MCID: HYP005
MIFTS: 51

Hypokalemia malady

Categories: Metabolic diseases

Aliases & Classifications for Hypokalemia

Aliases & Descriptions for Hypokalemia:

Name: Hypokalemia 12 29 52 42 14
Potassium Deficiency Disorder 12 69
Hypopotassemia 12
Potassium 41

Classifications:



External Ids:

Disease Ontology 12 DOID:4500
MeSH 42 D007008
NCIt 47 C34939
ICD10 33 E87.6
UMLS 69 C1514284

Summaries for Hypokalemia

MedlinePlus : 41 potassium is a mineral that your body needs to work properly. it is a type of electrolyte. it helps your nerves to function and muscles to contract. it helps your heartbeat stay regular. it also helps move nutrients into cells and waste products out of cells. a diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure. many people get all the potassium they need from what they eat and drink. sources of potassium in the diet include leafy greens, such as spinach and collards fruit from vines, such as grapes and blackberries root vegetables, such as carrots and potatoes citrus fruits, such as oranges and grapefruit your kidneys help to keep the right amount of potassium in your body. if you have chronic kidney disease, your kidneys may not remove extra potassium from the blood. some medicines also can raise your potassium level. you may need a special diet to lower the amount of potassium that you eat.

MalaCards based summary : Hypokalemia, also known as potassium deficiency disorder, is related to hypertensive hypokalemia familial and myotonia congenita, atypical, acetazolamide-responsive. An important gene associated with Hypokalemia is SLC12A3 (Solute Carrier Family 12 Member 3), and among its related pathways/superpathways are Peptide hormone metabolism and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. The drugs Dopamine and Furosemide have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and lung, and related phenotypes are Decreased shRNA abundance and behavior/neurological

Wikipedia : 71 Hypokalemia, also spelled hypokalaemia, is a low level of potassium (K+) in the blood serum. Normal... more...

Related Diseases for Hypokalemia

Diseases related to Hypokalemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 208)
id Related Disease Score Top Affiliating Genes
1 hypertensive hypokalemia familial 11.8
2 myotonia congenita, atypical, acetazolamide-responsive 11.7
3 normokalemic periodic paralysis 11.7
4 gitelman syndrome 11.6
5 vipoma 11.5
6 bartter disease 11.1
7 wdha syndrome 11.1
8 hyperaldosteronism 11.1
9 thyrotoxic periodic paralysis 11.0
10 apparent mineralocorticoid excess 11.0
11 thyrotoxic periodic paralysis 1 10.9
12 diabetes insipidus, nephrogenic 10.8
13 liddle syndrome 10.8
14 sesame syndrome 10.8
15 hypokalemic periodic paralysis, type 1 10.7
16 primary aldosteronism, seizures, and neurologic abnormalities 10.7
17 hypocalcemia, autosomal dominant 10.7
18 diarrhea 1, secretory chloride, congenital 10.7
19 thyrotoxic periodic paralysis 2 10.7
20 hyper-reninism 10.7
21 slc4a1-associated distal renal tubular acidosis 10.7
22 distal monosomy 14q 10.3 POMC REN
23 hypotrichosis simplex 10.3 ACE REN
24 hyperinsulinemic hypoglycemia, familial, 3 10.2 ACE REN
25 carbohydrate metabolic disorder 10.2 ACE REN
26 hypothyroidism, congenital nongoitrous, 5 10.2 ACE REN
27 endometrial mixed adenocarcinoma 10.2 POMC REN
28 listeriosis 10.2 ACE REN
29 dientamoebiasis 10.2 ACE REN
30 iris disease 10.2 ACE REN
31 congenital nystagmus 10.2 ACE REN
32 cascade stomach 10.2 ACE REN
33 smith-mccort dysplasia 2 10.2 NR3C2 REN
34 hyperuricemic nephropathy, familial juvenile 2 10.2 ACE REN
35 petrositis 10.2 ACE REN SLC12A3
36 hypogonadism mitral valve prolapse mental retardation 10.1 ACE POMC REN
37 malignant otitis externa 10.1 POMC REN
38 dystonia 25 10.1 NR3C2 REN SLC12A3
39 deafness, autosomal recessive 79 10.1 ACE POMC REN
40 clear cell acanthoma 10.1 HSD11B2 POMC REN
41 eastern equine encephalitis 10.1 ACE REN
42 diarrhea 10.1
43 peroneal neuropathy 10.1 ACE POMC REN
44 panuveitis 10.1 NR3C2 POMC REN
45 pulmonary sarcoidosis 10.1 KCNJ1 NR3C2 SLC12A3
46 immune system organ benign neoplasm 10.1 NR3C2 POMC REN
47 prediabetes syndrome 10.1 AQP2 SLC12A1
48 body dysmorphic disorder 10.1 ACE POMC REN
49 chylocele of tunica vaginalis 10.1 ACE REN
50 dysphagia lusoria 10.1 BSND KCNJ1 REN SLC12A1

Graphical network of the top 20 diseases related to Hypokalemia:



Diseases related to Hypokalemia

Symptoms & Phenotypes for Hypokalemia

GenomeRNAi Phenotypes related to Hypokalemia according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance GR00297-A 8.92 CACNA1S CLCNKB HSD11B2 KCNH2

MGI Mouse Phenotypes related to Hypokalemia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.1 ACE AQP2 BSND CACNA1S HSD11B2 KCNJ1
2 cardiovascular system MP:0005385 10.07 ACE BSND HSD11B2 KCNH2 KCNJ1 NR3C2
3 growth/size/body region MP:0005378 10.02 ACE AQP2 BSND CACNA1S KCNH2 KCNJ1
4 homeostasis/metabolism MP:0005376 9.97 HSD11B2 KCNH2 KCNJ1 NR3C2 POMC REN
5 hematopoietic system MP:0005397 9.86 SLC12A1 ACE AQP2 BSND KCNJ1 NR3C2
6 mortality/aging MP:0010768 9.7 ACE AQP2 BSND CACNA1S HSD11B2 KCNH2
7 renal/urinary system MP:0005367 9.36 ACE AQP2 BSND CLCNKB HSD11B2 KCNJ1

Drugs & Therapeutics for Hypokalemia

Drugs for Hypokalemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 197)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
2
Furosemide Approved, Vet_approved Phase 4,Phase 2,Phase 1,Early Phase 1 54-31-9 3440
3
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2 58-93-5 3639
4
Mifepristone Approved, Investigational Phase 4 84371-65-3 55245
5
Progesterone Approved, Vet_approved Phase 4 57-83-0 5994
6
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3 50-23-7 5754 657311
7
Procaterol Approved Phase 4 72332-33-3 688561
8
Amphotericin B Approved, Investigational Phase 4,Phase 2 1397-89-3 14956 5280965
9
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2 22916-47-8 4189
10
Spironolactone Approved Phase 4,Phase 2,Phase 3 1952-01-7, 52-01-7 5833
11
Benzocaine Approved Phase 4,Phase 2 1994-09-7, 94-09-7 2337
12
Chlorothiazide Approved, Vet_approved Phase 4 58-94-6 2720
13
Metolazone Approved Phase 4 17560-51-9 4170
14
Tolvaptan Approved Phase 4 150683-30-0 216237
15 tannic acid Approved, Nutraceutical Phase 4,Phase 2
16
Butyric Acid Experimental Phase 4 107-92-6 264
17 Autonomic Agents Phase 4,Phase 3,Phase 2
18 diuretics Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
19 Dopamine Agents Phase 4
20 Natriuretic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
21 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
22 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2
23 Protective Agents Phase 4,Phase 2
24 Sodium Potassium Chloride Symporter Inhibitors Phase 4,Phase 2,Phase 1,Early Phase 1
25 Hypoglycemic Agents Phase 4
26 insulin Phase 4,Phase 2
27 Insulin, Globin Zinc Phase 4,Phase 2
28 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1
29 Sodium Chloride Symporter Inhibitors Phase 4,Phase 3,Phase 2
30 Adrenergic Agents Phase 4,Phase 3,Phase 2
31 Adrenergic Agonists Phase 4,Phase 3,Phase 2
32 Adrenergic beta-2 Receptor Agonists Phase 4
33 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2
34 Albuterol Phase 4,Phase 2
35 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
36 Anti-Inflammatory Agents Phase 4,Phase 1,Phase 2
37 Bronchodilator Agents Phase 4,Phase 3,Phase 2
38 Cortisol succinate Phase 4,Phase 3
39 Hydrocortisone 17-butyrate 21-propionate Phase 4,Phase 3
40 Hydrocortisone acetate Phase 4,Phase 3
41 Hydrocortisone-17-butyrate Phase 4
42 Respiratory System Agents Phase 4,Phase 3,Phase 2
43 Tocolytic Agents Phase 4,Phase 1,Phase 2
44 Cathartics Phase 4
45 Gastrointestinal Agents Phase 4
46 Laxatives Phase 4
47 Polyethylene glycol 3350 Phase 4
48 Pharmaceutical Solutions Phase 4,Phase 2,Phase 1
49 Anti-Bacterial Agents Phase 4,Phase 2
50 Antifungal Agents Phase 4,Phase 2

Interventional clinical trials:

(show top 50) (show all 69)
id Name Status NCT ID Phase
1 Comparison of Enteral Versus Intravenous Potassium Supplementation Unknown status NCT02015962 Phase 4
2 The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck Cancer Unknown status NCT01845922 Phase 4
3 Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial Unknown status NCT00937092 Phase 4
4 Effect of Licorice and Hydrochlorothiazide on Plasma Potassium Completed NCT00605202 Phase 4
5 Monocentric STUDY, Randomised Double Blinded (Healthy Subjects, or Transversal (Patients With Gitelman Syndrome) Completed NCT02297048 Phase 4
6 Safety of Continuous Potassium Chloride Infusion in Critical Care Completed NCT00718068 Phase 4
7 Comparative Study on the Efficacy and Safety of Procaterol Versus Salbutamol Given Via Metered Dose Inhaler With Spacer in the Management of Acute Asthma Attack in the Emergency Room Completed NCT01091337 Phase 4
8 Miralax (PEG 3350) vs. Golytely as Bowel Preparation for Screening Colonoscopy Completed NCT01170754 Phase 4
9 Blood Pressure Regulation - Role of Potassium Completed NCT02380157 Phase 4
10 Metabolism of Isotonic Versus Hypotonic Maintenance Solutions in Fasting Healthy Adults Completed NCT02822898 Phase 4
11 Diuretics In the Management of Essential Hypertension (DIME) Study Completed NCT00131846 Phase 4
12 PROPHYSOME: Pilot Study on Safety of a Weekly Administration of 10mg/kg of AmBisome® in Antifungal Prophylaxis Treatment of Allogeneic Stem-cell Transplantation and Acute Leukaemia Completed NCT00362544 Phase 4
13 Efficacy of KCl Plus 0.9%NaCl Compare With KCl Plus 0.45%NaCl Recruiting NCT02721095 Phase 4
14 Potassium Infusion for Conversion of Atrial Fibrillation/-Flutter Recruiting NCT01818583 Phase 4
15 The Impact of Neut During KCL Replacement on Pain and Incidence of Phlebitis Enrolling by invitation NCT02082717 Phase 4
16 Comparison of Oral or Intravenous Thiazides vs Tolvaptan in Diuretic Resistant Decompensated Heart Failure Enrolling by invitation NCT02606253 Phase 4
17 Intravenous Fluids in Hospitalised Children Not yet recruiting NCT02926989 Phase 4
18 Use of Spironolactone for the Prevention of Electrolyte Abnormalities in Patients Treated With Amphotericin B Terminated NCT01843309 Phase 4
19 Dopamine in Acute Decompensated Heart Failure II Terminated NCT01060293 Phase 4
20 Tight Intra-Operative Glucose Control During Coronary Artery Bypass Surgery Terminated NCT00394303 Phase 4
21 Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy Unknown status NCT00522756 Phase 3
22 Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension Completed NCT00095550 Phase 3
23 Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy as First Line Treatment for Severe Hypertension Completed NCT00095394 Phase 3
24 Hypertension Prevention in Pre-Hypertensive Individuals Completed NCT00970931 Phase 3
25 Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I Hypertension Completed NCT00971165 Phase 3
26 SPARTACUS: Subtyping Primary Aldosteronism: a Randomized Trial Comparing Adrenal Vein Sampling and Computed Tomography Scan. Completed NCT01096654 Phase 3
27 Vitamin K2 Supplementation to Activate Matrix Gla Protein (MGP) as Endogenous Inhibitor of Vascular Calcification in Hemodialysis Patients Completed NCT01407601 Phase 3
28 Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification Completed NCT00183001 Phase 3
29 Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF) Completed NCT00141778 Phase 2, Phase 3
30 Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy Completed NCT00753688 Phase 3
31 Interest of Using Balanced Fluid for Infusion at the Early Phase of an Acute Cranial Trauma for Limiting Hyperchloremic Acidosis Terminated NCT00847977 Phase 3
32 Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria Terminated NCT00638482 Phase 2, Phase 3
33 The Effects of Potassium on Glucose Metabolism in African Americans Completed NCT02236598 Phase 2
34 Input of the Use of Indometacin in Gitelman Syndrome as Compared to Potassium Sparing Diuretics Completed NCT01146197 Phase 1, Phase 2
35 Modified ORS Solution for Severely Malnourished Children Completed NCT01821586 Phase 2
36 Proof-of-concept for the Aldosterone Synthase Inhibitor LCI699 in Patients With Primary Hyperaldosteronism Completed NCT00732771 Phase 2
37 PROPHESSOR: AmBisome in Antifungal Primary Prophylaxis Treatment of High Risk Patients Undergoing Allogeneic Stem Cell Transplantation Completed NCT00326157 Phase 2
38 Cetuximab and Lenalidomide in Head and Neck Completed NCT01133665 Phase 2
39 Hemodynamics and Extravascular Lung Water in Acute Lung Injury Completed NCT00624650 Phase 2
40 Treatment to Reduce Vascular Calcification In Hemodialysis Patients Using Vitamin K Recruiting NCT02870829 Phase 2
41 ToRsemide for pOstpartum HYpertension Recruiting NCT02813551 Phase 2
42 Phase II Clinical Trial of Abiraterone Acetate Without Exogenous Glucocorticoids in Men With Castration-resistant Prostate Cancer With Correlative Assessment of Hormone Intermediates. Active, not recruiting NCT02025010 Phase 2
43 Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium Not yet recruiting NCT02709031 Phase 1, Phase 2
44 Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study Not yet recruiting NCT03170219 Phase 2
45 Evaluation of an Anti-cancer Immunotherapy Combined With Standard Neoadjuvant Treatment in Patients With WT1-positive Primary Invasive Breast Cancer Terminated NCT01220128 Phase 2
46 A Study of Safety and Clinical Activity of Immunotherapy Plus Chemotherapy in Metastatic Melanoma Patients Terminated NCT00849875 Phase 2
47 A Study to Investigate the Safety and Efficacy of a Novel Furosemide Regimen Withdrawn NCT02721511 Phase 1, Phase 2
48 GSK159802 In Healthy Male Subjects And Asthmatics Completed NCT00364273 Phase 1
49 A Pilot Study of Potassium Supplementation for Adult Patients With Rheumatoid Arthritis Completed NCT00461448 Phase 1
50 Metabolic Syndrome and Insulin Resistance in Primary Aldosteronism Unknown status NCT00173082

Search NIH Clinical Center for Hypokalemia

Cochrane evidence based reviews: hypokalemia

Genetic Tests for Hypokalemia

Genetic tests related to Hypokalemia:

id Genetic test Affiliating Genes
1 Hypokalemia 29

Anatomical Context for Hypokalemia

MalaCards organs/tissues related to Hypokalemia:

39
Heart, Kidney, Lung, Liver, Colon, Brain, Pancreas

Publications for Hypokalemia

Articles related to Hypokalemia:

(show top 50) (show all 634)
id Title Authors Year
1
Hypokalemia, hypomagnesemia, hypocalciuria, and recurrent tetany: Gitelman syndrome in a Chinese pedigree and literature review. ( 28469853 )
2017
2
Dextrose, hypokalemia and Torsade de Pointes. ( 28062741 )
2017
3
Life-threatening hyponatremia, hypokalemia, and metabolic alkalosis after intragastric balloon placement. ( 26975293 )
2016
4
Rapidly Resolving Weakness Related to Hypokalemia in Patients Infected With Dengue Virus. ( 27861219 )
2016
5
Establishing an Indicator of Hypokalemia in Patients Receiving Anti-Epidermal Growth Factor Receptor Antibodies. ( 27067850 )
2016
6
Good's syndrome and hypoparathyroidism combined with hypocalcaemia, hypokalemia, hypomagnesemia, and hypophosphatemia-Case report. ( 26875773 )
2016
7
Severe Hypokalemia with grave complication diagnosed as Bartter syndrome. ( 27728466 )
2016
8
Community-acquired hypokalemia in elderly patients: related factors and clinical outcomes. ( 28035617 )
2016
9
Inconceivable Hypokalemia: A Case Report of Acute Severe Barium Chloride Poisoning. ( 27840643 )
2016
10
A Rare Case of Hypokalemia and Hypomagnesemia. ( 26921350 )
2016
11
Non-Cardiac Symptoms of Moderate to Severe Hypokalemia in a Patient with a Syncardiaa8c Total Artificial Heart. ( 26913677 )
2016
12
Aldosterone Response in Severe Hypokalemia and Volume Depletion: A Case Report and Review of the Recent Research. ( 27525137 )
2016
13
Hypokalemia in dengue fever- A descriptive study. ( 27727941 )
2016
14
Hypokalemia associated with acute colonic pseudo-obstruction in an ESRD patient. ( 28025959 )
2016
15
Hypokalemia & SVT in canabis intoxication. ( 27727874 )
2016
16
A novel CYP11B1 mutation in a Turkish patient with 11I^-hydroxylase deficiency: An association with the severe hypokalemia leading to rhabdomyolysis. ( 27376433 )
2016
17
An Unusual Etiology of Hypokalemia in a Patient With an Eating Disorder. ( 28029538 )
2016
18
Cicletanine-induced hyponatremia and hypokalemia in kidney transplant patients. ( 27668156 )
2016
19
Hyponatremia, Hypokalemia, Hypochloremia, and Other Abnormalities. ( 27235468 )
2016
20
A Quick Reference on Hypokalemia. ( 27939864 )
2016
21
Hypokalemia during acute metabolic acidosis on hemodilution with succinylated gelatin in rats. ( 28032570 )
2016
22
Hypokalemia is a biochemical signal of poor prognosis for acute paraquat poisoning within 4A hours. ( 27395362 )
2016
23
Use of Aldosterone Antagonist to Treat Diarrhea and Hypokalemia of Ogilvie's Syndrome. ( 27812391 )
2016
24
Cardiac arrest in pregnancy - Refractory hypokalemia - Is it gitelman or type 3 bartters syndrome? ( 27728485 )
2016
25
Double Knockout of the Na+-Driven Cl-/HCO3- Exchanger and Na+/Cl- Cotransporter Induces Hypokalemia and Volume Depletion. ( 27151921 )
2016
26
Hypercortisolism Manifesting as Severe Weight Loss, Hypokalemia, and Hyperglycemia in the Emergency Department. ( 26896288 )
2016
27
Central pontine myelinolysis in Sjogren's syndrome with hypokalemia. ( 26929036 )
2016
28
Quiz Page October 2016: Severe Hypokalemia, Metabolic Alkalosis, and Malignancy. ( 27664476 )
2016
29
Malignant McKittrick-Wheelock syndrome as a cause of acute kidney injury and hypokalemia: Report of a case and review of literature. ( 27672546 )
2016
30
Ondansetron-Induced Life Threatening Hypokalemia. ( 27730793 )
2016
31
Osmotic demyelination syndrome after slow sodium administration in a hyponatremic patient with concurrent hypokalemia. ( 27592460 )
2016
32
Hypokalemia and the Disappearance of Giant Negative T Waves. ( 26935382 )
2016
33
Hypophosphatemia, Hypomagnesemia, and Hypokalemia in Pediatric Patients Before and During Exclusive Individualized Parenteral Nutrition. ( 26869613 )
2016
34
Electrolyte disturbances differentially regulate sinoatrial node and pulmonary vein electrical activity: A contribution to hypokalemia- or hyponatremia-induced atrial fibrillation. ( 26654920 )
2016
35
Reninoma: A Rare Cause of Curable Hypertension and Hypokalemia. ( 27103051 )
2016
36
Hypokalemia associated with a solitary pulmonary nodule: A case report. ( 27977570 )
2016
37
Two cases of severe hypokalemia in explosion victims. ( 27044561 )
2016
38
Does hypokalemia contribute to acute kidney injury in chronic laxative abuse? ( 26484031 )
2015
39
Resolution of Hyperreninemia, Secondary Hyperaldosteronism, and Hypokalemia With 177Lu-DOTATATE Induction and Maintenance Peptide Receptor Radionuclide Therapy in a Patient With Pancreatic Neuroendocrine Tumor. ( 26359564 )
2015
40
Pathogenesis of hypokalemia in autosomal dominant hypocalcemia type 1. ( 26323216 )
2015
41
An Unexpected Cause of Severe Hypokalemia. ( 26550501 )
2015
42
Refractory hypokalemia during barbiturate coma therapy used for treating refractory intracranial hypertension in traumatic brain injury. ( 25767595 )
2015
43
ECG Case of the Month: Unexpected Atrioventricular Conduction in High-Grade Atrioventricular Block. Sinus rhythm; high-grade second degree atrioventricular block with a junctional escape rhythm and three capture complexes, each with right bundle branch block aberration; possible septal myocardial infarct of indeterminate age; ST-T and U wave changes suggesting hypokalemia. ( 25978059 )
2015
44
Autophagic degradation of aquaporin-2 is an early event in hypokalemia-induced nephrogenic diabetes insipidus. ( 26674602 )
2015
45
Lozenge-Induced Hypermineralcorticoid State--A Unique Case of Licorice Lozenges Resulting in Hypertension and Hypokalemia. ( 26212733 )
2015
46
Gitelman's syndrome as a cause of poorly controlled hypokalemia. ( 26152628 )
2015
47
Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation. ( 26269574 )
2015
48
Medication-induced hypokalemia. ( 25798039 )
2015
49
An 18-year-old female with weight loss and hypokalemia. ( 25658211 )
2015
50
Hypokalemia-Induced Rhabdomyolysis by Primary Aldosteronism Coexistent With Sporadic Inclusion Body Myositis. ( 26605182 )
2015

Variations for Hypokalemia

Expression for Hypokalemia

Search GEO for disease gene expression data for Hypokalemia.

Pathways for Hypokalemia

GO Terms for Hypokalemia

Cellular components related to Hypokalemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.85 ACE AQP2 BSND CACNA1S CLCNKB HSD11B2
2 plasma membrane GO:0005886 9.65 ACE AQP2 BSND CACNA1S CLCNKB KCNH2
3 membrane GO:0016020 9.4 ACE AQP2 BSND CACNA1S CLCNKB HSD11B2

Biological processes related to Hypokalemia according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 transmembrane transport GO:0055085 9.83 CACNA1S CLCNKB KCNH2 SLC12A1 SLC12A3
2 ion transport GO:0006811 9.73 CACNA1S CLCNKB KCNH2 KCNJ1 SLC12A1 SLC12A3
3 potassium ion transport GO:0006813 9.7 KCNH2 KCNJ1 SLC12A1
4 regulation of ion transmembrane transport GO:0034765 9.67 CACNA1S CLCNKB KCNH2 KCNJ1
5 regulation of blood pressure GO:0008217 9.58 ACE POMC REN
6 ion transmembrane transport GO:0034220 9.55 AQP2 BSND CLCNKB KCNH2 SLC12A1
7 membrane depolarization during action potential GO:0086010 9.54 CACNA1S KCNH2
8 regulation of anion transmembrane transport GO:1903959 9.51 BSND CLCNKB
9 excretion GO:0007588 9.5 AQP2 CLCNKB KCNJ1
10 beta-amyloid metabolic process GO:0050435 9.49 ACE REN
11 angiotensin maturation GO:0002003 9.46 ACE REN
12 chloride transmembrane transport GO:1902476 9.26 BSND CLCNKB SLC12A1 SLC12A3
13 chloride transport GO:0006821 8.92 BSND CLCNKB SLC12A1 SLC12A3
14 transport GO:0006810 10.02 AQP2 CACNA1S CLCNKB KCNH2 KCNJ1 SLC12A1

Molecular functions related to Hypokalemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 steroid binding GO:0005496 9.32 HSD11B2 NR3C2
2 inward rectifier potassium channel activity GO:0005242 9.26 KCNH2 KCNJ1
3 voltage-gated chloride channel activity GO:0005247 9.16 BSND CLCNKB
4 cation:chloride symporter activity GO:0015377 8.96 SLC12A1 SLC12A3
5 voltage-gated ion channel activity GO:0005244 8.92 CACNA1S CLCNKB KCNH2 KCNJ1

Sources for Hypokalemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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