MCID: HYP034
MIFTS: 34

Hypertensive Encephalopathy malady

Cardiovascular diseases, Neuronal diseases categories

Summaries for Hypertensive Encephalopathy

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66Wikipedia, 34MalaCards
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Wikipedia:66 Hypertensive encephalopathy is a neurological dysfunction induced by malignant hypertension. The term... more...

MalaCards: Hypertensive Encephalopathy is related to hypertension and cerebritis. An important gene associated with Hypertensive Encephalopathy is EPO (erythropoietin), and among its related pathways are TGF-Beta Pathway and Development Angiotensin activation of ERK. The compounds aminoguanidine and enalapril have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and spinal cord.

Aliases & Classifications for Hypertensive Encephalopathy

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9Disease Ontology, 46Novoseek, 63UMLS, 59SNOMED-CT, 41NCIt, 28ICD9CM, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases, Neuronal diseases


Aliases & Descriptions:

hypertensive encephalopathy 9 46 63


External Ids:

Disease Ontology9 DOID:9427
NCIt41 C3503
ICD9CM28 437.2
MeSH36 D020343
ICD1026 I67.4

Related Diseases for Hypertensive Encephalopathy

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Hypertensive Encephalopathy:



Diseases related to hypertensive encephalopathy

Symptoms for Hypertensive Encephalopathy

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Drugs & Therapeutics for Hypertensive Encephalopathy

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Hypertensive Encephalopathy

Drug clinical trials:

Search ClinicalTrials for Hypertensive Encephalopathy

Search NIH Clinical Center for Hypertensive Encephalopathy

Search CenterWatch for Hypertensive Encephalopathy

Genetic Tests for Hypertensive Encephalopathy

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Anatomical Context for Hypertensive Encephalopathy

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34MalaCards
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MalaCards organs/tissues related to Hypertensive Encephalopathy:

34
Brain, Kidney, Spinal cord, Cerebellum, Pons

Animal Models for Hypertensive Encephalopathy or affiliated genes

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Publications for Hypertensive Encephalopathy

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53PubMed
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Articles related to Hypertensive Encephalopathy:

(show top 50)    (show all 228)
idTitleAuthorsYear
1
Hypertensive encephalopathy with reversible brainstem edema. (24175031)
2013
2
Concealed primary aortic sarcoma induced hypertensive encephalopathy resulting from a thoracic aortic occlusion: a case report. (23597173)
2013
3
Hypertensive encephalopathy: a rare presentation of Williams-Beuren Syndrome. (21798143)
2011
4
Isolated brainstem involvement in a patient with hypertensive encephalopathy. (20714952)
2010
5
Torsade de pointes: an unknown complication of hypertensive encephalopathy. (18251010)
2008
6
Hypertensive encephalopathy presenting with isolated brain stem and cerebellar edema. (18321248)
2008
7
Zonisamide eradicated paroxysmal headache with EEG abnormalities triggered by hypertensive encephalopathy due to purpura nephritic syndrome. (16806778)
2006
8
Chronic hypertensive encephalopathy showing only headache: report of a case with long-standing brain MR abnormalities suggesting extensive vasogenic edema. (16015008)
2005
9
An unusual case of hypertensive encephalopathy. (15851096)
2005
10
Hypertensive encephalopathy in cats with reduced renal function. (16145210)
2005
11
Hypertensive encephalopathy with predominant brain stem involvement: MRI findings. (14730329)
2004
12
Brainstem involvement in hypertensive encephalopathy: clinical and radiological findings. (15534284)
2004
13
CT and MRI findings of cyclosporine-related encephalopathy and hypertensive encephalopathy. (11956721)
2002
14
Acute and chronic hypertensive headache and hypertensive encephalopathy. (12100095)
2002
15
Hypertensive encephalopathy: persistent MR-abnormalities in a patient with good clinical recovery. (12220388)
2002
16
Reversible posterior leukoencephalopathy syndrome in a patient with hypertensive encephalopathy--case report. (11488003)
2001
17
Preeclampsia-eclampsia: clinical and neuroradiographic correlates and insights into the pathogenesis of hypertensive encephalopathy. (11058630)
2000
18
Assessment of cerebral microcirculation in a patient with hypertensive encephalopathy using MR perfusion imaging. (10584788)
1999
19
Hypertensive encephalopathy, reversible occipitoparietal encephalopathy, or reversible posterior leukoencephalopathy: three names for an old syndrome. (10342593)
1999
20
Venous hypertensive encephalopathy. (9726466)
1998
21
Dementia resulting from dural arteriovenous fistulas: the pathologic findings of venous hypertensive encephalopathy. (9726465)
1998
22
Hypertensive encephalopathy. (9272329)
1997
23
A case of Guillain-BarrAc syndrome accompanied by sympathetic overactivity and hypertensive encephalopathy. (8863889)
1996
24
Transient cortical blindness due to hypertensive encephalopathy. Magnetic resonance imaging correlation. (8501259)
1993
25
Cocaine induced hypertensive encephalopathy. (1927636)
1991
26
Factors influencing the development of hypertensive encephalopathy in acute glomerulonephritis. (3252963)
1988-1989
27
Hypertensive encephalopathy. Magnetic resonance imaging demonstration of reversible cortical and white matter lesions. (3178528)
1988
28
Hypertensive encephalopathy: report of a case. (3771307)
1986
29
Percutaneous transluminal renal artery angioplasty (PTRA) in hypertensive encephalopathy. (6223006)
1983
30
Treatment of hypertensive encephalopathy. (6681555)
1983
31
Hypertensive encephalopathy as a complication of femoral lengthening. (6109565)
1981
32
Intracranial pressure monitoring in severe hypertensive encephalopathy. (6790226)
1981
33
Hypertensive encephalopathy and the neurological manifestations of malignant hypertension. (553413)
1979
34
Hypertensive encephalopathy: recognition and management. (718353)
1978
35
On the pathogenesis of hypertensive encephalopathy as revealed by cerebral blood flow studies in man. (928747)
1977
36
Correspondence: Diazoxide in treatment of severe pre-eclampsia and hypertensive encephalopathy. (961775)
1976
37
Medical Grand Rounds--From the Medical College of Virginia. Hypertensive encephalopathy. Recent developments in pathogenesis as related to treatment. (4853149)
1974
38
Pathogenesis of hypertensive encephalopathy. (4120370)
1973
39
Hypertensive encephalopathy. (5063657)
1972
40
An electron microscope study of hypertensive encephalopathy in the rat with renal hypertension. (5104780)
1971
41
Treatment of "accelerated" or malignant hypertension. I. Hypertensive encephalopathy. (5946464)
1966
42
The significance of hypertensive encephalopathy. (13689595)
1958-1959
43
Hypertensive encephalopathy in a child. (13463367)
1957
44
Intractable, severe hypertensive disease; observations on resistance to treatment with current drugs, denervation of the carotid sinuses, hypertensive encephalopathy, and other complications. (13361573)
1956
45
Malignant hypertension and hypertensive encephalopathy. (13016599)
1953
46
Hypertensive encephalopathy. (14779020)
1950
47
Hypertensive encephalopathy after administration of benzodioxan. (15402383)
1950
48
Hypertensive encephalopathy and cerebral arteriosclerosis. (18151408)
1949
49
Hypertensive encephalopathy. (18875749)
1948
50
The use of aminophylline in neuropsychiatric disorders associated with cerebral arteriosclerosis and hypertensive encephalopathy. (20243407)
1947

Variations for Hypertensive Encephalopathy

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Expression for genes affiliated with Hypertensive Encephalopathy

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypertensive Encephalopathy

Search GEO for disease gene expression data for Hypertensive Encephalopathy.

Pathways for genes affiliated with Hypertensive Encephalopathy

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51PathCards, 54QIAGEN, 61Thomson Reuters
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Pathways related to Hypertensive Encephalopathy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1AGTR1, EPO
2
Show member pathways
Development EDNRB signaling61
Development ACM2 and ACM4 activation of ERK61
Cell adhesion Integrin inside out signaling61
Development G Proteins mediated regulation MARK ERK signaling61
Signal transduction IP3 signaling61
Development Angiotensin signaling via PYK261
Development EPO induced MAPK pathway61
9.1AGTR1, EPO

Compounds for genes affiliated with Hypertensive Encephalopathy

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Sources:
46Novoseek, 30IUPHAR, 12DrugBank, 52PharmGKB, 3BitterDB, 62Tocris Bioscience, 25HMDB
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Compounds related to Hypertensive Encephalopathy according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1aminoguanidine46 30 1211.4AGTR1, EPO
2enalapril46 52 1211.4AGTR1, EPO
3azathioprine46 3 52 1212.3EPO, AGTR1
4vitamin d469.3AGTR1, EPO
5cyclosporin a46 30 6211.3AGTR1, EPO
6cisplatin46 52 62 1212.2EPO, AGTR1
7creatinine469.2AGTR1, EPO
8vegf469.1AGTR1, EPO
9tyrosine469.1AGTR1, EPO
10phosphatidylinositol469.0EPO, AGTR1
11oxygen46 259.8AGTR1, EPO

GO Terms for genes affiliated with Hypertensive Encephalopathy

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Products for genes affiliated with Hypertensive Encephalopathy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hypertensive Encephalopathy

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet