MCID: IDP041
MIFTS: 29

Idiopathic Recurrent Pericarditis malady

Categories: Bone diseases, Rare diseases

Aliases & Classifications for Idiopathic Recurrent Pericarditis

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Sources:
52Orphanet, 29ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Idiopathic Recurrent Pericarditis:

Name: Idiopathic Recurrent Pericarditis 52
 
Idiopathic Relapsing Pericarditis 52

Characteristics:

Orphanet epidemiological data:

52
idiopathic recurrent pericarditis:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Orphanet52 ORPHA251307
ICD10 via Orphanet29 I09.2

Summaries for Idiopathic Recurrent Pericarditis

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MalaCards based summary: Idiopathic Recurrent Pericarditis, also known as idiopathic relapsing pericarditis, is related to pericarditis and autosomal recessive secondary polycythemia not associated with vhl gene. An important gene associated with Idiopathic Recurrent Pericarditis is TNFRSF1A (TNF Receptor Superfamily Member 1A), and among its related pathways are Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers and Alzheimer's disease. Affiliated tissues include bone, and related mouse phenotypes are integument and immune system.

Related Diseases for Idiopathic Recurrent Pericarditis

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Diseases related to Idiopathic Recurrent Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
idRelated DiseaseScoreTop Affiliating Genes
1pericarditis10.4
2autosomal recessive secondary polycythemia not associated with vhl gene10.3MEFV, TNFRSF1A
3adult-onset multiple mitochondrial dna deletion syndrome due to dguok deficiency10.3MEFV, TNFRSF1A
4multiple sclerosis 510.3MEFV, TNFRSF1A
5familial cold-induced inflammatory syndrome 110.3MEFV, TNFRSF1A
6cinca syndrome10.2MEFV, TNFRSF1A
7muckle-wells syndrome10.2MEFV, TNFRSF1A
8nondystrophic myotonia10.2ADIPOQ, LEP
9radioulnar synostosis retinal pigment abnormalities10.2MEFV, TNFRSF1A
10antidepressant type abuse10.2ADIPOQ, LEP
11pyloric stenosis, infantile hypertrophic, 210.2MEFV, TNFRSF1A
12potato nose10.2ADIPOQ, LEP
13nephrosclerosis10.2MEFV, TNFRSF1A
14scleredema adultorum10.2ADIPOQ, LEP
15afibrinogenemia, congenital10.2MEFV, TNFRSF1A
16patellofemoral pain syndrome10.1ADIPOQ, LEP
17hordeolum externum10.1ADIPOQ, LEP
18keratoacanthoma10.1ADIPOQ, LEP
19lymphosarcoma10.1ADIPOQ, LEP
20diabetic encephalopathy10.0ADIPOQ, LEP
21periampullary adenoma10.0ADIPOQ, LEP
22precursor b lymphoblastic lymphoma/leukemia10.0ADIPOQ, LEP
23familial drusen10.0ADIPOQ, RETN
24hypertrichosis9.9ADIPOQ, LEP
25lower gum cancer9.9MEFV, TNFRSF1A
26gemistocytic astrocytoma9.9ADIPOQ, LEP
27lymphoblastic lymphoma9.8ADIPOQ, LEP, TNFRSF1A
28isthmus cancer9.8ADIPOQ, LEP
29psoriatic arthritis9.7
30arthritis9.7
31angelman syndrome9.6ADIPOQ, LEP
32benign peritoneal mesothelioma9.5MEFV, RETN, TNFRSF1A
33tenosynovial giant cell tumor9.5ADIPOQ, LEP, RETN
34corpus callosum dysgenesis cleft spasm9.5ADIPOQ, LEP, RETN
35mucolipidoses9.5ADIPOQ, LEP, RETN
36short bowel syndrome9.5ADIPOQ, LEP, RETN
37femoral neuropathy9.5ADIPOQ, LEP, RETN
38survival motor neuron spinal muscular atrophy9.5ADIPOQ, LEP, RETN
39acatalasemia9.5ADIPOQ, LEP, RETN
40hypertension, essential9.4ADIPOQ, LEP, RETN
41deafness, x-linked 58.9ADIPOQ, LEP, NAMPT, RETN
42tracheal calcification8.9ADIPOQ, LEP, NAMPT, RETN
43neonatal diabetes mellitus8.9ADIPOQ, LEP, NAMPT, RETN
44angiomatous meningioma8.9ADIPOQ, LEP, NAMPT, RETN
45diabetes mellitus, noninsulin-dependent8.8ADIPOQ, LEP, NAMPT, RETN
46hepatic adenoma, somatic8.8ADIPOQ, LEP, NAMPT, RETN
47obesity8.8ADIPOQ, LEP, NAMPT, RETN
48pure mitochondrial myopathy8.0ADIPOQ, LEP, MEFV, NAMPT, RETN, TNFRSF1A

Graphical network of the top 20 diseases related to Idiopathic Recurrent Pericarditis:



Diseases related to idiopathic recurrent pericarditis

Symptoms for Idiopathic Recurrent Pericarditis

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Drugs & Therapeutics for Idiopathic Recurrent Pericarditis

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Drugs for Idiopathic Recurrent Pericarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Menthol21842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol

Interventional clinical trials:

idNameStatusNCT IDPhase
1AnakInRa for Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP)CompletedNCT02219828Phase 4
2Improvement of the Etiological Diagnosis of the PericarditisRecruitingNCT02828085

Search NIH Clinical Center for Idiopathic Recurrent Pericarditis

Genetic Tests for Idiopathic Recurrent Pericarditis

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Anatomical Context for Idiopathic Recurrent Pericarditis

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MalaCards organs/tissues related to Idiopathic Recurrent Pericarditis:

34
Bone

Animal Models for Idiopathic Recurrent Pericarditis or affiliated genes

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MGI Mouse Phenotypes related to Idiopathic Recurrent Pericarditis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.9ADIPOQ, LEP, MEFV, TNFRSF1A
2MP:00053878.2ADIPOQ, LEP, MEFV, NAMPT, TNFRSF1A
3MP:00053758.2ADIPOQ, LEP, RETN, TNFRSF1A
4MP:00053708.1ADIPOQ, LEP, MEFV, RETN, TNFRSF1A
5MP:00053978.0ADIPOQ, LEP, MEFV, NAMPT, TNFRSF1A
6MP:00053767.1ADIPOQ, LEP, MEFV, NAMPT, RETN, TNFRSF1A

Publications for Idiopathic Recurrent Pericarditis

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Articles related to Idiopathic Recurrent Pericarditis:

(show all 22)
idTitleAuthorsYear
1
The Use of IL-1 Receptor Antagonist (Anakinra) in Idiopathic Recurrent Pericarditis: A Narrative Review. (26942035)
2016
2
Usefulness of Novel Immunotherapeutic Strategies for Idiopathic Recurrent Pericarditis. (26742476)
2016
3
Anakinra: an emerging option for refractory idiopathic recurrent pericarditis: a systematic review of published evidence. (26090915)
2015
4
Idiopathic recurrent pericarditis as an immune-mediated disease: current insights into pathogenesis and emerging treatment options. (25307995)
2014
5
Anakinra for the management of resistant idiopathic recurrent pericarditis. Initial experience in 10 adult cases. (25165036)
2014
6
Acute pericarditis as the first manifestation of familial Mediterranean fever: a possible relationship with idiopathic recurrent pericarditis. (25088882)
2014
7
Idiopathic recurrent pericarditis treated successfully with tumour necrosis factor alpha blocking agents (anti-TNF-I+). (23711245)
2013
8
New insights in the pathogenesis and therapy of idiopathic recurrent pericarditis in children. (23981280)
2013
9
Role of autoimmunity and autoinflammation in the pathogenesis of idiopathic recurrent pericarditis. (21170606)
2013
10
Leptin, adiponectin, resistin, visfatin serum levels and idiopathic recurrent pericarditis: biomarkers of disease activity? A preliminary report. (23137677)
2013
11
Efficacy of an interleukin-1I^ receptor antagonist (anakinra) in idiopathic recurrent pericarditis. (23052671)
2013
12
Successful treatment of idiopathic recurrent pericarditis with interleukin-1 receptor antagonist (Anakinra). (23463131)
2013
13
Resolution of idiopathic recurrent pericarditis in a psoriatic arthritis patient treated with etanercept. (22155373)
2012
14
Successful treatment of adult patients with idiopathic recurrent pericarditis with an interleukin-1 receptor antagonist (anakinra). (22704870)
2012
15
Pathogenetic mechanisms, new drugs, and old problems in idiopathic recurrent pericarditis: comment on the article by Picco et al. (19644862)
2009
16
Idiopathic recurrent pericarditis refractory to colchicine treatment can reveal tumor necrosis factor receptor-associated periodic syndrome. (20074469)
2009
17
Successful treatment of idiopathic recurrent pericarditis in children with interleukin-1beta receptor antagonist (anakinra): an unrecognized autoinflammatory disease? (19116906)
2009
18
Idiopathic recurrent pericarditis: searching for Ariadne's thread. (19767277)
2009
19
Prognosis of idiopathic recurrent pericarditis as determined from previously published reports. (17826391)
2007
20
Efficacy of high-dose intravenous immunoglobulins in two patients with idiopathic recurrent pericarditis refractory to previous immunosuppressive treatment. (12690925)
2003
21
IDIOPATHIC RECURRENT PERICARDITIS; A CASE REPORT. (14224691)
1965
22
Idiopathic recurrent pericarditis; comparison with the postcommissurotomy syndrome; considerations of etiology and treatment. (14361444)
1955

Variations for Idiopathic Recurrent Pericarditis

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Expression for genes affiliated with Idiopathic Recurrent Pericarditis

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Search GEO for disease gene expression data for Idiopathic Recurrent Pericarditis.

Pathways for genes affiliated with Idiopathic Recurrent Pericarditis

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GO Terms for genes affiliated with Idiopathic Recurrent Pericarditis

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Cellular components related to Idiopathic Recurrent Pericarditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.0ADIPOQ, LEP, RETN, TNFRSF1A
2extracellular spaceGO:00056157.6ADIPOQ, LEP, NAMPT, RETN, TNFRSF1A

Biological processes related to Idiopathic Recurrent Pericarditis according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1adipose tissue developmentGO:00606129.9LEP, NAMPT
2fatty acid beta-oxidationGO:00066359.8ADIPOQ, LEP
3response to nutrientGO:00075849.8ADIPOQ, LEP
4glucose homeostasisGO:00425939.7ADIPOQ, LEP
5glucose metabolic processGO:00060069.7ADIPOQ, LEP
6response to insulinGO:00328689.5LEP, RETN
7negative regulation of inflammatory responseGO:00507289.5ADIPOQ, MEFV, TNFRSF1A
8response to nutrient levelsGO:00316679.5ADIPOQ, LEP
9female pregnancyGO:00075659.4LEP, NAMPT
10positive regulation of smooth muscle cell proliferationGO:00486619.4NAMPT, RETN
11response to activityGO:00148239.2ADIPOQ, LEP
12circadian rhythmGO:00076238.9ADIPOQ, LEP, NAMPT

Molecular functions related to Idiopathic Recurrent Pericarditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051798.7ADIPOQ, LEP, RETN

Sources for Idiopathic Recurrent Pericarditis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet