MCID: HYP076
MIFTS: 55

Hyperthyroidism malady

Categories: Endocrine diseases, Rare diseases, Immune diseases, Genetic diseases

Aliases & Classifications for Hyperthyroidism

Aliases & Descriptions for Hyperthyroidism:

Name: Hyperthyroidism 12 29 52 41 42 14 69
Overactive Thyroid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7998
ICD10 33 E05.9
MeSH 42 D006980
NCIt 47 C3123
UMLS 69 C0020550

Summaries for Hyperthyroidism

MedlinePlus : 41 your thyroid is a butterfly-shaped gland in your neck, just above your collarbone. it is one of your endocrine glands, which make hormones. thyroid hormones control the rate of many activities in your body. these include how fast you burn calories and how fast your heart beats. all of these activities are your body's metabolism. if your thyroid is too active, it makes more thyroid hormones than your body needs. this is called hyperthyroidism. hyperthyroidism is more common in women, people with other thyroid problems, and those over 60 years old. graves' disease, an autoimmune disorder, is the most common cause. other causes include thyroid nodules, thyroiditis, consuming too much iodine, and taking too much synthetic thyroid hormone. the symptoms can vary from person to person. they may include being nervous or irritable mood swings fatigue or muscle weakness heat intolerance trouble sleeping hand tremors rapid and irregular heartbeat frequent bowel movements or diarrhea weight loss goiter, which is an enlarged thyroid that may cause the neck to look swollen to diagnose hyperthyroidism, your doctor will do a physical exam, look at your symptoms, and do thyroid tests. treatment is with medicines, radioiodine therapy, or thyroid surgery. no single treatment works for everyone. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Hyperthyroidism, also known as overactive thyroid, is related to hyperthyroidism, familial gestational and gastrinoma. An important gene associated with Hyperthyroidism is TSHR (Thyroid Stimulating Hormone Receptor), and among its related pathways/superpathways are Peptide ligand-binding receptors and Allograft rejection. The drugs Propylthiouracil and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include thyroid, heart and bone, and related phenotypes are Increased HPV16-GFP infection and endocrine/exocrine gland

Disease Ontology : 12 A thyroid gland disease that involves an over production of thyroid hormone.

Wikipedia : 71 Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormone by the... more...

Related Diseases for Hyperthyroidism

Diseases in the Hyperthyroidism family:

Familial Hyperthyroidism Due to Mutations in Tsh Receptor

Diseases related to Hyperthyroidism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 319)
id Related Disease Score Top Affiliating Genes
1 hyperthyroidism, familial gestational 33.9 GNAS TSHR
2 gastrinoma 29.5 TG TSHR
3 endemic goiter 29.2 BGLAP SERPINA7 SHBG TG TPO TSHR
4 primary biliary cirrhosis 29.1 GHRL LEP PRL SHBG
5 hyperthyroidism, nonautoimmune 12.3
6 graves' disease 11.9
7 familial hyperthyroidism due to mutations in tsh receptor 11.9
8 congenital craniosynostosis maternal hyperthyroiditis 11.8
9 thyroid hormone resistance, selective pituitary 11.5
10 thyroid crisis 11.1
11 hypothyroidism 11.1
12 struma ovarii 11.0
13 myxedema 11.0
14 thyrotoxic periodic paralysis 1 11.0
15 pituitary tumors 11.0
16 hypoparathyroidism 11.0
17 myopathy - thyrotoxic 11.0
18 thyrotoxic periodic paralysis 2 10.8
19 mccune-albright syndrome, somatic, mosaic 10.8
20 hypobetalipoproteinemia, familial, 2 10.7
21 autoimmune thyroid disease 3 10.7
22 brugada syndrome 7 10.7
23 hypolipoproteinemia 10.7
24 superior limbic keratoconjunctivitis 10.7
25 thyrotoxic periodic paralysis 10.7
26 hyperthyroxinemia, familial dysalbuminemic 10.7
27 thyroiditis 10.5
28 fibrous meningioma 10.3 TG TPO
29 neuhauser daly magnelli syndrome 10.3 TG TPO TSHR
30 neonatal thyrotoxicosis 10.3
31 neuronopathy, distal hereditary motor, type viia 10.3 SERPINA7 TG TSHR
32 nodular prostate 10.3 TG TPO TSHR
33 peritoneal serous papillary adenocarcinoma 10.3 TG TPO TSHR
34 commensal bacterial infectious disease 10.3 TG TPO TSHR
35 acute hemorrhagic encephalitis 10.3 TG TSHR
36 choreoathetosis, hypothyroidism, and neonatal respiratory distress 10.3 TG TPO TSHR
37 tenosynovitis of foot and ankle 10.2 TG TPO TSHR
38 conjunctival deposit 10.2 CTLA4 TG TPO TSHR
39 background diabetic retinopathy 10.2 SERPINA7 TG TPO TSHR
40 krabbe disease 10.2 SERPINA7 TG TPO TSHR
41 denys-drash syndrome 10.2 CTLA4 TG TPO TSHR
42 congenital nonspherocytic hemolytic anemia 10.2 SERPINA7 TPO TRH
43 atheroembolism of kidney 10.2 TG TRH
44 diabetes mellitus, insulin-dependent, 12 10.2 CTLA4 TG TPO TSHR
45 color blindness 10.2 SST TG TPO
46 mesocardia 10.2 TG TSHR
47 plummer's disease 10.2
48 premature closure of the arterial duct 10.2 TG TPO
49 exanthema subitum 10.2 GNAS TG TPO TSHR
50 non-distal monosomy 10q 10.2 BGLAP TG TPO TSHR

Graphical network of the top 20 diseases related to Hyperthyroidism:



Diseases related to Hyperthyroidism

Symptoms & Phenotypes for Hyperthyroidism

GenomeRNAi Phenotypes related to Hyperthyroidism according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased HPV16-GFP infection GR00350-A 8.92 GNAS SDHA SERPINA7 TRH

MGI Mouse Phenotypes related to Hyperthyroidism:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.9 CGA CTLA4 GHRL GNAS LEP PRL
2 homeostasis/metabolism MP:0005376 9.8 CGA CTLA4 GHRL GNAS LEP PRL
3 immune system MP:0005387 9.32 PRL PRTN3 SERPINA6 SST THRB TPO

Drugs & Therapeutics for Hyperthyroidism

Drugs for Hyperthyroidism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 232)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propylthiouracil Approved Phase 4,Phase 3,Phase 2 51-52-5 657298
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
4
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 53-03-2 5865
5
Bimatoprost Approved, Investigational Phase 4,Phase 3 155206-00-1 5311027
6
Latanoprost Approved, Investigational Phase 4 130209-82-4 5282380 5311221
7
Timolol Approved Phase 4 26839-75-8 33624 5478
8
Travoprost Approved Phase 4 157283-68-6 5282226
9
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
10
Acetylcholine Approved Phase 4,Phase 2,Phase 3 51-84-3 187
11
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 1 50-02-2 5743
12
Dinoprost Tromethamine Approved, Vet_approved Phase 4 38562-01-5 5282415
13
Ephedrine Approved Phase 4,Phase 2 299-42-3 9294
14
Pseudoephedrine Approved Phase 4,Phase 2 90-82-4 7028
15
Diclofenac Approved, Vet_approved Phase 4,Phase 3 15307-86-5 3033
16
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
17
Propranolol Approved, Investigational Phase 4 525-66-6 4946
18
Methotrexate Approved Phase 4 1959-05-2, 59-05-2 126941
19
rituximab Approved Phase 4,Phase 2,Phase 3,Phase 1 174722-31-7 10201696
20
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
21
Alfacalcidol Approved, Nutraceutical Phase 4,Phase 2 41294-56-8 5282181
22
Calcitriol Approved, Nutraceutical Phase 4 32222-06-3 134070 5280453
23
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
24
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 59-30-3 6037
25
leucovorin Approved, Nutraceutical Phase 4 58-05-9 54575, 6560146 143
26
Maleic acid Experimental Phase 4 110-16-7 444266
27 Antimetabolites Phase 4,Phase 3,Phase 2
28 Antithyroid Agents Phase 4,Phase 3,Phase 1,Phase 2
29 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
30 Hormones Phase 4,Phase 2,Phase 3,Phase 1
31 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
32 Antiemetics Phase 4,Phase 2,Phase 3,Phase 1
33 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
34 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
35 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1
36 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
37 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
38 Methylprednisolone acetate Phase 4,Phase 2,Phase 3
39 Methylprednisolone Hemisuccinate Phase 4,Phase 2,Phase 3
40 Neuroprotective Agents Phase 4,Phase 2,Phase 3
41 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1
42 Prednisolone acetate Phase 4,Phase 2,Phase 3
43 Prednisolone hemisuccinate Phase 4,Phase 2,Phase 3
44 Prednisolone phosphate Phase 4,Phase 2,Phase 3
45 Protective Agents Phase 4,Phase 2,Phase 3
46 Adrenergic Agents Phase 4,Phase 2
47 Adrenergic Antagonists Phase 4
48 Adrenergic beta-Antagonists Phase 4
49 Anti-Arrhythmia Agents Phase 4
50 Antihypertensive Agents Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 172)
id Name Status NCT ID Phase
1 Treatment of Subclinical Hyperthyroidism Unknown status NCT00213720 Phase 4
2 Assessment of Intellectual, Psychological and Behavioural Developments Between 6 and 9 Years of the Children Born to Hyperthyroid Mothers During Their Pregnancy Unknown status NCT01779817 Phase 4
3 The Effect of Early Total Thyroidectomy in the Course of Graves' Orbitopathy Unknown status NCT01056419 Phase 4
4 A Prospective, Randomized Trial of Intravenous Pulse Versus Sequential Steroid Therapy for Patients With Graves' Orbitopathy Unknown status NCT01969019 Phase 4
5 The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients. Unknown status NCT01927406 Phase 4
6 Block-replacement Therapy During Radioiodine Therapy Completed NCT00150124 Phase 4
7 Antithyroid Drugs During Radioiodine Therapy Completed NCT00150137 Phase 4
8 Impact of SSKI Pre-Treatment on Blood Loss in Thyroidectomy for Graves Disease Completed NCT00946296 Phase 4
9 Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasone Completed NCT00917241 Phase 4
10 Effect of Hormone Replacement Therapy on Lupus Activity Completed NCT00392093 Phase 4
11 Compare the Efficacy of Cinacalcet vs Traditional Vitamin D for Secondary Hyperparathyroidism (SHPT) Among Subjects Undergoing Hemodialysis Completed NCT01181531 Phase 4
12 Prostaglandin F2-alpha Eye Drops in Thyroid Eye Disease (Bima Study) Completed NCT02059655 Phase 4
13 Treatment of Upper Eyelid Retraction Related to Thyroid-associated Ophthalmopathy Using Subconjunctival Triamcinolone Injections Completed NCT01599273 Phase 4
14 Adjuvant Treatment of Graves´ Ophthalmopathy With NSAID (aGO Study) Completed NCT01458600 Phase 4
15 Is the Routine Pressure Dressing After Thyroidectomy Necessary? Completed NCT00400465 Phase 4
16 Levothyroxine Replacement for Subclinical Hypothyroidism and Chronic Heart Failure Recruiting NCT03096613 Phase 4
17 Using A Novel Classification System in Intravenous GCs Therapy of TAO: A Multi-central, Randomized, Open, Superior Trial Recruiting NCT03107078 Phase 4
18 Rituximab (RTX) Therapy in Patients With Active TAO Recruiting NCT02378298 Phase 4
19 Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease Recruiting NCT01738243 Phase 4
20 Effects of Statins in Graves' Orbitopathy (GO) in Hypercholesterolemic Patients Not yet recruiting NCT03110848 Phase 4
21 A Trial to Evaluate the Efficacy of Orbital Radiotherapy in Graves' Orbitopathy Not yet recruiting NCT03098225 Phase 4
22 Combined Radiotherapy and Intravenous Steroids for Early Progressive Thyroid Eye Disease Not yet recruiting NCT02339142 Phase 4
23 Use of Botox in the Management of Thyroid Related Upper Eyelid Retraction Withdrawn NCT01272414 Phase 4
24 Treatment of Soft Tissue Expansion in Inactive Thyroid Eye Disease Patients Using Drops of Prostaglandin Analogues Unknown status NCT02155049 Phase 3
25 Prednisone Versus Doxycycline in the Treatment of Graves' Orbitopathy Unknown status NCT01809444 Phase 2, Phase 3
26 Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye Disease Unknown status NCT00370734 Phase 2, Phase 3
27 Comparison of Different Doses of 131I in Severe Graves' Hyperthyroidism Completed NCT01039818 Phase 3
28 Early Administration of L-carnitine in Hemodialysis Patients Completed NCT00322322 Phase 3
29 Low Salt Diet in Idiopathic Hypercalciuria Completed NCT01005082 Phase 2, Phase 3
30 Percutaneous Radiofrequency Thermal Ablation in Compressive Thyroid Nodules Completed NCT01649206 Phase 3
31 Antithyroid Drug Treatment of Thyrotoxicosis in Young People Completed NCT01436994 Phase 3
32 Tocilizumab Treatment in Graves´ Ophthalmopathy (Graves´ Orbitopathy or Thyroid Eye Disease) Completed NCT01297699 Phase 3
33 Assessing the Impact of the Early and Systematic Hormonal Replacement After Radio-isotopic Ablation of Graves'hyperthyroïdism on Quality of Life, Efficiency and Tolerance Completed NCT01295333 Phase 3
34 Trial of Rituximab for Graves' Ophthalmopathy Completed NCT00595335 Phase 2, Phase 3
35 Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathy Recruiting NCT03066076 Phase 3
36 Bupivacaine Injection of Eye Muscles to Treat Strabismus Recruiting NCT01616108 Phase 2, Phase 3
37 The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated Ophthalmopathy Recruiting NCT01579539 Phase 3
38 Early Levothyroxine Post Radioactive Iodine Active, not recruiting NCT01950260 Phase 2, Phase 3
39 Treatment of Graves´Ophthalmopathy With Diclofenac or Simvastatin (GO-DS) Not yet recruiting NCT03131726 Phase 3
40 The Effect of a New Antioxidant Combination (ASTED) on Moderate to Severe Thyroid Eye Disease Not yet recruiting NCT02422368 Phase 2, Phase 3
41 The Effect of a New Antioxidant Combination (ASTED) on Mild Thyroid Eye Disease (TED) Not yet recruiting NCT02393183 Phase 2, Phase 3
42 Role of the Microbiome in Graves' Orbitopathy Unknown status NCT02373995 Phase 1, Phase 2
43 Doxycycline Treatment in Mild Graves' Orbitopathy Unknown status NCT02203682 Phase 2
44 LDL-Cholesterol Lowering Effect of KB2115 as Add on to Statin Completed NCT00593047 Phase 2
45 rhTSH, Thyroid Size, and Radioiodine Therapy in Benign Goiter Completed NCT00145366 Phase 2
46 Eprotirome for the Treatment of Dyslipidemia, Efficacy and Safety 12-Week, Phase ii Study to Assess the Safety and Efficacy of KB2115 in Patients With Primary Hypercholesterolemia Completed NCT00776321 Phase 2
47 LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe Completed NCT00677248 Phase 2
48 Can Oral T3 Normalize Thyroid Hormone Levels Following Cardiopulmonary Bypass in Children? Completed NCT01780584 Phase 2
49 A Study to Evaluate the Safety and Effect of CFZ533 on Patients With Graves' Disease Completed NCT02713256 Phase 2
50 Radioactive Iodide Therapy for Pediatric Graves' Disease Completed NCT01269749 Phase 2

Search NIH Clinical Center for Hyperthyroidism

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: hyperthyroidism

Genetic Tests for Hyperthyroidism

Genetic tests related to Hyperthyroidism:

id Genetic test Affiliating Genes
1 Hyperthyroidism 29

Anatomical Context for Hyperthyroidism

MalaCards organs/tissues related to Hyperthyroidism:

39
Thyroid, Heart, Bone, Testes, Kidney, Pituitary, Brain

Publications for Hyperthyroidism

Articles related to Hyperthyroidism:

(show top 50) (show all 1163)
id Title Authors Year
1
Comparative Effectiveness of Treatment Choices for Graves' Hyperthyroidism - A Historical Cohort Study. ( 28049375 )
2017
2
Dyschromatosis symmetrica hereditaria with cutaneous lupus erythematosus and hyperthyroidism. ( 28496371 )
2017
3
Hypokalemic Paralysis Complicated by Concurrent Hyperthyroidism and Hyperaldosternoism: A Case Report. ( 28050008 )
2017
4
Clinical efficacy of Yingliu mixture combined with metimazole for treating diffuse goitre with hyperthyroidism and its impact on related cytokines. ( 27927064 )
2017
5
Effects of electromagnetic fields on bone loss in hyperthyroidism rat model. ( 27973686 )
2017
6
Effect of Hypothyroidism and Hyperthyroidism on Tissue Thyroid Hormone Concentrations in Rat. ( 27099836 )
2016
7
2016 AAFP Guidelines for the Management of Feline Hyperthyroidism. ( 27143042 )
2016
8
The effect of preoperative Lugol's iodine on intraoperative bleeding in patients with hyperthyroidism. ( 27408715 )
2016
9
2016 AAFP Guidelines for the Management of Feline Hyperthyroidism. ( 27562983 )
2016
10
Effect of hyperthyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat. ( 27919641 )
2016
11
EVALUATION OF QUANTITATIVE THYROID SCINTIGRAPHY FOR DIAGNOSIS AND STAGING OF DISEASE SEVERITY IN CATS WITH HYPERTHYROIDISM: COMPARISON OF THE PERCENT THYROIDAL UPTAKE OF PERTECHNETATE TO THYROID-TO-SALIVARY RATIO AND THYROID-TO-BACKGROUND RATIOS. ( 27062212 )
2016
12
Hyperthyroidism and Graves' disease: Is an ultrasound examination needed? ( 27867894 )
2016
13
Abnormal brain functional connectivity leads to impaired mood and cognition in hyperthyroidism: a resting-state functional MRI study. ( 28009983 )
2016
14
Graves' hyperthyroidism accompanied with acute hepatitis B virus infection: an extrahepatic manifestation? ( 27206523 )
2016
15
HYPERTHYROIDISM AND HYPERPROLACTINEMIA, IS THERE ANY ASSOCIATION? ( 27540882 )
2016
16
Bleeding heart: a case of spontaneous hemopericardium and tamponade in a hyperthyroid patient on warfarin. ( 27413023 )
2016
17
Changes in profile of lipids and adipokines in patients with newly diagnosed hypothyroidism and hyperthyroidism. ( 27193069 )
2016
18
Concurrent hyperthyroidism and papillary thyroid cancer: a fortuitous and ambiguous case report from a resource-poor setting. ( 27461263 )
2016
19
Hyperthyroidism Improves the Pathological Condition of Nonalcoholic Steatohepatitis: A Case of Nonalcoholic Steatohepatitis with Graves' Disease. ( 27477408 )
2016
20
Choriocarcinoma as a cause of hyperthyroidism. ( 28011852 )
2016
21
Cholestyramine as monotherapy for Graves' hyperthyroidism. ( 27872940 )
2016
22
Takotsubo Cardiomyopathy Associated with Primary Hyperthyroidism Secondary to Toxic Multinodular Goiter. ( 28031674 )
2016
23
Systemic lupus erythematosus and renal tubular acidosis associated with hyperthyroidism. Case Report. ( 27179580 )
2016
24
A meta-analysis of the association of serum ischemia-modified albumin levels withA human hypothyroidism and hyperthyroidism. ( 27920278 )
2016
25
Serum Levels of Follistatin Are Positively Associated With Serum-Free Thyroxine Levels in Patients With Hyperthyroidism or Euthyroidism. ( 26844494 )
2016
26
Management of hyperthyroidism due to Graves' disease: frequently asked questions and answers (if any). ( 27319009 )
2016
27
The Hypercoagulable state in Hyperthyroidism is mediated via the Thyroid Hormone I^ Receptor pathway. ( 26961801 )
2016
28
Surgical Intervention for Medically Refractory Hyperthyroidism. ( 27171805 )
2016
29
Hyperdynamic Right Heart Function in Graves' Hyperthyroidism Measured by Echocardiography Normalises on Restoration of Euthyroidism. ( 28025026 )
2016
30
Total thyroidectomy: a clue to understanding the metabolic changes induced by subclinical hyperthyroidism? ( 27651121 )
2016
31
Hyperthyroidism and Thyroid Carcinoma. ( 27930273 )
2016
32
The Natural History of Subclinical Hyperthyroidism in Graves' Disease: The Rule of Thirds. ( 27090092 )
2016
33
Parathyroid Hormone Polymorphism RS6254 is Associated with the Development and Severity of Osteoporosis in Asymptomatic but not Normocalcemic Hyperthyroidism. ( 27756092 )
2016
34
Antithyroid Drugs for Hyperthyroidism. ( 27044129 )
2016
35
A caution regarding high-dose biotin therapy: misdiagnosis of hyperthyroidism in euthyroid patients. ( 27510354 )
2016
36
A Case Report of Chorea Associated with Hyperthyroidism. ( 27042533 )
2016
37
Low-dose spinal-epidural anesthesia for Cesarean section in a parturient with uncontrolled hyperthyroidism and thyrotoxic heart disease. ( 27216206 )
2016
38
Quality-of-Life Impairments Persist Six Months After Treatment of Graves' Hyperthyroidism and Toxic Nodular Goiter: A Prospective Cohort Study. ( 27370744 )
2016
39
Effect of Selenium Supplementation on Recurrent Hyperthyroidism Caused by Graves' Disease: A Prospective Pilot Study. ( 27392116 )
2016
40
Efficacy of protocols for induction of chronic hyperthyroidism in male and female mice. ( 27473100 )
2016
41
Subclinical hyperthyroidism: First do no harm. ( 27028121 )
2016
42
Evaluation of endothelial function in exogenous subclinical hyperthyroidism and the effect of treatment. ( 28028513 )
2016
43
Advanced glycation end products (AGEs) and its receptors in the pathogenesis of hyperthyroidism. ( 26895319 )
2016
44
Serum Cystatin C Concentrations in Cats with Hyperthyroidism and Chronic Kidney Disease. ( 27155206 )
2016
45
Sex-specific phenotypes of hyperthyroidism and hypothyroidism in mice. ( 27559466 )
2016
46
The Influence of Antithyroid Drug Discontinuation to the Therapeutic Efficacy of (131)I in Hyperthyroidism. ( 27134556 )
2016
47
A 33-Year-Old Man with Gynaecomastia and Galactorrhea as the First Symptoms of Graves Hyperthyroidism. ( 28044109 )
2016
48
Hyperthyroidism Caused By Thyroid Hormone Therapy. ( 27929219 )
2016
49
Differential Hepatic Gene Expression Profile and Histone Modification After Acute or Chronic Hyperthyroidism or During Remission. ( 27035771 )
2016
50
An autopsy case of hyperthyroid cardiomyopathy manifesting lethal congestive heart failure. ( 28008703 )
2016

Variations for Hyperthyroidism

Expression for Hyperthyroidism

Search GEO for disease gene expression data for Hyperthyroidism.

Pathways for Hyperthyroidism

Pathways related to Hyperthyroidism according to GeneCards Suite gene sharing:

(show all 11)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.12 CGA GH1 GHRL GNAS LEP PRL
2
Show member pathways
12.62 CGA CTLA4 TG TPO TSHR
3
Show member pathways
12.25 CGA GH1 LEP PRL
4
Show member pathways
11.93 CGA GH1 GHRL LEP
5
Show member pathways
11.83 CGA GNAS SERPINA7 TG TPO TSHR
6 11.52 BGLAP CGA PRL
7 11.41 CGA GNAS TSHR
8 11.23 CGA GNAS TSHR
9 11.09 BGLAP CGA THRB
10 10.57 CGA TSHR
11 9.8 CGA TG TPO TRH TSHR

GO Terms for Hyperthyroidism

Cellular components related to Hyperthyroidism according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 BGLAP GH1 GHRL LEP PRTN3 SERPINA6
2 extracellular region GO:0005576 9.47 BGLAP CGA GH1 GHRL GNAS LEP
3 endosome lumen GO:0031904 9.16 GH1 PRL

Biological processes related to Hyperthyroidism according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.85 CGA LEP PRL PRTN3 TSHR
2 cell-cell signaling GO:0007267 9.84 CGA SST TRH TSHR
3 response to estradiol GO:0032355 9.7 GH1 LEP PRL
4 female pregnancy GO:0007565 9.65 GNAS LEP PRL
5 response to nutrient GO:0007584 9.54 LEP PRL SST
6 energy reserve metabolic process GO:0006112 9.51 GNAS LEP
7 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.49 GH1 PRL
8 response to ethanol GO:0045471 9.46 BGLAP LEP PRL TRH
9 thyroid hormone generation GO:0006590 9.43 CGA TPO
10 positive regulation of multicellular organism growth GO:0040018 9.43 GH1 GHRL TSHR
11 hormone biosynthetic process GO:0042446 9.4 TG TPO
12 adult feeding behavior GO:0008343 9.32 GHRL LEP
13 hormone-mediated signaling pathway GO:0009755 9.13 GHRL TRH TSHR
14 positive regulation of JAK-STAT cascade GO:0046427 8.8 GH1 LEP PRL

Molecular functions related to Hyperthyroidism according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.23 CGA GH1 GHRL LEP PRL SST
2 prolactin receptor binding GO:0005148 8.96 GH1 PRL

Sources for Hyperthyroidism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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