MCID: HYD012
MIFTS: 44

Hydrops Fetalis malady

Categories: Genetic diseases, Rare diseases, Fetal diseases, Immune diseases

Aliases & Classifications for Hydrops Fetalis

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Aliases & Descriptions for Hydrops Fetalis:

Name: Hydrops Fetalis 48 27 50 68
Hydrops Fetalis Nonimmune 48 27
Familial Non-Immune Hydrops Fetalis 48
 
Hydrops Fetalis, Non-Immune 68
Idiopathic Hydrops Fetalis 48

Classifications:



External Ids:

ICD1030 P56, P56.0, P56.9

Summaries for Hydrops Fetalis

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NIH Rare Diseases:48 Hydrops fetalis is a serious condition in which abnormal amounts of fluid build up in two or more body areas of a fetus or newborn. There are two types of hydrops fetalis: immune and nonimmune. Immune hydrops fetalis is a complication of a severe form of Rh incompatibility. Rh compatibility causes massive red blood cell destruction, which leads to several problems, including total body swelling. Severe swelling can interfere with how the body organs work. Nonimmune hydrops fetalis occurs when a disease or medical condition disrupts the body's ability to manage fluid. There are three main causes for this type: heart or lung problems, severe anemia (thalassemia), and genetic defects, including Turner syndrome. The exact cause depends on which form a baby has. Last updated: 1/25/2012

MalaCards based summary: Hydrops Fetalis, also known as hydrops fetalis nonimmune, is related to hepatitis and hydrops fetalis, nonimmune, and has symptoms including joint swelling, joint swelling and fetal tachycardia. An important gene associated with Hydrops Fetalis is NEU1 (Neuraminidase 1), and among its related pathways are Lysosome and Glycosaminoglycan metabolism. Affiliated tissues include heart, placenta and lung, and related mouse phenotype homeostasis/metabolism.

Wikipedia:71 Hydrops fetalis is a condition in the fetus characterized by an accumulation of fluid, or edema, in at... more...

Related Diseases for Hydrops Fetalis

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Diseases related to Hydrops Fetalis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 128)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis30.0GPI, HBA1
2hydrops fetalis, nonimmune12.7
3immune hydrops fetalis12.4
4hydrops fetalis anemia immune disorder absent thumb12.0
5mucopolysaccharidosis vii11.5
6fetal edema11.4
7pyruvate kinase deficiency11.3
8glucose phosphate isomerase deficiency11.3
9achondrogenesis, type ii or hypochondrogenesis11.1
10hemoglobin h disease, nondeletional11.1
11semmekrot haraldsson weemaes syndrome11.0
12gaucher disease, perinatal lethal11.0
13greenberg skeletal dysplasia11.0
14chondrodysplasia, blomstrand type11.0
15porphyria, congenital erythropoietic11.0
16thalassemias, alpha-11.0
17lymphangiectasia, pulmonary, congenital11.0
18short-rib thoracic dysplasia 1211.0
19hypochondrogenesis11.0
20fetal parvovirus syndrome11.0
21thalassemia10.4
22chorioangioma10.3
23teratoma10.2
24mucopolysaccharidosis10.2
25lysosomal storage disease10.2
26hemophagocytic lymphohistiocytosis10.1
27down syndrome10.1
28syphilis10.1
29pulmonary sequestration10.1
30diamond-blackfan anemia10.0
31lymphedema10.0
32cerebritis10.0
33mediastinitis10.0
34congenital syphilis10.0
35cardiomyopathy10.0
36endocardial fibroelastosis10.0
37sacrococcygeal teratoma10.0
38congenital dyserythropoietic anemia10.0
39hemoglobinopathy10.0
40polyhydramnios10.0
41herpes simplex10.0
42cytomegalovirus infection10.0
43tetralogy of fallot9.9
44galactosialidosis9.9
45hemochromatosis9.9
46ebstein anomaly9.9
47hemangioma9.9
48hydrocephalus9.9
49leukemia9.9
50congenital hypothyroidism9.9

Graphical network of the top 20 diseases related to Hydrops Fetalis:



Diseases related to hydrops fetalis

Symptoms & Phenotypes for Hydrops Fetalis

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UMLS symptoms related to Hydrops Fetalis:


joint swelling, fetal tachycardia, fetal bradycardia

MGI Mouse Phenotypes related to Hydrops Fetalis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.9GBE1, GPI, GUSB, NEU1, PIEZO1

Drugs & Therapeutics for Hydrops Fetalis

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Drugs for Hydrops Fetalis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Betamethasoneapproved, vet_approvedPhase 1, Phase 2183378-44-99782
Synonyms:
.beta.-Methasone
.beta.-Methasone alcohol
1,4-Pregnadiene-3,20-dione-9alpha-fluoro-16 beta-methyl-11 beta,17alpha,21-triol
16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione
16β-Methyl-1,4-pregnadiene-9α-fluoro-11β,17α,21-triol-3,20-dione
24024-03-1
34166_FLUKA
34166_RIEDEL
378-44-9
4-08-00-03501 (Beilstein Handbook Reference)
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
9-Fluoro-16.beta.-methylprednisolone
9-Fluoro-16beta-methylprednisolone
9-Fluoro-16β-methylprednisolone
9-alpha-Fluoro-16-beta-methylprednisolone
9.alpha.-Fluoro-16.beta.-methylprednisolone
9alpha-Fluoro-16 beta-methyl-prednisolone
9alpha-Fluoro-16beta-methylprednisolone
9α-Fluoro-16β-methylprednisolone
AC1L1EYE
AC1L1TT4
AC1Q5HJZ
AKOS001582690
AR-1A7284
AR-1H5595
B1837
B7005_SIAL
B7005_SIGMA
B9675_SIAL
BIDD:PXR0047
BPBio1_000533
BRD-A35108200-001-04-7
BRD-K39188321-001-03-9
BRN 3176546
BSPBio_000483
Bebate
Becort
Bedifos
Betacorlan
Betacortril
Betadexamethasone
Betafluorene
Betamamallet
Betametasona
Betametasona [INN-Spanish]
Betametasone
Betametasone [DCIT]
Betamethasone
Betamethasone (JP15/USP/INN)
Betamethasone Base
Betamethasone Valearate
Betamethasone [USAN:BAN:INN:JAN]
Betamethasone [USAN:INN:BAN:JAN]
Betamethasone alcohol
Betamethasone cream
Betamethasonum
Betamethasonum [INN-Latin]
Betamethasonvalerat Mikron
Betamethazone
Betapredol
Betasolon
Betnelan
 
Betsolan
C22H29FO5
CHEBI:3077
CHEMBL632
CID3003
CID9782
CPD000339803
Celestene
Celeston
Celestona
Celestone
Celestone Syrup and Tablets
Celestone, Betadexamethasone, Flubenisolone, Sch-4831, NCS-39470, Betamethasone
Cellestoderm
Cidoten
D00244
D1961
DB00443
Desacort-Beta
EINECS 206-825-4
Flubenisolone
HMS1569I05
HSDB 3015
Hormezon
I06-0121
KST-1A3042
LS-118466
LT00441022
Luxiq
Luxiqo
MLS-0310139.0001
MLS000686794
MLS000859943
MLS001066413
MLS001332616
MLS002153244
Methazon
MolPort-003-845-025
MolPort-007-981-051
NCGC00164401-01
NCGC00164401-02
NSC 39470
NSC-39470
NSC39470
Prestwick0_000362
Prestwick1_000362
Prestwick2_000362
Prestwick3_000362
Prestwick_703
Rinderon
Rinderon (TN)
Rinderon A
S1500_Selleck
SAM002589959
SCH 4831
SCH-4831
SMP1_000043
SMR000058601
SMR000339803
SPBio_002404
UNII-9842X06Q6M
Valisone
Visubeta
ZINC03876136
beta-Methasone
beta-Methasone alcohol
betamethasone
2Hormone AntagonistsPhase 1, Phase 212778
3HormonesPhase 1, Phase 213979
4Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 1, Phase 212767
5glucocorticoidsPhase 1, Phase 24920
6Respiratory System AgentsPhase 1, Phase 24818
7Betamethasone-17,21-dipropionatePhase 1, Phase 2183
8Anti-Inflammatory AgentsPhase 1, Phase 210355
9Betamethasone benzoatePhase 1, Phase 2183
10Betamethasone sodium phosphatePhase 1, Phase 2183
11Anti-Asthmatic AgentsPhase 1, Phase 23369
12Betamethasone ValeratePhase 1, Phase 21832152-44-5
13
MentholapprovedPhase 123532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol

Interventional clinical trials:

idNameStatusNCT IDPhase
1Prenatal Steroids for Treatment of Congenital Cystic Adenomatoid Malformations (CCAM)TerminatedNCT00670956Phase 1, Phase 2
2In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)Not yet recruitingNCT02986698Phase 1
3Amniotic Fluid Tandem Mass Spectrometry for Pregnancies Complicated by NIH and Severe Symmetrical IUGRTerminatedNCT00143039Phase 1
4Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine TreatmentNot yet recruitingNCT02956564

Search NIH Clinical Center for Hydrops Fetalis

Genetic Tests for Hydrops Fetalis

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Genetic tests related to Hydrops Fetalis:

id Genetic test Affiliating Genes
1 Hydrops Fetalis27
2 Nonimmune Hydrops Fetalis27

Anatomical Context for Hydrops Fetalis

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MalaCards organs/tissues related to Hydrops Fetalis:

36
Heart, Placenta, Lung, Brain, Bone, Testes, Endothelial

Publications for Hydrops Fetalis

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Articles related to Hydrops Fetalis:

(show top 50)    (show all 559)
idTitleAuthorsYear
1
An international registry of survivors with Hb Bart's Hydrops Fetalis Syndrome. (28057638)
2017
2
Chylous Ascites in a Neonate with Hydrops Fetalis. (27670562)
2016
3
Hydrops Fetalis Associated with Compound Heterozygosity for Hb Zurich-Albisrieden (HBA2: C.178Ga88>a88C) and the Southeast Asian (- -(SEA)/) Deletion. (27686733)
2016
4
Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal Demise. (26914330)
2016
5
Hydrops fetalis in a congenital chagas case in a non-endemic area. (26940819)
2016
6
Pulmonary neuroendocrine cell hyperplasia in hemoglobin Bart-induced hydrops fetalis: A model for chronic intrauterine hypoxia. (27598399)
2016
7
Spontaneous repigmentation of silvery hair in an infant with congenital hydrops fetalis and hypoproteinemia. (27416089)
2016
8
EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis. (27400125)
2016
9
Cerebral Venous Engorgement in Hydrops Fetalis. (27403227)
2016
10
EP03.14: Using spatiotemporal image correlation with M-mode display to monitor ventricular systolic function of hydrops fetalis. (27644483)
2016
11
Lysosomal Storage Disorders in Nonimmune Hydrops Fetalis (NIHF): An Indian Experience. (27928775)
2016
12
Congenital Chylothorax: A Unique Presentation of Nonimmune Hydrops Fetalis in a Preterm Infant. (26945279)
2016
13
Hemoglobin Bart hydrops fetalis: A model for studying vascular changes in placental hypoxia. (27452444)
2016
14
A Rare Association of Non-Compaction of the Ventricular Myocardium, and Non-Immune Hydrops Fetalis. (27328555)
2016
15
Fetal Anemia and Hydrops Fetalis Associated with Homozygous Hb Constant Spring (HBA2: c.427Ta88>a88C). (26757782)
2016
16
Optimizing chronic transfusion therapy for survivors of hemoglobin Barts hydrops fetalis. (26732098)
2016
17
Perinatal and one-year outcomes of non-immune hydrops fetalis by etiology and age at diagnosis. (26712114)
2016
18
Society for maternal-fetal medicine (SMFM) clinical guideline #7: nonimmune hydrops fetalis. (25557883)
2015
19
Clinical Features of Neonates with Hydrops Fetalis. (26070120)
2015
20
Familial Hemophagocytic Lymphohistiocytosis Presenting as Hydrops Fetalis. (26199792)
2015
21
Intracardiac Fetal Transfusion for Parvovirus-Induced Hydrops Fetalis: A Salvage Procedure. (26446819)
2015
22
Perinatal-lethal Gaucher disease presenting as hydrops fetalis. (26327947)
2015
23
Hb H Hydrops Fetalis Syndrome Caused by Association of the -a88-(SEA) Deletion and Hb Constant Spring (HBA2: c.427Ta88>a88C) Mutation in a Chinese Family. (25897478)
2015
24
Rapid and reliable preimplantation genetic diagnosis of common hemoglobin Bart's hydrops fetalis syndrome and hemoglobin H disease determinants using an enhanced single-tube decaplex polymerase chain reaction assay. (26043722)
2015
25
Fetal critical aortic stenosis with natural improvement of hydrops fetalis due to spontaneous relief of severe restrictive atrial communication. (25772579)
2015
26
Non-immune Hydrops fetalis due to Parvovirus B19 Infection in 2 Extremely Preterm Infants: Perinatal Management and Long-term Neurodevelopmental Outcome. (25830498)
2015
27
Maternal and fetal capillary malformation-arteriovenous malformation (CM-AVM) due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis. (26096958)
2015
28
Congenital Disorder of Glycosylation (CDG) Presenting as Non-immune Hydrops Fetalis. (26365158)
2015
29
Neuropathologic Characterization of Pontocerebellar Hypoplasia Type 6 Associated With Cardiomyopathy and Hydrops Fetalis and Severe Multisystem Respiratory Chain Deficiency due to Novel RARS2 Mutations. (26083569)
2015
30
Etiology of non-immune hydrops fetalis: An update. (25712632)
2015
31
Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis. (26333996)
2015
32
Antenatal diagnosis of idiopathic arterial calcification with hydrops fetalis. (25851317)
2015
33
Single-tube nonaplex microsatellite PCR panel for preimplantation genetic diagnosis of Hb Bart's hydrops fetalis syndrome. (25641621)
2015
34
KLF1-null neonates display hydrops fetalis and a deranged erythroid transcriptome. (25724378)
2015
35
Nonimmune hydrops fetalis with ebstein anomaly. (25148508)
2014
36
Primary Endocardial Fibroelastosis and Nonimmune Hydrops Fetalis: Case Report with Autopsy. (25517884)
2014
37
I+-thalassemia-associated hydrops fetalis: A rare cause of thyrotoxic cardiomyopathy. (25510540)
2014
38
Mediastinal teratoma with hydrops fetalis in a newborn and development of chronic respiratory insufficiency. (25435854)
2014
39
De novo Reciprocal Translocation t(5;11)(q22;p15) Associated with Hydrops Fetalis (Reciprocal Translocation and Hydrops Fetalis). (25289481)
2014
40
Non-immune hydrops fetalis without anemia due to parvovirus B19. (24140219)
2014
41
Hydrops fetalis in a preterm newborn heterozygous for the c.4A>G SHOC2 mutation. (24458587)
2014
42
Thoracic ganglioneuromas resulting in nonimmune hydrops fetalis. (25032061)
2014
43
Non-immune hydrops fetalis as a diagnostic and survival problems: what do we tell the parents? (25294712)
2014
44
Accessory diaphragm associated with non-immune hydrops fetalis. (25100808)
2014
45
Transient myeloproliferative disorder and non-immune hydrops fetalis in a neonate with trisomy 21. (24473698)
2014
46
Foetal supraventricular tachycardia with hydrops fetalis: a role for direct intraperitoneal amiodarone. (24811422)
2014
47
Prenatal control of Hb Bart's hydrops fetalis: a two-year experience at a mainland Chinese hospital. (24766075)
2014
48
Histological, biochemical, and genetic characterization of early-onset fulminating sialidosis type 2 in a Korean neonate with hydrops fetalis. (23433491)
2014
49
Coronary arteriovenous fistula causing hydrops fetalis. (25247099)
2014
50
Inferior vena cava Doppler indices in fetuses with hemoglobin Bart's hydrops fetalis. (24609794)
2014

Variations for Hydrops Fetalis

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Clinvar genetic disease variations for Hydrops Fetalis:

5
id Gene Variation Type Significance SNP ID Assembly Location
1NEU1NM_000434.3(NEU1): c.353-2A> GSNVPathogenicrs864309513GRCh37Chr 6, 31829229: 31829229
2NEU1NM_000434.3(NEU1): c.1170C> G (p.Tyr390Ter)SNVPathogenicrs746607723GRCh37Chr 6, 31827574: 31827574
3GUSBNM_000181.3(GUSB): c.1144C> T (p.Arg382Cys)SNVLikely pathogenic, Pathogenicrs121918173GRCh37Chr 7, 65439613: 65439613
4GUSBNM_000181.3(GUSB): c.1069C> T (p.Arg357Ter)SNVLikely pathogenic, Pathogenicrs121918185GRCh37Chr 7, 65439688: 65439688

Expression for genes affiliated with Hydrops Fetalis

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Search GEO for disease gene expression data for Hydrops Fetalis.

Pathways for genes affiliated with Hydrops Fetalis

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GO Terms for genes affiliated with Hydrops Fetalis

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Cellular components related to Hydrops Fetalis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lysosomal lumenGO:00432029.6GUSB, NEU1
2extracellular exosomeGO:00700628.2GBE1, GPI, GUSB, HBA1, NEU1

Biological processes related to Hydrops Fetalis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1carbohydrate metabolic processGO:00059759.5GPI, GUSB

Sources for Hydrops Fetalis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet