PIK3R2, PTEN, TP53
228.7AKT3, PIK3R2, PTEN, STK36, TP53

GO Terms for genes affiliated with Hydrocephalus

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Biological processes related to Hydrocephalus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription factor import into nucleusGO:004299310.0FLNA, PIK3R2

Sources for Hydrocephalus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet