MCID: HYP083
MIFTS: 54

Hypopituitarism malady

Categories: Genetic diseases, Rare diseases, Endocrine diseases

Aliases & Classifications for Hypopituitarism

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Aliases & Descriptions for Hypopituitarism:

Name: Hypopituitarism 11 48 27 50 39 13 68
Pituitary Insufficiency 11 48
 
Pituitary Hormone Deficiency 11
Pituitary Hypofunction 11

Classifications:



External Ids:

Disease Ontology11 DOID:9406
ICD1030 E23.0, E23
MeSH39 D007018
NCIt45 C62591

Summaries for Hypopituitarism

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NIH Rare Diseases:48 Hypopituitarism occurs when the body has low levels of certain hormones made by the pituitary gland.  the pituitary gland normally makes several hormones (including growth hormone, thyroid stimulating hormone, adrenocorticotropic hormone, prolactin, follicle stimulating hormone and luteinizing hormone, vasopressin, and oxytocin).  these hormones are important for directing body growth and development, and for regulating blood pressure and metabolism.  symptoms of this condition vary and depend on which hormones are affected.  treatment depends on the cause of this condition; once the cause is corrected, medication (hormone replacement therapy) must be taken to provide the body with the normal amount of hormones. last updated: 7/20/2012

MalaCards based summary: Hypopituitarism, also known as pituitary insufficiency, is related to chondroma and fatty liver disease. An important gene associated with Hypopituitarism is PROP1 (PROP Paired-Like Homeobox 1), and among its related pathways are Glucocorticoid Pathway (HPA Axis), Pharmacodynamics and Glucocorticoid receptor regulatory network. Affiliated tissues include pituitary, brain and thyroid, and related mouse phenotypes are hearing/vestibular/ear and respiratory system.

Disease Ontology:11 A pituitary gland disease characterized by the decreased secretion of one or more of the eight hormones normally produced by the pituitary gland.

Wikipedia:71 Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced... more...

Related Diseases for Hypopituitarism

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Diseases in the Hypopituitarism family:

Familial Hypopituitarism

Diseases related to Hypopituitarism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 320)
idRelated DiseaseScoreTop Affiliating Genes
1chondroma29.1IGF1, INS, POMC
2fatty liver disease28.7CRH, INS, POMC, PRL
3pituitary hormone deficiency, combined, 312.3
4pituitary hormone deficiency, combined, 112.3
5choroideremia hypopituitarism11.9
6anterior pituitary insufficiency, familial11.9
7familial hypopituitarism11.9
8sheehan syndrome11.8
9corpus callosum dysgenesis hypopituitarism11.7
10distal arthrogryposis with hypopituitarism, intellectual disability and facial anomalies11.7
11hypopituitarism postaxial polydactyly11.7
12isolated growth hormone deficiency11.3
13combined pituitary hormone deficiencies, genetic forms11.2
14pallister-hall syndrome11.2
15lymphocytic hypophysitis11.1
16septooptic dysplasia11.1
17combined pituitary hormone deficiency11.1
18pituitary deficiency due to empty sella turcica syndrome11.1
19rhyns syndrome10.9
20holoprosencephaly-910.8
21culler-jones syndrome10.8
22laurence-moon syndrome10.8
23stiff-person syndrome10.8
24septo-optic dysplasia spectrum10.7
2510.4
26brain injury10.3
27traumatic brain injury10.3
28critical congenital heart disease10.3GH1, IGF1
29grin2a-related speech disorders and epilepsy10.2GH1, PRL
30mental retardation, x-linked syndromic, christianson type10.2POU1F1, PROP1, SOX3
31rolandic epilepsy, mental retardation, and speech dyspraxia10.2HESX1, SOX3
32cerebral hemisphere lipoma10.2GH1, PRL
33potter's syndrome10.2LHX3, PROP1
34vaginal adenoma10.2IGF1, POMC
35osseous heteroplasia, progressive10.2GH1, IGF1, PRL
36axial osteomalacia10.1GH1, IGF1, PRL
37dykes markes harper syndrome10.1GH1, GHRH, IGF1
38macrocephaly, benign familial10.1GH1, POMC
39blind loop syndrome10.1GH1, IGF1, INS
40sohval soffer syndrome10.1IGF1, IGFBP3
41diabetes insipidus10.1
42epidural spinal canal meningioma10.1IGF1, INS, PRL
43hyperlipoproteinemia type iii10.1INS, POMC
44african histoplasmosis10.1POMC, PRL
45aneurysm10.1
46pinguecula10.1IGF1, INS, PRL
47glaucoma, hereditary adult type 1a10.1GH1, GHRH, PRL
48glomangiomyoma10.1GH1, INS, PRL
49growth hormone deficiency10.1
50spondylometaphyseal dysplasia, megarbane-dagher-melike type10.0GH1, IGF1, IGFBP3

Graphical network of the top 20 diseases related to Hypopituitarism:



Diseases related to hypopituitarism

Symptoms & Phenotypes for Hypopituitarism

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MGI Mouse Phenotypes related to Hypopituitarism according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.6GLI2, HESX1, IGF1, LHX3, POU1F1
2MP:00053888.3CRH, GLI2, HESX1, IGF1, LHX4, PROP1
3MP:00053708.2CRH, GHRH, IGFBP3, INS, POMC, PRL
4MP:00053897.8GHRH, GLI2, IGF1, INS, LHX3, POU1F1
5MP:00107717.7CRH, GLI2, IGF1, IGFBP3, INS, POMC
6MP:00036316.5CRH, GHRH, GLI2, HESX1, IGF1, INS
7MP:00053786.3CRH, GHRH, GLI2, HESX1, IGF1, IGFBP3
8MP:00053765.9CRH, GHRH, GLI2, IGF1, IGFBP3, INS
9MP:00053795.7CRH, GHRH, GLI2, HESX1, IGF1, IGFBP3

Drugs & Therapeutics for Hypopituitarism

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Drugs for Hypopituitarism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 127)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CosyntropinapprovedPhase 42716960-16-016129617
Synonyms:
16960-16-0
ATCH (1-24)
Adrenocorticotropic hormone fragment 1-24 human, rat
COSYNTROPIN
Corticotropin tetracosapeptide
Cortrosyn
Cortrosyn (TN)
Cosyntropin
Cosyntropin (USAN)
 
D00284
Tetracosactide
Tetracosactide (INN)
Tetracosactrin
adrenocorticotropic hormone 1-24
alpha(1-24)-corticotrophin
beta(1-24)-corticotrophin
corticotropin-(1-24)
corticotropin-(1-24) tetracosapeptide
α1-24-corticotrophin
β1-24-corticotrophin
2
MethyltestosteroneapprovedPhase 4, Phase 256358-18-46010
Synonyms:
17(alpha)-Methyl-delta(4)-androsten-17(beta)-ol-3-one
17-Methyltestosterone
17-beta-Hydroxy-17-methylandrost-4-en-3-one
17-methyltestosterone
17alpha-Methyl-3-oxo-4-androsten-17beta-ol
17alpha-Methyl-delta(4)-androsten-17beta-ol-3-one
17alpha-Methyltestosterone
17alpha-methyl-delta-androsten-17beta-ol-3-one
17alpha-methyltestosterone
 
17beta-Hydroxy-17-methylandrost-4-en-3-one
17α-methyl-Δ4-androsten-17β-ol-3-one
17α-methyltestosterone
4-Androstene-17alpha-methyl-17beta-ol-3-one
Android
Methyltestosterone
Methyltestosteronum
Metiltestosterona
NSC-9701
Testred
Virilon
3
Testosteroneapproved, investigationalPhase 4, Phase 256358-22-06013
Synonyms:
(+)-testosterone
(+-)-8-iso-testosterone
(+-)-retrotestosterone
(+-)-testosterone
(17b)-17-hydroxy-androst-4-en-3-one
(17beta)-17-Hydroxyandrost-4-en-3-one
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
13-Iso-testosterone
17-Hydroxy-(17-beta)-androst-4-en-3-one
17-Hydroxy-(17beta)-androst-4-en-3-one
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
17-Hydroxy-D4-androsten-3-one
17-Hydroxy-androst-4-en-3-one
17-beta-Hydroxy-delta(sup 4)-androsten-3-one
17-beta-Hydroxyandrost-4-en-3-one
17?-Hydroxy-4-androsten-3-one
17a-Hydroxy-(13a)-androst-4-en-3-one
17a-Hydroxy-13a-androst-4-en-3-one
17a-Hydroxy-14b-androst-4-en-3-one
17a-Hydroxy-androst-4-en-3-one
17b-Hydroxy-(10a)-androst-4-en-3-one
17b-Hydroxy-(13a)-androst-4-en-3-one
17b-Hydroxy-(8a)-androst-4-en-3-one
17b-Hydroxy-(8a,10a)-androst-4-en-3-one
17b-Hydroxy-(9b)-androst-4-en-3-one
17b-Hydroxy-(9b,10a)-androst-4-en-3-one
17b-Hydroxy-13a-androst-4-en-3-one
17b-Hydroxy-8a-androst-4-en-3-one
17b-Hydroxy-D4-androsten-3-one
17b-Hydroxy-androst-4-en-3-on
17b-Hydroxy-androst-4-en-3-one
17b-Hydroxyandrost-4-en-3-one
17b-Hydroxyandrost-4-ene-3-one
17b-Testosterone
17b-hydroxy-4-androsten-3-one
17beta-Hydroxy-3-oxo-4-androstene
17beta-Hydroxy-4-androsten-3-one
17beta-Hydroxy-delta(sup4)-androsten-3-one
17beta-Hydroxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-ene-3-one
17beta-hydroxy-4-androsten-3-one
4-Androsten-17?-ol-3-one
4-Androsten-17beta-ol-3-one
4-Androsten-3-one-17b-ol
4-androsten-17β-ol-3-one
4-androstene-17beta-ol-3-one
46923_FLUKA
46923_RIEDEL
58-22-0
7-beta-Hydroxyandrost-4-en-3-one
8-Iso-testosterone
9b,10a-Testosterone
9b-Testosterone
AA 2500
AC-14899
AC1L1LM0
Andriol
Andro
Andro 100
Andro L.A. 200
AndroGel
Androderm
Androderm (TN)
Androgel
Androgel (TN)
Android 10
Android 25
Android 5
Androlin
Andronaq
Andronate 100
Andronate 200
Andropatch
Andropository 200
Androsorb
Androst-4-en-17b-ol-3-one
Androst-4-en-17beta-ol-3-one
Androst-4-ene-17b-ol-3-one
Andrusol
Andryl 200
B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E
BIDD:ER0555
BIM-0061761.0001
Beta Testosterone
Bio-0678
Bio-T-Gel
C00535
CCRIS 574
CDB 111C
CHEBI:17347
CHEMBL386630
CID6013
CMC_13449
COL 1621
CP 601B
CPD000058344
Cristerona T
Cristerone T
D00075
D4-Androsten-17b-ol-3-one
DB00624
Dea No. 4000
Delatest
Delatestryl
Depo-Testadiol
Depo-Testosterone
Depo-Testosterone Cypionate
Depotest
EINECS 200-370-5
Epitestosteron
Everone 200
Geno-Cristaux Gremy
Geno-cristaux Gremy
Geno-cristaux gremy
HMS2052N11
HSDB 3398
Halotensin
Homosteron
Homosterone
 
Intrinsa
LMST02020002
LS-148813
LibiGel
Libigel
Lumitestosteron
MLS000563091
MLS001032098
MLS001306401
MLS002174283
Malerone
Malestrone
Malestrone (amps)
Malogen in Oil
Malogen, Aquaspension Injection
Malogen, aquaspension injection
Mertestate
Metandren
Methyltestosterone
MolPort-002-506-901
NCGC00091018-01
NSC 9700
Neo-Hombreol F
Neo-Testis
Neo-testis
Neotestis
Oreton
Oreton F
Oreton Methyl
Oreton-F
Orquisteron
Perandren
Percutacrine Androgenique
Percutacrine androgenique
Primotest
Primoteston
Rac-17b-hydroxy-(13a)androst-4-en-3-one
Rac-17b-hydroxy-(8a)-androst-4-en-3-one
Rac-17b-hydroxy-(9b,10a)androst-4-en-3-one
Rac-17b-hydroxy-androst-4-en-3-one
Relibra
Retrotestosterone
S00309
S2033_Selleck
SAM001246921
SMR000058344
SMR001261453
Scheinpharm Testone-Cyp
Striant
Striant (TN)
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
T1500_SIGMA
T5411_FLUKA
T5411_SIGMA
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testiculosterone
Testim
Testim (TN)
Testobase
Testoderm
Testoderm Tts
Testogel
Testoject-50
Testolent
Testolin
Testopel Pellets
Testopropon
Testosteroid
Testosteron
Testosterona
Testosterona [INN-Spanish]
Testosterone
Testosterone (JAN/USP)
Testosterone Cypionate
Testosterone Enanthate
Testosterone Hydrate
Testosterone [Androgenic steroids, anabolic]
Testosterone [INN:BAN]
Testosterone and its esters
Testosterone hydrate
Testosterone solution
Testosteronum
Testosteronum [INN-Latin]
Testostosterone
Testostérone
Testoviron
Testoviron Schering
Testoviron T
Testoxyl
Testred
Testred Cypionate 200
Testrin-P.A
Testro AQ
Testro Aq
Testrone
Testryl
Tostrelle
Tostrex
Trans-Testosterone
UNII-3XMK78S47O
Viatrel
Virilon
Virilon IM
Virormone
Virosterone
ZINC06500184
beta testosterone
delta(sup 4)-Androsten-17(beta)-ol-3-one
delta4-Androsten-17beta-ol-3-one
delta4-androsten-17b-ol-3-one
testosterone
trans-Testosterone
4
Hydrocortisoneapproved, vet_approvedPhase 4, Phase 3, Phase 2, Early Phase 166750-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
5
Epinephrineapproved, vet_approvedPhase 4, Phase 3, Phase 298551-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
6Epinephryl boratePhase 4, Phase 3, Phase 2985
7Hydrocortisone 17-butyrate 21-propionatePhase 4, Phase 3, Phase 2, Early Phase 1667
8Hydrocortisone acetatePhase 4, Phase 3, Phase 2, Early Phase 1667
9Anabolic AgentsPhase 4, Phase 2513
10MitogensPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 11617
11Insulin, Globin ZincPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 14645
12insulinPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 14646
13RacepinephrinePhase 4, Phase 3, Phase 2985
14HormonesPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 114415
15Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 113180
16Antineoplastic Agents, HormonalPhase 4, Phase 2, Phase 35592
17Cortisol succinatePhase 4, Phase 3, Phase 2, Early Phase 1667
18Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 113168
19AndrogensPhase 4, Phase 2, Phase 31321
20Anti-Inflammatory AgentsPhase 4, Early Phase 110729
21
Testosterone enanthatePhase 4, Phase 2563315-37-79416
Synonyms:
17-((1-Oxoheptyl)oxy)androst-4-en-3-one
17-Hydroxyandrost-4-en-3-one, 17-heptanoate
17-Hydroxyandrost-4-en-3-one, 17-heptanoic acid
17beta-Enanthoxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-en-3-one enanthate
4-Androsten-17beta-ol-3-one 17-enanthate
4-Androsten-3-one 17beta-enanthate
Androgyn L.A.
Andropository
Androtardyl
Atlatest
DEA No. 4000
DePatestrye
Delatest
Delatestryl
Depo-Testro Med
Ditate
Durathate
Everone
 
Exten test
Malogen L.A.
Malogen L.A.200
Orquisteron-E
Primotestone
Reposo TMD
Testanthate
Testate
Testenate
Testinon
Testoenant
Testonenant
Testosterone 17-enanthate
Testosterone 17beta-heptanoate
Testosterone 17beta-heptanoic acid
Testosterone enantate
Testosterone heptoate
Testosterone heptoic acid
Testosterone heptylate
Testosterone oenanthate
Testostroval
22Testosterone undecanoatePhase 4, Phase 2563
23Testosterone 17 beta-cypionatePhase 4, Phase 2563
24Pharmaceutical SolutionsPhase 4, Phase 3, Phase 28192
25
ZincapprovedPhase 3, Early Phase 122967440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
26
BenzocaineapprovedPhase 320161994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
27
ClonidineapprovedPhase 32404205-90-72803
Synonyms:
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI)
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2,6-dichloro-N-(2-imidazolidinylidene)aniline
2,6-dichloro-N-2-imidazolidinylidenebenzenamide
2,6-dichloro-N-imidazolidin-2-ylideneaniline
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
2-(2,6-Dichlorophenylimino)imidazolidine
2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI)
2-[(2,6-Dichlorophenyl)imino]imidazoline
2-[(2,6-dichlorophenyl)imino]-2-imidazoline
4205-90-7
4205-91-8 (mono-hydrochloride)
57066-25-8
734571A
AB00514634
AC1L1EI5
AC1Q3K6V
AKOS001595470
Adesipress
BIDD:GT0547
BPBio1_000040
BRD-K98530306-001-02-1
BRD-K98530306-003-05-0
BSPBio_000036
BSPBio_001588
BSPBio_002055
Bio1_000470
Bio1_000959
Bio1_001448
Bio2_000308
Bio2_000788
C9H9Cl2N3
CAS-4205-91-8
CATAPRES-TTS-1
CATAPRES-TTS-2
CATAPRES-TTS-3
CCRIS 7787
CHEBI:3757
CHEBI:46632
CHEMBL134
CID2803
Catapres
Catapres- TTS
Catapres-TTS
Catapresan
Catapressan
Catarpres
Catarpres-TTS
Catarpres-TTS (TN)
Catarpresan
Chlofazoline
Chlornidinum
Clofenil
Clonidin
Clonidina
Clonidina [INN-Spanish]
Clonidine (JAN/USAN/INN)
Clonidine HCl
Clonidine [USAN:BAN:INN]
Clonidinhydrochlorid
Clonidinum
Clonidinum [INN-Latin]
Clonistada
Clopheline
D00281
DB00575
DB07566
DivK1c_000774
 
Dixarit
Duraclon
Duraclont
EINECS 224-119-4
Gemiton
HMS1361P10
HMS1791P10
HMS1989P10
HMS2089G11
HSDB 3040
Hemiton
IDI1_000774
IDI1_034058
Ipotensium
Isoglaucon
KBio1_000774
KBio2_000308
KBio2_001821
KBio2_002876
KBio2_004389
KBio2_005444
KBio2_006957
KBio3_000615
KBio3_000616
KBio3_001275
KBioGR_000308
KBioGR_001572
KBioSS_000308
KBioSS_001821
Klofelin
Klofenil
L000193
LS-79606
Lopac-C-7897
Lopac0_000268
M 5041T
M-5041T
MolPort-001-779-668
MolPort-005-932-374
N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
NCGC00015268-01
NCGC00015268-02
NCGC00015268-08
NCGC00024734-01
NCGC00024734-02
NCGC00024734-03
NCGC00024734-04
NCGC00024734-05
NCGC00179680-01
NINDS_000774
Prestwick0_000248
Prestwick1_000248
Prestwick2_000248
Prestwick3_000248
SKF 34427
SPBio_001233
SPBio_002255
ST 155BS
ST-155-BS
ST-155BS
Spectrum2_001187
Spectrum3_000358
Spectrum4_000956
Spectrum5_000759
Spectrum_001341
T171
Tenso-Timelets
Tocris-0690
UNII-MN3L5RMN02
ZINC00896484
clonidine
nchembio.79-comp11
nchembio705-10
28
Anastrozoleapproved, investigationalPhase 2, Phase 3279120511-73-12187
Synonyms:
.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
120511-73-1
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
AC-4234
AC1L1D49
Anastrazole
Anastrole
Anastrozol
Anastrozole (JAN/USAN/INN)
Anastrozole [USAN:INN:BAN]
Arimidex
Arimidex (TN)
Arimidex (Zeneca)
Arimidex, Anastrozole
Asiolex
Astra brand of anastrozole
AstraZeneca brand of anastrozole
C08159
C090450
C17H19N5
CHEBI:2704
CHEMBL1399
CID2187
CPD000466301
 
D00960
DB01217
HMS2052M11
HMS2089N10
HSDB 7462
I06-0021
ICI D1033
ICI-D 1033
ICI-D1033
LS-29563
MLS000759396
MLS001424217
MolPort-005-933-078
NCGC00164619-01
NSC719344
S1188_Selleck
SAM001246525
SBB066057
SMR000466301
UNII-2Z07MYW1AZ
ZD 1033
ZD-1033
ZD1033
ZINC00000941
Zeneca ZD 1033
Zeneca brand of anastrozole
alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
anastrazole
anastrozole
29
Lidocaineapproved, vet_approvedPhase 2, Phase 31317137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
30tannic acidapproved, NutraceuticalPhase 32016
31Hypoglycemic AgentsPhase 3, Early Phase 15896
32AnestheticsPhase 2, Phase 39596
33Neurotransmitter AgentsPhase 3, Phase 218340
34Autonomic AgentsPhase 3, Phase 210150
35Antihypertensive AgentsPhase 34207
36Respiratory System AgentsPhase 2, Phase 34997
37AnalgesicsPhase 3, Phase 211733
38SympatholyticsPhase 3580
39Peripheral Nervous System AgentsPhase 3, Phase 223689
40Adrenergic AgonistsPhase 3, Phase 23027
41Steroid Synthesis InhibitorsPhase 2, Phase 31763
42AntibodiesPhase 3, Phase 26394
43Adrenergic alpha-AgonistsPhase 3, Phase 21734
44Estrogen AntagonistsPhase 2, Phase 31349
45Aromatase InhibitorsPhase 2, Phase 3826
46ImmunoglobulinsPhase 3, Phase 26394
47EstrogensPhase 2, Phase 32542
48Adrenergic AgentsPhase 3, Phase 25352
49Adrenergic alpha-2 Receptor AgonistsPhase 3980
50Growth Hormone-Releasing HormonePhase 3, Phase 2, Phase 130

Interventional clinical trials:

(show top 50)    (show all 224)
idNameStatusNCT IDPhase
1Testosterone Gel Applied to Women With Pituitary Gland ProblemsUnknown statusNCT00144391Phase 4
2Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen TestUnknown statusNCT00851942Phase 4
3Comparison of Two Growth Hormone Dosing Methods in Adults With Growth Hormone DeficiencyCompletedNCT00490191Phase 4
4Effect of 5 Years of GH Replacement on AtherosclerosisCompletedNCT00462475Phase 4
5Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve HypoplasiaCompletedNCT00140413Phase 4
6Phase 4 Study in Secondary Hypothyroidism: Body Weight Adapted Thyroxin Treatment and Triiodothyronine SupplementationCompletedNCT00360074Phase 4
7A Multicentre, Randomised, Open-label, Controlled Study to Evaluate the Effects of Saizen® on Cardiac Function in Growth Hormone Deficient(GHD) Subjects During the Transition Phase From Childhood to AdulthoodCompletedNCT01157793Phase 4
8Growth Hormone and Endothelial Function in ChildrenCompletedNCT00373386Phase 4
9Bone Mineral Density (BMD) in Adolescents With Growth Hormone Deficiency (GHD)CompletedNCT00097526Phase 4
10An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)CompletedNCT01806298Phase 4
11Safety and Efficacy of SR-hGH (Sustained-release Human Growth Hormone, Declage Inj.)CompletedNCT01605331Phase 4
12Effect of Somatropin on Left Ventricular Mass in Growth Hormone Deficient Adult PatientsCompletedNCT01562834Phase 4
13Comparison of a Needle-free Injection Method With a Needle-syringe Injection MethodCompletedNCT00990340Phase 4
14Growth Hormone and Glucose MetabolismCompletedNCT00929799Phase 4
15Easypod United States User TrialCompletedNCT00689260Phase 4
16Liquid Somatropin Formulation in Children With Growth Hormone DeficiencyCompletedNCT00567385Phase 4
17A Post Marketing Surveillance Study for NutropinAq® in Adults With Growth Hormone DeficiencyCompletedNCT00455884Phase 4
18Predictive Markers in GHD and TS Children Treated With SAIZEN®CompletedNCT00256126Phase 4
19IGF1 Generation TestCompletedNCT00145457Phase 4
20GH and Cardiovascular Risk FactorsCompletedNCT01877512Phase 4
21First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation StudyCompletedNCT01419249Phase 4
22Is There a Sensibility Increased in the Growth Hormone at Child With Prader-Willi Syndrome?CompletedNCT01298180Phase 4
23Norditropin NordiFlex® Device Compared to the Device Previously Used by Patients or ParentsCompletedNCT01245374Phase 4
24Predictive Markers in Chinese Growth Hormone Deficiency (GHD) Children Treated With Saizen®CompletedNCT01187550Phase 4
25Anterior Pituitary Hormone Replacement in Traumatic Brain InjuryCompletedNCT00957671Phase 4
26A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in BloodCompletedNCT00212758Phase 4
27National Cooperative Growth Study (NCGS) of Optimal Nutropin AQ and Nutropin Dosing in Pubertal Growth Hormone-Deficient (GHD) PatientsCompletedNCT00097513Phase 4
28Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone DeficiencyRecruitingNCT02976675Phase 4
29Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone DeficiencyRecruitingNCT02908958Phase 4
30Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children (Clinical Trial I)RecruitingNCT02380235Phase 4
31Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.RecruitingNCT03015909Phase 4
32Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency ChildrenRecruitingNCT02314676Phase 4
33A Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) Injection (Nutropin AQ®) in Children With Growth Hormone DeficiencyActive, not recruitingNCT02311894Phase 4
34Cardiovascular Effects on Growth Hormone Therapy in Adults With Growth Hormone DeficiencyTerminatedNCT01698944Phase 4
35A Study to Evaluate the Efficacy of Somatropin in Adults With Growth Hormone Deficiency Caused by Trauma and/or Head InjuryTerminatedNCT00638053Phase 4
36Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain InjuryTerminatedNCT00555009Phase 4
37Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain Injury.WithdrawnNCT00432263Phase 4
38Treatment of Children With Insufficient Secretion of Growth HormoneUnknown statusNCT00271518Phase 3
39Arimidex Multicenter Trial in Growth Hormone (GH) Deficient BoysCompletedNCT00133354Phase 2, Phase 3
40Treatment of Adrenal Insufficiency in ChildrenCompletedNCT02720952Phase 3
41Genotropin Study Assessing Use of Injection PenCompletedNCT00965484Phase 3
42Treatment With Recombinant Human Growth Hormone Genotonorm (Registered) In Children With Short Stature SecondaryCompletedNCT00174278Phase 3
43Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone DeficiencyCompletedNCT00109733Phase 3
44Evaluation of Efficacy and Safety of Recombinant Somatroipn in Patients With Growth Hormone DeficiencyCompletedNCT02693522Phase 3
45Validation of Macimorelin as a Test for Adult Growth Hormone DeficiencyCompletedNCT02558829Phase 3
46A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone DeficiencyCompletedNCT02382939Phase 3
47A Follow-up Study to Examine the Presence of Anti-human Growth Hormone Antibodies Following a Study (FE 999905 CS07) of Zomacton in Children With Growth Hormone DeficiencyCompletedNCT02173821Phase 3
48Safety and Efficacy of Somatropin in Children With Growth Hormone DeficiencyCompletedNCT01502124Phase 3
49Phase III Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency ChildrenCompletedNCT01495468Phase 3
50Cross Over Convenience And Preference Study Of New Mark VII Compared To Genotropin Pen In Pediatric And Adult SubjectsCompletedNCT01112865Phase 3

Search NIH Clinical Center for Hypopituitarism


Cochrane evidence based reviews: hypopituitarism

Genetic Tests for Hypopituitarism

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Genetic tests related to Hypopituitarism:

id Genetic test Affiliating Genes
1 Hypopituitarism27

Anatomical Context for Hypopituitarism

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MalaCards organs/tissues related to Hypopituitarism:

36
Pituitary, Brain, Thyroid, Testes, Bone, B cells, Endothelial

Publications for Hypopituitarism

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Articles related to Hypopituitarism:

(show top 50)    (show all 705)
idTitleAuthorsYear
1
CARDIAC STRUCTURAL AND FUNCTIONAL ABNORMALITIES IN FEMALES WITH UNTREATED HYPOPITUITARISM DUE TO SHEEHAN SYNDROME: RESPONSE TO HORMONE REPLACEMENT THERAPY. (27359291)
2016
2
Unusual association of turner syndrome and hypopituitarism in a Tunisian family. (27140594)
2016
3
The effect of growth hormone replacement on the thyroid axis in patients with hypopituitarism: in vivo and ex vivo studies. (27809356)
2016
4
Loperamide-induced hypopituitarism. (27681351)
2016
5
The effect of hypopituitarism on fatigue after subarachnoid hemorrhage. (27128968)
2016
6
Bilateral Carotid-Cavernous Fistulas: An Uncommon Cause of Pituitary Enlargement and Hypopituitarism. (27651959)
2016
7
The effect of growth hormone replacement in patients with hypopituitarism on pituitary tumor recurrence, secondary cancer, and stroke. (27815769)
2016
8
HESX1 Mutations in Patients with Congenital Hypopituitarism: Variable Phenotypes with the Same Genotype. (27000987)
2016
9
Hypopituitarism patterns among adult males with prolactinomas. (27038873)
2016
10
Circulating MicroRNAs as Potential Biomarkers for Traumatic Brain Injury-Induced Hypopituitarism. (27027233)
2016
11
Recovery of adrenal function after chronic secondary adrenal insufficiency in patients with hypopituitarism. (26928716)
2016
12
Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline. (27736313)
2016
13
Neuroendocrine Disturbances One to Five or More Years after Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage: Data from the German Database on Hypopituitarism. (26914840)
2016
14
Hypopituitarism: An uncommon cause of developmental delay. (27452620)
2016
15
A patient with pseudohypoaldosteronism type II complicated by congenital hypopituitarism carrying a KLHL3 mutation. (27780982)
2016
16
Cancerous leptomeningitis and familial congenital hypopituitarism. (26886902)
2016
17
A unique case of Shwachman-Diamond syndrome presenting with congenital hypopituitarism. (27754968)
2016
18
Reversible Hypopituitarism Associated with Intravascular Large B-Cell Lymphoma: Case Report of Successful Immunochemotherapy. (26936510)
2016
19
Cholesteatoma in the Sellar Region Presenting as Hypopituitarism and Diabetes Insipidus. (26962793)
2016
20
Endocrinology Update: Hypopituitarism. (27936532)
2016
21
Hypopituitarism in the elderly: a narrative review on clinical management of hypothalamic-pituitary-gonadal, hypothalamic-pituitary-thyroid and hypothalamic-pituitary-adrenal axes dysfunction. (27209187)
2016
22
Growth hormone deficiency and hypopituitarism in adults after complicated mild traumatic brain injury. (27878771)
2016
23
Evaluation and Initial Management of Hypopituitarism. (27587639)
2016
24
Partial hypopituitarism in a female patient with a 45,X/46,XY mosaicism. (27988022)
2016
25
IGF-I levels reflect hypopituitarism severity in adults with pituitary dysfunction. (27083162)
2016
26
Hypopituitarism Presenting as Adrenal Insufficiency and Hypothyroidism in a Patient with Wilson's Disease: a Case Report. (27478349)
2016
27
HORMONE SUBSTITUTION AFTER GASTRIC BYPASS SURGERY IN PATIENTS WITH HYPOPITUITARISM SECONDARY TO CRANIOPHARYNGIOMA. (26789341)
2016
28
Four-year follow-up of a Wilson disease pedigree complicated with epilepsy and hypopituitarism: Case report with a literature review. (27930511)
2016
29
VARIATIONS IN CLINICAL AND IMAGING FINDINGS BY TIME OF DIAGNOSIS IN FEMALES WITH HYPOPITUITARISM ATTRIBUTED TO LYMPHOCYTIC HYPOPHYSITIS. (26595515)
2016
30
Anterior Hypopituitarism and Treatment Response in Hunter Syndrome: A Comparison of Two Patients. (28018694)
2016
31
Regulation of fuel metabolism during exercise in hypopituitarism with growth hormone-deficiency (GHD). (27084998)
2016
32
Hypopituitarism following rifle cleaning accident. (27934815)
2016
33
A case of hypopituitarism accompanying Kearns-Sayre syndrome treated with human chorionic gonadotropin: A case report and literature review. (27709644)
2016
34
Intraparenchymal infiltration of Rathke's cleft cysts manifesting as severe neurological deficits and hypopituitarism: 2 case reports. (27094461)
2016
35
Concurrent hypopituitarism and leukemic retinopathy in a child with B-precursor acute lymphoblastic leukemia and isolated central nervous system relapse. (27536191)
2016
36
Hypopituitarism in children with cerebral palsy. (27789461)
2016
37
Hypopituitarism. (27041067)
2016
38
Mortality in adults with hypopituitarism: a systematic review and meta-analysis. (27817141)
2016
39
Hypopituitarism and goitre as endocrine manifestation of Langerhans cell histiocytosis (LCH). Case Report. (27618599)
2016
40
How should we interrogate the hypothalamic-pituitary-adrenal axis in patients with suspected hypopituitarism? (27316460)
2016
41
Hypopituitarism-needs modern individualized treatment. (28004235)
2016
42
Excess mortality associated with hypopituitarism in adults: a meta-analysis of observational studies. (25658016)
2015
43
A Rare Case of Isolated Cerebral Sarcoidosis Presenting as Suprasellar Mass Lesion with Salt-Wasting Hypopituitarism. (26251792)
2015
44
Patient reported outcome in posttraumatic pituitary deficiency: results from The Danish National Study on posttraumatic hypopituitarism. (25766045)
2015
45
Comments on Auble et al. Regarding Hypopituitarism in Pediatric Survivors of Inflicted Traumatic Brain Injury. (26414281)
2015
46
Characterization of facial phenotypes of children with congenital hypopituitarism and their parents: A matched case-control study. (25845580)
2015
47
Clinical and diagnostic approach to patients with hypopituitarism due to traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), and ischemic stroke (IS). (26573924)
2015
48
Anterior hypopituitarism in adult survivors of childhood cancers treated with cranial radiotherapy: a report from the St Jude Lifetime Cohort study. (25559807)
2015
49
Decreased apparent diffusion coefficient in the pituitary and correlation with hypopituitarism in patients with traumatic brain injury. (25679273)
2015
50
A Case of IgG4-Related Hypophysitis Presented with Hypopituitarism and Diabetes Insipidus. (25861230)
2015

Variations for Hypopituitarism

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Expression for genes affiliated with Hypopituitarism

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Search GEO for disease gene expression data for Hypopituitarism.

GO Terms for genes affiliated with Hypopituitarism

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Cellular components related to Hypopituitarism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endosome lumenGO:003190410.0GH1, INS, PRL
2insulin-like growth factor binding protein complexGO:00169429.4IGF1, IGFBP3
3insulin-like growth factor ternary complexGO:00425679.4IGF1, IGFBP3
4extracellular regionGO:00055767.4CRH, GH1, GHRH, IGF1, IGFBP3, INS
5extracellular spaceGO:00056157.2CRH, GH1, GHRH, IGF1, IGFBP3, INS

Biological processes related to Hypopituitarism according to GeneCards Suite gene sharing:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1medial motor column neuron differentiationGO:002152610.7LHX3, LHX4
2motor neuron axon guidanceGO:000804510.7LHX3, LHX4
3positive regulation of tyrosine phosphorylation of Stat5 proteinGO:004252310.6GH1, IGF1
4JAK-STAT cascade involved in growth hormone signaling pathwayGO:006039710.6GH1, PRL
5positive regulation of JAK-STAT cascadeGO:004642710.5GH1, PRL
6animal organ morphogenesisGO:000988710.5LHX3, LHX4, PROP1
7activation of protein kinase B activityGO:003214810.5IGF1, INS
8positive regulation of glycogen biosynthetic processGO:004572510.4IGF1, INS
9positive regulation of glycolytic processGO:004582110.4IGF1, INS
10hypothalamus developmentGO:002185410.4CRH, SOX3
11positive regulation of mitotic nuclear divisionGO:004584010.4IGF1, INS
12parturitionGO:000756710.4CRH, PRL
13adenohypophysis developmentGO:002198410.3GHRH, POU1F1, PROP1
14positive regulation of multicellular organism growthGO:004001810.2GH1, GHRH, POU1F1
15regulation of insulin-like growth factor receptor signaling pathwayGO:004356710.1IGFBP3, POU1F1
16dorsal/ventral pattern formationGO:000995310.1GLI2, LHX3, PROP1
17positive regulation of peptidyl-tyrosine phosphorylationGO:005073110.1GH1, IGF1, INS
18positive regulation of phosphatidylinositol 3-kinase signalingGO:001406810.1GH1, IGF1, INS
19somatotropin secreting cell differentiationGO:006012610.0POU1F1, PROP1
20lung developmentGO:00303249.8CRH, GLI2, LHX3
21positive regulation of DNA replicationGO:00457409.8GLI2, IGF1, INS
22positive regulation of MAPK cascadeGO:00434109.6IGF1, IGFBP3, INS
23negative regulation of transcription from RNA polymerase II promoterGO:00001229.6GLI2, HESX1, POU1F1, PROP1, SOX3
24negative regulation of apoptotic processGO:00430669.6GLI2, IGF1, LHX3, LHX4, PROP1
25pituitary gland developmentGO:00219839.5GLI2, HESX1, LHX3, POU1F1, SOX3
26positive regulation of insulin-like growth factor receptor signaling pathwayGO:00435689.3GH1, GHRH, IGF1, IGFBP3
27cellular protein metabolic processGO:00442679.3IGF1, IGFBP3, INS, PRL
28positive regulation of transcription from RNA polymerase II promoterGO:00459449.1GLI2, IGF1, LHX3, POMC, POU1F1, PROP1
29positive regulation of cell proliferationGO:00082848.2CRH, GHRH, GLI2, IGF1, INS, POU1F1
30regulation of transcription, DNA-templatedGO:00063557.8GLI2, HESX1, INS, LHX3, LHX4, POU1F1

Molecular functions related to Hypopituitarism according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1prolactin receptor bindingGO:000514810.5GH1, PRL
2insulin-like growth factor receptor bindingGO:000515910.3IGF1, INS
3chromatin bindingGO:00036829.8GLI2, HESX1, POU1F1, PROP1
4RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:00009789.7GLI2, HESX1, LHX3, POU1F1
5hormone activityGO:00051798.7CRH, GH1, IGF1, INS, POMC, PRL
6sequence-specific DNA bindingGO:00435658.6GLI2, HESX1, LHX3, LHX4, POU1F1, PROP1

Sources for Hypopituitarism

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet