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IPF
MCID: IDP003
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Idiopathic Pulmonary Fibrosis malady |
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Sources: 6Disease Ontology, 30NIH Rare Diseases, 17Genetics Home Reference, 44Wikipedia, 33OMIM, 22MalaCards See all sources Export this MalaCard |
Disease Ontology: A idiopathic interstitial pneumonia which is a distinctive type of chronic fibrosing interstitial pneumonia with thick scarring in the lung creating a honeycomb appearance. the main symptoms start insidiously as shortness of breath on exertion, cough, and diminished stamina. other common complaints include weight loss and fatigue. the level of oxygen in the blood decreases, and the skin may take on a bluish tinge (called cyanosis) and the ends of the fingers may become thick or club-shape. in most people, symptoms worsen over a period ranging from about 6 months to several years.6
MalaCards: Idiopathic Pulmonary Fibrosis, also known as familial idiopathic pulmonary fibrosis, is related to acute interstitial pneumonia and interstitial lung disease. An important gene associated with Idiopathic Pulmonary Fibrosis is ELMOD2 (ELMO/CED-12 domain containing 2), and among its related pathways are Glioma Invasiveness and Actin-Based Motility by Rho Family GTPases. The drug oxygen and the compounds gp 130 and acth have been mentioned in the context of this disorder. Affiliated tissues include thymus, brain and smooth muscle, and related mouse phenotypes are respiratory system and embryogenesis. NIH Rare Diseases: Idiopathic pulmonary fibrosis is a condition in which tissue deep in the lungs becomes thick and stiff, or scarred, over time. As a result the lungs lose their ability to move oxygen to the brain and throughout the body. Common symptoms include shortness of breath, and dry, hacking cough. “Idiopathic” refers to cases that’s cause is unknown.30 Genetics Home Reference: Idiopathic pulmonary fibrosis is a chronic, progressive lung disease. This condition causes scar tissue (fibrosis) to build up in the lungs, which makes the lungs unable to transport oxygen into the bloodstream effectively. The disease usually affects people between the ages of 50 and 70.17 Wikipedia: Idiopathic pulmonary fibrosis (IPF) (or cryptogenic fibrosing alveolitis (CFA) or idiopathic fibrosing...44 more... OMIM: 178500 |
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Sources: 6Disease Ontology, 30NIH Rare Diseases, 17Genetics Home Reference, 8DISEASES, 43UMLS, 33OMIM, 32Novoseek , 24MeSH See all sources |
Aliases & Descriptions:
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Sources: 33OMIM See all sources |
Clinical features from OMIM: 178500
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 21LifeMap Discovery™, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for idiopathic pulmonary fibrosis Drug clinical trials:Search ClinicalTrials for idiopathic pulmonary fibrosis Search NIH Clinical Center for idiopathic pulmonary fibrosis Search CenterWatch for idiopathic pulmonary fibrosis Inferred drug relations via UMLS/NDF-RT:43 28 oxygenCell-based therapeutics:![]() The database of embryonic development, stem cell research and regenerative medicine Stem-Cell-Based therapeutic approaches for idiopathic pulmonary fibrosis:
Embryonic/Adult Cultured Cells Related to idiopathic pulmonary fibrosis:
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to idiopathic pulmonary fibrosis:22Thymus, Brain, Smooth muscle, Lung, Skin, Placenta, Monocytes, T cells, B cells, Endothelial
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to idiopathic pulmonary fibrosis:25 (show all 27)
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Sources: 35PubMed See all sources |
Articles related to idiopathic pulmonary fibrosis:(show top 50) (show all 206)
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Sources: 1BioGPS See all sources |
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Sources: 36QIAGEN, 20KEGG See all sources |
Pathways related to idiopathic pulmonary fibrosis according to GeneDecks:(show top 50) (show all 182)
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Sources: 32Novoseek , 9DrugBank, 18HMDB, 42Tocris Bioscience, 34PharmGKB See all sources |
Compounds related to idiopathic pulmonary fibrosis according to GeneDecks:(show top 50) (show all 411)
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Sources: 12Gene Ontology See all sources |
Cellular components related to idiopathic pulmonary fibrosis according to GeneDecks:
Biological processes related to idiopathic pulmonary fibrosis according to GeneDecks:(show top 50) (show all 91)
Molecular functions related to idiopathic pulmonary fibrosis according to GeneDecks:(show all 8)
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