MCID: HYP226
MIFTS: 25

Hyporeninemic Hypoaldosteronism

Categories: Rare diseases

Aliases & Classifications for Hyporeninemic Hypoaldosteronism

MalaCards integrated aliases for Hyporeninemic Hypoaldosteronism:

Name: Hyporeninemic Hypoaldosteronism 49
Hypoaldosteronism, Hyporeninemic 69
Hypoaldosteronism Hyporeninemic 51

Classifications:



External Ids:

UMLS 69 C0376185

Summaries for Hyporeninemic Hypoaldosteronism

MalaCards based summary : Hyporeninemic Hypoaldosteronism, also known as hypoaldosteronism, hyporeninemic, is related to hypoaldosteronism and hypokalemia. An important gene associated with Hyporeninemic Hypoaldosteronism is REN (Renin), and among its related pathways/superpathways are Peptide hormone metabolism and ACE Inhibitor Pathway, Pharmacodynamics. Affiliated tissues include liver and kidney.

Related Diseases for Hyporeninemic Hypoaldosteronism

Diseases related to Hyporeninemic Hypoaldosteronism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
# Related Disease Score Top Affiliating Genes
1 hypoaldosteronism 32.5 ACE REN
2 hypokalemia 29.7 ACE REN
3 chronic kidney failure 29.6 ACE REN
4 kidney disease 29.5 ACE REN
5 diabetes mellitus 10.2
6 systemic lupus erythematosus 10.2
7 lupus erythematosus 10.2
8 glomerulonephritis 10.1
9 myeloma, multiple 10.1
10 branchiootic syndrome 1 10.1
11 microvascular complications of diabetes 6 10.0
12 amyloidosis 10.0
13 microvascular complications of diabetes 7 10.0
14 sickle cell disease 10.0
15 leukemia, b-cell, chronic 10.0
16 renal tubular acidosis, distal 10.0
17 leukemia 10.0
18 branchiootorenal/branchiootic syndrome 10.0
19 liver cirrhosis 10.0
20 leukemia, chronic lymphocytic 2 10.0
21 renal tubular acidosis 10.0
22 progressive familial heart block, type ia 10.0
23 metabolic acidosis 10.0
24 leukemia, chronic lymphocytic 10.0
25 autonomic neuropathy 10.0
26 nephrotic syndrome 10.0
27 lactic acidosis 10.0
28 diabetes and deafness, maternally inherited 10.0
29 microvascular complications of diabetes 3 10.0
30 neuropathy 10.0
31 microvascular complications of diabetes 4 10.0
32 renal artery obstruction 9.9 ACE REN
33 hypertension, diastolic 9.9 ACE REN
34 atrial septal defect 4 9.9 ACE REN
35 hypertensive retinopathy 9.9 ACE REN
36 orthostatic proteinuria 9.9 ACE REN
37 renal artery disease 9.9 ACE REN
38 malignant essential hypertension 9.9 ACE REN
39 anuria 9.9 ACE REN
40 malignant hypertension 9.9 ACE REN
41 fibromuscular dysplasia 9.9 ACE REN
42 hepatorenal syndrome 9.9 ACE REN
43 renal hypertension 9.9 ACE REN
44 oligohydramnios 9.9 ACE REN
45 renovascular hypertension 9.9 ACE REN
46 pure autonomic failure 9.9 ACE REN
47 renal tubular dysgenesis 9.9 ACE REN
48 ureteral disease 9.9 ACE REN
49 pseudohyperkalemia, familial, 2, due to red cell leak 9.9 ACE REN
50 interstitial nephritis 9.9 ACE REN

Graphical network of the top 20 diseases related to Hyporeninemic Hypoaldosteronism:



Diseases related to Hyporeninemic Hypoaldosteronism

Symptoms & Phenotypes for Hyporeninemic Hypoaldosteronism

Drugs & Therapeutics for Hyporeninemic Hypoaldosteronism

Search Clinical Trials , NIH Clinical Center for Hyporeninemic Hypoaldosteronism

Genetic Tests for Hyporeninemic Hypoaldosteronism

Anatomical Context for Hyporeninemic Hypoaldosteronism

MalaCards organs/tissues related to Hyporeninemic Hypoaldosteronism:

38
Liver, Kidney

Publications for Hyporeninemic Hypoaldosteronism

Articles related to Hyporeninemic Hypoaldosteronism:

(show top 50) (show all 74)
# Title Authors Year
1
Branchio-oto-renal syndrome presenting with syndrome of hyporeninemic hypoaldosteronism. ( 28937080 )
2017
2
Hyporeninemic hypoaldosteronism and diabetes mellitus: Pathophysiology assumptions, clinical aspects and implications for management. ( 26981183 )
2016
3
Paraparesis secondary to hypokalaemia with hyporeninemic hypoaldosteronism during pregnancy: a diagnostic dilemma. ( 27757164 )
2013
4
Maternally-inherited diabetes with deafness (MIDD) and hyporeninemic hypoaldosteronism. ( 23295301 )
2012
5
A case of hyporeninemic hypoaldosteronism in the dog. ( 21696443 )
2011
6
Hyporeninemic hypoaldosteronism in a child with chronic kidney disease--is this condition renoprotective? ( 19189133 )
2009
7
Treatment for hyperkalemia in hyporeninemic hypoaldosteronism. ( 19404283 )
2009
8
Hyporeninemic hypoaldosteronism from secondary amyloidosis. ( 18670413 )
2008
9
Hyporeninemic hypoaldosteronism associated with SjAPgren's syndrome. ( 11893359 )
2002
10
Transient hyporeninemic hypoaldosteronism in acute glomerulonephritis. ( 12432442 )
2002
11
Prerenal azotemia in a diabetic patient with hyporeninemic hypoaldosteronism and autonomic neuropathy. ( 10566125 )
1999
12
Prominent medial hypertrophy of renal arterioles in an infant with hyporeninemic hypoaldosteronism. ( 10353411 )
1999
13
Hyporeninemic hypoaldosteronism in patients with nephrotic syndrome. ( 9627045 )
1998
14
Accidental shock during epidural anesthesia in a patient with NSAID-induced hyporeninemic hypoaldosteronism. ( 9257212 )
1997
15
Reversible hyperkalemia at the initiation of ACE inhibitors in a young diabetic patient with latent hyporeninemic hypoaldosteronism. ( 8799646 )
1996
16
[Diabetic nephropathy and isolated hyporeninemic hypoaldosteronism]. ( 8928409 )
1996
17
A case of isolated ACTH deficiency with hyporeninemic hypoaldosteronism. ( 8773360 )
1996
18
[The effect of long-term treatment of arterial hypertension with Ca antagonists on the renin-angiotensin-aldosterone system in diabetics. Hyporeninemic hypoaldosteronism]. ( 8578695 )
1995
19
Mechanisms of hyperkalemia associated with hyporeninemic hypoaldosteronism in streptozotocin-induced diabetic rats. ( 7986385 )
1994
20
Hyperkalemia due to hyporeninemic hypoaldosteronism with liver cirrhosis and hypertension. ( 8179835 )
1993
21
Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus. ( 8336514 )
1993
22
Hyporeninemic hypoaldosteronism associated with multiple myeloma: 11 years of follow-up. ( 8222376 )
1993
23
Hyporeninemic hypoaldosteronism complicating primary autonomic insufficiency. ( 8212689 )
1993
24
[A case of hyporeninemic hypoaldosteronism improved by dexamethasone treatment]. ( 1607144 )
1992
25
Hyperkalemia in acute glomerulonephritis due to transient hyporeninemic hypoaldosteronism. ( 2074657 )
1990
26
Reversible hyporeninemic hypoaldosteronism in a patient with tetraplegia. ( 2543544 )
1989
27
Hyporeninemic hypoaldosteronism in diabetic patients with chronic renal failure. ( 3394721 )
1988
28
Hyporeninemic hypoaldosteronism presenting with hypokalemia. ( 3281049 )
1988
29
Primary role of hyperkalemia in the acidosis of hyporeninemic hypoaldosteronism. ( 3398981 )
1988
30
Liddle's syndrome, an uncommon form of hyporeninemic hypoaldosteronism: functional and histopathological studies. ( 3550146 )
1987
31
Hyperkalemic distal renal tubular acidosis with hyporeninemic hypoaldosteronism in a patient with systemic lupus erythematosus--a case report. ( 3441801 )
1987
32
Hyporeninemic hypoaldosteronism associated with acquired immune deficiency syndrome. ( 3555065 )
1987
33
Hyporeninemic hypoaldosteronism in a patient with cirrhosis and ascites. ( 3535721 )
1986
34
Hyporeninemic hypoaldosteronism in children with chronic renal failure. ( 3528445 )
1986
35
Hyporeninemic hypoaldosteronism. ( 3515186 )
1986
36
Evidence of prostacyclin deficiency in the syndrome of hyporeninemic hypoaldosteronism. ( 3515183 )
1986
37
Systemic lupus erythematosus presenting with hyporeninemic hypoaldosteronism in a 10-year-old girl. ( 3535507 )
1986
38
Hyperkalemic left bundle branch block and hyporeninemic hypoaldosteronism (hyperkalemic left bundle branch block). ( 3543195 )
1986
39
Pseudo-Addison's disease. Isolated corticotropin deficiency associated with hyporeninemic hypoaldosteronism. ( 3008682 )
1986
40
Studies of renin activation and regulation of aldosterone and 18-hydroxycorticosterone biosynthesis in hyporeninemic hypoaldosteronism. ( 2987296 )
1985
41
Hyporeninemic hypoaldosteronism. New associations. ( 3896183 )
1985
42
IgM monoclonal gammopathy accompanied by nodular glomerulosclerosis, urine-concentrating defect, and hyporeninemic hypoaldosteronism. ( 3918448 )
1985
43
The syndrome of hyporeninemic hypoaldosteronism. ( 6387040 )
1984
44
Hyporeninemic hypoaldosteronism in a patient with multiple myeloma. ( 6383030 )
1984
45
Hyporeninemic hypoaldosteronism in two patients with systemic lupus erythematosus. ( 6377883 )
1984
46
Hyporeninemic hypoaldosteronism in infancy: a familial disease. ( 6315756 )
1984
47
Hyporeninemic hypoaldosteronism, sodium wasting and mineralocorticoid-resistant hyperkalemia in two patients with obstructive uropathy. ( 6351617 )
1983
48
Hyporeninemic hypoaldosteronism in infancy. ( 6353255 )
1983
49
Hyporeninemic hypoaldosteronism in sickle cell disease. ( 6750423 )
1982
50
Renal acidification in hyporeninemic hypoaldosteronism. ( 15171017 )
1982

Variations for Hyporeninemic Hypoaldosteronism

Expression for Hyporeninemic Hypoaldosteronism

Search GEO for disease gene expression data for Hyporeninemic Hypoaldosteronism.

Pathways for Hyporeninemic Hypoaldosteronism

GO Terms for Hyporeninemic Hypoaldosteronism

Biological processes related to Hyporeninemic Hypoaldosteronism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.26 ACE REN
2 regulation of blood pressure GO:0008217 9.16 ACE REN
3 amyloid-beta metabolic process GO:0050435 8.96 ACE REN
4 angiotensin maturation GO:0002003 8.62 ACE REN

Molecular functions related to Hyporeninemic Hypoaldosteronism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 8.96 ACE REN
2 endopeptidase activity GO:0004175 8.62 ACE REN

Sources for Hyporeninemic Hypoaldosteronism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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