MCID: HYP017
MIFTS: 42

Hypophosphatemia malady

Category: Metabolic diseases

Aliases & Classifications for Hypophosphatemia

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Aliases & Descriptions for Hypophosphatemia:

Name: Hypophosphatemia 11 26 49 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:0050336

Summaries for Hypophosphatemia

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Wikipedia:70 Hypophosphatemia is an electrolyte disturbance in which there is an abnormally low level of phosphate in... more...

MalaCards based summary: Hypophosphatemia is related to cutaneous-skeletal hypophosphatemia syndrome and dominant hypophosphatemia with nephrolithiasis or osteoporosis. An important gene associated with Hypophosphatemia is FGF23 (Fibroblast Growth Factor 23), and among its related pathways are Osteoblast Signaling and FGF signaling pathway. The drugs ergocalciferol and sodium phosphate, dibasic have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and liver, and related mouse phenotypes are renal/urinary system and growth/size/body region.

Related Diseases for Hypophosphatemia

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Diseases related to Hypophosphatemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 160)
idRelated DiseaseScoreTop Affiliating Genes
1cutaneous-skeletal hypophosphatemia syndrome11.9
2dominant hypophosphatemia with nephrolithiasis or osteoporosis11.8
3hypophosphatemic rickets, x-linked dominant11.7
4hypophosphatemic rickets, autosomal dominant11.5
5hereditary hypophosphatemic rickets11.4
6hypophosphatemic rickets, ar11.3
7nephrolithiasis/osteoporosis, hypophosphatemic, 111.3
8hypophosphatemic rickets, autosomal recessive, 211.3
9hypophosphatemic rickets11.2
10panostotic fibrous dysplasia11.1
11oncogenic osteomalacia11.0
12hypophosphatemic rickets with hypercalciuria10.9
13vitamin d-dependent rickets, type i10.8
14tumoral calcinosis, hyperphosphatemic, familial10.7
15exostoses, multiple, type 110.7
16fanconi renotubular syndrome 110.7
17nephrolithiasis/osteoporosis, hypophosphatemic, 210.7
18dent disease10.7
19metaphyseal chondrodysplasia, murk jansen type10.7
20lowe syndrome10.7
21autosomal recessive hypophosphatemic rickets10.7
22jacobsen syndrome10.5FGF23, PHEX
23colorectal cancer, hereditary nonpolyposis, type 410.5DMP1, FGF23
24familial wilms tumor 210.5FGF23, PHEX
25immune dysregulation, polyendocrinopathy, enteropathy, x-linked syndrome10.5SLC34A1, SLC34A3
26hyperostosis10.3DMP1, FGF23, PHEX
27ochronosis10.3ENPP1, PHEX
28atelosteogenesis10.2ENPP1, FGF23, PHEX
29cystic echinococcosis10.2FGF23, PTH
30status epilepticus10.2ENPP1, FGF23, PHEX
31substance dependence10.2FGF23, PTH
32neutropenia10.2CLCN5, SLC34A1, SLC34A3
33amniotic band syndrome10.2CLCN5, SLC34A1
34rickets10.1
35achondrogenesis10.1BGLAP, PTH
36hepatitis10.1
37silver-russell syndrome due to 7p11.2p13 microduplication10.1BGLAP, CLCN5, SLC34A3
38cranial nerve palsy10.1BGLAP, PTH
39weaver syndrome 110.1BGLAP, PTH
40opthalmomandibulomelic dysplasia10.1ENPP1, PTH
41anorexia nervosa10.1
42osteomalacia10.1
43parathyroid transitional clear cell adenoma10.0BGLAP, PTH
44hip dysplasia, beukes type10.0DMP1, DSPP
45spinocerebellar ataxia, autosomal recessive 1810.0DMP1, DSPP
46hypokalemia10.0
47dyscalculia10.0BGLAP, PTH
48spastic ataxia10.0DMP1, ENPP1, FGF23, PHEX
49obesity, severe bmiq910.0BGLAP, PTH
50leukemia9.9

Graphical network of the top 20 diseases related to Hypophosphatemia:



Diseases related to hypophosphatemia

Symptoms for Hypophosphatemia

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Drugs & Therapeutics for Hypophosphatemia

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Drugs for Hypophosphatemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 79)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IronapprovedPhase 4, Phase 2, Early Phase 111237439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
2Ferric CompoundsPhase 4, Phase 2184
3Pharmaceutical SolutionsPhase 4, Phase 27793
4Trace ElementsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 15802
5MicronutrientsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 15802
6HematinicsPhase 4, Phase 21630
7
Ergocalciferolapproved, nutraceuticalPhase 3123250-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
8vitamin dPhase 31653
9VitaminsPhase 3, Phase 15095
10Calcimimetic AgentsPhase 3, Phase 169
11Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 3, Phase 1, Phase 212767
12Cinacalcet HydrochloridePhase 3, Phase 169
13HormonesPhase 3, Phase 1, Phase 213979
14Hormone AntagonistsPhase 3, Phase 1, Phase 212778
15Calcium, DietaryPhase 3, Phase 1, Phase 2, Early Phase 15525
16MitogensPhase 3, Phase 2, Phase 11526
17ErgocalciferolsPhase 31232
18Bone Density Conservation AgentsPhase 3, Phase 1, Early Phase 13266
19ImmunoglobulinsPhase 3, Phase 26045
20Immunoglobulin GPhase 3, Phase 2265
21Antibodies, MonoclonalPhase 3, Phase 23795
22AntibodiesPhase 3, Phase 26045
23Vitamin D2NutraceuticalPhase 31232
24CalciferolNutraceuticalPhase 31334
25
LenalidomideapprovedPhase 2718191732-72-6216326
Synonyms:
1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline
191732-72-6
3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
346670-73-3
443912-14-9
AC-914
AC1L50II
AKOS005146276
ALBB-015321
Bio-0168
C467567
CC 5013
CC-5013
CC-5013, Revlimid, Lenalidomide
CC5013
CDC 501
CDC-501
CDC-5013
CHEMBL848
CID216326
Celgene brand of lenalidomide
D04687
 
DB00480
EC-000.2340
ENMD-0997
I06-0831
IMID-1
IMID-5013
IMiD3
IMiD3 cpd
IMid-1
LS-184040
Lenalidomide
Lenalidomide (USAN/INN)
Lenalidomide [USAN]
MolPort-003-848-370
NCGC00167491-01
NSC747972
Revamid
Revimid
Revlimid
Revlimid (Celgene)
Revlimid (TN)
S1029_Selleck
STK639603
Thalidomide analog CC-5013
UNII-F0P408N6V4
lenalidomide
26
CetuximabapprovedPhase 2737205923-56-456842117, 2333
Synonyms:
205923-56-4
Anti EGFR
Cetuximab
Cetuximab (USAN/INN)
Cetuximab (genetical recombination)
Cetuximab (genetical recombination) (JAN)
 
Cetuximabum
Cétuximab
D03455
Erbitux
Erbitux (TN)
IMC-C225
Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer
cetuximab
27
Tenofovirapproved, investigationalPhase 2733147127-20-6464205
Synonyms:
(R)-9-(2-Phosphonomethoxypropyl)adenine
(R)-9-(2-Phosphonylmethoxypropyl)adenine
(R)-9-(2-phosphonomethoxypropyl)adenine
(R)-PMPA
147127-20-6
206184-49-8
AC-760
AC1LA9BO
Anh. tenofovir
Anhydrous tenofovir
Apropovir
CHEBI:45809
CHEMBL483
CID464205
D,L-Tenofovir
DB00300
GNA & Tenofovir
GS 1275
GS 1278
GS1278
 
HHA & Tenofovir
KS-5021
MolPort-003-850-411
NCGC00167535-01
PMPA
PMPA-(R)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Galanthus nivalis agglutinin (GNA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- & Hippeastrum hybrid agglutinin( HHA)
Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]- (9CI)
Phosphonic acid, [[2-(6-amino-9H-purin-9
S1401_Selleck
TDF
TFV
Tenefovir
Tenofovir
Tenofovir (anh.)
Tenofovir disoproxil
Tenofovir disoproxil fumarate
UNII-99YXE507IL
Viread
Viread, Tenofovir
[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid
28Protective AgentsPhase 27190
29potassium phosphatePhase 2, Phase 111
30AnticoagulantsPhase 22516
31DextransPhase 299
32Blood SubstitutesPhase 2246
33Cariostatic AgentsPhase 2318
34Iron-Dextran ComplexPhase 273
35Plasma SubstitutesPhase 2233
36Angiogenesis Modulating AgentsPhase 24072
37Immunosuppressive AgentsPhase 212770
38Anti-Bacterial AgentsPhase 210884
39Angiogenesis InhibitorsPhase 24143
40Anti-HIV AgentsPhase 23100
41Reverse Transcriptase InhibitorsPhase 21880
42Anti-Retroviral AgentsPhase 23232
43Anti-Infective AgentsPhase 221402
44Antiviral AgentsPhase 29732
45Nucleic Acid Synthesis InhibitorsPhase 24855
46Phosphorus SupplementNutraceuticalPhase 1, Phase 24
47
Sorafenibapproved, investigationalPhase 1692284461-73-0216239, 406563
Synonyms:
284461-73-0
4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide
4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate
4-(4-{3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
AB1004622
AC-1674
AC1L50CF
BAX
BAY 43-9006
BAY 43-9006 (free base)
BAY 43-9006 tosylate salt
BAY 439006
BAY 54-9085 (tosylate salt)
BAY-43-0006
BAY-43-9006
BAY-54-9085
BAY43-9006
BRD-K23984367-001-01-8
Bio-0100
CHEBI:47228
CHEBI:50924
CHEMBL1336
CID216239
 
D08524
DB00398
DB07438
EN002709
I06-0856
K00597a
Kinome_766
LS-186067
LS-187021
LS-187788
MolPort-003-850-270
N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcar bamoyl)-4-pyridyloxy)phenyl)urea
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea
NCGC00167488-01
NSC-724772
NSC747971
Nexavar
STK627350
Sorafenib
Sorafenib (INN)
Sorafenib [INN]
Sorafenib tosylate
Sorafenibum
UNII-9ZOQ3TZI87
ZINC01493878
nchembio.117-comp17
sorafenib
sorafenibum
48
DenosumabapprovedPhase 1130615258-40-7
Synonyms:
615258-40-7
AMG-162
D03684
Denosumab
 
Denosumab (USAN)
Denosumab (genetical recombination)
Denosumab (genetical recombination) (JAN)
Prolia
Xgeva
49
Nicotinamideapproved, NutraceuticalPhase 190298-92-0936
Synonyms:
.beta.-Pyridinecarboxamide
11032-50-1
123574-63-0
1yc5
3 Pyridinecarboxamide
3-Carbamoylpyridine
3-Pyridinecarboxamide
3-Pyridinecarboxylic acid amide
37321-14-5
47865U_SUPELCO
55600-01-6
63748-44-7
72340_FLUKA
72340_SIGMA
72347_FLUKA
78731-47-2
98-92-0
A186B02E-6C70-4E54-9739-79398D439AAA
AC-907/25014114
AC1L1ACZ
AC1Q4ZFV
AI3-02906
Acid amide
Amid kyseliny nikotinove
Amid kyseliny nikotinove [Czech]
Amide PP
Aminicotin
Amixicotyn
Amnicotin
Astra Brand of Niacinamide
Austrovit PP
B 3, Vitamin
B3, Vitamin
BB_NC-2290
Benicot
C00153
C6H6N2O
CCRIS 1901
CHEBI:17154
CHEMBL1140
CID936
CPD000058212
D00036
D009536
DB02701
DEA No. 1405
Delonin Amide
Delonin amide
Dipegyl
Dipigyl
EINECS 202-713-4
EINECS 234-265-0
Endobion
Enduramide
Factor pp
HMS2052M21
HMS2090B05
HMS2093H03
HSDB 1237
Hansamid
I02-1741
I02-2250
InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9
Inovitan PP
Jenapharm Brand of Niacinamide
Jenapharm, Nicotinsaureamid
LS-2051
MLS000069714
Mediatric
Merck Brand of Niacinamide
MolMap_000061
MolPort-001-783-876
N0078
N0636_SIGMA
N2142_SIGMA
N3376_SIGMA
N5535_SIAL
NAM
NCGC00093354-03
NCGC00093354-04
NSC 13128
NSC13128
NSC27452
Nandervit-N
Niacevit
Niacinamide
Niacinamide (USP)
Niacinamide Astra Brand
Niacinamide Jenapharm Brand
Niacinamide Merck Brand
 
Niacinamide Pharmagenix Brand
Niacinamide [USAN]
Niacinamide, Nicotinic acid amide, Nicotinamide
Niacotinamide
Niamide
Niavit PP
Nicamide
Nicamina
Nicamindon
Nicasir
Nicobion
Nicofort
Nicogen
Nicomidol
Nicosan 2
Nicosylamide
Nicota
Nicotamide
Nicotilamide
Nicotililamido
Nicotinamid
Nicotinamida
Nicotinamida [INN-Spanish]
Nicotinamide
Nicotinamide (JP15/INN)
Nicotinamide (Niacinamide)
Nicotinamide, niacin, vitamin B3
Nicotinamide-carbonyl-14C
Nicotinamidum
Nicotinamidum [INN-Latin]
Nicotine acid amide
Nicotine amide
Nicotinic acid amide
Nicotinic amide
Nicotinsaeureamid
Nicotinsaureamid
Nicotinsaureamid Jenapharm
Nicotinsaureamid [German]
Nicotol
Nicotylamide
Nicotylamidum
Nicovel
Nicovit
Nicovitina
Nicovitol
Nicozymin
Nictoamide
Nikasan
Nikazan
Niko-tamin
Nikotinamid
Nikotinsaeureamid
Nikotinsaeureamid [German]
Niocinamide
Niozymin
PP-Faktor
Papulex
Pelmin
Pelmine
Pelonin amide
Pharmagenix Brand of Niacinamide
Propamine A
Pyridine-3-carboxylic acid amide
S1899_Selleck
SAM001246860
SGCUT00176
SMR000058212
Savacotyl
UNII-25X51I8RD4
Vi-Nicotyl
Vi-noctyl
Vitamin B
Vitamin B (VAN)
Vitamin B 3
Vitamin B3 amide
Vitamin H1
Vitamin PP
WLN: T6NJ CVZ
Witamina PP
ZINC00005878
b-Pyridinecarboxamide
beta-Pyridinecarboxamide
bmse000281
m-(Aminocarbonyl)pyridine
nchembio.154-comp4
nchembio.73-comp6
niacin - Vitamin B3
niacinamide
nicotinamide
pyridine-3-carboxamide
to_000073
vitamin PP
50
Niacinapproved, investigational, nutraceuticalPhase 190659-67-6938
Synonyms:
3-Carboxylpyridine
3-Carboxypyridine
3-Pyridinecarboxylate
3-Pyridinecarboxylic acid
3-Pyridylcarboxylate
3-Pyridylcarboxylic acid
3-carboxypyridine
Acide Nicotinique
Acido nicotinico
Acidum Nicotinicum
Akotin
Anti-pellagra vitamin
Apelagrin
Daskil
Efacin
Enduracin
Linic
M-Pyridinecarboxylic Acid
Niac
Niacin
Niacine
Niacor
Nicacid
Nicamin
Nicangin
 
Nico-Span
Nicobid
Nicocap
Nicodelmine
Nicolar
Niconacid
Nicosan 3
Nicotinate
Nicotinic Acid
Nicotinic acid
Nicotinipca
Nicyl
Nikotinsaeure
Nyclin
P.P. factor
PP Factor
Pellagra preventive factor
Pellagrin
Pelonin
Pyridine-beta-carboxylic acid
Slo-niacin
Vitamin B3
Wampocap
beta-Pyridinecarboxylic acid
pyridine-β-carboxylic acid
β-pyridinecarboxylic acid

Interventional clinical trials:

(show all 43)
idNameStatusNCT IDPhase
1The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck CancerUnknown statusNCT01845922Phase 4
2A Study Comparing the Iron Substitution With the Medicinal Products Ferinject or MonoferRecruitingNCT02905539Phase 4
3Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic RicketsCompletedNCT00417612Phase 3
4Treatment of Autonomous Hyperparathyroidism in Post Renal Transplant RecipientsCompletedNCT00975000Phase 3
5Therapeutic Use of Oral Sodium Phosphate (Z-521) in Primary Hypophosphatemic RicketsCompletedNCT01237288Phase 3
6Efficacy and Safety of KRN23 Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With X Linked Hypophosphatemia (XLH)RecruitingNCT02915705Phase 3
7Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)Active, not recruitingNCT02526160Phase 3
8Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)Active, not recruitingNCT02537431Phase 3
9Hypophosphatemia With Intravenous Ferric Carboxymaltose Versus Iron Dextran in Women With Iron Deficiency Secondary to Heavy Uterine BleedingUnknown statusNCT01307007Phase 2
10Investigating a New Way of Giving Medicine to Newborn and Preterm BabiesUnknown statusNCT01676844Phase 2
11An Extension Study of KRN23 in Adults With X-Linked HypophosphatemiaCompletedNCT01571596Phase 1, Phase 2
12A Repeated Study of KRN23 in Adults With X-Linked HypophosphatemiaCompletedNCT01340482Phase 1, Phase 2
13Extended Safety Study of Tenofovir Disoproxil Fumarate (TDF) Among HIV-1 Negative MenCompletedNCT00131677Phase 2
14Cetuximab and Lenalidomide in Head and NeckCompletedNCT01133665Phase 2
15Growth Hormone Treatment in Children With Hypophosphatemic RicketsCompletedNCT02720770Phase 1, Phase 2
16Role Of Phosphorus And FGF 23 In Patients With Dent DiseaseRecruitingNCT02016235Phase 1, Phase 2
17Study of KRN23, a Recombinant Fully Human Monoclonal Antibody Against FGF23, in Pediatric Subjects With X-linked Hypophosphatemia (XLH)Active, not recruitingNCT02163577Phase 2
18Study of the Safety, Pharmacodynamics and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)Active, not recruitingNCT02750618Phase 2
19Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)Enrolling by invitationNCT02312687Phase 2
20Effects of GH on Body Proportions and Final Height in X-Linked Hypophosphatemic RicketsUnknown statusNCT00473187Phase 1
21Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic RicketsUnknown statusNCT00195936Phase 1
22A Study of KRN23 in X-linked HypophosphatemiaCompletedNCT00830674Phase 1
23Multiple Dose Study to Evaluate the Safety of Multiple Doses of Denosumab 120 mg in Adults With Severe Chronic Kidney Disease (CKD) and CKD on DialysisCompletedNCT01464931Phase 1
24A Study of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/OsteomalaciaCompletedNCT02181764Phase 1
25Mechanistic Evaluation on Sorafenib Induced Hypophosphatemia.TerminatedNCT00622479Phase 1
26Cinacalcet for Fibroblast Growth Factor 23 (FGF23)-Mediated Hypophosphatemia (Hypophosphatemic Rickets)TerminatedNCT01748812Phase 1
27Using Cinacalcet to Treat the Hypophosphatemia of Early Kidney TransplantUnknown statusNCT01011114
28Perspective Evaluation of Hormones Involved in Serum Phosphate Homeostasis in Patients With Metastatic Renal Cells Carcinoma or Hepatocellular Carcinoma Treated With Sorafenib (SORHORM)Unknown statusNCT01230697
29Calcimimetics in Hypophosphatemic RicketsUnknown statusNCT00844740
30Calcitonin for Treating X-linked HypophosphatemiaCompletedNCT01652573
31FGF-23 Suppressibility by CalcitoninCompletedNCT00688077
32Does Intravenous Iron Therapy Decrease Serum Phosphorous Levels?CompletedNCT02420119
33A Prospective Cohort Study to Describe the Evolution of Persistent Hyperparathyroidism in Kidney Transplant RecipientsCompletedNCT01163669
34Effect of the Consumption of Ferric Hydroxide Adipate on Urinary Phosphorus Excretion.CompletedNCT01991574Early Phase 1
35Effect of Dietary Protein Source on Phosphaturia, PTH and FGF23 in Patients With CKD 3 and 4CompletedNCT00764816
36Leptin, IGF1 and the Refeeding IndexCompletedNCT01227850
37Studying Phosphorus MetabolismCompletedNCT00066183
38Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic OsteomalaciaCompletedNCT00099762
39Assessment Of Vitamin D Role In The Pathogenesis Of Asthma In Vitamin D Resistent PatientsCompletedNCT01578824
40Observing the Changes of Fibroblast Growth Factor 23 in Patients of Tumor Induced OsteomalaciaRecruitingNCT01660308
41Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.RecruitingNCT02233322
42Serum Calcium to Phosphorous Ratio (Ca/P) as a Simple, Inexpensive Screening Tool in the Diagnosis of Primary HyperparathyroidismRecruitingNCT03027349
43Hypophosphatemic Rickets in NorwayActive, not recruitingNCT01057186

Search NIH Clinical Center for Hypophosphatemia

Inferred drug relations via UMLS67/NDF-RT45:

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Genetic Tests for Hypophosphatemia

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Genetic tests related to Hypophosphatemia:

id Genetic test Affiliating Genes
1 Hypophosphatemia26

Anatomical Context for Hypophosphatemia

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MalaCards organs/tissues related to Hypophosphatemia:

35
Kidney, Bone, Liver, Skeletal muscle, Prostate, Myeloid, Brain

Animal Models for Hypophosphatemia or affiliated genes

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MGI Mouse Phenotypes related to Hypophosphatemia:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.2CLCN5, DMP1, ENPP1, FGF23, PHEX, SFRP4
2MP:00053787.9CLCN5, DMP1, ENPP1, FGF23, PHEX, PTH
3MP:00053767.9CLCN5, DMP1, ENPP1, FGF23, PHEX, PTH
4MP:00053906.6CLCN5, DMP1, ENPP1, FGF23, MEPE, PHEX

Publications for Hypophosphatemia

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Articles related to Hypophosphatemia:

(show top 50)    (show all 596)
idTitleAuthorsYear
1
Corn-Soy-Blend Fortified with Phosphorus to Prevent Refeeding Hypophosphatemia in Undernourished Piglets. (28081252)
2017
2
Two Case Reports of FGF23-Induced Hypophosphatemia in Childhood Biliary Atresia. (27462066)
2016
3
Incidence of hypophosphatemia in advanced cancer patients: a recent report from a single institution. (27832387)
2016
4
An Institutional Change in Continuous Renal Replacement Therapy: Nutrition Support Team Resolves Resultant Severe Hypophosphatemia. (27589256)
2016
5
Hypophosphatemia and recovery of post-hepatectomy liver insufficiency. (27275463)
2016
6
Whole exome sequencing confirms the clinical diagnosis of Marfan syndrome combined with X-linked hypophosphatemia. (26040324)
2015
7
Hypophosphatemia and sudden infant death syndrome (SIDS)-is ATP the link? (24151935)
2013
8
Spurious hypophosphatemia associated with monoclonal paraproteinemia. (21719426)
2012
9
Hemolytic anemia associated with severe hypophosphatemia in a renal transplant recipient. (22117608)
2012
10
Calcitonin administration in X-linked hypophosphatemia. (21524226)
2011
11
Hypophosphatemia: an evidence-based problem-solving approach to clinical cases. (20622306)
2010
12
Hypophosphatemia-induced seizure in a child with diabetic ketoacidosis. (20016359)
2009
13
Is this the worst outcome of metabolic syndrome? Hypophosphatemia and resulting cardiac arrest during the treatment of diabetic ketoacidosis with hypertriglyceridemia. (19687585)
2009
14
Dialysis: preventing hypophosphatemia during pediatric CRRT. (19384323)
2009
15
Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia. (19555782)
2009
16
Hypophosphatemia as unusual cause of ARDS in Cushing's syndrome secondary to ectopic CRH production. A case report. (18264630)
2008
17
Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia. (18305465)
2008
18
Hypophosphatemia and neuroleptic malignant syndrome. (17502779)
2007
19
Acquired hypophosphatemia osteomalacia associated with Fanconi's syndrome in SjAPgren's syndrome. (17094001)
2007
20
Post-transplant hypophosphatemia: Tertiary 'Hyper-Phosphatoninism'? (16941023)
2006
21
X-linked hypophosphatemia: dental and histologic findings. (16480608)
2006
22
Hypophosphatemia and calcium nephrolithiasis. (15499207)
2004
23
Is hypotonic dysfunctional labor associated with hypophosphatemia? (15167865)
2004
24
Down-regulation of Na+ transporters and AQP2 is responsible for acyclovir-induced polyuria and hypophosphatemia. (14675048)
2004
25
New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice. (15029877)
2004
26
Hypophosphatemia after 95 right-lobe living-donor hepatectomies for liver transplantation is not a significant source of morbidity. (14557757)
2003
27
Intravenous phosphate in the intensive care unit: more aggressive repletion regimens for moderate and severe hypophosphatemia. (12845429)
2003
28
Hypophosphatemia associated with hypovitaminosis-D in Speke's gazelles (Gazella spekei). (12785689)
2001
29
Propranolol rapidly reverses paralysis, hypokalemia, and hypophosphatemia in thyrotoxic periodic paralysis. (11228188)
2001
30
Hypophosphatemia and hypomagnesemia induced by cooling in patients with severe head injury. (11354399)
2001
31
Hypophosphatemia in the emergency department therapeutics. (10919539)
2000
32
Management of hypophosphatemia induced by high-flux hemodiafiltration for the treatment of vancomycin toxicity: intravenous phosphorus therapy versus use of a phosphorus-enriched dialysate. (11096051)
2000
33
Effect of donor age and rejection episodes on hypophosphatemia in long-term kidney transplant patients. (11119994)
2000
34
Evidence for Phex haploinsufficiency in murine X-linked hypophosphatemia. (10087298)
1999
35
The clinical implications of hypophosphatemia following major hepatic resection or cryosurgery. (9688005)
1998
36
Hemodynamic and metabolic effects of rapid correction of hypophosphatemia in patients with septic shock. (7781370)
1995
37
Osteomalacia with hypophosphatemia and hypercalciuria: a possible new variant of osteomalacia. (7608793)
1995
38
Nephrocalcinosis in X-linked hypophosphatemia: effect of treatment versus disease. (7794712)
1995
39
Severe unexplained hypophosphatemia. (1733579)
1992
40
Chronic metabolic acidosis increases the serum concentration of 1,25-dihydroxyvitamin D in humans by stimulating its production rate. Critical role of acidosis-induced renal hypophosphatemia. (1469097)
1992
41
Does hypophosphatemia play a role in acute liver failure? (2921001)
1989
42
Severity of postoperative hypophosphatemia in relation to glucose administration and renal handling of phosphate. (3232477)
1988
43
Reversible depression of myocardial performance in hypophosphatemia. (3354591)
1988
44
Hypophosphatemia-associated respiratory muscle weakness in a general inpatient population. (3364446)
1988
45
Blood gas changes and hypophosphatemia in lactate-induced panic. (3122697)
1988
46
Effect of hypophosphatemia on diaphragmatic contractility in patients with acute respiratory failure. (3860734)
1985
47
Potentially life-threatening hypophosphatemia in anorexia nervosa. (6841239)
1983
48
The defect in transcellular transport of phosphate in the nephron is located in brush-border membranes in X-linked hypophosphatemia (Hyp mouse model). (566613)
1978
49
Occurrence of hyperparathyroidism in children with X-linked hypophosphatemia under treatment with vitamin D and phsophate. (899930)
1977
50
Familial forms of vitamin D-resistant rickets revisited. X-linked hypophosphatemia and autosomal recessive vitamin D dependency. (187056)
1976

Variations for Hypophosphatemia

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Expression for genes affiliated with Hypophosphatemia

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Search GEO for disease gene expression data for Hypophosphatemia.

Pathways for genes affiliated with Hypophosphatemia

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GO Terms for genes affiliated with Hypophosphatemia

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Biological processes related to Hypophosphatemia according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1cellular response to parathyroid hormone stimulusGO:007137410.4FGF23, SLC34A1
2phosphate ion transportGO:000681710.4SLC34A1, SLC34A3
3sodium-dependent phosphate transportGO:004434110.4SLC34A1, SLC34A3
4phosphate ion transmembrane transportGO:003543510.4SLC34A1, SLC34A3
5phosphate-containing compound metabolic processGO:000679610.3ENPP1, FGF23
6response to parathyroid hormoneGO:007110710.2PTH, SLC34A1
7cellular response to vitamin DGO:007130510.2BGLAP, FGF23
8response to cadmium ionGO:004668610.1PTH, SLC34A1
9phosphate ion homeostasisGO:005506210.1FGF23, SFRP4, SLC34A1
10bone mineralizationGO:003028210.0BGLAP, PHEX
11negative regulation of bone mineralizationGO:00305029.9FGF23, MEPE
12response to magnesium ionGO:00320269.8FGF23, SLC34A1, SLC34A3
13response to vitamin DGO:00332809.8BGLAP, PTH
14cellular phosphate ion homeostasisGO:00306439.6ENPP1, FGF23, SLC34A1, SLC34A3
15regulation of bone mineralizationGO:00305009.5BGLAP, ENPP1, FGF23
16response to lead ionGO:00102889.5PTH, SLC34A1
17response to nutrient levelsGO:00316679.2BGLAP, PTH, SLC34A3
18ossificationGO:00015038.9BGLAP, DMP1, DSPP, SLC34A1
19biomineral tissue developmentGO:00312148.5DMP1, DSPP, ENPP1, MEPE
20skeletal system developmentGO:00015017.8BGLAP, DSPP, MEPE, PHEX, PTH

Molecular functions related to Hypophosphatemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sodium:phosphate symporter activityGO:00054369.8SLC34A1, SLC34A3
2inorganic phosphate transmembrane transporter activityGO:00053159.7SLC34A1, SLC34A3
3sodium-dependent phosphate transmembrane transporter activityGO:00153219.5SLC34A1, SLC34A3

Sources for Hypophosphatemia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet