HTN
MCID: HYP075
MIFTS: 85

Hypertension (HTN) malady

Genetic diseases, Cardiovascular diseases, Blood diseases, Rare diseases categories
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Summaries for Hypertension

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34MedlinePlus, 65Wikipedia, 47OMIM, 33MalaCards
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MedlinePlus:34 Blood pressure is the force of your blood pushing against the walls of your arteries. each time your heart beats, it pumps blood into the arteries. your blood pressure is highest when your heart beats, pumping the blood. this is called systolic pressure. when your heart is at rest, between beats, your blood pressure falls. this is called diastolic pressure. your blood pressure reading uses these two numbers. usually the systolic number comes before or above the diastolic number. a reading of 119/79 or lower is normal blood pressure 140/90 or higher is high blood pressure between 120 and 139 for the top number, or between 80 and 89 for the bottom number is called prehypertension. prehypertension means you may end up with high blood pressure, unless you take steps to prevent it. high blood pressure usually has no symptoms, but it can cause serious problems such as stroke, heart failure, heart attack and kidney failure. you can control high blood pressure through healthy lifestyle habits and taking medicines, if needed. nih: national heart, lung, and blood institute

MalaCards: Hypertension, also known as high blood pressure, is related to essential hypertension and primary pulmonary hypertension. An important gene associated with Hypertension is NOS3 (nitric oxide synthase 3 (endothelial cell)), and among its related pathways are Effects of nitric oxide and Nitric oxide stimulates guanylate cyclase. The drugs diltiazem and felodipine and the compounds nebivolol and metoprolol have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and kidney, and related mouse phenotypes are adipose tissue and muscle.

Wikipedia:65 Hypertension (HTN) or high blood pressure, sometimes called arterial hypertension, is a chronic medical... more...

Description from OMIM:47 145500

Aliases & Classifications for Hypertension

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8Disease Ontology, 47OMIM, 10DISEASES, 34MedlinePlus, 62UMLS, 27ICD9CM, 58SNOMED-CT, 35MeSH, 40NCIt, 25ICD10
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Classifications:



Aliases & Descriptions:

hypertension 8 47 10
high blood pressure 8 34
vascular hypertensive disorder 8
hypertensive disease 62
hyperpiesia 8
htn 8


Related Diseases for Hypertension

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17GeneCards, 18GeneDecks
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Diseases in the Hypertension family:

Benign Essential Hypertension Malignant Essential Hypertension
Essential Hypertension Malignant Hypertension
Familial Hypertension Hypertension, Essential 3
Hypertension, Essential 7 Hypertension, Essential 6
Hypertension, Essential 4 Hypertension, Essential 2
Hypertension, Essential 1 Hypertension, Essential 8
Hypertension, Essential 5

Diseases related to Hypertension via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 1289)
idRelated DiseaseScoreTop Affiliating Genes
1essential hypertension32.2GNB3, AGT
2primary pulmonary hypertension31.7BMPR2, SLC6A4
3portal hypertension31.7BMPR2, NOS3
4hypertensive heart disease31.6NR3C2, ACE
5obesity31.3AGT, NOS3, NPR3, COMT, NR3C2, HSD11B2
6insulin resistance31.3AGT, NOS3, ACE, HSD11B2, SGK1, GNB3
7nephrosclerosis31.3ACE, NR3C2
8diabetes mellitus31.3AGT, NOS3, SGK1, ACE, NR3C2, GNB3
9low renin hypertension31.3HSD11B2
10hyperaldosteronism31.1NR3C2, HSD11B2, ACE
11proteinuria31.0HSD11B2, ACE, NOS3, AGT, ACE2, GNB3
12atherosclerosis30.9AGT, GNB3, NOS3, NOS2, CMA1, NR3C2
13pre-eclampsia30.9SLC6A4, HSD11B2, NR3C2, NOS2, EDN2, AGT
14hypokalemia30.9NR3C2, ACE, HSD11B2
15type 2 diabetes mellitus30.9NOS3, AGT, GNB3, SGK1, ACE
16liver cirrhosis30.8NOS3, HSD11B2, AGT
17myocardial infarction30.8GNB3, AGT, ACE2, COMT, ACE, NOS3
18vascular disease30.8AGT, CMA1, EDN2, SLC6A4, NOS3, NOS2
19coronary artery disease30.8NOS3, AGT, GNB3, ACE
20congenital heart disease30.8SLC6A4, NR3C2, ACE
21congestive heart failure30.8SGK1, NPR3, NR3C2, ACE, AGT
22ischemia30.7SGK1, NOS2, NR3C2, NOS3, AGT
23diabetic nephropathy30.6ACE, NR3C2, AGT, ACE2, SGK1, HSD11B2
24cushing's syndrome30.6NR3C2, HSD11B2
25hypercholesterolemia30.6COMT, AGT, NOS3, GNB3, ACE, NOS2
26acute myocardial infarction30.5AGT, ACE, NR3C2, SLC6A4
27cerebrovascular disease30.4NR3C2, ACE, GNB3, NOS3, ACE2, AGT
28anuria30.3ACE
29glomerulosclerosis30.3ACE, NOS2, AGT
30noonan syndrome30.3ACE2, ACE, AGT
31pseudohypoaldosteronism30.3NR3C2, SGK1
32hyperinsulinism30.2NOS3, AGT, SGK1
33intracranial aneurysm30.2NOS3, ACE2
34hyperglycemia30.2NOS2, NOS3, AGT, HSD11B2, SGK1, ACE
35gitelman syndrome30.1AGT
36breast cancer30.1NR3C2, AGT, COMT, EDN2, HSD11B2, SGK1
37apparent mineralocorticoid excess syndrome30.0NR3C2, HSD11B2
38type 1 diabetes mellitus30.0HSD11B2, ACE, COMT, AGT
39diabetic retinopathy29.9NOS3, ACE, NOS2, AGT
40alzheimer's disease29.9NR3C2, NOS3, SLC6A4, NOS2, COMT
41panic disorder29.9SLC6A4, NPR3, COMT
42focal segmental glomerulosclerosis29.9NOS2, ACE
43chronic kidney failure29.7AGT, NOS3, NR3C2, ACE, SGK1, HSD11B2
44impotence29.7NOS2, NOS3
45renal tubular dysgenesis29.7AGT, ACE
46pure autonomic failure29.7ACE, NEDD4L, GNB3
47anxiety disorder29.7COMT, NR3C2, SLC6A4
48psychotic disorder29.7SLC6A4, GNB3, COMT
49alcohol abuse29.6COMT, SLC6A4
50intracranial hypertension11.1

Graphical network of the top 20 diseases related to Hypertension:



Diseases related to hypertension

Symptoms for Hypertension

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47OMIM
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Clinical features from OMIM:

145500

Drugs & Therapeutics for Hypertension

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Hypertension

Search NIH Clinical Center for Hypertension

Inferred drug relations via UMLS62/NDF-RT41:

Genetic Tests for Hypertension

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Anatomical Context for Hypertension

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33MalaCards
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MalaCards organs/tissues related to Hypertension:

33
Heart, Endothelial, Kidney, Brain, Liver, Lung, Smooth muscle, Testes, Bone, Monocytes, Eye, Placenta, Spleen, Thyroid, Skeletal muscle, Retina, Skin, Prostate, Ovary, Spinal cord, Colon, Pancreas, T cells, Adrenal gland, Breast, Cortex, Medulla oblongata, Pituitary, Hypothalamus, Myeloid, Adrenal cortex, Bone marrow, Lymph node, B cells, Thymus, Small intestine, Pons, Tongue, Cardiac myocytes, Thalamus, Prefrontal cortex, Whole blood, Cerebellum, Adipocyte, Cervix

Animal Models for Hypertension or affiliated genes

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37MGI
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Publications for Hypertension

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52PubMed
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Articles related to Hypertension:

(show top 50)    (show all 15378)
idTitleAuthorsYear
1
Malignant hypertension and interferon-beta: a case report. (24067346)
2013
2
Myocardial performance index and aortic distensibility in patients with different left ventricle geometry in newly diagnosed essential hypertension. (23550550)
2013
3
Hypertension secondary to a periprostatic paraganglioma: case report and review of the literature. (24274233)
2013
4
Hepatic hemodynamics in 24 patients with nodular regenerative hyperplasia and symptomatic portal hypertension. (22554152)
2012
5
Arterial Hypertension, Metabolic Syndrome and Subclinical Cardiovascular Organ Damage in Patients with Asymptomatic Primary Hyperparathyroidism before and after Parathyroidectomy: Preliminary Results. (22719761)
2012
6
Mortality and complications in patients with portal hypertension who underwent transjugular intrahepatic portosystemic shunt (TIPS) - 12 years experience. (22767002)
2012
7
Effects of the Ala379Val polymorphism of lipoprotein-associated phospholipase A2 on thrombosis and inflammation in hypertensive patients. (21880383)
2011
8
Response to intracranial hypertension treatment as a predictor of death in patients with severe traumatic brain injury. (21214327)
2011
9
Mixed treatment comparison of repeated measurements of a continuous endpoint: an example using topical treatments for primary open-angle glaucoma and ocular hypertension. (21728183)
2011
10
Acute pulmonary hypertension in infants and children: cGMP-related drugs. (20216161)
2010
11
Idiopathic intracranial hypertension and facial palsy: case report and review of the literature. (20921567)
2010
12
Successful management of refractory intracranial hypertension from acute hyperammonemic encephalopathy in a woman with ornithine transcarbamylase deficiency. (20422467)
2010
13
The structural and functional consequences of diurnal variations in blood pressure in treated patients with hypertensive cerebrovascular disease. (19337131)
2009
14
Regulation of soluble guanylyl cyclase-alpha1 expression in chronic hypoxia-induced pulmonary hypertension: role of NFATc3 and HuR. (19592461)
2009
15
Genetic variants of beta(1)-adrenoceptor gene polymorphisms (Ser49Gly and Arg389Gly) and essential hypertension in a south Indian Tamil population. (19673943)
2009
16
Pulmonary arterial hypertension: need to treat. (19075794)
2008
17
Physiological significance and therapeutic potential of adrenomedullin in pulmonary hypertension. (16787197)
2006
18
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia. (16606791)
2006
19
Long-term treatment with nifedipine modulates procoagulant marker and C-C chemokine in hypertensive patients with type 2 diabetes mellitus. (15668187)
2005
20
Effects of streptozotocin and dietary fructose on delta-6 desaturation in spontaneously hypertensive rat liver. (15589689)
2004
21
Phosphodiesterase inhibitors in the management of primary pulmonary hypertension. (15133384)
2004
22
What is new in the treatment of pulmonary artery hypertension?]. (12966661)
2003
23
A new mutation, R563Q, of the beta subunit of the epithelial sodium channel associated with low-renin, low-aldosterone hypertension. (12714866)
2003
24
Effect of angiotensin II type 1 receptor antagonist on oxidative stress markers in type 2 diabetic patients with hypertension]. (12877092)
2003
25
Blood pressure increase and incidence of hypertension in relation to inflammation-sensitive plasma proteins. (12482834)
2002
26
Choledocholithiasis in the Setting of Portal Hypertension. (11469971)
2001
27
Outcome of patients with malignant hypertension and end-stage renal failure treated by long-term hemodialysis. (10702650)
1999
28
Doppler sonographic findings for hypertension in pregnancy and HELLP syndrome. (10642960)
1999
29
Adrenomedullin and membrane fluidity of erythrocytes in mild essential hypertension. (10067789)
1999
30
Improvement of insulin resistance in essential hypertension by long-acting Ca antagonist benidipine. (10574416)
1999
31
Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension. (10400907)
1999
32
Primary pulmonary hypertension: pathologist as patient. (9670148)
1998
33
Study on relationship between detection of interleukin-6 and its mRNA and pregnancy induced hypertension]. (10806655)
1998
34
Angiotensin-converting enzyme deletion polymorphism is associated with hypertension in a Sikh population. (9358012)
1997
35
A comparison of outcome criteria in the diagnosis of renovascular hypertension. (8989973)
1996
36
Hypertension and atherosclerosis. (8872835)
1996
37
Urinary excretion rate of endothelin-1 in patients with essential hypertension and salt sensitivity. (8164445)
1994
38
Hyponatremic hypertensive syndrome and massive proteinuria in a patient with renin-producing leiomyosarcoma. (8023829)
1994
39
Mechanisms of renal hypertension and renal contribution to primary hypertension. (8116014)
1993
40
Responsiveness to alpha- and beta-adrenergic receptor agonists. Effects of race in borderline hypertensive compared to normotensive men. (8398005)
1993
41
Renal effects of atrial natriuretic peptide during dopa-decarboxylase inhibition in patients with essential hypertension. (8359177)
1993
42
Percutaneous transluminal renal artery angioplasty (PTRA) in hypertensive encephalopathy. (6223006)
1983
43
Malignant hypertension and cigarette smoking. (427451)
1979
44
A controlled, double-blind study of dl-alpha-tocopheryl nicotinate (Juvela-Nicotinate) for treatment of symptoms in hypertension and cerebral arteriosclerosis. (881743)
1977
45
On the pathogenesis of hypertensive encephalopathy as revealed by cerebral blood flow studies in man. (928747)
1977
46
Reversible renal hypertension secondary to renal arteriovenous fistula and renal cell carcinoma. (833981)
1977
47
Pathogenesis of malignant hypertension: experimental evidence from the renal hypertensive rat. (1192618)
1975
48
Partial splenectomy and pleural splenic transposition, a new approach to congestive hypersplenism of portal hypertension. (5037265)
1972
49
Successful twin pregnancy after treatment of malignant essential hypertension. (13572832)
1958
50
Abdominal epilepsy; diencephalic syndrome, pseudotabes, pupillary anomalies, alterations of reflexes, severe visceral algias, morbid hunger, and juvenile arterial hypertension; observation of a familial picture of five individuals. (13248674)
1954

Variations for Hypertension

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1 National Center for Biotechnology Information (Clinvar)
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Clinvar genetic disease variations for Hypertension:

1
id Gene Name Type Significance SNP ID Assembly Location
1PTGISPTGIS, IVS9, T-C, +2single nucleotide variantPathogenic/card/hypertension

Expression for genes affiliated with Hypertension

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypertension

Search GEO for disease gene expression data for Hypertension.

Pathways for genes affiliated with Hypertension

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50PathCards, 38NCBI BioSystems Database, 55Reactome, 51PharmGKB, 60Thomson Reuters, 54R&D Systems, 30KEGG
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Pathways related to Hypertension according to GeneCards/GeneDecks:

(show all 13)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Quercetin and Nf-kB/ AP-1 induced cell apoptosis38
10.3NOS3, NOS2
2
Show member pathways
10.3NOS3, NOS2
310.3NOS3, NOS2
410.3NOS3, NOS2
510.3ACE, ACE2
6
Show member pathways
10.3NOS3, NOS2, GNB3
7
Show member pathways
citrulline-nitric oxide cycle38
arginine degradation I (arginase pathway)38
proline degradation38
glutamine degradation I38
proline biosynthesis I38
superpathway of citrulline metabolism38
proline biosynthesis II (from arginine)38
citrulline biosynthesis38
arginine degradation VI (arginase 2 pathway)38
Urea cycle and metabolism of amino groups38
asparagine biosynthesis I38
4-hydroxyproline degradation I38
citrulline degradation38
10.2CPS1, NOS2, NOS3
8
Show member pathways
10.1GNB3, COMT, GRK4, SLC6A4
910.1HSD11B2, SGK1, NEDD4L, NR3C2
10
Show member pathways
10.0GNB3, CMA1, ACE2, ACE, AGT
11
Show member pathways
10.0GNB3, CMA1, ACE2, ACE, AGT
12
Show member pathways
10.0AGT, NOS3, NR3C2, ACE, ACE2, CMA1
13
Show member pathways
9.9GNB3, CPS1, ACSM3, COMT, NOS2, NOS3

Compounds for genes affiliated with Hypertension

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45Novoseek, 11DrugBank, 51PharmGKB, 29IUPHAR, 24HMDB, 61Tocris Bioscience
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Compounds related to Hypertension according to GeneCards/GeneDecks:

(show top 50)    (show all 149)
idCompoundScoreTop Affiliating Genes
1nebivolol45 1111.7NOS3, NOS2, ACE
2metoprolol45 51 29 24 1114.6GRK4, NOS3, ACE
3nitroglycerin45 1111.6NOS2, ACE, NOS3, GNB3
4eplerenone45 61 29 1113.6NR3C2, ACE2, ACE
5chymostatin4510.6ACE, AGT, CMA1
6enalaprilat4510.6AGT, ACE, ACE2
7perindopril45 51 1112.6NOS3, AGT, ACE
8lisinopril45 51 24 1113.6ACE2, ACE, AGT
9n(g)-nitro-l-arginine methyl ester4510.6AGT, NOS2, NOS3
10thiazide4510.6GNB3, ACE, NR3C2
11ang ii4510.6NOS3, AGT, NOS2, NR3C2, ACE
12spironolactone45 61 29 51 1114.6ACE, NR3C2, SGK1, HSD11B2
13ng-nitro-l-arginine4510.6AGT, NOS2, NOS3
14magnesium lithospermate b4510.5NOS3, NOS2
15sildenafil29 45 51 24 1114.5NOS2, NOS3, ACE, GNB3, SLC6A4
16atenolol45 51 29 24 1114.5AGT, ACE, GNB3
17benazepril hydrochloride6110.5ACE2, ACE
18prostacyclin4510.5AGT, NOS3, NOS2, ACE, EDN2
1911alpha-hydroxyprogesterone4510.5NR3C2, HSD11B2
20cgmp45 2911.5EDN2, NOS2, NOS3, NPR3, AGT
21captopril45 61 51 29 1114.5AGT, EDN2, ACE2, ACE, NR3C2
22mifepristone45 29 61 1113.5SGK1, NR3C2, NOS3, HSD11B2
23guanylate4510.4NPR3, AGT, NOS2, NOS3
24perindopril erbumine6110.4ACE2, ACE
25hydrochlorothiazide45 29 51 24 1114.4GNB3, HSD11B2, NEDD4L, ACE, NR3C2, AGT
26moexipril hydrochloride6110.4ACE, ACE2
27epinephrine45 24 1112.4EDN2, GNB3, AGT, SLC6A4, COMT
28nadph45 2411.4ACE2, NOS3, AGT, NOS2, NR3C2, HSD11B2
29acetylcholine45 51 29 24 1114.4ACE, EDN2, NOS2, AGT, NOS3
30norepinephrine45 24 1112.3AGT, HSD11B2, SLC6A4, GNB3, ACE, COMT
31actinomycin d4510.3SGK1, HSD11B2, NOS3, AGT, NPR3, NOS2
32candesartan45 51 29 1113.3AGT, NOS3, ACE
33chlorine45 2411.3NPR3, ACE, ACE2, SGK1
34adenylate4510.3HSD11B2, SGK1, NOS2, EDN2, NPR3, AGT
35dopamine45 29 24 1113.3NPR3, GRK4, COMT, SLC6A4, GNB3, AGT
36cholesterol45 29 24 1113.3CMA1, GNB3, HSD11B2, ACE2, NR3C2, AGT
37dexamethasone45 51 29 1113.3NR3C2, SGK1, NOS2, NPR3, AGT, EDN2
38apocynin45 6111.3NOS2, AGT, NOS3
39potassium45 24 1112.3NR3C2, GNB3, AGT, ACE, SGK1, EDN2
40amlodipine45 51 24 1113.3AGT, NOS3, ACE
41oxygen45 2411.3NOS2, AGT, HSD11B2, ACE2, EDN2, BMPR2
42glutamate4510.2NR3C2, SLC6A4, NOS2, GRK4, NOS3, SGK1
43enalapril45 51 1112.2ACE, AGT, NR3C2
44nitric oxide45 24 1112.1NOS2, AGT, NR3C2, NOS3, BMPR2, ACE2
45arginine4510.1NPR3, HSD11B2, SGK1, CPS1, AGT, NOS3
46serine4510.1SLC6A4, BMPR2, CMA1, EDN2, HSD11B2, SGK1
47sodium45 2411.1GRK4, NR3C2, ACE, NEDD4L, SGK1, NPR3
48cysteine4510.1HSD11B2, NEDD4L, NPR3, GRK4, NR3C2, COMT
49calcium45 51 24 1113.0SGK1, HSD11B2, NPR3, NOS3, NOS2, NR3C2
50ketamine45 29 1111.9NOS3, SLC6A4, EDN2

GO Terms for genes affiliated with Hypertension

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16Gene Ontology
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Cellular components related to Hypertension according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:0058869.7SLC6A4, NOS3, COMT, BMPR2, ACE, ACE2

Biological processes related to Hypertension according to GeneCards/GeneDecks:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1regulation of renal output by angiotensinGO:00201910.7AGT, ACE
2nitric oxide mediated signal transductionGO:00726310.6NOS2, NOS3, AGT
3regulation of systemic arterial blood pressure by endothelinGO:00310010.6NOS3, EDN2
4angiotensin-mediated drinking behaviorGO:00305110.6ACE2, AGT
5angiotensin catabolic process in bloodGO:00200510.6ACE2, ACE
6arginine catabolic processGO:00652710.6NOS3, NOS2
7regulation of systemic arterial blood pressure by renin-angiotensinGO:00308110.6ACE, ACE2
8positive regulation of vasodilationGO:04590910.6NOS3, NOS2, CPS1
9cellular sodium ion homeostasisGO:00688310.6AGT, NEDD4L
10negative regulation of systemic arterial blood pressureGO:00308510.6NEDD4L, BMPR2
11positive regulation of guanylate cyclase activityGO:03128410.5NOS3, NOS2
12blood vessel remodelingGO:00197410.5AGT, NOS3, BMPR2, ACE
13artery smooth muscle contractionGO:01482410.5AGT, EDN2
14angiotensin maturationGO:00200310.5CMA1, ACE2, ACE, AGT
15regulation of vasoconstrictionGO:01922910.5AGT, ACE, ACE2, EDN2
16nitric oxide biosynthetic processGO:00680910.5NOS3, NOS2
17regulation of vasodilationGO:04231210.4ACE, ACE2
18regulation of cell proliferationGO:04212710.4SGK1, ACE2, BMPR2, NOS2, AGT
19response to foodGO:03209410.4HSD11B2, CPS1
20regulation of blood pressureGO:00821710.3NPR3, NOS3, ACSM3, ACE, SGK1, GNB3
21response to salt stressGO:00965110.3NEDD4L, AGT
22response to drugGO:04249310.3HSD11B2, CPS1, COMT, SLC6A4
23response to hypoxiaGO:00166610.3SLC6A4, NOS2, HSD11B2
24vasoconstrictionGO:04231010.2SLC6A4, EDN2
25nitric oxide metabolic processGO:04620910.0NOS3, CPS1

Molecular functions related to Hypertension according to GeneCards/GeneDecks:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1nitric-oxide synthase activityGO:00451710.6NOS3, NOS2
2arginine bindingGO:03461810.5NOS2, NOS3
3tetrahydrobiopterin bindingGO:03461710.5NOS2, NOS3
4peptidyl-dipeptidase activityGO:00824110.5ACE, ACE2
5NADPH-hemoprotein reductase activityGO:00395810.5NOS3, NOS2
6endopeptidase activityGO:00417510.4ACE, ACE2, CPS1
7FMN bindingGO:01018110.4NOS2, NOS3
8carboxypeptidase activityGO:00418010.3ACE2, ACE
9peptide hormone bindingGO:01704610.3NPR3, ACE2
10sodium channel regulator activityGO:01708010.2NEDD4L, SGK1
11steroid bindingGO:00549610.0NR3C2, HSD11B2
12protein bindingGO:0055159.7GNB3, CPS1, NEDD4L, ACE, BMPR2, COMMD5

Products for genes affiliated with Hypertension

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  • Antibodies
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  • Antibodies

Sources for Hypertension

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet