MCID: ICH054
MIFTS: 37

Ichthyosis, X-Linked malady

Categories: Genetic diseases, Rare diseases, Eye diseases, Skin diseases

Aliases & Classifications for Ichthyosis, X-Linked

About this section
Sources:
49OMIM, 11diseasecard, 22GeneTests, 67UniProtKB/Swiss-Prot, 36MeSH, 65UMLS, 32LifeMap Discovery®, 10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 47Novoseek, 27ICD10, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 34MedGen, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Ichthyosis, X-Linked:

Name: Ichthyosis, X-Linked 49 11 22 67 36 65
X-Linked Ichthyosis 32 10 45 12 51
Placental Steroid Sulfatase Deficiency 45 22 67 65
Steroid Sulfatase Deficiency 45 22 51 67
Steroid Sulfatase Deficiency Disease 45 65
X-Linked Ichthyosis with Steryl-Sulphatase Deficiency 10
X-Linked Placental Steryl-Sulphatase Deficiency 10
Recessive X-Linked Ichthyosis 51
X-Linked Recessive Ichthyosis 10
 
Speech-Sound Disorder 65
X Linked Ichthyosis 45
Ichthyosis X-Linked 47
Ssdd 45
Rxli 51
Xli 51
Ixl 67
Ssd 45

Characteristics:

Orphanet epidemiological data:

51
x-linked ichthyosis:
Inheritance: X-linked recessive; Prevalence: 1-5/10000 (Europe); Age of onset: Neonatal; Age of death: normal life expectancy

HPO:

61
ichthyosis, x-linked:
Inheritance: x-linked recessive inheritance


Classifications:



External Ids:

OMIM49 308100
Disease Ontology10 DOID:1700
ICD1027 Q80.1
MeSH36 D016114
NCIt42 C84779
Orphanet51 461
ICD10 via Orphanet28 Q80.1
MESH via Orphanet37 D016114
UMLS via Orphanet66 C0079588, C2717836
UMLS65 C0079588, C2720163, C1838022 C2717836, more

Summaries for Ichthyosis, X-Linked

About this section
NIH Rare Diseases:45 X-linked ichthyosis is a disorder in which the skin cells are produced at a normal rate but they do not separate properly at the surface of the stratum corneum (the outermost layer of the skin). this slows the rate of shedding of the skin cells, resulting in a build-up of scales. the scales of x-linked ichthyosis are often dark and usually cover only a portion of the body. typically, the trunk and back of the neck are more likely to be affected. scales are usually not found on the face, scalp, palms of the hands, and soles of the feet. x-linked ichthyosis mostly affects males. it is usually caused by a mutation or deletion in the sts gene and is inherited in an x-linked recessive manner. in rare cases, the ichthyosis can be part of a genetic syndrome in which other parts of the body are affected. topical treatment may consist of alpha-hydroxy acids, lubricating bath oils, and emollients. for adult patients, systemic retinoids may be an option, especially during winter when the ichthyosis is often more severe. the ichthyosis is life-long, but the scaling may improve with age. last updated: 3/15/2016

MalaCards based summary: Ichthyosis, X-Linked, also known as x-linked ichthyosis, is related to chondrodysplasia punctata with steroid sulfatase deficiency and syndromic x-linked ichthyosis, and has symptoms including hypohidrosis, hyperkeratosis and dry skin. An important gene associated with Ichthyosis, X-Linked is STS (Steroid Sulfatase (Microsomal), Isozyme S), and among its related pathways are Sphingolipid metabolism and Gamma carboxylation, hypusine formation and arylsulfatase activation. Affiliated tissues include skin, brain and testes.

UniProtKB/Swiss-Prot:67 Ichthyosis, X-linked: A keratinization disorder manifesting with mild erythroderma and generalized exfoliation of the skin within a few weeks after birth. Affected boys later develop large, polygonal, dark brown scales, especially on the neck, extremities, trunk, and buttocks.

OMIM:49 Ichthyosis is a genetically heterogeneous disorder of the skin. See, e.g., autosomal dominant ichthyosis vulgaris... (308100) more...

Wikipedia:68 X-linked ichthyosis (XLI) (also known as \"Steroid sulfatase deficiency,\" and \"X-linked recessive... more...

Related Diseases for Ichthyosis, X-Linked

About this section

Diseases related to Ichthyosis, X-Linked via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
idRelated DiseaseScoreTop Affiliating Genes
1chondrodysplasia punctata with steroid sulfatase deficiency12.6
2syndromic x-linked ichthyosis11.0
3atrial fibrillation10.4
4autosomal dominant chondrodysplasia punctata10.3ARSH, STS
5relapsing polychondritis10.3
6encephalitis10.3
7limbic encephalitis10.3
8ichthyosis, autosomal recessive 4b10.3FLG, TGM1
9brugada syndrome10.3
10short qt syndrome10.3
11azoospermia10.3
12long qt syndrome10.3
13colorectal cancer10.3
14hemochromatosis10.3
15adenoiditis10.3
16melanoma10.3
17salivary gland adenoid cystic carcinoma10.3
18aortitis10.3
19dystonia10.3
20lymphosarcoma10.3
21limb dystonia10.3
22zygomycosis10.3
23mucopolysaccharidosis iv10.3ARSH, SUMF1
24ciliary dyskinesia, primary, 2910.3ARSH, SUMF1
25incontinentia pigmenti10.3ARSH, SUMF1
26diastrophic dysplasia10.2FLG, TGM1
27lung cancer10.2
28epilepsy benign neonatal dominant form10.2FLG, KRT10
29multiple sulfatase deficiency10.1ARSH, STS, SUMF1
30venous hemangioma10.1FLG, KRT10
31skin pilomatrix carcinoma10.1FLG, KRT10
32opitz-gbbb syndrome10.1NLGN4X, STS, VCX3A
33bowenoid papulosis10.1FLG, KRT10
34colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas10.1FLG, KRT10
35cough variant asthma10.1KRT12, STS
36methemoglobinemia, type i10.0ARSH, SUMF1
37skin squamous cell carcinoma10.0FLG, KRT10
38epidermolysis bullosa simplex, koebner type10.0KRT12, STS
39agammaglobulinemia10.0ARSH, STS
40fuchs' endothelial dystrophy10.0KRT12, STS
41corneal dystrophy, epithelial basement membrane10.0KRT12, STS
42benign eccrine breast spiradenoma9.9FLG, KRT10
43palmoplantar keratoderma, epidermolytic9.9FLG, KRT10, TGM1
44ichthyosis, cyclic, with epidermolytic hyperkeratosis9.9FLG, KRT10, TGM1
45small intestine lymphoma9.9FLG, KRT10, TGM1
46cirrhosis, north american indian childhood type9.9KRT12, STS
47otosclerosis 49.9KRT12, STS
48ichthyosis vulgaris9.8FLG, KRT10, STS, TGM1
49endocrine gland cancer9.8FLG, KRT10, STS, TGM1
50fanconi anemia, complementation group b7.5AP1S1, ARSC2, ARSH, FLG, KRT10, KRT12

Graphical network of the top 20 diseases related to Ichthyosis, X-Linked:



Diseases related to ichthyosis, x-linked

Symptoms for Ichthyosis, X-Linked

About this section

Symptoms by clinical synopsis from OMIM:

308100

Clinical features from OMIM:

308100

Symptoms:

 51 (show all 11)
  • hypohidrosis/decreased sweating/thermoregulation disorder/heat intolerance
  • hyperkeratosis/ainhum/hyperkeratotic skin fissures
  • dry/squaly skin/exfoliation
  • ichthyosis/ichthyosiform dermatitis
  • x-linked recessive inheritance
  • insterstitial/subtelomeric microdeletion/deletion
  • corneal clouding/opacity/vascularisation
  • hyperactivity/attention deficit
  • undescended/ectopic testes/cryptorchidia/unfixed testes
  • speech troubles/aphasia/dysphasia/echolalia/mutism/logorrhea/dysprosodia
  • autism/autistic disoders

HPO human phenotypes related to Ichthyosis, X-Linked:

(show all 27)
id Description Frequency HPO Source Accession
1 hypohidrosis hallmark (90%) HP:0000966
2 hyperkeratosis hallmark (90%) HP:0000962
3 dry skin hallmark (90%) HP:0000958
4 ichthyosis hallmark (90%) HP:0008064
5 cognitive impairment typical (50%) HP:0100543
6 opacification of the corneal stroma typical (50%) HP:0007759
7 attention deficit hyperactivity disorder typical (50%) HP:0007018
8 neurological speech impairment typical (50%) HP:0002167
9 testicular neoplasm occasional (7.5%) HP:0010788
10 renal hypoplasia/aplasia occasional (7.5%) HP:0008678
11 abnormality of the sense of smell occasional (7.5%) HP:0004408
12 short stature occasional (7.5%) HP:0004322
13 abnormality of the abdominal wall occasional (7.5%) HP:0004298
14 abnormality of the stomach occasional (7.5%) HP:0002577
15 acute leukemia occasional (7.5%) HP:0002488
16 abnormality of neuronal migration occasional (7.5%) HP:0002269
17 seizures occasional (7.5%) HP:0001250
18 autism occasional (7.5%) HP:0000717
19 renal insufficiency occasional (7.5%) HP:0000083
20 cryptorchidism occasional (7.5%) HP:0000028
21 neurological speech impairment occasional (7.5%) HP:0002167
22 ichthyosis HP:0008064
23 opacification of the corneal stroma HP:0007759
24 congenital ichthyosiform erythroderma HP:0007431
25 neoplasm HP:0002664
26 abnormality of metabolism/homeostasis HP:0001939
27 cryptorchidism HP:0000028

Drugs & Therapeutics for Ichthyosis, X-Linked

About this section

Drugs for Ichthyosis, X-Linked (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 190)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Pregabalinapproved, illicit, investigationalPhase 4, Phase 3340148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
2
LorazepamapprovedPhase 4112846-49-13958
Synonyms:
(+-)-7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
(+/-)-Lorazepam
(±)-Lorazepam
5-25-02-00248 (Beilstein Handbook Reference)
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one
7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
846-49-1
AC1L1H3H
AHP Brand of Lorazepam
Almazine
Alzapam
Anxiedin
Anxira
Anzepam
Aplacasse
Aplacassee
Apo Lorazepam
Apo-Lorazepam
ApoLorazepam
Apotex Brand of Lorazepam
Aripax
Ativan
Ativan (TN)
Azurogen
BRN 0759084
Baxter Brand of Lorazepam
Bonatranquan
Bonton
CHEBI:116959
CHEMBL580
CID3958
CPD000058410
D00365
D008140
DB00186
DEA No. 2885
Delormetazepam
Demethyllormetazepam
Desitin Brand of Lorazepam
DivK1c_000965
Dolorgiet Brand of Lorazepam
Donix
Duralozam
Durazolam
EINECS 212-687-6
Efasedan
Emotion
Emotival
Equitam
HMS2052H07
HMS503A11
IDI1_000965
Idalprem
KBio1_000965
Kalmalin
L-Lorazepam Acetate
L1764_SIGMA
LS-34141
Larpose
Laubeel
Llorens Brand of Lorazepam
Lomesta
Lopam
Lorabenz
Lorafen
Loram
Lorans
Lorapam
Lorat
Lorax
Loraz
Lorazene
Lorazep
Lorazepam
Lorazepam (JP15/USP/INN)
Lorazepam AHP Brand
Lorazepam Apotex Brand
Lorazepam Baxter Brand
Lorazepam Desitin Brand
Lorazepam Dolorgiet Brand
Lorazepam Fabra
Lorazepam Genericon
Lorazepam Intensol
Lorazepam Lannacher
Lorazepam Llorens Brand
Lorazepam Medical
Lorazepam Medical Brand
Lorazepam Medix Brand
Lorazepam Novartis Brand
Lorazepam Novopharm Brand
Lorazepam Nu-Pharm Brand
Lorazepam Riemser Brand
Lorazepam Wyeth Brand
Lorazepam [USAN:INN:BAN:JAN]
 
Lorazepam ct-Arzneimittel Brand
Lorazepam neuraxpharm
Lorazepam neuraxpharm Brand
Lorazepam preservative free
Lorazepam ratiopharm
Lorazepam ratiopharm Brand
Lorazepam-Efeka
Lorazepam-neuraxpharm
Lorazepam-ratiopharm
Lorazepamum
Lorazepamum [INN-Latin]
Lorazepan Chobet
Lorazepan Richet
Lorazin
Lorazon
Lorenin
Loridem
Lorivan
Lormetazepam
Lorsedal
Lorsilan
Lorzem
Lozepam
Max Pax
Medical Brand of Lorazepam
Medical, Lorazepam
Medix Brand of Lorazepam
Merck dura Brand of Lorazepam
Merlit
Methyllorazepam
MolPort-002-051-769
N-Methyllorazepam
NCGC00159439-02
NINDS_000965
NSC 289758
NSC289758
Nervistop L
Nervistopl
Norlormetazepam
Novartis Brand of Lorazepam
Novhepar
Novo Lorazem
Novo-Lorazem
Novolorazem
Novopharm Brand of Lorazepam
Nu Loraz
Nu Pharm Brand of Lorazepam
Nu-Loraz
Nu-Pharm Brand of Lorazepam
NuLoraz
O-Chlorooxazepam
O-Chloroxazepam
Orfidal
Orfidal Wyeth
Pro Dorm
Pro dorm
Psicopax
Punktyl
Quait
Renaquil
Riemser Brand of Lorazepam
Rocosgen
SAM001246833
Securit
Sedatival
Sedazin
Sedicepan
Sedizepan
Serra Pamies Brand of Lorazepam
Sidenar
Silence
Sinestron
Somagerol
Stapam
Tavor
Temesta
Tolid
Tranqipam
Trapax
UNII-O26FZP769L
Upan
Vigiten
WLN: T67 GMV JN IHJ CG IQ KR BG
WY4036
Wy 4036
Wy-4036
Wyeth Brand of Lorazepam
Wyeth, Orfidal
Wypax
ct Arzneimittel Brand of Lorazepam
ct-Arzneimittel Brand of Lorazepam
lorazep von ct
lorazepam
lorazepam (Ativan)
nchembio747-comp26
neuraxpharm Brand of Lorazepam
o-Chlorooxazepam
o-Chloroxazepam
ratiopharm Brand of Lorazepam
3
Sodium Tetradecyl SulfateapprovedPhase 451191-50-014492, 5248
Synonyms:
1-Tetradecanol, 1-(hydrogen sulfate), sodium salt (1:1)
1-Tetradecanol, hydrogen sulfate, sodium salt
1191-50-0
22088-37-5
C14H28O5S
CHEMBL541505
CID14492
EINECS 214-737-2
LS-148911
Monotetradecylsulfate sodium salt
Monotetradecylsulphate sodium salt
Myristyl sulfate, sodium salt
NSC 139032
Natri tetradecylsulfas
Natrii tetradecyclis sulfas
Natrii tetradecyclis sulfas [INN-Latin]
Niaproof 4
S.T.D
S.T.D.
STDS
 
STS
Sodium myristyl sulfate
Sodium myristyl sulphate
Sodium tetradecyl sulphate
Sodium tetradecylsulfate
Sotradecol
Sotradecol Sodium
Sulfuric acid, monotetradecyl ester, sodium salt
Sulfuric acid, myristyl ester, sodium salt
Tesapon K 14
Tetradecilsulfato sodico [INN-Spanish]
Tetradecyl hydrogen sulfate
Tetradecyl hydrogen sulphate
Tetradecyl sodium sulfate
Tetradecyl sodium sulphate
Tetradecyl sulfate
Tetradecyl sulfate de sodium [INN-French]
Tetradecyl sulfate, sodium salt
Tetradecyl sulfuric Acid
Tetradecyl sulphate
Texapon K 14
Trombavar
4
Selegilineapproved, investigationalPhase 4, Phase 3, Phase 22614611-51-926757, 5195
Synonyms:
(-)-(N)-Methyl-N-((1R)-1-methyl-2-phenylethyl)prop-2-yn-1-amine
(-)-Deprenil
(2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine
(R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine
(R)-(-)-N-Methyl-N-(1-phenyl-2-propyl)-2-propinylamin
(−)-selegiline
14611-51-9
14611-52-0 (hydrochloride)
2079-54-1 (deprenyl.hydrochloride)
AC1L1BTZ
AC1Q2860
AKOS000281115
Anipryl
Apo-Selegiline
BPBio1_000687
BRD-K86434416-001-02-7
BRD-K86434416-003-03-1
BSPBio_000623
BSPBio_001589
C07245
C13H17N
CHEBI:9086
CHEMBL972
CID26757
Carbex
D03731
DB01037
Deprenyl
Eldepryl
Emsam
Emsam (TN)
Gen-Selegiline
HMS1791P11
HMS1989P11
HMS2089D09
Humex
Jumex
 
L-Deprenalin
L-Deprenyl
LS-30156
MolPort-000-883-771
N-methyl-N-[(1R)-1-methyl-2-phenylethyl]prop-2-yn-1-amine
N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine
NCGC00024994-01
NCGC00024994-02
NCGC00024994-03
NCGC00024994-04
Novo-Selegiline
Nu-Selegiline
Prestwick0_000552
Prestwick1_000552
Prestwick2_000552
Prestwick3_000552
SPBio_002544
STK640578
Sd Deprenyl
Selegeline Hcl
Selegeline Hydrochloride
Selegilina
Selegilina [INN-Spanish]
Selegiline (USAN/INN)
Selegiline Hydrochloride
Selegiline Transdermal System (STS) patch
Selegiline [INN:BAN]
Selegiline, (R)-Isomer
Selegilinum
Selegilinum [INN-Latin]
Selegyline
Tocris-1095
UNII-2K1V7GP655
Yumex
ZINC19632633
Zelapar
l-E 250
selegiline
5
PaclitaxelapprovedPhase 4262133069-62-436314
Synonyms:
(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester
12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
157069-30-2
33069-62-4
5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.
7-Epi-Paclitaxel
7-Epi-Taxol
7-Epipaclitaxel
7-Epitaxol
7-epi-Paclitaxel
7-epi-Taxol
AB00513812
ABI 007
ABI-007
ABI007
AC-675
AC1L1IOG
AC1L1VJI
AC1L9AVF
ACon1_002231
ANX-513
Abraxane
Abraxane (TN)
Abraxane I.V. Suspension
Abraxis BioScience brand of albumin-bound paclitaxel
Ambotz33069-62-4
Anzatax
Asotax
BIDD:PXR0046
BMS 181339-01
BMS-181339
BMS-181339-01
BPBio1_000320
BRD-A23723433-001-01-2
BRD-A28746609-001-04-0
BRD-K62008436-001-03-1
BSPBio_000290
BSPBio_001152
BSPBio_002614
Bio-0076
Bio1_000362
Bio1_000851
Bio1_001340
Bio2_000416
Bio2_000896
Bristaxol
C07394
C466458
C47H51NO14
CCRIS 8143
CHEBI:103439
CHEBI:45863
CHEMBL100910
CHEMBL418410
CHEMBL48
CID36314
CID441276
CID4666
CID6713921
CID6915727
CPD-8718
Capxol
D00491
DB01229
DHP-107
DHP-208
DRG-0190
DTS-301
DivK1c_000441
EU-0101201
Ebetaxel
EmPAC
Epitaxol
Genaxol
Genetaxyl
Genexol
Genexol-PM
HMS1362J13
HMS1568O12
HMS1792J13
HMS1922K08
HMS1990J13
HMS2090D07
HMS2093K15
HMS501G03
HSDB 6839
I06-0014
IDI1_000441
IDI1_002171
Intaxel
KBio1_000441
KBio2_000492
KBio2_002016
KBio2_002509
KBio2_003060
KBio2_004584
KBio2_005077
KBio2_005628
KBio2_007152
KBio2_007645
KBio3_000903
KBio3_000904
KBio3_001834
KBio3_002987
KBioGR_000492
KBioGR_001893
 
KBioGR_002509
KBioSS_000492
KBioSS_002016
KBioSS_002517
LMPR0104390001
LS-31070
LipoPac
Lopac0_001201
MBT 0206
MEGxp0_001940
MLS000863266
MLS001077297
MLS002154218
MLS002172439
MLS002695976
MPI-5018
Micellar Paclitaxel
Mitotax
MolPort-001-742-627
MolPort-003-665-783
MolPort-003-932-365
NCGC00024995-02
NCGC00024995-03
NCGC00024995-04
NCGC00024995-05
NCGC00024995-06
NCGC00024995-07
NCGC00164367-01
NCGC00164367-02
NCGC00164367-03
NCI60_000601
NINDS_000441
NK 105
NP-010981
NSC 125973
NSC-125973
NSC125973
NSC358882
Nanotaxel
Neuro_000060
Nova-12005
OAS-PAC-100
OncoGel
Onxal
Onxol
Onxol, Taxol, Nov-Onxol, Paclitaxel
P1632
Paclical
Pacligel
Paclitaxel
Paclitaxel (JAN/USP)
Paclitaxel (JAN/USP/INN)
Paclitaxel (Taxol)
Paclitaxel [USAN:INN:BAN]
Paxceed
Paxene
Paxoral
Plaxicel
Praxel
Prestwick0_000155
Prestwick1_000155
Prestwick2_000155
Prestwick3_000155
Probes2_000350
QW 8184
S-8184 Paclitaxel Injectable Emulsion
S1150_Selleck
SDCCGMLS-0066823.P001
SDP-013
SMP1_000228
SMR000394086
SMR000857385
SPBio_000943
SPBio_002229
SPECTRUM1503908
ST50306996
Spectrum2_000872
Spectrum3_001057
Spectrum4_001197
Spectrum5_001491
Spectrum_001536
T 7402
T1912_SIGMA
T7191_SIGMA
T7402_SIGMA
TA1
TAXOL (TN)
TAXOL, 10-EPI,
TXL
TaxAlbin
Taxol
Taxol A
Taxol Konzentrat
Taxol.RTM. (Registered Trademark)
UNII-P88XT4IS4D
UPCMLD-DP108:001
UPCMLD-DP108:002
Vascular Wrap
Xorane
Yewtaxan
abi-007
albumin-bound paclitaxel
cMAP_000068
nchembio.188-comp1
nchembio.2007.34-comp9
nchembio.215-comp9
nchembio853-comp6
paclitaxel
weekly paclitaxel
6
LidocaineapprovedPhase 41103137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Afterburn
Akten
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bikini Zone Medicated
Bikini Zone Medicated Creme
Bio-0767
Bio-scriptives Lidum
Bio-scriptives Lidum Hemorroidal (anorectal)
Bio-scriptives Lidum Topical Analgesic
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
Burn Relief Leader
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Comfortcaine
Cuivasil
Curacaine Transdermal Corporation
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
Derma Numb
DermaFlex
Desert Harvest Releveum
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Dr. Numb
Dr. Richs Numbing
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gigi Anesthetic Numbing
Gravocain
H-releve Hemorrhoidal
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
Hawaiian Tropic
Hush Anesthetic
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
LS-805
Lanabiotic
 
Laryng-o-jet
Leostesin
Lida-Mantle
Lidall
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine 4% Cream
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Hydrochloride
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocaine hydrochloride
Lidocainum
Lidocainum [INN-Latin]
Lidocare Mist
Lidocaton
Lidocream 4
Lidocream 5
Lidoderm
Lidoderm 5
Lidoject-1
Lidoject-2
Lifestyles Epic Male Genital Desensitizer
Lignocaine
Lignocainum
Lingocaine
Lmx4
Lmx5
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Numb Master Topical Anesthetic
Numb Nuts
Ocean Potion Instant Burn Relief Ice
Octocaine
Octocaine-100
Octocaine-50
Plum Smooth Plumb Numb Gelee
Premjact Male Desensitizer Pound International
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Recticare
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Simplicity Desensitizing
Simply Numb Endure
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Sole Serum
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Walgreens Aloe Vera Pain Relieving
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocaine-mpf
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zcaine Fast Acting Anesthetic
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
7
EpinephrineapprovedPhase 483451-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
8Hypnotics and SedativesPhase 4, Phase 12032
9Gastrointestinal AgentsPhase 4, Phase 3, Phase 26401
10GABA ModulatorsPhase 4, Phase 1657
11Central Nervous System DepressantsPhase 4, Phase 3, Phase 2, Phase 110016
12Neurotransmitter AgentsPhase 4, Phase 2, Phase 114795
13Calcium, DietaryPhase 4, Phase 3, Phase 24678
14Tranquilizing AgentsPhase 4, Phase 3, Phase 2, Phase 13597
15AnestheticsPhase 47385
16Pharmaceutical SolutionsPhase 4, Phase 2, Phase 3, Phase 17004
17Albumin-Bound PaclitaxelPhase 42621
18AntiemeticsPhase 4, Phase 3, Phase 23213
19Psychotropic DrugsPhase 4, Phase 3, Phase 2, Phase 15501
20Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 218510
21calcium channel blockersPhase 4, Phase 31743
22Contraceptives, OralPhase 4, Phase 23734
23Dipeptidyl-Peptidase IV InhibitorsPhase 4779
24Hormone AntagonistsPhase 4, Phase 3, Phase 210002
25Carbon fiberPhase 411
26Tubulin ModulatorsPhase 4, Phase 3, Phase 2, Phase 14279
27Antimitotic AgentsPhase 4, Phase 3, Phase 2, Phase 14296
28Antineoplastic Agents, PhytogenicPhase 4, Phase 2, Phase 3, Phase 14294
29HormonesPhase 4, Phase 3, Phase 211748
30HIV Protease InhibitorsPhase 4, Phase 24558
31Protease InhibitorsPhase 4, Phase 24558
32Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 29988
33Sitagliptin PhosphatePhase 4399
34AnalgesicsPhase 4, Phase 3, Phase 29358
35Anti-Anxiety AgentsPhase 4, Phase 3, Phase 11529
36Hypoglycemic AgentsPhase 44503
37AnticonvulsantsPhase 4, Phase 32249
38IncretinsPhase 41326
39MydriaticsPhase 4525
40Sodium Channel BlockersPhase 41180
41Epinephryl boratePhase 4834
42Vasoconstrictor AgentsPhase 41303
43Respiratory System AgentsPhase 4, Phase 13931
44RacepinephrinePhase 4834
45Anti-Arrhythmia AgentsPhase 42371
46Adrenergic alpha-AgonistsPhase 41300
47Diuretics, Potassium SparingPhase 41445
48Adrenergic AgentsPhase 44204
49Adrenergic beta-AgonistsPhase 41266
50Adrenergic AgonistsPhase 42331

Interventional clinical trials:

(show top 50)    (show all 167)
idNameStatusNCT IDPhase
1A Trial Comparing a Paclitaxel Eluting Stent With Biodegradable Polymer Versus a Bare Metal StentCompletedNCT00825279Phase 4
2Mobility Training Using a Bionic Knee Orthosis in Patients Chronic Post-Stroke: A Case SeriesCompletedNCT01499862Phase 4
3PK Comparison of 6mg and 12mg EMSAM in Elderly vs. Non-ElderlyCompletedNCT00532116Phase 4
4Assessing Glucose Effects of Sitagliptin (Januvia) in Adult Patients With Type 1 DiabetesCompletedNCT00978796Phase 4
5Safety and Efficacy Evaluation Of Pregabalin (Lyrica) With Patients With Generalized Anxiety DisorderCompletedNCT00624780Phase 4
6Frailty and Cognitive Function Assessment of TAVI PatientsRecruitingNCT02650388Phase 4
7Laser Ablation Versus Mechanochemical Ablation TrialRecruitingNCT02627846Phase 4
8AngioSeal Versus Radial Approach in Acute Coronary SyndromeActive, not recruitingNCT01653587Phase 4
9The PARTNER Post Approval Study Part IIActive, not recruitingNCT02184442Phase 4
10Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for SurgeryNot yet recruitingNCT01431222Phase 4
11A Pilot Study Assessing EmSam in Bipolar DepressionTerminatedNCT00535262Phase 4
12RCT Comparing Standard Cannula Delivered FS, UGFS and ClariVein® in the Management of SVIWithdrawnNCT02010437Phase 4
13Star-Close Versus Angio-Seal for Femoral Artery HemostasisWithdrawnNCT00590356Phase 4
14An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic PainCompletedNCT01202227Phase 3
15High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Schizophrenia : a Randomized Controlled StudyCompletedNCT01022489Phase 2, Phase 3
16Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior TherapyCompletedNCT00753688Phase 3
17Study of Palifosfamide-tris in Combination With Doxorubicin in Patients With Front-line Metastatic Soft Tissue SarcomaCompletedNCT01168791Phase 3
18Safety, Tolerability and Efficacy of the Transdermal System in Elderly Subjects With Major DepressionCompletedNCT00285766Phase 3
19Efficacy and Safety Study of Sodium Tanshinone IIA Sulfonate on Pulmonary HypertensionRecruitingNCT01637675Phase 2, Phase 3
20Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant ChemotherapyRecruitingNCT01710176Phase 3
21Study of Anlotinib in Patients With Soft Tissue Sarcoma(STS)(ALTER0203)RecruitingNCT02449343Phase 2, Phase 3
22Role of Barrier Resection in Local Control for Extremity Recurrent Soft Tissue SarcomasRecruitingNCT02120768Phase 3
23Placebo-Controlled Onset-of-Action Study of Flurbiprofen Utilizing the Double-Stopwatch MethodRecruitingNCT01986361Phase 3
24A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue SarcomaRecruitingNCT02451943Phase 3
25Trial Comparing Trabectedin to the Best Supportive Care in Patients With SarcomaRecruitingNCT02672527Phase 3
26NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating and Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk WallRecruitingNCT02379845Phase 2, Phase 3
27A Study For Pregabalin In Patients With FibromyalgiaRecruitingNCT01387607Phase 3
28A Study Of PF-05280586 (Rituximab-Pfizer) Or MabThera® (Rituximab-EU) For The First-Line Treatment Of Patients With CD20-Positive, Low Tumor Burden, Follicular Lymphoma (REFLECTIONS B328-06)RecruitingNCT02213263Phase 3
29Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue SarcomaRecruitingNCT00334854Phase 3
30Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other MalignancyActive, not recruitingNCT00716976Phase 3
31Phase 3 Study to Treat Patients With Soft Tissue SarcomasActive, not recruitingNCT02049905Phase 3
32Preoperative vs Postoperative IMRT for Extremity/Truncal STSNot yet recruitingNCT02565498Phase 3
33A Study to Provide Access to Trabectedin in Participants With Locally Advanced or Metastatic Soft Tissue Sarcoma Who Have Persistent or Recurrent Disease and Who Are Not Expected to Benefit From Currently Available Standard of Care TreatmentNo longer availableNCT00210665Phase 3
34Randomized Double Blind Placebo Controlled Trial of Sodium Thiosulfate (STS) for the Treatment Pain With Calcific Uremic Arteriolopathy a Single Armed Extension Phase Prospectively Observe Lesion Progression in the Presence of STSTerminatedNCT02527213Phase 3
35Near Infrared Spectroscopy (NIRS) in Severe SepsisTerminatedNCT00167596Phase 2, Phase 3
36Pregabalin Trial In HIV Neuropathic PainTerminatedNCT01145417Phase 3
37Pregabalin Versus Placebo In The Treatment Of Neuropathic Pain Associated With HIV NeuropathyTerminatedNCT01049217Phase 3
3812-Week Efficacy And Safety Of Pregabalin In Treating Restless Legs Syndrome (RLS) SubjectsWithdrawnNCT01061372Phase 3
39Neoadjuvant Adriamycin and Ifosfamide Plus High-Dose ICE in Patients With Soft Tissue Sarcoma (STS)CompletedNCT00204646Phase 2
40Radiation Therapy and Intratumoral Autologous Dendritic Cells in Soft Tissue Sarcomas (STS)CompletedNCT01347034Phase 2
41Safety and Effectiveness of the Selegiline "Patch" for Decreased Mental Function in HIV PatientsCompletedNCT00013585Phase 2
42Phase II Trial of Locally Advanced/Metastatic Soft Tissue Sarcoma or Advanced/Metastatic Malignant GISTCompletedNCT00359333Phase 2
43The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).CompletedNCT00385203Phase 2
44Bendamustin Hydrochloride in Patients With Soft Tissue Sarcoma (STS)CompletedNCT00204620Phase 2
45Study on Efficacy and Tolerability of Vorinostat in Patients With Advanced, Metastatic Soft Tissue Sarcoma (STS)CompletedNCT00918489Phase 2
46Selegiline for Smoking Cessation - 1CompletedNCT00439413Phase 2
47Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue SarcomaCompletedNCT00064220Phase 2
48Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue SarcomaCompletedNCT01684449Phase 1, Phase 2
49Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment FailureCompletedNCT01136499Phase 2
50Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder SymptomsCompletedNCT01189812Phase 2

Search NIH Clinical Center for Ichthyosis, X-Linked


Cochrane evidence based reviews: ichthyosis, x-linked

Genetic Tests for Ichthyosis, X-Linked

About this section

Genetic tests related to Ichthyosis, X-Linked:

id Genetic test Affiliating Genes
1 Ichthyosis, X-Linked22 STS

Anatomical Context for Ichthyosis, X-Linked

About this section

MalaCards organs/tissues related to Ichthyosis, X-Linked:

33
Skin, Brain, Testes, Lung, Breast, Bone, Thyroid

Animal Models for Ichthyosis, X-Linked or affiliated genes

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Publications for Ichthyosis, X-Linked

About this section

Variations for Ichthyosis, X-Linked

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UniProtKB/Swiss-Prot genetic disease variations for Ichthyosis, X-Linked:

67
id Symbol AA change Variation ID SNP ID
1STSp.Ser341LeuVAR_007240
2STSp.Trp372ArgVAR_007241
3STSp.Cys446TyrVAR_007242
4STSp.Trp372SerVAR_014020
5STSp.Gly380ArgVAR_014021
6STSp.His444ArgVAR_014022
7STSp.Gln560ProVAR_014023

Clinvar genetic disease variations for Ichthyosis, X-Linked:

5
id Gene Variation Type Significance SNP ID Assembly Location
1STSNM_000351.5(STS): c.1114T> A (p.Trp372Arg)single nucleotide variantPathogenicrs137853165GRCh37Chr X, 7243397: 7243397
2STSNM_000351.5(STS): c.1337G> A (p.Cys446Tyr)single nucleotide variantPathogenicrs137853166GRCh37Chr X, 7252107: 7252107
3STSNM_000351.5(STS): c.1022C> T (p.Ser341Leu)single nucleotide variantPathogenicrs137853167GRCh37Chr X, 7223150: 7223150
4STSNM_000351.5(STS): c.1115G> C (p.Trp372Ser)single nucleotide variantPathogenicrs137853168GRCh37Chr X, 7243398: 7243398
5STSNM_000351.5(STS): c.1331A> G (p.His444Arg)single nucleotide variantPathogenicrs137853169GRCh37Chr X, 7252101: 7252101
6STSSTS, IVS8DS, G-T, +1single nucleotide variantPathogenic
7NC_000023.11deletionPathogenicGRCh38Chr X, 6499768: 8193324
8NC_000023.11deletionPathogenicGRCh38Chr X, 6560264: 8193324
9NC_000023.11deletionPathogenicGRCh38Chr X, 6674278: 7922037
10NC_000023.11deletionPathogenicGRCh38Chr X, 6500268: 7762747

Expression for genes affiliated with Ichthyosis, X-Linked

About this section
Search GEO for disease gene expression data for Ichthyosis, X-Linked.

Pathways for genes affiliated with Ichthyosis, X-Linked

About this section

GO Terms for genes affiliated with Ichthyosis, X-Linked

About this section

Biological processes related to Ichthyosis, X-Linked according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1post-translational protein modificationGO:00436879.5ARSH, STS, SUMF1

Sources for Ichthyosis, X-Linked

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet