MCID: HYP362
MIFTS: 31

Hyperopia malady

Summaries for Hyperopia

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Hyperopia, commonly known as being farsighted (American English), being longsighted (British English),... more...

MalaCards: Hyperopia is related to astigmatism and amblyopia. An important gene associated with Hyperopia is NYX (nyctalopin). Affiliated tissues include retina, skeletal muscle and endothelial, and related mouse phenotypes are nervous system and vision/eye.

Aliases & Classifications for Hyperopia

Sources:
10DISEASES, 45Novoseek, 61UMLS
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Aliases & Descriptions:

hyperopia 10 45 61


Related Diseases for Hyperopia

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Hyperopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 51)
idRelated DiseaseScoreTop Affiliating Genes
1astigmatism31.1CACNA1F, IFITM2, MATK
2amblyopia30.6ROBO3
3leber congenital amaurosis30.3LRAT, GUCY2D, TULP1
4blindness30.1RS1, GUCY2D
5congenital stationary night blindness30.1NYX, CACNA1F
6irregular astigmatism29.8NYX
7accommodative esotropia10.3
8presbyopia10.3
9ankylosis10.2
10strabismus10.2
11microphthalmia10.1
12sturge-weber syndrome10.1
13weber syndrome10.1
14ocular albinism10.0FRMD7
15cycloplegia10.0IFITM2
16x-linked congenital stationary night blindness10.0CACNA1F, NYX
17oguchi disease 110.0NYX, CACNA1F
18keratoconus10.0KERA, GUCY2D, IFITM2
19cone-rod dystrophy 210.0TULP1, GUCY2D
20night blindness10.0CACNA1F, LRAT, NYX
21hereditary night blindness10.0CACNA1F, NYX
22age related macular degeneration10.0RS1
23aland island eye disease10.0NYX, CACNA1F
24fundus dystrophy10.0LRAT, GUCY2D, TULP1
25retinal disease10.0TULP1, CACNA1F, GUCY2D, NYX, RS1
26rhyns syndrome10.0TULP1, MFRP, GUCY2D, LRAT, RS1
27myopia 610.0CACNA1F, IFITM2, MATK, CFP, NYX
28retinal degeneration10.0TULP1, MFRP, GUCY2D, LRAT, RS1
29congenital nystagmus10.0FRMD7
30anisometropia9.9
31syndactyly9.9
32otosclerosis9.9
33brachydactyly9.9
34ischemic neuropathy9.9
35retinitis pigmentosa9.9
36accommodative spasm9.9
37juvenile glaucoma9.9
38esophageal atresia9.9
39ischemic optic neuropathy9.9
40proximal symphalangism9.9
41short syndrome9.9
42optic neuropathy, anterior ischemic9.9
43central serous chorioretinopathy9.9
44pilodental dysplasia with refractive errors9.9
45isolated microphthalmia9.9
46mental retardation9.9
47microphthalmia, isolated 69.9
48short stature9.9
49nanophthalmos 29.9
50cornea plana congenita, recessive9.9

Graphical network of the top 20 diseases related to Hyperopia:



Diseases related to hyperopia

Clinical Features for Hyperopia

Drugs & Therapeutics for Hyperopia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Hyperopia

Drug clinical trials:

Search ClinicalTrials for Hyperopia

Search NIH Clinical Center for Hyperopia

Search CenterWatch for Hyperopia

Genetic Tests for Hyperopia

Anatomical Context for Hyperopia

Sources:
33MalaCards
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MalaCards organs/tissues related to Hyperopia:

33
Retina, Skeletal muscle, Endothelial

Animal Models for Hyperopia or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Hyperopia:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036319.3CACNA1F, MFRP, GUCY2D, PRSS56, LRAT, ROBO3
2MP:00053918.9RS1, TULP1, CACNA1F, MFRP, GUCY2D, KERA

Publications for Hyperopia

Sources:
51PubMed
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Articles related to Hyperopia:

(show top 50)    (show all 403)
idTitleAuthorsYear
1
Prevalence and 5- to 6-year incidence and progression of myopia and hyperopia in Australian schoolchildren. (23522969)
2013
2
A randomized comparison of pupil-centered versus vertex-centered ablation in LASIK correction of hyperopia. (21726847)
2011
3
Outcomes of wavefront-guided laser in situ keratomileusis for hyperopia. (21511156)
2011
4
The management of childhood esotropia with hyperopia. (21265594)
2011
5
Drug-induced myopia, hyperopia and accommodation disorders. (20738037)
2010
6
Retinoscopy and visual evoked potential based evaluation of the exactness of hyperopia correction in children with developmental difficulties. (21462813)
2010
7
Cycloplegic refractions in children who never wore and who always wore prescribed spectacles for refractive accommodative esotropia: exploring the natural history of this form of strabismus and the effect of treatment on their hyperopia. (19807687)
2009
8
Correction of residual hyperopia after cataract surgery using the light adjustable intraocular lens technology. (19019340)
2009
9
Transient pseudophakic hyperopia after previous radial keratotomy. (19969239)
2009
10
Hyperopia--RLE, pIOL, or LVC? (18242419)
2008
11
Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia. (18334955)
2008
12
Five-year follow-up of 399 phakic Artisan-Verisyse implantation for myopia, hyperopia, and/or astigmatism. (17980432)
2008
13
Survey of german clinical prescribing philosophies for hyperopia. (17299343)
2007
14
Corneal shape and optical performance after one night of corneal refractive therapy for hyperopia. (17435520)
2007
15
Infant and child hyperopia. (17299334)
2007
16
Hyperopia and educational attainment in a primary school cohort. (15665167)
2005
17
Astigmatism in monkeys with experimentally induced myopia or hyperopia. (15829845)
2005
18
Holmium laser thermal keratoplasty for hyperopia in eyes overcorrected with laser in situ keratomileusis for myopia. (15188903)
2004
19
A survey of clinical prescribing philosophies for hyperopia. (15097764)
2004
20
Ablation centration in laser in situ keratomileusis for hyperopia: comparison of VISX S3 ActiveTrak and VISX S2. (14640427)
2003
21
Is skipping child population an indication of unreliability of APEDS data on hyperopia? (12701877)
2003
22
Intraocular pressure after LASIK for hyperopia. (12208713)
2002
23
Results of photorefractive keratectomy for hyperopia using the VISX star excimer laser system. (11828904)
2002
24
Posterior chamber phakic intraocular lens for moderate myopia and hyperopia. (12365662)
2002
25
Laser in situ keratomileusis for correction of hyperopia and hyperopic astigmatism with the Technolas 117C. (12160152)
2002
26
Laser in situ keratomileusis for myopia and hyperopia using the Lasersight 200 laser in 300 consecutive eyes. (11110312)
2000
27
Corneal iron pigmentation after LASIK for hyperopia. (11110320)
2000
28
One-year results of laser vision correction for low to moderate hyperopia. (10647722)
2000
29
Posterior chamber collamer phakic intraocular lens for myopia and hyperopia. (10445712)
1999
30
Laser in situ keratomileusis for hyperopia. (10202723)
1999
31
Centered vs. inferior off-center ablation to correct hyperopia and presbyopia. (9987728)
1999
32
Congenital stapes ankylosis, broad thumbs, and hyperopia: report of a family and refinement of a syndrome. (10069712)
1999
33
Excimer laser assisted in situ keratomileusis for hyperopia. (9951664)
1999
34
Photorefractive keratectomy for hyperopia: six months results in 45 eyes. (9373132)
1997
35
Excimer laser photorefractive keratectomy for hyperopia. (9352478)
1997
36
Extended-wear, soft, contact lenses produce hyperopia in young monkeys. (8887400)
1996
37
Hyperopia correction by noncontact holmium:YAG laser thermal keratoplasty. United States phase IIA clinical study with a 1-year follow-up. (8874423)
1996
38
Implantation of multiple foldable acrylic posterior chamber lenses in the capsular bag for high hyperopia. (9051532)
1996
39
Does experimentally-induced amblyopia cause hyperopia in monkeys? (7610589)
1995
40
Surgical correction of hyperopia: a new experimental approach using X-incision and suture technique in rabbits. (1450123)
1992
41
Correction of hyperopia following radial keratotomy. (2038473)
1991
42
Epikeratophakia for the treatment of hyperopia. (2614710)
1989
43
Leber's congenital amaurosis associated with high hyperopia in four sisters. (2662098)
1989
44
Progressive hyperopia in radial keratotomy. Long-term follow-up of diamond-knife and metal-blade series. (3785887)
1986
45
Hereditary posterior microphthalmos with papillomacular fold and high hyperopia. (6830494)
1983
46
Bilateral microphthalmos without microcornea associated with unusual papillomacular retinal folds and high hyperopia. (1146944)
1975
47
Transient accommodative paralysis and hyperopia in diabetes. (4697220)
1973
48
Letter: Hyperopia in diabetes. (4759441)
1973
49
The accommodation requirement in myopia and hyperopia. Contact lenses versus spectacles. (5155068)
1971
50
Psychological correlates to myopia compared to hyperopia and emmetropia. (6053372)
1967

Genetic Variations for Hyperopia

Expression for genes affiliated with Hyperopia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hyperopia

Search GEO for disease gene expression data for Hyperopia.

Pathways for genes affiliated with Hyperopia

Compounds for genes affiliated with Hyperopia

GO Terms for genes affiliated with Hyperopia

Sources:
16Gene Ontology
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Biological processes related to Hyperopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1visual perceptionGO:0076019.5RS1, NYX, LRAT, KERA, GUCY2D, CACNA1F

Molecular functions related to Hyperopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol-4,5-bisphosphate bindingGO:00554610.2RS1, TULP1

Products for genes affiliated with Hyperopia

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Sources for Hyperopia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet