MCID: HYP056
MIFTS: 66

Hypoglycemia malady

Summaries for Hypoglycemia

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33MedlinePlus, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Hypoglycemia means low blood glucose, or blood sugar. your body needs glucose to have enough energy. after you eat, your blood absorbs glucose. if you eat more sugar than your body needs, your muscles, and liver store the extra. when your blood sugar begins to fall, a hormone tells your liver to release glucose. in most people, this raises blood sugar. if it doesn't, you have hypoglycemia, and your blood sugar can be dangerously low. signs include hunger shakiness dizziness confusion difficulty speaking feeling anxious or weak in people with diabetes, hypoglycemia is often a side effect of diabetes medicines. eating or drinking something with carbohydrates can help. if it happens often, your health care provider may need to change your treatment plan. you can also have low blood sugar without having diabetes. causes include certain medicines or diseases, hormone or enzyme deficiencies, and tumors. laboratory tests can help find the cause. the kind of treatment depends on why you have low blood sugar. nih: national institute of diabetes and digestive and kidney diseases

MalaCards: Hypoglycemia, also known as hypoglycaemia, is related to hyperinsulinemic hypoglycemia and diabetes mellitus. An important gene associated with Hypoglycemia is ABCC8 (ATP-binding cassette, sub-family C (CFTR/MRP), member 8), and among its related pathways are Metabolism and FOXA2 and FOXA3 transcription factor networks. The drugs diazoxide and glucagon and the compounds glucose and glutamate have been mentioned in the context of this disorder. Affiliated tissues include liver, brain and testes, and related mouse phenotypes are homeostasis/metabolism and liver/biliary system.

Wikipedia:63 Hypoglycemia (also spelled hypoglycaemia or hypoglycæmia, not to be confused with hyperglycemia) is a... more...

Aliases & Classifications for Hypoglycemia

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8Disease Ontology, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 56SNOMED-CT, 39NCIt, 27ICD9CM, 34MeSH
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Aliases & Descriptions:

hypoglycemia 8 10 44 33 60
hypoglycaemia 8


External Ids:

Disease Ontology8 DOID:9993
NCIt39 C3126
ICD9CM27 251.2
MeSH34 D007003

Related Diseases for Hypoglycemia

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17GeneCards, 18GeneDecks
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Diseases related to Hypoglycemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 355)
idRelated DiseaseScoreTop Affiliating Genes
1hyperinsulinemic hypoglycemia31.4ABCC8, IGF2, INS
2diabetes mellitus30.9PYGL, GCG, KCNJ11, GCK, ABCC8, INSR
3pancreatitis30.8INS, GCG
4insulinoma30.8HNF4A, G6PC, IGF2, GLUD1, INS, INSR
5hyperinsulinism30.7KCNJ11, GCG, GCK, HADH, IGF2, GLUD1
6hyperglycemia30.7GCK, GCG, FBP1, KCNJ11, INS, INSR
7familial hyperinsulinism30.6KCNJ11, GCK, HADH, GLUD1, ABCC8
8lactic acidosis30.5INS, G6PC, GCG
9hepatitis30.4HNF4A, GLUD1
10type 2 diabetes mellitus30.4GCK, GCG, KCNJ11, HNF4A, G6PC, INS
11glycogen storage disease30.4G6PC, GCG, PYGL
12dumping syndrome30.3GCG
13obesity30.2INSR, INS, KCNJ11, GCG, CRH, GCK
14ischemia30.2GCK, SLC16A1, ABCC8, GLUD1, G6PC, GCG
15maturity-onset diabetes of the young30.2INS, HNF4A, GCK, KCNJ11
16beckwith-wiedemann syndrome30.1ABCC8, IGF2
17hypopituitarism30.1GCG, CRH, INS
18galactosemia30.1INS, HNF4A, GCG, GLUD1
19myocardial infarction30.1GCG
20diarrhea30.1INS, GCG
21anorexia nervosa30.0GCG, CRH
22gestational diabetes29.8INSR, INS, HNF4A, GCK, GCG, KCNJ11
23liver cirrhosis29.8INSR, GLUD1, G6PC, HNF4A, GCG
24adenocarcinoma29.8G6PC, INSR, SLC16A1, HNF4A
25acromegaly29.8CRH, INS, IGF2
26glycogen storage disease vi29.8G6PC, PYGL
27cushing's syndrome29.8CRH, INS
28hypoglycemic coma29.8INS, IGF2
29acute myocardial infarction29.8GCG
30hyperinsulinism-hyperammonemia syndrome29.8GLUD1
31laron syndrome29.8IGF2
32hypertension29.7INSR, INS, CRH
33polycystic ovary syndrome29.7INSR, IGF2, INS
34colon cancer29.7HNF4A, IGF2, GCG, SLC16A1
35eating disorder29.7INS
36adenoma29.6G6PC, GCG, CRH, IGF2, INS, INSR
37neonatal diabetes mellitus29.6INS, KCNJ11, ABCC8, GCK
38glucose intolerance29.6GCG, GCK, INS, INSR
39hepatoblastoma29.6HNF4A, IGF2, INSR
403-hydroxyacyl-coa dehydrogenase deficiency29.6HADH
41pituitary adenoma29.6CRH, ABCC8
42hyperuricemia29.6GCK, G6PC, INS
43amenorrhea29.6CRH, INS
44myotonic dystrophy29.6INSR
45donohue syndrome29.6INSR, INS
46chronic fatigue syndrome29.6CRH
47atherosclerosis29.6HNF4A, INS
48islet cell tumor10.6
49type 1 diabetes mellitus10.4
50hemangiopericytoma10.4

Graphical network of the top 20 diseases related to Hypoglycemia:



Diseases related to hypoglycemia

Clinical Features for Hypoglycemia

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Drugs & Therapeutics for Hypoglycemia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Hypoglycemia

Drug clinical trials:

Search ClinicalTrials for Hypoglycemia

Search NIH Clinical Center for Hypoglycemia

Search CenterWatch for Hypoglycemia

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Hypoglycemia

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Anatomical Context for Hypoglycemia

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32MalaCards
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MalaCards organs/tissues related to Hypoglycemia:

32
Liver, Brain, Testes, Kidney, Pituitary, Pancreas, Endothelial, Thyroid, Pancreatic islet, Breast, Cortex, Heart, Bone, Lung, Hypothalamus, B cells, Spleen, Ovary, Skeletal muscle, Adrenal cortex, Parietal lobe, Colon, Cingulate cortex, T cells, Monocytes, Uterus, Spinal cord, Bone marrow

Animal Models for Hypoglycemia or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Hypoglycemia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537611.5ACADL, KCNJ11, GCG, GCK, HNF4A, HADH
2MP:000537011.1GCK, HNF4A, G6PC, GYS2, IGF2, INS
3MP:000537911.1HADH, GCK, GCG, KCNJ11, CRH, IGF2
4MP:000537811.0HADH, HNF4A, GCK, GCG, KCNJ11, G6PC
5MP:000536710.9GCG, GCK, HADH, G6PC, IGF2, INS
6MP:000538510.9GYS2, IGF2, INS, INSR, SLC22A5, ACADM
7MP:001076810.7KCNJ11, GCG, GCK, HNF4A, G6PC, IGF2

Publications for Hypoglycemia

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50PubMed
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Articles related to Hypoglycemia:

(show top 50)    (show all 1350)
idTitleAuthorsYear
1
Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: A potential new approach for the treatment of hyperinsulinemic hypoglycemia. (24423625)
2014
2
Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins. (22934852)
2013
3
Impact of the "Diabetes Interactive Diary" telemedicine system on metabolic control, risk of hypoglycemia, and quality of life: a randomized clinical trial in type 1 diabetes. (23844569)
2013
4
Management of Non-Islet-Cell Tumor Hypoglycemia: A Clinical Review. (24423303)
2013
5
Glucagon-like peptide 1 reduces endothelial dysfunction, inflammation, and oxidative stress induced by both hyperglycemia and hypoglycemia in type 1 diabetes. (23564922)
2013
6
Severe hypoglycemia-induced lethal cardiac arrhythmias are mediated by sympathoadrenal activation. (23835337)
2013
7
Case studies in hypoglycemia. When is it safe to leave these patients at home? (24073511)
2013
8
Hormonal response to a mixed-meal challenge after reversal of gastric bypass for hypoglycemia. (23666968)
2013
9
Diagnosis of septo-optic dysplasia in a neonate with hypernatremia, hypoglycemia, and persistent hypothermia. (23813351)
2013
10
A randomized trial comparing the rate of hypoglycemia--assessed using continuous glucose monitoring--in 125 preschool children with type 1 diabetes treated with insulin glargine or NPH insulin (the PRESCHOOL study). (23730996)
2013
11
Hypoglycemia in patients with type 1 diabetes: epidemiology, pathogenesis, and prevention. (23912765)
2013
12
Central pontine myelinolysis following acute hypoglycemia. (23948485)
2013
13
Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha and 4 alpha in maturity-onset diabetes of the young and hyperinsulinemic hypoglycemia. (23348805)
2013
14
The effect of adjusting for baseline hypoglycemia when analyzing hypoglycemia data: a systematic analysis of 15 diabetes clinical trials. (23883405)
2013
15
Prevention of hypoglycemia-induced neuronal death by minocycline. (22998689)
2012
16
Peripubertal hypoglycemia--an unusual cause. (22570977)
2012
17
The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction. (22363801)
2012
18
Prediction and prevention of treatment-related inpatient hypoglycemia. (22538139)
2012
19
Continuous glucose monitoring after islet transplantation in type 1 diabetes: an excellent graft function (I^-score greater than 7) Is required to abrogate hyperglycemia, whereas a minimal function is necessary to suppress severe hypoglycemia (I^-score greater than 3). (22996144)
2012
20
Hypoglycemia is associated with increased risk for brain injury and adverse neurodevelopmental outcome in neonates at risk for encephalopathy. (22306045)
2012
21
Identification of hypoglycemia and hyperglycemia in type 1 diabetic patients using ECG parameters. (23366486)
2012
22
Novel compound heterozygous mutations in the fructose-1,6-bisphosphatase gene cause hypoglycemia and lactic acidosis. (20096900)
2011
23
Hypoglycemia detection based on cardiac repolarization features. (22255386)
2011
24
Retroperitoneal solitary fibrous tumor-induced hypoglycemia associated with high molecular weight insulin-like growth factor II. (20852090)
2010
25
The insertion/deletion polymorphism in the angiotensin-converting enzyme gene and hypoglycemia awareness in patients with type 1 diabetes. (16981144)
2006
26
Hyperinsulinemic hypoglycemia due to adult nesidioblastosis in insulin-dependent diabetes. (17131493)
2006
27
Recent advances in hyperinsulinemic hypoglycemia of infancy. (16982483)
2006
28
Growth restriction and exendin 4 promote endocrine expression in cultured islet cells derived from patients with persistent hyperinsulinemic hypoglycemia of infancy (PHHI). (16353670)
2005
29
A rapid method for analyzing serum pro-insulin-like growth factor-II in patients with non-islet cell tumor hypoglycemia. (15840753)
2005
30
Insulin-induced hypoglycemia suppresses plasma parathyroid hormone levels in patients with adrenal insufficiency. (15375778)
2004
31
A young woman with persistent hypoglycemia, rhabdomyolysis, and coma: recognizing fatty acid oxidation defects in adults. (12682504)
2003
32
Transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia. (11444360)
2001
33
Hemangiopericytoma of the seminal vesicle presenting with hypoglycemia. (11490268)
2001
34
Hormonal and metabolic counterregulation during and after high-dose insulin-induced hypoglycemia in diabetes mellitus type 2. (11069207)
2000
35
Effect of DW2282 on the induction of methemoglobinemia, hypoglycemia or WBC count and hematological changes. (10615861)
1999
36
Pancreatic alpha-cell function in idiopathic reactive hypoglycemia. (9186298)
1997
37
The use of tolbutamide-induced hypoglycemia to examine the intraislet role of insulin in mediating glucagon release in normal humans. (9141533)
1997
38
Insulin-associated modulation of neuroendocrine counterregulation, hypoglycemia perception, and cerebral function in insulin-dependent diabetes mellitus: evidence for an intrinsic effect of insulin on the central nervous system. (8772600)
1996
39
Insulin-like growth factor II expression in primary meningeal hemangiopericytoma and its metastasis to the liver accompanied by hypoglycemia. (8760024)
1996
40
Octreotide reverses hyperinsulinemia and prevents hypoglycemia induced by sulfonylurea overdoses. (8445035)
1993
41
Effects of insulin on the counterregulatory response to equivalent hypoglycemia in normal females. (8238493)
1993
42
Hypoglycemia associated hospitalizations in a population with a high prevalence of non-insulin-dependent diabetes mellitus. (1756685)
1991
43
Symptoms of hypoglycemia--a comparison between porcine and human insulin. (2192194)
1990
44
Nesidioblastosis and intermediate cells in the pancreas of patients with hyperinsulinemic hypoglycemia. (2858937)
1985
45
Factitious hypoglycemia associated with eosinophilic leukemoid reaction. (3856121)
1985
46
Hyperinsulinemic hypoglycemia. Differential diagnosis by determination of the species of circulating insulin. (6387203)
1984
47
Impaired pancreatic polypeptide responses to insulin-induced hypoglycemia in diabetic autonomic neuropathy. (6987250)
1980
48
Omphalocoele, macroglossia and neonatal hypoglycemia (Beckwith's syndrome): two cases of Kenyan newborns. (4779525)
1973
49
Hypoglycemia associated with serous cystadenocarcinoma of the ovary. (4189963)
1970
50
Picture of the month: syndrome of neonatal hypoglycemia, macroglossia, visceromegaly, and omphalocele. (5640529)
1968

Genetic Variations for Hypoglycemia

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Expression for genes affiliated with Hypoglycemia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypoglycemia

Search GEO for disease gene expression data for Hypoglycemia.

Pathways for genes affiliated with Hypoglycemia

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Sources:
53Reactome, 29KEGG, 37NCBI BioSystems Database, 12EMD Millipore, 49PharmGKB, 51QIAGEN, 4Cell Signaling Technology
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Pathways related to Hypoglycemia according to GeneCards/GeneDecks:

(show all 27)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.9KCNJ11, GCG, GCK, PYGL, HADH, G6PC
210.9ACADM, KCNJ11, GCK, HNF4A, HADH, G6PC
3
Translation Insulin regulation of translation
Hide members
10.8GCK, PYGL, G6PC, FBP1, GYS2, INS
4
Hide members
10.8KCNJ11, GCK, HNF4A, INS, INSR, ABCC8
5
Hide members
10.8INS, ABCC8, SLC25A20, SLC16A1, ACADM, ACADL
6
Hide members
10.7GCK, PYGL, G6PC, FBP1, GYS2
710.7KCNJ11, GCG, GCK, INS, ABCC8
8
Hide members
10.7SLC16A1, SLC22A5, ABCC8, G6PC, GCK
9
Hide members
10.7INSR, IGF2, GYS2, PYGL, GCG
1010.7GCG, HNF4A, GLUD1, INS, INSR
11
Hide members
10.7ACADL, ACADM, SLC25A20, HADH
12
Hide members
10.7HADH, SLC25A20, ACADM, ACADL
13
Hide members
10.7GCK, PYGL, G6PC, GYS2
14
Galactose metabolism
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10.7GCK, PYGL, G6PC, GYS2
15
Hide members
10.7KCNJ11, GCG, INS, ABCC8
16
Hide members
10.7INSR, INS, HNF4A, GCK
17
Development Leptin signaling via PI3K-dependent pathway
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10.6ABCC8, GYS2, KCNJ11
18
Hide members
10.6GCK, G6PC, FBP1
19
Hide members
10.6GYS2, FBP1, PYGL
20
Hide members
10.6INS, HNF4A, GCK
2110.6HNF4A, GYS2, INSR
22
Hide members
10.6INSR, INS, IGF2
23
Hide members
10.6IGF2, INS, INSR
2410.6ABCC8, KCNJ11
25
Hide members
10.6HADH, ACADM
2610.6GCG, CRH
27
Hide members
10.6INS, INSR

Compounds for genes affiliated with Hypoglycemia

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Sources:
44Novoseek, 24HMDB, 11DrugBank, 59Tocris Bioscience, 28IUPHAR, 49PharmGKB, 2BitterDB
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Compounds related to Hypoglycemia according to GeneCards/GeneDecks:

(show top 50)    (show all 126)
idCompoundScoreTop Affiliating Genes
1glucose4411.8KCNJ11, GCG, GCK, HNF4A, PYGL, HADH
2glutamate4411.6CRH, IGF2, GLUD1, INS, INSR, ABCC8
3arginine4411.6SLC22A5, KCNJ11, GCG, GCK, G6PC, CRH
4fatty acid4411.4GCG, GCK, HNF4A, GLUD1, ABCC8, SLC25A20
5glycogen44 2412.4G6PC, IGF2, ABCC8, INSR, INS, HNF4A
6glutamine4411.4GCG, G6PC, IGF2, GLUD1, INSR, KCNJ11
7lipid4411.3SLC25A20, ABCC8, INS, GCG, ACADM, ACADL
8carnitine4411.3IGF2, GLUD1, ACADL, ACADM, SLC22A5, SLC25A20
9glycerol44 11 2413.3GCG, HNF4A, CRH, GLUD1, INS, INSR
10alanine4411.3GCK, HNF4A, GCG, INS, GLUD1, IGF2
11katp4411.3KCNJ11, GCK, GCG, GLUD1, HADH, INS
12lactate4411.3IGF2, INS, SLC16A1, ACADM, GLUD1, G6PC
13creatinine4411.3CRH, IGF2, GLUD1, GCG, INSR, INS
14c-peptide4411.3IGF2, KCNJ11, GCG, GCK, HNF4A, INS
15diazoxide44 59 28 1114.2INS, GLUD1, HADH, ABCC8, KCNJ11, GCK
16sulfonylurea4411.2GCK, ABCC8, GLUD1, GCG, INS, KCNJ11
17tolbutamide44 49 28 1114.2ABCC8, GLUD1, GCK, GCG, KCNJ11, INS
18dexamethasone44 49 28 1114.2GCK, HNF4A, CRH, G6PC, INSR, GLUD1
19glibenclamide44 28 49 5914.2KCNJ11, GCG, ABCC8, INSR, INS, CRH
20metformin44 49 1113.2GCK, INS, INSR, ABCC8, KCNJ11, GCG
212-deoxyglucose44 1112.2GCG, IGF2, GCK, G6PC, INSR, INS
22acyl-coa4411.2HADH, HNF4A, ACADL, ACADM, SLC25A20, GLUD1
23glimepiride44 49 1113.2ABCC8, INSR, INS, GCG, KCNJ11
24leucine4411.1HNF4A, GCK, HADH, G6PC, GLUD1, ABCC8
25streptozotocin4411.1GCK, INSR, GCG, INS, G6PC
26octreotide44 59 28 1114.1GCG, CRH, IGF2, INSR, INS
27repaglinide44 49 1113.1GCG, INS, KCNJ11, ABCC8
28beta-hydroxybutyrate4411.1GLUD1, INS, SLC16A1, G6PC
29gliclazide44 49 1113.1KCNJ11, INS, INSR, ABCC8
30rapamycin4411.1GCG, IGF2, INS, INSR, GLUD1, G6PC
31verapamil44 49 28 11 2415.0SLC22A5, KCNJ11, IGF2, INSR, CRH
32nateglinide44 49 1113.0ABCC8, INS, GCG, SLC16A1
33cysteine4411.0GLUD1, ABCC8, GCG, IGF2, CRH, HNF4A
34glucose 6-phosphate44 2412.0GCK, GLUD1, PYGL, G6PC
35meglitinide4411.0INS, ABCC8, GCG
36aicar44 11 2413.0INS, INSR, GCK, G6PC
37chromium picolinate4411.0INS, INSR, GCK
38palmitate4410.9HNF4A, INS, ACADM
39phosphoenolpyruvate44 1111.9G6PC, GCK, HNF4A, GLUD1
40preproinsulin4410.9INSR, INS, GCK
41moxonidine4410.9SLC22A5, INSR, INS
42i-app4410.9GCG, GCK, INS
43pyruvate4410.8GCK, G6PC, HNF4A, SLC16A1, GLUD1
44fructose-6-phosphate44 1111.8FBP1, G6PC, GCK
45incretin4410.8GCG, GCK, INS
46dhea4410.7G6PC, CRH, IGF2, INS
47epinephrine44 11 2412.7INSR, CRH, SLC22A5, GCG, INS
48pioglitazone44 49 28 1113.7INS, INSR, IGF2, GCG
49serine4410.6CRH, IGF2, GCG, GLUD1, INS, INSR
50chloramphenicol44 2 1112.6HNF4A, CRH, IGF2, INSR, ACADM

GO Terms for genes affiliated with Hypoglycemia

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Sources:
16Gene Ontology
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Cellular components related to Hypoglycemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrionGO:00573910.8ACADL, KCNJ11, GCK, HADH, GLUD1, SLC25A20
2secretory granule lumenGO:03477410.6INS, GCG
3mitochondrial matrixGO:00575910.4ACADL, ACADM, GLUD1, HADH

Biological processes related to Hypoglycemia according to GeneCards/GeneDecks:

(show all 27)
idNameGO IDScoreTop Affiliating Genes
1small molecule metabolic processGO:04428111.6ACADL, KCNJ11, GCG, GCK, PYGL, HADH
2carbohydrate metabolic processGO:00597511.2GCK, PYGL, G6PC, FBP1, GYS2, INSR
3regulation of insulin secretionGO:05079611.2KCNJ11, GCG, GCK, HNF4A, INS, ABCC8
4glucose homeostasisGO:04259311.1GCK, HNF4A, PYGL, G6PC, INS, INSR
5glucose metabolic processGO:00600611.1KCNJ11, PYGL, FBP1, GYS2, IGF2, INS
6positive regulation of glycogen biosynthetic processGO:04572511.0GCK, IGF2, INS, INSR
7energy reserve metabolic processGO:00611211.0KCNJ11, GCG, INS, ABCC8
8glycogen biosynthetic processGO:00597811.0ACADM, GYS2, GCK
9positive regulation of glycolysisGO:04582111.0GCK, INS, INSR
10cellular lipid metabolic processGO:04425511.0ACADL, ACADM, SLC25A20, HADH
11fatty acid beta-oxidationGO:00663510.9HADH, ACADM, ACADL
12positive regulation of mitosisGO:04584010.9INSR, INS, IGF2
13endocrine pancreas developmentGO:03101810.9GCK, HNF4A, INS
14positive regulation of respiratory burstGO:06026710.9INS, INSR
15carnitine metabolic process, CoA-linkedGO:01925410.9ACADM, ACADL
16glucose transportGO:01575810.9GCK, G6PC, INS
17fatty acid beta-oxidation using acyl-CoA dehydrogenaseGO:03353910.8ACADM, ACADL
18negative regulation of epinephrine secretionGO:03281110.8GCK, CRH
19positive regulation of MAPK cascadeGO:04341010.8INSR, INS, IGF2
20positive regulation of protein kinase B signaling cascadeGO:05189710.8IGF2, INS, INSR
21positive regulation of insulin receptor signaling pathwayGO:04662810.8INS, IGF2
22negative regulation of gluconeogenesisGO:04572110.7INS, GCK
23positive regulation of calcium ion importGO:09028010.6GCG, CRH
24transmembrane transportGO:05508510.6GCK, G6PC, ABCC8, SLC22A5, SLC16A1
25regulation of gluconeogenesisGO:00611110.6FBP1, ACADM
26positive regulation of insulin secretion involved in cellular response to glucose stimulusGO:03577410.6CRH, GCG
27positive regulation of protein phosphorylationGO:00193410.3INSR, IGF2, CRH

Molecular functions related to Hypoglycemia according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00517910.8GCG, CRH, IGF2, INS
2insulin-like growth factor receptor bindingGO:00515910.8INSR, INS, IGF2
3identical protein bindingGO:04280210.8GCG, FBP1, GLUD1, INS, ACADM
4glucose bindingGO:00553610.7PYGL, GCK
5AMP bindingGO:01620810.6FBP1, PYGL
6NAD+ bindingGO:07040310.6GLUD1, HADH
7ATP bindingGO:00552410.5KCNJ11, GCK, PYGL, GLUD1, INSR, ABCC8
8acyl-CoA dehydrogenase activityGO:00399510.5ACADL, ACADM

Products for genes affiliated with Hypoglycemia

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  • Antibodies
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Sources for Hypoglycemia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet