MCID: HYP064
MIFTS: 37

Hypogonadotropism malady

Categories: Endocrine diseases

Aliases & Classifications for Hypogonadotropism

Aliases & Descriptions for Hypogonadotropism:

Name: Hypogonadotropism 12 52 14
Hypogonadism 69

Classifications:



External Ids:

Disease Ontology 12 DOID:7455

Summaries for Hypogonadotropism

MalaCards based summary : Hypogonadotropism, also known as hypogonadism, is related to hypogonadotropic hypogonadism 7 without anosmia and hypogonadotropic hypogonadism 12 with or without anosmia. An important gene associated with Hypogonadotropism is RNF216 (Ring Finger Protein 216), and among its related pathways/superpathways is Peptide ligand-binding receptors. The drugs Testosterone and Dihydrotachysterol have been mentioned in the context of this disorder. Affiliated tissues include bone, pituitary and testes, and related phenotypes are integument and liver/biliary system

Related Diseases for Hypogonadotropism

Diseases related to Hypogonadotropism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
id Related Disease Score Top Affiliating Genes
1 hypogonadotropic hypogonadism 7 without anosmia 12.1
2 hypogonadotropic hypogonadism 12 with or without anosmia 12.1
3 hypogonadotropic hypogonadism 2 with or without anosmia 12.1
4 hypogonadotropic hypogonadism 13 with or without anosmia 12.1
5 hypogonadotropic hypogonadism 15 with or without anosmia 12.1
6 hypogonadotropic hypogonadism 11 with or without anosmia 12.1
7 hypogonadotropic hypogonadism 16 with or without anosmia 12.1
8 hypogonadotropic hypogonadism with or without anosmia 12.1
9 hypogonadotropic hypogonadism 10 with or without anosmia 12.1
10 hypogonadotropic hypogonadism 1 with or without anosmia 12.1
11 hypogonadotropic hypogonadism 18 with or without anosmia 12.1
12 hypogonadotropic hypogonadism 20 with or without anosmia 12.1
13 hypogonadotropic hypogonadism 9 with or without anosmia 12.1
14 hypogonadotropic hypogonadism 14 with or without anosmia 12.1
15 hypogonadotropic hypogonadism 8 with or without anosmia 12.1
16 hypogonadotropic hypogonadism 4 with or without anosmia 12.1
17 hypogonadotropic hypogonadism 17 with or without anosmia 12.1
18 hypogonadotropic hypogonadism 6 with or without anosmia 12.1
19 hypogonadotropic hypogonadism 19 with or without anosmia 12.1
20 hypogonadotropic hypogonadism 3 with or without anosmia 12.1
21 hypogonadotropic hypogonadism 21 with anosmia 12.1
22 cerebellar ataxia and hypogonadotropic hypogonadism 12.1
23 leukodystrophy, hypomyelinating, 8, with or without oligodontia and/or hypogonadotropic hypogonadism 12.1
24 hypogonadotropic hypogonadism 5 with or without anosmia 12.0
25 leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism 12.0
26 hypogonadotropic hypogonadism 23 with or without anosmia 12.0
27 hypogonadotropic hypogonadism 24 without anosmia 11.9
28 adrenal hypoplasia, congenital, with hypogonadotropic hypogonadism 11.9
29 normosmic congenital hypogonadotropic hypogonadism 11.8
30 kallmann syndrome 11.8
31 hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome 11.6
32 multicore myopathy with mental retardation, short stature, and hypogonadotropic hypogonadism 11.6
33 hypogonadotropic hypogonadism without anosmia, x-linked 11.6
34 hypogonadotropic hypogonadism-frontoparietal alopecia syndrome 11.6
35 hypogonadotropic hypogonadism-retinitis pigmentosa syndrome 11.6
36 moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome 11.6
37 boucher-neuhauser syndrome 11.5
38 arhinia, choanal atresia, and microphthalmia 11.3
39 klinefelter's syndrome 11.2
40 hemochromatosis 11.1
41 x-linked adrenal hypoplasia congenita 11.0
42 isolated gonadotropin-releasing hormone deficiency 11.0
43 pol iii-related leukodystrophies 11.0
44 ataxia - hypogonadism - choroidal dystrophy 10.9
45 hypogonadism 10.9
46 leukodystrophy, hypomyelinating, 11 10.8
47 oliver-mcfarlane syndrome 10.8
48 waardenburg syndrome, type 2e, with or without neurologic involvement 10.7
49 hs6st1-related isolated gonadotropin-releasing hormone deficiency 10.7
50 kiss1-related isolated gonadotropin-releasing hormone deficiency 10.7

Graphical network of the top 20 diseases related to Hypogonadotropism:



Diseases related to Hypogonadotropism

Symptoms & Phenotypes for Hypogonadotropism

MGI Mouse Phenotypes related to Hypogonadotropism:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.46 GNRH1 KISS1 KISS1R PRL
2 liver/biliary system MP:0005370 9.26 KISS1 KISS1R PRL GNRH1
3 reproductive system MP:0005389 9.02 GNRH1 KISS1 KISS1R PRL RNF216

Drugs & Therapeutics for Hypogonadotropism

Drugs for Hypogonadotropism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 197)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-22-0 6013
2
Dihydrotachysterol Approved Phase 4,Phase 2,Phase 1 67-96-9 5281010 5311071
3
Methyltestosterone Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-18-4 6010
4
Zinc Approved Phase 4,Phase 3,Phase 1,Phase 2 7440-66-6 32051 23994
5
Progesterone Approved, Vet_approved Phase 4,Phase 3 57-83-0 5994
6
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Early Phase 1 50-28-2 5757 53477783
7
Metformin Approved Phase 4,Phase 3,Phase 2 657-24-9 14219 4091
8
Dutasteride Approved, Investigational Phase 4,Phase 2,Phase 1 164656-23-9 152945 6918296
9
Anastrozole Approved, Investigational Phase 4,Phase 2,Phase 1,Early Phase 1 120511-73-1 2187
10
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
11
Menotropins Approved Phase 4 61489-71-2 5360545
12
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 3 67-97-0 6221 10883523 5280795
13
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3 50-14-6 5280793
14
decanoic acid Experimental Phase 4 334-48-5 2969
15
N,N-dimethylarginine Experimental Phase 4 30315-93-6 123831
16 Testosterone undecanoate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
17 Chorionic Gonadotropin Phase 4,Phase 3
18 Follicle Stimulating Hormone Phase 4,Phase 3,Phase 2
19 Testosterone 17 beta-cypionate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
20
Testosterone enanthate Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 315-37-7 9416
21 Anabolic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
22 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
23 Androgens Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
24 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
25 Vardenafil Dihydrochloride Phase 4
26 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 Vasodilator Agents Phase 4,Early Phase 1
28 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
29 Phosphodiesterase 5 Inhibitors Phase 4,Phase 3,Phase 2,Early Phase 1
30 Phosphodiesterase Inhibitors Phase 4,Phase 3,Phase 2,Early Phase 1
31 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
32 Central Nervous System Depressants Phase 4,Phase 1,Phase 2
33 vitamin d Phase 4,Phase 3,Phase 2
34 insulin Phase 4,Phase 3,Phase 2,Phase 1
35 Estradiol valerate Phase 4,Phase 3,Early Phase 1 979-32-8
36 Triptorelin Pamoate Phase 4
37 Mitogens Phase 4
38 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
39 Contraceptive Agents Phase 4,Phase 3,Phase 2,Early Phase 1
40 Trace Elements Phase 4,Phase 3,Phase 2
41 Tranquilizing Agents Phase 4
42 Estradiol 17 beta-cypionate Phase 4,Phase 3,Early Phase 1
43 Hypoglycemic Agents Phase 4,Phase 3,Phase 2,Phase 1
44 Estradiol 3-benzoate Phase 4,Phase 3,Early Phase 1
45 Estrogen Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
46 Vitamins Phase 4,Phase 3,Phase 2
47 Estrogens Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
48 Polyestradiol phosphate Phase 4,Phase 3,Early Phase 1
49 5-alpha Reductase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
50 Fenugreek seed meal Phase 4

Interventional clinical trials:

(show top 50) (show all 321)
id Name Status NCT ID Phase
1 Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism Unknown status NCT02310074 Phase 4
2 Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism Unknown status NCT01084369 Phase 4
3 Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism Unknown status NCT02140515 Phase 4
4 Effect of Androgel on Type 2 Diabetic Males With Hypogonadism Unknown status NCT00350701 Phase 4
5 Odense Androgen Study - The Effect of Testim and Training in Hypogonadal Men Unknown status NCT00700024 Phase 4
6 Open-label, Follow-up Study of Oral Testosterone Undecanoate in Hypogonadal Men Unknown status NCT01699178 Phase 4
7 Testosterone Replacement in Older Men and Atherosclerosis Progression Unknown status NCT00287586 Phase 4
8 Testosterone for Peripheral Vascular Disease Unknown status NCT00504712 Phase 4
9 Effects of Medications in Patients With Hypogonadism Completed NCT01601327 Phase 4
10 Testosterone Replacement Therapy Decreases Plasma Paraoxonase 1 Enzyme Activity In Male Patients With Hypogonadism Completed NCT01107067 Phase 4
11 Metabolic Syndrome Criteria and the Effect of Testosterone Treatment in Young Men With Hypogonadism Completed NCT01160341 Phase 4
12 Endothelial Dysfunction, Inflammation and Insulin Resistance in Congenital Hypogonadism and Effect of Testosteron Replacement Therapy Completed NCT02171390 Phase 4
13 Sequential Therapy for Hypogonadotropic Hypogonadism Completed NCT01403532 Phase 4
14 Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism and Effect of Testosteron Treatment Completed NCT02111434 Phase 4
15 The Effect of Testosterone Replacement on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Hypogonadotrophic Hypogonadism Completed NCT01533129 Phase 4
16 The Effect of Testosteron Replacement Treatment on the Fibroblast Growth Factor-23, Asymmetric Dimethylarginine and Vitamin D Levels in the Congenital Hypogonadotropic Hypogonadism Completed NCT02111473 Phase 4
17 The Effect of Testosterone Replacement on the High Density Lipoprotein Cholesterol Subgroups Completed NCT01454011 Phase 4
18 Effects of Testosterone on Myocardial Repolarization Completed NCT03126656 Phase 4
19 Testosterone Replacement in Men With Diabetes and Obesity Completed NCT01127659 Phase 4
20 MRI Substudy; Metabolic Changes Due to Iatrogenic Hypogonadism Completed NCT02102646 Phase 4
21 ESPRIT Study in Hypogonadal Men Completed NCT01143818 Phase 4
22 The Therapy of Nebido as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction Completed NCT00421460 Phase 4
23 TRADE-Testosterone Replacement and Dutasteride Effectiveness Completed NCT00194675 Phase 4
24 Efficacy of Fenugreek Seed and Lespedeza Cuneata in TDS Completed NCT03057899 Phase 4
25 The Effect of Testosterone Topical Solution (LY900011) in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel Completed NCT01893281 Phase 4
26 Efficacy Study for Use of Dutasteride (Avodart) With Testosterone Replacement Completed NCT00752869 Phase 4
27 Effect of Testosterone Replacement on Insulin Resistance Completed NCT00487734 Phase 4
28 Testosterone Replacement in Diabetes With Vascular Disease (Version 2) Completed NCT00355537 Phase 4
29 Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism Completed NCT00837616 Phase 4
30 Testosterone for Men With Insulin Treated Type 2 Diabetes Completed NCT00349362 Phase 4
31 Testosterone Replacement in Metabolic Syndrome and Inflammation Completed NCT01123278 Phase 4
32 Testosterone Therapy of Men With Type 2 Diabetes Mellitus (T2DM) Completed NCT01560546 Phase 4
33 Aripiprazole and Prolactin Study Completed NCT01085383 Phase 4
34 Severe LH Suppressed Patients After Administration of a GnRH Antagonist Completed NCT01936077 Phase 4
35 FSH/LH Ratio as a Predictor of IVF Outcome in Young and Older Women Completed NCT02674178 Phase 4
36 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4
37 Open-Label Study, Evaluating Patient Satisfaction and Symptom Improvement When Treating Male Hypogonadism With Natesto™ Recruiting NCT02937740 Phase 4
38 Human Menopausal Gonadotropin Combining With Human Chorionic Gonadotropin Treat Congenital Hypogonadotropic Hypogonadism Recruiting NCT02880280 Phase 4
39 Vitamin D Treatment and Hypogonadism in Men Recruiting NCT01748370 Phase 4
40 Testosterone Therapy in Hypogonadal Men Treated With Opioids Recruiting NCT02433730 Phase 4
41 Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot) Recruiting NCT02959853 Phase 4
42 Subcutaneous vs. Intramuscular Testosterone Recruiting NCT03091348 Phase 4
43 Periodontal Profile of Hypogonadic Men Recruiting NCT03176537 Phase 4
44 Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment Recruiting NCT02408445 Phase 4
45 TRT on BPH Hypoganadal MetS Patients. Florence-PROTEST Active, not recruiting NCT02366975 Phase 4
46 The Health Influences of Puberty (HIP) Study Active, not recruiting NCT01775813 Phase 4
47 NEBIDO in Symptomatic Late Onset Hypogonadism (SLOH) Terminated NCT01092858 Phase 4
48 Luveris® (Lutropin Alfa for Injection) in Women With Hypogonadotropic Hypogonadism (Luteinizing Hormone [LH] Less Than [<] 1.2 International Unit Per Liter [IU/L]) Terminated NCT00328926 Phase 4
49 TOM: Testosterone in Older Men With Sarcopenia Terminated NCT00240981 Phase 4
50 Nebido Versus Placebo in Elderly Men With Typical Symptoms of Late Onset Hypogonadism Over a Period of 54 Weeks Withdrawn NCT00710827 Phase 4

Search NIH Clinical Center for Hypogonadotropism

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Hypogonadotropism

Anatomical Context for Hypogonadotropism

MalaCards organs/tissues related to Hypogonadotropism:

39
Bone, Pituitary, Testes, Eye, Prostate, Ovary, Testis

Publications for Hypogonadotropism

Articles related to Hypogonadotropism:

(show top 50) (show all 382)
id Title Authors Year
1
Boucher NeuhAouser Syndrome - A rare cause of inherited hypogonadotropic hypogonadism. A case of two adult siblings with two novel mutations in PNPLA6. ( 27866050 )
2017
2
Congenital hypogonadotropic hypogonadism, functional hypogonadotropism or constitutional delay of growth and puberty? An analysis of a large patient series from a single tertiary center. ( 27927844 )
2017
3
FGFR1 Analyses in Four Patients with Hypogonadotropic Hypogonadism with Split-Hand/Foot Malformation: Implications for the Promoter Region. ( 28087897 )
2017
4
Hypogonadotropic hypogonadism in a female patient with congenital arhinia. ( 27941181 )
2017
5
Anti-MA1llerian Hormone and Ovarian Morphology in Women With Isolated Hypogonadotropic Hypogonadism/Kallmann Syndrome: Effects of Recombinant Human FSH. ( 28324034 )
2017
6
Comparison of bone mineral density in adolescent girls with the diagnosis of hypogonadotropic hypogonadism and hypergonadotropic hypogonadism. ( 27087454 )
2016
7
Reproductive endocrinology: New treatment protocol for hypogonadotropic hypogonadism. ( 27516343 )
2016
8
Kisspeptin levels in idiopathic hypogonadotropic hypogonadism diagnosed male patients and its relation with glucose-insulin dynamic. ( 27616469 )
2016
9
Expanding the CHARGE Geno-Phenotype: A Girl with Novel CHD7 Deletion, Hypogonadotropic Hypogonadism, and Agenesis of Uterus and Ovaries. ( 26741373 )
2016
10
Congenital hypogonadotropic hypogonadism: implications of absent mini-puberty. ( 27213784 )
2016
11
Neuroradiological findings in hypogonadotropic hypogonadism. ( 27050382 )
2016
12
Complete Idiopathic Hypogonadotropic Hypogonadism due to Homozygous GNRH1 Mutations in the Mutational Hot Spots in the Region Encoding the Decapeptide. ( 26595427 )
2016
13
Reversal of congenital hypogonadotropic hypogonadism in a man with Kallmann syndrome due to SOX10 mutation. ( 27616149 )
2016
14
X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism: Identification and inA vitro study of a novel small indel in the NR0B1 gene. ( 27035099 )
2016
15
Hypogonadotropic hypogonadism and metabolic syndrome: insights from the high-fat diet experimental rabbit animal model. ( 27050381 )
2016
16
CCDC141 Mutation Identified in Anosmic Hypogonadotropic Hypogonadism (Kallmann Syndrome) Alters GnRH Neuronal Migration. ( 27014940 )
2016
17
A successful healthy live birth from a female patient with hypogonadotropic hypogonadism and oocytes with unusually large cytoplasmic inclusions. ( 27203307 )
2016
18
Evaluation of Basal Serum Adrenocorticotropic Hormone and Cortisol Levels and Their Relationship with Nonalcoholic Fatty Liver Disease in Male Patients with Idiopathic Hypogonadotropic Hypogonadism. ( 27174321 )
2016
19
Adherence to treatment in men with hypogonadotropic hypogonadism. ( 27647266 )
2016
20
Hypogonadotropic Hypogonadism and Short Stature in Patients with Diabetes due to Neurogenin 3 Deficiency. ( 27533310 )
2016
21
Circulating makorin ring-finger protein-3 (MKRN3) levels in healthy men and in men with hypogonadotropic hypogonadism. ( 26175221 )
2016
22
Idiopathic Hypogonadotropic Hypogonadism Caused by Inactivating Mutations in SRA1. ( 27086651 )
2016
23
Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome. ( 27502037 )
2016
24
Phenotypic spectrum of POLR3B mutations: isolated hypogonadotropic hypogonadism without neurological or dental anomalies. ( 27512013 )
2016
25
Pulsatile gonadotropin-releasing hormone therapy is associated with earlier spermatogenesis compared to combined gonadotropin therapy in patients with congenital hypogonadotropic hypogonadism. ( 28051040 )
2016
26
Clinical, endocrinological, and molecular characterization of Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism: a single center experience. ( 25883924 )
2015
27
Hypogonadotropic Hypogonadism in Infants with Congenital Hypopituitarism: A Challenge to Diagnose at an Early Stage. ( 26355950 )
2015
28
Comment on reversal of hypogonadotropic hypogonadism in a Chinese cohort. ( 25814161 )
2015
29
Triallelic digenic mutation in the prokineticin 2 and GNRH receptor genes in two brothers with normosmic congenital hypogonadotropic hypogonadism. ( 25531638 )
2015
30
Mutations in KISS1 are not responsible for idiopathic hypogonadotropic hypogonadism in Chinese patients. ( 25783047 )
2015
31
Psychosexual development in men with congenital hypogonadotropic hypogonadism on long-term treatment: a mixed methods study. ( 25844173 )
2015
32
Congenital Hypogonadotropic Hypogonadism and Kallmann Syndrome: Past, Present, and Future. ( 26790381 )
2015
33
Adrenal Hypoplasia Congenita: A Rare Cause of Primary Adrenal Insufficiency and Hypogonadotropic Hypogonadism. ( 26500747 )
2015
34
The Effects of Gonadotropin Replacement Therapy on Metabolic Parameters and Body Composition in Men with Idiopathic Hypogonadotropic Hypogonadism. ( 26485362 )
2015
35
Sequential versus Continual Purified Urinary FSH / hCG in Men with Idiopathic Hypogonadotropic Hypogonadism. ( 25825944 )
2015
36
Changes in Bone Mineral Density and Metabolic Parameters after Pulsatile Gonadorelin Treatment in Young Men with Hypogonadotropic Hypogonadism. ( 26417369 )
2015
37
Hypogonadotropic hypogonadism in a trisomy X carrier: phenotype description and genotype correlation. ( 26572316 )
2015
38
Effects of androgen replacement therapy on cornea and tear function in men with idiopathic hypogonadotropic hypogonadism. ( 25812631 )
2015
39
Congenital combined pituitary hormone deficiency patients have better responses to gonadotrophin-induced spermatogenesis than idiopathic hypogonadotropic hypogonadism patients. ( 26141714 )
2015
40
Normosmic idiopathic hypogonadotropic hypogonadism due to a novel homozygous nonsense c.C969A (p.Y323X) mutation in the KISS1R gene in three unrelated families. ( 25262569 )
2015
41
Novel FGFR1 mutations in Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism: evidence for the involvement of an alternatively spliced isoform. ( 26277103 )
2015
42
A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism. ( 26266058 )
2015
43
Pregnancy outcome of assisted reproductive technology cycle in patients with hypogonadotropic hypogonadism. ( 26538857 )
2015
44
Novel mutations of DAX1 (NR0B1) in two Chinese families with X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. ( 25968435 )
2015
45
Mutation screening of SEMA3A and SEMA7A in patients with congenital hypogonadotropic hypogonadism. ( 24522099 )
2014
46
Restoration of fertility by gonadotropin replacement in a man with hypogonadotropic azoospermia and testicular adrenal rest tumours due to untreated simple virilising congenital adrenal hyperplasia. ( 24394723 )
2014
47
Effect of androgen replacement therapy on atherosclerotic risk markers in young-to-middle-aged men with idiopathic hypogonadotropic hypogonadism. ( 25280063 )
2014
48
Cost-effectiveness analysis on the use of rFSH + rLH for the treatment of anovulation in hypogonadotropic hypogonadal women. ( 25028553 )
2014
49
Boucher-NeuhAouser syndrome: cerebellar degeneration, chorioretinal dystrophy and hypogonadotropic hypogonadism: two novel cases and a review of 40 cases from the literature. ( 25359264 )
2014
50
A tunisian patient with two rare syndromes: triple a syndrome and congenital hypogonadotropic hypogonadism. ( 25247238 )
2014

Variations for Hypogonadotropism

Expression for Hypogonadotropism

Search GEO for disease gene expression data for Hypogonadotropism.

Pathways for Hypogonadotropism

GO Terms for Hypogonadotropism

Biological processes related to Hypogonadotropism according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to organic cyclic compound GO:0014070 9.26 GNRH1 PRL
2 response to ethanol GO:0045471 9.16 GNRH1 PRL
3 female pregnancy GO:0007565 8.96 GNRH1 PRL
4 ovulation cycle GO:0042698 8.62 GNRH1 PRL

Molecular functions related to Hypogonadotropism according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 GNRH1 PRL

Sources for Hypogonadotropism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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