IHCM
MCID: ICH013
MIFTS: 16

Ichthyosis Hystrix, Curth Macklin Type (IHCM) malady

Summaries for Ichthyosis Hystrix, Curth Macklin Type

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MalaCards: Ichthyosis Hystrix, Curth Macklin Type, also known as curth-macklin type ichthyosis hystrix, is related to ichthyosis histrix, curth-macklin type and epidermolysis bullosa. An important gene associated with Ichthyosis Hystrix, Curth Macklin Type is KRT1 (keratin 1), and among its related pathways is Cytoskeleton remodeling Keratin filaments. The compounds asparagine and valine have been mentioned in the context of this disorder.

Aliases & Classifications for Ichthyosis Hystrix, Curth Macklin Type

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42NIH Rare Diseases, 60UMLS
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Aliases & Descriptions:

ichthyosis hystrix, curth macklin type 42 60
curth-macklin type ichthyosis hystrix 42
ihcm 42


Related Diseases for Ichthyosis Hystrix, Curth Macklin Type

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Ichthyosis Hystrix, Curth Macklin Type:



Diseases related to ichthyosis hystrix, curth macklin type

Clinical Features for Ichthyosis Hystrix, Curth Macklin Type

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Drugs & Therapeutics for Ichthyosis Hystrix, Curth Macklin Type

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Ichthyosis Hystrix, Curth Macklin Type

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Anatomical Context for Ichthyosis Hystrix, Curth Macklin Type

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Animal Models for Ichthyosis Hystrix, Curth Macklin Type or affiliated genes

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Publications for Ichthyosis Hystrix, Curth Macklin Type

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Genetic Variations for Ichthyosis Hystrix, Curth Macklin Type

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Expression for genes affiliated with Ichthyosis Hystrix, Curth Macklin Type

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Ichthyosis Hystrix, Curth Macklin Type

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Pathways for genes affiliated with Ichthyosis Hystrix, Curth Macklin Type

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12EMD Millipore
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Pathways related to Ichthyosis Hystrix, Curth Macklin Type according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1KRT1, KRT5

Compounds for genes affiliated with Ichthyosis Hystrix, Curth Macklin Type

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44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Ichthyosis Hystrix, Curth Macklin Type according to GeneCards/GeneDecks:

(show all 14)
idCompoundScoreTop Affiliating Genes
1asparagine449.4KRT1, KRT5
2valine449.4KRT1, KRT5
3phenylalanine449.4KRT1, KRT5
4retinoid449.4KRT5, KRT1
512-o-tetradecanoylphorbol 13-acetate449.4KRT1, KRT5
6paraffin449.3KRT1, KRT5
7proline449.3KRT1, KRT5
8lysine449.3KRT5, KRT1
9aspartate449.2KRT1, KRT5
10leucine449.2KRT1, KRT5
11progesterone44 59 28 11 2413.1KRT5, KRT1
12threonine449.1KRT1, KRT5
13testosterone44 59 11 2412.0KRT1, KRT5
14arginine448.8KRT1, KRT5

GO Terms for genes affiliated with Ichthyosis Hystrix, Curth Macklin Type

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16Gene Ontology
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Cellular components related to Ichthyosis Hystrix, Curth Macklin Type according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:0450959.1KRT1, KRT5

Products for genes affiliated with Ichthyosis Hystrix, Curth Macklin Type

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Ichthyosis Hystrix, Curth Macklin Type

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet