MCID: HYP327
MIFTS: 26

Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy malady

Category: Genetic diseases (common)

Aliases & Classifications for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Aliases & Descriptions for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy:

Name: Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy 49 11
Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy 24
Early-Onset Hypertension with Severe Exacerbation in Pregnancy 67
 
Hypertension 36
Eohsep 67

Characteristics:

HPO:

61
hypertension, early-onset, autosomal dominant, with exacerbation in pregnancy:
Inheritance: autosomal dominant inheritance


Classifications:



External Ids:

OMIM49 605115
MedGen34 C1854631
MeSH36 D006973

Summaries for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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UniProtKB/Swiss-Prot:67 Early-onset hypertension with severe exacerbation in pregnancy: Inheritance is autosomal dominant. The disease is characterized by the onset of severe hypertension before the age of 20, and by suppression of aldosterone secretion.

MalaCards based summary: Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy, also known as hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy, is related to pulmonary hypertension and hypertension, essential, and has symptoms including maternal hypertension, decreased circulating renin level and decreased circulating aldosterone level. An important gene associated with Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy is NR3C2 (Nuclear Receptor Subfamily 3 Group C Member 2). Affiliated tissues include breast, heart and brain.

Description from OMIM:49 605115

Related Diseases for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Diseases related to Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 1236)
idRelated DiseaseScoreTop Affiliating Genes
1pulmonary hypertension12.5
2hypertension, essential12.4
3portal hypertension12.3
4renovascular hypertension12.2
5hypertensive heart disease12.2
6hypertensive encephalopathy12.2
7hypertension and brachydactyly syndrome12.1
8ocular hypertension12.1
9heritable pulmonary arterial hypertension12.1
10hypertensive retinopathy12.1
11hypertensive nephropathy12.1
12intracranial hypertension12.1
13malignant hypertension12.0
14renal hypertension12.0
15hyperuricemia, pulmonary hypertension, renal failure, and alkalosis12.0
16pulmonary hypertension, primary, 412.0
17pulmonary hypertension, primary, 312.0
18pulmonary hypertension, primary, 212.0
19hypertension, diastolic12.0
20chronic thromboembolic pulmonary hypertension11.9
21pulmonary hypertension, familial primary, 1, with or without hht11.9
22malignant essential hypertension11.9
23benign essential hypertension11.9
24malignant secondary hypertension11.9
25brachydactyly-arterial hypertension syndrome11.9
26neurogenic hypertension11.9
27pulmonary hypertension, neonatal11.9
28malignant renovascular hypertension11.9
29malignant hypertensive renal disease11.9
30familial hypertension11.9
31renoprival hypertension11.9
32pediatric hypertension11.9
33autosomal dominant progressive nephropathy with hypertension11.8
34idiopathic and/or familial pulmonary arterial hypertension11.8
35pre-eclampsia11.8
36benign hypertensive renal disease11.8
37pseudotumor cerebri11.8
38pulmonary hypertension, chronic thromboembolic, without deep vein thrombosis11.8
39kallikrein hypertension11.8
40diabetes mellitus, noninsulin-dependent, with acanthosis nigricans and hypertension11.8
41pseudohypoaldosteronism, type iie11.8
42hypertension, essential 711.7
43hypertension, essential 811.7
44blind hypertensive eye11.7
45benign secondary hypertension11.7
46benign renovascular hypertension11.7
47familial pulmonary arterial hypertension leucopenia and atrial septal defect11.7
48familial arteriosclerotic leukoencephalopathy, alopecia, lumbago without arterial hypertension11.7
49hypertensive hypokalemia familial11.7
50portal hypertension due to infrahepatic block11.7

Graphical network of the top 20 diseases related to Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy:



Diseases related to hypertension, early-onset, autosomal dominant, with exacerbation in pregnancy

Symptoms for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Clinical features from OMIM:

605115

HPO human phenotypes related to Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy:

id Description Frequency HPO Source Accession
1 maternal hypertension HP:0008071
2 decreased circulating renin level HP:0003351
3 decreased circulating aldosterone level HP:0002924
4 hypertension HP:0000822

Drugs & Therapeutics for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy


Cochrane evidence based reviews: hypertension

Genetic Tests for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Anatomical Context for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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MalaCards organs/tissues related to Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy:

33
Breast, Heart, Brain, T cells, Lung, Kidney, Thyroid

Animal Models for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation... or affiliated genes

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Publications for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Variations for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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UniProtKB/Swiss-Prot genetic disease variations for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy:

67
id Symbol AA change Variation ID SNP ID
1NR3C2p.Ser810LeuVAR_015626rs41511344

Expression for genes affiliated with Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Search GEO for disease gene expression data for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation in Pregnancy.

Pathways for genes affiliated with Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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GO Terms for genes affiliated with Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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Sources for Hypertension, Early-Onset, Autosomal Dominant, with Exacerbation...

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet