Aliases & Classifications for Hypertensive Retinopathy

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Aliases & Descriptions for Hypertensive Retinopathy:

Name: Hypertensive Retinopathy 8 10 61


External Ids:

Disease Ontology8 DOID:11561
NCIt39 C3514
ICD9CM27 362.11
MeSH33 D058437

Summaries for Hypertensive Retinopathy

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Wikipedia:64 Hypertensive retinopathy is damage to the retina and retinal circulation due to high blood pressure... more...

MalaCards based summary: Hypertensive Retinopathy is related to vascular disease and atherosclerosis. An important gene associated with Hypertensive Retinopathy is FTH1 (ferritin, heavy polypeptide 1), and among its related pathways are Glucose / Energy Metabolism and Binding and Uptake of Ligands by Scavenger Receptors. The compounds olmesartan and metoprolol have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and heart, and related mouse phenotypes are tumorigenesis and renal/urinary system.

Related Diseases for Hypertensive Retinopathy

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Diseases related to Hypertensive Retinopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idRelated DiseaseScoreTop Affiliating Genes
1vascular disease29.8ACE, ADIPOQ
2atherosclerosis29.7ADIPOQ, ACE, ALB
3coronary artery disease29.6ACE, ADIPOQ
4malignant hypertension10.5
5pheochromocytoma10.4
6retinitis10.4
7hepatorenal syndrome10.4ALB
8anuria10.3ACE
9renovascular hypertension10.3
10liver disease10.2ALB, FTH1
11neuroretinitis10.2
12eclampsia10.2
13galactosemia10.1ADIPOQ, ALB
14uremia10.1ALB, ADIPOQ
15nutritional deficiency disease10.1ALB, ADIPOQ
16hypertensive nephropathy10.1ALB, ACE
17renal artery disease10.1ALB, ACE
18peripheral vascular disease10.1ACE, ALB
19focal segmental glomerulosclerosis10.0ALB, ACE
20cork-handlers' disease10.0ALB, ACE
21hepatitis c10.0ALB, FTH1
22glomerulosclerosis10.0ALB, ACE
23microvascular complications of diabetes 510.0ACE, ALB
24systemic lupus erythematosus10.0
25apparent mineralocorticoid excess10.0
26aortic atherosclerosis10.0
27macular holes10.0
28choroiditis10.0
29sensorineural hearing loss10.0
30brachydactyly10.0
31artery disease10.0
32lupus erythematosus10.0
33neuropathy10.0
34pre-eclampsia10.0
35retinal detachment10.0
36retinal vascular disease10.0
37scleroderma10.0
38pheochromocytoma-islet cell tumor syndrome10.0
39endotheliitis10.0
40iga glomerulonephritis10.0ALB, ACE
41stroke, ischemic10.0ALB, ACE
42nephritis10.0ACE, ALB
43idiopathic edema10.0ACE, ADIPOQ
44nephrotic syndrome10.0ALB, ACE
45lipid metabolism disorder10.0ACE, ADIPOQ
46diabetes mellitus, insulin-dependent10.0ALB, ACE
47liver cirrhosis10.0ADIPOQ, ALB
48familial hyperlipidemia10.0ADIPOQ, ACE
49hypercholesterolemia, familial9.9ACE, ADIPOQ
50primary hyperoxaluria9.9ACE, ALB

Graphical network of the top 20 diseases related to Hypertensive Retinopathy:



Diseases related to hypertensive retinopathy

Symptoms for Hypertensive Retinopathy

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Drugs & Therapeutics for Hypertensive Retinopathy

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Drug clinical trials:

Search ClinicalTrials for Hypertensive Retinopathy

Search NIH Clinical Center for Hypertensive Retinopathy

Genetic Tests for Hypertensive Retinopathy

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Anatomical Context for Hypertensive Retinopathy

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MalaCards organs/tissues related to Hypertensive Retinopathy:

31
Retina, Eye, Heart, Breast, Endothelial

Animal Models for Hypertensive Retinopathy or affiliated genes

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MGI Mouse Phenotypes related to Hypertensive Retinopathy:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.5ALB, ACE, ADIPOQ
2MP:00053678.2ALB, ACE, ADIPOQ
3MP:00053708.1ALB, ACE, FTH1, ADIPOQ
4MP:00053768.1ALB, ACE, FTH1, ADIPOQ
5MP:00053848.0ADIPOQ, FTH1, ACE, ALB

Publications for Hypertensive Retinopathy

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Articles related to Hypertensive Retinopathy:

(show top 50)    (show all 132)
idTitleAuthorsYear
1
Bilateral hypertensive retinopathy diagnostic of pheochromocytoma. (25443213)
2015
2
Hypertensive retinopathy and its association with cardiovascular, renal and cerebrovascular morbidity in Congolese patients. (25629539)
2014
3
Bilateral Hypertensive Retinopathy Complicated with Retinal Neovascularization: Panretinal Photocoagulation or Intravitreal Anti-VEGF Treatment? (25232335)
2014
4
The association between endothelial dysfunction and hypertensive retinopathy in essential hypertension. (24441931)
2014
5
Hypertensive retinopathy and risk of stroke. (23940194)
2013
6
Systemic hypertension and hypertensive retinopathy following PPA overdose in a dog. (23148140)
2013
7
Hypertensive retinopathy: incidence, risk factors, and comorbidities. (22468968)
2012
8
Hypertensive retinopathy in a child caused by pheochromocytoma: identification after a failed school vision screening. (22245022)
2012
9
Microalbuminuria and hypertensive retinopathy among newly diagnosed nondiabetic hypertensive adult Nigerians. (22248945)
2011
10
Support system for the preventive diagnosis of hypertensive retinopathy. (21097309)
2010
11
Serum ferritin levels correlate with hypertensive retinopathy. (20110920)
2010
12
Relationship between left ventricular hypertrophy, hypertensive retinopathy, microalbuminuria and echocardiographic modalities in newly diagnosed hypertensive patients. (20111906)
2010
13
Prevalence and severity of hypertensive retinopathy in children. (19571332)
2009
14
Hypertensive retinopathy and sensorineural hearing loss. (23120650)
2009
15
Severe bilateral hypertensive retinopathy and optic neuropathy in a patient with pheochromocytoma. (18454411)
2008
16
Hypertensive retinopathy: a window to vascular remodeling in arterial hypertension. (17998472)
2008
17
The relationship between the breast arterial calcification detected by mammography and the hypertensive retinopathy in hypertensive women. (18682669)
2008
18
Pathological changes in human retinal ganglion cells associated with diabetic and hypertensive retinopathy. (17186260)
2007
19
Relationship of early hypertensive retinopathy to inflammation markers and microalbuminuria in hypertensive patients with regulated blood pressure. (17334487)
2007
20
Bilateral foveal neurosensory detachment in hypertensive retinopathy demonstrated by optical coherence tomography. (16575418)
2006
21
Fred Hollows lecture: hypertensive retinopathy - a journey from fundoscopy to digital imaging. (16872333)
2006
22
Hypertensive retinopathy revisited: some answers, more questions. (16299149)
2005
23
Hypertensive retinopathy. (15564546)
2004
24
Serum level of low-density lipoprotein cholesterol in hypertensive retinopathy. (12971535)
2003
25
Bilateral renal artery stenosis presenting as hypertensive retinopathy and choroidopathy. (12355701)
2002
26
Is leptin associated with hypertensive retinopathy? (10690876)
2000
27
Reversible hypertensive retinopathy in a child with bilateral pheochromocytoma after tumor resection. (11155750)
2000
28
Dramatic regression of hypertensive retinopathy following renal transplantation: a case report. (9595099)
1998
29
Hypertensive retinopathy mimicking neuroretinitis in a twelve-year-old girl. (9220570)
1997
30
Hypertensive retinopathy: a review of existing classification systems and a suggestion for a simplified grading system. (8867562)
1996
31
Hypertensive retinopathy: a cause of decreased visual acuity in children. (1432515)
1992
32
Hypertensive retinopathy caused by a rare ovarian tumor: case report and photo essay. (1814990)
1991
33
Cicletanine and hypertensive retinopathy. (2090985)
1990
34
Hypertensive retinopathy. (6544301)
1983
35
Hypertensive retinopathy and generalized scleroderma. (7325205)
1981
36
Hypertensive retinopathy in renovascular hypertension. (7360168)
1980
37
Pathogenesis of hypertensive retinopathy: a review. (399635)
1979
38
The regression of hypertensive retinopathy. (649917)
1978
39
Reversible hypertensive retinopathy. (301240)
1977
40
Pathogenesis of hypertensive retinopathy. An experimental study in the monkey. (804913)
1975
41
Editorial: Hypertensive retinopathy. (807893)
1975
42
Role of local factors in hypertensive retinopathy. (4461687)
1974
43
Experimental hypertensive retinopathy: ultrastructure. (4998607)
1971
44
The rarity of hypertensive retinopathy in the African. (5672739)
1968
45
CHOKED DISC OR HYPERTENSIVE RETINOPATHY IV? (14213922)
1964
46
THE PATHOLOGY OF COTTON WOOL SPOTS AND CYTOID BODIES IN HYPERTENSIVE RETINOPATHY AND OTHER DISEASES. (14123190)
1963
47
The treatment of hypertensive retinopathy. (13339163)
1956
48
Hypertensive retinopathy and its medical treatment. (13215778)
1954
49
Diabetic and hypertensive retinopathy. (14888036)
1951
50
Hypertensive retinopathy in a girl aged 10 years 11 months. (21001842)
1946

Variations for Hypertensive Retinopathy

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Expression for genes affiliated with Hypertensive Retinopathy

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Search GEO for disease gene expression data for Hypertensive Retinopathy.

Pathways for genes affiliated with Hypertensive Retinopathy

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Pathways related to Hypertensive Retinopathy according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5FTH1, ADIPOQ
2
Show member pathways
9.2ALB, FTH1

Compounds for genes affiliated with Hypertensive Retinopathy

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Compounds related to Hypertensive Retinopathy according to GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idCompoundScoreTop Affiliating Genes
1olmesartan44 28 1111.8ACE, ADIPOQ
2metoprolol44 50 28 24 1113.8ADIPOQ, ACE
3metformin44 50 1111.7ACE, ADIPOQ
4pravastatin44 50 28 24 1113.6ACE, ADIPOQ
5atorvastatin44 50 28 24 1113.6ACE, ADIPOQ
6aopp449.6ADIPOQ, ALB
7halothane44 50 28 1112.6FTH1, ALB
8gliclazide44 50 1111.5ADIPOQ, ALB
9nifedipine44 28 50 1112.5ADIPOQ, ACE
10saquinavir44 1110.5ADIPOQ, ALB
11rosuvastatin44 50 28 1112.5ADIPOQ, ALB
1225-hydroxyvitamin d449.5ADIPOQ, ALB
13olanzapine44 50 28 24 1113.5ALB, ADIPOQ
14indapamide44 1110.5ALB, ACE
15fosinopril44 1110.5ALB, ACE
16uric acid44 2410.5ADIPOQ, ALB
17mannitol44 1110.5ALB, FTH1
18lisinopril44 50 24 1112.5ALB, ACE
19zidovudine44 50 1111.4ALB, ADIPOQ
20perindopril44 50 1111.4ACE, ALB
21hydrochlorothiazide44 28 50 24 1113.4ACE, ALB
22spironolactone44 60 28 50 1113.4ACE, ALB
23estrone44 28 24 1112.4ADIPOQ, ALB
24palmitate449.4ADIPOQ, ALB
25furosemide44 60 28 50 24 1114.4ALB, ACE
26homocysteine44 2410.4ADIPOQ, ALB
27captopril44 60 50 28 1113.4ALB, ACE
28warfarin44 50 24 1112.4ALB, ACE
29kininogen449.4ACE, ALB
30rosiglitazone28 44 50 24 1113.4ADIPOQ, ALB
31prostacyclin449.3ACE, ADIPOQ
32aspirin44 50 28 2412.3ACE, ADIPOQ
33citrate449.3ADIPOQ, ALB
34thyroxine44 2410.2ALB, ADIPOQ
35folate449.2ALB, ADIPOQ
36ascorbic acid44 2410.1ADIPOQ, FTH1, ALB
37tacrolimus44 50 1111.0ALB, ADIPOQ
38ramipril44 1110.0ALB, ADIPOQ, ACE
39valsartan44 60 28 1112.0ACE, ADIPOQ, ALB
40telmisartan44 28 1111.0ACE, ADIPOQ, ALB
41irbesartan44 28 50 1112.0ADIPOQ, ACE, ALB
42candesartan44 50 28 1112.0ADIPOQ, ACE, ALB
43enalapril44 50 1111.0ALB, ACE, ADIPOQ
44amlodipine44 50 24 1111.9ALB, ACE, ADIPOQ
45losartan44 50 28 1111.9ALB, ACE, ADIPOQ
46creatinine448.9ACE, ADIPOQ, ALB
47cholesterol44 28 24 1111.8ALB, ACE, ADIPOQ
48vitamin a44 24 1110.8ALB, ADIPOQ
49glucose448.7ADIPOQ, ACE, ALB
50lipid448.5ALB, ACE, FTH1, ADIPOQ

GO Terms for genes affiliated with Hypertensive Retinopathy

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Cellular components related to Hypertensive Retinopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.5ALB, ACE, ADIPOQ

Biological processes related to Hypertensive Retinopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to nutrientGO:00075849.1ALB, ADIPOQ

Molecular functions related to Hypertensive Retinopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1drug bindingGO:00081448.7ALB, ACE
2protein bindingGO:00055157.5ALB, ACE, FTH1, PSMD9, ADIPOQ

Sources for Hypertensive Retinopathy

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet