MCID: HYP056
MIFTS: 66

Hypoglycemia malady

Summaries for Hypoglycemia

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33MedlinePlus, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Hypoglycemia means low blood glucose, or blood sugar. your body needs glucose to have enough energy. after you eat, your blood absorbs glucose. if you eat more sugar than your body needs, your muscles, and liver store the extra. when your blood sugar begins to fall, a hormone tells your liver to release glucose. in most people, this raises blood sugar. if it doesn't, you have hypoglycemia, and your blood sugar can be dangerously low. signs include hunger shakiness dizziness confusion difficulty speaking feeling anxious or weak in people with diabetes, hypoglycemia is often a side effect of diabetes medicines. eating or drinking something with carbohydrates can help. if it happens often, your health care provider may need to change your treatment plan. you can also have low blood sugar without having diabetes. causes include certain medicines or diseases, hormone or enzyme deficiencies, and tumors. laboratory tests can help find the cause. the kind of treatment depends on why you have low blood sugar. nih: national institute of diabetes and digestive and kidney diseases

MalaCards: Hypoglycemia, also known as hypoglycaemia, is related to hyperinsulinemic hypoglycemia and diabetes mellitus. An important gene associated with Hypoglycemia is ABCC8 (ATP-binding cassette, sub-family C (CFTR/MRP), member 8), and among its related pathways are Metabolism and FOXA2 and FOXA3 transcription factor networks. The drugs diazoxide and glucagon and the compounds glucose and glutamate have been mentioned in the context of this disorder. Affiliated tissues include liver, brain and testes, and related mouse phenotypes are homeostasis/metabolism and liver/biliary system.

Wikipedia:63 Hypoglycemia (also spelled hypoglycaemia or hypoglycæmia, not to be confused with hyperglycemia) is a... more...

Aliases & Classifications for Hypoglycemia

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8Disease Ontology, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 56SNOMED-CT, 39NCIt, 27ICD9CM, 34MeSH
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Aliases & Descriptions:

hypoglycemia 8 10 44 33 60
hypoglycaemia 8


External Ids:

Disease Ontology8 DOID:9993
NCIt39 C3126
ICD9CM27 251.2
MeSH34 D007003

Related Diseases for Hypoglycemia

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17GeneCards, 18GeneDecks
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Diseases related to Hypoglycemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 355)
idRelated DiseaseScoreTop Affiliating Genes
1hyperinsulinemic hypoglycemia31.4ABCC8, IGF2, INS
2diabetes mellitus30.9PYGL, GCG, KCNJ11, GCK, ABCC8, INSR
3pancreatitis30.8INS, GCG
4insulinoma30.8HNF4A, G6PC, IGF2, GLUD1, INS, INSR
5hyperinsulinism30.7KCNJ11, GCG, GCK, HADH, IGF2, GLUD1
6hyperglycemia30.7GCK, GCG, FBP1, KCNJ11, INS, INSR
7familial hyperinsulinism30.6KCNJ11, GCK, HADH, GLUD1, ABCC8
8lactic acidosis30.5INS, G6PC, GCG
9hepatitis30.4HNF4A, GLUD1
10type 2 diabetes mellitus30.4GCK, GCG, KCNJ11, HNF4A, G6PC, INS
11glycogen storage disease30.4G6PC, GCG, PYGL
12dumping syndrome30.3GCG
13obesity30.2INSR, INS, KCNJ11, GCG, CRH, GCK
14ischemia30.2GCK, SLC16A1, ABCC8, GLUD1, G6PC, GCG
15maturity-onset diabetes of the young30.2INS, HNF4A, GCK, KCNJ11
16beckwith-wiedemann syndrome30.1ABCC8, IGF2
17hypopituitarism30.1GCG, CRH, INS
18galactosemia30.1INS, HNF4A, GCG, GLUD1
19myocardial infarction30.1GCG
20diarrhea30.1INS, GCG
21anorexia nervosa30.0GCG, CRH
22gestational diabetes29.8INSR, INS, HNF4A, GCK, GCG, KCNJ11
23liver cirrhosis29.8INSR, GLUD1, G6PC, HNF4A, GCG
24adenocarcinoma29.8G6PC, INSR, SLC16A1, HNF4A
25acromegaly29.8CRH, INS, IGF2
26glycogen storage disease vi29.8G6PC, PYGL
27cushing's syndrome29.8CRH, INS
28hypoglycemic coma29.8INS, IGF2
29acute myocardial infarction29.8GCG
30hyperinsulinism-hyperammonemia syndrome29.8GLUD1
31laron syndrome29.8IGF2
32hypertension29.7INSR, INS, CRH
33polycystic ovary syndrome29.7INSR, IGF2, INS
34colon cancer29.7HNF4A, IGF2, GCG, SLC16A1
35eating disorder29.7INS
36adenoma29.6G6PC, GCG, CRH, IGF2, INS, INSR
37neonatal diabetes mellitus29.6INS, KCNJ11, ABCC8, GCK
38glucose intolerance29.6GCG, GCK, INS, INSR
39hepatoblastoma29.6HNF4A, IGF2, INSR
403-hydroxyacyl-coa dehydrogenase deficiency29.6HADH
41pituitary adenoma29.6CRH, ABCC8
42hyperuricemia29.6GCK, G6PC, INS
43amenorrhea29.6CRH, INS
44myotonic dystrophy29.6INSR
45donohue syndrome29.6INSR, INS
46chronic fatigue syndrome29.6CRH
47atherosclerosis29.6HNF4A, INS
48islet cell tumor10.6
49type 1 diabetes mellitus10.4
50hemangiopericytoma10.4

Graphical network of the top 20 diseases related to Hypoglycemia:



Diseases related to hypoglycemia

Clinical Features for Hypoglycemia

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Drugs & Therapeutics for Hypoglycemia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Hypoglycemia

Drug clinical trials:

Search ClinicalTrials for Hypoglycemia

Search NIH Clinical Center for Hypoglycemia

Search CenterWatch for Hypoglycemia

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Hypoglycemia

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Anatomical Context for Hypoglycemia

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32MalaCards
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MalaCards organs/tissues related to Hypoglycemia:

32
Liver, Brain, Testes, Kidney, Pituitary, Pancreas, Endothelial, Thyroid, Pancreatic islet, Breast, Cortex, Heart, Bone, Lung, Hypothalamus, B cells, Spleen, Ovary, Skeletal muscle, Adrenal cortex, Parietal lobe, Colon, Cingulate cortex, T cells, Monocytes, Uterus, Spinal cord, Bone marrow

Animal Models for Hypoglycemia or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Hypoglycemia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537611.5ACADL, KCNJ11, GCG, GCK, HNF4A, HADH
2MP:000537011.1GCK, HNF4A, G6PC, GYS2, IGF2, INS
3MP:000537911.1HADH, GCK, GCG, KCNJ11, CRH, IGF2
4MP:000537811.0HADH, HNF4A, GCK, GCG, KCNJ11, G6PC
5MP:000536710.9GCG, GCK, HADH, G6PC, IGF2, INS
6MP:000538510.9GYS2, IGF2, INS, INSR, SLC22A5, ACADM
7MP:001076810.7KCNJ11, GCG, GCK, HNF4A, G6PC, IGF2

Publications for Hypoglycemia

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50PubMed
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Articles related to Hypoglycemia:

(show top 50)    (show all 1350)
idTitleAuthorsYear
1
Toward defining a cutoff score for elevated fear of hypoglycemia on the hypoglycemia fear survey worry subscale in patients with type 2 diabetes. (23990513)
2014
2
Hypoglycemia during rapid methadone dose escalation. (23709301)
2013
3
Central pontine and extra-pontine myelinolysis after correction of severe hypoglycemia. (23728716)
2013
4
Nonislet cell tumor hypoglycemia. (24194988)
2013
5
Computerization of the Yale insulin infusion protocol and potential insights into causes of hypoglycemia with intravenous insulin. (23289409)
2013
6
Hindbrain Lactostasis Regulates Hypothalamic AMPK Activity and Hypothalamic Metabolic Neurotransmitter mRNA and Protein Responses to Hypoglycemia. (24381179)
2013
7
Effect of different blood glucose target levels on the incidence of hypoglycemia during insulin therapy in the intensive care unit. (23035699)
2013
8
Minireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes. (22166985)
2012
9
Lactate infusion during euglycemia but not hypoglycemia reduces subsequent food intake in healthy men. (22314041)
2012
10
Site-specific effects of intracranial estradiol administration on recurrent insulin-induced hypoglycemia in the ovariectomized female rat. (22572755)
2012
11
Risk factors for inpatient hypoglycemia during subcutaneous insulin therapy in non-critically ill patients with type 2 diabetes. (23063027)
2012
12
Severe hypoglycemia symptoms, antecedent behaviors, immediate consequences and association with glycemia medication usage: Secondary analysis of the ACCORD clinical trial data. (22646230)
2012
13
Recurrent solitary fibrous tumor of the pleura with malignant transformation and non-islet cell tumor-induced hypoglycemia due to paraneoplastic overexpression and secretion of high-molecular-weight insulin-like growth Factor II. (23207122)
2012
14
Profound hypoglycemia presents with reversible symmetrical ADC signal changes isolated to eloquent cortex of the parietal lobe. (22306171)
2012
15
Hypoglycemia in critically ill adults--association yes, causation not proven. (22188732)
2011
16
Hyperinsulinemic hypoglycemia evolving to gestational diabetes and diabetes mellitus in a family carrying the inactivating ABCC8 E1506K mutation. (20042013)
2010
17
Persistent hyperinsulinemic hypoglycemia of infancy associated with congenital neuroblastoma: a case report. (20572382)
2010
18
Delay in blood glucose monitoring during an insulin infusion protocol is associated with increased risk of hypoglycemia in intensive care units. (19670374)
2009
19
Severe hypoglycemia after initiation of anti-tumor necrosis factor therapy with etanercept in a patient with generalized pustular psoriasis and type 2 diabetes mellitus. (19389539)
2009
20
Divergent effects of hyper- and hypoglycemia on circulating vascular endothelial growth factor in humans. (18078864)
2008
21
Effects of oral carbohydrate on autonomic nervous system counterregulatory responses during hyperinsulinemic hypoglycemia and euglycemia. (18612042)
2008
22
Hypoglycemia due to an insulin binding antibody in a patient with an IgA-kappa myeloma. (17405845)
2007
23
Islet hyperplasia in adults: challenge to preoperatively diagnose non-insulinoma pancreatogenic hypoglycemia syndrome. (16555022)
2006
24
Protein-sensitive hypoglycemia without leucine sensitivity in hyperinsulinism caused by K(ATP) channel mutations. (16860127)
2006
25
Glucocorticoid therapy ameliorated hypoglycemia in insulin-like growth factor-II-producing solitary fibrous tumor. (16702745)
2006
26
Hypoglycemia due to adrenal insufficiency secondary to corticotropin-releasing hormone deficiency]. (16266629)
2005
27
Measurement of plasma chromogranin A concentrations for assessment of stress responses in dogs with insulin-induced hypoglycemia. (16273918)
2005
28
Exercise and newer insulins: how much glucose supplement to avoid hypoglycemia? (16118572)
2005
29
Solitary fibrous tumor in the pelvic cavity with hypoglycemia: report of a case. (15674506)
2005
30
A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene. (15161766)
2004
31
Multiple extracranial metastases from a meningeal hemangiopericytoma and severe hypoglycemia: a case report]. (15227844)
2004
32
Megestrol acetate promotes euglycemia and appetite in a child with persistent hyperinsulinemic hypoglycemia of infancy. (15124853)
2004
33
Impact of hypoglycemia and diabetes on CNS: correlation of mitochondrial oxidative stress with DNA damage. (15228097)
2004
34
Fasting hypoglycemia in solitary fibrous tumor of the peritoneum: a diagnostic clue for an emergent situation. (15290507)
2003
35
Laparoscopic identification and removal of focal lesions in persistent hyperinsulinemic hypoglycemia of infancy. (14689291)
2003
36
Severe and prolonged hypoglycemia triggered by long-acting octreotide in a patient with malignant mesenchymal tumor: case report. (12678421)
2003
37
Hypoglycemia associated with the production of insulin-like growth factor (IGF)-II by a hemangiopericytoma]. (12571793)
2003
38
Extracellular ATP and nerve growth factor intensify hypoglycemia-induced cell death in primary neurons: role of P2 and NGFRp75 receptors. (12437584)
2002
39
Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats. (10206446)
1999
40
Severe and recurrent fasting hypoglycemia due to growth hormone deficiency? (10493328)
1999
41
Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy. (10567373)
1999
42
Inactivation of the first nucleotide-binding fold of the sulfonylurea receptor, and familial persistent hyperinsulinemic hypoglycemia of infancy. (8751851)
1996
43
Corticotropin responses to hypoglycemia and hypotension during ovine pregnancy. (8304539)
1994
44
Increased epinephrine and skeletal muscle responses to hypoglycemia in non-insulin-dependent diabetes mellitus. (8200993)
1994
45
Levels of beta-endorphin in serum of patients with chronic renal failure treated with hemodialysis during a test which stimulates hypoglycemia after insulin]. (8327371)
1993
46
Effect of oral clonidine, insulin-induced hypoglycemia and exercise on plasma GHRH levels in short-stature children. (2106191)
1990
47
The juvenile human endocrine pancreas: normal v idiopathic hyperinsulinemic hypoglycemia. (6400628)
1984
48
Remission of hypoglycemia after partial resection of a metastatic islet cell tumor. (208422)
1978
49
Spontaneous fasting hypoglycemia: basal levels of plasma free fatty acids and glycerol, blood ketone bodies, serum cholesterol and plasma growth hormone. (668979)
1978
50
SPONTANEOUS hypoglycemia with abdominal spindle-cell sarcoma. (13857105)
1960

Genetic Variations for Hypoglycemia

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Expression for genes affiliated with Hypoglycemia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypoglycemia

Search GEO for disease gene expression data for Hypoglycemia.

Pathways for genes affiliated with Hypoglycemia

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Sources:
53Reactome, 29KEGG, 37NCBI BioSystems Database, 12EMD Millipore, 49PharmGKB, 51QIAGEN, 4Cell Signaling Technology
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Pathways related to Hypoglycemia according to GeneCards/GeneDecks:

(show all 27)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.9KCNJ11, GCG, GCK, PYGL, HADH, G6PC
210.9ACADM, KCNJ11, GCK, HNF4A, HADH, G6PC
3
Translation Insulin regulation of translation
Hide members
10.8GCK, PYGL, G6PC, FBP1, GYS2, INS
4
Hide members
10.8KCNJ11, GCK, HNF4A, INS, INSR, ABCC8
5
Hide members
10.8INS, ABCC8, SLC25A20, SLC16A1, ACADM, ACADL
6
Hide members
10.7GCK, PYGL, G6PC, FBP1, GYS2
710.7KCNJ11, GCG, GCK, INS, ABCC8
8
Hide members
10.7SLC16A1, SLC22A5, ABCC8, G6PC, GCK
9
Hide members
10.7INSR, IGF2, GYS2, PYGL, GCG
1010.7GCG, HNF4A, GLUD1, INS, INSR
11
Hide members
10.7ACADL, ACADM, SLC25A20, HADH
12
Hide members
10.7HADH, SLC25A20, ACADM, ACADL
13
Hide members
10.7GCK, PYGL, G6PC, GYS2
14
Galactose metabolism
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10.7GCK, PYGL, G6PC, GYS2
15
Hide members
10.7KCNJ11, GCG, INS, ABCC8
16
Hide members
10.7INSR, INS, HNF4A, GCK
17
Development Leptin signaling via PI3K-dependent pathway
Hide members
10.6ABCC8, GYS2, KCNJ11
18
Hide members
10.6GCK, G6PC, FBP1
19
Hide members
10.6GYS2, FBP1, PYGL
20
Hide members
10.6INS, HNF4A, GCK
2110.6HNF4A, GYS2, INSR
22
Hide members
10.6INSR, INS, IGF2
23
Hide members
10.6IGF2, INS, INSR
2410.6ABCC8, KCNJ11
25
Hide members
10.6HADH, ACADM
2610.6GCG, CRH
27
Hide members
10.6INS, INSR

Compounds for genes affiliated with Hypoglycemia

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Sources:
44Novoseek, 24HMDB, 11DrugBank, 59Tocris Bioscience, 28IUPHAR, 49PharmGKB, 2BitterDB
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Compounds related to Hypoglycemia according to GeneCards/GeneDecks:

(show top 50)    (show all 126)
idCompoundScoreTop Affiliating Genes
1glucose4411.8KCNJ11, GCG, GCK, HNF4A, PYGL, HADH
2glutamate4411.6CRH, IGF2, GLUD1, INS, INSR, ABCC8
3arginine4411.6SLC22A5, KCNJ11, GCG, GCK, G6PC, CRH
4fatty acid4411.4GCG, GCK, HNF4A, GLUD1, ABCC8, SLC25A20
5glycogen44 2412.4G6PC, IGF2, ABCC8, INSR, INS, HNF4A
6glutamine4411.4GCG, G6PC, IGF2, GLUD1, INSR, KCNJ11
7lipid4411.3SLC25A20, ABCC8, INS, GCG, ACADM, ACADL
8carnitine4411.3IGF2, GLUD1, ACADL, ACADM, SLC22A5, SLC25A20
9glycerol44 11 2413.3GCG, HNF4A, CRH, GLUD1, INS, INSR
10alanine4411.3GCK, HNF4A, GCG, INS, GLUD1, IGF2
11katp4411.3KCNJ11, GCK, GCG, GLUD1, HADH, INS
12lactate4411.3IGF2, INS, SLC16A1, ACADM, GLUD1, G6PC
13creatinine4411.3CRH, IGF2, GLUD1, GCG, INSR, INS
14c-peptide4411.3IGF2, KCNJ11, GCG, GCK, HNF4A, INS
15diazoxide44 59 28 1114.2INS, GLUD1, HADH, ABCC8, KCNJ11, GCK
16sulfonylurea4411.2GCK, ABCC8, GLUD1, GCG, INS, KCNJ11
17tolbutamide44 49 28 1114.2ABCC8, GLUD1, GCK, GCG, KCNJ11, INS
18dexamethasone44 49 28 1114.2GCK, HNF4A, CRH, G6PC, INSR, GLUD1
19glibenclamide44 28 49 5914.2KCNJ11, GCG, ABCC8, INSR, INS, CRH
20metformin44 49 1113.2GCK, INS, INSR, ABCC8, KCNJ11, GCG
212-deoxyglucose44 1112.2GCG, IGF2, GCK, G6PC, INSR, INS
22acyl-coa4411.2HADH, HNF4A, ACADL, ACADM, SLC25A20, GLUD1
23glimepiride44 49 1113.2ABCC8, INSR, INS, GCG, KCNJ11
24leucine4411.1HNF4A, GCK, HADH, G6PC, GLUD1, ABCC8
25streptozotocin4411.1GCK, INSR, GCG, INS, G6PC
26octreotide44 59 28 1114.1GCG, CRH, IGF2, INSR, INS
27repaglinide44 49 1113.1GCG, INS, KCNJ11, ABCC8
28beta-hydroxybutyrate4411.1GLUD1, INS, SLC16A1, G6PC
29gliclazide44 49 1113.1KCNJ11, INS, INSR, ABCC8
30rapamycin4411.1GCG, IGF2, INS, INSR, GLUD1, G6PC
31verapamil44 49 28 11 2415.0SLC22A5, KCNJ11, IGF2, INSR, CRH
32nateglinide44 49 1113.0ABCC8, INS, GCG, SLC16A1
33cysteine4411.0GLUD1, ABCC8, GCG, IGF2, CRH, HNF4A
34glucose 6-phosphate44 2412.0GCK, GLUD1, PYGL, G6PC
35meglitinide4411.0INS, ABCC8, GCG
36aicar44 11 2413.0INS, INSR, GCK, G6PC
37chromium picolinate4411.0INS, INSR, GCK
38palmitate4410.9HNF4A, INS, ACADM
39phosphoenolpyruvate44 1111.9G6PC, GCK, HNF4A, GLUD1
40preproinsulin4410.9INSR, INS, GCK
41moxonidine4410.9SLC22A5, INSR, INS
42i-app4410.9GCG, GCK, INS
43pyruvate4410.8GCK, G6PC, HNF4A, SLC16A1, GLUD1
44fructose-6-phosphate44 1111.8FBP1, G6PC, GCK
45incretin4410.8GCG, GCK, INS
46dhea4410.7G6PC, CRH, IGF2, INS
47epinephrine44 11 2412.7INSR, CRH, SLC22A5, GCG, INS
48pioglitazone44 49 28 1113.7INS, INSR, IGF2, GCG
49serine4410.6CRH, IGF2, GCG, GLUD1, INS, INSR
50chloramphenicol44 2 1112.6HNF4A, CRH, IGF2, INSR, ACADM

GO Terms for genes affiliated with Hypoglycemia

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Sources:
16Gene Ontology
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Cellular components related to Hypoglycemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrionGO:00573910.8ACADL, KCNJ11, GCK, HADH, GLUD1, SLC25A20
2secretory granule lumenGO:03477410.6INS, GCG
3mitochondrial matrixGO:00575910.4ACADL, ACADM, GLUD1, HADH

Biological processes related to Hypoglycemia according to GeneCards/GeneDecks:

(show all 27)
idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:04428111.6ACADL, KCNJ11, GCG, GCK, PYGL, HADH
2carbohydrate metabolic processGO:00597511.2GCK, PYGL, G6PC, FBP1, GYS2, INSR
3regulation of insulin secretionGO:05079611.2KCNJ11, GCG, GCK, HNF4A, INS, ABCC8
4glucose homeostasisGO:04259311.1GCK, HNF4A, PYGL, G6PC, INS, INSR
5glucose metabolic processGO:00600611.1KCNJ11, PYGL, FBP1, GYS2, IGF2, INS
6positive regulation of glycogen biosynthetic processGO:04572511.0GCK, IGF2, INS, INSR
7energy reserve metabolic processGO:00611211.0KCNJ11, GCG, INS, ABCC8
8glycogen biosynthetic processGO:00597811.0ACADM, GYS2, GCK
9positive regulation of glycolysisGO:04582111.0GCK, INS, INSR
10cellular lipid metabolic processGO:04425511.0ACADL, ACADM, SLC25A20, HADH
11fatty acid beta-oxidationGO:00663510.9HADH, ACADM, ACADL
12positive regulation of mitosisGO:04584010.9INSR, INS, IGF2
13endocrine pancreas developmentGO:03101810.9GCK, HNF4A, INS
14positive regulation of respiratory burstGO:06026710.9INS, INSR
15carnitine metabolic process, CoA-linkedGO:01925410.9ACADM, ACADL
16glucose transportGO:01575810.9GCK, G6PC, INS
17fatty acid beta-oxidation using acyl-CoA dehydrogenaseGO:03353910.8ACADM, ACADL
18negative regulation of epinephrine secretionGO:03281110.8GCK, CRH
19positive regulation of MAPK cascadeGO:04341010.8INSR, INS, IGF2
20positive regulation of protein kinase B signaling cascadeGO:05189710.8IGF2, INS, INSR
21positive regulation of insulin receptor signaling pathwayGO:04662810.8INS, IGF2
22negative regulation of gluconeogenesisGO:04572110.7INS, GCK
23positive regulation of calcium ion importGO:09028010.6GCG, CRH
24transmembrane transportGO:05508510.6GCK, G6PC, ABCC8, SLC22A5, SLC16A1
25regulation of gluconeogenesisGO:00611110.6FBP1, ACADM
26positive regulation of insulin secretion involved in cellular response to glucose stimulusGO:03577410.6CRH, GCG
27positive regulation of protein phosphorylationGO:00193410.3INSR, IGF2, CRH

Molecular functions related to Hypoglycemia according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00517910.8GCG, CRH, IGF2, INS
2insulin-like growth factor receptor bindingGO:00515910.8INSR, INS, IGF2
3identical protein bindingGO:04280210.8GCG, FBP1, GLUD1, INS, ACADM
4glucose bindingGO:00553610.7PYGL, GCK
5AMP bindingGO:01620810.6FBP1, PYGL
6NAD+ bindingGO:07040310.6GLUD1, HADH
7ATP bindingGO:00552410.5KCNJ11, GCK, PYGL, GLUD1, INSR, ABCC8
8acyl-CoA dehydrogenase activityGO:00399510.5ACADL, ACADM

Products for genes affiliated with Hypoglycemia

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Sources for Hypoglycemia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet