MCID: IDP011
MIFTS: 39

Idiopathic Interstitial Pneumonia malady

Aliases & Classifications for Idiopathic Interstitial Pneumonia

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Idiopathic Interstitial Pneumonia, Aliases & Descriptions:

Name: Idiopathic Interstitial Pneumonia 9
Idiopathic Interstitial Pneumonia, Not Otherwise Specified 60
Diffuse Idiopathic Pulmonary Fibrosis 9
 
Idiopathic Interstitial Pneumonias 60
Idiopathic Fibrosing Alveolitis 9
Hamman-Rich Syndrome 60


Summaries for Idiopathic Interstitial Pneumonia

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Wikipedia:63 Idiopathic interstitial pneumonia (IIP), or noninfectious pneumonia are a class of diffuse lung... more...

MalaCards based summary: Idiopathic Interstitial Pneumonia, also known as idiopathic interstitial pneumonia, not otherwise specified, is related to pneumonia and respiratory failure. An important gene associated with Idiopathic Interstitial Pneumonia is CMA1 (chymase 1, mast cell), and among its related pathways is SIDS Susceptibility Pathways. The compounds scca1 and budesonide have been mentioned in the context of this disorder. Affiliated tissues include the lung parenchyma of unknown cause, lung and testes, and related mouse phenotypes are hematopoietic system and respiratory system.

Disease Ontology:9 A pneumonia located in the lung parenchyma of unknown cause.

Related Diseases for Idiopathic Interstitial Pneumonia

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Diseases related to Idiopathic Interstitial Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.7SFTPD, IL13
2respiratory failure30.5IL13, CMA1, SFTPD
3dermatomyositis30.4SFTPD, CCR7
4pulmonary fibrosis, idiopathic30.1SFTPD, CCR7, IL13
5influenza30.0CCR7, SFTPD
6nonspecific interstitial pneumonia10.6
7connective tissue disease10.5
8lung cancer10.4
9desquamative interstitial pneumonia10.4
10anorchia10.4
11keratoconjunctivitis10.4IL13
12pulmonary hypertension10.3
13interstitial lung disease10.3
14vascular disease10.3
15vernal keratoconjunctivitis10.2IL13, CMA1
16mastocytosis10.2CMA1, IL13
17rhinitis10.2IL13, CMA1
18atopy10.2IL13, CMA1
19pulmonary function10.2
20psoriatic arthritis10.2
21arthritis10.2
22acute interstitial pneumonia10.2
23cryptogenic organizing pneumonia10.2
24lymphoid interstitial pneumonia10.2
25bird fancier's lung10.2
26myopathy10.2
27airway-centered interstitial fibrosis10.2
28antisynthetase syndrome10.2
29blindness10.2
30respiratory bronchiolitis - interstitial lung disease10.2
31dermatitis10.2IL13, CMA1
32pulmonary eosinophilia10.2SFTPD, IL13
33atopic dermatitis10.1IL13, CMA1
34sarcoidosis 110.1IL13, SFTPD
35pulmonary disease, chronic obstructive10.1SFTPD, IL13
36polymyositis10.1CCR7, SFTPD
37tetanus10.1IL13, CCR7
38systemic scleroderma10.1SFTPD, IL13
39cork-handlers' disease10.0IL13, SFTPD
40skin disease10.0IL13, SFTPD
41allergic asthma10.0SFTPD, CMA1, IL13
42hiv-110.0CCR7, SFTPD
43psoriasis9.9IL13, CCR7, CMA1
44tongue squamous cell carcinoma9.9CCR7, ASCL1, CMA1
45rheumatoid arthritis9.8SFTPD, CCR7, IL13
46pulmonary fibrosis9.7SFTPD, CMA1, CCR7, IL13
47asthma9.7IL13, CCR7, CMA1, SFTPD

Graphical network of the top 20 diseases related to Idiopathic Interstitial Pneumonia:



Diseases related to idiopathic interstitial pneumonia

Symptoms for Idiopathic Interstitial Pneumonia

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Drugs & Therapeutics for Idiopathic Interstitial Pneumonia

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Drug clinical trials:

Search ClinicalTrials for Idiopathic Interstitial Pneumonia

Search NIH Clinical Center for Idiopathic Interstitial Pneumonia

Genetic Tests for Idiopathic Interstitial Pneumonia

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Anatomical Context for Idiopathic Interstitial Pneumonia

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MalaCards organs/tissues related to Idiopathic Interstitial Pneumonia:

31
Lung, Testes, Bone marrow, Bone, Colon

FMA organs/tissues related to Idiopathic Interstitial Pneumonia:

14
The lung parenchyma of unknown cause

Animal Models for Idiopathic Interstitial Pneumonia or affiliated genes

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MGI Mouse Phenotypes related to Idiopathic Interstitial Pneumonia:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.3SFTPD, CMA1, CCR7, IL13
2MP:00053888.2GREM1, IL13, ASCL1, SFTPD
3MP:00053878.1SFTPD, CMA1, CCR7, IL13
4MP:00053848.1GREM1, IL13, CCR7, ASCL1

Publications for Idiopathic Interstitial Pneumonia

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Articles related to Idiopathic Interstitial Pneumonia:

(show top 50)    (show all 111)
idTitleAuthorsYear
1
Newly Detected Pulmonary Nontuberculous Mycobacterial Infection and Peripheral Lung Cancers in Patients During Follow-Up of Idiopathic Interstitial Pneumonia: Comparison of CT Findings. (25837763)
2015
2
Bosentan in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia. (24937643)
2014
3
Expression of toll-like receptor 2 and 4 is increased in the respiratory epithelial cells of chronic idiopathic interstitial pneumonia patients. (24613046)
2014
4
Quadriceps strength and endurance in fibrotic idiopathic interstitial pneumonia. (24033388)
2014
5
Limitations to the 6-minute walk test in dermatomyositis with interstitial lung disease in comparison with idiopathic interstitial pneumonia. (23400027)
2013
6
Immunohistochemical detection of virus through its nuclear cytopathic effect in idiopathic interstitial pneumonia other than acute exacerbation. (24270907)
2013
7
Clinical significance of serum autoantibodies in idiopathic interstitial pneumonia. (23678265)
2013
8
MMP-7 and fcDNA Serum Levels in Early NSCLC and Idiopathic Interstitial Pneumonia: Preliminary Study. (24336111)
2013
9
Chemotherapy for non-small cell lung cancer complicated by idiopathic interstitial pneumonia. (23741246)
2012
10
Pulmonary function vascular index predicts prognosis in idiopathic interstitial pneumonia. (22212399)
2012
11
Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patients. (23106582)
2012
12
Prognostic value of immunohistochemical surfactant protein A expression in regenerative/hyperplastic alveolar epithelial cells in idiopathic interstitial pneumonias. (21435274)
2011
13
Postoperative respiratory failure caused by acute exacerbation of idiopathic interstitial pneumonia. (21487668)
2011
14
Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias. (21177844)
2011
15
Metagenomic analysis of bronchoalveolar lavage samples from patients with idiopathic interstitial pneumonia and its antagonic relation with Pneumocystis jirovecii colonization. (20382190)
2010
16
Epithelial apoptosis as a clinical marker in idiopathic interstitial pneumonia. (20542676)
2010
17
Predictors of survival in idiopathic interstitial pneumonia. (20707290)
2010
18
Small airway remodeling in idiopathic interstitial pneumonias: a pathological study. (19690403)
2010
19
Interleukin-13 and its receptors in idiopathic interstitial pneumonia: clinical implications for lung function. (19654941)
2009
20
Serum albumin concentration and waiting list mortality in idiopathic interstitial pneumonia. (19017875)
2009
21
TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation. (18633634)
2008
22
Gremlin localization and expression levels partially differentiate idiopathic interstitial pneumonia severity and subtype. (18072275)
2008
23
Parenchymal and vascular interactions in the pathogenesis of nonspecific interstitial pneumonia in systemic sclerosis and idiopathic interstitial pneumonia. (18073456)
2008
24
Surfactant protein C mutations in sporadic forms of idiopathic interstitial pneumonias. (17005585)
2007
25
Enhanced mast cell chymase expression in human idiopathic interstitial pneumonia. (17334631)
2007
26
Increased pulmonary neurotrophin protein expression in idiopathic interstitial pneumonias. (18069415)
2007
27
Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography. (16272854)
2005
28
Nonhomogeneous density of CD34 and VCAM-1 alveolar capillaries in major types of idiopathic interstitial pneumonia. (16389728)
2005
29
Semiquantitative 67Ga scintigraphy as an indicator of response to and prognosis after corticosteroid treatment in idiopathic interstitial pneumonia. (16157523)
2005
30
Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia. (15161635)
2004
31
Angiogenic cytokines in patients with idiopathic interstitial pneumonia. (15223865)
2004
32
A case with acute quadriplegic myopathy following intensive care for idiopathic interstitial pneumonia. (15055401)
2003
33
Idiopathic interstitial pneumonia following stem cell transplantation. (12868990)
2003
34
Prognostic implications of physiologic and radiographic changes in idiopathic interstitial pneumonia. (12773329)
2003
35
Fibrotic idiopathic interstitial pneumonia: the prognostic value of longitudinal functional trends. (12791580)
2003
36
Predicting survival of lung transplantation candidates with idiopathic interstitial pneumonia: does PaO(2) predict survival? (12226013)
2002
37
Steroid treatment based on the findings of transbronchial biopsy in idiopathic interstitial pneumonia. (12449176)
2002
38
Modulation of pulmonary neuroendocrine cells in idiopathic interstitial pneumonia. (12371140)
2002
39
Centrilobular fibrosis: a novel histological pattern of idiopathic interstitial pneumonia. (12440779)
2002
40
The clinical significance of histopathologic subgroups in idiopathic interstitial pneumonia: is surgical lung biopsy essential? (16088685)
2001
41
Nonspecific interstitial pneumonia and the other idiopathic interstitial pneumonias: classification and diagnostic criteria. (10632482)
2000
42
Clinical evaluation of idiopathic interstitial pneumonia and interstitial pneumonia associated with collagen vascular disease using logistic regression analysis. (10772122)
2000
43
Surfactant protein A in bronchoalveolar lavage fluid from patients with idiopathic interstitial pneumonia]. (9022314)
1996
44
Lactic dehydrogenase-immunoglobulin G kappa complex in a patient with idiopathic interstitial pneumonia. (8797059)
1996
45
Role of alveolar macrophages in the pathogenesis of idiopathic interstitial pneumonia]. (9216211)
1996
46
Factors affecting prognosis of idiopathic interstitial pneumonia. (8701780)
1996
47
Can interstitial pneumonia as the sole presentation of collagen vascular diseases be differentiated from idiopathic interstitial pneumonia? (8560090)
1995
48
Three cases of idiopathic interstitial pneumonia with bullae seen in schoolteachers. (7485195)
1995
49
A case of severe IgA nephropathy associated with psoriatic arthritis and idiopathic interstitial pneumonia. (8237372)
1993
50
Four cases of lung cancer associated with idiopathic interstitial pneumonia. (2167507)
1990

Variations for Idiopathic Interstitial Pneumonia

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Expression for genes affiliated with Idiopathic Interstitial Pneumonia

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Search GEO for disease gene expression data for Idiopathic Interstitial Pneumonia.

Pathways for genes affiliated with Idiopathic Interstitial Pneumonia

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Pathways related to Idiopathic Interstitial Pneumonia according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5IL13, ASCL1

Compounds for genes affiliated with Idiopathic Interstitial Pneumonia

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Sources:
43Novoseek, 49PharmGKB, 12DrugBank, 24HMDB, 28IUPHAR
See all sources

Compounds related to Idiopathic Interstitial Pneumonia according to GeneCards Suite gene sharing:

(show all 17)
idCompoundScoreTop Affiliating Genes
1scca1439.8IL13, CMA1
2budesonide43 49 1211.7IL13, SFTPD
3nickel43 2410.6IL13, CCR7
4tarc439.6CCR7, IL13
5ccl343 2810.6IL13, CCR7
6ccl443 2810.5CCR7, IL13
7prednisolone43 28 1211.5IL13, SFTPD
8inositol439.4IL13, SFTPD
9allergens439.3IL13, CMA1, SFTPD
10tacrolimus43 49 1211.3IL13, CCR7
11mannose439.3SFTPD, IL13
12histamine43 28 2411.3SFTPD, CMA1, IL13
13endotoxin439.1IL13, SFTPD
14phosphatidylinositol438.9SFTPD, CCR7, IL13
15dexamethasone43 49 28 1211.8GREM1, IL13, SFTPD
16cysteine438.5SFTPD, CMA1, IL13, GREM1
17tyrosine438.2GREM1, IL13, CCR7, ASCL1

GO Terms for genes affiliated with Idiopathic Interstitial Pneumonia

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Cellular components related to Idiopathic Interstitial Pneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.3IL13, CCR7
2extracellular spaceGO:00056158.3GREM1, IL13, SFTPD

Biological processes related to Idiopathic Interstitial Pneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to lipopolysaccharideGO:00324969.3IL13, CCR7
2positive regulation of angiogenesisGO:00457668.9GREM1, CMA1

Molecular functions related to Idiopathic Interstitial Pneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051259.1GREM1, IL13

Products for genes affiliated with Idiopathic Interstitial Pneumonia

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Sources for Idiopathic Interstitial Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet