MCID: HYP058
MIFTS: 37

Hypervitaminosis a malady

Category: Metabolic diseases

Aliases & Classifications for Hypervitaminosis a

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Aliases & Descriptions for Hypervitaminosis a:

Name: Hypervitaminosis a 10 47 12 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:9972
ICD1027 E67.0
SNOMED-CT59 64559002
ICD9CM29 278.2
MeSH36 D006986
UMLS65 C0020579

Summaries for Hypervitaminosis a

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Wikipedia:68 Hypervitaminosis A refers to the toxic effects of ingesting too much preformed vitamin A. Symptoms arise... more...

MalaCards based summary: Hypervitaminosis a is related to cervicitis and pancreatitis. An important gene associated with Hypervitaminosis a is RBP4 (Retinol Binding Protein 4), and among its related pathways are Diseases associated with visual transduction and the visual cycle I (vertebrates). Affiliated tissues include bone, breast and brain, and related mouse phenotypes are vision/eye and muscle.

Related Diseases for Hypervitaminosis a

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Graphical network of the top 20 diseases related to Hypervitaminosis a:



Diseases related to hypervitaminosis a

Symptoms for Hypervitaminosis a

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Drugs & Therapeutics for Hypervitaminosis a

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Hypervitaminosis a


Cochrane evidence based reviews: hypervitaminosis a

Genetic Tests for Hypervitaminosis a

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Anatomical Context for Hypervitaminosis a

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MalaCards organs/tissues related to Hypervitaminosis a:

33
Bone, Breast, Brain, Lung, Endothelial, Liver, Kidney

Animal Models for Hypervitaminosis a or affiliated genes

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MGI Mouse Phenotypes related to Hypervitaminosis a:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.3CDKN1A, CDKN1B, RBP4, TTR, TWIST2
2MP:00053698.1CDKN1A, CDKN1B, MGP, RBP4, TWIST2

Publications for Hypervitaminosis a

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Articles related to Hypervitaminosis a:

(show top 50)    (show all 350)
idTitleAuthorsYear
1
Functional characterization of TRAP1-like protein involved in modulating fibrotic processes mediated by TGF-I^/Smad signaling in hypertrophic scar fibroblasts. (25655281)
2015
2
Extending the phenotypic spectrum of RBFOX1 deletions: Sporadic focal epilepsy. (26174448)
2015
3
Pathogenic EFHC1 mutations are tolerated in healthy individuals dependent on reported ancestry. (25489633)
2015
4
Fractional flow reserve or optical coherence tomography guidance to revascularize intermediate coronary stenosis using angioplasty (FORZA) trial: study protocol for a randomized controlled trial. (24758510)
2014
5
Perceptions of coronary heart disease: the development and psychometric testing of a measurement scale. (23731251)
2014
6
Clinical Trials in Hepatocellular Carcinoma: An Update. (24400222)
2013
7
Comparison of bipolar versus monopolar extraoperative electrical cortical stimulation mapping in patients with focal epilepsy. (24135067)
2013
8
Determining and surveying the role of carnitine and folic acid to decrease fatigue in I^-thalassemia minor subjects. (23458634)
2013
9
Genetic evidence that vascular dementia is related to Alzheimer's disease: genetic association between tau polymorphism and vascular dementia in the Chinese population. (21044986)
2011
10
Hepatic macronodular tuberculoma mimics liver metastasis in a patient with locoregional advanced tongue cancer. (21606414)
2011
11
A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition. (21241693)
2011
12
A functional variant provided further evidence for the association of ARVCF with schizophrenia. (20333729)
2010
13
Paraneoplastic glomerulopathy secondary to retroperitoneal sarcoma: a case report. (20721964)
2010
14
Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components. (20080841)
2010
15
A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway. (19942856)
2010
16
Design, synthesis, and biological evaluation of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a potent, orally active, brain penetrant inhibitor of phosphodiesterase 5 (PDE5). (20196613)
2010
17
Arthritis as a hypersensitivity reaction in a case of sporotrichosis transmitted by a sick cat: clinical and serological follow up of 13 months. (19207845)
2010
18
Low expression of a few genes indicates good prognosis in estrogen receptor positive breast cancer. (19619298)
2009
19
Chronic active Epstein-Barr virus infection with mosquito allergy successfully treated with reduced-intensity unrelated allogeneic bone marrow transplantation in a boy. (18627511)
2009
20
Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness. (19242345)
2009
21
Acute elevation of triglycerides after initiation of fosamprinavir/ritonavir in an HIV-negative patient with baseline hypertriglyceridemia. (21291769)
2008
22
Concurrence of marginal zone B-cell lymphoma MALT-type and Langerhans cell histiocytosis in a thyroid gland with Hashimoto disease. (18401582)
2008
23
Head and neck paragangliomas: revision of 89 cases in 73 patients]. (17371691)
2007
24
A study of the serotonin transporter in the prefrontal cortex in late-life depression and Alzheimer's disease with and without depression. (16640648)
2006
25
Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites. (16105987)
2005
26
Primary cutaneous myxofibrosarcoma mimicking pleomorphic hyalinizing angiectatic tumor (PHAT): a potential diagnostic pitfall. (16121054)
2005
27
HCMV-encoded chemokine receptor US28 employs multiple routes for internalization. (15313171)
2004
28
Gene expression profiles in human nasal polyp tissues studied by means of DNA microarray. (15480316)
2004
29
Thienopyridine-linked thrombotic microangiopathy: association with endothelial cell apoptosis and activation of MAP kinase signalling cascades. (14687031)
2004
30
An ethyl-nitrosourea-induced point mutation in phex causes exon skipping, x-linked hypophosphatemia, and rickets. (12414538)
2002
31
Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium. (11546664)
2001
32
A Gln/Arg polymorphism at codon 349 of the hBUBR1 gene. (10083741)
1999
33
Gender identity disorder. (10361778)
1999
34
Von Willebrand disease: characteristics and response to desmopressin. Study of 103 cases]. (9881332)
1998
35
The factor V Leiden mutation increases the risk of venous thrombosis in patients with inflammatory bowel disease. (9753484)
1998
36
Myelofibrosis secondary to renal osteodystrophy. (8730443)
1996
37
Transcriptional regulation of LDL receptor-related protein by IFN-gamma and the antagonistic activity of TGF-beta(1) in the RAW 264.7 macrophage-like cell line. (8656060)
1996
38
Polyradiculopathy associated with ganciclovir-resistant cytomegalovirus in an AIDS patient: phenotypic and genotypic characterization of sequential virus isolates. (8648225)
1996
39
Myelin/oligodendrocyte glycoprotein is alternatively spliced in humans but not mice. (8915905)
1996
40
Selectable insertion and deletion mutagenesis of the human cytomegalovirus genome using the Escherichia coli guanosine phosphoribosyl transferase (gpt) gene. (7561752)
1995
41
Interleukin-1 alpha and interleukin-1 beta periapical exudates of infected root canals: correlations with the clinical findings of the involved teeth. (7996112)
1994
42
Sagittal synostosis: quantitative assessment of presenting deformity and surgical results based on CT scans. (8234497)
1993
43
The action of interleukin 6 and leukaemia inhibitory factor on liver cells. (1425008)
1992
44
Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11). (1283316)
1992
45
Characterization of a panel of monoclonal antibodies to human coagulation factor XI and detection of factor XI in Hep G2 cell conditioned medium. (2402744)
1990
46
Clotrimazole: intermittent therapy in chronic mucocutaneous candidiasis. (842517)
1977
47
Prenatal mandibulofacial dysostosis (Treacher Collins syndrome). (264276)
1977
48
Caveats of antenatal diagnosis of Tay-Sachs disease. (4685506)
1973
49
Serum vitamin B 12 level in patients with amoebic liver abscess, opisthorchiasis and hookworm infections. (5112336)
1971
50
Congenital hypoplastic anemia, report of two cases. (5514640)
1970

Variations for Hypervitaminosis a

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Expression for genes affiliated with Hypervitaminosis a

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Search GEO for disease gene expression data for Hypervitaminosis a.

Pathways for genes affiliated with Hypervitaminosis a

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GO Terms for genes affiliated with Hypervitaminosis a

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Biological processes related to Hypervitaminosis a according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1mitotic cell cycle arrestGO:007185010.2CDKN1A, CDKN1B
2negative regulation of cyclin-dependent protein serine/threonine kinase activityGO:004573610.0CDKN1A, CDKN1B
3phototransduction, visible lightGO:00076039.9RBP4, TTR
4negative regulation of phosphorylationGO:00423269.9CDKN1A, CDKN1B
5G1/S transition of mitotic cell cycleGO:00000829.8CDKN1A, CDKN1B
6regulation of cyclin-dependent protein serine/threonine kinase activityGO:00000799.7CDKN1A, CDKN1B
7negative regulation of cell growthGO:00303089.7CDKN1A, CDKN1B
8positive regulation of cell deathGO:00109429.6CDKN1A, CDKN1B
9negative regulation of transcription, DNA-templatedGO:00458928.4CDKN1B, SET, TWIST2

Sources for Hypervitaminosis a

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet