MCID: HYP022
MIFTS: 43

Hypohidrosis malady

Skin diseases category
Download this MalaCard

Summaries for Hypohidrosis

About this section


Fully expand this MalaCard
Wikipedia:65 Hypohidrosis is diminished sweating in response to appropriate stimuli. While hyperhidrosis is a... more...

MalaCards based summary: Hypohidrosis, also known as oligohidrosis, is related to anhidrosis and ectodermal dysplasia. An important gene associated with Hypohidrosis is EDA (ectodysplasin A). The compounds mucicarmine and hematoxylin have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and brain, and related mouse phenotypes are pigmentation and limbs/digits/tail.

Aliases & Classifications for Hypohidrosis

About this section
Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH
See all sources

Hypohidrosis, Aliases & Descriptions:

Name: Hypohidrosis 8 10 44 62
 
Oligohidrosis 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


External Ids:

Disease Ontology8 DOID:11155
NCIt39 C34718
SNOMED-CT57 201189007, 45004005
MeSH34 D007007

Related Diseases for Hypohidrosis

About this section

Diseases related to Hypohidrosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 107)
idRelated DiseaseScoreTop Affiliating Genes
1anhidrosis31.2GLA
2ectodermal dysplasia30.4EDA, EDAR, TP63
3hypohidrotic ectodermal dysplasia30.1EDARADD, EDAR, EDA
4tooth agenesis10.4EDARADD
5epithelial-myoepithelial carcinoma10.4KRT14
6cholinergic urticaria10.4
7urticaria10.4
8clouston syndrome10.3EDARADD, EDAR
9alopecia10.3
10miliaria10.3
11fabry disease10.2
12mycosis fungoides10.1
13tooth and nail syndrome10.1
14hypotrichosis10.1
15ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant10.1
16myoepithelioma10.1TP63, KRT14
17hypertrophic scars10.1KRT14, TP63
18breast fibroadenoma10.1KRT14, TP63
19cervical squamous cell carcinoma10.1KRT14, TP63
20mucoepidermoid carcinoma10.1TP63, KRT14
21pleomorphic adenoma10.1KRT14, TP63
22x-linked ichthyosis10.1
23laron syndrome10.1
24basal cell carcinoma10.1
25leprosy10.1
26ameloonychohypohidrotic syndrome10.1
27hypohidrotic ectodermal dysplasia with hypothyroidism and ciliary dyskinesia10.1
28ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive10.1
29shaheen syndrome10.1
30ectodermal dysplasia 1, hypohidrotic, x-linked10.1
31salivary gland adenoid cystic carcinoma10.0KRT14, TP63
32oxyphilic adenoma10.0KRT14, TP63
33skin benign neoplasm10.0KRT14, TP63
34transitional cell carcinoma10.0KRT14, TP63
35papilloma10.0KRT14, TP63
36graft versus host disease9.9
37lymphedema9.9
38rothmund-thomson syndrome9.9
39congenital ichthyosiform erythroderma9.9
40arachnoiditis9.9
41lepromatous leprosy9.9
42sialadenitis9.9
43riley-day syndrome9.9
44adie syndrome9.9
45horner's syndrome9.9
46atopic dermatitis9.9
47miliaria rubra9.9
48autonomic neuropathy9.9
49brain stem infarction9.9
50dermatitis9.9

Graphical network of the top 20 diseases related to Hypohidrosis:



Diseases related to hypohidrosis

Symptoms for Hypohidrosis

About this section

Drugs & Therapeutics for Hypohidrosis

About this section

Drug clinical trials:

Search ClinicalTrials for Hypohidrosis

Search NIH Clinical Center for Hypohidrosis

Genetic Tests for Hypohidrosis

About this section

Anatomical Context for Hypohidrosis

About this section

MalaCards organs/tissues related to Hypohidrosis:

32
Skin, Bone, Brain, Testes

Animal Models for Hypohidrosis or affiliated genes

About this section

Publications for Hypohidrosis

About this section

Articles related to Hypohidrosis:

(show top 50)    (show all 67)
idTitleAuthorsYear
1
Hypohidrosis Plays a Crucial Role in the Vicious Circle of Bathing Suit Ichthyosis: A Case with Summer Exacerbation. (24158451)
2013
2
Successful treatment of syringotropic CD8+ mycosis fungoides accompanied by hypohidrosis with vorinostat and retinoids. (22963521)
2013
3
Approach to hypohidrosis. (23094789)
2013
4
Horner's syndrome with a sensation of warmth due to hypohidrosis. (23903517)
2013
5
A novel syndrome of hypohidrosis and intellectual disability is linked to COG6 deficiency. (23606727)
2013
6
Detection of hypohidrosis in Japanese patients with pigmentary mosaicism. (24184501)
2013
7
Hypohidrosis induced by topiramate in an adult patient. (23773932)
2013
8
Granulysin-Bearing Cells in the Skin Lesions of Acute Graft-versus-Host Disease: Possible Mechanisms for Hypohidrosis in Graft-versus-Host Disease. (23626547)
2013
9
Hypohidrosis and hyperthermia during topiramate treatment in children. (23427516)
2012
10
A case of cholinergic urticaria associated with acquired generalized hypohidrosis and reduced acetylcholine receptors: cause and effect? (21392081)
2011
11
Granulomatous mycosis fungoides with hypohidrosis mimicking lepromatous leprosy. (21079314)
2010
12
Hypohidrosis-related symptoms in pediatric epileptic patients with topiramate. (19549063)
2010
13
Reversible hypohidrosis with topiramate therapy for chronic migraine. (20236344)
2010
14
Drug-induced hyperhidrosis and hypohidrosis: incidence, prevention and management. (18217788)
2008
15
Early blistering, poikiloderma, hypohidrosis, alopecia and exocrine pancreatic hypofunction: a peculiar variant of Rothmund-Thomson syndrome? (18952524)
2008
16
Electrophysiological study in 2 children with transient hypohidrosis induced by topiramate. (19050411)
2008
17
Topiramate associated hypohidrosis and hyperthermia. (18367774)
2008
18
Hypohidrosis colocalized with Becker's naevus. (17263814)
2007
19
Ectodermal dysplasia with alopecia, onychodysplasia, hypohidrosis, keratoderma, abnormal teeth and deafness. (18032861)
2007
20
Goosefleshlike lesions and hypohidrosis. (17938352)
2007
21
Cholinergic urticaria and hypohidrosis: a clinical reappraisal. (17135748)
2006
22
Harlequin sign (hemifacial flushing and contralateral hypohidrosis) in a 4-year-old girl with Horner syndrome. (16918633)
2006
23
Hypohidrosis during topiramate treatment: a rare and reversible side effect. (16648001)
2006
24
A 52-year-old man with hypohidrosis. (17203598)
2006
25
Symptomatic and asymptomatic hypohidrosis in children under topiramate treatment. (16363346)
2005
26
Monitoring perspiration from palms of hypohidrosis patients with a stopped-flow conductometric mini-system. (15369743)
2004
27
Basaloid follicular hamartoma with eruptive milia and hypohidrosis: is there a pathogenic relationship ? (14693502)
2003
28
Transient hypohidrosis induced by topiramate. (12823583)
2003
29
Alopecia, hypohidrosis, and ulcerations in a man: mycosis fungoides. (11939819)
2002
30
Cholinergic urticaria, a new pathogenic concept: hypohidrosis due to interference with the delivery of sweat to the skin surface. (12037443)
2002
31
Hypohidrosis related to the administration of topiramate to children. (11737174)
2001
32
Sporadic Bazex-DuprAc-Christol-like syndrome: early onset basal cell carcinoma, hypohidrosis, hypotrichosis, and prominent milia. (10691946)
2000
33
Cholinergic urticaria associated with acquired generalized hypohidrosis: report of a case and review of the literature. (11069522)
2000
34
Familial mydriasis, cardiac arrhythmia, respiratory failure, muscular weakness and hypohidrosis. (11140938)
2000
35
Congenital ichthyosis, follicular atrophoderma, hypotrichosis, and hypohidrosis: a new genodermatosis? (9450882)
1998
36
The ultrastructural characteristics of eccrine sweat glands in a Fabry disease patient with hypohidrosis. (9833977)
1998
37
Familial simple hypohidrosis with abnormal palmar dermal ridges. (3228139)
1988
38
Polyneuropathy in SjAPgren's syndrome. A case of prevalently autonomic neuropathy with tonic pupil and hypohidrosis. (3056790)
1988
39
Anhidrosis (hypohidrosis) in SjAPgren's syndrome. (3819059)
1987
40
A case of hyperkeratosis palmoplantaris striata combined with pili torti, hypohidrosis, hypodontia and hypacusis. (6217715)
1982
41
The Bazex syndrome: follicular atrophoderma with multiple basal cell carcinomas, hypotrichosis and hypohidrosis. (7273474)
1981
42
An ectodermal dysplasia syndrome of alopecia, onychodysplasia, hypohidrosis, hyperkeratosis, deafness and other manifestations. (863459)
1977
43
Hyperhidrosis and hypohidrosis. (177967)
1976
44
Hyperpigmentation and hypohidrosis. (The Naegeli-Franceschetti-Jadassohn syndrome): report of a family and review of the literature. (939040)
1976
45
Hypoplastic enamel, onycholysis, and hypohidrosis inherited as an autosomal dominant trait. A review of ectodermal dysplasia syndromes. (122795)
1975
46
The effect of pretreatment of skin on artificially induced miliaria rubra and hypohidrosis. (4926865)
1971
47
Induced miliaria (prickly heat), post-miliarial hypohidrosis and some potential sequelae. (5811942)
1969
48
The effects of administration of ascorbic acid in experimentally induced miliaria and hypohidrosis in volunteers. (5775074)
1969
49
Induced miliaria, postmiliarial hypohidrosis, and some potential sequelae. (4884045)
1969
50
Holmes-Adie syndrome with segmental hypohidrosis. (15088536)
1967

Variations for Hypohidrosis

About this section

Expression for genes affiliated with Hypohidrosis

About this section
Expression patterns in normal tissues for genes affiliated with Hypohidrosis

Search GEO for disease gene expression data for Hypohidrosis.

Pathways for genes affiliated with Hypohidrosis

About this section

Compounds for genes affiliated with Hypohidrosis

About this section
Sources:
44Novoseek
See all sources

Compounds related to Hypohidrosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1mucicarmine449.5KRT14, TP63
2hematoxylin449.5KRT14, TP63
32-methoxyethanol449.3KRT14, GLA, TP63
4glutaraldehyde449.0GLA, ACHE
5arginine448.8EDA, TP63, GLA, KRT14

GO Terms for genes affiliated with Hypohidrosis

About this section

Cellular components related to Hypohidrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.5KRT24, KRT14
2apical part of cellGO:0451779.5EDAR, EDA

Biological processes related to Hypohidrosis according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1trachea gland developmentGO:06115310.0EDARADD, EDA
2salivary gland cavitationGO:0606629.9EDAR, EDA
3positive regulation of NF-kappaB import into nucleusGO:0423469.9EDA, EDAR
4pigmentationGO:0434739.8EDAR, EDA
5epidermis developmentGO:0085449.7KRT14, EDAR
6hair follicle developmentGO:0019429.7EDAR, EDARADD
7cell differentiationGO:0301549.2EDA, EDARADD, EDAR
8odontogenesis of dentin-containing toothGO:0424759.1TP63, EDAR, EDARADD, EDA

Molecular functions related to Hypohidrosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.3TAB2, KRT14, GLA, ACHE, TP63, EDAR

Products for genes affiliated with Hypohidrosis

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Hypohidrosis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet