MCID: HYP040
MIFTS: 57

Hypospadias malady

Categories: Genetic diseases, Rare diseases, Reproductive diseases, Fetal diseases

Aliases & Classifications for Hypospadias

About this section
Sources:
11Disease Ontology, 13DISEASES, 26GTR, 29ICD10, 30ICD10 via Orphanet, 38MeSH, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS
See all MalaCards sources

Aliases & Descriptions for Hypospadias:

Name: Hypospadias 11 26 49 38 13
Familial Hypospadias 11 53
 
Hypospadias Familial 47

Characteristics:

Orphanet epidemiological data:

53
familial hypospadias:
Inheritance: Autosomal dominant,Autosomal recessive,X-linked recessive; Age of onset: Infancy,Neonatal; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:10892
ICD1029 Q54, Q54.9
MeSH38 D007021
SNOMED-CT61 416010008
NCIt44 C40341
Orphanet53 ORPHA440
ICD10 via Orphanet30 Q54.0, Q54.1, Q54.2 Q54.3, Q54.4, Q54.8, Q54.9, more
UMLS67 C0848558

Summaries for Hypospadias

About this section
Disease Ontology:11 A physical disorder characterized by an abnormally placed urethral opening on the underside of the penis or on the perineum.

MalaCards based summary: Hypospadias, also known as familial hypospadias, is related to hypospadias 1, x-linked and mixed gonadal dysgenesis, and has symptoms including displacement of the external urethral meatus and Array. An important gene associated with Hypospadias is MAMLD1 (Mastermind Like Domain Containing 1), and among its related pathways are Steroid hormone biosynthesis and Metabolism of steroid hormones. Affiliated tissues include skin, testis and pituitary, and related mouse phenotypes are muscle and renal/urinary system.

Wikipedia:70 Hypospadias /haɪpoʊˈspeɪdɪəs/ is a birth abnormality of the urethra where the urinary opening is... more...

Related Diseases for Hypospadias

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Diseases in the Hypospadias family:

Hypospadias 3, Autosomal Posterior Hypospadias

Diseases related to Hypospadias via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 149)
idRelated DiseaseScoreTop Affiliating Genes
1hypospadias 1, x-linked33.5AR, MAMLD1, NR5A1, SRD5A2, SRY
2mixed gonadal dysgenesis29.6NR5A1, SRY, WT1
3pseudovaginal perineoscrotal hypospadias12.2
4hypospadias 2, x-linked12.1
5posterior hypospadias12.0
6hypospadias-mental retardation syndrome11.9
7radial hypoplasia, triphalangeal thumbs, hypospadias, and maxillary diastema11.9
8hypospadias, hypertelorism, upper lid coloboma, and mixed-type hearing loss11.8
9hypospadias mental retardation goldblatt type11.8
10opitz gbbb syndrome, type ii11.8
11hypospadias 3, autosomal11.7
12hypospadias 4, x-linked11.7
13hypotelorism cleft palate hypospadias11.7
14radial hypoplasia, triphalangeal thumbs and hypospadias11.7
15spina bifida hypospadias11.7
16anal atresia, hypospadias, and penoscrotal inversion11.6
17deafness hypospadias metacarpal and metatarsal syndrome11.6
18myopathy growth and mental retardation hypospadias11.6
19tracheophageal fistula hypospadias11.6
20myopathy-growth delay-intellectual disability-hypospadias syndrome11.6
21tracheo-esophageal fistula-hypospadias syndrome11.6
22lower limb deficiency-hypospadias syndrome11.6
23spondylocostal dysostosis-hypospadias-intellectual disability syndrome11.6
24guttmacher syndrome11.5
25opitz gbbb syndrome, type i11.5
26schmitt gillenwater kelly syndrome11.4
275-alpha reductase deficiency11.2
28androgen insensitivity11.1
29mowat-wilson syndrome11.0
30leydig cell hypoplasia with pseudohermaphroditism10.9
31androgen insensitivity, partial, with or without breast cancer10.9
32acrofrontofacionasal dysostosis 210.8
33steroid 5-alpha-reductase deficiency10.8
34testicular anomalies with or without congenital heart disease10.7
35chromosome 19q13.11 deletion syndrome10.7
36abruzzo-erickson syndrome10.7
37hand-foot-uterus syndrome10.7
38goldberg-shprintzen megacolon syndrome10.7
39proud syndrome10.7
4046,xx testicular disorder of sex development10.7
41pfeiffer kapferer syndrome10.7
42say carpenter syndrome10.7
43familial interstitial fibrosis10.6SRD5A1, SRD5A2
44leukorrhea10.5AR, SRD5A2, SRY
45gastrojejunal ulcer10.5AR, CYP17A1, SRD5A2
46myelodysplasia and leukemia syndrome with monosomy 710.5HOXA13, HOXD13
47epilepsy, idiopathic generalized 1110.5AR, SRD5A1, SRD5A2
48myoclonic cerebellar dyssynergia10.5AR, HSD17B3, SRY
49tetraamelia with pulmonary hypoplasia10.5NR5A1, SRY
50urethritis10.5

Graphical network of the top 20 diseases related to Hypospadias:



Diseases related to hypospadias

Symptoms for Hypospadias

About this section

Human phenotypes related to Hypospadias:

 63 53
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 displacement of the external urethral meatus63 hallmark (90%) HP:0100627
2 hypospadias53 Very frequent (99-80%)

Drugs & Therapeutics for Hypospadias

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Drugs for Hypospadias (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 127)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
RopivacaineapprovedPhase 474184057-95-471273, 175805
Synonyms:
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
(S)-(−)-1-propyl-2',6'-pipecoloxylidide
(S)-ropivacaine
84057-95-4
98717-15-8
AC1L41QM
AC1L41QN
BIDD:GT0203
C07532
C17H26N2O.HCl
CHEBI:8890
CHEMBL1077896
CID175804
CID175805
CPD000469137
D08490
I14-176
L-N-n-propylpipecolic acid-2,6-xylidide
LS-113954
 
MLS001401363
MolPort-003-983-292
NCGC00164597-01
Naropin
Naropin (TN)
ROPIVACAINE HCl
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
Ropivacaine [INN]
Ropivacaine hydrochloride
Ropivacaine monohydrochloride
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
SAM001246524
SMR000469137
ST51051452
ropivacaine monohydrochloride,
ropivacaine monohydrochloride, (S)-isomer
2
Dexmedetomidineapproved, vet_approvedPhase 4, Phase 354076631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
3Neurotransmitter AgentsPhase 4, Phase 2, Phase 317734
4AnestheticsPhase 4, Phase 2, Phase 39001
5Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 322776
6Adrenergic AgentsPhase 4, Phase 2, Phase 35140
7Adrenergic alpha-AgonistsPhase 4, Phase 2, Phase 31625
8Adrenergic AgonistsPhase 4, Phase 2, Phase 32877
9AnalgesicsPhase 4, Phase 2, Phase 311287
10Central Nervous System DepressantsPhase 4, Phase 2, Phase 312806
11Adrenergic alpha-2 Receptor AgonistsPhase 4, Phase 3, Phase 2911
12Analgesics, Non-NarcoticPhase 4, Phase 36260
13Hypnotics and SedativesPhase 4, Phase 3, Phase 22485
14Anesthetics, LocalPhase 4, Phase 2, Phase 33272
15
Epinephrineapproved, vet_approvedPhase 2, Phase 393351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
16
Neostigmineapproved, vet_approvedPhase 2, Phase 39959-99-44456
Synonyms:
(m-Hydroxyphenyl)trimethylammonium dimethylcarbamate
(m-Hydroxyphenyl)trimethylammonium dimethylcarbamate (ester)
114-80-7 (bromide)
3-Trimethylammoniumphenyl N,N-dimethylcarbamate
3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium
3-{[(dimethylamino)carbonyl]oxy}-N,N,N-trimethylanilinium
51-60-5 (methyl sulfate)
59-99-4
AB00053807
AC1L1I7G
Ammonium, (m-hydroxyphenyl)trimethyl-, dimethylcarbamate (ester)
BPBio1_000634
BRD-K18922609-004-04-1
BRN 3615946
BSPBio_000576
Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl- (9CI)
C07258
CAS-114-80-7
CCRIS 3079
CHEBI:7514
CID4456
D08261
DB01400
DivK1c_000165
DivK1c_000198
Eustigmin
Eustigmine
HMS2089A22
HSDB 3921
IDI1_000165
IDI1_000198
InChI=1/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1
Intrastigmina
Juvastigmin
KBio1_000165
KBio1_000198
KBio2_001541
KBio2_004109
KBio2_006677
KBioGR_000623
KBioSS_001541
LS-18452
Lopac-N-2001
 
Lopac0_000816
NCGC00015730-01
NCGC00015730-02
NCGC00015730-03
NCGC00015730-04
NCGC00015730-08
NCGC00021658-03
NCGC00163240-01
NEOSTIGMINE
NINDS_000165
NINDS_000198
Neostigmin
Neostigmine (BAN)
Neostigmine [BAN]
Neostigmine omega
Neostigminum
Prestwick0_000468
Prestwick1_000468
Prestwick2_000468
Prestwick3_000468
Prostigmin
Prostigmin (TN)
Prostigmine
Prozerin
SPBio_001276
SPBio_002515
STL058953
Spectrum2_001278
Spectrum4_000072
Spectrum5_001234
Spectrum_001061
Synstigmin
Syntostigmine
UNII-3982TWQ96G
Vagostigmin
Vagostigmine
ZINC00001792
[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium
[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium bromide
[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium
bmse000762
m-Trimethylammoniumphenyldimethylcarbamate
nchembio.188-comp33
sulfonatooxymethane
17
Isofluraneapproved, vet_approvedPhase 2, Phase 316526675-46-73763
Synonyms:
1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether
1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether
2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane
26675-46-7
AC-154802
AC1L1GNN
AErrane (Veterinary)
Aerrane
BRN 1852087
C07518
CCRIS 3043
CHEBI:6015
CHEMBL1256
CID3763
Compound 469
D00545
D007530
DB00753
EINECS 247-897-7
Ethane
Ether, 1-chloro-2,2,2-trifluoroethyl difluoromethyl
 
Forane
Forane (TN)
Forene
I14-1303
IsoFlo
Isoflurane
Isoflurane (JP15/USP/INN)
Isoflurane [Anaesthetics, volatile]
Isoflurane [USAN:BAN:INN:JAN]
Isoflurane [USAN:INN:BAN:JAN]
Isoflurane [Usan:Ban:Inn:Jan]
Isoflurano
Isoflurano [INN-Spanish]
Isofluranum
Isofluranum [INN-Latin]
Jsp005223
LS-7462
MolPort-000-153-606
NCGC00181037-01
R-E 235dal
ST51041445
UNII-CYS9AKD70P
isoflurane
18
Fentanylapproved, illicit, investigational, vet_approvedPhase 2, Phase 3773437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
1-phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl CII
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
Fentanyl-12
Fentanyl-25
 
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidyl)propionanilide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenethyl-4-(N-propionylanilino)piperidine
N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
UNII-UF599785JZ
fentanyl
19
Nitrous oxideapproved, vet_approvedPhase 2, Phase 317010024-97-2948
Synonyms:
00583_FLUKA
10024-97-2
126386-65-0
129451-49-6
130835-71-1
147527-07-9
175876-44-5
295590_ALDRICH
794457-85-5
847968-13-2
850203-00-8
AC1L1ADZ
C00887
CCRIS 1225
CHEBI:17045
CHEMBL1234579
CID948
D00102
D009609
Diazyne 1-oxide
Dinitrogen monoxide
Dinitrogen oxide
Distickstoffmonoxid
E942
EINECS 233-032-0
FEMA 2779
FEMA No. 2779
Factitious air
Gas, Laughing
Gas, laughing
Gaz hilarant
HSDB 504
Hyponitrous acid anhydride
LS-7622
Lachgas
Laughing gas
N2O
NITROUS-OXIDE
NNO
 
Nitral
Nitrious oxide
Nitrogen hypoxide
Nitrogen monoxide
Nitrogen oxide (N2O)
Nitrogen protoxide
Nitrogenium oxydulatum
Nitrous oxide
Nitrous oxide (JP15/USP)
Nitrous oxide (TN)
Nitrous oxide [Anaesthetics, volatile]
Nitrous oxide [JAN]
Nitrous oxide [UN1070] [Nonflammable gas]
Nitrous oxide [UN1070] [Nonflammable gas]
Nitrous oxide [anaesthetics, volatile]
Nitrous oxide [jan]
Nitrous oxide, JAN, USAN
Nitrous oxide, compressed
Nitrous oxide, refrigerated liquid
Nitrous oxide, refrigerated liquid [UN2201] [Nonflammable gas]
Nitrous oxide, refrigerated liquid [UN2201] [Nonflammable gas]
Nitrous-oxide
Oxide, Nitrous
Oxide, nitrous
Oxido nitroso
Oxido nitroso [Spanish]
Oxidodinitrogen(N--N)
Oxyde nitreux
Protoxyde d'azote [French]
Stickdioxyd
Stickdioxyd [German]
Stickstoff(I)-oxid
UN1070
UN2201
gaz hilarant
nitrogenium oxydulatum
nitrous oxide
oxidodinitrogen(N--N)
oxyde nitreux
protoxyde d'azote
20
Midazolamapproved, illicitPhase 368459467-70-84192
Synonyms:
4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate
59467-70-8
8-Chlor-6-(2-fluorphenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepin
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride
8-Chloro-6-(O-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]-benzodiazepine
8-Chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine
AC-18749
AC1L1HMA
BIDD:GT0647
BRN 0625572
Buccolam
C07524
C18H13ClFN3
CHEMBL655
CID4192
D00550
DB00683
DEA No. 2884
Dazolam
Dea No. 2884
 
Dormicum
Dormicum (TN)
EINECS 261-774-5
LS-77780
Midanium
Midazolam
Midazolam (JAN/INN)
Midazolam Base
Midazolam Hcl
Midazolam [INN:BAN:JAN]
Midazolamum
Midazolamum [INN-Latin]
Midosed
MolPort-003-849-219
NCGC00168254-01
Ro 21-3981
TL8003787
UC429_SIGMA
UNII-R60L0SM5BC
Versed
ZINC00001732
midazolam
nchembio747-comp32
21
Bupivacaineapproved, investigationalPhase 2, Phase 311312180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
22
Atropineapproved, vet_approvedPhase 2, Phase 31295908-99-6, 51-55-8174174
Synonyms:
(+,-)-Tropyl tropate
(+-)-Atropine
(+-)-Hyoscyamine
(+-)-atropine
(+-)-hyoscyamine
(+/-)-Atropine
(+/-)-Hyoscyamine
(3-Endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
(3-endo)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
(3-endo,8-syn)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane
(3-exo)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
(±)-atropine
(±)-hyoscyamine
1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester)
1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester) (8CI)
120-29-6
1alphaH,5alphaH-Tropan-3alpha-ol
1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester)
1alphaH,5alphaH-Tropan-3beta-ol
2-Phenylhydracrylic acid 3-alpha-tropanyl ester
51-55-8
8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate
8-Methyl-8-azabicyclo[3.2.1]oct-3-yl tropate
8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropionate
A0132_SIGMA
A2468_SIGMA
AC1L5AX3
AC1Q3XL2
ACon1_000046
AI3-60219
AKOS005137976
ATROPINE
Ambap120-29-6
Anaspaz
Atropair
Atropen
Atropen (TN)
Atropin
Atropin [German]
Atropin-flexiolen
Atropina
Atropina [Italian]
Atropine
Atropine (USP)
Atropine Care
Atropine Sulfate
Atropine Sulfate S.O.P.
Atropine [BAN]
Atropinol
Atropinum
Atropt
Atrosulf
BRD-A27290375-001-01-8
Belladenal
Bellergal-S
Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
C01479
C17H23NO3
CAS-120-29-6
CCRIS 3080
CHEBI:15742
CHEBI:15884
CHEBI:16684
CHEBI:537621
CHEBI:57858
CHEMBL1235490
 
CID174174
CPD001906768
Cytospaz
D00113
DB00572
DB04026
DL-Hyoscyamine
DL-Tropanyl 2-hydroxy-1-phenylpropionate
DL-Tropyl tropate
EINECS 200-104-8
Eyesules
FT-0082634
HMS2089A16
HSDB 2199
Hyoscyamine sulfate
I-Tropine
Isopto Atropine
Isopto-atropine
LS-7203
MEGxp0_001878
MLS000069795
MLS001148094
MLS002695888
Minims
Minims Atropine
MolPort-001-742-593
MolPort-003-986-158
Mydriasine
NCGC00016370-01
NCGC00142514-01
NCGC00142514-03
NP-010662
Neo-Diophen
OR22908
Ocu-Tropine
Protamine & Atropine
SAM002554885
SMR000058248
ST057178
ST057655
T0534
TL8000018
Tropanol
Tropic acid, 3-alpha-tropanyl ester
Tropic acid, ester with tropine
Tropine (+/-)-tropate
Tropine tropate
Tropine, tropate (ester)
Troyl tropate
Urised
[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate
[(1S,5R)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-hydroxy-2-phenyl-propanoate
[(1S,5R)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-hydroxy-2-phenyl-propanoate
a-Tropine
atropinium cation
atropinium(1+)
b eta-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
beta-Phenyl-gamma-oxypropionsaeure-tropyl-ester [German]
beta-Phenyl-gamma-oxypropionsaure-tropyl-ester [German]
bmse000649
d1-hyoscyamine
dl-Hyoscyamine
dl-Tropyltropate
dl-tropyltropate
endo-(+/-)-alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
endo-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
hyoscyamine
nchembio.307-comp21
tropan-3alpha-ol
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate
tropan-3beta-ol
23
Thiopentalapproved, vet_approvedPhase 2, Phase 33576-75-53000715
Synonyms:
()Thiopental solution
(+-)-Thiopental
(+/-)-THIOPENTAL
(+/-)Thiopental solution
2-Thio-5-ethyl-5-sec-pentylbarbituric acid
4,6,(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-(1-methylbutyl)-2-thioxo- (9CI)
5-24-09-00172 (Beilstein Handbook Reference)
5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dione
5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid
5-ethyl-2-mercapto-5-(1-methylbutyl)pyrimidine-4,6(1H,5H)-dione
5-ethyl-5-(1-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione
59709-53-4
76-75-5
AC-16029
AC1MHDBY
AC1Q2UJN
BRD-A72603112-236-02-4
BRN 0209361
BSPBio_003301
Bitaryl
C07521
C11H18N2O2S
CHEBI:102166
CHEMBL441
CID3000715
DB00599
DivK1c_000993
EINECS 200-984-3
I14-14129
IDI1_000993
Intraval
KBio1_000993
KBio2_002272
KBio2_004840
 
KBio2_007408
KBio3_002803
KBioGR_001010
KBioSS_002273
LS-24395
NCGC00159524-01
NINDS_000993
Omexolon
Penthiobarbital
Pentothal
Pentothiobarbital
SPBio_002215
Sodium Pentothal
Spectrum2_001998
Spectrum3_001781
Spectrum4_000575
Spectrum5_001692
Spectrum_001786
T1019_SIGMA
T1022_FLUKA
T1022_SIGMA
Thiomebumal
Thiomebumalum
Thionembutal
Thiopental
Thiopental [BAN]
Thiopentobarbital
Thiopentobarbitone
Thiopentobarbituric acid
Thiopentone
Thiothal
Tiopentale
Tiopentale [Italian]
Trapanal
UNII-JI8Z5M7NA3
thiopental
24
Testosteroneapproved, investigationalPhase 354658-22-06013
Synonyms:
(+)-testosterone
(+-)-8-iso-testosterone
(+-)-retrotestosterone
(+-)-testosterone
(17b)-17-hydroxy-androst-4-en-3-one
(17beta)-17-Hydroxyandrost-4-en-3-one
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
13-Iso-testosterone
17-Hydroxy-(17-beta)-androst-4-en-3-one
17-Hydroxy-(17beta)-androst-4-en-3-one
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
17-Hydroxy-D4-androsten-3-one
17-Hydroxy-androst-4-en-3-one
17-beta-Hydroxy-delta(sup 4)-androsten-3-one
17-beta-Hydroxyandrost-4-en-3-one
17?-Hydroxy-4-androsten-3-one
17a-Hydroxy-(13a)-androst-4-en-3-one
17a-Hydroxy-13a-androst-4-en-3-one
17a-Hydroxy-14b-androst-4-en-3-one
17a-Hydroxy-androst-4-en-3-one
17b-Hydroxy-(10a)-androst-4-en-3-one
17b-Hydroxy-(13a)-androst-4-en-3-one
17b-Hydroxy-(8a)-androst-4-en-3-one
17b-Hydroxy-(8a,10a)-androst-4-en-3-one
17b-Hydroxy-(9b)-androst-4-en-3-one
17b-Hydroxy-(9b,10a)-androst-4-en-3-one
17b-Hydroxy-13a-androst-4-en-3-one
17b-Hydroxy-8a-androst-4-en-3-one
17b-Hydroxy-D4-androsten-3-one
17b-Hydroxy-androst-4-en-3-on
17b-Hydroxy-androst-4-en-3-one
17b-Hydroxyandrost-4-en-3-one
17b-Hydroxyandrost-4-ene-3-one
17b-Testosterone
17b-hydroxy-4-androsten-3-one
17beta-Hydroxy-3-oxo-4-androstene
17beta-Hydroxy-4-androsten-3-one
17beta-Hydroxy-delta(sup4)-androsten-3-one
17beta-Hydroxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-ene-3-one
17beta-hydroxy-4-androsten-3-one
4-Androsten-17?-ol-3-one
4-Androsten-17beta-ol-3-one
4-Androsten-3-one-17b-ol
4-androsten-17β-ol-3-one
4-androstene-17beta-ol-3-one
46923_FLUKA
46923_RIEDEL
58-22-0
7-beta-Hydroxyandrost-4-en-3-one
8-Iso-testosterone
9b,10a-Testosterone
9b-Testosterone
AA 2500
AC-14899
AC1L1LM0
Andriol
Andro
Andro 100
Andro L.A. 200
AndroGel
Androderm
Androderm (TN)
Androgel
Androgel (TN)
Android 10
Android 25
Android 5
Androlin
Andronaq
Andronate 100
Andronate 200
Andropatch
Andropository 200
Androsorb
Androst-4-en-17b-ol-3-one
Androst-4-en-17beta-ol-3-one
Androst-4-ene-17b-ol-3-one
Andrusol
Andryl 200
B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E
BIDD:ER0555
BIM-0061761.0001
Beta Testosterone
Bio-0678
Bio-T-Gel
C00535
CCRIS 574
CDB 111C
CHEBI:17347
CHEMBL386630
CID6013
CMC_13449
COL 1621
CP 601B
CPD000058344
Cristerona T
Cristerone T
D00075
D4-Androsten-17b-ol-3-one
DB00624
Dea No. 4000
Delatest
Delatestryl
Depo-Testadiol
Depo-Testosterone
Depo-Testosterone Cypionate
Depotest
EINECS 200-370-5
Epitestosteron
Everone 200
Geno-Cristaux Gremy
Geno-cristaux Gremy
Geno-cristaux gremy
HMS2052N11
HSDB 3398
Halotensin
Homosteron
Homosterone
 
Intrinsa
LMST02020002
LS-148813
LibiGel
Libigel
Lumitestosteron
MLS000563091
MLS001032098
MLS001306401
MLS002174283
Malerone
Malestrone
Malestrone (amps)
Malogen in Oil
Malogen, Aquaspension Injection
Malogen, aquaspension injection
Mertestate
Metandren
Methyltestosterone
MolPort-002-506-901
NCGC00091018-01
NSC 9700
Neo-Hombreol F
Neo-Testis
Neo-testis
Neotestis
Oreton
Oreton F
Oreton Methyl
Oreton-F
Orquisteron
Perandren
Percutacrine Androgenique
Percutacrine androgenique
Primotest
Primoteston
Rac-17b-hydroxy-(13a)androst-4-en-3-one
Rac-17b-hydroxy-(8a)-androst-4-en-3-one
Rac-17b-hydroxy-(9b,10a)androst-4-en-3-one
Rac-17b-hydroxy-androst-4-en-3-one
Relibra
Retrotestosterone
S00309
S2033_Selleck
SAM001246921
SMR000058344
SMR001261453
Scheinpharm Testone-Cyp
Striant
Striant (TN)
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
T1500_SIGMA
T5411_FLUKA
T5411_SIGMA
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testiculosterone
Testim
Testim (TN)
Testobase
Testoderm
Testoderm Tts
Testogel
Testoject-50
Testolent
Testolin
Testopel Pellets
Testopropon
Testosteroid
Testosteron
Testosterona
Testosterona [INN-Spanish]
Testosterone
Testosterone (JAN/USP)
Testosterone Cypionate
Testosterone Enanthate
Testosterone Hydrate
Testosterone [Androgenic steroids, anabolic]
Testosterone [INN:BAN]
Testosterone and its esters
Testosterone hydrate
Testosterone solution
Testosteronum
Testosteronum [INN-Latin]
Testostosterone
Testostérone
Testoviron
Testoviron Schering
Testoviron T
Testoxyl
Testred
Testred Cypionate 200
Testrin-P.A
Testro AQ
Testro Aq
Testrone
Testryl
Tostrelle
Tostrex
Trans-Testosterone
UNII-3XMK78S47O
Viatrel
Virilon
Virilon IM
Virormone
Virosterone
ZINC06500184
beta testosterone
delta(sup 4)-Androsten-17(beta)-ol-3-one
delta4-Androsten-17beta-ol-3-one
delta4-androsten-17b-ol-3-one
testosterone
trans-Testosterone
25
Estradiolapproved, investigational, vet_approvedPhase 3128350-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol [USAN:INN]
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
Estrofem Forte
Estrogel
 
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
26
MethyltestosteroneapprovedPhase 354658-18-46010
Synonyms:
17(alpha)-Methyl-delta(4)-androsten-17(beta)-ol-3-one
17-Methyltestosterone
17-beta-Hydroxy-17-methylandrost-4-en-3-one
17-methyltestosterone
17alpha-Methyl-3-oxo-4-androsten-17beta-ol
17alpha-Methyl-delta(4)-androsten-17beta-ol-3-one
17alpha-Methyltestosterone
17alpha-methyl-delta-androsten-17beta-ol-3-one
17alpha-methyltestosterone
 
17beta-Hydroxy-17-methylandrost-4-en-3-one
17α-methyl-Δ4-androsten-17β-ol-3-one
17α-methyltestosterone
4-Androstene-17alpha-methyl-17beta-ol-3-one
Android
Methyltestosterone
Methyltestosteronum
Metiltestosterona
NSC-9701
Testred
Virilon
27
Progesteroneapproved, vet_approvedPhase 353757-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14
28
Folic Acidapproved, nutraceutical, vet_approvedPhase 3427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
29Vitamin B ComplexPhase 34229
30MydriaticsPhase 2, Phase 3763
31VitaminsPhase 35095
32Trace ElementsPhase 35802
33MicronutrientsPhase 35802
34HematinicsPhase 31630
35Vasoconstrictor AgentsPhase 2, Phase 32027
36Epinephryl boratePhase 2, Phase 3933
37Respiratory System AgentsPhase 2, Phase 34818
38RacepinephrinePhase 2, Phase 3933
39Adrenergic beta-AgonistsPhase 2, Phase 31640
40Bronchodilator AgentsPhase 2, Phase 32856
41Autonomic AgentsPhase 2, Phase 39774
42Anti-Asthmatic AgentsPhase 2, Phase 33369
43Anti-Arrhythmia AgentsPhase 2, Phase 32969
44Adjuvants, AnesthesiaPhase 2, Phase 31588
45Anesthetics, IntravenousPhase 2, Phase 32406
46Analgesics, OpioidPhase 2, Phase 33091
47Pharmaceutical SolutionsPhase 2, Phase 37793
48
AtracuriumPhase 2, Phase 38064228-79-147319
Synonyms:
2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]
5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
64228-79-1
64228-81-5 (besylate)
AB00514743
AC1L2HUF
AC1Q67HR
Atracurium
Atracurium Dibesylate
BPBio1_000011
BRN 1523633
BSPBio_000009
 
C07548
C53H70N2O12
CHEBI:2914
CHEMBL1360
CID47319
DB00732
HMS2090I21
LS-86151
MolPort-005-932-641
Prestwick1_000005
Prestwick2_000005
Prestwick3_000005
SPBio_001930
UNII-2GQ1IRY63P
49Cholinergic AntagonistsPhase 2, Phase 31658
50ParasympatholyticsPhase 2, Phase 31050

Interventional clinical trials:

(show all 43)
idNameStatusNCT IDPhase
1Pudendal Block Versus Caudal Block for HypospadiasCompletedNCT02390388Phase 4
2Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile SurgeryNot yet recruitingNCT02848157Phase 4
3Folic Acid Dosage and Malformations ReductionUnknown statusNCT01244347Phase 3
4Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias RepairCompletedNCT02752308Phase 2, Phase 3
5Dexmedetomidine Infusion in Hypospadias SurgeryCompletedNCT00926705Phase 3
62-octyl Cyanoacrylate for Closure of Urethrocutaneous Fistula.CompletedNCT02115191Phase 3
7Study Comparing the Polyurethane Films and Sugarcane Biopolymer Used as DressingsCompletedNCT02531828Phase 3
8Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post-operative ComplicationsRecruitingNCT01370798Phase 3
9A Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Crinone 8% Intravaginal Progesterone Gel 90 mg Daily for Luteal Support in In-Vitro Fertilization (LOTUS II)Active, not recruitingNCT02491437Phase 3
10Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz SyndromeUnknown statusNCT00004347Phase 2
11Association of Different Doses of Clonidine in Caudal Epidural Anesthesia for Hypospadias SurgeryCompletedNCT02769390Phase 2
12Treatment of the Cholesterol Defect in Smith-Lemli-Opitz SyndromeCompletedNCT00272844Phase 1, Phase 2
13Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00114634Phase 2
14Prenatal Screening For Smith-Lemli-Opitz SyndromeCompletedNCT00070850Phase 2
15Simvastatin Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00064792Phase 2
16The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control GroupUnknown statusNCT01762007
17Hemostasis During Hypospadias SurgeryUnknown statusNCT02268019
18Boston Children's Hospital Post Anesthesia Care Unit Outcomes StudyUnknown statusNCT02189642
19SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol SupplementationUnknown statusNCT01434745
20Sterol and Isoprenoid Disease Research Consortium: Smith-Lemli-Opitz SyndromeUnknown statusNCT01356420
21Influence of Pesticide Exposure on the Occurrence of Hypospadias in Newborns in PicardieCompletedNCT02805491
22Long Term Outcome of Hypospadias RepairCompletedNCT02103712
23The Effect of Caudal Block on the Postoperative Complications in Pediatric Patients After Hypospadias RepairCompletedNCT02164682
24The Effect of Anesthetics on Oxidative Stress and Apoptosis Status in ChildrenCompletedNCT02711280
25Visual Guidelines and Tutoring in Pediatric Urological SurgeryCompletedNCT02040389
26The Caudal Space in Children: Ultrasound EvaluationCompletedNCT01896076
27Child's Adipose Cells: Capacity of Tissue RegenerationCompletedNCT02779205
28Estimation of the Carrier Frequency and Incidence of Smith-Lemli-Opitz Syndrome in African AmericansCompletedNCT00017732
29Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias RepairRecruitingNCT02162810
30Effect of Caudal and Penile Block on Hypospadias Repair ComplicationsRecruitingNCT02851290
31Prophylactic Antibiotics or Placebo After Hypospadias RepairRecruitingNCT02096159
32Caudal vs Local Anesthesia in HypospadiasRecruitingNCT02512887
33Antibiotic Use Following Distal and Mid-shaft Hypospadias RepairRecruitingNCT02593903
34DPNB vs. Modified DPNB With Ventromedial Infiltration (DPNB According to Dalens' Technique)RecruitingNCT01974011
35Pregnancy Environment and Newborn MalformationsRecruitingNCT01613638
36Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)RecruitingNCT01773278
37Study of Smith-Lemli-Opitz SyndromeRecruitingNCT00001721
38Decision Support for Parents Receiving Information About Child's Rare DiseaseActive, not recruitingNCT01875640
39Hypospadias and Exome: Identification of New Genes for Familial HypospadiasEnrolling by invitationNCT02495090
40Foreskin Graft Tubularized Incised Plate Urethroplasty vs Tubularized Incised Plate for Primary Hypospadias (FGTIP-TIP)Not yet recruitingNCT02497963
41Does Caudal Block Increase the Incidence of Urethrocutaneous Fistula Formation Following Hypospadias Repair in Infants?Not yet recruitingNCT02861950
42Intelligence Changes Following Minor SurgeryWithdrawnNCT01483313
43A Long-Term Study of Cholesterol Supplements for Smith-Lemli-Opitz SyndromeWithdrawnNCT01413425

Search NIH Clinical Center for Hypospadias


Cochrane evidence based reviews: hypospadias

Genetic Tests for Hypospadias

About this section

Genetic tests related to Hypospadias:

id Genetic test Affiliating Genes
1 Hypospadias26

Anatomical Context for Hypospadias

About this section

MalaCards organs/tissues related to Hypospadias:

35
Skin, Testis, Pituitary, Placenta, Testes, Hypothalamus, Prostate

Animal Models for Hypospadias or affiliated genes

About this section

MGI Mouse Phenotypes related to Hypospadias:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.7AR, FGF10, FGF8, FGFR2, HOXD13, MID1
2MP:00053679.6AR, FGF10, FGF8, FGFR2, HOXA13, HOXD13
3MP:00053719.6AR, CYP17A1, FGF10, FGF8, FGFR2, HOXA13
4MP:00053809.1AR, FGF10, FGF8, FGFR2, HOXA13, HOXD13
5MP:00053788.9AR, ATF3, FGF10, FGF8, FGFR2, HOXA13
6MP:00053798.7AR, ATF3, FGF10, FGF8, FGFR2, HOXA13
7MP:00107688.4AR, CYP17A1, FGF10, FGF8, FGFR2, HOXA13
8MP:00053898.3AR, CYP17A1, FGF10, FGF8, FGFR2, HOXA13
9MP:00053908.3AR, ATF3, CYP17A1, FGF10, FGF8, FGFR2

Publications for Hypospadias

About this section

Articles related to Hypospadias:

(show top 50)    (show all 836)
idTitleAuthorsYear
1
Late surgical correction of hypospadias increases the risk of complications: a 501 consecutive patients series. (28083998)
2017
2
High GMS score hypospadias: Outcomes after one- and two-stage operations. (28063780)
2016
3
Joint effects of genetic variants and residential proximity to pesticide applications on hypospadias risk. (27098078)
2016
4
Response to letter to the editor re 'Worldwide prevalence of hypospadias'. (27641941)
2016
5
Primary hypospadias repair techniques: A review of the evidence. (28057982)
2016
6
Response to commentary to 'Results of distal hypospadias repair after pediatric urology fellowship training: A comparison of junior surgeons to their mentor'. (27160978)
2016
7
Psychosocial outcome in adult men born with hypospadias. (28087231)
2016
8
Tetraploid/Diploid Mosaicism in Cultured Genital Skin Fibroblasts: Is It Causally Related to Penoscrotal Hypospadias? (27587991)
2016
9
Maternal Exposure to Domestic Hair Cosmetics and Occupational Endocrine Disruptors Is Associated with a Higher Risk of Hypospadias in the Offspring. (28036072)
2016
10
Re: Two-Stage Repair for Severe Proximal Hypospadias Using Oral Mucosal Grafts: Combination of a Modified Bracka Method and a Modified Byars Flap Method. (27597106)
2016
11
Genetic polymorphisms in ESR1 and ESR2 genes, and risk of hypospadias in a multiethnic study population. (25463985)
2015
12
Outcome analysis of tubularized incised plate repair in hypospadias: is a catheter necessary? (23548842)
2013
13
Objective use of testosterone reveals androgen insensitivity in patients with proximal hypospadias. (23962431)
2013
14
Two-stage complex hypospadias repair when urethral plate has to be divided: ventral corporoplasty using a tunica vaginalis flap. (23764375)
2013
15
Hormone therapy in hypospadias surgery: a systematic review. (23602841)
2013
16
Urethral plate grafting improves the results of tubularized incised plate urethroplasty in primary hypospadias. (24360521)
2013
17
Re: split dorsal dartos flap transposed ventrally as a bed for preputial skin graft in primary staged hypospadias repair. (23561384)
2013
18
Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias. (23036983)
2013
19
Penile length is comparable in boys with and without hypospadias. (22030456)
2012
20
Association of variants in genes involved in environmental chemical metabolism and risk of cryptorchidism and hypospadias. (22648180)
2012
21
Modified Snodgrass tubularized incised plate urethroplasty prevents fistula formation in hypospadias. (22868631)
2012
22
Re: Tubularized incised plate proximal hypospadias repair: continued evolution and extended applications. (21306956)
2011
23
Hypospadias: interactions between environment and genetics. (21256920)
2011
24
Online hypospadias support group data analysis. (21376203)
2011
25
Tubularized incised plate proximal hypospadias repair: Continued evolution and extended applications. (20598641)
2011
26
Hypospadias repair with tubularized incised plate: Does the obstructive flow pattern resolve spontaneously? (20630805)
2011
27
Analysis of risk factors for glans dehiscence after tubularized incised plate hypospadias repair. (21420110)
2011
28
Hypospadias associated with hypertelorism, the mildest phenotype of Opitz syndrome. (21326312)
2011
29
Relationship between maternal dietary patterns and hypospadias. (21470265)
2011
30
Urinary flow patterns in infants with distal hypospadias. (20598640)
2011
31
Hypospadias algorithm: The way to propose. (20924445)
2010
32
Is there a need to do routine sonological, urodynamic study and cystourethroscopic evaluation of patients with simple hypospadias? (20625749)
2010
33
What is new in cryptorchidism and hypospadias--a critical review on the testicular dysgenesis hypothesis. (20920735)
2010
34
Repair of extensive perineal hypospadias in a Boston terrier using tubularized incised plate urethroplasty. (19949553)
2009
35
Midterm outcome of the modified Bretteville technique for hypospadias reconstruction. (19158007)
2009
36
Is tubularization of the mobilized urethral plate a better alternative to tubularization of an incised urethral plate for hypospadias repair? (19096854)
2009
37
Patient with bilateral breast enlargement and hypospadias. (19182761)
2009
38
Repair of distal hypospadias and preputioplasty in one operation. Risks and advantages. (19322007)
2009
39
Use of the processus vaginalis: A new technique for reinforcing the neourethra in hypospadias associated with undescended testis. (19672367)
2009
40
Hypospadias in a male patient with 21-hydroxylase deficiency. (18719294)
2008
41
Maternal and paternal risk factors for cryptorchidism and hypospadias: a case-control study in newborn boys. (15531444)
2004
42
Identification of mutations of SRD5A2 gene and SRY gene in patients with hypospadias]. (10514539)
1999
43
Androgen receptor gene mutations are rarely associated with isolated penile hypospadias. (8683794)
1996
44
Testicular cancer in association with developmental renal anomalies and hypospadias. (8560668)
1996
45
Macrocephaly, hypospadias grade III-IV, and fragile X-like behavior in identical twins without involvement of the FMR-1 gene. (8897045)
1996
46
Two-stage repair for severe hypospadias. (8015102)
1994
47
Single-stage correction of posterior hypospadias (178 cases). Comparison of three techniques: free skin graft, free bladder mucosal graft, transverse pedicle preputial graft. (1747361)
1991
48
Gonadotropins and gonadal function in transsexualism and hypospadias. (3099183)
1986
49
An autosomal dominant syndrome of radial hypoplasia, triphalangeal thumbs, hypospadias, and maxillary diastema. (7137222)
1982
50
Female hypospadias associated with unilateral renal agenesis and genital malformations. A case report. (5566106)
1971

Variations for Hypospadias

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Copy number variations for Hypospadias from CNVD:

6 (show all 17)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
11282096154402135154609693DeletionMORHypospadia
2128211194030000043000000DeletionWilmsHypospadia
3128213194030000043000000DeletiongeneHypospadia
4128215194030000043000000DeletioninteractingHypospadia
5128217194030000043000000DeletionproteinHypospadia
6128219194030000043000000DeletionproximalHypospadia
7128221194030000043000000DeletiontheHypospadia
812822347061889270712488DeletiontoHypospadia
9128225194030000043000000DeletiontumorHypospadia
101371352138750000144750000DeletionARHGAP15Hypospadia
111371392138750000144750000DeletionGTDC1Hypospadia
121371432138750000144750000DeletionHNMTHypospadia
131371472138750000144750000DeletionKYNUHypospadia
141371512138750000144750000DeletionLOC64702Hypospadia
151371552138750000144750000DeletionLRP1BHypospadia
161371592138750000144750000DeletionNXPH2Hypospadia
171371632138750000144750000DeletionSPOPLHypospadia

Expression for genes affiliated with Hypospadias

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Search GEO for disease gene expression data for Hypospadias.

Pathways for genes affiliated with Hypospadias

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GO Terms for genes affiliated with Hypospadias

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Cellular components related to Hypospadias according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell body fiberGO:00708529.9SRD5A1, SRD5A2

Biological processes related to Hypospadias according to GeneCards Suite gene sharing:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1morphogenesis of an epithelial foldGO:006057110.8AR, HOXD13
2male genitalia morphogenesisGO:004880810.8AR, FGF10
3animal organ formationGO:004864510.7AR, FGF10
4phthalate metabolic processGO:001896310.7CYP17A1, SRD5A2
5negative regulation of female gonad developmentGO:200019510.7NR5A1, WT1
6mammary gland bud formationGO:006061510.7FGF10, FGFR2
7mesenchymal cell differentiation involved in lung developmentGO:006091510.7FGF10, FGFR2
8branch elongation involved in salivary gland morphogenesisGO:006066710.7FGF10, FGFR2
9fibroblast growth factor receptor signaling pathway involved in mammary gland specificationGO:006059510.7FGF10, FGFR2
10prostate epithelial cord arborization involved in prostate glandular acinus morphogenesisGO:006052710.6FGFR2, HOXD13
11cellular response to gonadotropin stimulusGO:007137110.6CYP17A1, WT1
12lacrimal gland developmentGO:003280810.6FGF10, FGFR2
13response to follicle-stimulating hormoneGO:003235410.6SRD5A1, SRD5A2
14gonad developmentGO:000840610.6FGF8, WT1
15organ inductionGO:000175910.6FGF10, FGF8
16epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.6FGF10, FGFR2
17gland morphogenesisGO:002261210.6FGFR2, HOXD13
18embryonic hindgut morphogenesisGO:004861910.6HOXA13, HOXD13
19regulation of branching involved in prostate gland morphogenesisGO:006068710.6FGFR2, HOXD13
20biphenyl metabolic processGO:001887910.6CYP17A1, SRD5A2
21bud elongation involved in lung branchingGO:006044910.5FGF10, FGFR2
22epidermis morphogenesisGO:004873010.5FGF10, FGFR2
23dibenzo-p-dioxin metabolic processGO:001889410.5CYP17A1, SRD5A2
24limb bud formationGO:006017410.5FGF10, FGFR2
25sex determinationGO:000753010.5SRD5A1, WT1
26female genitalia developmentGO:003054010.4SRD5A1, SRD5A2
27reproductive structure developmentGO:004860810.4AR, FGFR2
28phosphatidylinositol-3-phosphate biosynthetic processGO:003609210.3FGF10, FGF8, FGFR2
29limb morphogenesisGO:003510810.3FGF10, FGF8, HOXD13
30progesterone metabolic processGO:004244810.3CYP17A1, SRD5A1
31regulation of phosphatidylinositol 3-kinase signalingGO:001406610.3FGF10, FGF8, FGFR2
32otic vesicle formationGO:003091610.3FGF10, FGF8, FGFR2
33organ growthGO:003526510.2FGF10, FGFR2
34protein localization to microtubuleGO:003537210.2MID1, MID2
35positive regulation of male gonad developmentGO:200002010.2NR5A1, SRY, WT1
36branching involved in salivary gland morphogenesisGO:006044510.2FGF10, FGF8, FGFR2
37adrenal gland developmentGO:003032510.1CYP17A1, NR5A1, WT1
38positive regulation of Wnt signaling pathwayGO:003017710.1FGF10, FGFR2, ZEB2
39steroid biosynthetic processGO:000669410.1CYP17A1, SRD5A1, SRD5A2
40inner ear morphogenesisGO:004247210.0FGF10, FGF8, FGFR2
41androgen biosynthetic processGO:000670210.0CYP17A1, HSD17B3, SRD5A1, SRD5A2
42bone developmentGO:006034810.0FGF8, FGFR2, SRD5A1, SRD5A2
43response to organic cyclic compoundGO:00140709.9FGF10, FGF8, SRD5A1, SRD5A2
44cell-cell signalingGO:00072679.7AR, FGF10, FGFR2, NR5A1, SRD5A2
45epithelial cell differentiationGO:00308559.6FGF10, FGFR2, WT1
46male genitalia developmentGO:00305399.5FGF8, HOXD13, HSD17B3, SRD5A1, SRD5A2, WT1
47hippocampus developmentGO:00217669.4CYP17A1, SRD5A1, SRD5A2, ZEB2
48male gonad developmentGO:00085849.3AR, MAMLD1, NR5A1, SRD5A1, SRD5A2, SRY
49cell differentiationGO:00301549.3FGF10, NR5A1, SRD5A1, SRD5A2, SRY
50positive regulation of transcription from RNA polymerase II promoterGO:00459448.6AR, ATF3, FGF10, FGFR2, HOXD13, NR5A1

Molecular functions related to Hypospadias according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1cholestenone 5-alpha-reductase activityGO:004775110.7SRD5A1, SRD5A2
23-oxo-5-alpha-steroid 4-dehydrogenase activityGO:000386510.7SRD5A1, SRD5A2
3amide bindingGO:003321810.6SRD5A1, SRD5A2
41-phosphatidylinositol-3-kinase activityGO:001630310.3FGF10, FGF8, FGFR2
5phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:004693410.2FGF10, FGF8, FGFR2
6Ras guanyl-nucleotide exchange factor activityGO:00050889.8FGF10, FGF8, FGFR2
7sequence-specific DNA bindingGO:00435659.3AR, HOXA13, HOXA4, NR5A1, WT1
8transcription factor activity, sequence-specific DNA bindingGO:00037008.8AR, ATF3, HOXA4, HOXD13, NR5A1, WT1

Sources for Hypospadias

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet