Aliases & Classifications for Hypopyon

MalaCards integrated aliases for Hypopyon:

Name: Hypopyon 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10443
ICD10 32 H20.05
ICD9CM 34 364.05
NCIt 46 C50593
SNOMED-CT 64 87807004
UMLS 69 C0020641

Summaries for Hypopyon

MalaCards based summary : Hypopyon is related to iritis and iridocyclitis. An important gene associated with Hypopyon is MRAP (Melanocortin 2 Receptor Accessory Protein). The drugs Difluprednate and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye, myeloid and t cells.

Wikipedia : 72 Hypopyon is a medical condition involving inflammatory cells in the anterior chamber of the... more...

Related Diseases for Hypopyon

Diseases related to Hypopyon via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 iritis 30.0 HLA-B MRAP
2 iridocyclitis 29.9 HLA-B MRAP
3 panuveitis 29.6 HLA-B MRAP
4 spondyloarthropathy 1 29.2 HLA-B MRAP
5 hypopyon ulcer 12.1
6 behcet syndrome 11.0
7 uveitis 10.4
8 leukemia 10.2
9 endophthalmitis 10.2
10 keratitis, hereditary 10.1
11 glaucomatocyclitic crisis 10.1 HLA-B MRAP
12 anterior uveitis 10.1
13 lymphoma 10.1
14 myeloid leukemia 10.0
15 orbital plasma cell granuloma 10.0 MRAP NCAM1
16 corneal ulcer 10.0
17 anterior scleritis 9.9 MRAP NCAM1
18 leukemia, acute myeloid 9.9
19 lymphoblastic leukemia 9.9
20 relapsing polychondritis 9.9
21 retinitis 9.9
22 acquired immunodeficiency syndrome 9.9
23 chronic orbital inflammation 9.9 MRAP NCAM1
24 spondyloarthropathy 9.8 HLA-B MRAP
25 leukemia, chronic myeloid 9.8
26 pustulosis of palm and sole 9.8
27 pneumonia 9.8
28 psoriasis 9.8
29 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.8
30 acute leukemia 9.8
31 arthritis 9.8
32 retinal vasculitis 9.8
33 inflammatory spondylopathy 9.8
34 scleritis 9.8
35 acute closed-angle glaucoma 9.8
36 spondylitis 9.8
37 vasculitis 9.8
38 tuberculous uveitis 9.8
39 systemic lupus erythematosus 9.6
40 pemphigus vulgaris, familial 9.6
41 retinal detachment 9.6
42 corneal dystrophy, band-shaped 9.6
43 lymphoma, hodgkin, classic 9.6
44 leprosy 3 9.6
45 mycosis fungoides 9.6
46 astigmatism 9.6
47 lymphoma, non-hodgkin, familial 9.6
48 psoriatic arthritis 9.6
49 mycobacterium tuberculosis 1 9.6
50 kala-azar 1 9.6

Comorbidity relations with Hypopyon via Phenotypic Disease Network (PDN):


Acute Endophthalmitis Purulent Endophthalmitis

Graphical network of the top 20 diseases related to Hypopyon:



Diseases related to Hypopyon

Symptoms & Phenotypes for Hypopyon

Drugs & Therapeutics for Hypopyon

Drugs for Hypopyon (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Difluprednate Approved Phase 3 23674-86-4 443936
2
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
4
Iodine Approved, Investigational Phase 3 7553-56-2 807
5
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
6
Natamycin Approved Phase 3 7681-93-8 5281099
7
Povidone Approved Phase 3 9003-39-8
8
Povidone-iodine Approved Phase 3 25655-41-8
9
Tetracaine Approved, Vet_approved Phase 3 94-24-6 5411
10 Antiemetics Phase 3
11 Anti-Inflammatory Agents Phase 3
12 Antineoplastic Agents, Hormonal Phase 3
13 Autonomic Agents Phase 3
14 Fluprednisolone Phase 3
15 Gastrointestinal Agents Phase 3
16 glucocorticoids Phase 3
17 Hormone Antagonists Phase 3
18 Hormones Phase 3
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
20 Methylprednisolone acetate Phase 3
21 Methylprednisolone Hemisuccinate Phase 3
22 Neuroprotective Agents Phase 3
23 Peripheral Nervous System Agents Phase 3
24 Prednisolone acetate Phase 3
25 Prednisolone hemisuccinate Phase 3
26 Prednisolone phosphate Phase 3
27 Protective Agents Phase 3
28 Anti-Bacterial Agents Phase 3
29 Antifungal Agents Phase 3
30 Anti-Infective Agents Phase 3
31 Anti-Infective Agents, Local Phase 3
32 Blood Substitutes Phase 3
33 cadexomer iodine Phase 3
34 Micronutrients Phase 3
35 Ophthalmic Solutions Phase 3
36 Pharmaceutical Solutions Phase 3
37 Plasma Substitutes Phase 3
38 Trace Elements Phase 3
39 Anesthetics Phase 3
40 Anesthetics, Local Phase 3
41 Central Nervous System Depressants Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Aurolab Hydrophobic Foldable Intraocular Lens Study Completed NCT00449267 Phase 4
2 Difluprednate Pediatric Study for the Treatment of Inflammation Post-Cataract Surgery Completed NCT01124045 Phase 3 Difluprednate ophthalmic emulsion, 0.05%;Prednisolone acetate ophthalmic suspension, 1.0%
3 A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine Terminated NCT00516399 Phase 3 povidone-iodine 1.25% ophthalmic solution;natamycin ophthalmic suspension, USP 5%
4 Effect of Tetracaine on Pain Management and Corneal Healing in Patients With Acute Corneal Abrasion Terminated NCT02483897 Phase 3 Tetracaine 0.5% ophthalmic drops;Normal Saline placebo drops

Search NIH Clinical Center for Hypopyon

Genetic Tests for Hypopyon

Anatomical Context for Hypopyon

MalaCards organs/tissues related to Hypopyon:

38
Eye, Myeloid, T Cells, Testes, B Cells, Neutrophil

Publications for Hypopyon

Articles related to Hypopyon:

(show top 50) (show all 197)
# Title Authors Year
1
Primary adrenal T-cell lymphoma in a young adult presented with pseudo-hypopyon: a case report and literature review. ( 29043242 )
2017
2
Bilateral Severe Sterile Inflammation with Hypopyon after Simultaneous Intravitreal Triamcinolone Acetonide and Aflibercept Injection in a Patient with Bilateral Marked Rubeosis Associated with Ocular Ischemic Syndrome. ( 28386497 )
2017
3
Inverse Hypopyon. ( 28219502 )
2017
4
Tuberculous uveitis presenting as pigmented hypopyon - A case report. ( 29260068 )
2017
5
Child with hypopyon. ( 29054898 )
2017
6
Bilateral Hypopyon Uveitis in Chronic Myeloid Leukemia. ( 29344492 )
2017
7
Hemorrhagic hypopyon as presenting feature of intravascular lymphoma, a case report. ( 29070018 )
2017
8
Inverse hypopyon (hyperoleon) at the posterior segment in pathological myopia. ( 29183904 )
2017
9
In response to: "Ranjan, P, Joshi P, and Gupta M. Staphylococcus aureus induced endogenous endophthalmitis with pink hypopyon." ( 28448724 )
2017
10
Inverted hypopyon in the eye. ( 26887888 )
2016
11
Ochrobactrum anthropi Keratitis with Focal Descemet's Membrane Detachment and Intracorneal Hypopyon. ( 27777806 )
2016
12
Treatment of Epithelial Downgrowth Masquerading as Unilateral Hypopyon Uveitis in a HLA-B27+ Individual. ( 27598054 )
2016
13
Hypopyon complicating the course of anterior uveitis in a patient with Behcet's syndrome. ( 27648274 )
2016
14
Hypopyon uveitis following panretinal photocoagulation. ( 27381997 )
2016
15
IMAGES IN CLINICAL MEDICINE. Hypopyon and Klebsiella Sepsis. ( 27355556 )
2016
16
Staphylococcus aureus Induced Endogenous Endophthalmitis with Pink Hypopyon. ( 27937098 )
2016
17
Severe staphylococcal marginal keratitis presenting with hypopyon. ( 26286911 )
2015
18
Medical image. Leukaemic hypopyon. ( 25899495 )
2015
19
Cytomegalovirus Uveitis with Hypopyon Mimicking Bacterial Endophthalmitis. ( 26078897 )
2015
20
Intraocular Relapse with Hypopyon and Retinal Infiltrates after Chemotherapy and Peripheral Blood Stem Cell Transplantation for Extranodal NK/T-Cell Lymphoma. ( 26763364 )
2015
21
Unusual presentation of subretinal cysticercosis with hypopyon uveitis. ( 25871533 )
2015
22
Pink hypopyon in a patient with Serratia marcescens corneal ulceration. ( 25861400 )
2015
23
Alternaria keratitis and hypopyon after clear-cornea phacoemulsification. ( 24461506 )
2014
24
A case of panuveitis with hypopyon due to presumed ocular leishmaniasis in a HIV patient. ( 26530344 )
2014
25
Pigmented hypopyon in association with Listeria monocytogenes endopthalmitis: an interesting case report following refractive surgery procedure with literature review. ( 24669144 )
2014
26
When the eye gives it all: diagnosis of relapsing acute myeloblastic leukemia with anterior chamber tap of a chronic hypopyon. ( 25165787 )
2014
27
Leukemic hypopyon in acute myeloid leukemia. ( 23225088 )
2013
28
Inverted hypopyon in the posterior pole. ( 23538580 )
2013
29
Hypopyon uveitis-a rare presentation of intraocular tuberculosis. ( 23617801 )
2013
30
Hypopyon and pseudoendophthalmitis 1 month after vitrectomy for retinal detachment with subretinal hemorrhage. ( 23676232 )
2013
31
'Hypopyon' in the anterior chamber: unilateral ocular relapse of acute myeloid leukaemia in a 2-year-old girl. ( 23750915 )
2013
32
Minimal trephination penetrating keratoplasty for severe fungal keratitis complicated with hypopyon. ( 24314417 )
2013
33
Hypopyon as the first sign of relapse in acute lymphoblastic leukaemia. ( 23400411 )
2013
34
Hypopyon Uveitis Following Panretinal Photocoagulation in a Diabetic Patient. ( 23947383 )
2013
35
Bilateral Hypopyon Uveitis Secondary to Mycosis Fungoides with Sezary Syndrome. ( 24131357 )
2013
36
Hypopyon-like features: new dermoscopic criteria in the differential diagnosis of cutaneous lymphangioma circumscriptum and haemangiomas? ( 21645121 )
2012
37
Hypopyon in patients with fungal keratitis. ( 22490405 )
2012
38
Hypopyon uveitis in ankylosing spondylitis. ( 23013851 )
2012
39
Hypopyon in the context of tuberculous uveitis. ( 22229955 )
2012
40
Hypopyon uveitis following LASIK in a patient with ulcerative colitis. ( 22869236 )
2012
41
Recurrent anterior uveitis with hypopyon revealing relapsing polychondritis. ( 23154727 )
2012
42
A case of congenital corneal anesthesia with hypopyon in china. ( 22678876 )
2012
43
Rifabutin-associated hypopyon uveitis and retinal vasculitis with a history of acute myeloid leukemia. ( 22311604 )
2012
44
Anterior segment intraocular metallic foreign body causing chronic hypopyon uveitis. ( 21484173 )
2011
45
Comment on 'Pink hypopyon caused by Klebsiella pneumonia'. ( 21252947 )
2011
46
Dark hypopyon in Streptococcus bovis endogenous endophthalmitis: clinicopathologic correlations. ( 21475652 )
2011
47
Relapsing acute myeloid leukemia presenting as hypopyon uveitis. ( 21836350 )
2011
48
Hypopyon caused by septic embolisation from valvular endocarditis. ( 21134764 )
2011
49
Topiramate-induced bilateral anterior uveitis associated with hypopyon formation. ( 21034312 )
2011
50
Hypopyon in patients with uveitis. ( 20006905 )
2010

Variations for Hypopyon

Expression for Hypopyon

Search GEO for disease gene expression data for Hypopyon.

Pathways for Hypopyon

GO Terms for Hypopyon

Cellular components related to Hypopyon according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.26 HLA-B LPIN1 MRAP PITPNM1
2 cytoplasmic ribonucleoprotein granule GO:0036464 8.62 DHX9 PITPNM1

Biological processes related to Hypopyon according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interferon-gamma-mediated signaling pathway GO:0060333 8.62 HLA-B NCAM1

Sources for Hypopyon

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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