MCID: HYP083
MIFTS: 52

Hypopituitarism malady

Categories: Genetic diseases, Rare diseases, Endocrine diseases

Aliases & Classifications for Hypopituitarism

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Aliases & Descriptions for Hypopituitarism:

Name: Hypopituitarism 11 47 26 49 38 13 67
Pituitary Insufficiency 11 47
 
Pituitary Hormone Deficiency 11
Pituitary Hypofunction 11

Classifications:



External Ids:

Disease Ontology11 DOID:9406
ICD1029 E23.0, E23
MeSH38 D007018
NCIt44 C62591

Summaries for Hypopituitarism

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Disease Ontology:11 A pituitary gland disease characterized by the decreased secretion of one or more of the eight hormones normally produced by the pituitary gland.

MalaCards based summary: Hypopituitarism, also known as pituitary insufficiency, is related to lactic acidosis and candidiasis. An important gene associated with Hypopituitarism is PROP1 (PROP Paired-Like Homeobox 1), and among its related pathways are Growth hormone receptor signaling and Glucocorticoid receptor regulatory network. Affiliated tissues include pituitary, brain and testes, and related mouse phenotypes are hearing/vestibular/ear and mortality/aging.

Wikipedia:70 Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced... more...

Related Diseases for Hypopituitarism

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Diseases in the Hypopituitarism family:

Familial Hypopituitarism

Diseases related to Hypopituitarism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 297)
idRelated DiseaseScoreTop Affiliating Genes
1lactic acidosis29.7POMC, PRL
2candidiasis28.8INS, POMC, PRL
3obesity27.8GHRH, IGF1, INS, POMC, PRL
4craniopharyngioma27.6GH1, GHRH, INS, POMC, PRL
5diabetes insipidus25.2GHRH, GLI2, HESX1, IGF1, INS, LHX3
6pituitary hormone deficiency, combined, 312.4
7pituitary hormone deficiency, combined, 112.4
8choroideremia hypopituitarism11.9
9anterior pituitary insufficiency, familial11.9
10familial hypopituitarism11.9
11corpus callosum dysgenesis hypopituitarism11.7
12distal arthrogryposis with hypopituitarism, intellectual disability and facial anomalies11.7
13hypopituitarism postaxial polydactyly11.7
14sheehan syndrome11.4
15combined pituitary hormone deficiencies, genetic forms11.2
16pallister-hall syndrome11.2
17septooptic dysplasia11.1
18combined pituitary hormone deficiency11.1
19lymphocytic hypophysitis11.1
20pituitary deficiency due to empty sella turcica syndrome11.1
21rhyns syndrome10.9
22holoprosencephaly-910.8
23culler-jones syndrome10.8
24laurence-moon syndrome10.8
25stiff-person syndrome10.8
26septo-optic dysplasia spectrum10.7
27microvascular complications of diabetes 310.5GH1, POU1F1
28growth hormone insensitivity, partial10.5GH1, IGF1
29polydactyly, preaxial, type iv10.4GLI2, IGF1
30olecranon bursitis10.4LHX3, PROP1
31seizures mental retardation hair dysplasia10.4IGF1, INS
32autoimmune oophoritis10.3GH1, POMC
33thbd-related atypical hemolytic-uremic syndrome10.3IGF1, INS
34diarrhea 3, secretory sodium, congenital, syndromic10.3IGF1, INS
35brain injury10.3
36multiple mitochondrial dysfunctions syndrome10.3IGF1, POMC
37fetal methyl mercury syndrome10.3IGF1, INS
38traumatic brain injury10.3
39fumarate hydratase deficiency10.3GH1, PRL
40ovarian mucinous malignant adenofibroma10.3GH1, PRL
41fibrosclerosis of breast10.3IGF1, PRL
42hyperinsulinemic hypoglycemia, familial, 510.2IGF1, INS
43splenic artery aneurysm10.2IGF1, INS
44aromatase excess syndrome10.2GH1, INS
45isolated growth hormone deficiency10.2
46peritoneal benign neoplasm10.2IGF1, POMC
47benign eccrine breast spiradenoma10.2INS, POMC
48diencephalic neoplasm10.1IGF1, INS, POU1F1
49corpus luteum cyst10.1IGF1, POMC
50signet ring cell adenocarcinoma10.1GH1, IGF1, INS

Graphical network of the top 20 diseases related to Hypopituitarism:



Diseases related to hypopituitarism

Symptoms for Hypopituitarism

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Drugs & Therapeutics for Hypopituitarism

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Drugs for Hypopituitarism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 127)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CosyntropinapprovedPhase 42416960-16-016129617
Synonyms:
16960-16-0
ATCH (1-24)
Adrenocorticotropic hormone fragment 1-24 human, rat
COSYNTROPIN
Corticotropin tetracosapeptide
Cortrosyn
Cortrosyn (TN)
Cosyntropin
Cosyntropin (USAN)
 
D00284
Tetracosactide
Tetracosactide (INN)
Tetracosactrin
adrenocorticotropic hormone 1-24
alpha(1-24)-corticotrophin
beta(1-24)-corticotrophin
corticotropin-(1-24)
corticotropin-(1-24) tetracosapeptide
α1-24-corticotrophin
β1-24-corticotrophin
2
MethyltestosteroneapprovedPhase 4, Phase 254658-18-46010
Synonyms:
17(alpha)-Methyl-delta(4)-androsten-17(beta)-ol-3-one
17-Methyltestosterone
17-beta-Hydroxy-17-methylandrost-4-en-3-one
17-methyltestosterone
17alpha-Methyl-3-oxo-4-androsten-17beta-ol
17alpha-Methyl-delta(4)-androsten-17beta-ol-3-one
17alpha-Methyltestosterone
17alpha-methyl-delta-androsten-17beta-ol-3-one
17alpha-methyltestosterone
 
17beta-Hydroxy-17-methylandrost-4-en-3-one
17α-methyl-Δ4-androsten-17β-ol-3-one
17α-methyltestosterone
4-Androstene-17alpha-methyl-17beta-ol-3-one
Android
Methyltestosterone
Methyltestosteronum
Metiltestosterona
NSC-9701
Testred
Virilon
3
Testosteroneapproved, investigationalPhase 4, Phase 254658-22-06013
Synonyms:
(+)-testosterone
(+-)-8-iso-testosterone
(+-)-retrotestosterone
(+-)-testosterone
(17b)-17-hydroxy-androst-4-en-3-one
(17beta)-17-Hydroxyandrost-4-en-3-one
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
13-Iso-testosterone
17-Hydroxy-(17-beta)-androst-4-en-3-one
17-Hydroxy-(17beta)-androst-4-en-3-one
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
17-Hydroxy-D4-androsten-3-one
17-Hydroxy-androst-4-en-3-one
17-beta-Hydroxy-delta(sup 4)-androsten-3-one
17-beta-Hydroxyandrost-4-en-3-one
17?-Hydroxy-4-androsten-3-one
17a-Hydroxy-(13a)-androst-4-en-3-one
17a-Hydroxy-13a-androst-4-en-3-one
17a-Hydroxy-14b-androst-4-en-3-one
17a-Hydroxy-androst-4-en-3-one
17b-Hydroxy-(10a)-androst-4-en-3-one
17b-Hydroxy-(13a)-androst-4-en-3-one
17b-Hydroxy-(8a)-androst-4-en-3-one
17b-Hydroxy-(8a,10a)-androst-4-en-3-one
17b-Hydroxy-(9b)-androst-4-en-3-one
17b-Hydroxy-(9b,10a)-androst-4-en-3-one
17b-Hydroxy-13a-androst-4-en-3-one
17b-Hydroxy-8a-androst-4-en-3-one
17b-Hydroxy-D4-androsten-3-one
17b-Hydroxy-androst-4-en-3-on
17b-Hydroxy-androst-4-en-3-one
17b-Hydroxyandrost-4-en-3-one
17b-Hydroxyandrost-4-ene-3-one
17b-Testosterone
17b-hydroxy-4-androsten-3-one
17beta-Hydroxy-3-oxo-4-androstene
17beta-Hydroxy-4-androsten-3-one
17beta-Hydroxy-delta(sup4)-androsten-3-one
17beta-Hydroxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-ene-3-one
17beta-hydroxy-4-androsten-3-one
4-Androsten-17?-ol-3-one
4-Androsten-17beta-ol-3-one
4-Androsten-3-one-17b-ol
4-androsten-17β-ol-3-one
4-androstene-17beta-ol-3-one
46923_FLUKA
46923_RIEDEL
58-22-0
7-beta-Hydroxyandrost-4-en-3-one
8-Iso-testosterone
9b,10a-Testosterone
9b-Testosterone
AA 2500
AC-14899
AC1L1LM0
Andriol
Andro
Andro 100
Andro L.A. 200
AndroGel
Androderm
Androderm (TN)
Androgel
Androgel (TN)
Android 10
Android 25
Android 5
Androlin
Andronaq
Andronate 100
Andronate 200
Andropatch
Andropository 200
Androsorb
Androst-4-en-17b-ol-3-one
Androst-4-en-17beta-ol-3-one
Androst-4-ene-17b-ol-3-one
Andrusol
Andryl 200
B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E
BIDD:ER0555
BIM-0061761.0001
Beta Testosterone
Bio-0678
Bio-T-Gel
C00535
CCRIS 574
CDB 111C
CHEBI:17347
CHEMBL386630
CID6013
CMC_13449
COL 1621
CP 601B
CPD000058344
Cristerona T
Cristerone T
D00075
D4-Androsten-17b-ol-3-one
DB00624
Dea No. 4000
Delatest
Delatestryl
Depo-Testadiol
Depo-Testosterone
Depo-Testosterone Cypionate
Depotest
EINECS 200-370-5
Epitestosteron
Everone 200
Geno-Cristaux Gremy
Geno-cristaux Gremy
Geno-cristaux gremy
HMS2052N11
HSDB 3398
Halotensin
Homosteron
Homosterone
 
Intrinsa
LMST02020002
LS-148813
LibiGel
Libigel
Lumitestosteron
MLS000563091
MLS001032098
MLS001306401
MLS002174283
Malerone
Malestrone
Malestrone (amps)
Malogen in Oil
Malogen, Aquaspension Injection
Malogen, aquaspension injection
Mertestate
Metandren
Methyltestosterone
MolPort-002-506-901
NCGC00091018-01
NSC 9700
Neo-Hombreol F
Neo-Testis
Neo-testis
Neotestis
Oreton
Oreton F
Oreton Methyl
Oreton-F
Orquisteron
Perandren
Percutacrine Androgenique
Percutacrine androgenique
Primotest
Primoteston
Rac-17b-hydroxy-(13a)androst-4-en-3-one
Rac-17b-hydroxy-(8a)-androst-4-en-3-one
Rac-17b-hydroxy-(9b,10a)androst-4-en-3-one
Rac-17b-hydroxy-androst-4-en-3-one
Relibra
Retrotestosterone
S00309
S2033_Selleck
SAM001246921
SMR000058344
SMR001261453
Scheinpharm Testone-Cyp
Striant
Striant (TN)
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
T1500_SIGMA
T5411_FLUKA
T5411_SIGMA
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testiculosterone
Testim
Testim (TN)
Testobase
Testoderm
Testoderm Tts
Testogel
Testoject-50
Testolent
Testolin
Testopel Pellets
Testopropon
Testosteroid
Testosteron
Testosterona
Testosterona [INN-Spanish]
Testosterone
Testosterone (JAN/USP)
Testosterone Cypionate
Testosterone Enanthate
Testosterone Hydrate
Testosterone [Androgenic steroids, anabolic]
Testosterone [INN:BAN]
Testosterone and its esters
Testosterone hydrate
Testosterone solution
Testosteronum
Testosteronum [INN-Latin]
Testostosterone
Testostérone
Testoviron
Testoviron Schering
Testoviron T
Testoxyl
Testred
Testred Cypionate 200
Testrin-P.A
Testro AQ
Testro Aq
Testrone
Testryl
Tostrelle
Tostrex
Trans-Testosterone
UNII-3XMK78S47O
Viatrel
Virilon
Virilon IM
Virormone
Virosterone
ZINC06500184
beta testosterone
delta(sup 4)-Androsten-17(beta)-ol-3-one
delta4-Androsten-17beta-ol-3-one
delta4-androsten-17b-ol-3-one
testosterone
trans-Testosterone
4
Hydrocortisoneapproved, vet_approvedPhase 4, Phase 3, Phase 2, Early Phase 164050-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
5
Epinephrineapproved, vet_approvedPhase 4, Phase 3, Phase 293351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
6Epinephryl boratePhase 4, Phase 3, Phase 2933
7Hydrocortisone 17-butyrate 21-propionatePhase 4, Phase 3, Phase 2, Early Phase 1640
8RacepinephrinePhase 4, Phase 3, Phase 2933
9Anabolic AgentsPhase 4, Phase 2499
10MitogensPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 11526
11Insulin, Globin ZincPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 14523
12insulinPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 14524
13Hydrocortisone acetatePhase 4, Phase 3, Phase 2, Early Phase 1640
14HormonesPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 113979
15Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 112778
16Antineoplastic Agents, HormonalPhase 4, Phase 2, Phase 35407
17Cortisol succinatePhase 4, Phase 3, Phase 2, Early Phase 1640
18Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 112767
19AndrogensPhase 4, Phase 2, Phase 31275
20Anti-Inflammatory AgentsPhase 4, Early Phase 110355
21
Testosterone enanthatePhase 4, Phase 2546315-37-79416
Synonyms:
17-((1-Oxoheptyl)oxy)androst-4-en-3-one
17-Hydroxyandrost-4-en-3-one, 17-heptanoate
17-Hydroxyandrost-4-en-3-one, 17-heptanoic acid
17beta-Enanthoxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-en-3-one enanthate
4-Androsten-17beta-ol-3-one 17-enanthate
4-Androsten-3-one 17beta-enanthate
Androgyn L.A.
Andropository
Androtardyl
Atlatest
DEA No. 4000
DePatestrye
Delatest
Delatestryl
Depo-Testro Med
Ditate
Durathate
Everone
 
Exten test
Malogen L.A.
Malogen L.A.200
Orquisteron-E
Primotestone
Reposo TMD
Testanthate
Testate
Testenate
Testinon
Testoenant
Testonenant
Testosterone 17-enanthate
Testosterone 17beta-heptanoate
Testosterone 17beta-heptanoic acid
Testosterone enantate
Testosterone heptoate
Testosterone heptoic acid
Testosterone heptylate
Testosterone oenanthate
Testostroval
22Testosterone undecanoatePhase 4, Phase 2546
23Testosterone 17 beta-cypionatePhase 4, Phase 2546
24Pharmaceutical SolutionsPhase 4, Phase 3, Phase 27793
25
ZincapprovedPhase 3, Early Phase 122317440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
26
BenzocaineapprovedPhase 318921994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
27
ClonidineapprovedPhase 32264205-90-72803
Synonyms:
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI)
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2,6-dichloro-N-(2-imidazolidinylidene)aniline
2,6-dichloro-N-2-imidazolidinylidenebenzenamide
2,6-dichloro-N-imidazolidin-2-ylideneaniline
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
2-(2,6-Dichlorophenylimino)imidazolidine
2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI)
2-[(2,6-Dichlorophenyl)imino]imidazoline
2-[(2,6-dichlorophenyl)imino]-2-imidazoline
4205-90-7
4205-91-8 (mono-hydrochloride)
57066-25-8
734571A
AB00514634
AC1L1EI5
AC1Q3K6V
AKOS001595470
Adesipress
BIDD:GT0547
BPBio1_000040
BRD-K98530306-001-02-1
BRD-K98530306-003-05-0
BSPBio_000036
BSPBio_001588
BSPBio_002055
Bio1_000470
Bio1_000959
Bio1_001448
Bio2_000308
Bio2_000788
C9H9Cl2N3
CAS-4205-91-8
CATAPRES-TTS-1
CATAPRES-TTS-2
CATAPRES-TTS-3
CCRIS 7787
CHEBI:3757
CHEBI:46632
CHEMBL134
CID2803
Catapres
Catapres- TTS
Catapres-TTS
Catapresan
Catapressan
Catarpres
Catarpres-TTS
Catarpres-TTS (TN)
Catarpresan
Chlofazoline
Chlornidinum
Clofenil
Clonidin
Clonidina
Clonidina [INN-Spanish]
Clonidine (JAN/USAN/INN)
Clonidine HCl
Clonidine [USAN:BAN:INN]
Clonidinhydrochlorid
Clonidinum
Clonidinum [INN-Latin]
Clonistada
Clopheline
D00281
DB00575
DB07566
DivK1c_000774
 
Dixarit
Duraclon
Duraclont
EINECS 224-119-4
Gemiton
HMS1361P10
HMS1791P10
HMS1989P10
HMS2089G11
HSDB 3040
Hemiton
IDI1_000774
IDI1_034058
Ipotensium
Isoglaucon
KBio1_000774
KBio2_000308
KBio2_001821
KBio2_002876
KBio2_004389
KBio2_005444
KBio2_006957
KBio3_000615
KBio3_000616
KBio3_001275
KBioGR_000308
KBioGR_001572
KBioSS_000308
KBioSS_001821
Klofelin
Klofenil
L000193
LS-79606
Lopac-C-7897
Lopac0_000268
M 5041T
M-5041T
MolPort-001-779-668
MolPort-005-932-374
N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
NCGC00015268-01
NCGC00015268-02
NCGC00015268-08
NCGC00024734-01
NCGC00024734-02
NCGC00024734-03
NCGC00024734-04
NCGC00024734-05
NCGC00179680-01
NINDS_000774
Prestwick0_000248
Prestwick1_000248
Prestwick2_000248
Prestwick3_000248
SKF 34427
SPBio_001233
SPBio_002255
ST 155BS
ST-155-BS
ST-155BS
Spectrum2_001187
Spectrum3_000358
Spectrum4_000956
Spectrum5_000759
Spectrum_001341
T171
Tenso-Timelets
Tocris-0690
UNII-MN3L5RMN02
ZINC00896484
clonidine
nchembio.79-comp11
nchembio705-10
28
Anastrozoleapproved, investigationalPhase 2, Phase 3272120511-73-12187
Synonyms:
.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
120511-73-1
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
AC-4234
AC1L1D49
Anastrazole
Anastrole
Anastrozol
Anastrozole (JAN/USAN/INN)
Anastrozole [USAN:INN:BAN]
Arimidex
Arimidex (TN)
Arimidex (Zeneca)
Arimidex, Anastrozole
Asiolex
Astra brand of anastrozole
AstraZeneca brand of anastrozole
C08159
C090450
C17H19N5
CHEBI:2704
CHEMBL1399
CID2187
CPD000466301
 
D00960
DB01217
HMS2052M11
HMS2089N10
HSDB 7462
I06-0021
ICI D1033
ICI-D 1033
ICI-D1033
LS-29563
MLS000759396
MLS001424217
MolPort-005-933-078
NCGC00164619-01
NSC719344
S1188_Selleck
SAM001246525
SBB066057
SMR000466301
UNII-2Z07MYW1AZ
ZD 1033
ZD-1033
ZD1033
ZINC00000941
Zeneca ZD 1033
Zeneca brand of anastrozole
alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
anastrazole
anastrozole
29
Lidocaineapproved, vet_approvedPhase 2, Phase 31226137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
30tannic acidapproved, NutraceuticalPhase 31892
31Hypoglycemic AgentsPhase 3, Early Phase 15733
32AnestheticsPhase 2, Phase 39001
33Neurotransmitter AgentsPhase 3, Phase 217734
34Autonomic AgentsPhase 3, Phase 29774
35Respiratory System AgentsPhase 2, Phase 34818
36Antihypertensive AgentsPhase 34095
37SympatholyticsPhase 3555
38Peripheral Nervous System AgentsPhase 3, Phase 222776
39Adrenergic alpha-AgonistsPhase 3, Phase 21625
40Steroid Synthesis InhibitorsPhase 2, Phase 31718
41AntibodiesPhase 3, Phase 26045
42AnalgesicsPhase 3, Phase 211287
43Estrogen AntagonistsPhase 2, Phase 31315
44Aromatase InhibitorsPhase 2, Phase 3807
45ImmunoglobulinsPhase 3, Phase 26045
46EstrogensPhase 2, Phase 32470
47Adrenergic AgentsPhase 3, Phase 25140
48Adrenergic AgonistsPhase 3, Phase 22877
49Adrenergic alpha-2 Receptor AgonistsPhase 3911
50Growth Hormone-Releasing HormonePhase 3, Phase 2, Phase 128

Interventional clinical trials:

(show top 50)    (show all 220)
idNameStatusNCT IDPhase
1Baseline Sexual Function, Cognitive Function, Body Composition and Muscle Parameters and Pharmacokinetics of Transdermal Testosterone Gel in Women With HypopituitarismUnknown statusNCT00144404Phase 4
2Testosterone Gel Applied to Women With Pituitary Gland ProblemsUnknown statusNCT00144391Phase 4
3Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen TestUnknown statusNCT00851942Phase 4
4Comparison of Two Growth Hormone Dosing Methods in Adults With Growth Hormone DeficiencyCompletedNCT00490191Phase 4
5Effect of 5 Years of GH Replacement on AtherosclerosisCompletedNCT00462475Phase 4
6Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve HypoplasiaCompletedNCT00140413Phase 4
7Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine SupplementationCompletedNCT00360074Phase 4
8A Multicentre, Randomised, Open-label, Controlled Study to Evaluate the Effects of Saizen® on Cardiac Function in Growth Hormone Deficient(GHD) Subjects During the Transition Phase From Childhood to AdulthoodCompletedNCT01157793Phase 4
9Growth Hormone and Endothelial Function in ChildrenCompletedNCT00373386Phase 4
10Bone Mineral Density (BMD) in Adolescents With Growth Hormone Deficiency (GHD)CompletedNCT00097526Phase 4
11An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)CompletedNCT01806298Phase 4
12Safety and Efficacy of SR-hGH (Sustained-release Human Growth Hormone, Declage Inj.)CompletedNCT01605331Phase 4
13Effect of Somatropin on Left Ventricular Mass in Growth Hormone Deficient Adult PatientsCompletedNCT01562834Phase 4
14Comparison of a Needle-free Injection Method With a Needle-syringe Injection MethodCompletedNCT00990340Phase 4
15Growth Hormone and Glucose MetabolismCompletedNCT00929799Phase 4
16Easypod United States User TrialCompletedNCT00689260Phase 4
17Liquid Somatropin Formulation in Children With Growth Hormone DeficiencyCompletedNCT00567385Phase 4
18A Post Marketing Surveillance Study for NutropinAq® in Adults With Growth Hormone DeficiencyCompletedNCT00455884Phase 4
19Predictive Markers in GHD and TS Children Treated With SAIZEN®CompletedNCT00256126Phase 4
20IGF1 Generation TestCompletedNCT00145457Phase 4
21GH and Cardiovascular Risk FactorsCompletedNCT01877512Phase 4
22First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation StudyCompletedNCT01419249Phase 4
23Is There a Sensibility Increased in the Growth Hormone at Child With Prader-Willi Syndrome?CompletedNCT01298180Phase 4
24Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or ParentsCompletedNCT01245374Phase 4
25Predictive Markers in Chinese Growth Hormone Deficiency (GHD) Children Treated With Saizen®CompletedNCT01187550Phase 4
26Anterior Pituitary Hormone Replacement in Traumatic Brain InjuryCompletedNCT00957671Phase 4
27A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in BloodCompletedNCT00212758Phase 4
28National Cooperative Growth Study (NCGS) of Optimal Nutropin AQ and Nutropin Dosing in Pubertal Growth Hormone-Deficient (GHD) PatientsCompletedNCT00097513Phase 4
29Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone DeficiencyRecruitingNCT02976675Phase 4
30Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone DeficiencyRecruitingNCT02908958Phase 4
31Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children (Clinical Trial I)RecruitingNCT02380235Phase 4
32A Post-Marketing Open-Label Study of the Efficacy and Immunogenicity of Somatropin (Ribosomal Deoxyribonucleic Acid [rDNA] Origin) (Nutropin AQ®) in Children With Growth Hormone DeficiencyRecruitingNCT02311894Phase 4
33Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.RecruitingNCT03015909Phase 4
34Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency ChildrenRecruitingNCT02314676Phase 4
35Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone DeficiencyTerminatedNCT01698944Phase 4
36A Study to Evaluate the Efficacy of Somatropin in Adults With Growth Hormone Deficiency Caused by Trauma and/or Head InjuryTerminatedNCT00638053Phase 4
37Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain InjuryTerminatedNCT00555009Phase 4
38Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain Injury.WithdrawnNCT00432263Phase 4
39Treatment of Children With Insufficient Secretion of Growth HormoneUnknown statusNCT00271518Phase 3
40Arimidex Multicenter Trial in Growth Hormone (GH) Deficient BoysCompletedNCT00133354Phase 2, Phase 3
41Treatment of Adrenal Insufficiency in ChildrenCompletedNCT02720952Phase 3
42Genotropin Study Assessing Use of Injection PenCompletedNCT00965484Phase 3
43Treatment With Recombinant Human Growth Hormone Genotonorm (Registered) In Children With Short Stature SecondaryCompletedNCT00174278Phase 3
44Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone DeficiencyCompletedNCT00109733Phase 3
45Evaluation of Efficacy and Safety of Recombinant Somatroipn in Patients With Growth Hormone DeficiencyCompletedNCT02693522Phase 3
46A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone DeficiencyCompletedNCT02382939Phase 3
47A Follow-up Study to Examine the Presence of Anti-human Growth Hormone Antibodies Following a Study (FE 999905 CS07) of Zomacton in Children With Growth Hormone DeficiencyCompletedNCT02173821Phase 3
48Safety and Efficacy of Somatropin in Children With Growth Hormone DeficiencyCompletedNCT01502124Phase 3
49Phase III Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency ChildrenCompletedNCT01495468Phase 3
50Cross Over Convenience And Preference Study Of New Mark VII Compared To Genotropin Pen In Pediatric And Adult SubjectsCompletedNCT01112865Phase 3

Search NIH Clinical Center for Hypopituitarism


Cochrane evidence based reviews: hypopituitarism

Genetic Tests for Hypopituitarism

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Genetic tests related to Hypopituitarism:

id Genetic test Affiliating Genes
1 Hypopituitarism26

Anatomical Context for Hypopituitarism

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MalaCards organs/tissues related to Hypopituitarism:

35
Pituitary, Brain, Testes, Bone, Thyroid, Heart, Endothelial

Animal Models for Hypopituitarism or affiliated genes

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MGI Mouse Phenotypes related to Hypopituitarism:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.4GLI2, HESX1, IGF1, LHX3, POU1F1
2MP:00107687.5GLI2, HESX1, IGF1, INS, LHX3, LHX4
3MP:00053787.0GHRH, GLI2, HESX1, IGF1, INS, LHX3
4MP:00053766.6GHRH, GLI2, IGF1, INS, LHX3, LHX4
5MP:00053896.5GHRH, GLI2, IGF1, INS, LHX3, POU1F1
6MP:00053796.3GHRH, GLI2, HESX1, IGF1, INS, LHX3
7MP:00036316.2GHRH, GLI2, HESX1, IGF1, INS, LHX3

Publications for Hypopituitarism

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Articles related to Hypopituitarism:

(show top 50)    (show all 705)
idTitleAuthorsYear
1
Hypopituitarism-needs modern individualized treatment. (28004235)
2016
2
Hypopituitarism patterns among adult males with prolactinomas. (27038873)
2016
3
Intraparenchymal infiltration of Rathke's cleft cysts manifesting as severe neurological deficits and hypopituitarism: 2 case reports. (27094461)
2016
4
Excess mortality associated with hypopituitarism in adults: a meta-analysis of observational studies. (25658016)
2015
5
Hypopituitarism: A rare sequel of cerebral malaria - Presenting as delayed awakening from general anesthesia. (26417148)
2015
6
Novel lethal form of congenital hypopituitarism associated with the first recessive LHX4 mutation. (25871839)
2015
7
Chronic hypopituitarism is uncommon in survivors of aneurysmal subarachnoid haemorrhage. (24965315)
2014
8
Repeating ACTH Stimulation Test Is Necessary to Diagnose ACTH Deficiency in Neonatal Hypopituitarism With Initial False Negative Result. (27335928)
2014
9
Reliability of magnetic resonance imaging for the detection of hypopituitarism in children with optic nerve hypoplasia. (23972277)
2014
10
Sudden cardiac death as a result of neglected hypopituitarism. (23825983)
2013
11
Absent adrenarche in children with hypopituitarism: a study based on urinary steroid metabolomics. (23774132)
2013
12
Acute aortic dissection in a patient with untreated hypopituitarism. (23608931)
2013
13
Hypopituitarism due to primary empty sella and uncommon muscular symptoms. (21258802)
2012
14
Sturge-Weber syndrome: presentation with partial hypopituitarism. (23155711)
2012
15
Pathophysiology of hypopituitarism in the setting of brain injury. (18481181)
2012
16
Anterior hypopituitarism is rare and autoimmune disease is common in adults with idiopathic central diabetes insipidus. (22026638)
2012
17
A lifelong smoker with hypopituitarism: rethinking the hypothesis of a tumor in the hypophysis. (22577392)
2012
18
Low prevalence of hypopituitarism after traumatic brain injury: a multicenter study. (21646286)
2011
19
Hypopituitarism as unusual sequelae to central nervous system tuberculosis. (22029037)
2011
20
Increased transactivation associated with SOX3 polyalanine tract deletion in a patient with hypopituitarism. (21289259)
2011
21
Somatostatin-producing atypical null cell adenoma manifesting as severe hypopituitarism and rapid deterioration--case report. (20174891)
2010
22
Prevalence, natural history and consequences of posttraumatic hypopituitarism: a case for endocrine surveillance. (20158347)
2010
23
Hypopituitarism following traumatic brain injury: prevalence is affected by the use of different dynamic tests and different normal values. (19783619)
2010
24
All patients with 'idiopathic' hypopituitarism should be screened for hemochromatosis. (18270843)
2009
25
Prevalence of hypopituitarism in patients with cerebrovascular diseases. (19020380)
2008
26
Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism. (19093031)
2008
27
Is hypopituitarism predictable after traumatic brain injury? (18059377)
2008
28
Hypopituitarism following traumatic brain injury (TBI): call for attention. (16114279)
2005
29
Primary hypothyroidism associated with empty sella turcica and hypopituitarism]. (16296587)
2005
30
Hypopituitarism following traumatic brain injury. (15935980)
2005
31
Is hypopituitarism a common event following traumatic brain injury? (16929358)
2005
32
Evidence for developmental hypopituitarism in ill preterm infants. (15129226)
2004
33
A case of cystic lymphocytic hypophysitis with cacosmia and hypopituitarism. (15256785)
2004
34
Enhanced repression by HESX1 as a cause of hypopituitarism and septooptic dysplasia. (14557462)
2003
35
Severe hyponatremia as a frequent revealing sign of hypopituitarism after 60 years of age. (12943518)
2003
36
The spectrum of hypopituitarism caused by PROP1 mutations. (12464226)
2002
37
Spontaneous thrombosis of a giant internal carotid aneurysm in a patient who presented with hypopituitarism. (12617242)
2002
38
Medical management of hypopituitarism in patients with pituitary adenomas. (12675508)
2002
39
The "quality of life-assessment of growth hormone deficiency in adults" questionnaire: can it be used to assess quality of life in hypopituitarism? (11344182)
2001
40
Premature mortality and hypopituitarism. (11430385)
2001
41
The effects on insulin action in adult hypopituitarism of recombinant human GH therapy individually titrated for six months. (11701703)
2001
42
Rheumatoid factor positive hypertrophic cranial pachymeningitis in association with hypopituitarism and multiple cranial nerve palsies. (11579967)
2001
43
A case of torsade de pointes associated with hypopituitarism due to hemorrhagic fever with renal syndrome. (11410700)
2001
44
Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency. (11549653)
2001
45
Vasopressin and thirst in patients with posterior pituitary ectopia and hypopituitarism. (10931083)
2000
46
Congenital hypopituitarism in a 48-year old adult. Natural course, hormonal study and MRI evidence. (10941429)
1999
47
Hydrocortisone replacement therapy in children and adolescents with hypopituitarism. (9302370)
1997
48
Peripartum hypopituitarism and lymphocytic hypophysitis. (7648244)
1995
49
Selective hypopituitarism. Impaired cell-mediated immunity and chronic mucocutaneous candidiasis. (4740720)
1973
50
An endobronchial chondroma in a cachectic psychotic with hypopituitarism. (13253916)
1955

Variations for Hypopituitarism

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Expression for genes affiliated with Hypopituitarism

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Search GEO for disease gene expression data for Hypopituitarism.

Pathways for genes affiliated with Hypopituitarism

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GO Terms for genes affiliated with Hypopituitarism

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Cellular components related to Hypopituitarism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1secretory granule lumenGO:00347749.9INS, POMC
2intracellularGO:00056228.0GH1, GHRH, LHX3, LHX4, PRL
3extracellular regionGO:00055767.4GH1, GHRH, IGF1, INS, POMC, PRL

Biological processes related to Hypopituitarism according to GeneCards Suite gene sharing:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1somatotropin secreting cell differentiationGO:006012610.6POU1F1, PROP1
2medial motor column neuron differentiationGO:002152610.5LHX3, LHX4
3motor neuron axon guidanceGO:000804510.4LHX3, LHX4
4positive regulation of glycolytic processGO:004582110.3IGF1, INS
5positive regulation of glycogen biosynthetic processGO:004572510.2IGF1, INS
6activation of protein kinase B activityGO:003214810.2IGF1, INS
7positive regulation of tyrosine phosphorylation of Stat5 proteinGO:004252310.1GH1, IGF1
8positive regulation of glucose importGO:004632610.1IGF1, INS
9JAK-STAT cascade involved in growth hormone signaling pathwayGO:006039710.0GH1, PRL
10animal organ morphogenesisGO:000988710.0LHX3, LHX4, PROP1
11positive regulation of JAK-STAT cascadeGO:00464279.9GH1, PRL
12regulation of multicellular organism growthGO:00400149.7IGF1, PRL
13dorsal/ventral pattern formationGO:00099539.7GLI2, LHX3, PROP1
14positive regulation of phosphatidylinositol 3-kinase signalingGO:00140689.5GH1, IGF1, INS
15positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.5GH1, IGF1, INS
16positive regulation of mitotic nuclear divisionGO:00458409.5IGF1, INS
17cellular protein metabolic processGO:00442679.5IGF1, INS, PRL
18pituitary gland developmentGO:00219839.4GLI2, LHX3, POU1F1, SOX3
19positive regulation of insulin-like growth factor receptor signaling pathwayGO:00435689.4GH1, GHRH, IGF1
20positive regulation of DNA replicationGO:00457409.3GLI2, IGF1, INS
21adenohypophysis developmentGO:00219849.2GHRH, POU1F1, PROP1
22positive regulation of multicellular organism growthGO:00400189.0GH1, GHRH, POU1F1
23negative regulation of apoptotic processGO:00430668.8GLI2, IGF1, LHX3, LHX4, PROP1
24positive regulation of transcription from RNA polymerase II promoterGO:00459448.1GLI2, IGF1, LHX3, POMC, POU1F1, PROP1
25positive regulation of cell proliferationGO:00082847.5GHRH, GLI2, IGF1, INS, POU1F1

Molecular functions related to Hypopituitarism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1prolactin receptor bindingGO:000514810.2GH1, PRL
2insulin-like growth factor receptor bindingGO:000515910.2IGF1, INS
3insulin receptor bindingGO:00051589.6IGF1, INS
4chromatin bindingGO:00036829.0GLI2, HESX1, POU1F1, PROP1
5hormone activityGO:00051798.6GH1, IGF1, INS, POMC, PRL
6sequence-specific DNA bindingGO:00435658.3GLI2, HESX1, LHX3, LHX4, POU1F1

Sources for Hypopituitarism

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet