MCID: HYP008
MIFTS: 43

Hypertensive Retinopathy malady

Eye diseases category
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Summaries for Hypertensive Retinopathy

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Wikipedia:65 Hypertensive retinopathy is damage to the retina and retinal circulation due to high blood pressure... more...

MalaCards based summary: Hypertensive Retinopathy is related to hypertension and essential hypertension. An important gene associated with Hypertensive Retinopathy is FTH1 (ferritin, heavy polypeptide 1), and among its related pathways are Glucose / Energy Metabolism and Binding and Uptake of Ligands by Scavenger Receptors. The compounds olmesartan and metoprolol have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and heart, and related mouse phenotypes are tumorigenesis and renal/urinary system.

Aliases & Classifications for Hypertensive Retinopathy

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Hypertensive Retinopathy, Aliases & Descriptions:

Name: Hypertensive Retinopathy 8 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


External Ids:

Disease Ontology8 DOID:11561
ICD9CM27 362.11
NCIt39 C3514
MeSH34 D058437

Related Diseases for Hypertensive Retinopathy

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Diseases related to Hypertensive Retinopathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1hypertension31.5ALB, ACE
2essential hypertension30.0ALB, ACE, ADIPOQ
3vascular disease29.8ACE, ADIPOQ
4atherosclerosis29.7ADIPOQ, ACE, ALB
5malignant hypertension10.4
6retinitis10.4
7hepatorenal syndrome10.4ALB
8pheochromocytoma10.3
9anuria10.3ACE
10renovascular hypertension10.3
11eclampsia10.2
12neuroretinitis10.2
13galactosemia10.1ADIPOQ, ALB
14uremia10.1ALB, ADIPOQ
15hypertensive nephropathy10.1ALB, ACE
16renal artery disease10.1ALB, ACE
17peripheral vascular disease10.1ACE, ALB
18focal segmental glomerulosclerosis10.0ALB, ACE
19hepatitis c10.0ALB, FTH1
20cork-handlers' disease10.0ALB, ACE
21glomerulosclerosis10.0ALB, ACE
22diabetic retinopathy10.0ACE, ALB
23aortic atherosclerosis10.0
24systemic lupus erythematosus10.0
25macular holes10.0
26sensorineural hearing loss10.0
27brachydactyly10.0
28choroiditis10.0
29artery disease10.0
30lupus erythematosus10.0
31neuropathy10.0
32pre-eclampsia10.0
33retinal detachment10.0
34retinal vascular disease10.0
35scleroderma10.0
36endotheliitis10.0
37berger disease10.0ALB, ACE
38stroke, ischemic10.0ALB, ACE
39nephritis10.0ACE, ALB
40idiopathic edema10.0ACE, ADIPOQ
41nephrotic syndrome10.0ALB, ACE
42liver cirrhosis10.0ADIPOQ, ALB
43type 1 diabetes mellitus10.0ALB, ACE
44familial hyperlipidemia10.0ADIPOQ, ACE
45hypercholesterolemia10.0ACE, ADIPOQ
46primary hyperoxaluria9.9ACE, ALB
47congenital heart disease9.9ACE, ADIPOQ
48arthritis9.9ALB, FTH1, ADIPOQ
49hepatitis b9.9ALB, ADIPOQ
50deficiency anemia9.9ALB, ACE, FTH1

Graphical network of the top 20 diseases related to Hypertensive Retinopathy:



Diseases related to hypertensive retinopathy

Symptoms for Hypertensive Retinopathy

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Drugs & Therapeutics for Hypertensive Retinopathy

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Drug clinical trials:

Search ClinicalTrials for Hypertensive Retinopathy

Search NIH Clinical Center for Hypertensive Retinopathy

Genetic Tests for Hypertensive Retinopathy

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Anatomical Context for Hypertensive Retinopathy

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MalaCards organs/tissues related to Hypertensive Retinopathy:

32
Retina, Eye, Heart, Breast, Endothelial

Animal Models for Hypertensive Retinopathy or affiliated genes

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MGI Mouse Phenotypes related to Hypertensive Retinopathy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.5ALB, ACE, ADIPOQ
2MP:00053678.2ALB, ACE, ADIPOQ
3MP:00053708.1ALB, ACE, FTH1, ADIPOQ
4MP:00053768.1ALB, ACE, FTH1, ADIPOQ
5MP:00053848.0ADIPOQ, FTH1, ACE, ALB

Publications for Hypertensive Retinopathy

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Articles related to Hypertensive Retinopathy:

(show top 50)    (show all 127)
idTitleAuthorsYear
1
Bilateral Hypertensive Retinopathy Complicated with Retinal Neovascularization: Panretinal Photocoagulation or Intravitreal Anti-VEGF Treatment? (25232335)
2014
2
The association between endothelial dysfunction and hypertensive retinopathy in essential hypertension. (24441931)
2014
3
Hypertensive retinopathy and risk of stroke. (23940194)
2013
4
Hypertensive retinopathy: incidence, risk factors, and comorbidities. (22468968)
2012
5
Hypertensive retinopathy in a child caused by pheochromocytoma: identification after a failed school vision screening. (22245022)
2012
6
Microalbuminuria and hypertensive retinopathy among newly diagnosed nondiabetic hypertensive adult Nigerians. (22248945)
2011
7
Support system for the preventive diagnosis of hypertensive retinopathy. (21097309)
2010
8
Serum ferritin levels correlate with hypertensive retinopathy. (20110920)
2010
9
Relationship between left ventricular hypertrophy, hypertensive retinopathy, microalbuminuria and echocardiographic modalities in newly diagnosed hypertensive patients. (20111906)
2010
10
Prevalence and severity of hypertensive retinopathy in children. (19571332)
2009
11
Hypertensive retinopathy and sensorineural hearing loss. (23120650)
2009
12
Severe bilateral hypertensive retinopathy and optic neuropathy in a patient with pheochromocytoma. (18454411)
2008
13
Hypertensive retinopathy: a window to vascular remodeling in arterial hypertension. (17998472)
2008
14
The relationship between the breast arterial calcification detected by mammography and the hypertensive retinopathy in hypertensive women. (18682669)
2008
15
Pathological changes in human retinal ganglion cells associated with diabetic and hypertensive retinopathy. (17186260)
2007
16
Relationship of early hypertensive retinopathy to inflammation markers and microalbuminuria in hypertensive patients with regulated blood pressure. (17334487)
2007
17
Bilateral foveal neurosensory detachment in hypertensive retinopathy demonstrated by optical coherence tomography. (16575418)
2006
18
Fred Hollows lecture: hypertensive retinopathy - a journey from fundoscopy to digital imaging. (16872333)
2006
19
Hypertensive retinopathy revisited: some answers, more questions. (16299149)
2005
20
Hypertensive retinopathy. (15564546)
2004
21
Serum level of low-density lipoprotein cholesterol in hypertensive retinopathy. (12971535)
2003
22
Racial differences in the prevalence of hypertensive retinopathy. (12654714)
2003
23
Malignant hypertensive retinopathy-clinical and fundus manifestations in patients with new onset or acute exacerbation of chronic hypertension. (14651165)
2003
24
Bilateral renal artery stenosis presenting as hypertensive retinopathy and choroidopathy. (12355701)
2002
25
Is leptin associated with hypertensive retinopathy? (10690876)
2000
26
Reversible hypertensive retinopathy in a child with bilateral pheochromocytoma after tumor resection. (11155750)
2000
27
Dramatic regression of hypertensive retinopathy following renal transplantation: a case report. (9595099)
1998
28
Hypertensive retinopathy mimicking neuroretinitis in a twelve-year-old girl. (9220570)
1997
29
Hypertensive retinopathy simulating Leber idiopathic stellate neuroretinitis. (9400800)
1997
30
Hypertensive retinopathy: a review of existing classification systems and a suggestion for a simplified grading system. (8867562)
1996
31
Hypertensive retinopathy: a cause of decreased visual acuity in children. (1432515)
1992
32
Hypertensive retinopathy caused by a rare ovarian tumor: case report and photo essay. (1814990)
1991
33
Cicletanine and hypertensive retinopathy. (2090985)
1990
34
Hypertensive retinopathy. (6544301)
1983
35
Hypertensive retinopathy and generalized scleroderma. (7325205)
1981
36
Hypertensive retinopathy in renovascular hypertension. (7360168)
1980
37
Pathogenesis of hypertensive retinopathy: a review. (399635)
1979
38
The regression of hypertensive retinopathy. (649917)
1978
39
Reversible hypertensive retinopathy. (301240)
1977
40
Pathogenesis of hypertensive retinopathy. An experimental study in the monkey. (804913)
1975
41
Editorial: Hypertensive retinopathy. (807893)
1975
42
Role of local factors in hypertensive retinopathy. (4461687)
1974
43
Experimental hypertensive retinopathy: ultrastructure. (4998607)
1971
44
The rarity of hypertensive retinopathy in the African. (5672739)
1968
45
CHOKED DISC OR HYPERTENSIVE RETINOPATHY IV? (14213922)
1964
46
THE PATHOLOGY OF COTTON WOOL SPOTS AND CYTOID BODIES IN HYPERTENSIVE RETINOPATHY AND OTHER DISEASES. (14123190)
1963
47
The treatment of hypertensive retinopathy. (13339163)
1956
48
Hypertensive retinopathy and its medical treatment. (13215778)
1954
49
Diabetic and hypertensive retinopathy. (14888036)
1951
50
Hypertensive retinopathy in a girl aged 10 years 11 months. (21001842)
1946

Variations for Hypertensive Retinopathy

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Expression for genes affiliated with Hypertensive Retinopathy

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Expression patterns in normal tissues for genes affiliated with Hypertensive Retinopathy

Search GEO for disease gene expression data for Hypertensive Retinopathy.

Pathways for genes affiliated with Hypertensive Retinopathy

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Compounds for genes affiliated with Hypertensive Retinopathy

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Compounds related to Hypertensive Retinopathy according to GeneCards/GeneDecks:

(show top 50)    (show all 51)
idCompoundScoreTop Affiliating Genes
1olmesartan44 28 1111.8ADIPOQ, ACE
2metoprolol44 50 28 24 1113.8ACE, ADIPOQ
3metformin44 50 1111.7ACE, ADIPOQ
4pravastatin44 50 28 24 1113.6ACE, ADIPOQ
5atorvastatin44 50 28 24 1113.6ACE, ADIPOQ
6aopp449.6ALB, ADIPOQ
7halothane44 50 28 1112.6FTH1, ALB
8gliclazide44 50 1111.5ADIPOQ, ALB
9nifedipine44 28 50 1112.5ACE, ADIPOQ
10saquinavir44 1110.5ADIPOQ, ALB
11rosuvastatin44 50 28 1112.5ALB, ADIPOQ
1225-hydroxyvitamin d449.5ALB, ADIPOQ
13olanzapine44 50 28 24 1113.5ADIPOQ, ALB
14indapamide44 1110.5ACE, ALB
15fosinopril44 1110.5ACE, ALB
16uric acid44 2410.5ALB, ADIPOQ
17mannitol44 1110.5ALB, FTH1
18lisinopril44 50 24 1112.5ALB, ACE
19zidovudine44 50 1111.4ADIPOQ, ALB
20perindopril44 50 1111.4ALB, ACE
21hydrochlorothiazide44 28 50 24 1113.4ALB, ACE
22spironolactone44 61 28 50 1113.4ALB, ACE
23estrone44 28 24 1112.4ALB, ADIPOQ
24palmitate449.4ADIPOQ, ALB
25furosemide44 61 28 50 24 1114.4ACE, ALB
26homocysteine44 2410.4ALB, ADIPOQ
27captopril44 61 50 28 1113.4ALB, ACE
28warfarin44 50 24 1112.4ALB, ACE
29kininogen449.4ALB, ACE
30rosiglitazone28 44 50 24 1113.4ADIPOQ, ALB
31prostacyclin449.3ADIPOQ, ACE
32aspirin44 50 28 2412.3ACE, ADIPOQ
33citrate449.3ALB, ADIPOQ
34thyroxine44 2410.2ALB, ADIPOQ
35folate449.2ALB, ADIPOQ
36ascorbic acid44 2410.1ALB, FTH1, ADIPOQ
37tacrolimus44 50 1111.0ALB, ADIPOQ
38ramipril44 1110.0ALB, ACE, ADIPOQ
39valsartan44 61 28 1112.0ADIPOQ, ACE, ALB
40telmisartan44 28 1111.0ALB, ACE, ADIPOQ
41irbesartan44 28 50 1112.0ADIPOQ, ACE, ALB
42candesartan44 50 28 1112.0ALB, ACE, ADIPOQ
43amlodipine44 50 24 1112.0ADIPOQ, ACE, ALB
44enalapril44 50 1110.9ADIPOQ, ACE, ALB
45losartan44 50 28 1111.9ALB, ACE, ADIPOQ
46creatinine448.9ALB, ACE, ADIPOQ
47cholesterol44 28 24 1111.8ALB, ACE, ADIPOQ
48vitamin a44 24 1110.8ALB, ADIPOQ
49glucose448.7ADIPOQ, ACE, ALB
50lipid448.5ADIPOQ, FTH1, ACE, ALB

GO Terms for genes affiliated with Hypertensive Retinopathy

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Cellular components related to Hypertensive Retinopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.5ALB, ACE, ADIPOQ

Biological processes related to Hypertensive Retinopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to nutrientGO:0075849.1ALB, ADIPOQ

Molecular functions related to Hypertensive Retinopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1drug bindingGO:0081448.7ALB, ACE
2protein bindingGO:0055157.5ALB, ACE, FTH1, PSMD9, ADIPOQ

Products for genes affiliated with Hypertensive Retinopathy

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Sources for Hypertensive Retinopathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet