Aliases & Classifications for Hypopyon

MalaCards integrated aliases for Hypopyon:

Name: Hypopyon 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10443
ICD10 33 H20.05
ICD9CM 35 364.05
NCIt 47 C50593
SNOMED-CT 64 87807004
UMLS 69 C0020641

Summaries for Hypopyon

MalaCards based summary : Hypopyon is related to hypopyon ulcer and behcet syndrome. An important gene associated with Hypopyon is MRAP (Melanocortin 2 Receptor Accessory Protein), and among its related pathways/superpathways is Cell adhesion molecules (CAMs). The drugs Difluprednate and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye, myeloid and testes.

Wikipedia : 72 Hypopyon is a medical condition involving inflammatory cells in the anterior chamber of the... more...

Related Diseases for Hypopyon

Diseases related to Hypopyon via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)
id Related Disease Score Top Affiliating Genes
1 hypopyon ulcer 12.0
2 behcet syndrome 10.8
3 uveitis 10.3
4 lens-induced iridocyclitis 10.1 HLA-B MRAP
5 leukemia 10.1
6 plasmodium falciparum malaria 10.1 HLA-B MRAP
7 endophthalmitis 10.1
8 keratitis 10.0
9 infectious anterior uveitis 10.0 HLA-B MRAP
10 anterior uveitis 10.0
11 goodpasture syndrome 10.0 HLA-B MRAP
12 lymphoma 9.9
13 myeloid leukemia 9.9
14 inclusion conjunctivitis 9.9 MRAP NCAM1
15 cryptococcosis 9.9 HLA-B MRAP
16 iritis 9.9
17 corneal ulcer 9.9
18 retinitis 9.8
19 iridocyclitis 9.8
20 acquired immunodeficiency syndrome 9.8
21 relapsing polychondritis 9.8
22 lymphoblastic leukemia 9.8
23 pneumonia 9.7
24 panuveitis 9.7
25 psoriasis 9.7
26 psoriasis susceptibility 1 9.7 HLA-B MRAP
27 retinal vasculitis 9.7
28 spondylitis 9.7
29 scleritis 9.7
30 vasculitis 9.7
31 acute leukemia 9.7
32 arthritis 9.7
33 b-cell lymphomas 9.5
34 leishmaniasis 9.5
35 cataract 9.5
36 band keratopathy 9.5
37 tuberculosis 9.5
38 pemphigus 9.5
39 crohn's disease 9.5
40 orbital cellulitis 9.5
41 intraocular lymphoma 9.5
42 retinal detachment 9.5
43 meningitis 9.5
44 myocardial infarction 9.5
45 keratopathy 9.5
46 astigmatism 9.5
47 systemic lupus erythematosus 9.5
48 sympathetic ophthalmia 9.5
49 haemophilus influenzae 9.5
50 hodgkin lymphoma 9.5

Comorbidity relations with Hypopyon via Phenotypic Disease Network (PDN):


Acute Endophthalmitis Purulent Endophthalmitis

Graphical network of the top 20 diseases related to Hypopyon:



Diseases related to Hypopyon

Symptoms & Phenotypes for Hypopyon

Drugs & Therapeutics for Hypopyon

Drugs for Hypopyon (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Difluprednate Approved Phase 3 23674-86-4 443936
2
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
4
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
5
Natamycin Approved Phase 3 7681-93-8 5281099
6
Povidone Approved Phase 3 9003-39-8
7 Povidone-iodine Approved Phase 3 25655-41-8
8
Tetracaine Approved, Vet_approved Phase 3 94-24-6 5411
9
Iodine Investigational Phase 3 7553-56-2 807
10 Antiemetics Phase 3
11 Anti-Inflammatory Agents Phase 3
12 Antineoplastic Agents, Hormonal Phase 3
13 Autonomic Agents Phase 3
14 Fluprednisolone Phase 3
15 Gastrointestinal Agents Phase 3
16 glucocorticoids Phase 3
17 Hormone Antagonists Phase 3
18 Hormones Phase 3
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
20 Methylprednisolone acetate Phase 3
21 Methylprednisolone Hemisuccinate Phase 3
22 Neuroprotective Agents Phase 3
23 Peripheral Nervous System Agents Phase 3
24 Prednisolone acetate Phase 3
25 Prednisolone hemisuccinate Phase 3
26 Prednisolone phosphate Phase 3
27 Protective Agents Phase 3
28 Anti-Bacterial Agents Phase 3
29 Antifungal Agents Phase 3
30 Anti-Infective Agents Phase 3
31 Anti-Infective Agents, Local Phase 3
32 Blood Substitutes Phase 3
33 cadexomer iodine Phase 3
34 Micronutrients Phase 3
35 Ophthalmic Solutions Phase 3
36 Pharmaceutical Solutions Phase 3
37 Plasma Substitutes Phase 3
38 Trace Elements Phase 3
39 Anesthetics Phase 3
40 Anesthetics, Local Phase 3
41 Central Nervous System Depressants Phase 3

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Aurolab Hydrophobic Foldable Intraocular Lens Study Completed NCT00449267 Phase 4
2 Difluprednate Pediatric Study for the Treatment of Inflammation Post-Cataract Surgery Completed NCT01124045 Phase 3 Difluprednate ophthalmic emulsion, 0.05%;Prednisolone acetate ophthalmic suspension, 1.0%
3 A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine Terminated NCT00516399 Phase 3 povidone-iodine 1.25% ophthalmic solution;natamycin ophthalmic suspension, USP 5%
4 Effect of Tetracaine on Pain Management and Corneal Healing in Patients With Acute Corneal Abrasion Terminated NCT02483897 Phase 3 Tetracaine 0.5% ophthalmic drops;Normal Saline placebo drops

Search NIH Clinical Center for Hypopyon

Genetic Tests for Hypopyon

Anatomical Context for Hypopyon

MalaCards organs/tissues related to Hypopyon:

39
Eye, Myeloid, Testes, T Cells, B Cells, Neutrophil

Publications for Hypopyon

Articles related to Hypopyon:

(show top 50) (show all 191)
id Title Authors Year
1
Inverse Hypopyon. ( 28219502 )
2017
2
In response to: "Ranjan, P, Joshi P, and Gupta M. Staphylococcus aureus induced endogenous endophthalmitis with pink hypopyon." ( 28448724 )
2017
3
Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome. ( 28386497 )
2017
4
Treatment of Epithelial Downgrowth Masquerading as Unilateral Hypopyon Uveitis in a HLA-B27+ Individual. ( 27598054 )
2016
5
Hypopyon uveitis following panretinal photocoagulation. ( 27381997 )
2016
6
Ochrobactrum anthropi Keratitis with Focal Descemet's Membrane Detachment and Intracorneal Hypopyon. ( 27777806 )
2016
7
Inverted hypopyon in the eye. ( 26887888 )
2016
8
Staphylococcus aureus Induced Endogenous Endophthalmitis with Pink Hypopyon. ( 27937098 )
2016
9
Hypopyon complicating the course of anterior uveitis in a patient with Behcet's syndrome. ( 27648274 )
2016
10
IMAGES IN CLINICAL MEDICINE. Hypopyon and Klebsiella Sepsis. ( 27355556 )
2016
11
Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis. ( 26078897 )
2015
12
Intraocular Relapse with Hypopyon and Retinal Infiltrates after Chemotherapy and Peripheral Blood Stem Cell Transplantation for Extranodal NK/T-Cell Lymphoma. ( 26763364 )
2015
13
Unusual presentation of subretinal cysticercosis with hypopyon uveitis. ( 25871533 )
2015
14
Pink hypopyon in a patient with Serratia marcescens corneal ulceration. ( 25861400 )
2015
15
Severe staphylococcal marginal keratitis presenting with hypopyon. ( 26286911 )
2015
16
Medical image. Leukaemic hypopyon. ( 25899495 )
2015
17
A case of panuveitis with hypopyon due to presumed ocular leishmaniasis in a HIV patient. ( 26530344 )
2014
18
Pigmented hypopyon in association with Listeria monocytogenes endopthalmitis: an interesting case report following refractive surgery procedure with literature review. ( 24669144 )
2014
19
When the eye gives it all: diagnosis of relapsing acute myeloblastic leukemia with anterior chamber tap of a chronic hypopyon. ( 25165787 )
2014
20
Alternaria keratitis and hypopyon after clear-cornea phacoemulsification. ( 24461506 )
2014
21
Hypopyon Uveitis Following Panretinal Photocoagulation in a Diabetic Patient. ( 23947383 )
2013
22
'Hypopyon' in the anterior chamber: unilateral ocular relapse of acute myeloid leukaemia in a 2-year-old girl. ( 23750915 )
2013
23
Leukemic hypopyon in acute myeloid leukemia. ( 23225088 )
2013
24
Minimal trephination penetrating keratoplasty for severe fungal keratitis complicated with hypopyon. ( 24314417 )
2013
25
Inverted hypopyon in the posterior pole. ( 23538580 )
2013
26
Bilateral Hypopyon Uveitis Secondary to Mycosis Fungoides with Sezary Syndrome. ( 24131357 )
2013
27
Hypopyon and pseudoendophthalmitis 1 month after vitrectomy for retinal detachment with subretinal hemorrhage. ( 23676232 )
2013
28
Hypopyon as the first sign of relapse in acute lymphoblastic leukaemia. ( 23400411 )
2013
29
Hypopyon uveitis-a rare presentation of intraocular tuberculosis. ( 23617801 )
2013
30
Hypopyon-like features: new dermoscopic criteria in the differential diagnosis of cutaneous lymphangioma circumscriptum and haemangiomas? ( 21645121 )
2012
31
Recurrent anterior uveitis with hypopyon revealing relapsing polychondritis. ( 23154727 )
2012
32
Hypopyon in patients with fungal keratitis. ( 22490405 )
2012
33
Hypopyon uveitis in ankylosing spondylitis. ( 23013851 )
2012
34
Hypopyon in the context of tuberculous uveitis. ( 22229955 )
2012
35
Hypopyon uveitis following LASIK in a patient with ulcerative colitis. ( 22869236 )
2012
36
Rifabutin-associated hypopyon uveitis and retinal vasculitis with a history of acute myeloid leukemia. ( 22311604 )
2012
37
A case of congenital corneal anesthesia with hypopyon in china. ( 22678876 )
2012
38
Hypopyon caused by septic embolisation from valvular endocarditis. ( 21134764 )
2011
39
Anterior segment intraocular metallic foreign body causing chronic hypopyon uveitis. ( 21484173 )
2011
40
Relapsing acute myeloid leukemia presenting as hypopyon uveitis. ( 21836350 )
2011
41
Comment on 'Pink hypopyon caused by Klebsiella pneumonia'. ( 21252947 )
2011
42
Dark hypopyon in Streptococcus bovis endogenous endophthalmitis: clinicopathologic correlations. ( 21475652 )
2011
43
Topiramate-induced bilateral anterior uveitis associated with hypopyon formation. ( 21034312 )
2011
44
Hypopyon in patients with uveitis. ( 20006905 )
2010
45
Pink hypopyon caused by Klebsiella pneumonia. ( 19648890 )
2010
46
Haemorrhagic hypertensive hypopyon uveitis in early immune reactivation uveitis. ( 19407838 )
2010
47
Kinetics of polymorphonuclear leukocytes in an experimental hypopyon model. ( 20723542 )
2010
48
Bilateral uveitis with hypopyon as a presenting symptom of metastatic peritoneal carcinomatosis. ( 20099238 )
2010
49
Hypopyon sign in pemphigus vulgaris and pemphigus foliaceus. ( 19785090 )
2009
50
A head-tilt test for hypopyon after intravitreal triamcinolone. ( 19092731 )
2009

Variations for Hypopyon

Expression for Hypopyon

Search GEO for disease gene expression data for Hypopyon.

Pathways for Hypopyon

Pathways related to Hypopyon according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.78 HLA-B NCAM1

GO Terms for Hypopyon

Cellular components related to Hypopyon according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.26 HLA-B LPIN1 MRAP PITPNM1
2 cytoplasmic ribonucleoprotein granule GO:0036464 8.32 DHX9

Biological processes related to Hypopyon according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 interferon-gamma-mediated signaling pathway GO:0060333 8.62 HLA-B NCAM1

Sources for Hypopyon

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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