MCID: HYP058
MIFTS: 36

Hypervitaminosis a malady

Category: Metabolic diseases

Aliases & Classifications for Hypervitaminosis a

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Aliases & Descriptions for Hypervitaminosis a:

Name: Hypervitaminosis a 10 47 12 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:9972
ICD1027 E67.0
SNOMED-CT59 64559002
ICD9CM29 278.2
MeSH36 D006986
UMLS65 C0020579

Summaries for Hypervitaminosis a

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Wikipedia:68 Hypervitaminosis A refers to the toxic effects of ingesting too much preformed vitamin A. Symptoms arise... more...

MalaCards based summary: Hypervitaminosis a is related to spastic ataxia 2 and familial retinoblastoma. An important gene associated with Hypervitaminosis a is RBP4 (Retinol Binding Protein 4), and among its related pathways are Diseases associated with visual transduction and the visual cycle I (vertebrates). Affiliated tissues include bone, liver and breast, and related mouse phenotypes are vision/eye and muscle.

Related Diseases for Hypervitaminosis a

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Graphical network of the top 20 diseases related to Hypervitaminosis a:



Diseases related to hypervitaminosis a

Symptoms for Hypervitaminosis a

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Drugs & Therapeutics for Hypervitaminosis a

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Hypervitaminosis a


Cochrane evidence based reviews: hypervitaminosis a

Genetic Tests for Hypervitaminosis a

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Anatomical Context for Hypervitaminosis a

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MalaCards organs/tissues related to Hypervitaminosis a:

33
Bone, Liver, Breast, Prostate, Heart, Endothelial, Lung

Animal Models for Hypervitaminosis a or affiliated genes

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MGI Mouse Phenotypes related to Hypervitaminosis a:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.3CDKN1A, CDKN1B, RBP4, TTR, TWIST2
2MP:00053698.1CDKN1A, CDKN1B, MGP, RBP4, TWIST2

Publications for Hypervitaminosis a

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Articles related to Hypervitaminosis a:

(show top 50)    (show all 350)
idTitleAuthorsYear
1
Hypervitaminosis a causing hypercalcemia in cystic fibrosis. Case report and focused review. (25188737)
2014
2
Microarray profiling of diaphyseal bone of rats suffering from hypervitaminosis A. (22215263)
2012
3
Case of hypercalcemia secondary to hypervitaminosis a in a 6-year-old boy with autism. (22937283)
2011
4
Acute hypervitaminosis A in a young lady. (20395929)
2010
5
Subclinical hypervitaminosis A in rat: measurements of bone mineral density (BMD) do not reveal adverse skeletal changes. (16289060)
2006
6
Back-scattered electron imaging of a non-vertebral case of hypervitaminosis A in a cat. (11716591)
2000
7
Assessment of risk factors for carotenodermia and cutaneous signs of hypervitaminosis A in college-aged populations. (1764358)
1991
8
Protein-energy malnutrition increases teratogenicity of hypervitaminosis A in rats. (3147800)
1988
9
Hepatic and dermatologic manifestations of chronic hypervitaminosis A in adults. Report of two cases. (2937294)
1986
10
Hypervitaminosis A in a child from megadosing. (3988928)
1985
11
Ingestion of shark liver associated with pseudotumor cerebri due to acute hypervitaminosis A. (6707663)
1984
12
Discordant hepatic uptake between Tc-99m sulfur colloid and Tc-99m DISIDA in hypervitaminosis A. (6539369)
1984
13
Clinical manifestations of hypervitaminosis A in human gingiva. A case report. (6592319)
1984
14
Oxygen consumption and survival prediction in neonatal rats exposed to prenatal hypervitaminosis A. (6417812)
1983
15
Protein-calorie deficiency and vitamin indiscretion in an atopic child who developed hypervitaminosis A. (6799241)
1982
16
Morphometric study of malformations induced by hypervitaminosis A on rat fetus Meckel cartilage, maxillary bone and mandible. (6762114)
1982
17
Malformations of the eye resulting from maternal hypervitaminosis A during gestation in the rat. (6800208)
1981
18
Overnutrition and hypervitaminosis A in the tree shrew (Lyongale tana). (96447)
1978
19
Morphometric study of the reversibility of testicle alterations in rats submitted to hypervitaminosis A. (738845)
1978
20
Early effects of hypervitaminosis A on gluconeogenic activity and amino acid metabolizing enzymes of rat liver. (20486)
1977
21
Morphologic alterations associated with decreased cerebrospinal fluid pressure in chronic bovine hypervitaminosis A. (1111381)
1975
22
Ultrastructural changes in livers of two patients with hypervitaminosis A. (4416771)
1974
23
Effect of hypervitaminosis A on immunocompetence in rats. (4549758)
1974
24
A light and electron microscopic study of the lymphomyeloid complex in hypervitaminosis A. (5075296)
1972
25
Lack of hypertrophy of the adrenal in exencephalic fetal rats subjected to hypervitaminosis A and then to maternal adrenalectomy. (4324682)
1971
26
Hypervitaminosis A dysmelia in rats. (4332598)
1971
27
Rates of formation and absorption of cerebrospinal fluid in mild chronic bovine hypervitaminosis A. (5479487)
1970
28
Hypothalamic-hypophysial adrenal and thyroid systems: observations in fetal rats subjected to hypothalamic destruction, brain compression and hypervitaminosis A. (5436115)
1970
29
Excessive dietary vitamin E: its alleviation of hypervitaminosis A and lack of toxicity. (5485475)
1970
30
Hepatic injury in chronic hypervitaminosis A. (5410560)
1970
31
Effects of ovariectomy and hypervitaminosis A on lysosomes of the rat conceptus. (4312014)
1969
32
Effect of hypervitaminosis A on intestinal lipids of rats. (6048389)
1967
33
Dental malformations in rat embryos with exencephaly induced by hypervitaminosis A. (5236137)
1967
34
Bone strength and calcium retention of rats in hypervitaminosis-A. (5178796)
1966
35
MALFORMATIONS OF THE MOUSE FETUS CAUSED BY HYPERVITAMINOSIS-A OF THE MOTHER DURING PREGNANCY. (14280198)
1965
36
ALTERATIONS IN THE LIPIDS OF BONE CAUSED BY HYPERVITAMINOSIS A AND D. (14343141)
1965
37
Carbohydrate metabolism in hypervitaminosis A. (14436609)
1959
38
Late effects of hypervitaminosis A in the rat; disturbance and retardation in the normal growth of offspring. (13570808)
1958
39
Hypervitaminosis A; toxic reaction. (13508636)
1958
40
Hypervitaminosis A. (13425777)
1957
41
Metabolism of calcium, phosphorus and nitrogen in hypervitaminosis A in young rats. (13328832)
1956
42
Chronic hypervitaminosis A; report of a probable case in a man. (13265422)
1955
43
The biochemistry and pathology of hypervitaminosis A. (14374254)
1954
44
The activity of ascorbic acid in hypervitaminosis-A in the guinea-pig. (13128868)
1953
45
Hypervitaminosis; a study of an unusual case. (14934528)
1952
46
Hypervitaminosis A; a case report. (14890815)
1952
47
Effect of hypervitaminosis A on hepatic ascorbic acid in the rat. (14924655)
1952
48
Hypervitaminosis A with infantile cortical hyperostosis. (14850258)
1951
49
Hypervitaminosis A; report of a case. (14774092)
1950
50
Hypervitaminosis A; a case report. (18872296)
1948

Variations for Hypervitaminosis a

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Expression for genes affiliated with Hypervitaminosis a

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Search GEO for disease gene expression data for Hypervitaminosis a.

Pathways for genes affiliated with Hypervitaminosis a

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GO Terms for genes affiliated with Hypervitaminosis a

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Biological processes related to Hypervitaminosis a according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1mitotic cell cycle arrestGO:007185010.2CDKN1A, CDKN1B
2negative regulation of cyclin-dependent protein serine/threonine kinase activityGO:004573610.0CDKN1A, CDKN1B
3phototransduction, visible lightGO:00076039.9RBP4, TTR
4negative regulation of phosphorylationGO:00423269.9CDKN1A, CDKN1B
5G1/S transition of mitotic cell cycleGO:00000829.8CDKN1A, CDKN1B
6regulation of cyclin-dependent protein serine/threonine kinase activityGO:00000799.7CDKN1A, CDKN1B
7negative regulation of cell growthGO:00303089.7CDKN1A, CDKN1B
8positive regulation of cell deathGO:00109429.6CDKN1A, CDKN1B
9negative regulation of transcription, DNA-templatedGO:00458928.4CDKN1B, SET, TWIST2

Sources for Hypervitaminosis a

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet