MCID: IDP041
MIFTS: 27

Idiopathic Recurrent Pericarditis malady

Bone diseases, Rare diseases categories

Aliases & Classifications for Idiopathic Recurrent Pericarditis

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Sources:
51Orphanet, 28ICD10 via Orphanet
See all sources

Aliases & Descriptions for Idiopathic Recurrent Pericarditis:

Name: Idiopathic Recurrent Pericarditis 51
 
Idiopathic Relapsing Pericarditis 51


Classifications:



Characteristics (Orphanet epidemiological data):

51
idiopathic recurrent pericarditis:
Inheritance: Not applicable; Age of onset: All ages


External Ids:

Orphanet51 251307
ICD10 via Orphanet28 I09.2

Summaries for Idiopathic Recurrent Pericarditis

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MalaCards based summary: Idiopathic Recurrent Pericarditis, also known as idiopathic relapsing pericarditis, is related to pericarditis and neonatal intrahepatic cholestasis due to citrin deficiency. An important gene associated with Idiopathic Recurrent Pericarditis is TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A), and among its related pathways are Alzheimers disease and Adipocytokine signaling pathway. Affiliated tissues include bone, and related mouse phenotypes are skeleton and integument.

Related Diseases for Idiopathic Recurrent Pericarditis

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Diseases related to Idiopathic Recurrent Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
idRelated DiseaseScoreTop Affiliating Genes
1pericarditis10.8
2neonatal intrahepatic cholestasis due to citrin deficiency10.2MEFV, TNFRSF1A
3non-immunoglobulin-mediated membranoproliferative glomerulonephritis10.2MEFV, TNFRSF1A
4periodic fever, familial10.2MEFV, TNFRSF1A
5psoriatic arthritis10.2
6arthritis10.2
7renal adenoma10.1MEFV, TNFRSF1A
8cinca syndrome10.1MEFV, TNFRSF1A
9muckle-wells syndrome10.1MEFV, TNFRSF1A
10familial colorectal cancer10.1MEFV, TNFRSF1A
11wells-jankovic syndrome10.1MEFV, TNFRSF1A
12senile angioma10.1MEFV, TNFRSF1A
13familial mediterranean fever, ad10.1MEFV, TNFRSF1A
14pericardium cancer10.1MEFV, TNFRSF1A
15amyloidosis, familial visceral10.1MEFV, TNFRSF1A
16noonan syndrome 210.1ADIPOQ, LEP
17clear cell squamous cell skin carcinoma10.1ADIPOQ, LEP
18best vitelliform macular dystrophy10.1ADIPOQ, LEP
19multiple symmetrical lipomatosis10.1ADIPOQ, LEP
20endodermal sinus tumor10.0ADIPOQ, LEP
21sex cord-gonadal stromal tumor10.0ADIPOQ, LEP
22fallopian tube leiomyoma10.0ADIPOQ, LEP
23sleep disorder10.0ADIPOQ, LEP
24eccrine adenocarcinoma10.0ADIPOQ, LEP
25hyperimmunoglobulin syndrome9.9ADIPOQ, LEP
26lymphedema9.9ADIPOQ, LEP, TNFRSF1A
27lipomatosis9.9ADIPOQ, LEP
28familial abdominal aortic aneurysm9.9ADIPOQ, RETN
29ureter cancer9.8LEP, RETN
30angelman syndrome9.8ADIPOQ, LEP
31acquired hemophilia9.8ADIPOQ, LEP, RETN
32macrotrabecular hepatoblastoma9.8ADIPOQ, LEP, RETN
33nondystrophic myotonia9.8ADIPOQ, LEP, RETN
34corpus callosum agenesis double urinary collecting9.8ADIPOQ, LEP, RETN
35motor neuron disease9.8ADIPOQ, LEP, RETN
36lipid storage disease9.8ADIPOQ, LEP, RETN
37anorexia nervosa9.8ADIPOQ, LEP, RETN
38palmoplantar keratosis9.8ADIPOQ, LEP, RETN
39lactose intolerance9.8ADIPOQ, LEP, RETN
40pseudovascular skin squamous cell carcinoma9.8ADIPOQ, LEP, RETN
41glucosephosphate dehydrogenase deficiency9.8ADIPOQ, LEP, RETN
42acquired polycythemia9.8ADIPOQ, LEP, RETN
43hypertension, essential9.6ADIPOQ, LEP, RETN
44merrf syndrome9.5ADIPOQ, LEP, NAMPT, RETN
45tracheal calcification9.5ADIPOQ, LEP, NAMPT, RETN
46diabetes mellitus, noninsulin-dependent9.5ADIPOQ, LEP, NAMPT, RETN
47diabetes mellitus, insulin-dependent9.5ADIPOQ, LEP, NAMPT, RETN
48obesity9.5ADIPOQ, LEP, NAMPT, RETN
49lethal infantile mitochondrial myopathy9.2ADIPOQ, LEP, MEFV, NAMPT, RETN, TNFRSF1A

Graphical network of the top 20 diseases related to Idiopathic Recurrent Pericarditis:



Diseases related to idiopathic recurrent pericarditis

Symptoms for Idiopathic Recurrent Pericarditis

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Drugs & Therapeutics for Idiopathic Recurrent Pericarditis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1AnakInRa for Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP)CompletedNCT02219828Phase 4

Search NIH Clinical Center for Idiopathic Recurrent Pericarditis

Genetic Tests for Idiopathic Recurrent Pericarditis

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Anatomical Context for Idiopathic Recurrent Pericarditis

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MalaCards organs/tissues related to Idiopathic Recurrent Pericarditis:

33
Bone

Animal Models for Idiopathic Recurrent Pericarditis or affiliated genes

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MGI Mouse Phenotypes related to Idiopathic Recurrent Pericarditis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.9ADIPOQ, LEP, MEFV, TNFRSF1A
2MP:00107718.6ADIPOQ, LEP, MEFV, TNFRSF1A
3MP:00053758.5ADIPOQ, LEP, RETN, TNFRSF1A
4MP:00053798.4ADIPOQ, LEP, NAMPT, TNFRSF1A
5MP:00053708.0ADIPOQ, LEP, MEFV, RETN, TNFRSF1A
6MP:00053877.8ADIPOQ, LEP, MEFV, NAMPT, TNFRSF1A
7MP:00053977.6ADIPOQ, LEP, MEFV, NAMPT, TNFRSF1A
8MP:00053767.1ADIPOQ, LEP, MEFV, NAMPT, RETN, TNFRSF1A

Publications for Idiopathic Recurrent Pericarditis

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Articles related to Idiopathic Recurrent Pericarditis:

(show all 20)
idTitleAuthorsYear
1
Anakinra: an emerging option for refractory idiopathic recurrent pericarditis: a systematic review of published evidence. (26090915)
2015
2
Anakinra for the management of resistant idiopathic recurrent pericarditis. Initial experience in 10 adult cases. (25165036)
2014
3
Acute pericarditis as the first manifestation of familial Mediterranean fever: a possible relationship with idiopathic recurrent pericarditis. (25088882)
2014
4
Idiopathic recurrent pericarditis as an immune-mediated disease: current insights into pathogenesis and emerging treatment options. (25307995)
2014
5
Idiopathic recurrent pericarditis treated successfully with tumour necrosis factor alpha blocking agents (anti-TNF-I+). (23711245)
2013
6
New insights in the pathogenesis and therapy of idiopathic recurrent pericarditis in children. (23981280)
2013
7
Leptin, adiponectin, resistin, visfatin serum levels and idiopathic recurrent pericarditis: biomarkers of disease activity? A preliminary report. (23137677)
2013
8
Role of autoimmunity and autoinflammation in the pathogenesis of idiopathic recurrent pericarditis. (21170606)
2013
9
Efficacy of an interleukin-1I^ receptor antagonist (anakinra) in idiopathic recurrent pericarditis. (23052671)
2013
10
Successful treatment of idiopathic recurrent pericarditis with interleukin-1 receptor antagonist (Anakinra). (23463131)
2013
11
Resolution of idiopathic recurrent pericarditis in a psoriatic arthritis patient treated with etanercept. (22155373)
2012
12
Successful treatment of adult patients with idiopathic recurrent pericarditis with an interleukin-1 receptor antagonist (anakinra). (22704870)
2012
13
Successful treatment of idiopathic recurrent pericarditis in children with interleukin-1beta receptor antagonist (anakinra): an unrecognized autoinflammatory disease? (19116906)
2009
14
Idiopathic recurrent pericarditis: searching for Ariadne's thread. (19767277)
2009
15
Pathogenetic mechanisms, new drugs, and old problems in idiopathic recurrent pericarditis: comment on the article by Picco et al. (19644862)
2009
16
Idiopathic recurrent pericarditis refractory to colchicine treatment can reveal tumor necrosis factor receptor-associated periodic syndrome. (20074469)
2009
17
Prognosis of idiopathic recurrent pericarditis as determined from previously published reports. (17826391)
2007
18
Efficacy of high-dose intravenous immunoglobulins in two patients with idiopathic recurrent pericarditis refractory to previous immunosuppressive treatment. (12690925)
2003
19
IDIOPATHIC RECURRENT PERICARDITIS; A CASE REPORT. (14224691)
1965
20
Idiopathic recurrent pericarditis; comparison with the postcommissurotomy syndrome; considerations of etiology and treatment. (14361444)
1955

Variations for Idiopathic Recurrent Pericarditis

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Expression for genes affiliated with Idiopathic Recurrent Pericarditis

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Search GEO for disease gene expression data for Idiopathic Recurrent Pericarditis.

Pathways for genes affiliated with Idiopathic Recurrent Pericarditis

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GO Terms for genes affiliated with Idiopathic Recurrent Pericarditis

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Cellular components related to Idiopathic Recurrent Pericarditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.9ADIPOQ, LEP, RETN, TNFRSF1A
2extracellular spaceGO:00056157.6ADIPOQ, LEP, NAMPT, RETN, TNFRSF1A

Biological processes related to Idiopathic Recurrent Pericarditis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1response to nutrientGO:00075849.8ADIPOQ, LEP
2adipose tissue developmentGO:00606129.7LEP, NAMPT
3fatty acid beta-oxidationGO:00066359.7ADIPOQ, LEP
4negative regulation of inflammatory responseGO:00507289.4ADIPOQ, MEFV, TNFRSF1A
5female pregnancyGO:00075659.2LEP, NAMPT
6glucose homeostasisGO:00425939.1ADIPOQ, LEP
7circadian rhythmGO:00076238.8ADIPOQ, LEP, NAMPT

Molecular functions related to Idiopathic Recurrent Pericarditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051798.6ADIPOQ, LEP, RETN

Sources for Idiopathic Recurrent Pericarditis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet