MCID: HYP604
MIFTS: 58

Hyperinsulinemic Hypoglycemia, Familial, 2 malady

Categories: Genetic diseases, Rare diseases, Endocrine diseases, Metabolic diseases

Aliases & Classifications for Hyperinsulinemic Hypoglycemia, Familial, 2

About this section

Aliases & Descriptions for Hyperinsulinemic Hypoglycemia, Familial, 2:

Name: Hyperinsulinemic Hypoglycemia, Familial, 2 52 12 68
Persistent Hyperinsulinemic Hypoglycemia of Infancy 23 48 24 70
Hyperinsulinemic Hypoglycemia 11 27 13 68
Congenital Hyperinsulinism 48 25 70 68
Familial Hyperinsulinism 23 48 24 27
Nesidioblastosis 11 50 39 68
Phhi 23 48 70
Persistent Hyperinsulinemia Hypoglycemia of Infancy 11 25
Islet Cell Hyperplasia 11 27
Hhf2 48 70
Fhi 23 24
Hyperinsulinemic Hypoglycemia Due to Kir6.2 Deficiency, Diazoxide-Resistant Focal Form 54
Autosomal Recessive Hyperinsulinemic Hypoglycemia Due to Kir6.2 Deficiency 54
Autosomal Dominant Hyperinsulinemic Hypoglycemia Due to Kir6.2 Deficiency 54
Diazoxide-Resistant Focal Hyperinsulinism Due to Kir6.2 Deficiency 54
Hyperinsulinemic Hypoglycemia Due to Focal Adenomatous Hyperplasia 48
Autosomal Recessive Hyperinsulinism Due to Kir6.2 Deficiency 54
 
Autosomal Dominant Hyperinsulinism Due to Kir6.2 Deficiency 54
Hyperinsulinism Familial with Pancreatic Nesidioblastosis 48
Dominant Katp Hyperinsulinism Due to Kir6.2 Deficiency 54
Hyperinsulinemia Hypoglycemia of Infancy 25
Hyperinsulinemic Hypoglycemia Familial 2 48
Persistent Hyperinsulinemic Hypoglycemia 25
Hypoglycemia Hyperinsulinemic of Infancy 48
Familial Hyperinsulinemic Hypoglycemia 2 70
Hyperinsulinemic Hypoglycemia Familial 48
Infancy Hyperinsulinemia Hypoglycemia 25
Nesidioblastosis of Pancreas 48
Hyperinsulinism Congenital 48
Neonatal Hyperinsulinism 25
Phhi Hypoglycemia 25
Hyperinsulinemia 24
Hyperinsulinism 68

Characteristics:

Orphanet epidemiological data:

54
autosomal dominant hyperinsulinemic hypoglycemia due to kir6.2 deficiency:
Inheritance: Autosomal dominant; Age of onset: Infancy,Neonatal
hyperinsulinemic hypoglycemia due to kir6.2 deficiency, diazoxide-resistant focal form:
Inheritance: Autosomal recessive; Age of onset: Infancy,Neonatal

HPO:

64
hyperinsulinemic hypoglycemia, familial, 2:
Inheritance: autosomal recessive inheritance

GeneReviews:

23
Penetrance: autosomal recessive fhi demonstrates nearly complete penetrance. some splice variants, particularly the abcc8 pathogenic variant common in the ashkenazi jewish population, present with markedly variable clinical severity; some homozygous individuals may be asymptomatic...


Classifications:



External Ids:

OMIM52 601820
Disease Ontology11 DOID:13317
ICD1030 E16.9
MeSH39 D046768
NCIt45 C4375
ICD10 via Orphanet31 E16.1
MedGen37 C2931833

Summaries for Hyperinsulinemic Hypoglycemia, Familial, 2

About this section
NIH Rare Diseases:48 Familial hyperinsulinism is an inherited condition that causes individuals to have abnormally high levels of insulin, which leads to frequent episodes of low blood sugar (hypoglycemia). In infants and young children, these episodes are characterized by a lack of energy (lethargy), irritability, and/or difficulty feeding. Repeated episodes of low blood sugar increase the risk for serious complications such as seizures, intellectual disability, breathing difficulties, and/or coma. Unlike typical episodes of hypoglycemia, which occur after periods without food (fasting), episodes of hypoglycemia in people with familial hyperinsulinism can also occur after eating or exercising. Mutations in at least seven genes have been found to cause this condition. It is often inherited in an autosomal recessive pattern or less commonly, an autosomal dominant pattern. Last updated: 12/21/2011

MalaCards based summary: Hyperinsulinemic Hypoglycemia, Familial, 2, also known as persistent hyperinsulinemic hypoglycemia of infancy, is related to hyperinsulinemic hypoglycemia, familial, 4 and obesity, and has symptoms including Array, Array and Array. An important gene associated with Hyperinsulinemic Hypoglycemia, Familial, 2 is KCNJ11 (Potassium Voltage-Gated Channel Subfamily J Member 11), and among its related pathways are Regulation of beta-cell development and Integration of energy metabolism. Affiliated tissues include brain, pancreas and liver, and related mouse phenotypes are liver/biliary system and endocrine/exocrine gland.

Disease Ontology:11 A carbohydrate metabolic disorder that involves low blood glucose resulting from an excess of insulin.

UniProtKB/Swiss-Prot:70 Familial hyperinsulinemic hypoglycemia 2: Most common cause of persistent hypoglycemia in infancy. Unless early and aggressive intervention is undertaken, brain damage from recurrent episodes of hypoglycemia may occur.

Description from OMIM:52 601820

GeneReviews for NBK1375

Related Diseases for Hyperinsulinemic Hypoglycemia, Familial, 2

About this section

Diseases in the Hyperinsulinemic Hypoglycemia, Familial, 2 family:

Hyperinsulinemic Hypoglycemia, Familial, 7 Hyperinsulinemic Hypoglycemia, Familial, 4
Hyperinsulinemic Hypoglycemia, Familial, 3 Hyperinsulinemic Hypoglycemia, Familial, 1
Hyperinsulinemic Hypoglycemia, Familial, 5

Diseases related to Hyperinsulinemic Hypoglycemia, Familial, 2 via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 142)
idRelated DiseaseScoreTop Affiliating Genes
1hyperinsulinemic hypoglycemia, familial, 433.4GCK, GLUD1, HADH, HADHA
2obesity29.4ABCC8, GCG, IGF2, INS, UCP2
3hyperinsulinemic hypoglycemia, familial, 712.4
4hyperinsulinemic hypoglycemia, familial, 112.4
5hyperinsulinemic hypoglycemia, familial, 512.4
6hyperinsulinemic hypoglycemia, familial, 312.4
7adult-onset non-insulinoma persistent hyperinsulinemic hypoglycemia12.0
8hyperinsulinism-hyperammonemia syndrome11.9
9insr-related hyperinsulinism11.2
10hypoglycemia11.0
11slc16a1-related hyperinsulinism11.0
12glud1-related hyperinsulinism11.0
13hyperinsulinism due to hnf4a deficiency11.0
14hyperinsulinism due to ucp2 deficiency11.0
15hyperinsulinism due to hnf1a deficiency11.0
16hyperinsulinism due to short chain 3-hydroxylacyl-coa dehydrogenase deficiency11.0
17mahvash disease11.0
18microcephaly, short stature, and impaired glucose metabolism11.0
19fuchs' heterochromic uveitis11.0
20fanconi renotubular syndrome 4, with maturity-onset diabetes of the young10.9
21retinal vasculitis10.9
22maturity-onset diabetes of the young, type 1310.7ABCC8, KCNJ11
23usher syndrome, type 1c10.7ABCC8, KCNJ11
24hemimegalencephaly10.7ABCC8, KCNJ11
25brachial plexus lesion10.6INS, SST
26focal facial dermal dysplasia10.6CHGA, SST
27petrous apex meningioma10.6INS, SST
28benign eccrine breast spiradenoma10.5IGF2, INS
29nephronophthisis 1910.5ABCC8, INS, KCNJ11
30repetitive motion disorders10.5INS, SST
31writing disorder10.5ABCC8, GCK, KCNJ11
32pearson syndrome10.5MEN1, SST
33neuronal ceroid lipofuscinosis10.5INS, SCT, SST
3410.4CHGA, SST
35image syndrome10.4GLUD1, INS
36bone marrow cancer10.4CHGA, IGF2, INS
37adrenal medulla cancer10.4MEN1, SST
38pancreatitis10.4
395q22 deletion syndrome10.4HADH, HADHA
40maturity-onset diabetes of the young, type 1010.4INS, SCT
41neonatal diabetes mellitus10.4GCK, INS, KCNJ11
42parathyroid transitional clear cell adenoma10.4CHGA, MEN1
43cutaneous leiomyosarcoma10.4GCG, IGF2
44malignant dermis tumor10.4GCG, IGF2
45adult ependymoblastoma10.3GCG, IGF2
46carcinoma of the vocal tract10.3CHGA, MEN1, SST
47migraine with aura10.3MEN1, SCT, SST
48toxic megacolon10.3ABCC8, GCK, INS, KCNJ11
49diaphanospondylodysostosis10.3ABCC8, GCK, INS, KCNJ11
50hematopoietic stem cell transplantation10.3CHGA, IGF2, MEN1

Graphical network of the top 20 diseases related to Hyperinsulinemic Hypoglycemia, Familial, 2:



Diseases related to hyperinsulinemic hypoglycemia, familial, 2

Symptoms & Phenotypes for Hyperinsulinemic Hypoglycemia, Familial, 2

About this section

Symptoms by clinical synopsis from OMIM:

601820

Clinical features from OMIM:

601820

Human phenotypes related to Hyperinsulinemic Hypoglycemia, Familial, 2:

 54 64 (show all 27)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 microcephaly54 Frequent (79-30%)
2 agitation54 Occasional (29-5%)
3 global developmental delay54 Occasional (29-5%)
4 hyperinsulinemic hypoglycemia64 54 Very frequent (99-80%) HP:0000825
5 hyperinsulinemia54 Very frequent (99-80%)
6 hyperhidrosis54 Very frequent (99-80%)
7 pallor54 Very frequent (99-80%)
8 seizures54 Occasional (29-5%)
9 lethargy54 Very frequent (99-80%)
10 coma54 Very frequent (99-80%)
11 hepatomegaly54 Frequent (79-30%)
12 large for gestational age64 54 Occasional (29-5%) HP:0001520
13 tachycardia54 Very frequent (99-80%)
14 hypoketotic hypoglycemia54 Very frequent (99-80%)
15 neonatal hypoglycemia54 Very frequent (99-80%)
16 vomiting54 Frequent (79-30%)
17 diarrhea54 Frequent (79-30%)
18 drowsiness54 Occasional (29-5%)
19 progressive neurologic deterioration54 Very frequent (99-80%)
20 decreased circulating cortisol level54 Occasional (29-5%)
21 abnormality of fatty-acid metabolism54 Very frequent (99-80%)
22 pancreatic islet-cell hyperplasia64 54 Very frequent (99-80%) HP:0004510
23 vitamin b1 deficiency54 Frequent (79-30%)
24 cognitive impairment54 Frequent (79-30%)
25 secondary growth hormone deficiency54 Occasional (29-5%)
26 abnormal brain fdg positron emission tomography54 Occasional (29-5%)
27 hypoglycemia64 HP:0001943

MGI Mouse Phenotypes related to Hyperinsulinemic Hypoglycemia, Familial, 2 according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053709.0GCK, HADHA, HNF4A, IGF2, INS, MEN1
2MP:00053797.5ABCC8, CHGA, GAST, GCK, GLUD1, HADH
3MP:00053787.5CHGA, GCK, GLUD1, HADH, HADHA, HNF4A
4MP:00107685.9CHGA, GAST, GCK, HADHA, HNF4A, IGF2
5MP:00053765.9ABCC8, CHGA, GAST, GCK, GLUD1, HADH

Drugs & Therapeutics for Hyperinsulinemic Hypoglycemia, Familial, 2

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Drugs for Hyperinsulinemic Hypoglycemia, Familial, 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 112)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
SomatostatinapprovedPhase 422938916-34-6, 51110-01-153481605
Synonyms:
growth hormone-inhibiting hormone (GHIH)
 
somatotropin release-inhibiting factor (SRIF)
somatotropin release-inhibiting hormone
2
Octreotideapproved, investigationalPhase 4, Phase 221383150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
 
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate
3
lanreotideapprovedPhase 482108736-35-2
Synonyms:
Lanreotide
 
Lanreotide acetate
Somatuline Depot
4
NifedipineapprovedPhase 411221829-25-44485
Synonyms:
101539-70-2
101554-38-5
21829-25-4
4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester
5-22-04-00268 (Beilstein Handbook Reference)
60299-11-8 (mono-hydrochloride)
AC-11618
AC1L1I9V
AC1Q4254
AKOS002942507
ARONIS24171
AWD Pharma Brand of Nifedipine
Adalat
Adalat (TN)
Adalat 10
Adalat 20
Adalat 5
Adalat CC
Adalat CR
Adalat Crono
Adalat FT
Adalat Ft
Adalat GITS
Adalat GITS 30
Adalat Gits
Adalat Gits 30
Adalat LA
Adalat LP
Adalat Oros
Adalat PA
Adalat Retard
Adalat XL
Adalate
Adalate LP
Adapine
Adapress
Adcock Ingram Brand of Nifedipine
Adipine XL
Afeditab
Afeditab CR
Afeditab CR (TN)
Alat
Aldipin
Alfadal
Alonix
Alonix S
Alpha-Nifedipine Retard
Angipec
Anifed
Anpine
Apo-Nifed
Aprical
Aprical long
BAY 1040
BAY A 1040
BAY-a 1040
BAYa1040
BCBcMAP01_000046
BIDD:GT0442
BIDD:PXR0034
BIM-0050796.0001
BPBio1_000271
BRN 0497773
BSPBio_000245
BSPBio_001391
BSPBio_002071
Bay-1040
Bay-a-1040
Bay1040
Bayer Brand of Nifedipine
Bio-0733
Bio1_000112
Bio1_000601
Bio1_001090
Bio2_000111
Bio2_000591
Bonacid
C07266
C17H18N2O6
CAS-21829-25-4
CBiol_001826
CCRIS 6074
CHEBI:7565
CHEMBL193
CID4485
CPD000058291
Calcibloc
Calcigard
Calcilat
Camont
Cardifen
Cardilat
Cardionorm
Chronadalate
Chronadalate LP
Chronadalate Lp
Citilat
Coracten
Coracten XL
Coral
Cordafen
Cordaflex
Cordalat
Cordicant
Cordilan
Cordipin
Cordipine
Corinfar
Corotrend
Corynphar
D00437
D009543
DB01115
Depin
Dignokonstant
Dilafed
Dilcor
Dipinkor
DivK1c_000313
Duranifin
EINECS 244-598-3
EU-0100819
Ecodipi
Ecodipin
Ecodipin E
Emaberin
Fedcor
Fedcor Retard
Fenamon
Fenamon SR
Fenamon Sr
Fenigidin
Fenihidin
Fenihidine
Fortipine LA
Glopir
HMS1361F13
HMS1568M07
HMS1791F13
HMS1920P19
HMS1989F13
HMS2051O03
HMS2089H11
HMS2091H20
 
HMS500P15
Hadipin
Hexadilat
I06-0051
I06-1286
IDI1_000313
IDI1_033861
Infedipin
Introcar
KB-1712P
KBio1_000313
KBio2_000111
KBio2_001459
KBio2_002400
KBio2_002679
KBio2_004027
KBio2_004968
KBio2_005247
KBio2_006595
KBio2_007536
KBio3_000221
KBio3_000222
KBio3_001571
KBio3_002879
KBioGR_000111
KBioGR_000627
KBioGR_002400
KBioSS_000111
KBioSS_001459
KBioSS_002405
KRKA Brand of Nifedipine
Kordafen
Korinfar
L001054
LS-1012
Lopac-N-7634
Lopac0_000819
MLS000028521
MLS000758222
MLS001148146
MLS001401371
Macorel
Megalat
MolPort-000-787-707
MolPort-006-822-492
Monohydrochloride, Nifedipine
Myogard
N 7634
N0528
N1fedilat
N7634_SIGMA
NCGC00015748-01
NCGC00015748-02
NCGC00015748-03
NCGC00015748-06
NCGC00015748-13
NCGC00024983-01
NCGC00024983-02
NCGC00024983-03
NCGC00024983-04
NCGC00024983-05
NCGC00024983-06
NCGC00024983-07
NCGC00024983-08
NCGC00091707-01
NINDS_000313
Nedipin
Nicardia
Nifangin
Nifar
Nifdemin
Nifebene
Nifecard
Nifecor
Nifedepat
Nifediac
Nifedical
Nifedical XL
Nifedicor
Nifedin
Nifedine
Nifedipine
Nifedipine (JP15/USP/INN)
Nifedipine Bayer Brand
Nifedipine GTIS
Nifedipine KRKA Brand
Nifedipine Monohydrochloride
Nifedipine Orion Brand
Nifedipine Pfizer Brand
Nifedipine Retard
Nifedipine [USAN:BAN:INN:JAN]
Nifedipine-GTIS
Nifedipino
Nifedipino [INN-Spanish]
Nifedipinum
Nifedipinum [INN-Latin]
Nifedipres
Nifedirex LP
Nifelan
Nifelat
Nifelat Q
Nifelate
Nifensar XL
Nificard
Nifidine
Nifipen
Niphedipine
Oprea1_788617
Orion Brand of Nifedipine
Orix
Oxcord
Pfizer Brand of Nifedipine
Pidilat
Prestwick0_000063
Prestwick1_000063
Prestwick2_000063
Prestwick3_000063
Prestwick_357
Procardia
Procardia (TN)
Procardia XL
S1808_Selleck
SAM001246963
SMR000058291
SPBio_001016
SPBio_002166
SPECTRUM1500431
STK735567
Sepamit
Slofedipine XL
Spectrum2_001058
Spectrum3_000516
Spectrum4_000074
Spectrum5_001278
Spectrum_000979
Tensipine MR
Tibricol
Tocris-1075
UNII-I9ZF7L6G2L
Vascard
ZINC19594578
Zenusin
cMAP_000042
nchembio.95-comp13
nifedipine
5
CilnidipineapprovedPhase 48132203-70-45282138
Synonyms:
(+-)-(E)-Cinnamyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methoxyethyl (2E)-3-phenyl-2-propenyl ester
132203-70-4
2-methoxyethyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
AC-270
AC1NQZJB
Atelec
Atelec (TN)
BRD-A07875874-001-01-6
Bio-0164
C1493_SIGMA
C27H28N2O7
CHEBI:31399
CHEBI:438069
CHEMBL452076
CID5282138
 
Cilnidipine (JAN/INN)
Cilnidipine [INN]
Cinaldipine
Cinalong
D01173
FRC 8653
FRC-8653
HMS2089J07
I06-0491
LS-131293
MolPort-003-845-950
NCGC00162150-01
NCGC00162150-02
NCGC00162150-03
S1293_Selleck
STK623341
Siscard
cilnidipine
6
MentholapprovedPhase 423532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
7
BenzocaineapprovedPhase 4, Phase 1, Phase 218921994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
8
MetforminapprovedPhase 41746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
9
Pioglitazoneapproved, investigationalPhase 4435111025-46-84829
Synonyms:
(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione
(+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione
105355-27-9
111025-46-8
198077-89-3
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI)
5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione
5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione
5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
AB1004597
AC-1021
AC1L1J1Q
AD 4833
AD-4833
Actos
Actos (TN)
Actost
BRD-A48430263-003-02-4
BSPBio_002723
C07675
C19H20N2O3S
CHEBI:8228
CHEMBL595
CID4829
D08378
DB01132
Duetact
Glustin
HMS2089H14
HS-0047
 
HSDB 7322
I06-0089
KBio2_002103
KBio2_004671
KBio2_007239
KBio3_001943
KBioGR_001619
KBioSS_002103
LS-151327
MolPort-002-508-211
NCGC00163128-01
NCGC00163128-02
Pioglitazona
Pioglitazona [INN-Spanish]
Pioglitazone
Pioglitazone HCl
Pioglitazone Hydrochloride
Pioglitazone [BAN:INN]
Pioglitazone [Ban:Inn]
Pioglitazone [INN:BAN]
Pioglitazonum
Pioglitazonum [INN-Latin]
SPBio_001897
Spectrum2_001679
Spectrum3_001002
Spectrum4_001130
Spectrum5_001480
Spectrum5_002067
Spectrum_001623
U 72107
U 72107A
U-72107
U72,107A
UNII-X4OV71U42S
Zactos
nchembio790-comp10
pioglitazone (INN)
pioglitazone HCl
10
Bosentanapproved, investigationalPhase 4103147536-97-8104865
Synonyms:
-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
147536-97-8
174227-18-0
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
4-t-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
AC-148
AC1L2XN2
Actelion
Bosentan
Bosentan (INN)
Bosentan [USAN:INN:BAN]
Bosentan hydrate
C27H29N5O6S
CHEBI:51450
CHEMBL957
CID104865
D07538
DB00559
 
EN002863
HMS2090N14
I06-1873
KS-5062
L001086
LS-31532
MolPort-003-845-300
NCGC00167440-01
PDSP1_001731
PDSP2_001714
Ro 47-0203
Ro 47-0203/039
Ro-47-0203
Ro-47-0203/029
Ro-47-0203/039
TL8001039
Tracleer
UNII-XUL93R30K2
bosentan
bosentanum
bosentán
p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
p-tert-Butyl-N-[6-(2-hydroxyethoxy)
11tannic acidapproved, NutraceuticalPhase 4, Phase 1, Phase 21892
12Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 1, Phase 2, Early Phase 112767
13AngiopeptinPhase 482
14Antihypertensive AgentsPhase 4, Phase 2, Phase 34095
15Hormone AntagonistsPhase 4, Phase 1, Phase 2, Early Phase 112778
16Hypoglycemic AgentsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 15733
17HormonesPhase 4, Phase 1, Phase 2, Early Phase 113979
18Vasodilator AgentsPhase 4, Phase 2, Phase 33438
19insulinPhase 4, Phase 24524
20Insulin, Globin ZincPhase 4, Phase 24523
21Calcium, DietaryPhase 45525
22calcium channel blockersPhase 41940
23Tocolytic AgentsPhase 4708
24Endothelin Receptor AntagonistsPhase 4215
25
DiazoxideapprovedPhase 2, Phase 322364-98-73019
Synonyms:
2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
364-98-7
7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]
7-chloro-3-methyl-4H-1
AC1L1EZN
Aroglycem
BPBio1_000016
BRD-K73109821-001-05-2
BSPBio_000014
BSPBio_001307
BSPBio_002290
Bio1_000036
Bio1_000525
Bio1_001014
Bio2_000027
Bio2_000507
C06949
C8H7ClN2O2S
CAS-364-98-7
CBiol_001750
CHEBI:4495
CHEMBL181
CID3019
CPD000058392
D 9035
D00294
D003981
D9035_SIGMA
DB01119
Diazossido
Diazossido [DCIT]
Diazossido [Italian]
Diazoxide
Diazoxide (JAN/USP/INN)
Diazoxide [USAN:INN:BAN]
Diazoxido
Diazoxido [INN-Spanish]
Diazoxidum
Diazoxidum [INN-Latin]
Dizoxide
EINECS 206-668-1
EU-0100404
Eudemine
HMS1361B09
HMS1568A16
HMS1791B09
HMS1922L22
HMS1989B09
HMS2051P20
HMS2089L04
HMS2093N12
Hyperstat
Hyperstat (TN)
Hypertonalum
I06-2041
 
IDI1_033777
KBio2_000027
KBio2_002595
KBio2_005163
KBio3_000053
KBio3_000054
KBio3_001510
KBioGR_000027
KBioGR_001776
KBioSS_000027
LS-40410
Lopac-D-9035
Lopac0_000404
MLS000028459
MLS001076071
MolPort-003-666-772
MolPort-003-941-186
Mutabase
NCGC00015380-01
NCGC00015380-02
NCGC00015380-03
NCGC00015380-05
NCGC00015380-12
NCGC00024907-01
NCGC00024907-02
NCGC00024907-03
NCGC00024907-04
NCGC00024907-05
NCGC00024907-06
NCGC00024907-07
NCGC00024907-08
NSC 64198
NSC 76130
NSC-64198
NSC64198
NSC76130
Prestwick0_000087
Prestwick1_000087
Prestwick2_000087
Prestwick3_000087
Prestwick_163
Proglicem
Proglycem
SAM001246872
SMR000058392
SPBio_001953
SPECTRUM2300206
SRG 95213
SRG-95213
Sch 6783
Sch-6783
Spectrum3_000735
Spectrum4_001248
Tocris-0964
UNII-O5CB12L4FN
VU0239714-6
ZINC03872277
diazoxide
nchembio.150-comp49
nchembio.476-comp10
26
NelfinavirapprovedPhase 3137159989-64-764143
Synonyms:
(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide
(3S-(2(2S*,3S*),3alpha,4abeta,8abeta))-N-(1,1-Dimethylethyl)decahydro-2-(2-hydroxy-3-((3-hydroxy-2-methylbenzoyl)amino)-4-(phenylthio)butyl)-3-isoquinolinecarboxamide
159989-64-7
159989-65-8 (monomethane sulfonate (salt))
1UN
1ohr
2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE
AC-20032
AC1L20J6
AG 1343
AG1343
AG1343 (*Mesylate salt*)
AG1346
AKOS000280862
BIDD:GT0395
BIDD:PXR0143
C07257
C32H45N3O4S
CHEMBL584
CID64143
D08259
DB00220
LS-85417
MLS001195634
 
MLS001304729
Met-SDF-1.beta. & Nelfinavir
Met-Stromal Cell-derived Factor-1.beta. (Human) & Nelfinavir
MolPort-000-883-833
MolPort-002-885-844
NCGC00090782-03
NCGC00090782-04
NELFINAVIR MESYLATE AG1343
NFV
NLF
NSC722664
NSC747167
Nelfinavir
Nelfinavir (INN)
Nelfinavir Monomethane Sulfonate
Nelfinavir [BAN:INN]
Nelfinavir [INN:BAN]
Nelfinavir mesylate
SMR000596515
UNII-HO3OGH5D7I
VRX496
Viracept
Viracept (TM)(*Mesylate salt*)
Viracept (TN)
ag1343
nelfinavir
27
Lamivudineapproved, investigationalPhase 3613134678-17-460825
Synonyms:
(+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(+/-)-3TC
(+/-)-BCH-189
(+/-)-SddC
(-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-2'-Deoxy-3'-thiacytidine
(-)-BCH 189
(-)-BCH-189
(-)-SddC
(-)-beta-L-2',3'-Dideoxy-3'-thiacytidine
(-)NGPB-21
(2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
.beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To
134678-17-4
2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA)
3'-Thia-2',3'-dideoxycytidine
3TC
3TC & GNA
3TC & SST
3TC (AIDS INITIATIVE) (AIDS INITIATIVE)
3TC and NV-01
3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine
4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
480434-79-5
AC-1416
AC1L1TZZ
AC1Q6C34
BCH 189
BCH-189
BCH-790
BCH189
BIDD:GT0033
Bio-0652
C07065
C8H11N3O3S
CCRIS 9274
CHEBI:133986
CHEMBL141
CID60825
CPD000466319
D00353
D019259
 
DB00709
DRG-0126
DTHC
Epivir
Epivir (TN)
Epivir(TM)
Epivir-HBV
Epzicom
FT-0082667
GG-714
GR 109714X
GR-109714X
GR109714X
HHA & 3TC
HHA & Lamivudine
HMS2051D21
HSDB 7155
Hepitec
Heptivir
Heptodin
Heptovir
L0217
LMV
LS-2107
Lamivir
Lamivudin
Lamivudina
Lamivudine
Lamivudine & GNA
Lamivudine (JAN/USP/INN)
Lamivudine [USAN:BAN:INN]
Lamivudine [USAN:INN:BAN]
Lamivudine [Usan:Ban:Inn]
Lamivudine, (2S-cis)-Isomer
Lamivudinum
MLS000759424
MLS001424097
MolPort-002-507-347
NCGC00159341-03
NCGC00159341-04
NSC620753
S1706_Selleck
SAM001246582
SAM002589994
SMR000466319
STK801940
UNII-2T8Q726O95
ZINC00012346
Zeffix
Zefix
beta-L-2',3'-Dideoxy-3'-thiacytidine
beta-L-3'-Thia-2',3'-dideoxycytidine
lamivudine
28
ZidovudineapprovedPhase 349430516-87-135370
Synonyms:
-Azido-3&prime
-deoxythymidine
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine
3&prime
3' Azido 2',3' Dideoxythymidine
3' Azido 3' deoxythymidine
3'-Azido-2',3'-Dideoxythymidine
3'-Azido-3'-deoxythymidine
3'-Azido-3'-deoxythymidine & Concanavalin A
3'-Azido-3'-deoxythymidine & Erythropoietin
3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19
3'-Azido-3'-deoxythymidine & Interleukin-1
3'-Azido-3'-deoxythymidine & Interleukin-2
3'-Azido-3'-deoxythymidine & Interleukin-6
3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6
3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon
3'-Azido-3'-deoxythymidine & Sho-Saiko-To
3'-Azido-3'-deoxythymidine (AIDS)
3'-Azido-3'deoxythymidine & Interferon .alpha.
3'-Azidothymidine
3'-Deoxy-3'-azidothymidine
3'-azido-3'-deoxythymidine, AZT
3-Azido-3-deoxythymidine
30516-87-1
399024-19-2
A2169_SIGMA
AC1L1TKL
AC1Q2OEK
AZT
AZT & CD4(178)-PE 40
AZT & Colony-stimulating factor 2
AZT & Concanavalin A (ConA)
AZT & EPO
AZT & GM-CSF
AZT & HPA
AZT & IFN.alpha.
AZT & IL-1
AZT & IL-2
AZT & IL-6
AZT & Interferon-.alpha.-2
AZT & Li & EPO
AZT & Li & GM-CSF
AZT & Li & IL-1
AZT & Li & IL-6
AZT & Lymphoblastoid Interferon
AZT & NP (from PHCA or HSA)
AZT & PM-19
AZT & SST
AZT & rIFN.alpha.2
AZT & rsCD4 & rIFN.alpha.A
AZT & rsT4
AZT & sCD4
AZT & srCD4
AZT (Antiviral)
AZT Antiviral
AZT TRANSPLACENTAL CARCINOGENESIS STUDY
AZT+PRO 140
AZT, Antiviral
Antiviral AZT
Apo-Zidovudine
Azidothymidine
Aztec
BB_NC-1012
BPBio1_000403
BRD-K72903603-001-04-6
BSPBio_000365
BSPBio_003153
BW A509U
BW-A 509U
BW-A-509U
BW-A509U
BWA 509U
BWA-509U
BWA509U
C07210
CCRIS 105
CHEBI:10110
CHEBI:127307
CHEMBL129
CID35370
 
CPD000058351
Compound S
Cpd S
D00413
D015215
DB00495
DRG-0004
DS-4152 & AZT
DivK1c_000524
HMS1921J20
HMS2090G11
HMS2092D06
HMS501K06
HSDB 6515
IDI1_000524
Interferon AD + 3'-azido-3'-deoxythymidine
Intron A & AZT
K7 [P Ti2 W10 O40]
KBio1_000524
KBio2_001828
KBio2_004396
KBio2_006964
KBio3_002653
KBioGR_000703
KBioSS_001828
LS-1159
Liposomal AZT-SN-1
Liposomal AZT-SN-3
MLS000028548
MLS001055351
MLS001076358
MLS002153202
MLS002222249
Met-SDF-1.beta. & AZT
Met-SDF-1.beta. & Zidovudine
MolPort-002-507-286
NCGC00023945-03
NCGC00023945-04
NCGC00023945-05
NCGC00023945-08
NCGC00178237-01
NCGC00178237-02
NINDS_000524
NSC 602670
Novo-Azt
PC-SOD+AZT
Prestwick3_000333
Propolis+AZT
Racemic Liposomal AZT
Retrovir
Retrovir (TN)
Retrovir(TM)
SAM002548971
SMR000058351
SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SPBio_000834
SPECTRUM1502109
STK801891
Spectrum2_000927
Spectrum3_001507
Spectrum4_000332
Spectrum5_001101
Spectrum_001348
UNII-4B9XT59T7S
ZDV
ZIDOVUDINE [AZT]
ZINC03779042
ZVD
Zidovudin
Zidovudina
Zidovudina [Spanish]
Zidovudine (JAN/USP/INN)
Zidovudine EP III
Zidovudine [USAN:INN:BAN:JAN]
Zidovudine+PRO 140
Zidovudinum
Zidovudinum [Latin]
antiviral
azidodeoxythymidine
rIFN-beta seron & AZT
racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
zidovudin
zidovudine
29
NevirapineapprovedPhase 3222129618-40-24463
Synonyms:
11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE
11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-6-one
11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-6-one & PRO 140 (Anti-CCR5 monoclonal antibody)
11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one
129618-40-2
1vrt
2hny
AC-643
AC1L1I81
BI RG 587
BI-RG-587
BI-RG-587 & CD4-IgG
BIDD:GT0326
BIRG 0587
BIRG 587
BIRG-0587
BIRG-587
BIRG587
Bio-0789
C07263
C15H14N4O
CHEBI:44659
CHEMBL57
CID4463
CPD000048458
Cahill May Roberts Brand of Nevirapine
D00435
D019829
DB00238
DB08311
 
HMS2051J09
HSDB 7164
I02-0310
LS-2289
MLS000084585
MLS000759409
MLS001055309
MLS001201730
MolPort-002-507-817
N11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e]-[1,4]diazepin-6-one & CD4-immunoadhesin
NCGC00065890-02
NEV
NON-NUCLEOSIDE RT INHIBITOR NEVIRAPINE
NSC 641530
NSC641530
NVP
Nevirapine
Nevirapine & CD4-IgG
Nevirapine & PRO 140
Nevirapine (JAN/USP/INN)
Nevirapine [USAN:INN]
Promeco Brand of Nevirapine
S1742_Selleck
SAM001246551
SMR000048458
STK580320
UNII-99DK7FVK1H
Viramune
Viramune (TN)
Viramune(TM)
Viramune, BI-RG 587, Nevirapine
ZINC00004778
nevirapine
30
protease inhibitorsPhase 35320
Synonyms:
 
protease inhibitors
31Reverse Transcriptase InhibitorsPhase 31880
32Lamivudine, zidovudine drug combinationPhase 3111
33Nucleic Acid Synthesis InhibitorsPhase 34855
34Anti-HIV AgentsPhase 33100
35AntimetabolitesPhase 311774
36Anti-Infective AgentsPhase 3, Phase 1, Phase 221402
37Anti-Retroviral AgentsPhase 33232
38Antiviral AgentsPhase 39732
39Cytochrome P-450 CYP3A InducersPhase 31101
40HIV Protease InhibitorsPhase 35319
41
DopamineapprovedPhase 2, Phase 1375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
42
Sirolimusapproved, investigationalPhase 1, Phase 2189653123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
43
Exenatideapproved, investigationalPhase 1, Phase 2, Early Phase 1289141758-74-915991534
Synonyms:
141732-76-5
141758-74-9
286014-72-0
335149-21-8
AC 2993
AC 2993 LAR
AC 2993A
AC-2993
AC002993
AC2993
AC2993a
Bydureon
Byetta
 
C074031
CHEBI:490990
CHEMBL414357
Ex4 peptide
Exenatide
Exenatide Synthetic
Exenatide synthetic
Exendin 4
Exendin 4 (Heloderma suspectum)
Exendin-4
Extendin-4
LY2148568
Synthetic exendin-4
UNII-9P1872D4OL
44
EverolimusapprovedPhase 1, Phase 21896159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
45
Miconazoleapproved, investigational, vet_approvedPhase 1, Phase 2362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
46
PancrelipaseapprovedPhase 293553608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
PA
 
Pancreatic alpha-amylase precursor
Pancrelipase (amylase
lipase
protease)
47Dopamine AgentsPhase 2, Phase 13759
48glucagonPhase 1, Phase 2, Early Phase 1462
49Antineoplastic Agents, HormonalPhase 25407
50Gastrointestinal AgentsPhase 2, Early Phase 18109

Interventional clinical trials:

(show top 50)    (show all 85)
idNameStatusNCT IDPhase
1Lanreotide Autogel Treatment of Patients With Congenital Hyperinsulinism of InfancyUnknown statusNCT01070758Phase 4
2Diet, Obesity and Genes (DiOGenes)Unknown statusNCT00390637Phase 4
3Effect of Magnesium Administration in Subjects With Family History of Diabetes or Metabolic SyndromeCompletedNCT01181830Phase 4
4A Study of the Effects of Exercise Intensity on Insulin Sensitivity in Overweight YouthCompletedNCT00755547Phase 4
5The Effects of Cilnidipine on Metabolic Syndrome ImprovementCompletedNCT00325936Phase 4
6Insulin Resistance and Mild Cognitive Impairment (IRMCI) StudyRecruitingNCT02409238Phase 4
7Insulin Resistance in Pulmonary Arterial HypertensionTerminatedNCT00825266Phase 4
8Diazoxide In the Management Of Hypoglycemic NeonatesUnknown statusNCT00994149Phase 2, Phase 3
9Evaluating the Effectiveness of a Community Exercise Program to Reduce the Risk of Metabolic Syndrome Among Black AmericansCompletedNCT00783445Phase 3
10Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During PregnancyCompletedNCT00017719Phase 3
11Effects of Leptin Replacement in ChildrenUnknown statusNCT00659828Phase 2
12Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital HyperinsulinismCompletedNCT00571324Phase 1, Phase 2
13Sandostatine® LP and HyperinsulinismCompletedNCT00987168Phase 2
14The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese ChildrenCompletedNCT00108901Phase 2
15Study of Aramchol in Patients With Fatty Liver Disease or Nonalcoholic SteatohepatitisCompletedNCT01094158Phase 2
16A Single-Dose Open-Label Study of XOMA 358 in Subjects With Congenital HyperinsulinismRecruitingNCT02604485Phase 2
17CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital HyperinsulinismRecruitingNCT02937558Phase 2
18Effect of Exendin-(9-39) On Glucose Requirements To Maintain EuglycemiaRecruitingNCT00835328Phase 1, Phase 2
19Effect of Exendin-(9-39) on Fasting Adaptation and Protein SensitivityRecruitingNCT00897676Phase 1, Phase 2
20Sirolimus for the Treatment of HyperinsulinismRecruitingNCT02524639Phase 1, Phase 2
21Phase II Safety and Efficacy Study of F-DOPA PET/CT in Children With Hyperinsulinemic HypoglycemiaActive, not recruitingNCT01468454Phase 2
22Utility of [F-18] fluoroDOPA for Neonatal HyperinsulinismActive, not recruitingNCT00674440Phase 2
23Effect of Gelofusine on GLP1-receptor ImagingActive, not recruitingNCT02541734Phase 1, Phase 2
24Health of Young European Families and Fish ConsumptionUnknown statusNCT00315770Phase 1
25Metabolic Syndrome in Young Patients With Acute Lymphoblastic Leukemia in RemissionUnknown statusNCT00801346Phase 1
26Fluorodopa F 18 in Congenital HyperinsulinismRecruitingNCT02021604Phase 1
27Long Term Glucose Metabolism in Conservatively Treated Patients With Congenital HyperinsulinismUnknown statusNCT01819584
28Utilizing a Promotora Model for Rural Adult Hispanics Diagnosed With Metabolic Syndrome: A Clinical TrialUnknown statusNCT01839864
29Metabolic Syndrome as Modifiable Risk Factor for Breast CancerUnknown statusNCT01172886
30Adipokines as Predictors of the Metabolic Syndrome in ALL SurvivorsUnknown statusNCT00566566
31Ginsenoside Improve Metabolic SyndromeUnknown statusNCT02034136
32Role of the Stress in the Development of the Metabolic SyndromeUnknown statusNCT01538082
33Towards Individualized Surgery in Non-focal Congenital HyperinsulinismCompletedNCT02108730
34Physical Activity, Insulin Resistance and Function of Fat Tissue in the Offspring of Patients With Type 2 DiabetesCompletedNCT00268541
35Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.CompletedNCT00720889
36Effects of a Comprehensive Weight Management Program on Obese Adolescents and ChildrenCompletedNCT00409422
37A Family Based Intervention to Reduce the Risk of Type 2 Diabetes in ChildrenCompletedNCT01146314
38Effects of FXR Activation on Hepatic Lipid and Glucose MetabolismCompletedNCT00465751Early Phase 1
39Insulin Resistance and Breast CancerCompletedNCT00304941
40Endothelial Function in Young Hispanic Adults at Risk for Type 2 DiabetesCompletedNCT01926938
41Sleep Loss and Energy Metabolism in People With Family History of Type 2 Diabetes.CompletedNCT00724087
42Sleep Loss and Glucose Metabolism in People With Family History of Type 2 Diabetes.CompletedNCT00721019
43Does Class of Dietary Fat Affect Insulin Resistance?CompletedNCT01541592
44Family-Centered Diabetes Project - Sharing WisdomCompletedNCT00438126
45Inflammatory Profiles of Children at High Risk for AtherosclerosisCompletedNCT00115232
46Family Linkage Study of Obstructive Sleep Apnea (OSA) in IcelandCompletedNCT00083798
47Insulin Resistance and Insulin SecretionCompletedNCT00073294
48Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Antipsychotic Drugs in Healthy HumansCompletedNCT00625170
49Phospholipid and Sphingolipid Composition of High-density Lipoproteins (HDL) in Obese Non-diabetic Patients With Metabolic SyndromeCompletedNCT02851602
50The Flamenco (Fitness League Against MENopause COsts) ProjectCompletedNCT02358109

Search NIH Clinical Center for Hyperinsulinemic Hypoglycemia, Familial, 2


Cochrane evidence based reviews: nesidioblastosis

Genetic Tests for Hyperinsulinemic Hypoglycemia, Familial, 2

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Genetic tests related to Hyperinsulinemic Hypoglycemia, Familial, 2:

id Genetic test Affiliating Genes
1 Islet Cell Hyperplasia27
2 Familial Hyperinsulinism27 24 UCP2
3 Hyperinsulinemic Hypoglycemia27

Anatomical Context for Hyperinsulinemic Hypoglycemia, Familial, 2

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MalaCards organs/tissues related to Hyperinsulinemic Hypoglycemia, Familial, 2:

36
Brain, Pancreas, Liver, Pancreatic islet, Endothelial, Testes, Heart

Publications for Hyperinsulinemic Hypoglycemia, Familial, 2

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Variations for Hyperinsulinemic Hypoglycemia, Familial, 2

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UniProtKB/Swiss-Prot genetic disease variations for Hyperinsulinemic Hypoglycemia, Familial, 2:

70 (show all 17)
id Symbol AA change Variation ID SNP ID
1KCNJ11p.Leu147ProVAR_001557rs28936678
2KCNJ11p.Lys67AsnVAR_026506
3KCNJ11p.Trp91ArgVAR_026507
4KCNJ11p.Pro254LeuVAR_026513
5KCNJ11p.Arg34HisVAR_031329
6KCNJ11p.Gly40AspVAR_031330
7KCNJ11p.Phe55LeuVAR_031335
8KCNJ11p.Ala101AspVAR_031336
9KCNJ11p.Ser116ProVAR_031337
10KCNJ11p.Gly134AlaVAR_031338
11KCNJ11p.Arg136LeuVAR_031339
12KCNJ11p.His259ArgVAR_031345
13KCNJ11p.Pro266LeuVAR_031346
14KCNJ11p.Arg301HisVAR_031347
15KCNJ11p.Gly156ArgVAR_073683
16KCNJ11p.Asp204GluVAR_073685
17KCNJ11p.Glu282LysVAR_073687

Clinvar genetic disease variations for Hyperinsulinemic Hypoglycemia, Familial, 2:

5 (show all 39)
id Gene Variation Type Significance SNP ID Assembly Location
1HNF4ANM_000457.4(HNF4A): c.253C> T (p.Arg85Trp)SNVPathogenicrs587777732GRCh38Chr 20, 44406195: 44406195
2ABCC8NM_000352.4(ABCC8): c.3509delT (p.Leu1170Argfs)deletionPathogenicrs587783169GRCh38Chr 11, 17404560: 17404560
3ABCC8NM_001287174.1(ABCC8): c.2147G> T (p.Gly716Val)SNVPathogenicrs72559723GRCh37Chr 11, 17448671: 17448671
4ABCC8NM_001287174.1(ABCC8): c.2800C> T (p.Arg934Ter)SNVLikely pathogenic, Pathogenicrs570388861GRCh37Chr 11, 17429962: 17429962
5ABCC8NM_001287174.1(ABCC8): c.2509C> T (p.Arg837Ter)SNVLikely pathogenic, Pathogenicrs72559722GRCh38Chr 11, 17412716: 17412716
6ABCC8NM_001287174.1(ABCC8): c.4163_4165delTCT (p.Phe1388del)deletionPathogenicrs151344624GRCh37Chr 11, 17417435: 17417437
7ABCC8NM_000352.4(ABCC8): c.2117-1G> ASNVPathogenicrs797045207GRCh37Chr 11, 17448702: 17448702
8ABCC8NM_000352.4(ABCC8): c.331G> A (p.Gly111Arg)SNVLikely pathogenic, Pathogenicrs761749884GRCh37Chr 11, 17491729: 17491729
9ABCC8NM_000352.4(ABCC8): c.4119+1G> ASNVPathogenicrs797045211GRCh38Chr 11, 17396915: 17396915
10ABCC8NM_000352.4(ABCC8): c.563A> G (p.Asn188Ser)SNVLikely pathogenic, Pathogenicrs797045213GRCh38Chr 11, 17463454: 17463454
11KCNJ11NM_000525.3(KCNJ11): c.79C> T (p.Arg27Cys)SNVLikely pathogenicrs752507753GRCh37Chr 11, 17409560: 17409560
12KCNJ11NM_000525.3(KCNJ11): c.866G> C (p.Gly289Ala)SNVLikely pathogenicrs797045637GRCh37Chr 11, 17408773: 17408773
13KCNJ11NM_000525.3(KCNJ11): c.866G> T (p.Gly289Val)SNVLikely pathogenicrs797045637GRCh38Chr 11, 17387226: 17387226
14KCNJ11NM_000525.3(KCNJ11): c.881C> T (p.Thr294Met)SNVPathogenicrs780957825GRCh38Chr 11, 17387211: 17387211
15KCNJ11NM_000525.3(KCNJ11): c.154C> T (p.Gln52Ter)SNVLikely pathogenicrs879253757GRCh38Chr 11, 17387938: 17387938
16ABCC8NM_000352.4(ABCC8): c.4306C> T (p.Arg1436Ter)SNVLikely pathogenic, Pathogenicrs193922402GRCh37Chr 11, 17417158: 17417158
17ABCC8ABCC8, EX13DELdeletionPathogenicChr na, -1: -1
18ABCC8ABCC8, 1-BP DUP, 512TduplicationPathogenicChr na, -1: -1
19ABCC8ABCC8, IVS8, A-G, -1013SNVPathogenicChr na, -1: -1
20KCNJ11NM_000525.3(KCNJ11): c.440T> C (p.Leu147Pro)SNVPathogenicrs28936678GRCh37Chr 11, 17409199: 17409199
21KCNJ11NM_000525.3(KCNJ11): c.36C> A (p.Tyr12Ter)SNVPathogenicrs104894236GRCh37Chr 11, 17409603: 17409603
22KCNJ11NM_000525.3(KCNJ11): c.-134G> TSNVPathogenicrs387906398GRCh37Chr 11, 17409772: 17409772
23KCNJ11NM_000525.3(KCNJ11): c.761C> T (p.Pro254Leu)SNVPathogenicrs104894237GRCh37Chr 11, 17408878: 17408878
24KCNJ11NM_000525.3(KCNJ11): c.776A> G (p.His259Arg)SNVPathogenicrs104894248GRCh37Chr 11, 17408863: 17408863
25KCNJ11NM_000525.3(KCNJ11): c.902G> A (p.Arg301His)SNVPathogenicrs74339576GRCh37Chr 11, 17408737: 17408737
26KCNJ11KCNJ11, GLY156ARGundetermined variantPathogenicChr na, -1: -1
27KCNJ11NM_000525.3(KCNJ11): c.844G> A (p.Glu282Lys)SNVPathogenicrs267607196GRCh37Chr 11, 17408795: 17408795
28ABCC8NM_001287174.1(ABCC8): c.4310G> A (p.Arg1437Gln)SNVPathogenicrs387906407GRCh37Chr 11, 17417157: 17417157
29ABCC8NM_001287174.1(ABCC8): c.3992-9G> ASNVPathogenicrs151344623GRCh37Chr 11, 17418602: 17418602
30ABCC8ABCC8, IVS, G-A, -1SNVPathogenicChr na, -1: -1
31ABCC8ABCC8, BRANCH POINT, A-G, -20SNVPathogenicChr na, -1: -1
32ABCC8ABCC8, EX35, G-ASNVPathogenicChr na, -1: -1
33ABCC8NM_001287174.1(ABCC8): c.4058G> C (p.Arg1353Pro)SNVPathogenicrs28936370GRCh37Chr 11, 17418527: 17418527
34ABCC8NM_001287174.1(ABCC8): c.4261C> T (p.Arg1421Cys)SNVPathogenicrs28938469GRCh37Chr 11, 17417206: 17417206
35ABCC8NM_000352.4(ABCC8): c.4477C> T (p.Arg1493Trp)SNVLikely pathogenic, Pathogenicrs28936371GRCh37Chr 11, 17415881: 17415881
36ABCC8NM_001287174.1(ABCC8): c.4519G> A (p.Glu1507Lys)SNVPathogenicrs137852671GRCh37Chr 11, 17415842: 17415842
37ABCC8NM_001287174.1(ABCC8): c.560T> A (p.Val187Asp)SNVPathogenicrs137852672GRCh37Chr 11, 17485004: 17485004
38ABCC8NM_001287174.1(ABCC8): c.4159_4161delTCC (p.Ser1387del)deletionPathogenicrs387906408GRCh37Chr 11, 17417439: 17417441
39ABCC8ABCC8, -64C-GSNVPathogenicChr na, -1: -1

Expression for genes affiliated with Hyperinsulinemic Hypoglycemia, Familial, 2

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Search GEO for disease gene expression data for Hyperinsulinemic Hypoglycemia, Familial, 2.

Pathways for genes affiliated with Hyperinsulinemic Hypoglycemia, Familial, 2

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GO Terms for genes affiliated with Hyperinsulinemic Hypoglycemia, Familial, 2

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Cellular components related to Hyperinsulinemic Hypoglycemia, Familial, 2 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1secretory granule lumenGO:00347749.7GCG, INS
2extracellular spaceGO:00056158.6CHGA, GAST, GCG, IGF2, INS, SCT
3mitochondrionGO:00057397.9ABCC12, GCK, GLUD1, HADH, HADHA, KCNJ11

Biological processes related to Hyperinsulinemic Hypoglycemia, Familial, 2 according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of insulin receptor signaling pathwayGO:004662810.6IGF2, INS
2negative regulation of vasodilationGO:004590810.6CHGA, INS
3negative regulation of gluconeogenesisGO:004572110.6GCK, INS
4positive regulation of glycolytic processGO:004582110.6GCK, INS
5negative regulation of insulin secretionGO:004667610.4ABCC8, HADH, KCNJ11
6cellular response to glucose stimulusGO:007133310.4KCNJ11, MEN1, UCP2
7positive regulation of glycogen biosynthetic processGO:004572510.3GCK, IGF2, INS
8glucose metabolic processGO:000600610.1GCK, IGF2, INS, KCNJ11
9glucose homeostasisGO:00425939.9GCK, HNF4A, INS, SLC16A1
10response to foodGO:00320949.7GAST, SLC16A1
11response to insulinGO:00328689.5ABCC8, HADH, HADHA
12regulation of insulin secretionGO:00507969.2ABCC8, GCG, GCK, HNF4A, KCNJ11, SLC16A1
13response to drugGO:00424939.2ABCC8, HADH, HADHA, HNF4A, IGF2, KCNJ11

Molecular functions related to Hyperinsulinemic Hypoglycemia, Familial, 2 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ATP-activated inward rectifier potassium channel activityGO:001527210.6ABCC8, KCNJ11
23-hydroxyacyl-CoA dehydrogenase activityGO:000385710.3HADH, HADHA
3insulin-like growth factor receptor bindingGO:000515910.3IGF2, INS
4NAD+ bindingGO:00704039.9GLUD1, HADH
5hormone activityGO:00051798.0GAST, GCG, IGF2, INS, SCT, SST

Sources for Hyperinsulinemic Hypoglycemia, Familial, 2

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet