Aliases & Classifications for Hypokalemia

MalaCards integrated aliases for Hypokalemia:

Name: Hypokalemia 12 72 28 51 41 14
Potassium Deficiency Disorder 12 69
Potassium Deficiency 72 69
Hypopotassemia 12
Potassium 40

Classifications:



External Ids:

Disease Ontology 12 DOID:4500
MeSH 41 D007008
NCIt 46 C34939
ICD10 32 E87.6

Summaries for Hypokalemia

MedlinePlus : 40 Potassium is a mineral that your body needs to work properly. It is a type of electrolyte. It helps your nerves to function and muscles to contract. It helps your heartbeat stay regular. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure. Many people get all the potassium they need from what they eat and drink. Sources of potassium in the diet include Leafy greens, such as spinach and collards Fruit from vines, such as grapes and blackberries Root vegetables, such as carrots and potatoes Citrus fruits, such as oranges and grapefruit Your kidneys help to keep the right amount of potassium in your body. If you have chronic kidney disease, your kidneys may not remove extra potassium from the blood. Some medicines also can raise your potassium level. You may need a special diet to lower the amount of potassium that you eat.

MalaCards based summary : Hypokalemia, also known as potassium deficiency disorder, is related to seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance and diabetes insipidus, nephrogenic, autosomal. An important gene associated with Hypokalemia is SLC12A3 (Solute Carrier Family 12 Member 3), and among its related pathways/superpathways are Peptide hormone metabolism and ACE Inhibitor Pathway, Pharmacodynamics. The drugs Dopamine and Furosemide have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and lung, and related phenotypes are Decreased shRNA abundance and behavior/neurological

Wikipedia : 72 Hypokalemia, also spelled hypokalaemia, is a low level of potassium (K+) in the blood serum. Normal... more...

Related Diseases for Hypokalemia

Diseases related to Hypokalemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 247)
# Related Disease Score Top Affiliating Genes
1 seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance 32.0 AQP2 SLC12A3
2 diabetes insipidus, nephrogenic, autosomal 31.9 AQP2 CASR SLC12A1
3 liddle syndrome 31.6 HSD11B2 NR3C2 REN
4 hyperaldosteronism, familial, type i 30.9 HSD11B2 NR3C2 POMC REN
5 gitelman syndrome 30.7 BSND CASR CLCNKB KCNJ1 REN SLC12A1
6 apparent mineralocorticoid excess 30.5 CLCNKB HSD11B2 NR3C2 POMC REN
7 bartter disease 30.0 BSND CASR CLCNKB KCNJ1 REN SLC12A1
8 chondrocalcinosis 29.7 CASR REN SLC12A3
9 malignant hypertension 29.7 ACE REN
10 bartter syndrome, type 3 29.7 BSND CLCNKB KCNJ1 REN SLC12A1 SLC12A3
11 hyporeninemic hypoaldosteronism 29.6 ACE REN
12 hypoaldosteronism 29.6 ACE POMC REN
13 chronic kidney failure 29.4 ACE CASR REN
14 fibromuscular dysplasia 29.4 ACE REN
15 nephrocalcinosis 29.2 CLCNKB KCNJ1 SLC12A1
16 diabetes insipidus 29.2 AQP2 POMC REN SLC12A1
17 congestive heart failure 28.8 ACE AQP2 NR3C2 REN
18 conn's syndrome 27.9 ACE CLCNKB HSD11B2 NR3C2 POMC REN
19 hypertension, essential 27.9 ACE HSD11B2 NR3C2 POMC REN SLC12A1
20 myotonia, potassium-aggravated 12.4
21 hypertensive hypokalemia familial 11.9
22 sodium-potassium-atpase activity of red cell 11.9
23 vipoma 11.6
24 thyrotoxic periodic paralysis 11.4
25 renal tubular acidosis, distal 11.4
26 thyrotoxic periodic paralysis 1 11.3
27 wdha syndrome 11.2
28 hypokalemic periodic paralysis, type 1 11.1
29 hypocalcemia, autosomal dominant 1 11.1
30 thyrotoxic periodic paralysis 2 11.1
31 hypokalemic alkalosis, familial, with specific renal tubulopathy 11.1
32 hypomagnesemia 2, renal 11.0
33 kindler syndrome 10.9
34 diarrhea 1, secretory chloride, congenital 10.8
35 bartter syndrome, type 5, antenatal, transient 10.8
36 diabetes insipidus, nephrogenic, x-linked 10.8
37 hyperaldosteronism, familial, type ii 10.8
38 primary aldosteronism, seizures, and neurologic abnormalities 10.8
39 primary hypomagnesemia 10.8
40 hyper-reninism 10.8
41 slc4a1-associated distal renal tubular acidosis 10.8
42 acute adrenal insufficiency 10.4 POMC REN
43 impaired renal function disease 10.3 AQP2 SLC12A1
44 suprasellar meningioma 10.3 POMC REN
45 adrenal cortical hypofunction 10.3 POMC REN
46 hypercalciuria, absorptive, 2 10.3 CASR KCNJ1
47 pseudohypoaldosteronism, type i, autosomal dominant 10.3 NR3C2 REN
48 corticosteroid-binding globulin deficiency 10.2 HSD11B2 POMC
49 familial glucocorticoid deficiency 10.2 POMC REN
50 renal artery obstruction 10.2 ACE REN

Graphical network of the top 20 diseases related to Hypokalemia:



Diseases related to Hypokalemia

Symptoms & Phenotypes for Hypokalemia

GenomeRNAi Phenotypes related to Hypokalemia according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance GR00297-A 8.92 CACNA1S CLCNKB HSD11B2 KCNH2

MGI Mouse Phenotypes related to Hypokalemia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.17 POMC REN SLC12A1 NR3C2 CASR ACE
2 cardiovascular system MP:0005385 10.14 POMC REN SLC12A1 SLC12A3 NR3C2 ACE
3 growth/size/body region MP:0005378 10.11 POMC REN SLC12A1 NR3C2 CASR ACE
4 homeostasis/metabolism MP:0005376 10.1 POMC REN SLC12A1 SLC12A3 NR3C2 CASR
5 hematopoietic system MP:0005397 9.97 NR3C2 POMC REN SLC12A1 CASR ACE
6 mortality/aging MP:0010768 9.93 POMC REN SLC12A1 NR3C2 CASR ACE
7 muscle MP:0005369 9.43 NR3C2 REN CASR HSD11B2 KCNH2 CACNA1S
8 renal/urinary system MP:0005367 9.4 POMC REN SLC12A1 SLC12A3 CASR ACE

Drugs & Therapeutics for Hypokalemia

Drugs for Hypokalemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 215)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
2
Furosemide Approved, Vet_approved Phase 4,Phase 2,Phase 1,Early Phase 1 54-31-9 3440
3
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
4
Progesterone Approved, Vet_approved Phase 4 57-83-0 5994
5
Mifepristone Approved, Investigational Phase 4 84371-65-3 55245
6
Acetaminophen Approved Phase 4 103-90-2 1983
7
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
8
Spironolactone Approved Phase 4,Phase 2,Phase 3 1952-01-7, 52-01-7 5833
9
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2 58-93-5 3639
10
Amphotericin B Approved, Investigational Phase 4,Phase 2 1397-89-3 5280965 14956
11
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3 50-23-7 657311 5754
12
Procaterol Approved, Investigational Phase 4 72332-33-3 688561
13
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2 22916-47-8 4189
14
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
15
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
16
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4 7487-88-9 24083
17
Tolvaptan Approved Phase 4 150683-30-0 216237
18
Chlorothiazide Approved, Vet_approved Phase 4 58-94-6 2720
19
Metolazone Approved Phase 4 17560-51-9 4170
20 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2
21 Licorice Approved, Nutraceutical Phase 4
22
Butyric Acid Experimental, Investigational Phase 4 107-92-6 264
23 insulin Phase 4,Phase 3,Phase 2
24 diuretics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
25 Sodium Potassium Chloride Symporter Inhibitors Phase 4,Phase 2,Phase 1,Early Phase 1
26 Natriuretic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Dopamine Agents Phase 4
29 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2
30 Hypoglycemic Agents Phase 4,Phase 3
31 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1
32 Insulin, Globin Zinc Phase 4,Phase 3,Phase 2
33 Protective Agents Phase 4,Phase 2
34 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
35 Analgesics Phase 4,Phase 1,Phase 2
36 calcium channel blockers Phase 4
37 Cathartics Phase 4
38 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Central Nervous System Depressants Phase 4
40 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Mineralocorticoid Receptor Antagonists Phase 4,Phase 3,Phase 2,Phase 1
42 Mineralocorticoids Phase 4,Phase 3,Phase 2,Phase 1
43 Adrenergic Agonists Phase 4,Phase 3,Phase 2,Phase 1
44 Adrenergic beta-2 Receptor Agonists Phase 4,Phase 1
45 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2,Phase 1
46 Sodium Chloride Symporter Inhibitors Phase 4,Phase 3,Phase 2
47 Steroid Synthesis Inhibitors Phase 4,Phase 2
48 Albuterol Phase 4,Phase 2
49 Gastrointestinal Agents Phase 4
50 Tocolytic Agents Phase 4,Phase 1,Phase 2

Interventional clinical trials:

(show top 50) (show all 79)

# Name Status NCT ID Phase Drugs
1 Comparison of Enteral Versus Intravenous Potassium Supplementation Unknown status NCT02015962 Phase 4 Intravenous potassium chloride;Oral potassium chloride
2 The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck Cancer Unknown status NCT01845922 Phase 4
3 Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial Unknown status NCT00937092 Phase 4 Furosemide;low-dose dopamine + low-dose furosemide
4 Effect of Licorice and Hydrochlorothiazide on Plasma Potassium Completed NCT00605202 Phase 4 Hydrochlorothiazide
5 Monocentric STUDY, Randomised Double Blinded (Healthy Subjects, or Transversal (Patients With Gitelman Syndrome) Completed NCT02297048 Phase 4
6 Safety of Continuous Potassium Chloride Infusion in Critical Care Completed NCT00718068 Phase 4 Sterile Potassium Chloride Concentrate;Sterile Potassium Chloride Concentrate
7 Safety and Effectiveness of Short-course AmBisome in the Treatment of PKDL in Bangladesh Completed NCT03311607 Phase 4 AmBisome
8 Comparative Study on the Efficacy and Safety of Procaterol Versus Salbutamol Given Via Metered Dose Inhaler With Spacer in the Management of Acute Asthma Attack in the Emergency Room Completed NCT01091337 Phase 4 Procaterol;Salbutamol
9 Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy Completed NCT01170754 Phase 4 PEG-3350 and Gatorade;Golytely 4 liters
10 Blood Pressure Regulation - Role of Potassium Completed NCT02380157 Phase 4 Kaleorid, 750mg (trade name), Potassium chloride (active substance);Placebo
11 Metabolism of Isotonic Versus Hypotonic Maintenance Solutions in Fasting Healthy Adults Completed NCT02822898 Phase 4 NaCl 0.9% in Glucose 5% with 40mEq Potassium;Glucion 5%
12 Early Diuresis Following Colorectal Surgery Completed NCT02351934 Phase 4 Furosemide;Celecoxib;Gabapentin
13 Diuretics In the Management of Essential Hypertension (DIME) Study Completed NCT00131846 Phase 4 Thiazide diuretics;No diuretics
14 PROPHYSOME: Pilot Study on Safety of a Weekly Administration of 10mg/kg of AmBisome® in Antifungal Prophylaxis Treatment of Allogeneic Stem-cell Transplantation and Acute Leukaemia Completed NCT00362544 Phase 4 Ambisome
15 Efficacy of KCl Plus 0.9%NaCl Compare With KCl Plus 0.45%NaCl Recruiting NCT02721095 Phase 4
16 Potassium Infusion for Conversion of Atrial Fibrillation/-Flutter Recruiting NCT01818583 Phase 4 Potassium chloride;Glucose 50 MG/ML
17 The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis Enrolling by invitation NCT02082717 Phase 4 potassium chloride replacement;Experimental - 4% Sodium Bicarbonate
18 Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure Enrolling by invitation NCT02606253 Phase 4 tolvaptan;Chlorothiazide;Metolazone
19 Intravenous Fluids in Hospitalised Children Not yet recruiting NCT02926989 Phase 4 Plasmalyte Glucos 50 mg/mL;0.45% saline in 5% dextrose
20 Use of Spironolactone for the Prevention of Electrolyte Abnormalities in Patients Treated With Amphotericin B Terminated NCT01843309 Phase 4 Spironolactone 100mg;Spironolactone 200mg;Placebo
21 Dopamine in Acute Decompensated Heart Failure II Terminated NCT01060293 Phase 4 High-dose furosemide;Low-dose furosemide;Low-dose furosemide combined with low-dose dopamine
22 Tight Intra-Operative Glucose Control During Coronary Artery Bypass Surgery Terminated NCT00394303 Phase 4 Intraoperative continuous insulin infusion
23 Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy Unknown status NCT00522756 Phase 3 Sodium bicarbonate;Sodium chloride
24 Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension Completed NCT00095550 Phase 3 Irbesartan/HCTZ;Irbesartan monotherapy;HCTZ monotherapy
25 Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy as First Line Treatment for Severe Hypertension Completed NCT00095394 Phase 3 Irbesartan/HCTZ;Irbesartan monotherapy
26 Hypertension Prevention in Pre-Hypertensive Individuals Completed NCT00970931 Phase 3 Chlorthalidone plus amiloride;placebo
27 Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I Hypertension Completed NCT00971165 Phase 3 losartan;Chlorthalidone plus amiloride
28 SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan. Completed NCT01096654 Phase 3
29 Vitamin K2 Supplementation to Activate Matrix Gla Protein (MGP) as Endogenous Inhibitor of Vascular Calcification in Hemodialysis Patients Completed NCT01407601 Phase 3
30 Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification Completed NCT00183001 Phase 3 Vitamin K
31 Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF) Completed NCT00141778 Phase 2, Phase 3 Placebo;Ramipril;Spironolactone
32 Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy Completed NCT00753688 Phase 3 PAZOPANIB;Placebo
33 Heart And Lung Failure - Pediatric INsulin Titration Trial Active, not recruiting NCT01565941 Phase 3 Insulin;Insulin
34 Interest of Using Balanced Fluid for Infusion at the Early Phase of an Acute Cranial Trauma for Limiting Hyperchloremic Acidosis Terminated NCT00847977 Phase 3 use of a non balced fluid and of a macromolecular fluid;use of balanced crystalloids fluid and macromolecular fluid
35 Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria Terminated NCT00638482 Phase 2, Phase 3 Hydrochlorothiazide
36 Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium Unknown status NCT02709031 Phase 1, Phase 2 Cicletanine + magnesium;Cicletanine
37 The Effects of Potassium on Glucose Metabolism in African Americans Completed NCT02236598 Phase 2 K+ supplement;Placebo
38 Input of the Use of Indometacin in Gitelman Syndrome as Compared to Potassium Sparing Diuretics Completed NCT01146197 Phase 1, Phase 2 TREATMENT
39 Modified ORS Solution for Severely Malnourished Children Completed NCT01821586 Phase 2
40 Proof-of-concept for the Aldosterone Synthase Inhibitor LCI699 in Patients With Primary Hyperaldosteronism Completed NCT00732771 Phase 2 LCI699
41 PROPHESSOR: AmBisome in Antifungal Primary Prophylaxis Treatment of High Risk Patients Undergoing Allogeneic Stem Cell Transplantation Completed NCT00326157 Phase 2 AmBisome
42 Cetuximab and Lenalidomide in Head and Neck Completed NCT01133665 Phase 2 Cetuximab and Lenalidomide
43 Hemodynamics and Extravascular Lung Water in Acute Lung Injury Completed NCT00624650 Phase 2 Diuresis (furosemide) part I;Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine);Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine);Dobutamine;Dobutamine;Diuresis (furosemide) part II
44 Vitamin K to Slow Progression of Cardiovascular Disease Risk in Hemodialysis Patients Recruiting NCT03311321 Phase 1, Phase 2
45 The Effects of Patiromer on Serum Potassium Level and Gut Microbiome of ESRD Patients With Hyperkalemia Recruiting NCT03326583 Phase 2 Patiromer
46 ToRsemide for pOstpartum HYpertension Recruiting NCT02813551 Phase 2 Torsemide;Placebo
47 Trial of Abiraterone Without Exogenous Glucocorticoids in Men With CRPC With Correlative Assessment of Hormone Intermediates. Active, not recruiting NCT02025010 Phase 2 abiraterone acetate;prednisone
48 Treatment to Reduce Vascular Calcification In Hemodialysis Patients Using Vitamin K Active, not recruiting NCT02870829 Phase 2 menaquinone-7
49 Safety and Efficacy of Chlorthalidone in Type 1 Diabetes Not yet recruiting NCT03325114 Phase 2 Chlorthalidone
50 Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study Not yet recruiting NCT03170219 Phase 2

Search NIH Clinical Center for Hypokalemia

Cochrane evidence based reviews: hypokalemia

Genetic Tests for Hypokalemia

Genetic tests related to Hypokalemia:

# Genetic test Affiliating Genes
1 Hypokalemia 28

Anatomical Context for Hypokalemia

MalaCards organs/tissues related to Hypokalemia:

38
Heart, Kidney, Lung, Prostate, Liver, Breast, Bone

Publications for Hypokalemia

Articles related to Hypokalemia:

(show top 50) (show all 671)
# Title Authors Year
1
Itraconazole induced hypertension and hypokalemia: Mechanistic evaluation. ( 29385285 )
2018
2
Prognostic Impact of Mild Hypokalemia in Terms of Death and Stroke in the General Population-A Prospective Population Study. ( 29024624 )
2018
3
Chest pain as a manifestation of hypokalemia in a pediatric patient. ( 29126579 )
2018
4
Potential Usefulness of Early Potassium Supplementation for Preventing Severe Hypokalemia Induced by Liposomal Amphotericin B in Hematologic Patients: A Retrospective Study. ( 29305017 )
2018
5
Hypokalemia associated with pseudo-Cushing's syndrome and magnesium deficiency induced by chronic alcohol abuse. ( 29450857 )
2018
6
Hypokalemia during antibiotic treatment for bone and joint infections. ( 29018986 )
2017
7
Hypokalemia at the Time of Admission to the Intensive Care Unit (ICU) Increases the Need for Mechanical Ventilation and Time of Ventilation in Critically Ill Trauma Patients. ( 28620594 )
2017
8
Persistent hypokalemia with renal losses in a 31-year-old pregnant woman. ( 28732701 )
2017
9
Hypokalemia with Trifluoperazine at Therapeutic Dose. ( 28615774 )
2017
10
Analysis of Hypokalemia as a Side Effect of Liposomal Amphotericin in Pediatric Patients. ( 28945677 )
2017
11
Increased afterload following myocardial infarction promotes conduction-dependent arrhythmias that are unmasked by hypokalemia. ( 28798965 )
2017
12
Hyperkalemia and Hypokalemia in CKD: Prevalence, Risk Factors, and Clinical Outcomes. ( 29031358 )
2017
13
Diospyros rhodocalyx (Tako-Na), a Thai folk medicine, associated with hypokalemia and generalized muscle weakness: a case series. ( 28617146 )
2017
14
Dextrose, hypokalemia and Torsade de Pointes. ( 28062741 )
2017
15
Secretory diarrhea and hypokalemia associated with colonic pseudo-obstruction: A case study and systematic analysis of the literature. ( 28580600 )
2017
16
Ultrasound of the diaphragm in severe hypokalemia induced diaphragmatic dysfunction. ( 29099003 )
2017
17
Recurrent Hypokalemia leading to Flaccid Quadriparesis: A Renal or Connective Tissue Disorder. ( 29220070 )
2017
18
Bowel preparation for colonoscopy and hypokalemia: at the heart of the problem! ( 28917345 )
2017
19
A Rare Cause of Severe Hypokalemia and Back Pain. ( 28881192 )
2017
20
Torsade de Pointes Induced by Hypokalemia from Imipenem and Piperacillin. ( 28638664 )
2017
21
An Overlooked Cause of Hypokalemia. ( 28687268 )
2017
22
Persistent severe hypokalemia: Gitelman syndrome and differential diagnosis. ( 29044344 )
2017
23
Reversible Hypokalemia and Bartter-Like Syndrome during Prolonged Systemic Therapy with Colistimethate Sodium in an Adult Patient. ( 28699114 )
2017
24
Meropenem Induced Hypokalemia. ( 28969183 )
2017
25
Central pontine myelinolysis associated with hypokalemia in a diabetic patient with sepsis. ( 28488657 )
2017
26
Tumour genesis syndrome: severe hypophosphatemia and hypokalemia may be ominous presenting findings in childhood acute myeloid leukaemia. ( 28474100 )
2017
27
Hypokalemia due to excessive cola consumption. ( 28736066 )
2017
28
Effect of Hypokalemia on Functional Outcome at 3 Months Post-Stroke Among First-Ever Acute Ischemic Stroke Patients. ( 28600907 )
2017
29
Favorable surgical outcomes of aldosterone-producing adenoma based on lateralization by CT imaging and hypokalemia: a non-AVS-based strategy. ( 28918446 )
2017
30
Hypokalemia: A potentially life-threatening complication of tenofovir therapy. ( 29163953 )
2017
31
Hypokalemia, hypomagnesemia, hypocalciuria, and recurrent tetany: Gitelman syndrome in a Chinese pedigree and literature review. ( 28469853 )
2017
32
Spironolactone is effective in treating hypokalemia among peritoneal dialysis patients. ( 29125879 )
2017
33
Temporal Pattern and Prognostic Significance of Hypokalemia in Patients Undergoing Targeted Temperature Management Following Cardiac Arrest. ( 28803654 )
2017
34
Manifestation of hyperaldosteronism related hypokalemia in a case of anorexia nervosa. ( 28962826 )
2017
35
TETANY WITH HYPOMAGNESEMIA, HYPOKALEMIA, AND HYPOCALCEMIA AS INITIAL PRESENTATION OF CELIAC DISEASE. ( 28727665 )
2017
36
Quiz Page July 2017: An Unusual Cause of Hypokalemia. ( 28646983 )
2017
37
Incidence and determinants of hyperkalemia and hypokalemia in a large healthcare system. ( 28735756 )
2017
38
Hypokalemia Presenting as Acute Psychosis. ( 28782327 )
2017
39
Weakness, Hypokalemia, and Dengue. ( 29189559 )
2017
40
Hypokalemia in dengue fever- A descriptive study. ( 27727941 )
2016
41
Hyponatremia, Hypokalemia, Hypochloremia, and Other Abnormalities. ( 27235468 )
2016
42
Hypokalemia & SVT in canabis intoxication. ( 27727874 )
2016
43
Inconceivable Hypokalemia: A Case Report of Acute Severe Barium Chloride Poisoning. ( 27840643 )
2016
44
Osmotic demyelination syndrome after slow sodium administration in a hyponatremic patient with concurrent hypokalemia. ( 27592460 )
2016
45
Hypercortisolism Manifesting as Severe Weight Loss, Hypokalemia, and Hyperglycemia in the Emergency Department. ( 26896288 )
2016
46
Cicletanine-induced hyponatremia and hypokalemia in kidney transplant patients. ( 27668156 )
2016
47
Hypokalemia during acute metabolic acidosis on hemodilution with succinylated gelatin in rats. ( 28032570 )
2016
48
Non-Cardiac Symptoms of Moderate to Severe Hypokalemia in a Patient with a Syncardiaa8c Total Artificial Heart. ( 26913677 )
2016
49
Two cases of severe hypokalemia in explosion victims. ( 27044561 )
2016
50
Hypophosphatemia, Hypomagnesemia, and Hypokalemia in Pediatric Patients Before and During Exclusive Individualized Parenteral Nutrition. ( 26869613 )
2016

Variations for Hypokalemia

Expression for Hypokalemia

Search GEO for disease gene expression data for Hypokalemia.

Pathways for Hypokalemia

GO Terms for Hypokalemia

Cellular components related to Hypokalemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.77 ACE AQP2 BSND CACNA1S CASR CLCNKB
2 basolateral plasma membrane GO:0016323 9.5 AQP2 BSND CASR
3 apical plasma membrane GO:0016324 9.46 AQP2 CASR SLC12A1 SLC12A3
4 plasma membrane GO:0005886 9.36 ACE AQP2 BSND CACNA1S CASR CLCNKB
5 integral component of membrane GO:0016021 10 ACE AQP2 BSND CACNA1S CASR CLCNKB

Biological processes related to Hypokalemia according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 ion transmembrane transport GO:0034220 9.71 AQP2 BSND CLCNKB SLC12A1
2 potassium ion transport GO:0006813 9.69 KCNH2 KCNJ1 SLC12A1
3 ion transport GO:0006811 9.63 CACNA1S CLCNKB KCNH2 KCNJ1 SLC12A1 SLC12A3
4 regulation of ion transmembrane transport GO:0034765 9.62 CACNA1S CLCNKB KCNH2 KCNJ1
5 regulation of blood pressure GO:0008217 9.54 ACE POMC REN
6 membrane depolarization during action potential GO:0086010 9.52 CACNA1S KCNH2
7 regulation of anion transmembrane transport GO:1903959 9.49 BSND CLCNKB
8 amyloid-beta metabolic process GO:0050435 9.46 ACE REN
9 angiotensin maturation GO:0002003 9.43 ACE REN
10 excretion GO:0007588 9.43 AQP2 CLCNKB KCNJ1
11 transmembrane transport GO:0055085 9.43 AQP2 CACNA1S CLCNKB KCNH2 SLC12A1 SLC12A3
12 chloride transmembrane transport GO:1902476 8.92 BSND CLCNKB SLC12A1 SLC12A3
13 transport GO:0006810 10.02 AQP2 CACNA1S CLCNKB KCNH2 KCNJ1 SLC12A1

Molecular functions related to Hypokalemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 9.32 HSD11B2 NR3C2
2 inward rectifier potassium channel activity GO:0005242 9.26 KCNH2 KCNJ1
3 voltage-gated chloride channel activity GO:0005247 9.16 BSND CLCNKB
4 cation:chloride symporter activity GO:0015377 8.96 SLC12A1 SLC12A3
5 voltage-gated ion channel activity GO:0005244 8.92 CACNA1S CLCNKB KCNH2 KCNJ1

Sources for Hypokalemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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