MCID: HYP281
MIFTS: 20

Hypoproteinemia, Hypercatabolic malady

Genetic diseases (common) category

Summaries for Hypoproteinemia, Hypercatabolic

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48OMIM, 34MalaCards
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MalaCards: Hypoproteinemia, Hypercatabolic is related to chronic pyelonephritis and pyelonephritis. An important gene associated with Hypoproteinemia, Hypercatabolic is B2M (beta-2-microglobulin). The compounds polyether sulfone and iopentol have been mentioned in the context of this disorder.

Description from OMIM:48 241600

Aliases & Classifications for Hypoproteinemia, Hypercatabolic

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Sources:
48OMIM, 46Novoseek
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Aliases & Descriptions:

hypoproteinemia, hypercatabolic 48 46


Related Diseases for Hypoproteinemia, Hypercatabolic

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Hypoproteinemia, Hypercatabolic:



Diseases related to hypoproteinemia, hypercatabolic

Symptoms for Hypoproteinemia, Hypercatabolic

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48OMIM
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Symptoms by clinical synopsis from OMIM:

241600

Clinical features from OMIM:

241600

Drugs & Therapeutics for Hypoproteinemia, Hypercatabolic

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Hypoproteinemia, Hypercatabolic

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Anatomical Context for Hypoproteinemia, Hypercatabolic

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Animal Models for Hypoproteinemia, Hypercatabolic or affiliated genes

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Publications for Hypoproteinemia, Hypercatabolic

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Variations for Hypoproteinemia, Hypercatabolic

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Sources:
65UniProtKB/Swiss-Prot, 1 National Center for Biotechnology Information (Clinvar)
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UniProtKB/Swiss-Prot genetic disease variations for Hypoproteinemia, Hypercatabolic:

65
id Symbol AA change Variation ID SNP ID
1B2Mp.Ala11ProVAR_030660

Clinvar genetic disease variations for Hypoproteinemia, Hypercatabolic:

1
id Gene Name Type Significance SNP ID Assembly Location
1B2MNM_004048.2(B2M): c.31G> C (p.Ala11Pro)single nucleotide variantPathogenicrs104894481GRCh37Chr 15, 45003775: 45003775

Expression for genes affiliated with Hypoproteinemia, Hypercatabolic

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypoproteinemia, Hypercatabolic

Search GEO for disease gene expression data for Hypoproteinemia, Hypercatabolic.

Pathways for genes affiliated with Hypoproteinemia, Hypercatabolic

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Compounds for genes affiliated with Hypoproteinemia, Hypercatabolic

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Sources:
46Novoseek, 12DrugBank, 52PharmGKB, 30IUPHAR, 25HMDB, 62Tocris Bioscience
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Compounds related to Hypoproteinemia, Hypercatabolic according to GeneCards/GeneDecks:

(show all 31)
idCompoundScoreTop Affiliating Genes
1polyether sulfone469.7ALB, B2M
2iopentol469.7ALB, B2M
3p-aminohippuric acid469.7ALB, B2M
451-cr-edta469.7ALB, B2M
5icodextrin46 1210.7B2M, ALB
6iohexol469.7ALB, B2M
7inulin469.7ALB, B2M
8gamma globulin469.7ALB, B2M
9pentosidine469.7B2M, ALB
10sevoflurane52 46 1211.7ALB, B2M
11l-tryptophan52 30 46 25 1213.7B2M, ALB
12polysulfone469.7ALB, B2M
13cellulose acetate469.7ALB, B2M
1425-hydroxyvitamin d469.6ALB, B2M
15phosphorus469.6B2M, ALB
16captopril46 62 52 30 1213.6ALB, B2M
17vitamin b12469.6ALB, B2M
18bicarbonate469.6B2M, ALB
19uric acid46 2510.6ALB, B2M
20zidovudine46 52 1211.6ALB, B2M
21mannitol46 1210.5ALB, B2M
22urea46 25 1211.5B2M, ALB
23thyroxine46 2510.5ALB, B2M
24hyaluronic acid46 2510.4ALB, B2M
25ivig469.4ALB, FCGRT
26folate469.4ALB, B2M
27calcitriol46 62 25 1212.3B2M, ALB
28vitamin d469.3ALB, B2M
29vitamin a46 25 1211.2ALB, B2M
30indomethacin46 30 62 1212.0ALB, B2M
31iron46 259.9ALB, FCGRT, B2M

GO Terms for genes affiliated with Hypoproteinemia, Hypercatabolic

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17Gene Ontology
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Biological processes related to Hypoproteinemia, Hypercatabolic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1retina homeostasisGO:0018959.3ALB, B2M

Products for genes affiliated with Hypoproteinemia, Hypercatabolic

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hypoproteinemia, Hypercatabolic

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet