Hyperparathyroidism, Neonatal malady

MalaCards: Hyperparathyroidism, Neonatal, also known as hyperparathyroidism, is related to familial isolated hyperparathyroidism and multiple endocrine neoplasia. An important gene associated with Hyperparathyroidism, Neonatal is CASR (calcium-sensing receptor). The drugs calcitriol and dihydrotachysterol have been mentioned in the context of this disorder.

OMIM: 239200

hyperparathyroidism, neonatal 33 hyperparathyroidism 43

Diseases related to hyperparathyroidism, neonatal by text searches and GeneDecks gene sharing:

(show top 50)    (show all 56)

id	Related Disease	Score	Top Affiliating Genes
1	familial isolated hyperparathyroidism	9.6
2	multiple endocrine neoplasia	8.4
3	adenoma	8.1
4	familial hypocalciuric hypercalcemia	8.0
5	hyperparathyroidism, neonatal severe primary	7.9
6	kidney disease	7.3
7	parathyroid adenoma	7.3
8	secondary hyperparathyroidism of renal origin	7.3
9	uremia	7.1
10	parathyroid carcinoma	6.9
11	osteitis fibrosa	6.6
12	pancreatitis	6.6
13	cdc73-related familial isolated hyperparathyroidism	6.2
14	hypocalcemia	6.2
15	hyperparathyroidism 3	6.2
16	hypophosphatemic rickets and hyperparathyroidism	6.2
17	non-renal secondary hyperparathyroidism	6.2
18	nephropathy, deafness, and hyperparathyroidism	6.2
19	pheochromocytoma	6.2
20	peritonitis	6.2
21	rickets	6.2
22	thyroid cancer	6.2
23	fibrous dysplasia	5.7
24	goiter	5.7
25	humoral hypercalcemia of malignancy	5.7
26	hyperthyroidism	5.7
27	insulinoma	5.7
28	multiple endocrine neoplasia type 2a	5.7
29	nephrocalcinosis	5.7
30	renal osteodystrophy	5.7
31	thyroid carcinoma	5.7
32	melanoma	4.8
33	duodenitis	4.8
34	meningioma	4.8
35	neurofibromatosis	4.8
36	follicular adenoma	4.8
37	obesity, association with	4.8
38	ossifying fibroma	4.8
39	hemangioma	4.8
40	papillary carcinoma	4.8
41	papillary thyroid carcinoma	4.8
42	hypoparathyroidism	4.8
43	papilloma	4.8
44	peptic ulcer	4.8
45	aldosteronism	4.8
46	invasive malignant thymoma	4.8
47	kallmann syndrome	4.8
48	parathyroid disorders	4.8
49	long qt syndrome	4.8
50	pituitary adenoma	4.8

Clinical features from OMIM: 239200

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 calcitriol, cod liver oil [va product], dihydrotachysterol, doxercalciferol, paricalcitol

Genes related to hyperparathyroidism, neonatal according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	CASR	calcium-sensing receptor	11.0	Disorders