MCID: HYP061
MIFTS: 61

Hypertrophic Cardiomyopathy malady

Cardiovascular diseases category

Summaries for Hypertrophic Cardiomyopathy

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63Wikipedia, 46OMIM, 19GeneReviews, 32MalaCards
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Wikipedia:63 Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in... more...

MalaCards: Hypertrophic Cardiomyopathy, also known as hypertrophic obstructive cardiomyopathy, is related to familial hypertrophic cardiomyopathy and dilated cardiomyopathy. An important gene associated with Hypertrophic Cardiomyopathy is MYH7 (myosin, heavy chain 7, cardiac muscle, beta), and among its related pathways are Hypertrophic cardiomyopathy (HCM) and Striated Muscle Contraction. The compounds calcium and creatinine have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and brain, and related mouse phenotypes are muscle and mortality/aging.

Description from OMIM:46 192600

GeneReviews summary for hyper-card

Aliases & Classifications for Hypertrophic Cardiomyopathy

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8Disease Ontology, 19GeneReviews, 10DISEASES, 60UMLS, 44Novoseek, 56SNOMED-CT, 34MeSH, 39NCIt, 46OMIM, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

hypertrophic cardiomyopathy 8 19 10 60
hypertrophic obstructive cardiomyopathy 8
cardiomyopathy hypertrophic obstructive 44
primary hypertrophic cardiomyopathy 8
cardiomyopathy, hypertrophic 8
hyper. obst. cardiomyopathy 8
hypertrophic myocardiopathy 8


External Ids:

Disease Ontology8 DOID:11984
MeSH34 D002312
NCIt39 C34449
OMIM46 192600
ICD9CM27 425.1
ICD1025 I42.1

Related Diseases for Hypertrophic Cardiomyopathy

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17GeneCards, 18GeneDecks
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Diseases in the Familial Hypertrophic Cardiomyopathy family:

hypertrophic cardiomyopathy Cav3-Related Hypertrophic Cardiomyopathy
Myh7-Related Familial Hypertrophic Cardiomyopathy Tnnt2-Related Familial Hypertrophic Cardiomyopathy
Tpm1-Related Familial Hypertrophic Cardiomyopathy Mybpc3-Related Familial Hypertrophic Cardiomyopathy
Tnni3-Related Familial Hypertrophic Cardiomyopathy Myl3-Related Familial Hypertrophic Cardiomyopathy
Myl2-Related Familial Hypertrophic Cardiomyopathy Ttn-Related Familial Hypertrophic Cardiomyopathy
Actc1-Related Familial Hypertrophic Cardiomyopathy Myh6-Related Familial Hypertrophic Cardiomyopathy
Tcap-Related Familial Hypertrophic Cardiomyopathy Csrp3-Related Familial Hypertrophic Cardiomyopathy
Tnnc1-Related Familial Hypertrophic Cardiomyopathy Actn2-Related Familial Hypertrophic Cardiomyopathy
Myoz2-Related Familial Hypertrophic Cardiomyopathy Nexn-Related Familial Hypertrophic Cardiomyopathy
Pln-Related Familial Hypertrophic Cardiomyopathy Cardiomyopathy, Familial Hypertrophic, 20
Cardiomyopathy, Familial Hypertrophic, 2 Cardiomyopathy, Familial Hypertrophic, 9
Cardiomyopathy, Familial Hypertrophic, 13 Cardiomyopathy, Familial Hypertrophic, 8
Cardiomyopathy, Familial Hypertrophic, 16 Cardiomyopathy, Familial Hypertrophic, 18
Cardiomyopathy, Familial Hypertrophic, 21 Cardiomyopathy, Familial Hypertrophic 6
Cardiomyopathy, Familial Hypertrophic, 15 Cardiomyopathy, Familial Hypertrophic, 12
Cardiomyopathy, Familial Hypertrophic, 4 Cardiomyopathy, Familial Hypertrophic, 10
Cardiomyopathy, Familial Hypertrophic, 14 Cardiomyopathy, Familial Hypertrophic, 1
Cardiomyopathy, Familial Hypertrophic, 11 Cardiomyopathy, Familial Hypertrophic, 3
Cardiomyopathy, Familial Hypertrophic, 19 Cardiomyopathy, Familial Hypertrophic, 7
Cardiomyopathy, Familial Hypertrophic 17 Hypertrophic Cardiomyopathy Due to Intensive Athletic Training

Diseases related to Hypertrophic Cardiomyopathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 295)
idRelated DiseaseScoreTop Affiliating Genes
1familial hypertrophic cardiomyopathy31.9CALR3, CSRP3, TNNT2, TPM1, ACTC1, TNNI3
2dilated cardiomyopathy31.0MYBPC2, MYH6, MYBPC3, MYH7, TTN, PLN
3noonan syndrome30.9TCAP, SLC25A4, PLN, TTN, MYH7, MYBPC3
4myopathy30.8MYOZ2, TNNT2, TNNI3, MYH6, MYH7, TTN
5myocardial infarction30.7MYL3, TNNI3, TNNT2
6nemaline myopathy30.6ACTC1
7myocarditis30.5MYH6, TNNT2, TNNI3
8acute myocardial infarction30.3MYH7, TNNT2, TNNI3, MYL3
9congestive heart failure30.3TNNI3, TNNT2
10ischemia30.3TTN, MYH7, TNNT2
11myotonic dystrophy30.2MYH7
12diastolic heart failure30.2TTN
13hypertension10.7
14alcoholic cardiomyopathy10.6
15hypertensive heart disease10.6
16leopard syndrome10.4
17fabry disease10.4
18wolff-parkinson-white syndrome10.4
19long qt syndrome10.4
20costello syndrome10.3
21glycogen storage disease10.3
22fatal infantile hypertrophic cardiomyopathy due to mitochondrial complex i deficiency10.3
23angiodysplasia10.3
24friedreich ataxia10.3
25danon disease10.3
26ventricular septal defect10.3
27deafness, autosomal dominant 2210.3
28cardiac tamponade10.2
29mitral valve prolapse10.2
30cardiac sarcoidosis10.2
31tetralogy of fallot10.2
32myocardial stunning10.2
33septal myocardial infarction10.2
34acute myocarditis10.2
35congenital disorder of glycosylation10.2
36endocarditis10.2
37lactic acidosis10.2
38obesity10.2
39sarcoidosis10.2
40combined oxidative phosphorylation deficiency 1010.2
41hypertrophic cardiomyopathy, midventricular, digenic10.2
42mucopolysaccharidosis ih10.2
43maternally-inherited mitochondrial hypertrophic cardiomyopathy10.2
44hypertrophic cardiomyopathy due to intensive athletic training10.2
45hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial dna mutation10.2
46mixed connective tissue disease10.1
47systolic heart failure10.1
48connective tissue disease10.1
49hemolytic anemia10.1
50pheochromocytoma10.1

Graphical network of the top 20 diseases related to Hypertrophic Cardiomyopathy:



Diseases related to hypertrophic cardiomyopathy

Clinical Features for Hypertrophic Cardiomyopathy

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46OMIM
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Clinical features from OMIM:

192600

Drugs & Therapeutics for Hypertrophic Cardiomyopathy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Hypertrophic Cardiomyopathy

Drug clinical trials:

Search ClinicalTrials for Hypertrophic Cardiomyopathy

Search NIH Clinical Center for Hypertrophic Cardiomyopathy

Search CenterWatch for Hypertrophic Cardiomyopathy

Genetic Tests for Hypertrophic Cardiomyopathy

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Anatomical Context for Hypertrophic Cardiomyopathy

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32MalaCards
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MalaCards organs/tissues related to Hypertrophic Cardiomyopathy:

32
Heart, Testes, Brain, Endothelial, Cardiac myocytes, Skeletal muscle, Kidney, Skin, Monocytes, Smooth muscle, Liver

Animal Models for Hypertrophic Cardiomyopathy or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Hypertrophic Cardiomyopathy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000536911.4ACTC1, CSRP3, TNNT2, TNNI3, MYL2, MYOZ2
2MP:001076811.4CSRP3, TNNT2, TNNI3, MYL2, MYOZ2, MYH6
3MP:000538511.4MYOZ2, MYL2, TNNI3, TNNT2, CSRP3, MYH6
4MP:000537611.1MYH6, MYOZ2, MYL2, TNNT2, CSRP3, MYO6

Publications for Hypertrophic Cardiomyopathy

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50PubMed
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Articles related to Hypertrophic Cardiomyopathy:

(show top 50)    (show all 1423)
idTitleAuthorsYear
1
Prevention of sudden cardiac death in hypertrophic cardiomyopathy. (23574968)
2014
2
ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy. (23849775)
2013
3
Catheter ablation of atrial fibrillation in hypertrophic cardiomyopathy: long-term outcomes and mechanisms of arrhythmia recurrence. (24114776)
2013
4
Hypertrophic cardiomyopathy. (24295188)
2013
5
Genetics of hypertrophic cardiomyopathy in Norway. (24111713)
2013
6
Experience, outcomes and impact of delayed indication for video-assisted wide septal myectomy in 69 consecutive patients with hypertrophic cardiomyopathy. (23428579)
2013
7
Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. (23960072)
2013
8
Myocardial fibrosis severity on cardiac magnetic resonance imaging predicts sustained arrhythmic events in hypertrophic cardiomyopathy. (22749647)
2013
9
Hypertrophic cardiomyopathy associated with left ventricular noncompaction cardiomyopathy and coronary fistulae: A case report. One genotype, three phenotypes? (24268868)
2013
10
Correlation of electrocardiographic changes and myocardial fibrosis in patients with hypertrophic cardiomyopathy detected by cardiac magnetic resonance imaging. (23070984)
2013
11
Flail subaortic membrane mimicking left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. (23837119)
2013
12
Prevention of sudden cardiac death with implantable cardioverter-defibrillators in children and adolescents with hypertrophic cardiomyopathy. (23500286)
2013
13
The role of renin-angiotensin-aldosterone system polymorphisms in phenotypic expression of MYBPC3-related hypertrophic cardiomyopathy. (22569109)
2012
14
Myocardial crypts: a prephenotypic marker of hypertrophic cardiomyopathy? (22811415)
2012
15
Obstruction in hypertrophic cardiomyopathy: how often does it occur? Should it be treated? If so, how? (23076969)
2012
16
Reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy. (23259835)
2012
17
An assessment of regression of left ventricular hypertrophy following alcohol ablation of the interventricular septum in patients with hypertrophic cardiomyopathy with left ventricular outflow tract obstruction. (22933209)
2012
18
Hypertrophic cardiomyopathy in a neonate associated with nemaline myopathy. (22067214)
2012
19
Nemaline myopathy and non-fatal hypertrophic cardiomyopathy caused by a novel ACTA1 E239K mutation. (21570694)
2011
20
Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin. (21723297)
2011
21
Hypertrophic Cardiomyopathy in a Young Adult with RV Aneurysm: Report of a Rare Finding and Review of the Literature. (22567198)
2011
22
Hemolytic anemia in a patient with hypertrophic obstructive cardiomyopathy. (20122559)
2010
23
Plasma glycogen phosphorylase BB is associated with pulmonary artery wedge pressure and left ventricle mass index in patients with hypertrophic cardiomyopathy. (20482380)
2010
24
Adiponectin acts as a positive indicator of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy. (19648128)
2010
25
Left atrial volume in children without heart disease and in those with ventricular septal defect or patent ductus arteriosus or hypertrophic cardiomyopathy. (21059443)
2010
26
Myocardial siderosis due to hemochromatosis in an individual with hypertrophic cardiomyopathy. (19960138)
2009
27
Novel MYBPC3 mutations in Chinese patients with hypertrophic cardiomyopathy]. (20021930)
2009
28
Relationship between circulating levels of monocyte chemoattractant protein-1 and systolic dysfunction in patients with hypertrophic cardiomyopathy. (19211266)
2009
29
Diagnostic yield, interpretation, and clinical utility of mutation screening of sarcomere encoding genes in Danish hypertrophic cardiomyopathy patients and relatives. (19035361)
2009
30
Homozygous mutation of MYBPC3 associated with severe infantile hypertrophic cardiomyopathy at high frequency among the Amish. (18467358)
2008
31
Coenzyme Q10 (CoQ10) in isolated diastolic heart failure in hypertrophic cardiomyopathy (HCM). (19096110)
2008
32
Genotype-phenotype correlation of R870H mutation in hypertrophic cardiomyopathy. (16650083)
2006
33
Hypertrophic cardiomyopathy in a Portuguese population: mutations in the myosin-binding protein C gene. (16566405)
2005
34
Familial aggregation of genetically heterogeneous hypertrophic cardiomyopathy: a boy with LEOPARD syndrome due to PTPN11 mutation and his nonsyndromic father lacking PTPN11 mutations. (14991917)
2004
35
Pro-oxidant malonaldehyde and antioxidant ceruloplasmin levels in hypertrophic cardiomyopathy. (15129799)
2004
36
Common pathways for primary hypertrophic and dilated cardiomyopathy. (12713689)
2003
37
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy. (12707239)
2003
38
Systematic analysis of the regulatory and essential myosin light chain genes: genetic variants and mutations in hypertrophic cardiomyopathy. (12404107)
2002
39
Circulating levels of insulin-like growth factor-1 and its binding proteins in patients with hypertrophic cardiomyopathy. (12135130)
2002
40
Coexistence of hypertrophic cardiomyopathy and fibromuscular dysplasia of the superior mesenteric artery. (11336027)
2001
41
Proximal trisomy of 1q mosaicism in a girl with hypertrophic cardiomyopathy associated with Wolff-Parkinson-White syndrome and multiple congenital anomalies. (11343316)
2001
42
Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy. (10966831)
2000
43
Transgenic modeling of a cardiac troponin I mutation linked to familial hypertrophic cardiomyopathy. (11055985)
2000
44
Energetics and function of the failing human heart with dilated or hypertrophic cardiomyopathy. (10354207)
1999
45
Hypertrophic cardiomyopathy in congenital myotonic dystrophy. (9588538)
1998
46
Identification of a mutation near a functional site of the beta cardiac myosin heavy chain gene in a family with hypertrophic cardiomyopathy. (7815466)
1994
47
Mapping of a novel gene for familial hypertrophic cardiomyopathy to chromosome 11. (8358441)
1993
48
Myocardial stunning in hypertrophic cardiomyopathy: recovery predicted by single photon emission computed tomographic thallium-201 scintigraphy. (2784808)
1989
49
Antimitochondrial autoantibodies in myocardial hypertrophy: comparison between hypertrophic cardiomyopathy, hypertensive heart disease, and athlete's heart. (2969669)
1988
50
Familial hypertrophic cardiomyopathy and preexcitation. (6229172)
1984

Genetic Variations for Hypertrophic Cardiomyopathy

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Expression for genes affiliated with Hypertrophic Cardiomyopathy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypertrophic Cardiomyopathy

Search GEO for disease gene expression data for Hypertrophic Cardiomyopathy.

Pathways for genes affiliated with Hypertrophic Cardiomyopathy

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Sources:
29KEGG, 37NCBI BioSystems Database, 53Reactome, 12EMD Millipore, 4Cell Signaling Technology, 51QIAGEN
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Pathways related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 17)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.5TPM1, ACTC1, PLN, TTN, MYH7, MYBPC3
2
Hide members
11.4MYL3, MYBPC2, MYL2, TNNC1, TNNI3, TNNT2
311.2TNNT2, TPM1, ACTC1, MYH7, MYH6, MYL3
410.9TNNT2, TNNI3, MYL2, MYH6, ACTC1
5
Cell adhesion Integrin-mediated cell adhesion and migration
Hide members
10.9MYL2, MYL3, MYH6, MYH7, ACTC1
610.9TPM1, ACTC1, MYO6, TNNI3, TNNT2
7
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
8
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
9
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
10
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
11
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
12
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
13
Immune response CCR3 signaling in eosinophils
Hide members
10.8MYH7, MYH6, MYL3, MYL2
1410.8MYH7, MYH6, MYL3, MYL2
15
Hide members
10.8PLN, TNNC1, TNNI3, TNNT2
1610.7MYH7, MYH6, MYL2
1710.6MYH7, MYL2

Compounds for genes affiliated with Hypertrophic Cardiomyopathy

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44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium44 49 11 2414.9TPM1, CALR3, TNNT2, TNNI3, TNNC1, MYL2
2creatinine4411.3TNNT2, TNNI3, MYOZ2, MYL3, MYH7, TTN
3bts5911.0MYH6, MYL3, MYL2, MYH7
4atp44 2812.0SLC25A4, TTN, MYH7, MYBPC3, MYO6, MYH6
5(r)-(+)-blebbistatin5911.0MYH7, MYH6, MYL3, MYL2
6(s)-(-)-blebbistatin5910.9MYL2, MYH7, MYH6, MYL3
7(+-)-blebbistatin5910.9MYH7, MYH6, MYL3, MYL2
8actomyosin4410.8TNNC1, MYH7, TTN, ACTC1
9n-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide44 1111.5TNNC1, TNNI3
10ryanodine44 28 5912.4MYH6, MYH7, TTN

GO Terms for genes affiliated with Hypertrophic Cardiomyopathy

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16Gene Ontology
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Cellular components related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00582911.8TNNT2, TNNI3, TNNC1, MYL2, MYBPC2, MYL3
2sarcomereGO:03001711.6TPM1, TNNT2, TNNI3, MYL2, MYOZ2, MYL3
3Z discGO:03001811.2CSRP3, MYOZ2, MYH6, MYH7, TTN, TCAP
4I bandGO:03167411.0MYL3, TTN, TCAP, ACTC1
5troponin complexGO:00586110.9TNNC1, TNNI3, TNNT2
6myosin filamentGO:03298210.9MYBPC2, MYH6, MYH7
7muscle myosin complexGO:00585910.9MYL3, MYH6, MYH7
8myosin complexGO:01645910.8MYH7, MYH6, MYL2
9stress fiberGO:00172510.8MYH6, MYH7, TPM1
10striated muscle thin filamentGO:00586510.6TTN, TNNT2
11myofibrilGO:03001610.6MYH6, MYL2
12A bandGO:03167210.5MYBPC3, MYL3
13filamentous actinGO:03194110.3TPM1, MYO6

Biological processes related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 28)
idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:03004911.9TPM1, ACTC1, TCAP, TTN, MYH7, MYBPC3
2cardiac muscle contractionGO:06004811.7MYBPC3, MYL3, MYL2, TNNC1, TNNI3, CSRP3
3ventricular cardiac muscle tissue morphogenesisGO:05501011.6TNNT2, TPM1, MYH7, MYBPC3, MYH6, MYL3
4sarcomere organizationGO:04521411.3TNNT2, MYH6, MYBPC3, TTN, TCAP, TPM1
5cardiac myofibril assemblyGO:05500311.2CSRP3, MYL2, TTN, TCAP, ACTC1
6positive regulation of ATPase activityGO:03278111.2TNNT2, MYL3, MYBPC3, TPM1
7adult heart developmentGO:00751211.1MYH6, MYH7, TTN, TCAP
8regulation of the force of heart contractionGO:00202611.1PLN, MYH6, MYL3, CSRP3
9regulation of heart contractionGO:00801611.1TPM1, PLN, MYH6, TNNT2
10detection of muscle stretchGO:03599511.1CSRP3, TTN, TCAP
11skeletal muscle thin filament assemblyGO:03024011.0TTN, TCAP, ACTC1
12cardiac muscle hypertrophyGO:00330011.0CSRP3, TTN, TCAP
13cardiac muscle fiber developmentGO:04873911.0MYH6, TTN, TCAP
14negative regulation of ATPase activityGO:03278011.0PLN, TNNI3, TNNT2
15ATP catabolic processGO:00620011.0TNNT2, MYH6, MYH7, ACTC1
16regulation of striated muscle contractionGO:00694211.0MYBPC3, MYL3, MYL2
17heart contractionGO:06004711.0TNNI3, MYL2, ACTC1
18muscle contractionGO:00693611.0TPM1, TTN, MYH7, MYH6
19cardiac muscle tissue morphogenesisGO:05500811.0ACTC1, TCAP, TTN
20cardiac muscle tissue developmentGO:04873811.0NDUFV2, CSRP3, PLN
21regulation of muscle contractionGO:00693710.9TPM1, TNNC1, TNNT2
22regulation of heart rateGO:00202710.9MYH6, MYBPC3, MYH7
23skeletal muscle myosin thick filament assemblyGO:03024110.7TCAP, TTN
24sarcomerogenesisGO:04876910.7TCAP, TTN
25regulation of ATPase activityGO:04346210.6TNNC1, MYH6
26actin filament-based movementGO:03004810.6ACTC1, MYO6
27atrial cardiac muscle tissue morphogenesisGO:05500910.5MYH6, TNNT2
28striated muscle contractionGO:00694110.3TTN, MYH6

Molecular functions related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1structural constituent of muscleGO:00830711.6TPM1, CSRP3, MYL2, MYBPC2, MYL3, MYH6
2actin bindingGO:00377911.5TNNT2, TNNI3, MYOZ2, MYBPC2, MYH6, MYO6
3protein bindingGO:00551511.4MYOZ2, MYL2, TNNC1, TNNI3, CSRP3, MYBPC2
4ATPase activityGO:01688711.1TNNT2, MYH6, MYH7, ACTC1
5calmodulin bindingGO:00551611.0MYH6, MYO6, MYH7, TTN
6telethonin bindingGO:03143311.0TTN, MYOZ2, CSRP3
7myosin heavy chain bindingGO:03203610.9MYL2, MYBPC3
8troponin T bindingGO:03101410.9TNNI3, TNNC1
9troponin C bindingGO:03017210.9TNNT2, TNNI3
10actin filament bindingGO:05101510.9TTN, MYO6, TNNC1
11actinin bindingGO:04280510.9CSRP3, TTN
12troponin I bindingGO:03101310.8TNNT2, TNNC1
13actin-dependent ATPase activityGO:03089810.8MYH6, MYH7
14calcium ion bindingGO:00550910.8CALR3, TNNC1, MYL2, MYL3, TTN
15titin bindingGO:03143210.8TCAP, MYBPC3
16actin monomer bindingGO:00378510.7MYL3, MYL2
17myosin bindingGO:01702210.6ACTC1, MYBPC3
18microfilament motor activityGO:00014610.3MYH7, MYH6

Products for genes affiliated with Hypertrophic Cardiomyopathy

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Sources for Hypertrophic Cardiomyopathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet