MCID: HYP061
MIFTS: 61

Hypertrophic Cardiomyopathy malady

Cardiovascular diseases category

Summaries for Hypertrophic Cardiomyopathy

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63Wikipedia, 46OMIM, 19GeneReviews, 32MalaCards
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Wikipedia:63 Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in... more...

MalaCards: Hypertrophic Cardiomyopathy, also known as hypertrophic obstructive cardiomyopathy, is related to familial hypertrophic cardiomyopathy and dilated cardiomyopathy. An important gene associated with Hypertrophic Cardiomyopathy is MYH7 (myosin, heavy chain 7, cardiac muscle, beta), and among its related pathways are Hypertrophic cardiomyopathy (HCM) and Striated Muscle Contraction. The compounds calcium and creatinine have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and brain, and related mouse phenotypes are muscle and mortality/aging.

Description from OMIM:46 192600

GeneReviews summary for hyper-card

Aliases & Classifications for Hypertrophic Cardiomyopathy

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8Disease Ontology, 19GeneReviews, 10DISEASES, 60UMLS, 44Novoseek, 56SNOMED-CT, 34MeSH, 39NCIt, 46OMIM, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

hypertrophic cardiomyopathy 8 19 10 60
hypertrophic obstructive cardiomyopathy 8
cardiomyopathy hypertrophic obstructive 44
primary hypertrophic cardiomyopathy 8
cardiomyopathy, hypertrophic 8
hyper. obst. cardiomyopathy 8
hypertrophic myocardiopathy 8


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Disease Ontology8 DOID:11984
MeSH34 D002312
NCIt39 C34449
OMIM46 192600
ICD9CM27 425.1
ICD1025 I42.1

Related Diseases for Hypertrophic Cardiomyopathy

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17GeneCards, 18GeneDecks
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Diseases in the Familial Hypertrophic Cardiomyopathy family:

hypertrophic cardiomyopathy Cav3-Related Hypertrophic Cardiomyopathy
Myh7-Related Familial Hypertrophic Cardiomyopathy Tnnt2-Related Familial Hypertrophic Cardiomyopathy
Tpm1-Related Familial Hypertrophic Cardiomyopathy Mybpc3-Related Familial Hypertrophic Cardiomyopathy
Tnni3-Related Familial Hypertrophic Cardiomyopathy Myl3-Related Familial Hypertrophic Cardiomyopathy
Myl2-Related Familial Hypertrophic Cardiomyopathy Ttn-Related Familial Hypertrophic Cardiomyopathy
Actc1-Related Familial Hypertrophic Cardiomyopathy Myh6-Related Familial Hypertrophic Cardiomyopathy
Tcap-Related Familial Hypertrophic Cardiomyopathy Csrp3-Related Familial Hypertrophic Cardiomyopathy
Tnnc1-Related Familial Hypertrophic Cardiomyopathy Actn2-Related Familial Hypertrophic Cardiomyopathy
Myoz2-Related Familial Hypertrophic Cardiomyopathy Nexn-Related Familial Hypertrophic Cardiomyopathy
Pln-Related Familial Hypertrophic Cardiomyopathy Cardiomyopathy, Familial Hypertrophic, 20
Cardiomyopathy, Familial Hypertrophic, 2 Cardiomyopathy, Familial Hypertrophic, 9
Cardiomyopathy, Familial Hypertrophic, 13 Cardiomyopathy, Familial Hypertrophic, 8
Cardiomyopathy, Familial Hypertrophic, 16 Cardiomyopathy, Familial Hypertrophic, 18
Cardiomyopathy, Familial Hypertrophic, 21 Cardiomyopathy, Familial Hypertrophic 6
Cardiomyopathy, Familial Hypertrophic, 15 Cardiomyopathy, Familial Hypertrophic, 12
Cardiomyopathy, Familial Hypertrophic, 4 Cardiomyopathy, Familial Hypertrophic, 10
Cardiomyopathy, Familial Hypertrophic, 14 Cardiomyopathy, Familial Hypertrophic, 1
Cardiomyopathy, Familial Hypertrophic, 11 Cardiomyopathy, Familial Hypertrophic, 3
Cardiomyopathy, Familial Hypertrophic, 19 Cardiomyopathy, Familial Hypertrophic, 7
Cardiomyopathy, Familial Hypertrophic 17 Hypertrophic Cardiomyopathy Due to Intensive Athletic Training

Diseases related to Hypertrophic Cardiomyopathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 295)
idRelated DiseaseScoreTop Affiliating Genes
1familial hypertrophic cardiomyopathy31.9CALR3, CSRP3, TNNT2, TPM1, ACTC1, TNNI3
2dilated cardiomyopathy31.0MYBPC2, MYH6, MYBPC3, MYH7, TTN, PLN
3noonan syndrome30.9TCAP, SLC25A4, PLN, TTN, MYH7, MYBPC3
4myopathy30.8MYOZ2, TNNT2, TNNI3, MYH6, MYH7, TTN
5myocardial infarction30.7MYL3, TNNI3, TNNT2
6nemaline myopathy30.6ACTC1
7myocarditis30.5MYH6, TNNT2, TNNI3
8acute myocardial infarction30.3MYH7, TNNT2, TNNI3, MYL3
9congestive heart failure30.3TNNI3, TNNT2
10ischemia30.3TTN, MYH7, TNNT2
11myotonic dystrophy30.2MYH7
12diastolic heart failure30.2TTN
13hypertension10.7
14alcoholic cardiomyopathy10.6
15hypertensive heart disease10.6
16leopard syndrome10.4
17fabry disease10.4
18wolff-parkinson-white syndrome10.4
19long qt syndrome10.4
20costello syndrome10.3
21glycogen storage disease10.3
22fatal infantile hypertrophic cardiomyopathy due to mitochondrial complex i deficiency10.3
23angiodysplasia10.3
24friedreich ataxia10.3
25danon disease10.3
26ventricular septal defect10.3
27deafness, autosomal dominant 2210.3
28cardiac tamponade10.2
29mitral valve prolapse10.2
30cardiac sarcoidosis10.2
31tetralogy of fallot10.2
32myocardial stunning10.2
33septal myocardial infarction10.2
34acute myocarditis10.2
35congenital disorder of glycosylation10.2
36endocarditis10.2
37lactic acidosis10.2
38obesity10.2
39sarcoidosis10.2
40combined oxidative phosphorylation deficiency 1010.2
41hypertrophic cardiomyopathy, midventricular, digenic10.2
42mucopolysaccharidosis ih10.2
43maternally-inherited mitochondrial hypertrophic cardiomyopathy10.2
44hypertrophic cardiomyopathy due to intensive athletic training10.2
45hypertrophic cardiomyopathy and renal tubular disease due to mitochondrial dna mutation10.2
46mixed connective tissue disease10.1
47systolic heart failure10.1
48connective tissue disease10.1
49hemolytic anemia10.1
50pheochromocytoma10.1

Graphical network of the top 20 diseases related to Hypertrophic Cardiomyopathy:



Diseases related to hypertrophic cardiomyopathy

Clinical Features for Hypertrophic Cardiomyopathy

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46OMIM
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Clinical features from OMIM:

192600

Drugs & Therapeutics for Hypertrophic Cardiomyopathy

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Hypertrophic Cardiomyopathy

Drug clinical trials:

Search ClinicalTrials for Hypertrophic Cardiomyopathy

Search NIH Clinical Center for Hypertrophic Cardiomyopathy

Search CenterWatch for Hypertrophic Cardiomyopathy

Genetic Tests for Hypertrophic Cardiomyopathy

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Anatomical Context for Hypertrophic Cardiomyopathy

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32MalaCards
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MalaCards organs/tissues related to Hypertrophic Cardiomyopathy:

32
Heart, Testes, Brain, Endothelial, Cardiac myocytes, Skeletal muscle, Liver, Kidney, Skin, Monocytes, Smooth muscle

Animal Models for Hypertrophic Cardiomyopathy or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Hypertrophic Cardiomyopathy:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000536911.4TNNT2, CSRP3, ACTC1, TCAP, SLC25A4, PLN
2MP:001076811.4ACTC1, PLN, TTN, MYO6, MYH6, NDUFV2
3MP:000538511.4MYBPC3, MYL2, TNNT2, CSRP3, TNNI3, MYOZ2
4MP:000537611.1MYH6, MYOZ2, MYL2, TNNT2, CSRP3, MYO6

Publications for Hypertrophic Cardiomyopathy

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50PubMed
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Articles related to Hypertrophic Cardiomyopathy:

(show top 50)    (show all 1423)
idTitleAuthorsYear
1
Early myoclonic epilepsy, hypertrophic cardiomyopathy and subsequently a nephrotic syndrome in a patient with CoQ10 deficiency caused by mutations in para-hydroxybenzoate-polyprenyl transferase (COQ2). (23816342)
2013
2
Clostridial myonecrosis, haemolytic anaemia, hepatopathy, osteitis and transient hypertrophic cardiomyopathy after intramuscular injection in a Thoroughbred gelding. (23614516)
2013
3
Increased amount of interstitial fibrosis predicts ventricular arrhythmias, and is associated with reduced myocardial septal function in patients with obstructive hypertrophic cardiomyopathy. (23426552)
2013
4
MYBPC3 in hypertrophic cardiomyopathy: from mutation identification to RNA-based correction. (24337823)
2013
5
Evaluation of the autonomic function in patients with hypertrophic cardiomyopathy with and without syncope. (23503828)
2013
6
Identification and confirmation of haptoglobin as a potential serum biomarker in hypertrophic cardiomyopathy using proteomic approaches. (23701180)
2013
7
T1 mapping for detection of left ventricular myocardial fibrosis in hypertrophic cardiomyopathy: a preliminary study. (23333530)
2013
8
Mobile subpulmonary membrane in a patient with hypertrophic cardiomyopathy and right ventricular mid-cavitary obstruction. (23798580)
2013
9
Preserved cross-bridge kinetics in human hypertrophic cardiomyopathy patients with MYBPC3 mutations. (24186209)
2013
10
Long-term outcomes in hypertrophic cardiomyopathy caused by mutations in the cardiac troponin T gene. (22144547)
2012
11
Heart Failure Due to Severe Hypertrophic Cardiomyopathy Reversed by Low Calorie, High Protein Dietary Adjustments in a Glycogen Storage Disease Type IIIa Patient. (23430911)
2012
12
I^ Blockers for prevention of exercise-induced left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy. (22633205)
2012
13
Plasma pro-B-type natriuretic peptide testing as a screening method for hypertrophic cardiomyopathy. (22748490)
2012
14
Insights and challenges in hypertrophic cardiomyopathy, 2012. (23008086)
2012
15
Long-range effects of familial hypertrophic cardiomyopathy mutations E180G and D175N on the properties of tropomyosin. (22794249)
2012
16
Expression of hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN4) is increased in hypertrophic cardiomyopathy. (20207172)
2011
17
A novel m.3395A>G missense mutation in the mitochondrial ND1 gene associated with the new tRNA(Ile) m.4316A>G mutation in a patient with hypertrophic cardiomyopathy and profound hearing loss. (21144833)
2011
18
Mutations in the mitochondrial complex I assembly factor NDUFAF1 cause fatal infantile hypertrophic cardiomyopathy. (21931170)
2011
19
Reversible cardiogenic shock in hypertrophic cardiomyopathy after alcohol septal ablation. (21074128)
2010
20
Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopathy: AT1R as a potential modifier. (20594303)
2010
21
The relationship between angiotensin converting enzyme gene I/D polymorphism and QT dispersion in patients with hypertrophic cardiomyopathy. (20478904)
2010
22
Hypertrophic cardiomyopathy due to beta-myosin heavy chain mutation with extreme phenotypic variability within a family. (18374998)
2009
23
Hypertrophic cardiomyopathy. A study of the troponin-T gene in 127 Spanish families. (20038417)
2009
24
Whole-heart magnetic resonance imaging of isolated subpulmonary stenosis associated with hypertrophic cardiomyopathy. (19812812)
2009
25
Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction. (19273718)
2009
26
Syncope from dynamic left ventricular outflow tract obstruction simulating hypertrophic cardiomyopathy in a patient with primary AL-type amyloid heart disease. (19436787)
2009
27
Dilated phase of hypertrophic cardiomyopathy caused by Fabry disease with atrial flutter and ventricular tachycardia. (19632534)
2009
28
A novel hot-spot mutation S236G in the cardiac myosin binding protein C gene in Chinese patient with hypertrophic cardiomyopathy]. (20193176)
2009
29
A case of mixed connective tissue disease complicated with hypertrophic obstructive cardiomyopathy. (18493766)
2008
30
Dietary copper supplementation reverses hypertrophic cardiomyopathy induced by chronic pressure overload in mice. (17339407)
2007
31
Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy. (16754630)
2006
32
Morphologic characteristics of hypertrophic cardiomyopathy of the elderly with cardiac myosin-binding protein C gene mutations. (16799241)
2006
33
E22K mutation of RLC that causes familial hypertrophic cardiomyopathy in heterozygous mouse myocardium: effect on cross-bridge kinetics. (16751284)
2006
34
Amyloid heart disease mimicking hypertrophic cardiomyopathy. (16115295)
2005
35
Circulating levels of heart-type fatty acid-binding protein and its relation to thallium-201 perfusion defects in patients with hypertrophic cardiomyopathy. (15904639)
2005
36
Valsartan decreases type I collagen synthesis in patients with hypertrophic cardiomyopathy. (16195625)
2005
37
Reversion of hypertrophic cardiomyopathy in a patient with deficiency of the mitochondrial copper binding protein Sco2: is there a potential effect of copper? (14970747)
2004
38
Familial hypertrophic cardiomyopathy complicated by complete atrioventricular block. (15030138)
2004
39
Increased circulating matrix metalloproteinase-2 in patients with hypertrophic cardiomyopathy with systolic dysfunction. (15056834)
2004
40
Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. (15541368)
2004
41
Coronary endothelium-dependent and independent vasomotor responses in patients with hypertrophic cardiomyopathy. (11999662)
2002
42
Molecular genetics and pathogenesis of hypertrophic cardiomyopathy. (11740432)
2001
43
Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy. (10764406)
2000
44
A mouse model of myosin binding protein C human familial hypertrophic cardiomyopathy. (9769321)
1998
45
Three hypotonic neonates with hypertrophic cardiomyopathy: Pompe's disease]. (9752027)
1998
46
Missing pieces: myosin binding protein C truncations in familial hypertrophic cardiomyopathy. (9048665)
1997
47
Prognostic significance of beta-myosin heavy chain mutations is reflective of their hypertrophic expressivity in patients with hypertrophic cardiomyopathy. (9154300)
1997
48
Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice. (9045856)
1997
49
Myocardial stunning in hypertrophic cardiomyopathy with normal coronary arteries. (8891807)
1996
50
The COX8 gene is not the disease gene of the CMH4 locus in familial hypertrophic cardiomyopathy. (7473670)
1995

Genetic Variations for Hypertrophic Cardiomyopathy

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Expression for genes affiliated with Hypertrophic Cardiomyopathy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypertrophic Cardiomyopathy

Search GEO for disease gene expression data for Hypertrophic Cardiomyopathy.

Pathways for genes affiliated with Hypertrophic Cardiomyopathy

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29KEGG, 37NCBI BioSystems Database, 53Reactome, 12EMD Millipore, 4Cell Signaling Technology, 51QIAGEN
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Pathways related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 17)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.5TPM1, ACTC1, PLN, TTN, MYH7, MYBPC3
2
Hide members
11.4MYL3, MYBPC2, MYL2, TNNC1, TNNI3, TNNT2
311.2TNNT2, TPM1, ACTC1, MYH7, MYH6, MYL3
410.9TNNT2, TNNI3, MYL2, MYH6, ACTC1
5
Cell adhesion Integrin-mediated cell adhesion and migration
Hide members
10.9MYL2, MYL3, MYH6, MYH7, ACTC1
610.9TPM1, ACTC1, MYO6, TNNI3, TNNT2
7
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
8
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
9
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
10
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
11
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
12
Hide members
10.9MYL2, MYL3, MYH6, MYO6, MYH7
13
Immune response CCR3 signaling in eosinophils
Hide members
10.8MYH7, MYH6, MYL3, MYL2
1410.8MYH7, MYH6, MYL3, MYL2
15
Hide members
10.8PLN, TNNC1, TNNI3, TNNT2
1610.7MYH7, MYH6, MYL2
1710.6MYH7, MYL2

Compounds for genes affiliated with Hypertrophic Cardiomyopathy

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44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1calcium44 49 11 2414.9TPM1, CALR3, TNNT2, TNNI3, TNNC1, MYL2
2creatinine4411.3TNNT2, TNNI3, MYOZ2, MYL3, MYH7, TTN
3bts5911.0MYH6, MYL3, MYL2, MYH7
4atp44 2812.0SLC25A4, TTN, MYH7, MYBPC3, MYO6, MYH6
5(r)-(+)-blebbistatin5911.0MYH7, MYH6, MYL3, MYL2
6(s)-(-)-blebbistatin5910.9MYL2, MYH7, MYH6, MYL3
7(+-)-blebbistatin5910.9MYH7, MYH6, MYL3, MYL2
8actomyosin4410.8TNNC1, MYH7, TTN, ACTC1
9n-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide44 1111.5TNNC1, TNNI3
10ryanodine44 28 5912.4MYH6, MYH7, TTN

GO Terms for genes affiliated with Hypertrophic Cardiomyopathy

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16Gene Ontology
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Cellular components related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00582911.8TNNT2, TNNI3, TNNC1, MYL2, MYBPC2, MYL3
2sarcomereGO:03001711.6TPM1, TNNT2, TNNI3, MYL2, MYOZ2, MYL3
3Z discGO:03001811.2CSRP3, MYOZ2, MYH6, MYH7, TTN, TCAP
4I bandGO:03167411.0MYL3, TTN, TCAP, ACTC1
5troponin complexGO:00586110.9TNNC1, TNNI3, TNNT2
6myosin filamentGO:03298210.9MYBPC2, MYH6, MYH7
7muscle myosin complexGO:00585910.9MYL3, MYH6, MYH7
8myosin complexGO:01645910.8MYH7, MYH6, MYL2
9stress fiberGO:00172510.8MYH6, MYH7, TPM1
10striated muscle thin filamentGO:00586510.6TTN, TNNT2
11myofibrilGO:03001610.6MYH6, MYL2
12A bandGO:03167210.5MYBPC3, MYL3
13filamentous actinGO:03194110.3TPM1, MYO6

Biological processes related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 28)
idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:03004911.9TPM1, ACTC1, TCAP, TTN, MYH7, MYBPC3
2cardiac muscle contractionGO:06004811.7MYBPC3, MYL3, MYL2, TNNC1, TNNI3, CSRP3
3ventricular cardiac muscle tissue morphogenesisGO:05501011.6TNNT2, TPM1, MYH7, MYBPC3, MYH6, MYL3
4sarcomere organizationGO:04521411.3TNNT2, MYH6, MYBPC3, TTN, TCAP, TPM1
5cardiac myofibril assemblyGO:05500311.2CSRP3, MYL2, TTN, TCAP, ACTC1
6positive regulation of ATPase activityGO:03278111.2TNNT2, MYL3, MYBPC3, TPM1
7adult heart developmentGO:00751211.1MYH6, MYH7, TTN, TCAP
8regulation of the force of heart contractionGO:00202611.1PLN, MYH6, MYL3, CSRP3
9regulation of heart contractionGO:00801611.1TPM1, PLN, MYH6, TNNT2
10detection of muscle stretchGO:03599511.1CSRP3, TTN, TCAP
11skeletal muscle thin filament assemblyGO:03024011.0TTN, TCAP, ACTC1
12cardiac muscle hypertrophyGO:00330011.0CSRP3, TTN, TCAP
13cardiac muscle fiber developmentGO:04873911.0MYH6, TTN, TCAP
14negative regulation of ATPase activityGO:03278011.0PLN, TNNI3, TNNT2
15ATP catabolic processGO:00620011.0TNNT2, MYH6, MYH7, ACTC1
16regulation of striated muscle contractionGO:00694211.0MYBPC3, MYL3, MYL2
17heart contractionGO:06004711.0TNNI3, MYL2, ACTC1
18muscle contractionGO:00693611.0TPM1, TTN, MYH7, MYH6
19cardiac muscle tissue morphogenesisGO:05500811.0ACTC1, TCAP, TTN
20cardiac muscle tissue developmentGO:04873811.0NDUFV2, CSRP3, PLN
21regulation of muscle contractionGO:00693710.9TPM1, TNNC1, TNNT2
22regulation of heart rateGO:00202710.9MYH6, MYBPC3, MYH7
23skeletal muscle myosin thick filament assemblyGO:03024110.7TCAP, TTN
24sarcomerogenesisGO:04876910.7TCAP, TTN
25regulation of ATPase activityGO:04346210.6TNNC1, MYH6
26actin filament-based movementGO:03004810.6ACTC1, MYO6
27atrial cardiac muscle tissue morphogenesisGO:05500910.5MYH6, TNNT2
28striated muscle contractionGO:00694110.3TTN, MYH6

Molecular functions related to Hypertrophic Cardiomyopathy according to GeneCards/GeneDecks:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1structural constituent of muscleGO:00830711.6TPM1, CSRP3, MYL2, MYBPC2, MYL3, MYH6
2actin bindingGO:00377911.5TNNT2, TNNI3, MYOZ2, MYBPC2, MYH6, MYO6
3protein bindingGO:00551511.4MYOZ2, MYL2, TNNC1, TNNI3, CSRP3, MYBPC2
4ATPase activityGO:01688711.1TNNT2, MYH6, MYH7, ACTC1
5calmodulin bindingGO:00551611.0MYH6, MYO6, MYH7, TTN
6telethonin bindingGO:03143311.0TTN, MYOZ2, CSRP3
7myosin heavy chain bindingGO:03203610.9MYL2, MYBPC3
8troponin T bindingGO:03101410.9TNNI3, TNNC1
9troponin C bindingGO:03017210.9TNNT2, TNNI3
10actin filament bindingGO:05101510.9TTN, MYO6, TNNC1
11actinin bindingGO:04280510.9CSRP3, TTN
12troponin I bindingGO:03101310.8TNNT2, TNNC1
13actin-dependent ATPase activityGO:03089810.8MYH6, MYH7
14calcium ion bindingGO:00550910.8CALR3, TNNC1, MYL2, MYL3, TTN
15titin bindingGO:03143210.8TCAP, MYBPC3
16actin monomer bindingGO:00378510.7MYL3, MYL2
17myosin bindingGO:01702210.6ACTC1, MYBPC3
18microfilament motor activityGO:00014610.3MYH7, MYH6

Products for genes affiliated with Hypertrophic Cardiomyopathy

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Sources for Hypertrophic Cardiomyopathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet