MCID: IDP002
MIFTS: 43

Idiopathic Juvenile Osteoporosis malady

Rare diseases, Bone diseases, Fetal diseases categories

Aliases & Classifications for Idiopathic Juvenile Osteoporosis

About this section
Sources:
10Disease Ontology, 45NIH Rare Diseases, 47Novoseek, 12DISEASES, 51Orphanet, 65UMLS, 59SNOMED-CT, 29ICD9CM, 28ICD10 via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Idiopathic Juvenile Osteoporosis:

Name: Idiopathic Juvenile Osteoporosis 10 45 47 12 51
Juvenile Osteoporosis 10 45 51 65
Idiopathic Osteoporosis 10 47 65
 
Ijo 45 51
Osteoporosis, Juvenile 45


Classifications:



Characteristics (Orphanet epidemiological data):

51
idiopathic juvenile osteoporosis:
Inheritance: Multigenic/multifactorial,Not applicable; Age of onset: Childhood


External Ids:

Disease Ontology10 DOID:12559
ICD9CM29 733.02
Orphanet51 85193
SNOMED-CT59 3345002
ICD10 via Orphanet28 M81.5
ICD1027 M80.5, M81.5

Summaries for Idiopathic Juvenile Osteoporosis

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NIH Rare Diseases:45 Juvenile osteoporosis is a condition of bone demineralization characterized by pain in the back and extremities, multiple fractures, difficulty walking, and evidence of osteoporosis. symptoms typically develop just before puberty. osteoporosis is rare in children and adolescents. when it does occur, it is usually caused by an underlying medical disorder or by medications used to treat the disorder. this is called secondary osteoporosis. sometimes, however, there is no identifiable cause of osteoporosis in a child. this is known as idiopathic osteoporosis. there is no established medical or surgical therapy for juvenile osteoporosis. in some cases, treatment is not necessary, as the condition resolves spontaneously. early diagnosis may allow for preventive steps, including physical therapy, avoidance of weight-bearing activities, use of crutches and other supportive care. a well-balanced diet rich in calcium and vitamin d is also important. in severe, long-lasting cases, medications such as bisphosphonates may be used. in most cases, complete recovery of bone occurs.  last updated: 5/30/2012

MalaCards based summary: Idiopathic Juvenile Osteoporosis, also known as juvenile osteoporosis, is related to bone structure disease and osteoporosis, and has symptoms including bone pain, recurrent fractures and reduced bone mineral density. An important gene associated with Idiopathic Juvenile Osteoporosis is WNT1 (Wingless-Type MMTV Integration Site Family, Member 1), and among its related pathways are Regulation of FZD by ubiquitination and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. Affiliated tissues include bone, testes and skin, and related mouse phenotypes are craniofacial and hearing/vestibular/ear.

Disease Ontology:10 An osteoporosis with no known cause that is characterized by pain in the back and extremities, walking difficulties, multiple fractures, and radiological evidence of osteoporosis.

Related Diseases for Idiopathic Juvenile Osteoporosis

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Diseases related to Idiopathic Juvenile Osteoporosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1bone structure disease30.1BGLAP, CALCA, IGF1, LRP5
2osteoporosis29.7BGLAP, CALCA, COL1A1, DKK1, GC, IGF1
3osteogenesis imperfecta10.3
4juvenile primary osteoporosis10.3
5insulin-like growth factor i10.3
6waldeyer's ring cancer10.3BGLAP, CALCA
7bone inflammation disease10.2BGLAP, CALCA
8mucolipidosis10.2BGLAP, CALCA
9nodular goiter10.2BGLAP, CALCA
10ureter inverted papilloma10.2CALCA, LRP5
11brain glioblastoma multiforme10.2BGLAP, LRP5
12marcus gunn phenomenon10.2BGLAP, CALCA
13prostatic cyst10.2BGLAP, CALCA
14anemia, sideroblastic, pyridoxine-refractory, autosomal recessive10.2
15arthritis10.2
16bone fracture10.2
17juvenile rheumatoid arthritis10.2
18secondary syphilis10.2
19bone remodeling disease10.2
20calcium metabolism disease10.2
21connective tissue disease10.2
22ehlers-danlos syndrome10.2
23mineral metabolism disease10.2
24scoliosis10.2
25marchiafava bignami disease10.2
26back pain10.2
27hypoinsulinemic hypoglycemia with hemihypertrophy10.2BGLAP, LRP5
28candidiasis10.2BGLAP, CALCA
29spastic cerebral palsy10.2LRP5, WNT3A
30parietal lobe neoplasm10.1BGLAP, CALCA
31ichthyosiform erythroderma, corneal involvement, deafness10.1LRP5, WNT3A
32caffey disease10.1BGLAP, COL1A1
33clear cell adenoma10.1CALCA, IGF1
34ichthyosis with confetti10.1COL1A1, LRP5
35bone resorption disease10.1BGLAP, CALCA, LRP5
36osteogenesis imperfecta, type iv10.1COL1A1, WNT1
37hereditary elliptocytosis10.1BGLAP, CALCA
38neuroectodermal tumor10.1BGLAP, CALCA
39slow-channel congenital myasthenic syndrome10.1IGF1, IGFBP3
40secondary glomerular disease10.0IGF1, IGFBP3
41osteogenesis imperfecta, type iii10.0BGLAP, COL1A1, WNT1
42breast large cell neuroendocrine carcinoma10.0IGF1, IGFBP3
43shigellosis10.0IGF1, IGFBP3
44progeria-associated arthropathy10.0IGF1, IGFBP3
45anterior cruciate ligament tears10.0BGLAP, COL1A1, LRP5
46glomerulosclerosis, focal segmental, 110.0IGF1, IGFBP3
47hypersensitivity reaction type ii disease10.0IGF1, IGFBP3
48bone mineral density, low10.0
49bone development disease10.0
50vitamin metabolic disorder10.0

Graphical network of the top 20 diseases related to Idiopathic Juvenile Osteoporosis:



Diseases related to idiopathic juvenile osteoporosis

Symptoms for Idiopathic Juvenile Osteoporosis

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Symptoms:

 51
  • osteoporosis/osteopenia/demineralisation/osteomalacia/rickets
  • mutiple fractures/bone fragility
  • bone pain
  • motor deficit/trouble
  • abnormal gait
  • kyphosis

HPO human phenotypes related to Idiopathic Juvenile Osteoporosis:

(show all 8)
id Description Frequency HPO Source Accession
1 bone pain hallmark (90%) HP:0002653
2 recurrent fractures hallmark (90%) HP:0002757
3 reduced bone mineral density hallmark (90%) HP:0004349
4 gait disturbance typical (50%) HP:0001288
5 kyphosis occasional (7.5%) HP:0002808
6 autosomal recessive inheritance HP:0000007
7 osteoporosis HP:0000939
8 low serum calcitriol (1,25-dihydroxycholecalciferol) HP:0012052

Drugs & Therapeutics for Idiopathic Juvenile Osteoporosis

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Drugs for Idiopathic Juvenile Osteoporosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AlendronateapprovedPhase 4, Phase 2, Phase 3153121268-17-5, 66376-36-12088
Synonyms:
(4-Amino-1-hydroxybutylidene)bisphosphonic acid
(4-Amino-1-hydroxybutylidene)diphosphonic acid
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
(4-amino-1-hydroxybutane-1,1-diyl)bis(phosphonic acid)
121268-17-5 (mono-hydrochloride salt, trihydrate)
1yhm
4-Amino-1-hydroxybutane-1,1-diphosphonate
4-Amino-1-hydroxybutane-1,1-diphosphonic Acid
4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
4-Amino-1-hydroxybutylidene-1,1-bisphosphonate
66376-36-1
AC1L1CW3
AKOS001015793
ALENDRONATE SODIUM
ALENDRONIC ACID
Acide Alendronique
Acide Alendronique [INN-French]
Acide alendronique
Acide alendronique [INN-French]
Acido Alendronico
Acido Alendronico [INN-Spanish]
Acido alendronico
Acido alendronico [INN-Spanish]
Acidum Alendronicum
Acidum Alendronicum [INN-Latin]
Acidum alendronicum
Acidum alendronicum [INN-Latin]
Adronat
Alendronate
Alendronate Sodium
 
Alendronate sodium hydrate
Alendronic acid
Alendronic acid (INN)
Alendronic acid [INN:BAN]
Alendros
Arendal
BIDD:GT0180
Binosto
C07752
CHEBI:2567
CHEMBL870
CID2088
D07119
DB00630
Fosamax
Fosamax Plus D
HSCI1_000337
LS-106421
MK 217
MK-217
MolPort-000-421-410
NCGC00096054-01
NCGC00096054-03
NCGC00096054-04
Onclast
Oprea1_422906
Phosphonic acid, (4-amino-1-hydroxybutylidene)bis
SPECTRUM1505166
ST50036159
UNII-X1J18R4W8P
alendronate
bisphosphonate, 65
2
PamidronateapprovedPhase 44240391-99-94674
Synonyms:
(3-AMINO-1-HYDROXY-1-PHOSPHONO-PROPYL)PHOSPHONIC ACID
(3-Amino-1-hydroxypropylidene)bisphosphonic acid
(3-Amino-1-hydroxypropylidene)diphosphonic acid
(3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid
(3-amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid)
(3-amino-1-hydroxypropylidene)-1,1-biphosphonate
(3-amino-1-hydroxypropylidene)-1,1-bisphosphonate
1-hydroxy-3-aminopropane-1,1-diphosphonic acid
3-Amino-1-hydroxypropylidene-1,1-diphosphonate
40391-99-9
57248-88-1
57248-88-1 (di-hydrochloride salt)
AC1L1IP4
AHPrBP
AKOS003599275
APD
Acide pamidronique
Acide pamidronique [INN-French]
Acido pamidronico
Acido pamidronico [INN-Spanish]
Acidum pamidronicum
Acidum pamidronicum [INN-Latin]
Amidronate
Aminomux
Aredia
BIDD:GT0538
Bisphosphonate 6
C019248
C07395
C3H11NO7P2
 
CHEMBL834
CID4674
ChemDiv1_025240
D07281
DB00282
EINECS 254-905-2
HMS2090C13
HMS658L06
HSCI1_000312
I14-2407
LS-174826
MolPort-002-131-054
NCGC00159433-02
NCGC00159433-03
Novartis brand of pamidronate disodium salt
PAMIDRONATE DISODIUM
PAMIDRONIC ACID
Pamidronate Disodium
Pamidronic acid
Pamidronic acid (INN)
Pamidronic acid [INN:BAN]
Ribodroat
Ribodroat (TN)
STOCK1N-12562
UNII-OYY3447OMC
amino-1-hydroxypropane-1,1-diphosphonate
aminohydroxypropylidene diphosphonate
aminopropanehydroxydiphosphonate
pamidronate
pamidronate calcium
pamidronate monosodium
3DiphosphonatesPhase 4, Phase 2369
4
NaproxenapprovedPhase 323322204-53-11302, 156391
Synonyms:
(+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(+)-(S)-Naproxen
(+)-2-(6-Methoxy-2-naphthyl)propionic acid
(+)-2-(Methoxy-2-naphthyl)-propionic acid
(+)-2-(Methoxy-2-naphthyl)-propionsaeure
(+)-2-(Methoxy-2-naphthyl)-propionsaeure [German]
(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(+)-Naproxen
(+)NAPROXEN
(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
(S)-()-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-()-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-(+)-Naproxen
(S)-2-(6-Methoxy-2-naphthyl)propanoic acid
(S)-2-(6-Methoxy-2-naphthyl)propionic acid
(S)-6-Methoxy-.alpha.-methyl-2-naphthaleneacetic acid
(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid
(S)-Naproxen
2-(6-Methoxy-2-naphthyl)propionic acid
2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, (+)- (8CI)
22204-53-1
284785_ALDRICH
46482_FLUKA
46482_RIEDEL
65126_FLUKA
AC-1363
AC1L4G3X
AC1Q4ET9
AC1Q4F4H
AC1Q4F4I
ARONIS24306
Acusprain
Aleve
Anaprox
Anax
Anexopen
Apo-Napro-NA
Apo-Naproxen
Apronax
Artagen
Arthrisil
Artrixen
Artroxen
Atiflan
Axer
BIDD:GT0062
BRD-K59197931-001-02-9
BRD-K59197931-236-09-6
BSPBio_002067
Bipronyl
Bonyl
CAS-22204-53-1
CCRIS 5265
CG 3117
CHEBI:7476
CHEMBL154
CID156391
Calosen
Clinosyn
Congex
D-Naproxen
DB08298
DL Naproxen
DL-Naproxen
Danaprox
Daprox
Diocodal
DivK1c_000242
Duk
Dysmenalgit
Dysmenalgit N
EINECS 244-838-7
Ec-Naprosyn
Ec-naprosyn
Equiproxen
Equiproxen (Veterinary)
FT-0082415
Flanax Forte
Flexen
Flexipen
Floginax
Fuxen
Genoxen
HMS1920P13
HMS2089N21
HMS2091H12
HMS500M04
HSDB 3369
Headlon
IDI1_000242
InChI=1/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
KBio1_000242
KBio2_001457
KBio2_004025
KBio2_006593
KBio3_001567
KBioGR_000597
KBioSS_001457
LS-124738
Laraflex
Lefaine
Leniartil
 
Lopac0_000792
M1021
Methoxypropiocin
MolPort-000-145-960
N8280_SIAL
NAPROXEN
NCGC00016759-01
NCGC00021127-01
NCGC00161591-01
NINDS_000242
NPS
Nafasol
Naixan
Nalyxan
Napflam
Napmel
Naposin
Napratec
Naprelan
Napren
Napren E
Naprius
Naprolag
Naprontag
Naprosin
Naprosyn
Naprosyn LLE
Naprosyn LLE Forte
Naprosyne
Naproxen
Naproxen Kit
Naproxen Sodium
Naproxen [USAN:BAN:INN:JAN]
Naproxen delayed release
Naproxen sodium
Naproxene
Naproxene [INN-French]
Naproxeno
Naproxeno [INN-Spanish]
Naproxenum
Naproxenum [INN-Latin]
Naproxi 250
Naproxi 500
Naproxène
Napxen
Narma
Narocin
Naxen
Naxen F
Naxopren
Naxyn
Naxyn 250
Naxyn 500
Noflam
Novonaprox
Nycopren
Opipramol
Patxen
Prafena
Prestwick0_000791
Prestwick1_000791
Prestwick2_000791
Prestwick_349
Prexan
Priaxen
Pronaxen
Proxen LE
Proxen LLE
RS 3540
RS-3540
Rahsen
Reuxen
Rheumaflex
Roxen
SPBio_000966
SPBio_002861
SPECTRUM1500425
SR-01000075977-3
STOCK1N-50633
Saritilron
Sinartrin
Sinton
Soproxen
Spectrum2_001043
Spectrum3_000514
Spectrum4_000069
Spectrum5_001327
Spectrum_000977
Sutolin
Sutony
TL8003659
Tohexen
Traumox
U-Ritis
UNII-57Y76R9ATQ
UPCMLD-DP001
UPCMLD-DP001:001
Velsay
Veradol
Vinsen
Xenar
d-2-(6'-Methoxy-2'-naphthyl)-propionsaeure
d-2-(6'-Methoxy-2'-naphthyl)-propionsaeure [German]
d-2-(6-Methoxy-2-naphthyl)propionic acid
d-Naproxen
5
MeloxicamapprovedPhase 37171125-38-75281106, 54677470
Synonyms:
(3E)-3-[hydroxy-[(5-methyl-1,3-thiazol-2-yl)amino]methylidene]-2-methyl-1,1-dioxo-1
133687-22-6
2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methylthiazolyl)-, 1,1-dioxide
4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
4-Hydroxy-2-methyl-N-(5-methyl-2-thiazoyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
4-hydroxy-2-mehtyl-N-(5-mehtyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
71125-38-7
AC-1325
AC1NQY12
AC1Q3XZW
AKOS000279442
Abbott brand of meloxicam
Almirall brand of meloxicam
Apo-meloxicam
Bio-0826
Boehringer Ingelheim brand of meloxicam
C065757
C08169
C14H13N3O4S2
CCRIS 9139
CHEMBL599
CID5281106
Co Meloxicam
D00969
DB00814
Dom-meloxicam
Europharma brand of meloxicam
FT-0082769
Gen-meloxicam
HMS1922D19
HMS2089B18
I06-0490
LS-40538
M1959
Masflex
 
Meloxicam
Meloxicam (JAN/USAN/INN)
Meloxicam [USAN:BAN:INN]
Meloxicamum
Meloxicamum [Latin]
Meloxicamum [latin]
Meloxivet
Metacam
Mobec
Mobic
Mobic (TN)
Mobic, Metacam, Parocin, Meloxicam
Mobicox
MolPort-002-885-839
Movalis
Movatec
Movicox
Méloxicam
Novo-meloxicam
PHL-meloxicam
PMS-meloxicam
Parocin
Promeco brand of meloxicam
Ratio-meloxicam
S1734_Selleck
SPECTRUM1504150
STK620505
Squibb brand of meloxicam
TL8005001
Tenaron
UH-AC 62XX
UHAC-62XX
UNII-VG2QF83CGL
UNII-vg2qf83cgl
Uticox
meloxicam
miloxicam
reumoxicam
6
DuloxetineapprovedPhase 3252136434-34-960835
Synonyms:
(+-)-duloxetine
(3S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine
(3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine
(3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(2-thienyl)propan-1-amine
(3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
(S)-Duloxetine
(S)-N-Methyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine
116539-59-4
AC-15704
AC1L1U0Q
AC1Q57H7
C18H19NOS
CHEBI:36795
CHEMBL1175
CID60835
CPD000449282
Cymbalta
D07880
DB00476
Duloxetine
Duloxetine (INN)
Duloxetine HCl
 
Duloxetine Hydrochloride
Duloxetine Hydrochloride 20 mg
Duloxetine Hydrochloride 30 mg
Duloxetine Hydrochloride 60 mg
Duloxetine [INN:BAN]
HMS2051I05
HSDB 7368
LS-172322
LY 248686
MLS000758267
MLS001423946
MolPort-003-847-038
NCGC00164559-01
PDSP1_000969
PDSP1_001385
PDSP2_000953
PDSP2_001369
SAM001247059
SMR000449282
UNII-O5TNM5N07U
Yentreve
Yentreve (TN)
duloxetine
duloxetine, (+)-isomer
7
DopamineapprovedPhase 3281462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
8
SerotoninPhase 3285350-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
9Insulin, Globin ZincPhase 34069
10insulinPhase 34069
11Aluminum sulfatePhase 377
12
Calcium carbonateapprovedPhase 2185
Synonyms:
7 Select Antacid
Alka-seltzer Fruit Chews
Alka-seltzer Heartburn Reliefchews
Alka-seltzer Heartburn Reliefchews Cool Mint
Alka-seltzer Heartburn Reliefchews Strawberry
Antacid
Antacid Extra Strength Assorted Berries
Antacid Ultra Strength
Antacid Ultra Strength Assorted Berries
Antacid extra strength
Antacid maximum strength ultra
Being Well Antacid
CaCO3
Calcid ANTACID CALCIUM SUPPLEMENT REGULAR STRENGTH
Calcium Antacid
Calcium Antacid extra strength
Calcium Carbonate
Calcium Carbonate (Antacid)
Calcium Carbonate Chewable Antacid
Calcium Carbonate Extra Strength Antacid
Calcium carbonate
Calcium carbonate (1:1)
Calciumcarbonat
Carbonate de calcium
Carbonato de calcio
Carbonic acid calcium salt (1:1)
Care One Calcium Antacid
Childrens Chewable Antacid
Childrens Pepto
Childrens Stomach Relief
Chooz
D-cal
D-cal Kids
Dg Health Antacid Calcium Supplement
Dg Health Antacid Calcium Supplement regular strength
Dg Health Calcium Antacid
Dg Health Calcium Antacid extra strength
Equaline Antacid
Equaline Antacid regular strength
Equate Antacid
Equate Antacid regular strength
Exchange Select Calcium Antacid
Extra Strength
Extra Strength antacid calcium supplement
First Aid Shot Therapy Upset Stomach Relief
Formu Care Calcium Antacid
Good Sense Antacid
Green Guard Stomach Relief
Health Mart Calcium Antacid
Health Mart Calcium Antacid Assorted Fruit
 
Healthmart Calcium Antacid
Healthy Accents Antacid
Healthy Accents Antacid extra strength
Healthy Mama TAME THE FLAME
Heartburn Relief To Go
His Ulc Mint Blue
Kalziumkarbonat
Kirkland Signature Antacid
Kohlensaurer kalk
Leader Antacid
Leader Antacid Regular Strength
Maximum Strength
Medi First Antacid
Medi First Plus Antacid
Medi-first Antacid
Medi-first Plus Antacid
Medique Alcalak
Medique Ban-acid Maximum Strength 750
Meijer Softchews
Miralac
Miralac Antacid
Moore Medical Antacid
Nutralox
Physicianscare Antacid
Plus Pharma Calcium Antacid
Precipitated calcium carbonate
Regular Strength
Regular Strength Antacid Calcium Supplement
Rexall Antacid
Rx Act Antacid extra strength
Select Brand Antacid Assorted Berries
Sunmark Assorted Berries
Sunmark Calcium Antacid
Sunmark Calcium Antacid REGULAR STRENGTH
Sunmark Calcium Antacid extra strength
Sunmark Calcium Antacid regular strength
Sunmark Smooth Antacid
Titralac
Topcare Antacid Calcium
Topcare Antacid Calcium Extra Strength
Topcare Antacid Calcium Regular Strength
Topcare Antacid Calcium Ultra Strength
Trial Antacid
Tums
Tums Chewy Delights
Tums EX
Tums Smoothies
Tums ULTRA
Tums freshers
Ultrastrength
Welby Health Antacid
e 170
13
Ergocalciferolapproved, nutraceuticalPhase 288550-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
14
Cholecalciferolapproved, nutraceuticalPhase 275567-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7e)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
 
Colecalciferol
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
calciol
cholecalciferol
delta-D
vitamin d-3
15ErgocalciferolsPhase 2885
16Calcium, DietaryPhase 23529
17vitamin dPhase 21463
18Vitamin D2NutraceuticalPhase 2885
19CalciferolNutraceuticalPhase 21028
20Calcium SupplementNutraceuticalPhase 247

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Bisphosphonate Therapy for Osteogenesis ImperfectaCompletedNCT00159419Phase 4
2Meloxicam [Mobic] in Juvenile Rheumatoid Arthritis (JRA)CompletedNCT00034853Phase 3
3A Study of Duloxetine in Adolescents With Juvenile Primary Fibromyalgia SyndromeRecruitingNCT01237587Phase 3
4Alendronate Osteoporosis StudyActive, not recruitingNCT00277251Phase 2, Phase 3
5A Phase III Study to Investigate the Impact of Diamyd in Patients Newly Diagnosed With Type 1 Diabetes (USA)- DIAPREVENTTerminatedNCT00751842Phase 3
6Phase II Study of Alendronate Sodium in Children With High-Turnover Idiopathic Juvenile OsteoporosisCompletedNCT00010439Phase 2
7Treatment of Childhood Osteoporosis With Alendronate (Fosamax)CompletedNCT00001720Phase 2
8Safety and Efficacy of Alendronate (Fosamax) in Children With OsteoporosisCompletedNCT00259857Phase 2
9Denosumab for Glucocorticoid-treated Children With Rheumatic DisordersNot yet recruitingNCT02418273Phase 1, Phase 2
10Alendronate in Juvenile OsteoporosisCompletedNCT00920075
11The Influence of Bisphosphonates in the Oral Cavity in ChildrenCompletedNCT00402064
12Rheumatology Clinical RegistryRecruitingNCT01813409
13Spine Quantitative Computed Tomography (QCT)Active, not recruitingNCT00762879
14Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence StudyActive, not recruitingNCT01663129

Search NIH Clinical Center for Idiopathic Juvenile Osteoporosis

Genetic Tests for Idiopathic Juvenile Osteoporosis

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Anatomical Context for Idiopathic Juvenile Osteoporosis

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MalaCards organs/tissues related to Idiopathic Juvenile Osteoporosis:

33
Bone, Testes, Skin

Animal Models for Idiopathic Juvenile Osteoporosis or affiliated genes

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MGI Mouse Phenotypes related to Idiopathic Juvenile Osteoporosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.8COL1A1, DKK1, LRP5, WNT1, WNT3A
2MP:00053778.6CALCA, COL1A1, IGF1, WNT1, WNT3A
3MP:00053718.5COL1A1, DKK1, IGF1, LRP5, WNT3A
4MP:00053698.3COL1A1, IGF1, IGFBP3, WNT1, WNT3A
5MP:00053808.3CALCA, COL1A1, DKK1, LRP5, WNT1, WNT3A
6MP:00053887.8CALCA, COL1A1, DKK1, IGF1, WNT1, WNT3A
7MP:00036317.2CALCA, COL1A1, DKK1, IGF1, LRP5, WNT1
8MP:00053907.0CALCA, COL1A1, DKK1, GC, IGF1, LRP5
9MP:00053766.9CALCA, COL1A1, DKK1, GC, IGF1, IGFBP3

Publications for Idiopathic Juvenile Osteoporosis

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Articles related to Idiopathic Juvenile Osteoporosis:

(show all 40)
idTitleAuthorsYear
1
Idiopathic juvenile osteoporosis: A case report and review of the literature. (25768278)
2015
2
Radiographic and MR Imaging Findings of the Spine after Bisphosphonate Treatment, in a Child with Idiopathic Juvenile Osteoporosis. (25688321)
2015
3
Evidence of Altered Matrix Composition in Iliac Crest Biopsies from Patients with Idiopathic Juvenile Osteoporosis. (26539896)
2015
4
Idiopathic Juvenile Osteoporosis: Clinical Experience from a Single Centre and Screening of LRP5 and LRP6 Genes. (25783012)
2015
5
Idiopathic Juvenile Osteoporosis: A Case Report. (26436063)
2015
6
Idiopathic juvenile osteoporosis: a cross-sectional single-centre experience with bone histomorphometry and quantitative computed tomography. (23418950)
2013
7
Pamidronate treatment stimulates the onset of recovery phase reducing fracture rate and skeletal deformities in patients with idiopathic juvenile osteoporosis: comparison with untreated patients. (23549954)
2013
8
Idiopathic juvenile osteoporosis--an analysis of the muscle-bone relationship. (16951909)
2006
9
Idiopathic juvenile osteoporosis. (11973603)
2002
10
The bone formation defect in idiopathic juvenile osteoporosis is surface-specific. (12110417)
2002
11
Osteoporosis in children and adolescent girls: case report of idiopathic juvenile osteoporosis and review of the literature. (11496161)
2001
12
Clinical evaluation of patients with idiopathic juvenile osteoporosis. (11497372)
2001
13
Just taller or more bone? The impact of growth hormone on osteogenesis imperfecta and idiopathic juvenile osteoporosis. (11086654)
2000
14
Idiopathic juvenile osteoporosis. (10818429)
2000
15
Deficient bone formation in idiopathic juvenile osteoporosis: a histomorphometric study of cancellous iliac bone. (10804027)
2000
16
Difficulty walking. A presentation of idiopathic juvenile osteoporosis. (9458225)
1998
17
Collagen peptides in osteogenesis imperfecta, idiopathic juvenile osteoporosis and Ehlers--Danlos syndrome. (8816205)
1996
18
Idiopathic juvenile osteoporosis. An unusual cause of back pain in an adolescent. (8581446)
1995
19
Idiopathic juvenile osteoporosis: five-year case follow-up. (7613264)
1995
20
Estrogen and diclofenac sodium therapy in a prepubertal female with idiopathic juvenile osteoporosis. (7584708)
1995
21
Type I collagen biosynthesis by skin fibroblasts from patients with idiopathic juvenile osteoporosis. (7671570)
1995
22
Fracture of the humerus in ball throwers. A consequence of idiopathic juvenile osteoporosis in a female handball player? (7882130)
1995
23
Case report: effect of pregnancy on idiopathic juvenile osteoporosis. (7900745)
1995
24
Idiopathic juvenile osteoporosis: experience of twenty-one patients. (7881843)
1995
25
Idiopathic juvenile osteoporosis. (8434248)
1993
26
Idiopathic juvenile osteoporosis: evidence of normal osteoblast function by 1,25-dihydroxyvitamin D3 stimulation test. (1393771)
1992
27
Mineral metabolism and calcitriol therapy in idiopathic juvenile osteoporosis. (2012031)
1991
28
Effect of calcitonin replacement therapy in idiopathic juvenile osteoporosis. (3177335)
1988
29
Bone metabolism in idiopathic juvenile osteoporosis: a case report. (6839191)
1983
30
Idiopathic juvenile osteoporosis and scoliosis. (7130387)
1982
31
Calcitriol deficiency in idiopathic juvenile osteoporosis. (6896958)
1982
32
Spinal deformity in idiopathic juvenile osteoporosis. (7209670)
1981
33
Idiopathic juvenile osteoporosis. (6784514)
1981
34
Idiopathic juvenile osteoporosis. (474538)
1979
35
Idiopathic juvenile osteoporosis. (314235)
1979
36
A case-report of idiopathic juvenile osteoporosis with particular reference to 47-calcium absorption. (891571)
1977
37
Idiopathic juvenile osteoporosis. (5459928)
1970
38
Idiopathic juvenile osteoporosis: report of a case and review of the literature. (4908113)
1969
39
Idiopathic juvenile osteoporosis. (5363391)
1969
40
IDIOPATHIC JUVENILE OSTEOPOROSIS. (14319616)
1965

Variations for Idiopathic Juvenile Osteoporosis

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Clinvar genetic disease variations for Idiopathic Juvenile Osteoporosis:

5
id Gene Variation Type Significance SNP ID Assembly Location
1WNT1NM_005430.3(WNT1): c.859dupC (p.His287Profs)duplicationPathogenic, risk factorrs387907353GRCh37Chr 12, 49375169: 49375169
2WNT1NM_005430.3(WNT1): c.703C> T (p.Arg235Trp)single nucleotide variantrisk factorrs387907359GRCh37Chr 12, 49375013: 49375013
3WNT1NM_005430.3(WNT1): c.652T> G (p.Cys218Gly)single nucleotide variantrisk factorrs397514702GRCh37Chr 12, 49374962: 49374962

Expression for genes affiliated with Idiopathic Juvenile Osteoporosis

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Search GEO for disease gene expression data for Idiopathic Juvenile Osteoporosis.

Pathways for genes affiliated with Idiopathic Juvenile Osteoporosis

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Pathways related to Idiopathic Juvenile Osteoporosis according to GeneCards Suite gene sharing:

(show all 21)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7LRP5, WNT3A
29.6BGLAP, COL1A1
3
Wnt Signaling Pathway (WikiPathways)
Show member pathways
9.4BGLAP, COL1A1
49.4LRP5, WNT1, WNT3A
5
Show member pathways
9.4CALCA, WNT1, WNT3A
69.4DKK1, LRP5, WNT1
79.3IGF1, IGFBP3
89.3DKK1, LRP5, WNT3A
9
Show member pathways
9.3DKK1, LRP5, WNT3A
109.1IGF1, WNT1, WNT3A
11
Show member pathways
9.1IGF1, WNT1, WNT3A
129.1IGF1, WNT1, WNT3A
139.1IGF1, LRP5, WNT3A
14
Show member pathways
9.0DKK1, LRP5, WNT1, WNT3A
159.0DKK1, LRP5, WNT1, WNT3A
169.0DKK1, LRP5, WNT1, WNT3A
17
Show member pathways
9.0DKK1, LRP5, WNT1, WNT3A
18
Wnt signaling pathway (KEGG)
Show member pathways
9.0DKK1, LRP5, WNT1, WNT3A
199.0DKK1, IGF1, WNT3A
208.8COL1A1, IGF1, IGFBP3
218.6BGLAP, CALCA, COL1A1, IGF1

GO Terms for genes affiliated with Idiopathic Juvenile Osteoporosis

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Cellular components related to Idiopathic Juvenile Osteoporosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1insulin-like growth factor binding protein complexGO:001694210.1IGF1, IGFBP3
2insulin-like growth factor ternary complexGO:004256710.1IGF1, IGFBP3
3endoplasmic reticulum lumenGO:00057889.1COL1A1, WNT1, WNT3A
4extracellular spaceGO:00056156.1BGLAP, CALCA, COL1A1, DKK1, GC, IGF1
5extracellular regionGO:00055765.8BGLAP, CALCA, COL1A1, DKK1, GC, IGF1

Biological processes related to Idiopathic Juvenile Osteoporosis according to GeneCards Suite gene sharing:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of dermatome developmentGO:006118410.5WNT1, WNT3A
2osteoblast developmentGO:000207610.4BGLAP, LRP5
3spinal cord association neuron differentiationGO:002152710.4WNT1, WNT3A
4negative regulation of fat cell differentiationGO:004559910.3WNT1, WNT3A
5vasculature developmentGO:000194410.3CALCA, LRP5
6negative regulation of cell-substrate adhesionGO:001081210.3COL1A1, WNT1
7negative regulation of BMP signaling pathwayGO:003051410.2DKK1, WNT1
8mammary gland developmentGO:003087910.0IGF1, WNT3A
9positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.0LRP5, WNT1, WNT3A
10canonical Wnt signaling pathwayGO:006007010.0LRP5, WNT1, WNT3A
11face morphogenesisGO:00603259.9COL1A1, DKK1
12Wnt signaling pathwayGO:00160559.7LRP5, WNT1, WNT3A
13bone developmentGO:00603489.7BGLAP, LRP5, WNT1
14positive regulation of insulin-like growth factor receptor signaling pathwayGO:00435689.7IGF1, IGFBP3, WNT1
15response to steroid hormoneGO:00485459.5COL1A1, GC
16positive regulation of mitotic nuclear divisionGO:00458409.5IGF1, LRP5
17positive regulation of canonical Wnt signaling pathwayGO:00902639.3COL1A1, LRP5, WNT1, WNT3A
18skeletal system developmentGO:00015019.2BGLAP, COL1A1, IGF1
19positive regulation of cell proliferationGO:00082849.1IGF1, LRP5, WNT1, WNT3A
20response to nutrient levelsGO:00316679.0BGLAP, COL1A1, GC
21osteoblast differentiationGO:00016499.0BGLAP, COL1A1, IGFBP3, WNT3A
22platelet activationGO:00301688.6COL1A1, IGF1, WNT3A
23positive regulation of transcription, DNA-templatedGO:00458938.6COL1A1, IGF1, LRP5, WNT1, WNT3A

Molecular functions related to Idiopathic Juvenile Osteoporosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor agonist activityGO:00480189.9WNT1, WNT3A
2frizzled bindingGO:00051099.8WNT1, WNT3A

Sources for Idiopathic Juvenile Osteoporosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
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29ICD9CM
30IUPHAR
31KEGG
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38MGI
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66UMLS via Orphanet