MCID: HYP121
MIFTS: 44

Hypoalphalipoproteinemia malady

Summaries for Hypoalphalipoproteinemia

Sources:
64Wikipedia, 47OMIM, 33MalaCards
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Wikipedia:64 Hypoalphalipoproteinemia is a high-density lipoprotein deficiency, inherited in an autosomal dominant... more...

MalaCards: Hypoalphalipoproteinemia, also known as hypoalphalipoproteinemias, is related to tangier disease and hypertriglyceridemia. An important gene associated with Hypoalphalipoproteinemia is APOA1 (apolipoprotein A-I), and among its related pathways are Golgi to ER Retrograde Transport and Scavenging by Class B Receptors. The compounds rosiglitazone and alpha tocopherol have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and monocytes, and related mouse phenotypes are adipose tissue and endocrine/exocrine gland.

Description from OMIM:47 604091

Aliases & Classifications for Hypoalphalipoproteinemia

Sources:
47OMIM, 45Novoseek, 61UMLS
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Aliases & Descriptions:

hypoalphalipoproteinemia 47 45
hypoalphalipoproteinemias 61


Related Diseases for Hypoalphalipoproteinemia

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Hypoalphalipoproteinemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 113)
idRelated DiseaseScoreTop Affiliating Genes
1tangier disease30.4LCAT, APOA1, ABCA1, APOA2, CETP, APOC3
2hypertriglyceridemia30.4APOA1, APOC3, APOA2, APOB, PPARA, LPA
3coronary artery disease,30.2PPARA, APOB, APOA2, APOC3, APOA1, LCAT
4hypercholesterolemia30.2LDLR, CETP, GGT1, ACE, ABCA1, LIPC
5coronary heart disease30.1APOB, APOA2, APOC3, APOA1, LCAT, PPARA
6atherosclerosis30.0LDLR, CETP, GGT1, ACE, APOB, APOC3
7hyperhomocysteinemia29.9LPA
8familial hypercholesterolemia29.9LDLR, CETP, APOB
9amyloidosis29.9APOA1, APOA2, LPA, LPL
10hyperalphalipoproteinemia29.9LIPC, ABCA1, PLTP, CETP, LDLR, APOA1
11familial hdl deficiency10.4
12lip disease10.2
13thromboembolism10.0APOA1
14lipoprotein lipase deficiency10.0LPL
15age related macular degeneration10.0LIPC
16ischemia10.0PPARA
17acute pancreatitis10.0LPL
18polyneuropathy10.0APOA2
19dermatitis10.0PPARA
20cerebral atherosclerosis10.0APOA1
21gout10.0LCAT
22arthritis10.0PPARA
23chylomicron retention disease10.0APOB
24acromegaly10.0LPA
25glomerulonephritis10.0LPA
26cystic fibrosis10.0ABCA1, LPL
27antiphospholipid syndrome10.0PLTP, LDLR
28hyperthyroidism10.0LDLR, APOA2
29asthma10.0CETP
30amyloidosis, renal10.0APOA2, APOA1
31gallbladder disease10.0GGT1
32fish-eye disease10.0LCAT, APOA1, APOA2
33osteoarthritis10.0PPARA
34psoriasis10.0PPARA, LDLR
35lipase deficiency combined10.0LIPC, LPL
36colorectal cancer10.0LDLR, LPL
37familial combined hyperlipidemia10.0APOB, APOA1
38hyperinsulinism10.0APOB, LPL
39gaucher's disease10.0GBA
40pneumonia10.0PPARA
41arcus senilis10.0APOB, APOA1, LCAT
42polycystic ovary syndrome10.0PPARA, APOA1, LIPC
43alcohol abuse10.0GGT1, LCAT
44schizophrenia10.0PPARA, LDLR
45familial hypertriglyceridemia10.0APOC3, APOB, LPL
46nephrosclerosis10.0ACE
47hepatitis10.0GGT1, LDLR
48fatty liver disease10.0PPARA, GGT1
49alagille syndrome10.0LPA, LCAT, APOA1
50pancreatitis10.0LPL, GGT1

Graphical network of the top 20 diseases related to Hypoalphalipoproteinemia:



Diseases related to hypoalphalipoproteinemia

Clinical Features for Hypoalphalipoproteinemia

Sources:
47OMIM
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Clinical features from OMIM:

604091

Drugs & Therapeutics for Hypoalphalipoproteinemia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Hypoalphalipoproteinemia

Search CenterWatch for Hypoalphalipoproteinemia

Genetic Tests for Hypoalphalipoproteinemia

Anatomical Context for Hypoalphalipoproteinemia

Sources:
33MalaCards
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MalaCards organs/tissues related to Hypoalphalipoproteinemia:

33
Kidney, Heart, Monocytes, Endothelial

Animal Models for Hypoalphalipoproteinemia or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Hypoalphalipoproteinemia

Sources:
51PubMed
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Articles related to Hypoalphalipoproteinemia:

(show top 50)    (show all 75)
idTitleAuthorsYear
1
Prevalence of classical CD14++/CD16- but not of intermediate CD14++/CD16+ monocytes in hypoalphalipoproteinemia. (23623664)
2013
2
Impact of hypoalphalipoproteinemia on quality of life in Taiwanese women with central obesity. (24322908)
2013
3
An ABCA1 truncation shows no dominant negative effect in a familial hypoalphalipoproteinemia pedigree with three ABCA1 mutations. (21575609)
2011
4
Acquired severe hypercholesterolemia and hypoalphalipoproteinemia. (21291840)
2009
5
Hypoalphalipoproteinemia in populations of Native American ancestry: an opportunity to assess the interaction of genes and the environment. (19280764)
2009
6
Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia. (19616211)
2009
7
Multiple splice defects in ABCA1 cause low HDL-C in a family with hypoalphalipoproteinemia and premature coronary disease. (19133158)
2009
8
Familial hypercholesterolemia associated with severe hypoalphalipoproteinemia in a Moroccan family. (17968143)
2007
9
Genetic variation of PLTP modulates lipoprotein profiles in hypoalphalipoproteinemia. (16388083)
2006
10
Promoter haplotype of a new ABCA1 mutant influences expression of familial hypoalphalipoproteinemia. (16225879)
2006
11
Consequences of cholesteryl ester transfer protein inhibition in patients with familial hypoalphalipoproteinemia. (16127020)
2005
12
Combined monogenic hypercholesterolemia and hypoalphalipoproteinemia caused by mutations in LDL-R and LCAT genes. (16115486)
2005
13
Severe hypoalphalipoproteinemia in mice expressing human hepatic lipase deficient in binding to heparan sulfate proteoglycan. (15292235)
2004
14
The role of the ABCA1 transporter and cholesterol efflux in familial hypoalphalipoproteinemia. (12700344)
2003
15
Early vascular damage in primary hypoalphalipoproteinemia. (12647271)
2003
16
Impaired ABCA1-dependent lipid efflux and hypoalphalipoproteinemia in human Niemann-Pick type C disease. (12813037)
2003
17
Analysis of apolipoprotein A-I, lecithin:cholesterol acyltransferase and glucocerebrosidase genes in hypoalphalipoproteinemia. (12048121)
2002
18
Corticosteroid therapy increases HDL-cholesterol concentrations in patients with active sarcoidosis and hypoalphalipoproteinemia. (11983201)
2002
19
Clinical variant of Tangier disease in Japan: mutation of the ABCA1 gene in hypoalphalipoproteinemia with corneal lipidosis. (12111371)
2002
20
Lecithin:cholesterol acyl transferase G30S: association with atherosclerosis, hypoalphalipoproteinemia and reduced in vivo enzyme activity. (11522275)
2001
21
Proteolytic degradation and impaired secretion of an apolipoprotein A-I mutant associated with dominantly inherited hypoalphalipoproteinemia. (11292828)
2001
22
Evidence of linkage of familial hypoalphalipoproteinemia to a novel locus on chromosome 11q23. (10775531)
2000
23
Gemfibrozil, nicotinic acid and combination therapy in patients with isolated hypoalphalipoproteinemia: a randomized, open-label, crossover study. (10716466)
2000
24
Hyperinsulinemic hypoalphalipoproteinemia as a new indicator for coronary heart disease. (10551691)
1999
25
Multiple dysfunctions of two apolipoprotein A-I variants, apoA-I(R160L)Oslo and apoA-I(P165R), that are associated with hypoalphalipoproteinemia in heterozygous carriers. (10064737)
1999
26
Severe atherosclerosis and hypoalphalipoproteinemia in the staggerer mouse, a mutant of the nuclear receptor RORalpha. (9851961)
1998
27
Genetic polymorphisms and mutations of the lipoprotein lipase gene in Japanese schoolchildren with hypoalphalipoproteinemia. (9730139)
1998
28
Correction of hypoalphalipoproteinemia in LDL receptor-deficient rabbits by lecithin:cholesterol acyltransferase. (9717715)
1998
29
Microsomal enzyme inducers raise plasma high-density lipoprotein cholesterol levels in healthy control subjects but not in patients with primary hypoalphalipoproteinemia. (7712672)
1995
30
Increase of gamma-glutamyltranspeptidase in patients with compensated hypoalphalipoproteinemia and type IIa dyslipidemias]. (7627821)
1995
31
Concentrations of apolipoprotein A-I-containing particles in patients with hypoalphalipoproteinemia. (8148349)
1994
32
Low levels of high-density lipoprotein cholesterol (hypoalphalipoproteinemia). An approach to management. (8323418)
1993
33
A case report: familial hypoalphalipoproteinemia. (8348223)
1993
34
Hypoalphalipoproteinemia: postprandial response of subjects with preprandial normotriglyceridemia and hypertriglyceridemia to various diets. (8474323)
1993
35
Effect of gemfibrozil and lovastatin on postprandial lipoprotein clearance in the hypoalphalipoproteinemia and hypertriglyceridemia syndrome. (8318063)
1993
36
Two patterns of LDL metabolism in normotriglyceridemic patients with hypoalphalipoproteinemia. (8466893)
1993
37
Hypoalphalipoproteinemia. (1458423)
1992
38
Analysis of familial hypoalphalipoproteinemia syndromes. (1518505)
1992
39
Postprandial lipoprotein(a) response to a single meal containing either saturated or omega-3 polyunsaturated fatty acids in subjects with hypoalphalipoproteinemia. (1461142)
1992
40
Delayed clearance of postprandial chylomicrons and their remnants in the hypoalphalipoproteinemia and mild hypertriglyceridemia syndrome. (1390590)
1992
41
Erythrocyte abnormalities in a hypoalphalipoproteinemia syndrome resembling fish eye disease. (3410011)
1988
42
Hypoalphalipoproteinemia resembling fish eye disease. (3591467)
1987
43
Insufficient evidence to invoke defects in or around the A-I gene as the cause for familial hypoalphalipoproteinemia. (3118895)
1987
44
Restriction-fragment-length polymorphisms in the A-I-C-III gene complex occurring in a family with hypoalphalipoproteinemia. (2877676)
1986
45
Familial hypoalphalipoproteinemia. (3541525)
1986
46
A major gene for primary hypoalphalipoproteinemia. (3953576)
1986
47
A family study of hypoalphalipoproteinemia. (3541526)
1986
48
Severe hypoalphalipoproteinemia induced by a combination of probucol and clofibrate. (3541510)
1986
49
A genetic study of hypoalphalipoproteinemia. (6544231)
1984
50
Primary and familial hypoalphalipoproteinemia. (6694557)
1984

Genetic Variations for Hypoalphalipoproteinemia

Expression for genes affiliated with Hypoalphalipoproteinemia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypoalphalipoproteinemia

Search GEO for disease gene expression data for Hypoalphalipoproteinemia.

Pathways for genes affiliated with Hypoalphalipoproteinemia

Sources:
54Reactome, 30KEGG, 38NCBI BioSystems Database, 12EMD Millipore, 50PharmGKB
See all sources

Pathways related to Hypoalphalipoproteinemia according to GeneCards/GeneDecks:

(show all 17)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0CETP, ABCA1
29.9APOB, APOA1
3
Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)
9.9APOA1, APOA2, ABCA1
49.7ABCA1, APOA1, APOB
59.6ABCA1, LDLR, PPARA
6
Hide members
9.6LIPC, LPL, SLC25A20
7
Hide members
9.2SLC25A20, APOA2, PPARA, ABCA1, APOA1
89.1LPA, APOB, LDLR, CETP
99.0ABCA1, LPA, APOB, APOA1, APOA2
109.0APOA1, APOC3, PPARA, LPL, PLTP, APOA2
118.9APOA2, APOB, APOC3, LDLR, APOA1, LPL
12
Hide members
8.9LDLR, LPL, APOB, APOA2, APOA1, APOC3
138.9APOB, APOA1, ABCA1, GGT1, LDLR
14
Hide members
8.4SLC25A20, LDLR, CETP, ABCA1, GGT1, GBA
15
Hide members
8.0APOA2, LCAT, APOA1, APOC3, LPA, LIPC
16
Hide members
7.8LDLR, APOC3, APOA2, APOB, LPA, LPL
17
Hide members
7.7APOB, ABCA1, PLTP, CETP, LDLR, LIPC

Compounds for genes affiliated with Hypoalphalipoproteinemia

Sources:
45Novoseek, 50PharmGKB, 29IUPHAR, 11DrugBank, 24HMDB, 60Tocris Bioscience
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Compounds related to Hypoalphalipoproteinemia according to GeneCards/GeneDecks:

(show top 50)    (show all 154)
idCompoundScoreTop Affiliating Genes
1rosiglitazone45 50 29 11 2414.2PPARA
2alpha tocopherol459.9LCAT, LPL, PLTP, LDLR
3xbai459.9LDLR, LPL, APOC3
4palmitate459.7LCAT, LDLR, CETP, PPARA
5psyllium459.6LDLR, CETP, APOB, LCAT
6fenofibric acid45 2910.4LPL, PPARA, APOB, APOC3, APOA1
7estrogen459.4LIPC, LCAT, APOC3, LPA, CETP
8dimyristoylphosphatidylcholine459.4LDLR, APOA2, APOA1, LCAT, LPA
9ciprofibrate45 2910.3LDLR, APOB, LPL, APOA1, PPARA
10p-opc459.3LCAT, APOA1, CETP, APOA2
11hind iii459.2APOC3, ABCA1, LPA, LIPC, LPL
12sele459.2APOC3, LPL, CETP, ACE, LDLR
13ezetimibe45 1110.2ABCA1, APOA1, CETP, PPARA, APOB, LDLR
14cholestyramine459.2CETP, APOC3, LPA, LDLR, APOB
15rosuvastatin45 50 29 1112.2APOB, PPARA, APOA1, CETP, LDLR, APOC3
16dextran sulfate459.1LDLR, APOA1, APOB, CETP, LPL, PLTP
17fluvastatin45 50 29 1112.0PPARA, LPL, APOA1, APOB, LDLR, CETP
18stearic acid45 11 2410.9PPARA, LPL, LIPC, ABCA1, LDLR, CETP
19taurocholate458.9LPL, APOC3, APOA1, APOB, GBA
20linoleic acid45 29 2410.9PPARA, LCAT, LPL, ABCA1, CETP, LDLR
21intralipid458.9CETP, LIPC, LPL, APOB, APOA2, APOC3
22mspi458.9APOA1, LDLR, CETP, LPA, APOB, APOA2
23carnitine458.8APOA1, APOB, PPARA, LPL, SLC25A20, ABCA1
24sterol458.7CETP, LCAT, APOB, PPARA, LIPC, ABCA1
25pioglitazone45 50 29 1111.7LPL, PPARA, GGT1, ABCA1, LIPC, APOA1
26heparin45 29 11 2411.6LPA, APOA2, LDLR, APOC3, LCAT, CETP
27niacin45 119.6CETP, ABCA1, LPL, LPA, LDLR, PPARA
28metformin45 50 1110.5GGT1, ACE, LPL, PPARA, APOB, APOA1
29pravastatin45 50 29 11 2412.4LCAT, APOA1, LDLR, CETP, ABCA1, LPA
30glucose458.3APOA1, APOC3, APOA2, LPA, LPL, GBA
31probucol45 119.3PPARA, LPL, LIPC, ABCA1, LDLR, CETP
32thyroxine45 249.2APOA1, GGT1, APOB, LPA, LPL, LIPC
33oleic acid45 29 11 2411.2APOB, PPARA, LPA, LPL, LIPC, ABCA1
34simvastatin45 50 60 29 11 2413.1LPL, LPA, PPARA, APOB, APOA1, LCAT
35triacylglycerol458.0LPL, LIPC, PLTP, CETP, LDLR, PPARA
36lovastatin45 50 60 29 1112.0APOB, APOC3, APOA1, LDLR, CETP, GGT1
37gemfibrozil45 29 1110.0PPARA, APOB, APOA2, APOC3, APOA1, LPA
38phosphatidylcholine458.0LPA, LPL, LIPC, ABCA1, PLTP, CETP
39serine457.9LDLR, APOA2, LCAT, CETP, RORA, GBA
40aspirin45 50 29 2410.8GBA, LPA, ACE, APOB, APOA1, CETP
41atorvastatin45 50 29 11 2411.8LDLR, CETP, ABCA1, LIPC, LPL, LPA
42phospholipid457.8LCAT, APOA1, APOC3, APOA2, APOB, LPL
43testosterone45 60 11 2410.7APOB, APOA1, LPL, CETP, GGT1, ABCA1
44fenofibrate45 50 119.6CETP, LDLR, PLTP, ABCA1, LIPC, APOA1
45vitamin a45 11 249.5PPARA, LPA, LPL, LIPC, GGT1, CETP
46cholesterol ester457.4LDLR, CETP, PLTP, ABCA1, PPARA, APOB
47fatty acid457.2LCAT, APOC3, APOA2, APOB, PPARA, LPA
48bezafibrate45 29 119.1LCAT, APOA1, APOC3, APOA2, APOB, PPARA
49cholesterol45 29 11 248.3LCAT, APOA1, APOC3, APOA2, APOB, PPARA
50lipid454.9GBA, PPARA, LPA, LPL, LIPC, ABCA1

GO Terms for genes affiliated with Hypoalphalipoproteinemia

Sources:
16Gene Ontology
See all sources

Cellular components related to Hypoalphalipoproteinemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1spherical high-density lipoprotein particleGO:0343669.9APOA2, APOC3, APOA1
2endocytic vesicle lumenGO:0716829.9APOB, APOA1
3intermediate-density lipoprotein particleGO:0343639.8APOC3, APOB
4chylomicronGO:0426279.6LPL, APOB, APOA2, APOC3
5high-density lipoprotein particleGO:0343649.5CETP, LIPC, APOA2, APOA1, LCAT
6low-density lipoprotein particleGO:0343629.5APOB, LDLR
7very-low-density lipoprotein particleGO:0343619.4LPL, APOB, APOA2, APOC3, APOA1
8early endosomeGO:0057699.2APOA1, LDLR, APOA2, APOB, APOC3
9extracellular spaceGO:0056158.2CETP, APOA1, LCAT, APOB, APOC3, LPL
10extracellular regionGO:0055767.7APOB, LCAT, CETP, ACE, PLTP, APOA1

Biological processes related to Hypoalphalipoproteinemia according to GeneCards/GeneDecks:

(show all 48)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of lipase activityGO:06019210.4APOA1, APOA2
2regulation of intestinal cholesterol absorptionGO:03030010.4APOA1, APOA2
3negative regulation of cholesterol importGO:06062110.4APOC3, APOA2
4negative regulation of cytokine secretion involved in immune responseGO:00274010.4APOA1, APOA2
5protein oxidationGO:01815810.4APOA2, APOA1
6high-density lipoprotein particle clearanceGO:03438410.3APOA2, APOA1
7peptidyl-methionine modificationGO:01820610.3APOA2, APOA1
8cholesterol importGO:07050810.3LDLR, APOA1
9positive regulation of cholesterol esterificationGO:01087310.3APOA1, APOA2
10high-density lipoprotein particle assemblyGO:03438010.2APOA1, ABCA1, APOA2
11negative regulation of very-low-density lipoprotein particle remodelingGO:01090310.2APOC3, APOA1, APOA2
12phosphatidylcholine biosynthetic processGO:00665610.2APOA1, APOA2, LCAT
13regulation of Cdc42 protein signal transductionGO:03248910.2ABCA1, APOC3, APOA1
14chylomicron remnant clearanceGO:03438210.2APOC3, LIPC
15phospholipid homeostasisGO:05509110.2CETP, APOA1, ABCA1
16triglyceride mobilizationGO:00664210.2APOC3, APOB
17lipoprotein catabolic processGO:04215910.2APOB, LDLR
18negative regulation of cholesterol storageGO:01088710.2PPARA, ABCA1
19lipoprotein biosynthetic processGO:04215810.1APOB, LCAT, APOA1
20phospholipid transportGO:01591410.1CETP, LDLR
21negative regulation of macrophage derived foam cell differentiationGO:01074510.0ABCA1, PPARA, CETP
22positive regulation of cholesterol storageGO:01088610.0APOB, LPL
23phospholipid effluxGO:03370010.0APOA1, ABCA1, APOA2, APOC3
24very-low-density lipoprotein particle assemblyGO:03437910.0APOB, APOC3
25triglyceride metabolic processGO:0066419.9LPL, APOC3, CETP, APOA2
26low-density lipoprotein particle clearanceGO:0343839.9LDLR, APOB
27very-low-density lipoprotein particle remodelingGO:0343729.9LIPC, LPL, LCAT, CETP
28positive regulation of macrophage derived foam cell differentiationGO:0107449.9LPL, APOB
29lipid transportGO:0068699.8PLTP, LPA, CETP
30low-density lipoprotein particle remodelingGO:0343749.8CETP, LIPC, APOB, APOA2
31lipoprotein transportGO:0429539.8APOB, APOC3
32triglyceride catabolic processGO:0194339.7LIPC, LPL, APOB, APOC3
33negative regulation of lipid catabolic processGO:0509959.7APOC3, APOA2
34cholesterol effluxGO:0333449.7APOA1, APOC3, APOA2, APOB, ABCA1
35triglyceride homeostasisGO:0703289.7CETP, LIPC, LPL, APOC3, APOA1
36cholesterol transportGO:0303019.6APOB, APOA1, LCAT, CETP, LDLR
37response to drugGO:0424939.6APOA1, APOC3, LPL, APOA2
38retinoid metabolic processGO:0015239.5APOA2, LDLR, LPL, APOB, APOC3
39cellular lipid metabolic processGO:0442559.5PPARA, ABCA1, SLC25A20, APOA2, APOA1
40high-density lipoprotein particle remodelingGO:0343759.5LCAT, APOC3, APOA2, CETP, APOA1, LIPC
41lipid metabolic processGO:0066299.5PLTP, LPA, PPARA, LDLR
42receptor-mediated endocytosisGO:0068989.5CETP, APOB, LPA, LDLR
43phototransduction, visible lightGO:0076039.3APOA1, LDLR, APOC3, APOA2, APOB, LPL
44reverse cholesterol transportGO:0436919.3CETP, LCAT, ABCA1, LIPC, APOA2, APOC3
45cholesterol metabolic processGO:0082038.7APOA1, LCAT, APOC3, APOA2, APOB, LIPC
46cholesterol homeostasisGO:0426328.7LDLR, CETP, ABCA1, LIPC, APOB, APOA2
47lipoprotein metabolic processGO:0421577.9APOA2, APOA1, APOC3, LPL, ABCA1, LCAT
48small molecule metabolic processGO:0442816.6APOA1, APOC3, GBA, APOA2, APOB, PPARA

Molecular functions related to Hypoalphalipoproteinemia according to GeneCards/GeneDecks:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1apolipoprotein receptor bindingGO:03419010.3APOA1, APOA2
2apolipoprotein A-I bindingGO:03418610.2LCAT, ABCA1
3phosphatidylcholine-sterol O-acyltransferase activator activityGO:06022810.2APOA1, APOA2
4triglyceride bindingGO:01712910.2LPL, CETP
5high-density lipoprotein particle bindingGO:00803510.2APOA1, APOA2
6high-density lipoprotein particle receptor bindingGO:07065310.1APOA1, APOA2, APOC3
7lipase inhibitor activityGO:05510210.1APOA2, APOC3, APOA1
8phospholipid transporter activityGO:00554810.1APOA1, CETP, ABCA1
9phosphatidylcholine bindingGO:03121010.0APOA2, CETP
10phospholipase activityGO:00462010.0LIPC, LPL
11triglyceride lipase activityGO:0048069.9LPL, LIPC
12low-density lipoprotein particle bindingGO:0301699.8LDLR, LIPC
13lipid bindingGO:0082899.7PLTP, APOA2, PPARA, CETP
14lipid transporter activityGO:0053199.7APOA2, CETP
15cholesterol bindingGO:0154859.7APOC3, APOA2, CETP, APOA1, ABCA1
16cholesterol transporter activityGO:0171279.6ABCA1, APOB, APOA2, CETP, APOA1
17apolipoprotein bindingGO:0341859.6ABCA1, LPL, LPA, LIPC
18phospholipid bindingGO:0055439.5ABCA1, APOA2, APOC3, APOA1, APOB
19heparin bindingGO:0082019.3LIPC, APOB, LPL, LPA

Products for genes affiliated with Hypoalphalipoproteinemia

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Sources for Hypoalphalipoproteinemia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet