MCID: IDP010
MIFTS: 61

Idiopathic Generalized Epilepsy malady

Categories: Genetic diseases (common), Neuronal diseases

Aliases & Classifications for Idiopathic Generalized Epilepsy

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Aliases & Descriptions for Idiopathic Generalized Epilepsy:

Name: Idiopathic Generalized Epilepsy 11 27 13 68
Epilepsy, Generalized 39 68
 
Epilepsy, Idiopathic Generalized 50
Generalised Epilepsy 11

Characteristics:


Classifications:



External Ids:

Disease Ontology11 DOID:1827
MeSH39 D004829
NCIt45 C3021

Summaries for Idiopathic Generalized Epilepsy

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Disease Ontology:11 An epilepsy syndrome that is characterised by generalised seizures with no apparent cause which arise from many independent foci (multifocal epilepsies) or from epileptic circuits that involve the whole brain.

MalaCards based summary: Idiopathic Generalized Epilepsy, also known as epilepsy, generalized, is related to epilepsy, generalized, with febrile seizures plus, type 5 and epilepsy, generalized, with febrile seizures plus, type 2, and has symptoms including seizures, non-epileptic convulsion and seizures. An important gene associated with Idiopathic Generalized Epilepsy is SCN1A (Sodium Voltage-Gated Channel Alpha Subunit 1), and among its related pathways are Benzodiazepine Pathway, Pharmacodynamics and Potassium Channels. Affiliated tissues include brain, cortex and temporal lobe, and related mouse phenotypes are Increased shRNA abundance (Z-score > 2) and Resistant to vaccinia virus (VACV-A4L) infection.

Wikipedia:71 Idiopathic generalized epilepsy (IGE) is a group of epileptic disorders that are believed to have a... more...

Related Diseases for Idiopathic Generalized Epilepsy

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Diseases in the Idiopathic Generalized Epilepsy family:

Epilepsy, Idiopathic Generalized 9 Epilepsy Idiopathic Generalized 8
Epilepsy, Idiopathic Generalized 11 Epilepsy, Idiopathic Generalized 3
Epilepsy, Idiopathic Generalized 5 Epilepsy, Idiopathic Generalized 2
Epilepsy, Idiopathic Generalized 7 Epilepsy, Idiopathic Generalized 14

Diseases related to Idiopathic Generalized Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1epilepsy, generalized, with febrile seizures plus, type 530.9CACNB4, CHRNA4, CLCN2, EFHC1, GABRA1, GABRB3
2epilepsy, generalized, with febrile seizures plus, type 212.0
3epilepsy, generalized, with febrile seizures plus, type 312.0
4epilepsy, idiopathic generalized 911.7
5epilepsy, idiopathic generalized 1111.6
6epilepsy, childhood absence 611.6
7childhood absence epilepsy11.2
8jeavons syndrome11.2
9epilepsy, juvenile myoclonic 511.1
10epilepsy, idiopathic generalized, suscpetibility to, 1211.1
11epilepsy idiopathic generalized 811.1
12myoclonic epilepsy, juvenile 111.0
13epilepsy10.9
14epilepsy, childhood absence 210.8
15photoparoxysmal response 110.8
16epilepsy, juvenile absence 110.8
17epilepsy, childhood absence 510.8
18epileptic encephalopathy, childhood-onset10.8
19generalized epilepsy with febrile seizures plus10.8
20epilepsy, idiopathic generalized 1410.8
21autoimmune thyroid disease 110.2CACNB4, EFHC1
22familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis10.1GABRG2, SCN1A
23adult brain ependymoma10.1EFHC1, SCN1A
24mental retardation, autosomal recessive 3810.1CLCN2, SLC12A5
25familial hemiplegic migraine10.0CACNA1H, CLCN2, EFHC1, GABRA1
26atrial fibrillation, familial, 1310.0SCN1A, SCN1B
27epilepsy with generalized tonic-clonic seizures10.0
28marek disease10.0SCN1A, SLC12A5
29syne1-related autosomal recessive cerebellar ataxia10.0SCN1A, SCN1B
30cerebritis10.0
31neuronitis10.0
32epidermolysis bullosa simplex, ogna type9.9KCNQ2, KCNQ3
33mbd5 haploinsufficiency9.9KCNQ2, KCNQ3
34syphilitic spinal sclerosis9.9KCNQ2, SCN1A
35osteitis fibrosa9.9GABRG2, KCNQ3
36gingivitis9.9GABRG2, SCN1A, SCN1B
37status epilepticus9.9
38spondylosis9.9CHRNA4, GABRD, GABRG2, SCN1A
39suppurative cholangitis9.9KCNQ2, KCNQ3
40temporal lobe epilepsy9.9
41myoclonus9.9
42wagro syndrome9.8GABRG2, KCNQ2, KCNQ3
43adolescence-adult electroclinical syndrome9.8KCNQ2, KCNQ3, SCN1A
44myoclonus epilepsy9.8
45autosomal recessive nonsyndromic deafness9.8GABRA1, GABRB3, GABRG2, KCNQ2, SCN1A
46early onset absence epilepsy9.8GABRG2, KCNQ2, SCN1A, SCN1B
47gingival disease9.7KCNQ2, KCNQ3
48schizophrenia9.6
49obsessive-compulsive disorder9.6
50ocular motor apraxia9.6

Graphical network of the top 20 diseases related to Idiopathic Generalized Epilepsy:



Diseases related to idiopathic generalized epilepsy

Symptoms & Phenotypes for Idiopathic Generalized Epilepsy

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Human phenotypes related to Idiopathic Generalized Epilepsy:

 64
id Description HPO Frequency HPO Source Accession
1 generalized tonic-clonic seizures64 HP:0002069
2 absence seizures64 HP:0002121
3 generalized myoclonic seizures64 HP:0002123
4 eeg with spike-wave complexes (>3.5 hz)64 HP:0010849

UMLS symptoms related to Idiopathic Generalized Epilepsy:


seizures, non-epileptic convulsion

GenomeRNAi Phenotypes related to Idiopathic Generalized Epilepsy according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-1929.1EFHC1, KCNJ10, ME2, SLC12A5
2GR00351-A-18.3CACNB4, CLCN2, EFHC1, GABRA1, KCNQ2, SCN1A

MGI Mouse Phenotypes related to Idiopathic Generalized Epilepsy according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053777.6CACNB4, GABRA1, GABRB3, GABRD, KCNJ10, SLC12A5
2MP:00053896.8CACNB4, CLCN2, GABRA1, GABRB3, GABRD, GABRG2
3MP:00053786.4CACNA1H, CACNB4, GABRA1, GABRB3, GABRG2, KCNJ10
4MP:00107685.7CACNB4, CHRNA4, GABRA1, GABRB3, GABRD, GABRG2
5MP:00053864.9CACNA1H, CACNB4, CHRNA4, CLCN2, EFHC1, GABRA1
6MP:00036314.7CACNA1H, CACNB4, CHRNA4, CLCN2, EFHC1, GABRA1

Drugs & Therapeutics for Idiopathic Generalized Epilepsy

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Drugs for Idiopathic Generalized Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 281)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Carbamazepineapproved, investigationalPhase 4, Phase 3, Phase 2132298-46-42554
Synonyms:
2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaene-2-carboxamide
298-46-4
5-Carbamoyl-5H-dibenz(b,f)azepine
5-Carbamoyl-5H-dibenz[b,F]azepine
5-Carbamoyl-5H-dibenz[b,f]azepine
5-Carbamoyl-5H-dibenzo(b,F)azepine
5-Carbamoyl-5H-dibenzo(b,f)azepine
5-Carbamoyldibenzo(b,f)azepine
5-Carbamyl-5H-dibenzo(b,F)azepine
5-Carbamyl-5H-dibenzo(b,f)azepine
5-Carbamyldibenzo(b,f)azepine
5H-Dibenz(b,F)azepine-5-carboxamide
5H-Dibenz(b,f)azepine-5-carboxamide
5H-Dibenz[b,f]azepine-5- carboxamide
5H-Dibenz[b,f]azepine-5-carboxamide
5H-Dibenzo[b,f]azepine-5-carboxamide
85756-57-6 (di-hydrate)
AC-10560
AC1L1DXT
AC1Q4ZSU
AC1Q4ZSV
AKOS003235644
Amizepin
Amizepine
Apo-Carbamazepine
Atretol
BIDD:GT0479
BIM-0050280.0001
BPBio1_000225
BRD-K71799949-001-06-7
BRN 1246090
BSPBio_000203
BSPBio_001929
Bio-0751
Bipotrol
Biston
C 4024
C06868
C4024_SIAL
C4024_SIGMA
C8981_SIAL
CARBAMAZEPINE, U.S.P.
CAS-298-46-4
CBChromo1_000350
CBZ
CDS1_002710
CHEBI:3387
CHEMBL108
CID2554
CPD001227191
Calepsin
Carbamazepan
Carbamazepen
Carbamazepin
Carbamazepina
Carbamazepina [INN-Spanish]
Carbamazepine (JP15/USP/INN)
Carbamazepine [USAN:INN:BAN:JAN]
Carbamazepinum
Carbamazepinum [INN-Latin]
Carbamazépine
Carbamezepine
Carbatrol
Carbatrol extended-release
Carbazepin
Carbazepine
Carbelan
ChemDiv1_018966
D00252
DB00564
DivK1c_000388
DivK1c_003750
EINECS 206-062-7
EU-0100292
Epitol
Epitol, Equetro, Tegretol, Biston, Calepsin, Carbamazepine
Equetro
Equetro (TN)
Finlepsin
G 32883
G-32883
Geigy 32883
HMS1568K05
 
HMS1920I17
HMS2090M07
HMS2091O19
HMS501D10
HMS640O02
HSDB 3019
I06-0863
IDI1_000388
KBio1_000388
KBio2_000516
KBio2_003084
KBio2_005652
KBio3_001149
KBioGR_000724
KBioSS_000516
Karbamazepin
LS-60362
Lexin
Lopac-C-4024
Lopac0_000292
MLS000069652
MLS001055475
MLS001074172
MolPort-000-710-574
NCGC00015234-01
NCGC00015234-02
NCGC00015234-03
NCGC00015234-07
NCGC00015234-13
NCGC00023877-03
NCGC00023877-04
NCGC00023877-05
NCGC00023877-06
NCGC00023877-07
NCGC00023877-08
NINDS_000388
NSC 169864
NSC169864
Neurotol
Neurotop retard
Novo-Carbamaz
Nu-Carbamazepine
Oprea1_790775
Prestwick0_000052
Prestwick1_000052
Prestwick2_000052
Prestwick3_000052
Prestwick_104
S1693_Selleck
SAM002264603
SMR000058201
SMR001227191
SPBio_000170
SPBio_002124
SPD-417
SPECTRUM1500159
STK177357
Sirtal
Spectrum2_000125
Spectrum3_000325
Spectrum4_000262
Spectrum5_000936
Spectrum_000096
Stazepin
Stazepine
Taro-Carbamazepine
Taro-Carbamazepine Cr
Tegretal
Tegretol
Tegretol (TN)
Tegretol Chewtabs
Tegretol Cr
Tegretol-Xr
Telesmin
Teril
Timonil
Trimonil
UNII-33CM23913M
WLN: T C676 BNJ BVZ
ZINC00004785
benzo[b][1]benzazepine-11-carboxamide
carbamazepine
carbamazepine (Tegretol)
nchem.859-comp7
2PiracetamapprovedPhase 4, Phase 3, Phase 21757491-74-9
3
Valproic Acidapproved, investigationalPhase 4, Phase 3, Phase 232799-66-13121
Synonyms:
(N-C3H7)2CHCOOH
(S)-2-propyl-4-pentanoate
(S)-2-propyl-4-pentanoic acid
2 PP (base)
2-N-Propyl-N-valeric acid
2-Propyl-Pentanoate
2-Propyl-Pentanoic acid
2-Propylpentanoate
2-Propylpentanoic Acid
2-Propylpentanoic acid
2-Propylvaleric Acid
2-Propylvaleric acid
2-n-Propyl-n-valeric acid
2-n-propyl-n-valeric acid
2-propyl-pentanoic acid
2-propylvaleric acid
4-Heptanecarboxylic acid
4-heptanecarboxylic acid
76584-70-8 (hydrochloride salt (2:1))
99-66-1
AC1L1F7T
AC1Q2ULA
AI3-10500
APO-divalproex
Abbott 44090
Acide valproique
Acide valproique [INN-French]
Acide valproique [inn-french]
Acido valproico
Acido valproico [INN-Spanish]
Acido valproico [inn-spanish]
Acidum valproicum
Acidum valproicum [INN-Latin]
Acidum valproicum [inn-latin]
Alti-Valproic
Alti-valproic
Apo-valproic
Apo-valproic syrup
Avugane
BIDD:GT0858
BRN 1750447
Baceca
C07185
CHEBI:39867
CHEMBL109
CID3121
CPD000499581
Convulex
Convulsofin
D00399
DB00313
DOM-divalproex
DOM-valproic
DOM-valproic acid E.C.
DPA
Delepsine
Depacon
Depakene
Depakene (TN)
Depakin
Depakin chrono
Depakine
Depakine chrono
Depakote
Depakote (TM)
Deproic
Di-N-propylacetic acid
Di-N-propylessigsaure
Di-N-propylessigsaure [german]
Di-n-propylacetic acid
Di-n-propylessigsaeure
Di-n-propylessigsaure
Di-n-propylessigsaure [German]
Di-n-propylessigsäure
Dipropyl Acetate
Dipropylacetate
Dipropylacetic acid
DivK1c_000273
Divalproex
Dom-Valproic
Dom-valproate
Dom-valproic acid
Dom-valproic acid syrup
EINECS 202-777-3
Epiject I.V.
Epilex
Epilim
Epival
Epival er
Ergenyl
G2M-777
Gen-divalproex
HMS2089J06
HSDB 3582
I04-0211
InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
KBio1_000273
KBio2_001001
KBio2_002277
KBio2_003569
KBio2_004845
 
KBio2_006137
KBio2_007413
KBio3_002626
KBio3_002757
KBioGR_000871
KBioGR_002277
KBioSS_001001
KBioSS_002278
Kyselina 2-propylvalerova
Kyselina 2-propylvalerova [Czech]
LS-161170
LS-2068
MLS001076682
MLS001335927
MLS001335928
MLS002415770
Med Valproic
Med valproic
MolPort-001-791-895
Mylproin
Myproate
Myproic Acid
Myproic acid
N-DPA
N-Dipropylacetic acid
NCGC00091149-01
NCGC00091149-02
NCGC00091149-03
NCGC00091149-04
NINDS_000273
NSC 93819
NSC93819
Novo-Valproic
Novo-Valproic - ECC
Novo-divalproex
Novo-valproic
Novo-valproic soft gel cap
Nu-Valproic
Nu-valproic
P0823
P6273_SIGMA
PEAC
PHL-valproate
PHL-valproic acid
PHL-valproic acid E.C.
PMS-Divalproex
PMS-Valproic Acid
PMS-valproate
PMS-valproic acid
PMS-valproic acid E.C.
Penta-Valproic
Penta-valproic
Propylvaleric acid
Ratio-Valproic - ECC
S(-)-4-En-valproate
S(-)-4-En-valproic acid
S-2-N-Propyl-4-pentenoate
S-2-N-Propyl-4-pentenoic acid
SAM002564230
SBB065764
SMR000499581
SPBio_000912
Sandoz valproic
Savicol
Semisodium Valproate
Sodium hydrogen divalproate
Spectrum2_000946
Spectrum3_001733
Spectrum4_000376
Spectrum_000521
Sprinkle
Stavzor
UNII-614OI1Z5WI
VALPROIC ACID
VPA
Valcote
Valparin
Valproate
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum seminatricum [Latin]
Valproic Acid, Sodium Salt (2:1)
Valproic acid
Valproic acid (USP)
Valproic acid USP
Valproic acid USP24
Valproic acid [USAN:INN:BAN]
Valproic acid [usan:ban:inn]
Valproinsaeure
Valproinsäure
Vupral
WLN: QVY3 & 3
acide valproïque
acidum valproicum
di-n-propylacetic acid
n-DPA
n-Dipropylacetic acid
nchembio.79-comp4
nchembio815-comp21
valproate
valproic acid
ácido valproico
4
DopamineapprovedPhase 4, Phase 2383651-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
5
Lamotrigineapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 118584057-84-13878
Synonyms:
3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine
3,5-diamino-6-(2,3-dichlorophenyl)- as -triazine
6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diyldiamine
6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
84057-84-1
AC-10298
AC1L1GWT
BIDD:GT0794
BW 430C
BW-430C
Bio-0056
C047781
CHEBI:138727
CHEBI:6367
CHEMBL741
CID3878
CPD000058464
Crisomet
D00354
DB00555
Desitin Brand of Lamotrigine
EINECS 281-901-8
EU-0100688
EUR-1048
Faes Brand of Lamotrigine
GI 267119X
GW 273293
Glaxo Wellcome Brand of Lamotrigine
GlaxoSmithKline Brand of Lamotrigine
HMS2051C10
HMS2089M08
HMS2093P21
HSDB 7526
Juste Brand of Lamotrigine
L 3791
L3791_SIGMA
LS-155249
 
Labileno
Lamictal
Lamictal (TN)
Lamictal CD
Lamictal Cd
Lamictal ODT
Lamictal XR
Lamictin
Lamiktal
Lamitor
Lamotrigina
Lamotrigina [Spanish]
Lamotrigine
Lamotrigine (JAN/USAN/INN)
Lamotrigine [USAN:INN:BAN]
Lamotriginum
Lamotriginum [Latin]
Lopac-L-3791
Lopac0_000688
MLS000069685
MLS000759486
MLS001077325
MolPort-003-666-744
NCGC00015605-01
NCGC00015605-02
NCGC00015605-06
NCGC00015605-08
NCGC00022936-02
NCGC00022936-04
NCGC00022936-05
NSC746307
SAM001246697
SMP2_000303
SMR000058464
STK628377
Tocris-1611
UNII-U3H27498KS
ZINC00013156
lamotrigine
6
Clonazepamapproved, illicitPhase 4, Phase 3321622-61-32802
Synonyms:
1,3-Dihydro-5-(o-chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2-one
1,3-Dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one
1,3-dihydro-7-Nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one
106955-87-7
1622-61-3
5-(2-Chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one
5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one
5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
5-(2-Chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
5-(2-Chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2(1H)-one
5-(2-chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one
5-(O-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
5-(o-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one
5-(o-Chlorophenyl)-7-nitro-1H-1,4-benzodiazepin-2(3H)-one
5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
5-24-04-00351 (Beilstein Handbook Reference)
7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one
AC-15733
AC1L1EI2
Alti-Clonazepam
Antelepsin
Antilepsin
BAS 00308658
BIDD:PXR0144
BRN 0759557
C1277_SIGMA
C15H10ClN3O3
CHEBI:3756
CHEMBL452
CID2802
CLONAZEPAM
Chlonazepam
Cloazepam
Clonazepam (JP15/USP/INN)
Clonazepam [USAN:INN:BAN:JAN]
Clonazepamum
Clonazepamum [INN-Latin]
Clonex
Clonopin
D00280
D002998
DB01068
DEA No. 2737
 
DF2374250
DivK1c_000973
EINECS 216-596-2
HMS2093H22
HMS503C07
HSDB 3265
I14-1364
IDI1_000973
Iktorivil
Jsp003251
KBio1_000973
Kenoket
Klonopin
Klonopin (TN)
Klonopin Rapidly Disintegrating
LS-34156
LS-34260
Landsen
Lktorivil
Lonazep
Melzap
MolPort-001-729-088
NINDS_000973
NIOSH/DF2374250
NSC 179913
NSC179913
Oprea1_168772
Paxam
RO4023
Ravotril
Rivatril
Rivoril
Rivotril
Ro 4-8180
Ro 4023
Ro 5-4023
Ro 5-4023/B-7
Ro 54023
Ro-5-4023
Solfidin
UNII-5PE9FDE8GB
WLN: T67 GMV JN IHJ CNW KR BG
ZINC03813003
clonazepam
7
Midazolamapproved, illicitPhase 4, Phase 3, Phase 2, Phase 172359467-70-84192
Synonyms:
4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate
59467-70-8
8-Chlor-6-(2-fluorphenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepin
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5a][1,4]benzodiazepine hydrochloride
8-Chloro-6-(O-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]-benzodiazepine
8-Chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine
AC-18749
AC1L1HMA
BIDD:GT0647
BRN 0625572
Buccolam
C07524
C18H13ClFN3
CHEMBL655
CID4192
D00550
DB00683
DEA No. 2884
Dazolam
Dea No. 2884
 
Dormicum
Dormicum (TN)
EINECS 261-774-5
LS-77780
Midanium
Midazolam
Midazolam (JAN/INN)
Midazolam Base
Midazolam Hcl
Midazolam [INN:BAN:JAN]
Midazolamum
Midazolamum [INN-Latin]
Midosed
MolPort-003-849-219
NCGC00168254-01
Ro 21-3981
TL8003787
UC429_SIGMA
UNII-R60L0SM5BC
Versed
ZINC00001732
midazolam
nchembio747-comp32
8
TopiramateapprovedPhase 4, Phase 3, Phase 2, Phase 124997240-79-45284627
Synonyms:
-D-fructopyranose deriv.
.beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate (9CI)
2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene) .beta.-D-fructopyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
2,3:4,5-Di- O -isopropylidene-(beta)-D-fructopyranose sulfamate
2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamate
5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran, .beta.
97240-79-4
AKOS000424547
BIDD:GT0854
BIDD:PXR0127
BRN 5988957
BSPBio_002306
C052342
C07502
C12H21NO8S
CBChromo1_000352
CHEBI:129573
CHEMBL220492
CID5284627
CPD000466325
Cilag brand of topiramate
D00537
DB00273
Epitoma
Epitomax
HMS1922H06
HMS2051L09
HMS2093D20
HSDB 7531
Janssen brand of topiramate
KS-1122
KW-6485
LS-187392
LS-69764
MLS000759431
MLS001424070
McN 4853
McN-4853
MolPort-001-615-062
MolPort-002-885-869
NCGC00178714-01
 
Ortho brand of topiramate
RWJ 17021
RWJ-17021
RWJ-17021-000
S1438_Selleck
SAM001246601
SMR000466325
SPBio_000995
SPECTRUM1505801
STOCK1N-71037
Spectrum2_001128
T0575_SIGMA
TL8006021
TOR
TPM
Tipiramate
Tipiramate [French]
Tipiramato
Tipiramato [Spanish]
Topamac
Topamax
Topamax (TN)
Topamax Sprinkle
Topamax, Topiramate
Topimax
Topina
Topiramate
Topiramate (JAN/USAN/INN)
Topiramate (TPM)
Topiramate / Placebo
Topiramate [USAN:BAN:INN]
Topiramato
Topiramato [INN-Spanish]
Topiramatum
Topiramatum [INN-Latin]
Topiramic acid
Topomax
UNII-0H73WJJ391
USL-255
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
topiramate
topiramate tablet
topiramatum [Latin]
9
Propofolapproved, investigational, vet_approvedPhase 4, Phase 3, Phase 210822078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
10
Methylphenidateapproved, investigationalPhase 4375113-45-14158
Synonyms:
.alpha.-Phenyl-2-piperidineacetic acid methyl ester
113-45-1
2-Piperidineacetic acid, .alpha.-phenyl-, methyl ester
2-Piperidineacetic acid, alpha-phenyl-, methyl ester
298-59-9 (hydrochloride)
4311/B Ciba
AC1L1HJM
C 4311
C07196
CHEBI:6887
CHEMBL796
CID4158
Calocain
Centedein
Centedrin
Centedrine
Centredin
Concerta
D-Methylphenidate HCl
D04999
DB00422
DB06701
DEA No. 1724
Daytrana
Daytrana (TN)
EINECS 204-028-6
Focalin
Focalin XR
HSDB 3126
L001307
LS-565
METHYLPHENIDATE (SEE ALSO: METHYLPHENIDATE HYDROCHLORIDE, CAS 298-59-9, NTPNO 10266-R)
MPH
Meridil
Metadate
Metadate CD
Metadate ER
MethyPatch
Methyl (2-phenyl-2-(2-piperidyl)acetate)
Methyl alpha-phenyl-alpha-(2-piperidyl)acetate
Methyl alpha-phenyl-alpha-2-piperidinylacetate
Methyl phenidate
 
Methyl phenidyl acetate
Methyl phenidylacetate
Methylfenidan
Methylin
Methylin ER
Methylofenidan
Methylphen
Methylphenidan
Methylphenidate
Methylphenidate (USAN/INN)
Methylphenidate HCl
Methylphenidate [INN:BAN]
Methylphenidate hydrochloride
Methylphenidatum
Methylphenidatum [INN-Latin]
Methylphenidylacetate hydrochloride
Methypatch
Metilfenidat hydrochloride
Metilfenidato
Metilfenidato [INN-Spanish]
Metilfenidato [Italian]
MolPort-001-779-620
NCI-C56280
PMS-Methylphenidate
Phenidylate
Plimasine
Riphenidate
Ritalin
Ritalin LA
Ritalin SR
Ritalin hydrochloride
Ritalin-SR
Ritaline
Ritcher Works
Ritcher works
Tsentedrin
UNII-207ZZ9QZ49
alpha-Phenyl-2-piperidineacetic acid methyl ester
alpha-Phenyl-alpha-(2-piperidyl)acetic acid methyl ester
d-methylphenidate HCl
methyl 2-phenyl-2-piperidin-2-ylacetate
methyl phenyl(piperidin-2-yl)acetate
methylphenidate
nchembio.2007.55-comp28
11
CitalopramapprovedPhase 451259729-33-82771
Synonyms:
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
1,3-dihydro[3,4]benzofuran-5-carbonitrile
1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
59729-33-8
AB00513896
AC-12214
AC1L1EFH
AE-641/00603021
Akarin
BPBio1_000929
BRD-A47598013-004-02-0
BSPBio_000843
Bonitrile
C07572
C20H21FN2O
CHEBI:3723
CHEMBL549
CID2771
CPD000465669
Celapram
Celexa
Celius
Ciazil
Cilift
Cipram
Cipramil
Ciprapine
Citabax
Citadur
Citadur (TN)
Citalec
Citalopram (USP/INN)
Citalopram Hydrobromide
Citalopram [Celexa]
Citalopram [INN:BAN]
Citalopram hydrobromide
Citalopramum
Citalopramum [INN-Latin]
 
Citol
Citopam
Citox
Citrol
Cytalopram
D07704
DB00215
Dalsan
EINECS 261-891-1
Elopram
HMS2090O09
HMS2093A14
Humorup
I01-0382
InChI=1/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
L001223
LS-84327
Lopac0_000258
Lu 10-171
Lu-10-171
MolPort-003-666-794
NCGC00015267-07
NCGC00025160-02
Nitalapram
Oropram
Pramcit
Prestwick3_000692
Recital
SAM002589960
ST069372
STL058639
Seropram
Talam
Talohexal
Temperax
UNII-0DHU5B8D6V
Vodelax
Zentius
Zetalo
[3H]Citalopram
citalopram
12
OxcarbazepineapprovedPhase 4, Phase 2, Phase 35628721-07-534312
Synonyms:
10,11-Dihydro-10-oxo-5H-debenz(b,f)azepine-5-carboxamide
10,11-Dihydro-10-oxo-5H-dibenz(b,F)azepine-5-carboxamide
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
10,11-Dihydro-10-oxo-5H-dibenzo[b,f]azepine-5-carboxamide
10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide
10-Oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
28721-07-5
5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
AB1004555
AC-3483
AC1L1RCU
AC1Q6NA8
BIDD:GT0078
BSPBio_003457
Bio-0527
C036006
C07492
CHEMBL1068
CID34312
CPD000048684
D00533
DB00776
Desitin brand of oxcarbazepine
EINECS 249-188-8
Epilexter
Epliga
GP 47680
GP-47680
HMS1922H17
HMS2051O04
HMS2090F13
HMS2093E10
HSDB 7524
I06-0072
KBio2_002155
KBio2_004723
KBio2_007291
KBio3_002677
KBioGR_001248
KBioSS_002155
 
KIN-493
LS-60365
MLS000084586
MLS000759520
MLS001201742
MolPort-001-685-316
NCGC00065934-02
NCGC00065934-03
NCGC00065934-04
Novartis brand of oxcarbazepine
O0363
O3764_SIGMA
OCBZ
OXCARBAZEPINE
Oxacarbazepine
Oxcarbamazepine
Oxcarbazepime
Oxcarbazepina
Oxcarbazepina [INN-Spanish]
Oxcarbazepine
Oxcarbazepine (USAN/INN)
Oxcarbazepine [INN]
Oxcarbazepinum
Oxcarbazepinum [INN-Latin]
S1391_Selleck
SAM001246754
SMR000048684
SPBio_000345
SPECTRUM1504243
SPN-804
STK594696
Spectrum2_000483
Spectrum3_001669
Spectrum4_000634
Spectrum5_001869
Spectrum_001675
Timox
Trileptal
Trileptal (TN)
UNII-VZI5B1W380
ZINC00004724
oxcarbazepine
13
LabetalolapprovedPhase 43636894-69-63869
Synonyms:
2-Hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)benzamide
2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide
2-hydroxy-5-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl}benzamide
3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol
36894-69-6
5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide
AB00053659
AC-18747
AC1L1GW8
AH 5158
AH-5158
Albetol
BPBio1_000170
BRD-A07440155-003-05-6
BSPBio_000154
BSPBio_003142
C07063
CHEBI:6343
CHEMBL429
CID3869
D08106
DB00598
DivK1c_000474
EINECS 253-258-3
HSDB 6537
IDI1_000474
Ibidomide
KBio1_000474
KBio2_002087
KBio2_004655
KBio2_007223
 
KBio3_002642
KBioGR_000727
KBioSS_002087
L001344
LS-26936
Labetalol
Labetalol (INN)
Labetalol [INN:BAN]
Labetalolum
Labetalolum [INN-Latin]
Labetolol
Lopac0_000687
MolPort-003-898-140
NCGC00015595-06
NCGC00089800-02
NINDS_000474
NORMOZIDE
Prestwick0_000277
Prestwick1_000277
Prestwick2_000277
Prestwick3_000277
SBB067266
SPBio_000905
SPBio_002373
Sch-19927
Spectrum2_000863
Spectrum3_001581
Spectrum4_000184
Spectrum5_001010
Spectrum_001607
TL8002725
UNII-R5H8897N95
labetalol
14
ClevidipineapprovedPhase 420167221-71-8
Synonyms:
 
Clevidipine butyrate
15
HydralazineapprovedPhase 44586-54-43637
Synonyms:
(1Z)-1(2H)-Phthalazinone hydrazone
(2H)-Phthalazinone hydrazone
1(2H)-Phthalazinone hydrazone
1(2H)-Phthalazinone, hydrazone
1-Hydrazinophthalazine
1-Phthalazinylhydrazine
304-20-1 (mono-hydrochloride)
5-25-17-00412 (Beilstein Handbook Reference)
6-Hydralazine
86-54-4
AC1L1GDN
AC1Q4UY1
AKOS000122609
Apresolin
Apresoline
Apressin
Apressin (pharmaceutical)
Apressoline
Aprezolin
BA 5968
BRD-K82103381-003-03-7
BRN 0132615
BSPBio_002130
C 5968
C-5068
C-5968
C07040
C8H8N4
CAS-304-20-1
CCRIS 5385
CHEBI:5775
CHEMBL276832
CID3637
Ciba 5968
D08044
DB01275
DivK1c_000117
EC-000.1838
EINECS 201-680-3
HLZ
Hidral
Hidral (TN)
Hidralazin
Hidralazina
Hidralazina [INN-Spanish]
Hidralazina [Spanish]
Hipoftalin
Hydralazin
Hydralazine (INN)
Hydralazine [INN:BAN]
Hydralazine hydrochloride
 
Hydralazinum
Hydralazinum [INN-Latin]
Hydrallazin
Hydrallazine
Hydrazinophthalazine
Hydrazone 1(2H)-phthalazinone
Hypophthalin
IDI1_000117
Idralazina
Idralazina [DCIT]
Idralazina [Italian]
InChI=1/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)
KBio1_000117
KBio2_001355
KBio2_003923
KBio2_006491
KBio3_001350
KBioGR_000349
KBioSS_001355
LS-109171
Lopac-H-1753
Lopac0_000593
MolPort-000-876-738
MolPort-001-794-088
NCGC00015501-01
NCGC00015501-02
NCGC00015501-05
NCGC00162199-01
NCIOpen2_001484
NINDS_000117
NSC 126699
NSC126699
Oprea1_207681
Oprea1_416878
Phthalazin-1-ylhydrazine
Praparat 5968
Prestwick0_000169
Prestwick1_000169
Prestwick2_000169
SPBio_000977
SPBio_001958
ST50512087
Spectrum2_000969
Spectrum3_000455
Spectrum4_000005
Spectrum5_000822
Spectrum_000875
UNII-26NAK24LS8
WLN: T66 CNNJ BMZ
ZINC12360535
[2H-Phthalazin-(1Z)-Ylidene]-Hydrazine Hydrochloride
hydralazine
phthalazin-1-ylhydrazine
16
TiagabineapprovedPhase 420115103-54-360648
Synonyms:
(-)-(R)-1-(4,4-Bis(3-methyl-2-thienyl)-3-butenyl)nipecotic acid
(3R)-1-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]piperidine-3-carboxylic acid
(3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid
115103-54-3
A-70569-1
ABBOTT-70569-1
AC-7048
AC1L1TNE
AC1Q5R43
BIDD:GT0018
C07503
C20H25NO2S2
CHEBI:222170
CHEMBL1027
CID60648
D08588
DB00906
 
Gabitril
Gabitril (TN)
HSDB 7527
LS-114651
N-(4,4-di(3-methylthien-2-yl)but-3-enyl)nipecotic acid
NCGC00164626-01
NO 329
NO-328
NO-329
Tiagabina
Tiagabina [INN-Spanish]
Tiagabine (INN)
Tiagabine [INN:BAN]
Tiagabine [INN]
Tiagabinum
Tiagabinum [INN-Latin]
UNII-Z80I64HMNP
tiagabine
17
Pregabalinapproved, illicit, investigationalPhase 4, Phase 3361148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
18
Dexmedetomidineapproved, vet_approvedPhase 459276631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
19
VigabatrinapprovedPhase 4, Phase 32168506-86-5, 60643-86-95665
Synonyms:
( inverted question mark)-gamma-Vinyl GABA
(?)-gamma-Vinyl GABA
(R,S)-4-Amino-5-hexenoic acid
.gamma.-Vinyl-.gamma.-aminobutyric acid
.gamma.-Vinyl-GABA
4-Amino-5-hexenoic acid
4-Aminohexenoic acid
4-aminohex-5-enoic acid
60643-86-9
74046-07-4
AB00053309
AC1L1KUZ
Acid, gamma-Vinyl-gamma-Aminobutyric
Aventis Brand of Vigabatrin
BPBio1_000465
BPBio1_000925
BSPBio_000421
BSPBio_003469
Biomol-NT_000247
C07500
C6H11NO2
CHEBI:241484
CHEMBL89598
CID5665
CPP-109
D00535
D020888
DB01080
DivK1c_006760
EU-0101277
GVG
Gamma vinyl GABA
HMS1569F03
HMS2094M21
Hexenoic acid, 4-amino
Hoechst Brand of Vigabatrin
KBio1_001704
KBio2_000848
KBio2_003416
KBio2_005984
KBio3_002973
KBioSS_000848
LS-75569
Lopac0_001277
M071754
MDL 71,754
MDL 71754
 
MDL-71754
MolPort-003-666-796
NCGC00016087-03
NCGC00016087-08
NCGC00024802-02
NCGC00024802-03
NCGC00024802-04
NCGC00024802-05
NCGC00024802-06
Prestwick0_000501
Prestwick1_000501
Prestwick2_000501
Prestwick3_000501
Prestwick_837
RMI 71754
RMI-71754
RMI-71890
SPBio_002342
SPECTRUM1502036
Sabril
Sabril (TN)
Sabrilex
SpecPlus_000664
Spectrum3_001825
Spectrum_000368
V 8261
V8261_SIGMA
Vigabatrin
Vigabatrin (JAN/USAN/INN)
Vigabatrin Aventis Brand
Vigabatrin Hoechst Brand
Vigabatrin Yamanouchi Brand
Vigabatrin [USAN:BAN:INN]
Vigabatrin [USAN:INN:BAN]
Vigabatrina
Vigabatrina [Spanish]
Vigabatrine
Vigabatrine [French]
Vigabatrinum
Vigabatrinum [Latin]
Vinyl gamma-aminobutyric acid
Yamanouchi Brand of Vigabatrin
gamma Vinyl GABA
gamma Vinyl gamma Aminobutyric Acid
gamma-Vinyl GABA
gamma-Vinyl-GABA
gamma-Vinyl-gamma-Aminobutyric Acid
gamma-Vinyl-gamma-aminobutyric acid
vigabatrin
20
SertralineapprovedPhase 429979617-96-268617
Synonyms:
(+)-Sertraline
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
(1S,4S)-sertraline
(1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
(1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
(1S-cis)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine
79559-97-0 (Hydrochloride)
79617-96-2
AB00514002
AB1004870
AC-15639
AC1L2A41
AC1Q3O5N
AC1Q3XJU
Apo-Sertraline
BIDD:GT0768
BIDD:PXR0193
BPBio1_001285
BRD-K82036761-003-02-1
BRN 5753709
BSPBio_001167
BSPBio_002698
C07246
C17H17Cl2N
CHEBI:9123
CHEMBL809
CID68617
Cp 51974
D02360
DB01104
DB08567
FT-0081122
HSDB 7037
KBio3_001918
 
KBioGR_001724
LS-94179
Lustral
MLS001195647
MLS002222308
MolPort-002-885-860
NCGC00092386-03
NCGC00092386-04
NCGC00092386-05
NCGC00092386-06
NCGC00092386-07
NCGC00092386-08
NCGC00092386-09
Prestwick3_001014
SMR000596516
SPBio_000385
SRE
Sertralina
Sertralina [Spanish]
Sertraline
Sertraline (INN)
Sertraline Hydrochloride
Sertraline [INN:BAN]
Sertraline [Zoloft]
Sertraline hydrochloride
Sertralinum
Sertralinum [Latin]
Spectrum2_000493
Spectrum3_001079
Spectrum4_001232
Sultamicillin Tosylate
UNII-QUC7NX6WMB
Zoloft
cis-(+)-sertraline
sertraline
sertraline (Zoloft)
21
Eslicarbazepine acetateapprovedPhase 4, Phase 36775970-99-9, 236395-14-5123618
Synonyms:
(10S)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
(10S)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate
10-Acetoxy-10,11-dihydro-5H-dibenz(b,f)azepine-5-carboxamide
236395-14-5
AC1L452K
AKOS005145781
B5435_SIGMA
BIA 2-093
BIA-2-093
CHEBI:239940
CHEMBL87992
CID179344
 
ESL
Erelib
Eslicarbazepine acetate
Exalief
MolPort-005-942-413
NCGC00165752-01
NCGC00165752-02
Pazzul
S-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
SEP-0002093
Stedesa
ZINC00007295
Zebinix
[(5S)-11-carbamoyl-5,6-dihydrobenzo[b][1]benzazepin-5-yl] acetate
22
Zonisamideapproved, investigationalPhase 4, Phase 36868291-97-45734
Synonyms:
1,2-Benzisoxazole-3-methanesulfonamide
1,2-benzoxazol-3-ylmethanesulfonamide
1-(1,2-Benzoxazol-3-Yl)methanesulfonamide
1-(1,2-benzisoxazol-3-yl)methanesulfonamide
3-(Sulfamoylmethyl)-1,2-benzisoxazole
3-sulfamoylmethyl-1,2-benzisoxazole
68291-97-4
AC-1413
AC1L1L0Q
AC1Q55GQ
AD 810
AD-810
AD-810N
AKOS001312269
BIDD:GT0708
BIDD:PXR0183
BRD-K48300629-001-03-8
BRN 1077076
Benzo[d]isoxazol-3-yl-methanesulfonamide
Bio-0532
C022189
C07504
C8H8N2O3S
CHEBI:10127
CHEMBL750
CI 912
CI-912
CID5734
CPD000596519
D00538
DB00909
E-2090
Elan brand of zonisamide
Exceglan
 
Excegram
Excegran
Excegran (TN)
FT-0082702
HMS2089O07
HSDB 7293
I06-0495
LS-33637
MLS001195632
MLS001306491
MolPort-002-507-855
NCGC00159319-02
NCGC00159319-03
PD 110843
PD-110843
S1445_Selleck
SAM002548957
SMR000596519
SPR_2
STK711131
Tremode
Trerief
UNII-459384H98V
ZINC00004321
Zonegran
Zonegran, Zonisamide
Zonisamida
Zonisamida [Spanish]
Zonisamide (JAN/USAN/INN)
Zonisamide (ZNS)
Zonisamide [USAN:BAN:INN:JAN]
Zonisamidum
Zonisamidum [Latin]
zonisamide
zonisamide monosodium
23
Gabapentinapproved, investigationalPhase 430360142-96-33446
Synonyms:
1-(Aminomethyl)-cyclohexaneacetic acid
1-(Aminomethyl)cyclohexaneacetic acid
2-[1-(aminomethyl)cyclohexyl]acetic acid
60142-96-3
AC-1485
AC1L1FYE
AC1Q53PH
AKOS000280865
Aclonium
Apo-Gabapentin
Apotex brand of gabapentin
Aventis brand of gabapentin
BB_SC-1512
BIDD:GT0656
BPBio1_000993
BRN 2359739
BSPBio_000901
C040029
C9H17NO2
CAS-60142-96-3
CCRIS 7210
CHEBI:188316
CHEBI:42797
CHEMBL940
CI 945
CI-945
CID3446
D00332
DB00996
DDS-2003
DM-1796
DM-5689
EINECS 262-076-3
EU-0100582
G-154
G0318
G154_SIGMA
GBN
GOE 2450
Gabapen
Gabapentin
Gabapentin (JAN/USAN/INN)
Gabapentin GR
Gabapentin Hexal
Gabapentin Stada
Gabapentin [USAN:INN:BAN]
Gabapentin-ratiopharm
Gabapentina
Gabapentine
Gabapentine [INN-French]
Gabapentino
Gabapentino [INN-Spanish]
Gabapentino [Spanish]
Gabapentinum
 
Gabapentinum [INN-Latin]
Gabapetin
Go 3450
Goe-3450
HMS1570N03
HMS2089J03
HSDB 7364
Hexal brand of gabapentin
I06-0677
L000733
LS-7194
Lopac-G-154
Lopac0_000582
MLS000069358
MolPort-000-883-862
NCGC00015466-01
NCGC00015466-02
NCGC00015466-06
NCGC00015466-09
NCGC00016891-01
NCGC00021545-02
NCGC00021545-04
NCGC00021545-05
NSC742194
Neurontin
Neurontin (TN)
Novo-Gabapentin
Novo-Gabapentine
Novopharm brand of gabapentin
PMS-Gabapentin
Parke Davis brand of gabapentin
Pfizer brand of gabapentin
Pharmascience brand of gabapentin
Prestwick0_000861
Prestwick1_000861
Prestwick2_000861
Prestwick3_000861
Prestwick_151
S2133_Selleck
SMR000058311
SPBio_002822
STK598009
Serada
Stadapharm brand of gabapentin
TL8003814
Tocris-0806
UNII-6CW7F3G59X
Vultin
Warner-Lambert brand of gabapentin
[1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID
gabapentin
gabapentin (Neurontin)
gabapentina
gabapentinium
ratiopharm brand of gabapentin
24
Butyric AcidexperimentalPhase 4380107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
1-propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
Butyric acid
 
Butyricum acidum
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
N-butanoic acid
N-butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
25Autonomic AgentsPhase 4, Phase 3, Phase 2, Phase 110150
26AnticonvulsantsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 12695
27Hypnotics and SedativesPhase 4, Phase 3, Phase 2, Phase 12616
28Anesthetics, GeneralPhase 4, Phase 3, Phase 2, Phase 12934
29Dopamine AgentsPhase 4, Phase 23836
30Antiparkinson AgentsPhase 4, Phase 21574
31AnestheticsPhase 4, Phase 3, Phase 2, Phase 19596
32Anesthetics, IntravenousPhase 4, Phase 3, Phase 2, Phase 12538
33Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 26501
34AnalgesicsPhase 4, Phase 3, Phase 211733
35Tranquilizing AgentsPhase 4, Phase 3, Phase 2, Phase 14265
36Cytochrome P-450 CYP3A InducersPhase 4, Phase 3, Phase 2, Phase 11119
37EtiracetamPhase 4, Phase 3, Phase 2207
38Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 123689
39Nootropic AgentsPhase 4, Phase 3, Phase 2716
40Psychotropic DrugsPhase 4, Phase 3, Phase 2, Phase 16430
41Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 118340
42Neuroprotective AgentsPhase 4, Phase 3, Phase 2, Phase 11716
43Anti-Obesity AgentsPhase 4, Phase 3, Phase 2, Phase 1413
44Protective AgentsPhase 4, Phase 3, Phase 2, Phase 17443
45Central Nervous System DepressantsPhase 4, Phase 3, Phase 2, Phase 113403
46GABA ModulatorsPhase 4, Phase 3, Phase 2, Phase 1904
47GABA AgentsPhase 4, Phase 3, Phase 2, Phase 11684
48calcium channel blockersPhase 4, Phase 3, Phase 2, Phase 11985
49Antimanic AgentsPhase 4, Phase 3, Phase 2814
50Excitatory Amino AcidsPhase 4, Phase 3, Phase 2, Phase 11362

Interventional clinical trials:

(show top 50)    (show all 382)
idNameStatusNCT IDPhase
1Topiramate Treatment for Patients With Epilepsy and Learning Disability : A Prospective Observational StudyUnknown statusNCT00956696Phase 4
2The Benefit of Prophylactic Anticonvulsant in Post Cardiac Arrest Syndrome With Induced Mild HypothermiaUnknown statusNCT01083784Phase 4
3A Study to Evaluate the Dosing, Effectiveness and Safety of Topiramate for the Treatment of EpilepsyCompletedNCT00266604Phase 4
4The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled StudyCompletedNCT02208492Phase 4
5Treatment Of Primary Generalized Tonic-Clonic Seizures With An Investigational New DrugCompletedNCT00043901Phase 4
6Trial of Levetiracetam in Patients With Primary Brain Tumors and Symptomatic Seizures Who Undergo SurgeryCompletedNCT00571155Phase 4
7Levetiracetam Versus Oxcarbazepine as Monotherapy to Evaluate Efficacy and Safety in Subjects With Newly or Recently Diagnosed Partial EpilepsyCompletedNCT01498822Phase 4
8Escitalopram Treatment of Major Depression in Patients With Temporal Lobe EpilepsyCompletedNCT00595699Phase 4
9A Study to Assess Tolerability and Efficacy of Topiramate Monotherapy in Recently Diagnosed Patients With EpilepsyCompletedNCT01689649Phase 4
10A Pilot Study to Evaluate Efficacy and Safety of Clevidipine in Neurosurgical PatientsCompletedNCT00952081Phase 4
11Switching From an SSRI to Tiagabine(GABITRIL) in Order to Alleviate SSRI Induced Sexual DysfunctionCompletedNCT00174850Phase 4
12Methylphenidate for Treating Attention Deficit Hyperactivity Disorder in Children With Both ADHD and EpilepsyCompletedNCT00323947Phase 4
13UCB Antiepileptic Drugs (AED) Pregnancy Registry (Formerly the Keppra® Pregnancy Registry)CompletedNCT00345475Phase 4
14Non-Interventional Study With LYRICA (Pregabalin) In Patients With Epilepsy As Adjunctive Therapy Of Partial Seizures To Reduce Seizure FrequencyCompletedNCT00684424Phase 4
15A Study to Evaluate the Safety and Efficacy of Zonisamide an Antiepileptic Drug as Monotherapy or Adjunctive Therapy in Treatment of Adult Patients With Partial, Generalized or Combined Seizures.CompletedNCT01283256Phase 4
16A Prospective, Observational Study On The Effectiveness Of New Antiepileptic Drugs As First Bitherapy In The Daily Clinical PracticeCompletedNCT00855738Phase 4
17Lyrica (Pregabalin) Administered as an Add-on Therapy for Partial Seizures (LEADER).CompletedNCT00288639Phase 4
18Safety and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy for Partial Seizures in Elderly PatientsCompletedNCT01422720Phase 4
19Comparative Study of Zonisamide and Carbamazepine as an Initial Monotherapy: Efficacy and Safety EvaluationCompletedNCT01127256Phase 4
20Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial SeizuresCompletedNCT00537940Phase 4
21Open Label, Zonegran (Zonisamide) In Partial Onset SeizuresCompletedNCT00215592Phase 4
22Treatments for Psychogenic Nonepileptic Seizures (NES)CompletedNCT00159965Phase 4
23Trial Evaluating the Efficacy and Safety of Perampanel Added to Monotherapy in Participants With Partial Onset SeizuresRecruitingNCT02726074Phase 4
24Evaluation of Neuroinflammation in Children With Infantile SpasmsRecruitingNCT02092883Phase 4
25Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or PlaceboRecruitingNCT00351611Phase 4
26A Pilot Study of Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance ImagingRecruitingNCT02633241Phase 4
27Efficacy and Safety of Intramuscular Midazolam Compared to Buccal Midazolam in Pediatric SeizuresRecruitingNCT02897856Phase 4
28A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With EnzalutamideActive, not recruitingNCT01977651Phase 4
29Comparison of Oral 30 % Dextrose and iv Midazolam Sedation During MRI in NeonatesActive, not recruitingNCT02645279Phase 4
30Does Pregabalin Improve Symptoms of Anxiety in Patients With Epilepsy? A Comparison With SertralineTerminatedNCT01309074Phase 4
31Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy PatientsTerminatedNCT00522418Phase 4
32Trial to Assess Vagus Nerve Stimulation Therapy vs. Anti-Epileptic Drug (AED) Treatment in Children With Refractory SeizuresTerminatedNCT01118455Phase 4
33Pregabalin In Partial Seizures (PREPS): An Open-Label, Multicenter Add On Therapy TrialTerminatedNCT00407797Phase 4
34An Open-Label, Single and Multiple Oral Dose Pharmacokinetic Study of Vigabatrin in Infants With Infantile SpasmsWithdrawnNCT01413711Phase 4
35Addition of Pyridoxine to Prednisolone in Infantile SpasmsUnknown statusNCT01828437Phase 3
36Efficacy Study of Folic Acid Supplementation in Adolescent EpilepticsUnknown statusNCT02318446Phase 3
37Ketamine in Refractory Convulsive Status EpilepticusUnknown statusNCT02431663Phase 3
38Study to Evaluate the Safety and Efficacy of Levetiracetam in Patients Suffering From Idiopathic Generalized Epilepsy With Primary Generalized Tonic-clonic SeizuresCompletedNCT00160550Phase 3
39Long Term Follow up Treatment With Levetiracetam in Subjects of 4 Years and Older With Generalized EpilepsyCompletedNCT00150748Phase 3
40Levetiracetam as add-on Treatment of Myoclonic Jerks in Adolescents + AdultsCompletedNCT00150774Phase 3
41Monotherapy With Levetiracetam in Newly Diagnosed Patients Suffering From EpilepsyCompletedNCT00150735Phase 3
42Clobazam in Patients With Lennox-Gastaut SyndromeCompletedNCT00518713Phase 3
43Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy PatientsCompletedNCT00236886Phase 3
44Brivaracetam as add-on Treatment in Adolescents and Adults Suffering From EpilepsyCompletedNCT00504881Phase 3
45A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent EpilepsyCompletedNCT00231556Phase 3
46Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures.CompletedNCT00319501Phase 3
47Monotherapy With Levetiracetam in Patients Suffering From Epilepsy.CompletedNCT00150813Phase 3
48Monotherapy With Levetiracetam or Carbamazepine in Patients Suffering From Epilepsy.CompletedNCT00150787Phase 3
49Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) SeizuresCompletedNCT00104416Phase 3
50A Double-blind, Placebo-controlled Study of Levetiracetam in Epilepsy Patients With Generalized Tonic-clonic Seizures (Except Partial Seizures Evolving to Secondarily Generalized Seizures)CompletedNCT01228747Phase 3

Search NIH Clinical Center for Idiopathic Generalized Epilepsy


Cochrane evidence based reviews: epilepsy, generalized

Genetic Tests for Idiopathic Generalized Epilepsy

About this section

Genetic tests related to Idiopathic Generalized Epilepsy:

id Genetic test Affiliating Genes
1 Idiopathic Generalized Epilepsy27

Anatomical Context for Idiopathic Generalized Epilepsy

About this section

MalaCards organs/tissues related to Idiopathic Generalized Epilepsy:

36
Brain, Cortex, Temporal lobe, Thalamus, Cingulate cortex, Occipital lobe, Heart

Publications for Idiopathic Generalized Epilepsy

About this section

Articles related to Idiopathic Generalized Epilepsy:

(show top 50)    (show all 306)
idTitleAuthorsYear
1
Dynamic functional network connectivity in idiopathic generalized epilepsy with generalized tonic-clonic seizure. (27726245)
2017
2
Patterns of Gray Matter Abnormalities in Idiopathic Generalized Epilepsy: A Meta-Analysis of Voxel-Based Morphology Studies. (28060866)
2017
3
Effects of Marijuana on Ictal and Interictal EEG Activities in Idiopathic Generalized Epilepsy. (27763968)
2017
4
Perampanel: Another Choice for Patients With Idiopathic Generalized Epilepsy Who Have Tonic-Clonic Seizures. (26900373)
2016
5
A computational biomarker of idiopathic generalized epilepsy from resting state EEG. (27501083)
2016
6
Moral judgment in patients with idiopathic generalized epilepsy. (27567267)
2016
7
Perampanel for the treatment of primary generalized tonic-clonic seizures in idiopathic generalized epilepsy. (27267634)
2016
8
Neocortical gamma oscillations in idiopathic generalized epilepsy. (26996827)
2016
9
Circadian phase typing in idiopathic generalized epilepsy: Dim light melatonin onset and patterns of melatonin secretion-Semicurve findings in adult patients. (27344501)
2016
10
Thalamic hypoperfusion and disrupted cerebral blood flow networks in idiopathic generalized epilepsy: Arterial spin labeling and graph theoretical analysis. (28043066)
2016
11
A diffusional kurtosis imaging study of idiopathic generalized epilepsy with unilateral interictal epileptiform discharges in children. (27269387)
2016
12
Assessment of Time and Frequency Domain Parameters of Heart Rate Variability and Interictal Cardiac Rhythm Abnormalities in Drug-naA^ve Patients with Idiopathic Generalized Epilepsy. (27390676)
2016
13
Patterns of postictal cerebral perfusion in idiopathic generalized epilepsy: a multi-delay multi-parametric arterial spin labelling perfusion MRI study. (27374369)
2016
14
Understanding the burden of idiopathic generalized epilepsy in the United States, Europe, and Brazil: An analysis from the National Health and Wellness Survey. (26773686)
2016
15
Focal interictal epileptiform discharges in idiopathic generalized epilepsy. (26956566)
2016
16
Ethnic variation of genetic (idiopathic) generalized epilepsy in Malaysia. (27912112)
2016
17
Altered Effective Connectivity among Core Neurocognitive Networks in Idiopathic Generalized Epilepsy: An fMRI Evidence. (27656137)
2016
18
Benign adult familial myoclonus epilepsy is a progressive disorder: no longer idiopathic generalized epilepsy. (26907167)
2016
19
Cognitive Profile of Zonisamide and Valproic Acid in the Treatment of Idiopathic Generalized Epilepsy: A Comparative Observational Study. (27086007)
2016
20
No relation between EFHC2 gene polymorphism and Idiopathic generalized epilepsy. (26958022)
2015
21
Motor evoked potential polyphasia: A novel endophenotype of idiopathic generalized epilepsy. (26438619)
2015
22
Investigation of the cingulate cortex in idiopathic generalized epilepsy. (26417846)
2015
23
Perampanel for tonic-clonic seizures in idiopathic generalized epilepsy: A randomized trial. (26296511)
2015
24
Identifying Corticothalamic Network Epicenters in Patients with Idiopathic Generalized Epilepsy. (25907518)
2015
25
Altered functional connectivity among default, attention, and control networks in idiopathic generalized epilepsy. (25935514)
2015
26
Idiopathic generalized epilepsy and hypokalemic periodic paralysis in a family of South Indian descent. (25893123)
2015
27
Motor evoked potential polyphasia: A novel endophenotype of idiopathic generalized epilepsy. (25740859)
2015
28
Selective EEG activation by the Stroop test in idiopathic generalized epilepsy. (25735886)
2015
29
Narcolepsy Type 1 and Idiopathic Generalized Epilepsy: Diagnostic and Therapeutic Challenges in Dual Cases. (26156948)
2015
30
Frequency-Specific Alterations of Local Synchronization in Idiopathic Generalized Epilepsy. (26266394)
2015
31
A prospective study of the modified Atkins diet for adults with idiopathic generalized epilepsy. (26588588)
2015
32
Determination of haptoglobin genotype in an Iranian population with idiopathic generalized epilepsy. (26989737)
2015
33
Choice of Antiepileptic Drugs in Idiopathic Generalized Epilepsy: UAE Experience. (26078878)
2015
34
Association of GABRA6 1519 T>C (rs3219151) and Synapsin II (rs37733634) gene polymorphisms with the development of idiopathic generalized epilepsy. (25088614)
2014
35
MRI segmentation analysis in temporal lobe and idiopathic generalized epilepsy. (24938118)
2014
36
Idiopathic-generalized epilepsy shows profound white matter diffusion-tensor imaging alterations. (25050427)
2014
37
Diffusional kurtosis imaging reveals a distinctive pattern of microstructural alternations in idiopathic generalized epilepsy. (24796428)
2014
38
Microstructural brain abnormalities of children of idiopathic generalized epilepsy with generalized tonic-clonic seizure: A voxel-based diffusional kurtosis imaging study. (24797060)
2014
39
Increased interhemispheric resting-state in idiopathic generalized epilepsy with generalized tonic-clonic seizures: a resting-state fMRI study. (25043752)
2014
40
Valproate treatment normalizes EEG functional connectivity in successfully treated idiopathic generalized epilepsy patients. (25454501)
2014
41
Altered thalamocortical functional connectivity in idiopathic generalized epilepsy. (24650142)
2014
42
Empathy and emotion recognition in patients with idiopathic generalized epilepsy. (25022822)
2014
43
Genetic variants of synaptic vesicle and presynaptic plasma membrane proteins in idiopathic generalized epilepsy. (24164654)
2014
44
EEG activation by neuropsychological tasks in idiopathic generalized epilepsy of adolescence. (25043766)
2014
45
Retraction: microstructural brain abnormalities of children of idiopathic generalized epilepsy with generalized tonic-clonic seizure: a voxel-based diffusional kurtosis imaging study by: Junling Gao, Shi-Ting Feng, Bangxian Wu, Nanjie Gong, Minhua Lu, Po-Man Wu, He Wang, Xiaoming He, and Bingsheng Huang. (25275140)
2014
46
Natural course and predictors of spontaneous seizure remission in idiopathic generalized epilepsy: 7-27 years of follow-up. (24907182)
2014
47
Recognition of facial emotions and identity in patients with mesial temporal lobe and idiopathic generalized epilepsy: An eye-tracking study. (25277844)
2014
48
Investigation of glutamine and GABA levels in patients with idiopathic generalized epilepsy using MEGAPRESS. (24585443)
2014
49
Functional neuroimaging abnormalities in idiopathic generalized epilepsy. (25383319)
2014
50
Exonic microdeletions of the gephyrin gene impair GABAergic synaptic inhibition in patients with idiopathic generalized epilepsy. (24561070)
2014

Variations for Idiopathic Generalized Epilepsy

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Copy number variations for Idiopathic Generalized Epilepsy from CNVD:

6 (show all 43)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1182251144516731146256137Microdeletionsidiopathic generalized epilepsy
28923015144643813146297795Microdeletionsidiopathic generalized epilepsy
390145152020368520795813Microdeletionsidiopathic generalized epilepsy
490146152020368520795813Microdeletionsidiopathic generalized epilepsy
590148152020368520971169Microdeletionsidiopathic generalized epilepsy
69014915202047720629367Microdeletionsidiopathic generalized epilepsy
79015015202047720763914Microdeletionsidiopathic generalized epilepsy
89015115202047720795813Microdeletionsidiopathic generalized epilepsy
99015215202047720850488Microdeletionsidiopathic generalized epilepsy
1090154152022475120799862Microdeletionsidiopathic generalized epilepsy
1190155152022475120852202Microdeletionsidiopathic generalized epilepsy
1290174152030166520795813Microdeletionsidiopathic generalized epilepsy
1390183152031060620850488Microdeletionsidiopathic generalized epilepsy
149029515211063119781829Microdeletionsidiopathic generalized epilepsy
159029615211063120224751Microdeletionsidiopathic generalized epilepsy
1690979152674582130494518Microdeletionsidiopathic generalized epilepsy
1791113152816839730276525Microdeletionsidiopathic generalized epilepsy
1891114152816839730491740Microdeletionsidiopathic generalized epilepsy
1991115152816839730498257Microdeletionsidiopathic generalized epilepsy
2091120152817148330701463Microdeletionsidiopathic generalized epilepsy
2191193152846137530436131Microdeletionsidiopathic generalized epilepsy
2291207152859522230326817Microdeletionsidiopathic generalized epilepsy
2391208152859522230326817Microdeletionsidiopathic generalized epilepsy
249125715287382530215571Microdeletionsidiopathic generalized epilepsy
2591313152900000031400000Microdeletionidiopathic generalized epilepsy
2691314152900000031400000MicrodeletionARHGAP11Bidiopathic generalized epilepsy
2791320152900000031400000MicrodeletionCHRNA7idiopathic generalized epilepsy
2891323152900000031400000MicrodeletionKLF13idiopathic generalized epilepsy
2991326152900000031400000MicrodeletionMTMR10idiopathic generalized epilepsy
3091329152900000031400000MicrodeletionMTMR15idiopathic generalized epilepsy
3191332152900000031400000MicrodeletionOTUD7Aidiopathic generalized epilepsy
3291335152900000031400000MicrodeletionTRPM1idiopathic generalized epilepsy
3397901161469910616308654Microdeletionsidiopathic generalized epilepsy
3497929161474255616285151Microdeletionsidiopathic generalized epilepsy
3597930161474255616285151Microdeletionsidiopathic generalized epilepsy
369794016147853116308654Microdeletionsidiopathic generalized epilepsy
3798024161495620116193208Microdeletionsidiopathic generalized epilepsy
3898029161496121416285151Microdeletionsidiopathic generalized epilepsy
3998092161518630718192575Microdeletionsidiopathic generalized epilepsy
4098108161538633818291982Microdeletionsidiopathic generalized epilepsy
4198278161676791478531Microdeletionsidiopathic generalized epilepsy
42100033162955925130101408Microdeletionsidiopathic generalized epilepsy
43161088221725833919786713Microdeletionsidiopathic generalized epilepsy

Expression for genes affiliated with Idiopathic Generalized Epilepsy

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Search GEO for disease gene expression data for Idiopathic Generalized Epilepsy.

Pathways for genes affiliated with Idiopathic Generalized Epilepsy

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Pathways related to Idiopathic Generalized Epilepsy according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.7GABRA1, GABRG2
2
Show member pathways
9.5KCNJ10, KCNQ2, KCNQ3
3
Show member pathways
9.5CACNB4, SCN1A, SCN1B
49.4KCNQ2, KCNQ3, SCN1A, SCN1B
5
Show member pathways
9.4KCNQ2, KCNQ3, SCN1A, SCN1B
69.2CACNA1H, CACNB4, KCNQ2, KCNQ3
79.1CACNB4, KCNJ10, KCNQ2, KCNQ3
8
Show member pathways
9.1CACNA1H, CHRNA4, KCNQ2, KCNQ3, SCN1A
99.1KCNQ2, SCN1A, SCN1B, SLC12A5
10
Show member pathways
8.9GABRA1, GABRB3, GABRG2
11
Show member pathways
8.5GABRA1, GABRB3, GABRG2, KCNJ10
12
Show member pathways
8.4CLCN2, GABRA1, GABRB3, GABRG2
138.3GABRA1, GABRB3, GABRD, GABRG2
14
Show member pathways
8.3GABRA1, GABRB3, GABRD, GABRG2
158.0CHRNA4, GABRA1, GABRB3, GABRD, GABRG2
16
Show member pathways
7.8GABRA1, GABRB3, GABRD, GABRG2, SLC12A5
17
Show member pathways
7.6CACNA1H, CACNB4, GABRA1, GABRB3, GABRD, GABRG2
18
Show member pathways
7.2CACNB4, CHRNA4, GABRA1, GABRB3, GABRG2, KCNJ10

GO Terms for genes affiliated with Idiopathic Generalized Epilepsy

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Cellular components related to Idiopathic Generalized Epilepsy according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1sodium channel complexGO:003470610.6SCN1A, SCN1B
2axon initial segmentGO:004319410.6KCNQ2, KCNQ3, SCN1A
3node of RanvierGO:003326810.2KCNQ2, KCNQ3, SCN1A, SCN1B
4voltage-gated calcium channel complexGO:000589110.1CACNA1H, CACNB4
5neuronal cell bodyGO:004302510.0CHRNA4, EFHC1, SCN1A, SLC12A5
6voltage-gated sodium channel complexGO:00015189.9SCN1A, SCN1B
7cytoplasmic vesicle membraneGO:00306599.8GABRA1, GABRB3, GABRG2
8GABA-A receptor complexGO:19027119.1GABRA1, GABRB3, GABRD, GABRG2
9cell junctionGO:00300548.8CHRNA4, GABRA1, GABRB3, GABRD, GABRG2
10chloride channel complexGO:00347078.7CLCN2, GABRA1, GABRB3, GABRD, GABRG2
11postsynaptic membraneGO:00452118.6CHRNA4, GABRA1, GABRB3, GABRD, GABRG2
12synapseGO:00452028.4CHRNA4, GABRA1, GABRB3, GABRD, GABRG2
13integral component of plasma membraneGO:00058878.2GABRA1, GABRB3, GABRD, GABRG2, KCNJ10, SLC12A5
14integral component of membraneGO:00160216.1CACNA1H, CHRNA4, CLCN2, GABRA1, GABRB3, GABRD
15membraneGO:00160206.0CACNA1H, CHRNA4, CLCN2, GABRA1, GABRB3, GABRD
16plasma membraneGO:00058865.5CACNA1H, CACNB4, CHRNA4, CLCN2, GABRA1, GABRB3

Biological processes related to Idiopathic Generalized Epilepsy according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1membrane depolarization during action potentialGO:008601010.8CACNA1H, SCN1A
2neuronal action potentialGO:001922810.8CACNA1H, SCN1A
3cardiac muscle cell action potential involved in contractionGO:008600210.7SCN1A, SCN1B
4neuronal action potential propagationGO:001922710.7SCN1A, SCN1B
5adult walking behaviorGO:000762810.7KCNJ10, SCN1A
6synaptic transmission, GABAergicGO:005193210.5GABRA1, GABRG2
7sodium ion transmembrane transportGO:003572510.4CACNA1H, SCN1A, SCN1B
8calcium ion transportGO:000681610.3CACNA1H, CACNB4, CHRNA4
9membrane depolarizationGO:005189910.2CACNB4, CHRNA4, SCN1B
10inhibitory postsynaptic potentialGO:006008010.1CHRNA4, GABRB3
11regulation of membrane potentialGO:004239110.0CACNA1H, CHRNA4, KCNJ10, SCN1A
12potassium ion transmembrane transportGO:00718059.8KCNJ10, KCNQ2, KCNQ3, SLC12A5
13potassium ion transportGO:00068139.8KCNJ10, KCNQ2, KCNQ3, SLC12A5
14cellular response to histamineGO:00714209.7GABRA1, GABRB3, GABRG2
15gamma-aminobutyric acid signaling pathwayGO:00072149.7GABRA1, GABRB3, GABRG2
16regulation of postsynaptic membrane potentialGO:00600789.6CACNA1H, CHRNA4, GABRA1, SCN1A, SCN1B
17transmembrane transportGO:00550859.2CACNA1H, CLCN2, KCNQ2, KCNQ3, SCN1A, SLC12A5
18regulation of ion transmembrane transportGO:00347658.6CACNA1H, CACNB4, CLCN2, KCNJ10, KCNQ2, KCNQ3
19chemical synaptic transmissionGO:00072688.3CACNB4, CHRNA4, GABRD, GABRG2, KCNQ2, KCNQ3
20chloride transmembrane transportGO:19024768.1CLCN2, GABRA1, GABRB3, GABRD, GABRG2, SLC12A5
21chloride transportGO:00068218.1CLCN2, GABRA1, GABRB3, GABRD, GABRG2, SLC12A5
22ion transmembrane transportGO:00342207.5CACNA1H, CHRNA4, CLCN2, GABRA1, GABRB3, GABRD
23ion transportGO:00068115.6CACNA1H, CACNB4, CHRNA4, CLCN2, GABRA1, GABRB3
24transportGO:00068104.8CACNA1H, CACNB4, CHRNA4, CLCN2, GABRA1, GABRB3

Molecular functions related to Idiopathic Generalized Epilepsy according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1sodium channel activityGO:000527210.5SCN1A, SCN1B
2potassium channel activityGO:000526710.1KCNJ10, KCNQ2, KCNQ3
3GABA-gated chloride ion channel activityGO:00228519.8GABRA1, GABRB3
4voltage-gated sodium channel activityGO:00052489.6CACNA1H, SCN1A, SCN1B
5ion channel activityGO:00052169.2CHRNA4, GABRA1, GABRB3, SCN1A
6GABA-A receptor activityGO:00048908.9GABRA1, GABRB3, GABRD, GABRG2
7voltage-gated ion channel activityGO:00052448.6CACNA1H, CLCN2, KCNJ10, KCNQ2, KCNQ3, SCN1A
8extracellular ligand-gated ion channel activityGO:00052308.6CHRNA4, GABRA1, GABRB3, GABRD, GABRG2
9chloride channel activityGO:00052548.5CLCN2, GABRA1, GABRB3, GABRD, GABRG2

Sources for Idiopathic Generalized Epilepsy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet