MCID: HYP065
MIFTS: 51

Hyperaldosteronism malady

Categories: Genetic diseases, Endocrine diseases, Rare diseases

Aliases & Classifications for Hyperaldosteronism

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Aliases & Descriptions for Hyperaldosteronism:

Name: Hyperaldosteronism 11 26 49 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:446
ICD1029 E26, E26.9
ICD9CM31 255.1, 255.10
MeSH38 D006929
NCIt44 C113213

Summaries for Hyperaldosteronism

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Disease Ontology:11 An adrenal gland hyperfunction disease that results in the overproduction of aldosterone by the adrenal glands.

MalaCards based summary: Hyperaldosteronism is related to pheochromocytoma and myocardial infarction, and has symptoms including cushingoid facies An important gene associated with Hyperaldosteronism is CYP11B2 (Cytochrome P450 Family 11 Subfamily B Member 2), and among its related pathways are Steroid hormone biosynthesis and Renin secretion. The drugs spironolactone and spironolactone pwdr have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, testes and prostate, and related mouse phenotypes are growth/size/body region and renal/urinary system.

Wikipedia:70 Hyperaldosteronism, also aldosteronism, is a medical condition wherein too much aldosterone is produced... more...

Related Diseases for Hyperaldosteronism

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Diseases in the Hyperaldosteronism family:

Hyperaldosteronism, Familial, Type Ii Hyperaldosteronism, Familial, Type Iii
Hyperaldosteronism, Familial, Type Iv Familial Hyperaldosteronism

Diseases related to Hyperaldosteronism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 162)
idRelated DiseaseScoreTop Affiliating Genes
1pheochromocytoma29.2MEN1, NPPA, POMC
2myocardial infarction28.4ACE, AGTR1, NPPA, NR3C2, REN
3hyperaldosteronism, familial, type iii12.4
4familial hyperaldosteronism12.3
5hyperaldosteronism, familial, type iv12.1
6hyperaldosteronism, familial, type ii12.1
7aldosteronism, glucocorticoid-remediable12.0
8conn's syndrome11.6
9liddle syndrome11.0
10hyper-reninism10.9
11liddle syndrome, scnn1b-related10.7
12liddle syndrome, scnn1g-related10.7
13silver-russell syndrome due to 7p11.2p13 microduplication10.5NPPA, REN
14repetitive motion disorders10.5NPPA, REN
15achromatopsia10.4NPPA, REN
16carotid artery disease10.4POMC, REN
17gallbladder adenoma10.4POMC, REN
18hypotelorism cleft palate hypospadias10.4ACE, REN
19dressler's syndrome10.4POMC, REN
20cystic kidney disease10.4ACE, REN
21atrial septal defect 7, with or without av conduction defects10.4ACE, REN
22acute liver failure10.4NPPA, REN
23adenoma10.3
24actinic lichen planus10.3POMC, REN
25casr-related disorders10.3ACE, AGTR1
26bestrophinopathy10.3REN, SLC12A3
27fibula aplasia complex brachydactyly10.3ACE, AGTR1
28post-infectious myocarditis10.3ACE, AGTR1
29degenerative myopia10.3ACE, REN
30voyeurism10.3ACE, REN
31pseudomarfanism10.3ACE, NPPA
32embryoma10.3ACE, NPPA
33bladder neck cancer10.3NPPA, REN
34agammaglobulinemia 610.2ACE, AGTR1
35plica syndrome10.2ACE, REN
36bronchiectasis with or without elevated sweat chloride 310.2CYP11B2, NR3C2, REN
37retinal vasculitis10.2REN, SLC12A3
38mucinous tubular and spindle renal cell carcinoma10.2REN, SLC12A3
39peritoneal mesothelioma10.2CYP11B1, CYP11B2, POMC
40todd's paralysis10.2ACE, NPPA
41glioma susceptibility 110.2CYP11B1, CYP11B2, POMC
42aphthous stomatitis10.2ACE, NR3C2
43perrault syndrome10.2AGTR1, NR3C2, REN
44craniopharyngioma10.2POMC, REN
45benign neonatal seizures10.2ACE, REN
46hypopigmentation of eyelid10.2ACE, AGTR1
47joint disorders10.2ACE, AGTR1
48dfna2 nonsyndromic hearing loss10.1CYP17A1, POMC
49cataract 21, multiple types10.1NR3C2, POMC, REN
50iridocyclitis10.1ACE, CYP11B1

Comorbidity relations with Hyperaldosteronism via Phenotypic Disease Network (PDN):


Hypertension, EssentialHeart Disease
Acute Cystitis

Graphical network of the top 20 diseases related to Hyperaldosteronism:



Diseases related to hyperaldosteronism

Symptoms for Hyperaldosteronism

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UMLS symptoms related to Hyperaldosteronism:


cushingoid facies

Drugs & Therapeutics for Hyperaldosteronism

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Drugs for Hyperaldosteronism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 97)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Bromocriptineapproved, investigationalPhase 43125614-03-331101
Synonyms:
(5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-3',6',18-trioxoergotaman
(5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione
(5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-2'-(propan-2-yl)-3',6',18-trioxoergotaman
(5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman
(6aR,9R)-5-Bromo-N-((2R,5S,10aS,10bS)-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-alpha-(2-methylpropyl)ergotamin-3',6',18-trione
2-Bromo-alpha-ergocryptine
2-Bromo-alpha-ergokryptin
2-Bromo-alpha-ergokryptine
2-Bromoergocryptine Methanesulfonate
2-Bromoergokryptine
2-bromo-α-ergocryptine
2-bromo-α-ergokryptin
2-bromo-α-ergokryptine
22260-51-1 (mesylate (salt))
25614-03-3
AC-13601
AC1L1KXS
AC1Q2716
Alti-Bromocriptine
Apo-Bromocriptine
BIDD:GT0464
BPBio1_001131
BRD-K14496212-001-01-1
Bagren
Biomol-NT_000005
Bromergocryptine
Bromocriptin
Bromocriptina
Bromocriptina [INN-Spanish]
Bromocriptine (USAN/INN)
Bromocriptine Methanesulfonate
Bromocriptine [BAN]
Bromocriptine [USAN:BAN:INN]
 
Bromocriptine methanesulfonate
Bromocriptinum
Bromocriptinum [INN-Latin]
Bromocryptin
Bromocryptine
Bromoergocriptine
Bromoergocryptine
C06856
C32H40BrN5O5
CB-154
CCRIS 3244
CHEBI:3181
CHEMBL493
CID31101
D03165
DB01200
EINECS 247-128-5
Ergocryptine, 2-bromo- (8CI)
Ergoset
LS-64540
Lopac0_000171
MolPort-002-512-064
NCGC00024584-04
NCI60_001365
NSC169774
PDSP2_001500
Parlodel
Parlodel Snaptabs
Prestwick0_000121
Prestwick1_000121
Prestwick2_000121
SPBio_002101
UNII-3A64E3G5ZO
bromocriptine
nchembio873-comp18
2
DopamineapprovedPhase 4375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
3
SpironolactoneapprovedPhase 4, Phase 32221952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
4
CaptoprilapprovedPhase 43262571-86-244093
Synonyms:
(2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline
(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(3-Mercapto-2-methyl-1-oxo-propyl)-L-proline
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
1-((2S)-3-Mercapto-2-methylpropionyl)-L-proline
1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
1-(D-3-Mercapto-2-methyl-1-oxopropyl)-L-proline (S,S)
1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline
1j37
3-Mercapto-2-methylpropionyl-proline
62571-86-2
AC-12047
AC1L2B4L
AC1Q29GZ
AC1Q5R48
Acediur
Aceplus
Acepress
Acepril
Alopresin
Apopril
Apopril (TN)
Asisten
BB_NC-2104
BIM-0050290.0001
BPBio1_000063
BRD-K54529596-001-04-0
BSPBio_000057
BSPBio_002976
C 4042
C4042_SIAL
C4042_SIGMA
C8856_SIAL
C9H15NO3S
CHEBI:3380
CHEMBL1560
CHEMBL82
CID44093
CP
CPD0-2067
CPD000059061
Capoten
Capoten (TN)
Captolane
Captopril (JP15/USP/INN)
Captopril [USAN:INN:BAN:JAN]
Captoprilum
Captoprilum [INN-Latin]
Captopryl
Captoril
Captril
Cesplon
D-2-Methyl-3-mercaptopropanoyl-L-proline
D-3-Mercapto-2-methylpropanoyl-L-proline
D-3-Mercapto-2-methylpropionylproline
D00251
DB01197
Dilabar
DivK1c_000208
EINECS 263-607-1
EU-0100302
FT-0082749
Garranil
Garranil (discontinued)
HMS1921C12
HMS2089P19
 
HMS2092I12
HMS500K10
HSDB 6527
Hipertil
Hypertil
IDI1_000208
Isopresol
KBio1_000208
KBio2_001168
KBio2_003736
KBio2_006304
KBio3_002196
KBioGR_001321
KBioSS_001168
L-Captopril
LS-137465
Lopac-C-4042
Lopac0_000302
Lopirin
Lopirin [Switzerland]
Lopril
MCO
MLS000069484
MLS001076488
MolPort-001-794-639
N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline
NCGC00015235-01
NCGC00015235-02
NCGC00023654-03
NCGC00023654-04
NCGC00023654-05
NCGC00023654-06
NCGC00023654-07
NCGC00023654-08
NCGC00023654-09
NCGC00023654-10
NINDS_000208
Prestwick3_000019
Prestwick_103
SA 333
SAM002564201
SMP1_000056
SMR000059061
SPBio_001022
SPECTRUM1500682
SQ 14,225
SQ 14225
SQ-14,225
SQ-14,534
SQ-14225
SQ-14534
ST079562
STK802012
Spectrum2_001211
Spectrum3_001388
Spectrum4_000811
Spectrum5_001587
Spectrum_000688
Tenosbon
Tensiomin
Tensobon
Tensoprel
UNII-9G64RSX1XD
UPCMLD-DP003
UPCMLD-DP003:001
X8Z
[2S]-1-[3-Mercapto-2-methylpropionyl]-L-proline
captopril
5
Epinephrineapproved, vet_approvedPhase 4, Phase 3, Phase 293351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
6
EplerenoneapprovedPhase 4, Phase 394107724-20-9150310, 443872
Synonyms:
107724-20-9
7alpha-methoxycarbonyl-3-oxo-9,11alpha-epoxy-17alpha-pregn-4-ene-21,17-carbolactone
AC-4213
AC1L9FDC
C12512
CGP-30083
CHEBI:31547
CHEBI:726453
CHEMBL1095097
CID443872
D01115
Eplerenone
 
Eplerenone (JAN/USAN/INN)
Epoxymexrenone
Inspra
Inspra (TN)
Inspra, Epoxymexrenone, CGP30083, SC-66110,Eplerenone
MolPort-003-986-216
NCGC00159559-01
NCGC00159559-02
S1707_Selleck
SC-66110
Selara
TL8000270
ZINC03985982
7
LosartanapprovedPhase 4282114798-26-43961
Synonyms:
(2-Butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol
(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol
114798-26-4
124750-99-8 (mono-potassium salt)
1H-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl-1H-imidazole-5-methanol
2-N-Butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5ylphenyl)benzyl]imidazole-5-methanol
2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole
2-n-butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]methyl]imidazole
AC1L1H3Q
BIDD:GT0286
BRD-K76205745-001-02-5
BSPBio_002695
C07072
C22H23ClN6O
CHEBI:6541
CHEMBL191
CID3961
CL23623
Cozaar
D08146
DB00678
DUP 89
DuP 89
DuP-753
HMS1922J13
HMS2093E22
Hyzaar
I14-9710
Jsp001094
KBio2_002193
 
KBio2_004761
KBio2_007329
KBio3_001915
KBioGR_001611
KBioSS_002193
L000351
LOSARTAN POTASSIUM
LS-78746
Lacidipine
Lortaan
Losartan
Losartan (INN)
Losartan Potassium
Losartan [INN:BAN]
Losartan monopotassium salt
Losartic
Losartic (TN)
MK-954
MK954
MolPort-003-666-553
NCGC00095125-01
NCGC00095125-02
NCGC00095125-03
Oprea1_644635
SPBio_001893
SPECTRUM1504268
Spectrum2_001677
Spectrum3_000998
Spectrum4_001126
Spectrum5_001466
Spectrum_001713
UNII-JMS50MPO89
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
losartan
losartan potassium
8Bronchodilator AgentsPhase 4, Phase 3, Phase 22856
9Adrenergic alpha-AgonistsPhase 4, Phase 3, Phase 21625
10MineralocorticoidsPhase 4, Phase 3, Phase 2352
11Mineralocorticoid Receptor AntagonistsPhase 4, Phase 3333
12diureticsPhase 4, Phase 31372
13Diuretics, Potassium SparingPhase 4, Phase 31827
14Angiotensin-Converting Enzyme InhibitorsPhase 4711
15Adrenergic AgonistsPhase 4, Phase 3, Phase 22877
16Insulin, Globin ZincPhase 44523
17Adrenergic AgentsPhase 4, Phase 3, Phase 25140
18insulinPhase 44524
19
protease inhibitorsPhase 4, Phase 25320
Synonyms:
 
protease inhibitors
20Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 2, Phase 312767
21HIV Protease InhibitorsPhase 4, Phase 25319
22Antihypertensive AgentsPhase 44095
23Natriuretic AgentsPhase 4, Phase 31645
24RacepinephrinePhase 4, Phase 3, Phase 2933
25HormonesPhase 4, Phase 3, Phase 213979
26Vasoconstrictor AgentsPhase 4, Phase 3, Phase 22027
27Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 222776
28Neurotransmitter AgentsPhase 4, Phase 3, Phase 217734
29Autonomic AgentsPhase 4, Phase 3, Phase 29774
30Epinephryl boratePhase 4, Phase 3, Phase 2933
31MydriaticsPhase 4, Phase 3, Phase 2763
32Antiparkinson AgentsPhase 41527
33Respiratory System AgentsPhase 4, Phase 3, Phase 24818
34Dopamine AgentsPhase 43759
35Dopamine agonistsPhase 4618
36Hormone AntagonistsPhase 4, Phase 2, Phase 312778
37Anti-Asthmatic AgentsPhase 4, Phase 3, Phase 23369
38Adrenergic beta-AgonistsPhase 4, Phase 3, Phase 21640
39Angiotensin II Type 1 Receptor BlockersPhase 41078
40CoagulantsPhase 41428
41AngiotensinogenPhase 41161
42Angiotensin Receptor AntagonistsPhase 41173
43Anti-Arrhythmia AgentsPhase 42969
44Fertility AgentsPhase 4493
45
Angiotensin IIPhase 4116268521-88-0, 11128-99-7172198, 65143
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
46KallikreinsPhase 425
47
Hydrocortisoneapproved, vet_approvedPhase 3, Phase 264050-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
48
Lidocaineapproved, vet_approvedPhase 2, Phase 31226137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
49Anti-Inflammatory AgentsPhase 2, Phase 310355
50
glycyrrhetinic acidPhase 2, Phase 39471-53-418526330
Synonyms:
18b-Glycyrrhetic acid
18b-Glycyrrhetinic acid
18b-Glycyrrhtinic acid
3-Glycyrrhetinic acid
3-Hydroxy-11-oxoolean-12-en-29-oate
3-Hydroxy-11-oxoolean-12-en-29-oic acid
3-Hydroxy-11-oxoolean-12-en-29-oic acid (ACD/Name 4.0)
3b-Hydroxy-11-oxo-Olean-12-en-30-oate
3b-Hydroxy-11-oxo-Olean-12-en-30-oic acid
3b-Hydroxy-11-oxoolean-12-en-30-oate
 
3b-Hydroxy-11-oxoolean-12-en-30-oic acid
Biosone
Enoxolone
Glycyrrhetic acid
Glycyrrhetin
Glycyrrhetinate
Glycyrrhetinic acid
Uralenic acid
a-Glycyrrhetinic acid
alpha-Glycyrrhetinic acid
b-Glycyrrhetic acid
beta-Glycyrrhetic acid

Interventional clinical trials:

(show top 50)    (show all 61)
idNameStatusNCT IDPhase
1Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary AldosteronismUnknown statusNCT02127840Phase 4
2The Therapeutic Effect of Bromocriptin in Patients With Primary AldosteronismUnknown statusNCT00451672Phase 4
3Does Aldosterone Cause Hypertension by a Non-Renal Mechanism?Unknown statusNCT00553722Phase 4
4Kallikrein-kinin (KKS) and Renin-angiotensin-aldosterone System (RAAS) in Primary AldosteronismCompletedNCT00155064Phase 4
5Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic AdrenalectomyCompletedNCT01959711Phase 4
6Aldosterone, Microvascular Function and Salt-sensitivityRecruitingNCT02068781Phase 4
7Aldosterone Antagonism and Microvascular FunctionRecruitingNCT01887119Phase 4
8SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan.CompletedNCT01096654Phase 3
9The Role of Mineralocorticoid Receptors in Vascular FunctionCompletedNCT00759525Phase 2, Phase 3
10Effectiveness of Eplerenone to Improve Target Organ Damage in Patients With Resistant Arterial HypertensionCompletedNCT00138944Phase 3
11Effect of Eplerenone on Endothelial Function in Metabolic SyndromeCompletedNCT01319344Phase 3
12Study of CS-3150 in Patients With Primary AldosteronismRecruitingNCT02885662Phase 3
13Dynamic Hormone Diagnostics in Endocrine DiseaseNot yet recruitingNCT02934399Phase 2, Phase 3
14Proof-of-concept for the Aldosterone Synthase Inhibitor LCI699 in Patients With Primary HyperaldosteronismCompletedNCT00732771Phase 2
15Abiraterone With Different Steroid Regimens for Side Effect Related to Mineralcorticoid Excess Prevention in Prostate Cancer Prior to ChemotherapyActive, not recruitingNCT01867710Phase 2
16Phase II Clinical Trial of Abiraterone Acetate Without Exogenous Glucocorticoids in Men With Castration-resistant Prostate Cancer With Correlative Assessment of Hormone Intermediates.Active, not recruitingNCT02025010Phase 2
17Postoperative Cardiovascular Index Change of Primary AldosteronismUnknown statusNCT00746070
18Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or FibrillationUnknown statusNCT01267747
19Metabolic Syndrome and Insulin Resistance in Primary AldosteronismUnknown statusNCT00173082
20Diagnostic Properties of Aldosterone-Renin Ratio in Primary Aldosteronism Among Hypertensives.Unknown statusNCT00407784
21Diagnosis of Primary Aldosteronism: Comparison of Post Captopril Active Renin Concentration and Plasma Renin ActivityUnknown statusNCT00917345
22D2 Dopamine Receptor on Human Aldosterone-Producing Adenoma and Its Role in Aldosterone Secretion and Cell ProliferationUnknown statusNCT00173446
23Parathyroid Hormone (PTH) Homeostasis in Bartter SyndromeUnknown statusNCT01021280
24Optimizing Diagnosis Of Primary AldosteronismCompletedNCT02755519
25Study of Myocardial Interstitial Fibrosis in HyperaldosteronismCompletedNCT02938910
26The Effect of Disease-specific Treatment on Bone Turnover Markers in Patients With Primary AldosteronismCompletedNCT02216721
27Primary Aldosteronism in General Practice: Organ Damage, Epidemiology and TreatmentCompletedNCT01728493
28Intraoperative Analysis of Cortisol During Adrenal Vein SamplingCompletedNCT01761344
29Study of Prevalence and Clinical Phenotype in Patients With Glucocorticoid-Remediable AldosteronismCompletedNCT00004354
30Natural History of Apparent Mineralocorticoid Excess SyndromeCompletedNCT00474942
31Adrenal Vein Sampling International Study (AVIS Study)CompletedNCT01234220
32Prevalence of Primary Aldosteronism in Patients With Resistant Hypertension in ChinaCompletedNCT01459042
33Etiology of Sleep Apnea-related Hyperaldosteronism - BP TreatmentCompletedNCT01897727
34Arterial Stiffness Index as a Predictor of Surgically Correctable Primary AldosteronismCompletedNCT01190501
35Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood PressureCompletedNCT00001176
36Diagnosis/Pathophysiology of Glucocorticoid Remediable Aldosteronism HypertensionCompletedNCT00005394
37Cardiovascular Evaluation of Adult PHA 1 PatientsCompletedNCT00646828
38Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIVCompletedNCT01407237
39Spironolactone to Decrease Potassium Wasting in Hypercalciurics on Thiazides DiureticsCompletedNCT00276289
40Primary Aldosteronism in Western NorwayRecruitingNCT02832388
41Glucose Metabolism in Subjects With Aldosterone-Producing AdenomasRecruitingNCT02362308
42Laparoscopic Adrenalectomy Versus Radiofrequency AblationRecruitingNCT02030587
43Renal Sympathetic Denervation From The Adventitia on HypertensionRecruitingNCT02642445
44Plasma Aldosterone Levels and Atrial Fibrillation Reduction (ALDO-AF Study)RecruitingNCT02804321
45Pharmacogenetic Study in Castration-resistant Prostate Cancer Patients Treated With Abiraterone AcetateRecruitingNCT01858441
46Omics Signature in the Diagnosis of HypertensionRecruitingNCT02772315
47The Role of Aldosterone on Augmented Exercise Pressor Reflex in HypertensionRecruitingNCT01996449
48Adrenal Tumors - Pathogenesis and TherapyRecruitingNCT00669266
4911C-Metomidate PET Versus Adrenal Vein Sampling in Primary AldosteronismActive, not recruitingNCT01567111
50Eplerenone in HIV Associated Abdominal Fat AccumulationActive, not recruitingNCT01405456

Search NIH Clinical Center for Hyperaldosteronism

Inferred drug relations via UMLS67/NDF-RT45:

Genetic Tests for Hyperaldosteronism

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Genetic tests related to Hyperaldosteronism:

id Genetic test Affiliating Genes
1 Hyperaldosteronism26

Anatomical Context for Hyperaldosteronism

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MalaCards organs/tissues related to Hyperaldosteronism:

35
Adrenal gland, Testes, Prostate, Kidney, Endothelial, Pituitary, Heart

Animal Models for Hyperaldosteronism or affiliated genes

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MGI Mouse Phenotypes related to Hyperaldosteronism:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053788.0ACE, AGTR1, CYP11B1, CYP11B2, MEN1, NR3C2
2MP:00053676.9ACE, AGTR1, CYP11B1, CYP11B2, NPPA, NR3C2
3MP:00053856.6ACE, AGTR1, CYP11B1, CYP11B2, KCNJ5, MEN1
4MP:00053766.2ACE, AGTR1, CYP11B1, CYP11B2, CYP17A1, MEN1

Publications for Hyperaldosteronism

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Articles related to Hyperaldosteronism:

(show top 50)    (show all 567)
idTitleAuthorsYear
1
Evaluation of a Recently Established Test for Familial Hyperaldosteronism Type 1. (27923252)
2016
2
Primary hyperaldosteronism: a case of unilateral adrenal hyperplasia with contralateral incidentaloma. (27417992)
2016
3
NCI-H295R cell line as in vitro model of hyperaldosteronism lacks functional KCNJ5 (GIRK4; Kir3.4) channels. (25998841)
2015
4
Novel somatic mutations in primary hyperaldosteronism are related to the clinical, radiological and pathological phenotype. (26252618)
2015
5
Laparoendoscopic single-site adrenalectomy in patients with primary hyperaldosteronism: A prospective study with long-term follow up. (26626099)
2015
6
The Vascular Surgeon's Experience with Adrenal Venous Sampling for the Diagnosis of Primary Hyperaldosteronism. (24355161)
2013
7
Evaluation of the oral fludrocortisone suppression test for diagnosing primary hyperaldosteronism in cats. (24627898)
2013
8
Mutations in KCNJ5 determines presentation and likelihood of cure in primary hyperaldosteronism. (24274318)
2013
9
Adrenal Diagnostics: An Endocrinologist's Perspective focused on Hyperaldosteronism. (24353356)
2013
10
Outcome of Surgery for Primary Hyperaldosteronism. (22286966)
2012
11
Primary hyperaldosteronism among Chinese hypertensive patients: how are we doing in a local district in Hong Kong. (22665682)
2012
12
Polymorphisms in CYP11B2 and CYP11B1 genes associated with primary hyperaldosteronism. (20339375)
2010
13
Hyperaldosteronism in Klotho-deficient mice. (20719979)
2010
14
Hyperaldosteronism in an adolescent with Gardner's syndrome. (19433155)
2009
15
Primary hyperaldosteronism in a domestic ferret with an adrenocortical adenoma. (19180717)
2008
16
Spironolactone versus eplerenone for the treatment of idiopathic hyperaldosteronism. (18312153)
2008
17
Further evidence for linkage of familial hyperaldosteronism type II at chromosome 7p22 in Italian as well as Australian and South American families. (18622235)
2008
18
Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II. (18307725)
2008
19
Contribution of CYP11B2, REN and AGT genes in genetic predisposition to arterial hypertension associated with hyperaldosteronism]. (18260994)
2008
20
Primary hyperaldosteronism due to adrenal microadenoma: a curable cause of refractory hypertension. (18584586)
2008
21
Primary hyperaldosteronism secondary to unilateral adrenal hyperplasia: an unusual cause of surgically correctable hypertension. A review of 30 cases. (17180480)
2007
22
Prevalence of primary hyperaldosteronism assessed by aldosterone/renin ratio and spironolactone testing. (15745200)
2005
23
Hyperaldosteronism and hypertension: ethnic differences. (15699471)
2005
24
Primary hyperaldosteronism, a mediator of progressive renal disease in cats. (15620809)
2005
25
Comparison of active renin concentration and plasma renin activity for the diagnosis of primary hyperaldosteronism in patients with an adrenal mass. (15080782)
2004
26
Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome). (11422106)
2001
27
Laparoscopic vs open adrenalectomy for the treatment of primary hyperaldosteronism. (10367872)
1999
28
Bilateral adrenal cortical adenomas in primary hyperaldosteronism. (9763101)
1998
29
Linkage analysis of familial hyperaldosteronism type II--absence of linkage to the gene encoding the angiotensin II receptor type 1. (9506777)
1998
30
The effect of surgical treatment on secondary hyperaldosteronism and relative hyperinsulinemia in primary hyperparathyroidism. (9625366)
1998
31
Primary hyperaldosteronism. Apropos of 2 cases]. (9538374)
1997
32
Aldosterone precursors and hypertension with hypokalemia and adrenal module non caused by primary hyperaldosteronism]. (8949378)
1996
33
Primary dexamethasone-suppressible hyperaldosteronism and hyperprolactinemia]. (1323053)
1992
34
Hyperreninemia and secondary hyperaldosteronism in a patient with pheochromocytoma and von Hippel-Lindau disease. (1436350)
1992
35
Dexamethasone-suppressible hyperaldosteronism: pathophysiology, clinical aspects, and new insights into the pathogenesis. (3037179)
1987
36
Aldosterone receptors in different types of primary hyperaldosteronism. (3034947)
1987
37
Quiz of the month. Secondary hyperaldosteronism caused by surreptitious vomiting, diuretic abuse, or Bartter's syndrome. (3631151)
1987
38
Mechanisms responsible for thirst and polyuria associated with primary hyperaldosteronism. (3117239)
1987
39
Role of exogenous factors in alterations of red cell Na+-Li+ exchange and Na+-K+ cotransport in essential hypertension, primary hyperaldosteronism, and hypokalemia. (3012766)
1986
40
Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism. (3882312)
1985
41
Hyperaldosteronism in ketoacidosis and in poorly controlled non-ketotic diabetes. (6809687)
1982
42
Cystic fibrosis presenting with chronic electrolyte depletion, metabolic alkalosis and hyperaldosteronism. (7146884)
1982
43
Amiloride in primary hyperaldosteronism. (7053305)
1982
44
Glucocorticoid-suppressible hyperaldosteronism: a clue to the missing hormone? (6268977)
1981
45
Familial, dexamethasone-suppressible, normokalemic hyperaldosteronism. (6987607)
1980
46
Primary hyperparathyroidism: possible cause of primary hyperaldosteronism in a 60-year-old woman. (6991517)
1980
47
Autosomal dominant transmission and absence of HLA linkage in dexamethasone suppressible hyperaldosteronism. (6102278)
1980
48
Effect of indomethacin in two siblings with a renin-dependent hypertension, hyperaldosteronism and hypokalemia. (7352042)
1980
49
Acute intermittent porphyria associated with inappropriate antidiuretic hormone secretion, hypokalemic alkalosis, and secondary hyperaldosteronism. (472850)
1979
50
Hyperreninemia and secondary hyperaldosteronism in pheochromocytomas. (762609)
1979

Variations for Hyperaldosteronism

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Expression for genes affiliated with Hyperaldosteronism

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Search GEO for disease gene expression data for Hyperaldosteronism.

Pathways for genes affiliated with Hyperaldosteronism

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GO Terms for genes affiliated with Hyperaldosteronism

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Biological processes related to Hyperaldosteronism according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1renin-angiotensin regulation of aldosterone productionGO:000201810.4AGTR1, REN
2cortisol biosynthetic processGO:003465110.3CYP11B1, CYP11B2
3aldosterone biosynthetic processGO:003234210.3CYP11B1, CYP11B2
4cellular response to potassium ionGO:003586510.3CYP11B1, CYP11B2
5secondary metabolite biosynthetic processGO:004455010.3CYP11B1, CYP11B2
6C21-steroid hormone biosynthetic processGO:000670010.3CYP11B1, CYP11B2
7regulation of systemic arterial blood pressure by renin-angiotensinGO:000308110.2ACE, AGTR1
8beta-amyloid metabolic processGO:005043510.2ACE, REN
9regulation of vasodilationGO:004231210.2ACE, AGTR1
10regulation of vasoconstrictionGO:001922910.1ACE, AGTR1
11glucocorticoid biosynthetic processGO:00067049.9CYP11B1, CYP17A1
12angiotensin maturationGO:00020039.9ACE, REN
13kidney developmentGO:00018229.4ACE, AGTR1, REN
14cellular response to peptide hormone stimulusGO:00713759.2CYP11B1, CYP11B2, MEN1
15sterol metabolic processGO:00161259.1CYP11B1, CYP11B2, CYP17A1
16regulation of blood pressureGO:00082178.4ACE, CYP11B1, NPPA, POMC, REN

Molecular functions related to Hyperaldosteronism according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1corticosterone 18-monooxygenase activityGO:004778310.4CYP11B1, CYP11B2
2steroid 11-beta-monooxygenase activityGO:000450710.4CYP11B1, CYP11B2
3oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygenGO:001670910.4CYP11B1, CYP11B2
4bradykinin receptor bindingGO:003171110.3ACE, AGTR1
5neuropeptide hormone activityGO:000518410.0NPPA, POMC
6heme bindingGO:00200379.4CYP11B1, CYP11B2, CYP17A1
7iron ion bindingGO:00055069.1CYP11B1, CYP11B2, CYP17A1

Sources for Hyperaldosteronism

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet