Aliases & Classifications for Hyperostosis

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Aliases & Descriptions for Hyperostosis:

Name: Hyperostosis 10 47 12 36 65
Hypertrophy of Bone 10
 
Bone Hypertrophy 10

Classifications:



External Ids:

Disease Ontology10 DOID:205
ICD1027 M89.3, M89.30
SNOMED-CT59 13814009, 203514008
MeSH36 D015576
NCIt42 C34712
UMLS65 C0020492

Summaries for Hyperostosis

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Wikipedia:68 Hyperostosis is an excessive growth of bone. It may lead to exostosis. It occurs in many musculoskeletal... more...

MalaCards based summary: Hyperostosis, also known as hypertrophy of bone, is related to tumoral calcinosis, hyperphosphatemic, familial and sost-related sclerosing bone dysplasia. An important gene associated with Hyperostosis is SOST (Sclerostin), and among its related pathways are Negative regulation of TCF-dependent signaling by WNT ligand antagonists and Osteoblast Signaling. Affiliated tissues include bone, bone and breast, and related mouse phenotypes are digestive/alimentary and endocrine/exocrine gland.

Disease Ontology:10 A bone remodeling disease that results in an abnormal growth of located in bone.

Related Diseases for Hyperostosis

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Diseases related to Hyperostosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 525)
idRelated DiseaseScoreTop Affiliating Genes
1tumoral calcinosis, hyperphosphatemic, familial33.1FGF23, GALNT3, KL
2sost-related sclerosing bone dysplasia33.0LRP5, SOST
3worth's syndrome32.8LRP4, LRP5, SOST
4dementia30.1FGF23, TNFRSF11B
5primary hyperparathyroidism30.1ALPL, FGF23
6hypervitaminosis a29.9FGF23, GALNT3, KL
7african tick-bite fever29.4ALPL, FGF23, GALNT3, KL
8diffuse idiopathic skeletal hyperostosis12.6
9hyperostosis, endosteal12.5
10exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis12.5
11hyperostosis cranialis interna12.4
12x-linked calvarial hyperostosis12.3
13calvarial hyperostosis12.3
14dysplastic cortical hyperostosis12.2
15polyosteolysis/hyperostosis syndrome12.2
16short stature cranial hyperostosis hepatomegaly12.2
17short stature, cranial hyperostosis, hepatomegaly and diabetes12.2
18isolated sternocostoclavicular hyperostosis12.2
19pancreatic insufficiency-anemia-hyperostosis syndrome12.2
20familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome12.2
21sapho syndrome12.1
22van buchem disease12.1
23caffey disease12.0
24morgagni-stewart-morel syndrome12.0
25sclerosteosis11.9
26osteopathia striata with cranial sclerosis11.8
27paget disease of bone 5, juvenile-onset11.8
28sclerosteosis 111.7
29camurati-engelmann disease11.5
30weleber hecht bigley syndrome11.3
31beardwell syndrome11.2
32weill-marchesani syndrome 2, dominant10.4LRP5, SOST
33lenz-majewski hyperostotic dwarfism10.4
34peroxisome biogenesis disorder 2a10.4FGF23, GALNT3
35breast cancer10.4
36distal arthrogryposis10.3FGF23, GALNT3
37craniometaphyseal dysplasia10.3
38craniometaphyseal dysplasia, autosomal recessive10.3
39craniodiaphyseal dysplasia, autosomal dominant10.3
40craniodiaphyseal dysplasia10.3
41facial hemiatrophy10.3ANKH, LRP5
42leukemia10.3
43amenorrhea10.3ANKH, LRP5
44axial osteomalacia10.3ALPL, LRP5
45collagenopathy, types ii and xi10.3SOST, TNFRSF11B
46endotheliitis10.3
47lung cancer10.2
48sarcoma10.2
49blood coagulation disease10.2FGF23, TNFRSF11B
50centrotemporal epilepsy10.2COL1A1, LRP5

Graphical network of the top 20 diseases related to Hyperostosis:



Diseases related to hyperostosis

Symptoms for Hyperostosis

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Drugs & Therapeutics for Hyperostosis

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Drugs for Hyperostosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Miconazoleapproved, investigationalPhase 2302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
2
EverolimusapprovedPhase 21797159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
Afinitor Disperz
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
VOTUBIA
Zortress
everolimus
3
Sirolimusapproved, investigationalPhase 2179753123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
4Anti-Bacterial AgentsPhase 29140
5Anti-Infective AgentsPhase 217220
6Antibiotics, AntitubercularPhase 25971
7Immunosuppressive AgentsPhase 210422
8Antifungal AgentsPhase 23015
9Immunologic FactorsPhase 218483
10
PamidronateapprovedPhase 14340391-99-94674
Synonyms:
(3-AMINO-1-HYDROXY-1-PHOSPHONO-PROPYL)PHOSPHONIC ACID
(3-Amino-1-hydroxypropylidene)bisphosphonic acid
(3-Amino-1-hydroxypropylidene)diphosphonic acid
(3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
(3-amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid)
(3-amino-1-hydroxypropylidene)-1,1-biphosphonate
(3-amino-1-hydroxypropylidene)-1,1-bisphosphonate
1-hydroxy-3-aminopropane-1,1-diphosphonic acid
3-Amino-1-hydroxypropylidene-1,1-diphosphonate
40391-99-9
57248-88-1
57248-88-1 (di-hydrochloride salt)
AC1L1IP4
AHPrBP
AKOS003599275
APD
Acide pamidronique
Acide pamidronique [INN-French]
Acido pamidronico
Acido pamidronico [INN-Spanish]
Acidum pamidronicum
Acidum pamidronicum [INN-Latin]
Amidronate
Aminomux
Aredia
BIDD:GT0538
Bisphosphonate 6
C019248
C07395
C3H11NO7P2
 
CHEMBL834
CID4674
ChemDiv1_025240
D07281
DB00282
EINECS 254-905-2
HMS2090C13
HMS658L06
HSCI1_000312
I14-2407
LS-174826
MolPort-002-131-054
NCGC00159433-02
NCGC00159433-03
Novartis brand of pamidronate disodium salt
PAMIDRONATE DISODIUM
PAMIDRONIC ACID
Pamidronate Disodium
Pamidronic acid
Pamidronic acid (INN)
Pamidronic acid [INN:BAN]
Ribodroat
Ribodroat (TN)
STOCK1N-12562
UNII-OYY3447OMC
amino-1-hydroxypropane-1,1-diphosphonate
aminohydroxypropylidene diphosphonate
aminopropanehydroxydiphosphonate
pamidronate
pamidronate calcium
pamidronate monosodium
11Bone Density Conservation AgentsPhase 12600
12DiphosphonatesPhase 1381
13
Sevelamerapproved72152751-57-03085017
Synonyms:
Renagel
Renvela
Sevelamer
Sevelamer Carbonate
 
Sevelamero
Sevelamerum
Sévélamer
sevelamer carbonate
sevelamer hydrochloride
14
Alfacalcidolapproved, nutraceutical4341294-56-85282181
Synonyms:
(5Z,7e)-9,10-Seco-5,7,10(19)-cholestatrien-1alpha,3beta-diol
1-Hydroxycholecalciferol
1-hydroxycholecalciferol
1alpha-Hydroxy-vitamin D3
 
1alpha-hydroxycholecalciferol
1alpha-hydroxyvitamin D3
9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta-diol
Alfacalcidolum
Alsiodol
15Analgesics9358
16Hydroxycholecalciferols92
17Contraceptives, Oral3734

Interventional clinical trials:

(show all 16)
idNameStatusNCT IDPhase
1Chronic Insertional Achilles Tendonitis Treated With or Without Flexor Hallucis Longus Tendon TransferCompletedNCT00950053Phase 4
2Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K ActivationRecruitingNCT02428296Phase 2
3Autologous Stem Cells in Achilles TendinopathyRecruitingNCT02064062Phase 2
4Efficacy of Bisphosphonates in Patients With Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) SyndromeActive, not recruitingNCT02544659Phase 1
5Nottingham Osteoarthritis Biomarker Study 2011CompletedNCT01495455
6Immune Response in the SAPHO SyndromeCompletedNCT01688219
7A Comparison of the Analgesic Efficacies of Ultrasound and Shock Wave Therapy in the Patients With Calcaneal SpurCompletedNCT01510249
8Effectiveness of Manual Therapy Combined With Standard Treatment in the Management of Plantar FasciitisCompletedNCT01439932
9The Health-Related Quality of Life in Patients With Hereditary Multiple ExostosesCompletedNCT00474448
10Genetic and Functional Analysis of Craniometaphyseal Dysplasia (CMD)RecruitingNCT01630460
11Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic DiseaseRecruitingNCT02504879
12Hypophosphatemic Rickets in NorwayActive, not recruitingNCT01057186
13Clinical Observation Study With the SBG StemActive, not recruitingNCT02338661
14Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal SurgeryEnrolling by invitationNCT00984672
15Gene Mutations and Orthopaedic Symptoms Correlation of Multiple Hereditary Exostoses: Multicentre ProjectSuspendedNCT00474331
16Establishing the Genetic Profile of Multiple Hereditary Exostoses (HME) in Families of BCTerminatedNCT00473850

Search NIH Clinical Center for Hyperostosis


Cochrane evidence based reviews: hyperostosis

Genetic Tests for Hyperostosis

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Anatomical Context for Hyperostosis

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MalaCards organs/tissues related to Hyperostosis:

33
Bone, Breast, Endothelial, Lung, Liver, Brain, Thyroid

FMA organs/tissues related to Hyperostosis:

16
Bone

Animal Models for Hyperostosis or affiliated genes

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MGI Mouse Phenotypes related to Hyperostosis:

38 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.7ALPL, COL1A1, FGF23, FLNA, GALNT3, KL
2MP:00053798.1ALPL, COL1A1, FGF23, GALNT3, KL, LRP4
3MP:00053897.4ALPL, ANKH, COL1A1, FGF23, FLNA, GALNT3
4MP:00053887.4ALPL, ANKH, COL1A1, COX4I2, FGF23, FLNA
5MP:00053867.3ALPL, ANKH, COL1A1, COX4I2, FLNA, KL
6MP:00053827.3ALPL, ANKH, COL1A1, FLNA, GALNT3, LRP4
7MP:00053847.2ALPL, ANKH, COL1A1, FLNA, KL, LRP4
8MP:00053857.2ALPL, ANKH, COL1A1, FGF23, FLNA, GALNT3
9MP:00053976.9ALPL, ANKH, COL1A1, FGF23, FLNA, GALNT3
10MP:00053716.9ALPL, ANKH, COL1A1, FGF23, GALNT3, KL
11MP:00053876.8ALPL, ANKH, COL1A1, COX4I2, FGF23, FLNA
12MP:00107686.1ALPL, ANKH, COL1A1, FGF23, FLNA, KL
13MP:00053906.1ALPL, ANKH, COL1A1, FGF23, FLNA, GALNT3
14MP:00053785.9ALPL, ANKH, COL1A1, COX4I2, FGF23, FLNA
15MP:00053765.8ALPL, ANKH, COL1A1, COX4I2, FGF23, FLNA

Publications for Hyperostosis

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Articles related to Hyperostosis:

(show top 50)    (show all 681)
idTitleAuthorsYear
1
Are presynaptic GABA-CI82 receptors involved in anti-nociception? (26327143)
2015
2
JAG1 Mutation Spectrum and Origin in Chinese Children with Clinical Features of Alagille Syndrome. (26076142)
2015
3
Microscopic polyangiitis: Advances in diagnostic and therapeutic approaches. (25992801)
2015
4
Milatuzumab and veltuzumab induce apoptosis through JNK signalling in an NF-I_B dependent human transformed follicular lymphoma cell line. (24386925)
2014
5
Extracellular haemoglobin upregulates and binds to tissue factor on macrophages: implications for coagulation and oxidative stress. (24108579)
2014
6
Projected Cost Comparison of Trabectome, iStent, and Endoscopic Cyclophotocoagulation Versus Glaucoma Medication in the Ontario Health Insurance Plan. (23807348)
2013
7
CRISPLD2 is expressed at low levels during septic shock and is associated with procalcitonin. (23799041)
2013
8
Differential diagnosis of behAset uveitis. (23730816)
2013
9
Contribution of Recurrent Venous Thrombosis and Inherited Thrombophilia to the Pathogenesis of Postthrombotic Syndrome. (23892685)
2013
10
Low recurrence rate and low chronic pain associated with inguinal hernia repair by laparoscopic placement of Parietex ProGripa8c mesh: clinical outcomes of 220 hernias with mean follow-up at 23 months. (23412779)
2013
11
Outcome of gestational diabetes mellitus from a tertiary referral center in South India: a case-control study. (24293841)
2012
12
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15. (23104097)
2012
13
Enoxaparin prevents portal vein thrombosis and liver decompensation in patients with advanced cirrhosis. (22819864)
2012
14
The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement. (22110726)
2011
15
miR-149 promotes epithelial-mesenchymal transition and invasion in nasopharyngeal carcinoma cells. (21873783)
2011
16
Reversal of atrophic body gastritis after H. pylori eradication at long-term follow-up. (21112822)
2011
17
Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components. (20080841)
2010
18
MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia. (20504344)
2010
19
Contribution of SHP-1 protein tyrosine phosphatase to osmotic regulation of the transcription factor TonEBP/OREBP. (20351292)
2010
20
Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas. (19144710)
2009
21
Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice. (19136718)
2009
22
Orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors. (19394219)
2009
23
Inflammatory pseudotumors of the central nervous system. (19656549)
2009
24
Semen evaluation for verification of azoospermia after vasectomy in chimpanzees (Pan troglodytes). (17877328)
2007
25
Structures of wild-type and mutant human spermidine/spermine N1- acetyltransferase, a potential therapeutic drug target. (16455797)
2006
26
Cancer immunotherapy targeting the telomerase reverse transcriptase. (16549043)
2006
27
Identifying protein construct variants with increased crystallization propensity--a case study. (17132859)
2006
28
Involvement of epidermal growth factor receptor signaling pathway in tamoxifen resistance of MCF-7 cells]. (16831274)
2006
29
Alemtuzumab as consolidation after a response to fludarabine is effective in purging residual disease in patients with chronic lymphocytic leukemia. (16618945)
2006
30
Insight on the pathogenesis of diabetic nephropathy from the study of podocyte and mesangial cell biology. (18220580)
2005
31
Regulation of body weight by proopiomelanocortin peptides in humans: lessons from the Nelson syndrome. (16061931)
2005
32
Effects of atrial natriuretic peptide at a low dose on water and electrolyte metabolism during general anesthesia. (15721722)
2005
33
EWSR1 is fused to POU5F1 in a bone tumor with translocation t(6;22)(p21;q12). (15729702)
2005
34
Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients. (15090596)
2004
35
Medical image. Bleeding Meckel's diverticulum diagnosed with enterocolysis and mesenteric angiography. (15505675)
2004
36
Glycine conjugation of para-aminobenzoic acid (PABA): a pilot study of a novel prognostic test in acute liver failure in children. (12499998)
2003
37
An association between chronic infection with Chlamydia pneumoniae and lung cancer. A prospective 2-year study. (11878709)
2001
38
Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing. (10721720)
2000
39
Secondary endocardial fibroelastosis associated with Pompe disease and multicystic dysplastic kidney. (11560361)
2000
40
Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity. (9888831)
1999
41
Aromatase expression and its localization in human breast cancer. (9365204)
1997
42
2',3'-cyclic nucleotide 3'-phosphodiesterase: a novel candidate autoantigen in demyelinating diseases. (9143234)
1997
43
Identification and hypotensive activity of proadrenomedullin N-terminal 20 peptide (PAMP). (8076689)
1994
44
Treatment of genital HPV infection with carbon dioxide laser and systemic interferon alpha-2b. (9071414)
1994
45
The L-arginine-nitric oxide pathway. (7504210)
1993
46
Overview: mechanism of translation initiation in eukaryotes. (2133660)
1990
47
Molecular cloning and nucleotide sequence analysis of mRNA for human kidney ornithine aminotransferase. An examination of ornithine aminotransferase isozymes between liver and kidney. (2507357)
1989
48
Pathology of aspiration pneumonia in mice. (4065213)
1985
49
Pigmented olfactory neuroblastoma: a new example of melanotic neuroepithelial neoplasm. (7074529)
1982
50

Variations for Hyperostosis

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Expression for genes affiliated with Hyperostosis

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Search GEO for disease gene expression data for Hyperostosis.

Pathways for genes affiliated with Hyperostosis

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Pathways related to Hyperostosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
10.0LRP5, SOST
29.5COL1A1, FGF23, TNFRSF11B

GO Terms for genes affiliated with Hyperostosis

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Biological processes related to Hyperostosis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1cellular response to parathyroid hormone stimulusGO:007137410.5FGF23, SOST
2response to magnesium ionGO:00320269.9FGF23, TNFRSF11B
3regulation of canonical Wnt signaling pathwayGO:00608289.7LRP4, LRP5
4endocytosisGO:00068979.6LRP4, LRP5
5receptor clusteringGO:00431139.6FLNA, LRP4
6Wnt signaling pathwayGO:00160559.1LRP4, LRP5, SOST
7extracellular matrix organizationGO:00301988.8COL1A1, LRP4, TNFRSF11B

Sources for Hyperostosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet