Aliases & Classifications for Hypohidrosis

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Aliases & Descriptions for Hypohidrosis:

Name: Hypohidrosis 10 47 12 36 65
 
Oligohidrosis 10

Classifications:



External Ids:

Disease Ontology10 DOID:11155
ICD1027 L74.4
SNOMED-CT59 201189007, 45004005
MeSH36 D007007
NCIt42 C34718
UMLS65 C0020620

Summaries for Hypohidrosis

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Wikipedia:68 Hypohidrosis is diminished sweating in response to appropriate stimuli. While hyperhidrosis is a... more...

MalaCards based summary: Hypohidrosis, also known as oligohidrosis, is related to ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant and ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant, and has symptoms including unmasking of previously unidentified disease, autoresuscitation and fat tissue decreased. An important gene associated with Hypohidrosis is COG6 (Component Of Oligomeric Golgi Complex 6), and among its related pathways is TNF Signaling (sino). Affiliated tissues include skin, b cells and myeloid, and related mouse phenotypes are pigmentation and respiratory system.

Related Diseases for Hypohidrosis

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Diseases related to Hypohidrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant30.2EDAR, EDARADD
2ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant30.2EDAR, EDARADD
3hypohidrotic ectodermal dysplasia with hypothyroidism and ciliary dyskinesia30.1EDAR, EDARADD
4ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive30.0EDAR, EDARADD
5ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive29.1EDA, EDAR, EDARADD
6anhidrosis26.8ACHE, COG6, EDA, EDAR, EDARADD, GLA
7hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome11.9
8ectodermal dysplasia 3, witkop type11.1
9ichthyosis, congenital, autosomal recessive 1111.0
10hartnup disorder10.9
11ameloonychohypohidrotic syndrome10.9
12ichthyosis-hypotrichosis syndrome10.9
13ectodermal dysplasia10.5
14fabry disease10.5
15naegeli-franceschetti-jadassohn syndrome10.5
16icos-related common variable immune deficiency10.2EDAR, EDARADD
17cholinergic urticaria10.2
18urticaria10.2
19sebaceous adenocarcinoma10.1KRT14, TP63
20alopecia10.1
21miliaria10.1
22adenoid squamous cell carcinoma10.0KRT14, TP63
23epidermolysis bullosa simplex, dowling-meara type10.0KRT14, TP63
24alpha 1-antitrypsin deficiency10.0KRT14, TP63
25mycosis fungoides10.0
26hypotrichosis10.0
27shaheen syndrome10.0
28hallermann-streiff syndrome9.9KRT14, TP63
29leprosy9.9
30basal cell carcinoma9.9
31rapp-hodgkin syndrome9.8
32dermatopathia pigmentosa reticularis9.8
33ectodermal dysplasia 1, hypohidrotic, x-linked9.8
34hay-wells syndrome9.8
35congenital ichthyosiform erythroderma9.8
36lelis syndrome9.8
37mature cataract9.8EDA, EDARADD
38rothmund-thomson syndrome9.7
39bazex syndrome9.7
40lymphedema9.7
41sialadenitis9.7
42lepromatous leprosy9.7
43miliaria rubra9.7
44respiratory failure9.7
45horner's syndrome9.7
46autonomic neuropathy9.7
47adie syndrome9.7
48polyneuropathy9.7
49dermatitis9.7
50atopic dermatitis9.7

Graphical network of the top 20 diseases related to Hypohidrosis:



Diseases related to hypohidrosis

Symptoms for Hypohidrosis

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UMLS symptoms related to Hypohidrosis:


unmasking of previously unidentified disease, autoresuscitation, fat tissue decreased, sensitivity to weather change, glassy eye, injection related reaction, disease prodromal stage, apparent death, meteoropathy, dark circles under eyes, foaming at mouth, unevaluable event, tissue anoxia, secretion discharge, infusion related reaction, peripheral swelling, local reaction, concomitant disease aggravated, local swelling, general signs and symptoms nec, hot flushes, yellow complexion, single organ dysfunction, purulent discharge, cold sweat, general symptom, rales, night sweats, flushing

Drugs & Therapeutics for Hypohidrosis

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Drugs for Hypohidrosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Nitroprussideapproved5815078-28-111963622
Synonyms:
13755-38-9 (di-hydrochloride salt, diH20)
14402-89-2 (di-hydrochloride salt)
15078-28-1
C07269
CHEMBL74115
CID11953891
Disodium nitroprusside dihydrate
LS-187044
Nipride
Nitroferricyanide
 
Nitropress
Nitroprusside
Pentacyanidonitrosylferrate(2-)
Sodium Nitroprusside
Sodium nitroferricyanide dihydrate
Sodium nitroprusside
Sodium nitroprusside dihydrate
Sodium nitroprusside extra pure
UNII-169D1260KM
[Fe(CN)5(NO)](2-)
nitroferricyanide
2
Acetylcholineexperimental68951-84-3187
Synonyms:
ACh
Acetyl choline ion
Acetylcholine Chloride
Acetylcholine cation
 
Acetylcholinium: acetyl-Choline
Choline acetate
Choline acetate (ester)
Miochol E
O-Acetylcholine
acetylcholine chloride

Interventional clinical trials:

idNameStatusNCT IDPhase
1An Open-Label Clinical Trial of Replagal Enzyme Therapy in Children Ages 7-17 Years With Fabry DiseaseCompletedNCT00071877Phase 2
2Dosing Study of Replagal in Patients With Fabry DiseaseCompletedNCT00068107Phase 2
3Improving Autonomic Function and Balance in Diabetic NeuropathyRecruitingNCT01864460Phase 2
4Gene Therapy for Gaucher's and Fabry Disease Using Viruses and Blood-Forming CellsCompletedNCT00001234Phase 1
5Vasodilation in Patients With Fabry's DiseaseCompletedNCT00001774
6Analysis of the Nervous System in Patients With Fabry's DiseaseCompletedNCT00001491
7Pilot Study of the Effect of Laser on Reversing Chronic Radiation InjuryRecruitingNCT01910818
8Enzyme Replacement Therapy in Fabry DiseaseTerminatedNCT00149318

Search NIH Clinical Center for Hypohidrosis


Cochrane evidence based reviews: hypohidrosis

Genetic Tests for Hypohidrosis

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Anatomical Context for Hypohidrosis

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MalaCards organs/tissues related to Hypohidrosis:

33
Skin, B cells, Myeloid, Eye, Lung, Brain, Endothelial

Animal Models for Hypohidrosis or affiliated genes

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MGI Mouse Phenotypes related to Hypohidrosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.3EDAR, EDARADD, KRT14
2MP:00053888.3ACHE, EDARADD, KRT14, TP63
3MP:00053827.3ACHE, EDAR, EDARADD, KRT14, TP63
4MP:00053917.2ACHE, EDAR, EDARADD, GLA, KRT14, TP63
5MP:00053787.1ACHE, EDAR, EDARADD, GLA, KRT14, TP63

Publications for Hypohidrosis

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Articles related to Hypohidrosis:

(show top 50)    (show all 72)
idTitleAuthorsYear
1
Application of iodinated starch powder using an atomizer spray gun - a new and effective tool to evaluate hypohidrosis. (26452436)
2015
2
Hypohidrosis Plays a Crucial Role in the Vicious Circle of Bathing Suit Ichthyosis: A Case with Summer Exacerbation. (24158451)
2013
3
Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids. (22963521)
2013
4
Approach to hypohidrosis. (23094789)
2013
5
Horner's syndrome with a sensation of warmth due to hypohidrosis. (23903517)
2013
6
A novel syndrome of hypohidrosis and intellectual disability is linked to COG6 deficiency. (23606727)
2013
7
Detection of hypohidrosis in Japanese patients with pigmentary mosaicism. (24184501)
2013
8
Hypohidrosis induced by topiramate in an adult patient. (23773932)
2013
9
Granulysin-Bearing Cells in the Skin Lesions of Acute Graft-versus-Host Disease: Possible Mechanisms for Hypohidrosis in Graft-versus-Host Disease. (23626547)
2013
10
Hypohidrosis and hyperthermia during topiramate treatment in children. (23427516)
2012
11
A case of cholinergic urticaria associated with acquired generalized hypohidrosis and reduced acetylcholine receptors: cause and effect? (21392081)
2011
12
Granulomatous mycosis fungoides with hypohidrosis mimicking lepromatous leprosy. (21079314)
2010
13
Hypohidrosis-related symptoms in pediatric epileptic patients with topiramate. (19549063)
2010
14
Reversible hypohidrosis with topiramate therapy for chronic migraine. (20236344)
2010
15
Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management. (18217788)
2008
16
Early blistering, poikiloderma, hypohidrosis, alopecia and exocrine pancreatic hypofunction: a peculiar variant of Rothmund-Thomson syndrome? (18952524)
2008
17
Electrophysiological study in 2 children with transient hypohidrosis induced by topiramate. (19050411)
2008
18
Topiramate associated hypohidrosis and hyperthermia. (18367774)
2008
19
Hypohidrosis colocalized with Becker's naevus. (17263814)
2007
20
Ectodermal dysplasia with alopecia, onychodysplasia, hypohidrosis, keratoderma, abnormal teeth and deafness. (18032861)
2007
21
Goosefleshlike lesions and hypohidrosis. (17938352)
2007
22
Cholinergic urticaria and hypohidrosis: a clinical reappraisal. (17135748)
2006
23
Harlequin sign (hemifacial flushing and contralateral hypohidrosis) in a 4-year-old girl with Horner syndrome. (16918633)
2006
24
Hypohidrosis during topiramate treatment: a rare and reversible side effect. (16648001)
2006
25
Symptomatic and asymptomatic hypohidrosis in children under topiramate treatment. (16363346)
2005
26
Monitoring perspiration from palms of hypohidrosis patients with a stopped-flow conductometric mini-system. (15369743)
2004
27
Basaloid follicular hamartoma with eruptive milia and hypohidrosis: is there a pathogenic relationship ? (14693502)
2003
28
Transient hypohidrosis induced by topiramate. (12823583)
2003
29
Alopecia, hypohidrosis, and ulcerations in a man: mycosis fungoides. (11939819)
2002
30
Cholinergic urticaria, a new pathogenic concept: hypohidrosis due to interference with the delivery of sweat to the skin surface. (12037443)
2002
31
Hypohidrosis related to the administration of topiramate to children. (11737174)
2001
32
Sporadic Bazex-DuprAc-Christol-like syndrome: early onset basal cell carcinoma, hypohidrosis, hypotrichosis, and prominent milia. (10691946)
2000
33
Cholinergic urticaria associated with acquired generalized hypohidrosis: report of a case and review of the literature. (11069522)
2000
34
Familial mydriasis, cardiac arrhythmia, respiratory failure, muscular weakness and hypohidrosis. (11140938)
2000
35
Congenital ichthyosis, follicular atrophoderma, hypotrichosis, and hypohidrosis: a new genodermatosis? (9450882)
1998
36
The ultrastructural characteristics of eccrine sweat glands in a Fabry disease patient with hypohidrosis. (9833977)
1998
37
Familial simple hypohidrosis with abnormal palmar dermal ridges. (3228139)
1988
38
Polyneuropathy in SjAPgren's syndrome. A case of prevalently autonomic neuropathy with tonic pupil and hypohidrosis. (3056790)
1988
39
Anhidrosis (hypohidrosis) in SjAPgren's syndrome. (3819059)
1987
40
A case of hyperkeratosis palmoplantaris striata combined with pili torti, hypohidrosis, hypodontia and hypacusis. (6217715)
1982
41
The Bazex syndrome: follicular atrophoderma with multiple basal cell carcinomas, hypotrichosis and hypohidrosis. (7273474)
1981
42
An ectodermal dysplasia syndrome of alopecia, onychodysplasia, hypohidrosis, hyperkeratosis, deafness and other manifestations. (863459)
1977
43
Hyperhidrosis and hypohidrosis. (177967)
1976
44
Hyperpigmentation and hypohidrosis. (The Naegeli-Franceschetti-Jadassohn syndrome): report of a family and review of the literature. (939040)
1976
45
Hypoplastic enamel, onycholysis, and hypohidrosis inherited as an autosomal dominant trait. A review of ectodermal dysplasia syndromes. (122795)
1975
46
The effect of pretreatment of skin on artificially induced miliaria rubra and hypohidrosis. (4926865)
1971
47
Induced miliaria (prickly heat), post-miliarial hypohidrosis and some potential sequelae. (5811942)
1969
48
The effects of administration of ascorbic acid in experimentally induced miliaria and hypohidrosis in volunteers. (5775074)
1969
49
Induced miliaria, postmiliarial hypohidrosis, and some potential sequelae. (4884045)
1969
50
Holmes-Adie syndrome with segmental hypohidrosis. (15088536)
1967

Variations for Hypohidrosis

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Expression for genes affiliated with Hypohidrosis

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Search GEO for disease gene expression data for Hypohidrosis.

Pathways for genes affiliated with Hypohidrosis

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Pathways related to Hypohidrosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.2EDA, EDAR, EDARADD

GO Terms for genes affiliated with Hypohidrosis

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Cellular components related to Hypohidrosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1apical part of cellGO:00451779.6EDA, EDAR

Biological processes related to Hypohidrosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of NF-kappaB import into nucleusGO:004234610.1EDA, EDAR
2pigmentationGO:00434739.8EDA, EDAR
3positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.6EDA, EDAR
4epithelial cell differentiationGO:00308559.4KRT14, TP63
5odontogenesis of dentin-containing toothGO:00424758.9EDA, EDAR, TP63
6cell differentiationGO:00301548.7EDA, EDAR, EDARADD, TP63

Sources for Hypohidrosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet