MCID: HYP048
MIFTS: 25

Hypotropia malady

Neuronal diseases, Eye diseases categories

Summaries for Hypotropia

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Hypertropia is a condition of misalignment of the eyes (strabismus), whereby the visual axis of one eye... more...

MalaCards: Hypotropia is related to esotropia and hypertropia. An important gene associated with Hypotropia is PHOX2A (paired-like homeobox 2a). Affiliated tissues include eye, testes and thyroid, and related mouse phenotypes are no phenotypic analysis and growth/size/body.

Aliases & Classifications for Hypotropia

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 41NCIt, 28ICD9CM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Eye diseases


Aliases & Descriptions:

hypotropia 9 11 63


External Ids:

Disease Ontology9 DOID:9841
NCIt41 C42086
SNOMED-CT59 29491004
ICD9CM28 378.32

Related Diseases for Hypotropia

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Hypotropia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1esotropia10.2
2hypertropia10.0
3exotropia10.0
4eye disease10.0
5myopia10.0
6strabismus10.0
7thyroiditis10.0

Graphical network of diseases related to Hypotropia:



Diseases related to hypotropia

Symptoms for Hypotropia

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Drugs & Therapeutics for Hypotropia

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Hypotropia

Search CenterWatch for Hypotropia

Genetic Tests for Hypotropia

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Anatomical Context for Hypotropia

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Sources:
34MalaCards
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MalaCards organs/tissues related to Hypotropia:

34
Eye, Testes, Thyroid

Animal Models for Hypotropia or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Hypotropia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.1PHOX2A, MC1R
2MP:00053789.1PHOX2A, MC1R
3MP:00053869.0PHOX2A, MC1R
4MP:00053848.8PHOX2A, MC1R

Publications for Hypotropia

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53PubMed
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Articles related to Hypotropia:

(show all 19)
idTitleAuthorsYear
1
Surgical management of hypotropia in congenital fibrosis of extraocular muscles (CFEOM) presented by pseudoptosis. (23277737)
2013
2
Managing a case of hypotropia with a positive traction test. (23343087)
2013
3
Diagnosis and surgical treatment of unilateral restrictive hypotropia and esotropia. (21397798)
2011
4
The role of thyroid eye disease and other factors in the overcorrection of hypotropia following unilateral adjustable suture recession of the inferior rectus (an American Ophthalmological Society thesis). (22253487)
2011
5
Acquired cyclic exotropia and hypotropia. (19541276)
2009
6
Dissociated hypotropia: clinical features and surgical management of two cases. (17070470)
2006
7
Fixation linked hypotropia in high myopia. A report of two similar cases. (12597767)
2003
8
Spontaneous recovery from inferior rectus contracture (consecutive hypotropia) following local anesthetic injury. (12765542)
2003
9
A rare case of bilateral dissociated hypotropia and unilateral dissociated esotropia. (11304822)
2001
10
Abduction paralysis with hypotropia: sign of weakness of a contralateral superior oblique. (11840359)
2001
11
Disintegration of the inferior rectus muscle during strabismus surgery for restrictive hypotropia. (10928671)
2000
12
Bilateral inferior rectus muscle recession for correction of hypotropia in dysthyroid ophthalmopathy. (10428589)
1999
13
Postanesthetic hypotropia. (9610432)
1998
14
Postanesthetic hypotropia: a unique syndrome in left eyes. (9423914)
1997
15
Hypercorrection of hypotropia in Graves ophthalmopathy. (8433813)
1993
16
Late overcorrection of hypotropia in Graves ophthalmopathy. Predictive factors. (1565447)
1992
17
Management of ipsilateral ptosis with hypotropia. (3096370)
1986
18
Primary-position hypotropia after anterior transposition of the inferior oblique. (3947298)
1986
19
Infantile contracture of inferior rectus muscle with resultant mechanical hypotropia. (5362882)
1969

Variations for Hypotropia

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Expression for genes affiliated with Hypotropia

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hypotropia

Search GEO for disease gene expression data for Hypotropia.

Pathways for genes affiliated with Hypotropia

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Compounds for genes affiliated with Hypotropia

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GO Terms for genes affiliated with Hypotropia

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Sources:
17Gene Ontology
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Biological processes related to Hypotropia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription from RNA polymerase II promoterGO:0459449.1PHOX2A, MC1R

Products for genes affiliated with Hypotropia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hypotropia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet