Aliases & Classifications for Ileitis

MalaCards integrated aliases for Ileitis:

Name: Ileitis 12 51 41 14 69
Crohn's Ileitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060189
ICD10 32 K52.9
MeSH 41 D007079
NCIt 46 C84782
SNOMED-CT 64 52457000
UMLS 69 C0020877

Summaries for Ileitis

Disease Ontology : 12 An inflammatory bowel disease characterized by inflammation located in ileum, has symptom diarrhea, has symptom abdominal pain, often in the right lower quadrant, has symptom weight loss.

MalaCards based summary : Ileitis, also known as crohn's ileitis, is related to crohn's disease and pouchitis, and has symptoms including diarrhea, abdominal pain and weight loss. An important gene associated with Ileitis is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Clarithromycin and Clofazimine have been mentioned in the context of this disorder. Affiliated tissues include ileum, t cells and colon, and related phenotypes are homeostasis/metabolism and hematopoietic system

Related Diseases for Ileitis

Diseases related to Ileitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 218)
# Related Disease Score Top Affiliating Genes
1 crohn's disease 31.9 IL6 NOD2 TLR4 TLR9 TNF
2 pouchitis 30.8 NOD2 TLR4
3 lymphadenitis 30.3 NOD2 TLR4 TNF
4 mesenteric lymphadenitis 30.3 IL6 NOD2 TLR2
5 ileocolitis 30.1 NOD2 TNF
6 cystitis 29.9 IL6 TLR4 TNF
7 peritonitis 29.9 IL6 TLR2 TNF
8 ulcerative colitis 29.8 IL6 MPO NOD2 TLR4 TNF
9 appendicitis 29.8 IL6 MPO TNF
10 typhoid fever 29.6 IL6 TLR4 TLR5 TNF
11 mycobacterium tuberculosis 1 29.0 IL17A TLR2 TLR4 TLR9 TNF
12 colitis 29.0 IL17A IL6 MPO NOD2 TLR4 TLR9
13 inflammatory bowel disease 27.6 IL17A IL6 MPO NOD2 TLR2 TLR4
14 scorpion envenomation 10.5 IL6 TNF
15 spondylarthropathy 10.5 TLR4 TNF
16 prosthetic joint infection 10.5 TLR2 TLR4
17 angioimmunoblastic lymphadenopathy with dysproteinemia 10.5 IL6 TNF
18 critical limb ischemia 10.5 IL6 TNF
19 tympanosclerosis 10.5 TLR4 TNF
20 granulomatous dermatitis 10.4 NOD2 TNF
21 streptococcal toxic-shock syndrome 10.4 IL6 TNF
22 null-cell leukemia 10.4 IL6 TNF
23 periodontitis, chronic 10.4 IL6 TLR2
24 rheumatoid lung disease 10.4 IL17A TNF
25 neurosyphilis 10.4 IL17A TLR2
26 retinitis pigmentosa 55 10.4 IL6 TNF
27 glossitis 10.4 IL6 TNF
28 anterior uveitis 10.4 IL6 TLR4 TNF
29 laryngitis 10.4 IL6 TNF
30 trench fever 10.4 TLR2 TLR4 TNF
31 penicilliosis 10.3 TLR2 TLR4 TNF
32 alveolar echinococcosis 10.3 TLR2 TLR4 TNF
33 idiopathic neutropenia 10.3 IL6 TLR4 TNF
34 brucellosis 10.3 IL6 TLR4 TNF
35 pyelonephritis 10.3 IL6 TLR4 TNF
36 scrub typhus 10.3 TLR2 TLR4 TNF
37 aggressive periodontitis 10.3 IL6 TLR4 TNF
38 q fever 10.3 TLR2 TLR4 TNF
39 chorioamnionitis 10.3 IL6 TLR4 TNF
40 haemophilus influenzae 10.3 TLR2 TNF
41 toxic shock syndrome 10.3 IL6 TLR4 TNF
42 posterior urethral valves 10.3 IL6 TNF
43 leprosy 3 10.3 NOD2 TLR2 TNF
44 hidradenitis suppurativa 10.3 IL17A NOD2 TNF
45 hidradenitis 10.3 IL17A NOD2 TNF
46 poems syndrome 10.3 IL6 TNF
47 rosacea 10.3 IL6 TLR2 TNF
48 infective endocarditis 10.3 IL6 TLR2 TNF
49 rheumatic heart disease 10.3 IL6 TLR2 TNF
50 leptospirosis 10.3 IL6 TLR2 TNF

Graphical network of the top 20 diseases related to Ileitis:



Diseases related to Ileitis

Symptoms & Phenotypes for Ileitis

Symptoms:

12
  • diarrhea
  • abdominal pain
  • weight loss

MGI Mouse Phenotypes related to Ileitis:

43 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.18 MPO FABP2 NOD2 IL17A TLR2 CCR3
2 hematopoietic system MP:0005397 10.17 MPO NOD2 IL17A TLR2 CCR3 IL6
3 cellular MP:0005384 10.15 NOD2 CCR3 IL6 CSF2 TLR5 TLR2
4 growth/size/body region MP:0005378 10.11 CSF2 FABP2 NOD2 IL17A IL6 TNF
5 immune system MP:0005387 10.11 MPO NOD2 IL17A TLR2 CCR3 IL6
6 digestive/alimentary MP:0005381 10.08 NOD2 IL17A IL6 TLR5 TLR2 TLR9
7 adipose tissue MP:0005375 10.05 FABP2 IL6 CSF2 TLR5 TLR2 TLR4
8 mortality/aging MP:0010768 9.96 CSF2 MPO NOD2 IL17A IL6 TNF
9 liver/biliary system MP:0005370 9.8 FABP2 IL6 TNF TLR4 TLR5 TLR2
10 renal/urinary system MP:0005367 9.7 FABP2 IL17A IL6 CSF2 TLR2 TLR9
11 respiratory system MP:0005388 9.56 IL17A CCR3 IL6 CSF2 TLR5 TLR2
12 skeleton MP:0005390 9.17 CSF2 NOD2 IL17A IL6 TNF TLR4

Drugs & Therapeutics for Ileitis

Drugs for Ileitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 416)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clarithromycin Approved Phase 4,Phase 3 81103-11-9 84029
2
Clofazimine Approved, Investigational Phase 4,Phase 3 2030-63-9 2794
3
Rifabutin Approved, Investigational Phase 4,Phase 3 72559-06-9 6323490
4
Adalimumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 331731-18-1 16219006
5
Infliximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 170277-31-3
6
Hydrocortisone Approved, Vet_approved Phase 4,Not Applicable 50-23-7 657311 5754
7
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
8
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 83-43-2 6741
9
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-24-8 5755
10
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 428863-50-7
11
Azathioprine Approved Phase 4,Phase 3,Phase 2,Not Applicable 446-86-6 2265
12
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1 51333-22-3 5281004 63006
13
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1994-09-7, 94-09-7 2337
14
Iron Approved Phase 4,Phase 3,Phase 2,Not Applicable 7439-89-6 23925
15
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 85721-33-1 2764
16
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2 73590-58-6 4594
17
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 564-25-0 54671203
18
Azithromycin Approved Phase 4 83905-01-5 53477736 447043 55185
19
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 443-48-1 4173
20
Methotrexate Approved Phase 4,Phase 3,Phase 2,Not Applicable 1959-05-2, 59-05-2 126941
21
Etidronic acid Approved Phase 4 2809-21-4, 7414-83-7 3305
22
Natalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 189261-10-7
23 Vedolizumab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1,Not Applicable 943609-66-3
24
Midazolam Approved, Illicit Phase 4,Phase 1 59467-70-8 4192
25
Ondansetron Approved Phase 4,Phase 3 99614-02-5 4595
26
Everolimus Approved Phase 4 159351-69-6 6442177
27
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1 22916-47-8 4189
28
Sirolimus Approved, Investigational Phase 4 53123-88-9 46835353 6436030 5284616
29
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
30
Dextromethorphan Approved Phase 4,Phase 1 125-71-3 5362449 5360696
31
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 1,Not Applicable 93-14-1 3516
32
Losartan Approved Phase 4 114798-26-4 3961
33
Thioguanine Approved Phase 4 154-42-7 2723601
34
Vancomycin Approved Phase 4,Phase 2 1404-90-6 14969 441141
35
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613 2171
36
Sulfamethazine Approved, Investigational, Vet_approved Phase 4 57-68-1 5327
37
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
38
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 67-97-0 10883523 5280795 6221
39
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 50-14-6 5280793
40 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 1406-16-2
42
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-30-3 6037
43
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Not Applicable 58-05-9 143 6006
44
Menadione Approved, Nutraceutical Phase 4,Phase 1 58-27-5 4055
45
Phytonadione Approved, Investigational, Nutraceutical Phase 4,Phase 1 84-80-0 5284607 4812
46
Caffeine Approved, Nutraceutical Phase 4,Phase 1 58-08-2 2519
47 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
49 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
50 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 1138)

# Name Status NCT ID Phase Drugs
1 Treatment of Crohn's Disease With an Antibiotic Regimen Directed Against Mycobacterium Avium Paratuberculosis Unknown status NCT00513552 Phase 4 Rifabutin, Clarithromycin, and Clofazimine
2 A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Unknown status NCT01632462 Phase 4 VSL#3
3 Use of Combined Measurements of Serum Infliximab and Anti-infliximab Antibodies in the Treatment of Patients With Crohns Disease Failing Infliximab Therapy Unknown status NCT00851565 Phase 4
4 The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease) Unknown status NCT01765998 Phase 4 Probiotic;Placebo
5 Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult Unknown status NCT02056418 Phase 4 corticosteroid
6 Evaluation of PET CT in the Management of Patients With Crohn's Disease. Unknown status NCT00731809 Phase 4
7 Comparison of a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis Unknown status NCT00265772 Phase 4 MODULEN IBD (R) (specific Enteral Nutrition);prednisolon
8 Adverse Effects of Glucocorticoid Therapy on Bone in Childhood Crohn's Disease Unknown status NCT00609752 Phase 4 prednisolone
9 Discontinuation of Infliximab Therapy in Patients With Crohn's Disease During Sustained Complete Remission Unknown status NCT01817426 Phase 4 Infliximab
10 VSL#3 Treatment in Children With Crohn's Disease Unknown status NCT00367705 Phase 4
11 Optimizing Cimzia in Crohn's Patients Unknown status NCT01024647 Phase 4
12 The Effect of Probiotics on the Rate of Recovery of Inflammatory Bowel Disease Exacerbation, Endothelial Function, and Markers of Inflammation Unknown status NCT01078935 Phase 4
13 "Efficacy and Safety of Infliximab-biosimilar (Inflectra) Compared to Infliximab-innovator (Remicade) in Patients With Inflammatory Bowel Disease in Remission: the SIMILAR Trial" Unknown status NCT02452151 Phase 4 Infliximab-Biosimilar;Infliximab-Innovator
14 Confocal Endomicroscopy During Endoscopy Unknown status NCT00988273 Phase 4
15 Manipulation of Visceral Sensitivity and Immune System in IBS Unknown status NCT00418340 Phase 4 probiotic (bacterial/dietary supplement)
16 Precision Dosing of Infliximab Versus Conventional Dosing of Infliximab Unknown status NCT02453776 Phase 4 PRECISION dosing Infliximab
17 Diagnostic Accuracy of Capsule Endoscopy in Small Bowel Crohn's Disease Completed NCT00588653 Phase 4
18 Trial of a Treatment Algorithm for the Management of Crohn's Disease Completed NCT01030809 Phase 4
19 SECOND GENERATION COLON CAPSULE ENDOSCOPY (CCE-2) IN PEDIATRIC CROHN'S DISEASE (CD). Completed NCT02199626 Phase 4
20 Efficacy Study of Pneumococcal Vaccination in Crohn's Disease Completed NCT01505855 Phase 4 23-valent polysaccharide pneumococcal vaccine
21 Rapidity of Response to Adalimumab Treatment in Patients With Crohn´s Disease Completed NCT02148718 Phase 4
22 A Study Comparing the Acceptability of Pentasa® Sachets Versus Pentasa® Tablets in Children With Crohn´s Disease Completed NCT00225810 Phase 4 Crohn's Disease
23 VSL#3 Versus Placebo in Maintenance of Remission in Crohn's Disease Completed NCT00114465 Phase 4 VSL#3
24 Evaluation of the Applicability of the CDEIS to Data Obtained by the Colonic Capsule Endoscopy in Crohn Disease Completed NCT01183845 Phase 4
25 The Efficacy of Open Label Infliximab for the Induction and Maintenance of Mucosal Healing in Small Bowel Crohn's Disease Assessed Through Wireless Camera Endoscopy Completed NCT01181765 Phase 4
26 Endoscopic Severity Score of Small Bowel Crohn's Disease With Wireless Capsule Endoscopy Completed NCT00492791 Phase 4
27 Azithromycin Based Therapy for Induction of Remission in Active Pediatric Crohn's Disease Completed NCT01596894 Phase 4 Azithromycin + Metronidazole;Metronidazole
28 Top Down Versus Step Up Strategies in Crohn's Disease Completed NCT00554710 Phase 4 infliximab+azathioprine;methylprednisolone or budesonide
29 Infliximab for the Prevention of Recurrent Crohn's Disease After Surgery Completed NCT00688636 Phase 4 infliximab;placebo
30 The Crohn's Therapy, Resource, Evaluation, and Assessment Tool Registry Completed NCT00553176 Phase 4
31 Adalimumab-psoriasis and Small Bowel Lesions Completed NCT01556672 Phase 4 Adalimumab
32 The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease Completed NCT02010762 Phase 4 Vitamin D;Placebo
33 Risedronate Therapy in the Treatment of Low Bone Mineral Density in Crohn's Disease Completed NCT01215890 Phase 4 risedronate;placebo
34 Vitamin D Supplementation in Adult Crohn's Disease Completed NCT01369667 Phase 4
35 Study Investigating Tailored Treatment With Infliximab for Active Crohn's Disease Completed NCT01442025 Phase 4 Infliximab;Infliximab;Infliximab
36 Early Immunosuppressants in Crohn's Disease Completed NCT00546546 Phase 4 early immunosuppressants (azathioprine, methotrexate)
37 Endoscopic Detection of Dysplasia in Crohn 's Disease Patient Completed NCT01180452 Phase 4
38 Open Label Natalizumab Safety Extension Study for Subjects With Crohn's Disease Completed NCT00280956 Phase 4 natalizumab
39 The Effect of Vitamin K Supplementation on Bone Health in Adult Crohn's Disease Patients Completed NCT01235325 Phase 4
40 Immune Modulation by Parenteral Fish Oil in Patients With Crohn's Disease Completed NCT02349594 Phase 4 Omegaven 10%;Intralipid 20%
41 Vitamin D in Pediatric Crohn's Disease Completed NCT01187459 Phase 4
42 Pneumococcal Vaccination of Crohn Patients Completed NCT01947010 Phase 4
43 Vitd and Barrier Function in IBD Completed NCT01792388 Phase 4
44 An Observational Study of Lymphoma in Patients With Rheumatoid Arthritis or Crohn's Disease. Completed NCT00440817 Phase 4
45 Post Marketing Surveillance of Remicade Completed NCT00724529 Phase 4
46 Remicade Infusion Management Program Completed NCT00723905 Phase 4
47 The NOR-SWITCH Study Completed NCT02148640 Phase 4 Innovator infliximab;Biosimilar infliximab
48 Safety of Accelerated Infliximab Infusions in Patients With Inflammatory Bowel Disease (IBD) Completed NCT01346826 Phase 4 Standard 2 hours-infusion;Accelerated 1 hour-infusion;Accelerated 30 minutes-infusion
49 A Long-term Safety Study of Infliximab (Remicade) Completed NCT00261976 Phase 4 Infliximab (Remicade)
50 Endoscopic Ultrasound (EUS) Guided Treatment With Humira for Crohn's Perianal Fistulas Completed NCT00517296 Phase 4 adalimumab

Search NIH Clinical Center for Ileitis

Cochrane evidence based reviews: ileitis

Genetic Tests for Ileitis

Anatomical Context for Ileitis

The Foundational Model of Anatomy Ontology organs/tissues related to Ileitis:

18
Ileum

MalaCards organs/tissues related to Ileitis:

38
T Cells, Colon, Appendix, Pituitary, B Cells, Breast, Liver

Publications for Ileitis

Articles related to Ileitis:

(show top 50) (show all 150)
# Title Authors Year
1
Histologic features in pediatric ileitis: Is it possible to tip the balance towards Crohn's disease? ( 29397324 )
2018
2
Effective use of ustekinumab for prepouch ileitis without improvement of concomitant pouchitis. ( 29423578 )
2018
3
Histological features of ileitis differentiating pediatric Crohn disease from ulcerative colitis with backwash ileitis. ( 29089273 )
2018
4
Incidence and Long-Term Implications of Prepouch Ileitis: An Observational Study. ( 29369899 )
2018
5
Epicutaneous Tolerance Induction to a Bystander Antigen Abrogates Colitis and Ileitis in Mice. ( 29019858 )
2017
6
Tauroursodeoxycholic acid protects bile acid homeostasis under inflammatory conditions and dampens Crohn's disease-like ileitis. ( 28165466 )
2017
7
Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial. ( 28838644 )
2017
8
A rare case of Crohn's ileitis in a patient with constitutional mismatch repair deficiency. ( 28469372 )
2017
9
Two Cases of Capecitabine-Induced Ileitis in Patients Treated with Radiochemotherapy to the Pelvis and Review of the Literature. ( 28547118 )
2017
10
Chronic ileitis with transmural migration of ingested foreign body treated by laparoscopy. ( 28920530 )
2017
11
Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeruginosa in human microbiota-associated mice. ( 28115993 )
2017
12
An Unusual Cause of Granulomatous Ileitis - With a Brief History of the Pathology of Typhoid. ( 29034754 )
2017
13
Yersinia Enterocolitica Ileitis Mimicking Pediatric Crohn's Disease. ( 28230560 )
2017
14
Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn's Disease. ( 29064015 )
2017
15
Diagnostic Value of Small Bowel Capsule Endoscopy in Isolated Ileitis: A CAPENTRY Study. ( 27889847 )
2017
16
Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn's disease-related ileitis. ( 28108786 )
2017
17
An unexpected cause of terminal ileitis. ( 27729214 )
2017
18
Prepouch Ileitis After Ileal Pouch-anal Anastomosis: Patterns of Presentation and Risk Factors for Failure of Treatment. ( 29240877 )
2017
19
The Ileitis of Ulcerative Colitis. Why Is It Not Crohn's Disease? ( 28079623 )
2017
20
Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model? ( 28560286 )
2017
21
Aspecific ileitis: Crohn's disease or not Crohn's disease? A prospective study. ( 28161731 )
2017
22
Intestinal, extra-intestinal and systemic sequelae of Toxoplasma gondii induced acute ileitis in mice harboring a human gut microbiota. ( 28414794 )
2017
23
Diagnostic Value of Small Bowel Capsule Endoscopy in Isolated Ileitis: A Methodological Mistake. ( 28255834 )
2017
24
Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis. ( 28146004 )
2017
25
Fistulating Crohn's terminal ileitis involving sigmoid colon, left salpinx and urinary bladder: a laparoscopic approach - a video vignette. ( 28603931 )
2017
26
Defective ATG16L1-mediated removal of IRE1I+ drives Crohn's disease-like ileitis. ( 28082357 )
2017
27
A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis. ( 28301579 )
2017
28
Foreign body ileitis: a histopathological mimic of Crohn's disease? ( 28689632 )
2017
29
Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn's disease-related ileitis. ( 28424866 )
2017
30
Post-inflammatory Ileitis Induces Non-neuronal Purinergic Signaling Adjustments of Cholinergic Neurotransmission in the Myenteric Plexus. ( 29167643 )
2017
31
Backwash Is Hogwash: The Clinical Significance of Ileitis in Ulcerative Colitis. ( 28631729 )
2017
32
IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis. ( 26908008 )
2016
33
Donkey milk consumption exerts anti-inflammatory properties by normalizing antimicrobial peptides levels in Paneth's cells in a model of ileitis in mice. ( 27581119 )
2016
34
Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium. ( 27930931 )
2016
35
Visceral Hypersensitivity Is Provoked by 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Ileitis in Rats. ( 27499743 )
2016
36
Tuberculosis terminal ileitis: A forgotten entity mimicking Crohn's disease. ( 27672643 )
2016
37
A novel model for studying ileitis-induced visceral hypersensitivity in goats. ( 27716368 )
2016
38
Sequential Crohn's Ileitis, Ileosigmoidal Fistula, Segmental Sigmoid Polyposis, and Sigmoid Stricture: The Natural History. ( 27466165 )
2016
39
Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn's disease-related ileitis. ( 27591764 )
2016
40
Multiples ileal adenomas in Crohn's disease: Sporadic or ileitis associated dysplasia? ( 28040346 )
2016
41
Clostridium difficile ileitis in a patient, after total colectomy. ( 26903365 )
2016
42
Terminal Ileitis as a Feature of Henoch-SchAPnlein Purpura Masquerading as Crohn Disease in Adults. ( 26906301 )
2016
43
Visceral pain triggered by traction on the ileocecal ligament with ileitis. ( 27757049 )
2016
44
Emergency laparoscopic ileo-colic resection and primary intracorporeal anastomosis for Crohn's acute ileitis with free perforation and faecal peritonitis: first ever reported laparoscopic treatment. ( 26759755 )
2016
45
Capsule Endoscopy for Ileitis with Potential Involvement of Other Sections of the Small Bowel. ( 26880904 )
2016
46
Relapsing Olmesartan-Associated Ileitis. ( 27539736 )
2016
47
Frequency, natural course and clinical significance of symptomatic terminal ileitis. ( 26670338 )
2016
48
Prospective Evaluation of Terminal Ileitis in a Surveillance Population of Patients with Ulcerative Colitis. ( 27580386 )
2016
49
Facing Terminal Ileitis: Going Beyond Crohn's Disease. ( 27785317 )
2016
50
Dietary Creatine as a Possible Novel Treatment for Crohn's Ileitis. ( 28008406 )
2016

Variations for Ileitis

Expression for Ileitis

Search GEO for disease gene expression data for Ileitis.

Pathways for Ileitis

Pathways related to Ileitis according to GeneCards Suite gene sharing:

(show top 50) (show all 52)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.97 CSF2 IL17A IL6 MPO NOD2 TLR2
2
Show member pathways
13.35 CCR3 CSF2 IL17A IL6 TLR2 TLR4
3
Show member pathways
12.94 IL6 NOD2 TLR2 TLR4 TLR5 TLR9
4
Show member pathways
12.77 IL6 TLR2 TLR4 TLR9 TNF
5
Show member pathways
12.69 IL6 TLR2 TLR4 TLR5 TLR9 TNF
6
Show member pathways
12.6 TLR2 TLR4 TLR5 TLR9 TNF
7
Show member pathways
12.56 CCR3 CSF2 IL6 TLR2 TLR4 TNF
8 12.54 IL17A MPO TLR2 TLR9 TNF
9
Show member pathways
12.54 IL17A IL6 NOD2 TLR2 TLR4 TLR5
10
Show member pathways
12.53 IL17A IL6 MPO TNF
11
Show member pathways
12.52 IL6 TLR2 TLR4 TLR5 TLR9 TNF
12
Show member pathways
12.4 CSF2 IL17A IL6 TNF
13
Show member pathways
12.32 CSF2 IL17A IL6 TLR2 TLR5 TNF
14
Show member pathways
12.25 IL6 TLR2 TLR4 TLR5 TLR9 TNF
15 12.21 IL6 NOD2 TLR2 TLR4 TLR9 TNF
16
Show member pathways
12.13 IL6 TLR2 TLR4 TLR5 TLR9 TNF
17 12.1 IL6 TLR2 TLR4 TLR5 TLR9 TNF
18
Show member pathways
12.09 IL17A IL6 TNF
19 12.07 MPO TLR2 TLR4
20 12.06 TLR2 TLR4 TLR5 TLR9
21
Show member pathways
12.02 TLR2 TLR4 TLR5 TLR9
22 12 CCR3 CSF2 IL6 MPO TNF
23 11.96 IL6 TLR4 TNF
24 11.96 CSF2 IL6 NOD2 TNF
25 11.93 IL17A IL6 TNF
26 11.9 CSF2 IL6 TLR2 TLR4 TNF
27
Show member pathways
11.89 CSF2 IL17A IL6 TLR4
28 11.85 CSF2 IL6 TNF
29 11.85 CSF2 IL6 TLR4 TLR5
30 11.84 TLR2 TLR4 TLR5 TLR9
31 11.77 CSF2 IL6 TLR9 TNF
32 11.74 IL6 TLR4 TNF
33
Show member pathways
11.69 IL17A IL6 TLR2 TLR4 TLR5 TLR9
34 11.68 CCR3 CSF2 IL6 TNF
35
Show member pathways
11.66 CSF2 IL6 TNF
36 11.59 CSF2 IL17A IL6 TLR2 TLR4 TNF
37 11.53 CSF2 IL6 TNF
38 11.52 IL6 MPO TNF
39 11.52 TLR2 TLR4 TNF
40 11.51 IL6 TLR2 TLR4 TLR5 TNF
41 11.41 IL6 TLR2 TLR4 TLR9 TNF
42 11.37 IL6 TLR9 TNF
43 11.37 IL6 TLR4 TNF
44 11.33 IL17A IL6 TNF
45 11.29 CSF2 IL6 TNF
46 11.25 IL6 TLR2 TLR4 TLR5 TLR9 TNF
47 11.2 CSF2 IL17A IL6 TNF
48
Show member pathways
11.18 IL17A IL6 TLR2 TLR4 TLR5 TLR9
49 11.07 NOD2 TNF
50 11.05 IL6 TNF

GO Terms for Ileitis

Biological processes related to Ileitis according to GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.95 MPO NOD2 TLR4 TLR5 TLR9 TNF
2 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.93 NOD2 TLR4 TLR9 TNF
3 cellular response to lipopolysaccharide GO:0071222 9.92 CSF2 IL6 TLR4 TLR5 TNF
4 defense response GO:0006952 9.88 MPO NOD2 TNF
5 activation of MAPK activity GO:0000187 9.88 NOD2 TLR4 TNF
6 defense response to Gram-positive bacterium GO:0050830 9.87 IL6 TLR2 TNF
7 positive regulation of JNK cascade GO:0046330 9.87 NOD2 TLR4 TLR9 TNF
8 defense response to Gram-negative bacterium GO:0050829 9.86 IL6 TLR4 TLR9
9 inflammatory response GO:0006954 9.86 CCR3 IL17A IL6 TLR2 TLR4 TLR5
10 regulation of inflammatory response GO:0050727 9.85 NOD2 TLR4 TNF
11 positive regulation of inflammatory response GO:0050729 9.85 TLR2 TLR4 TLR9
12 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.85 IL6 NOD2 TLR2 TLR4 TLR9 TNF
13 positive regulation of tumor necrosis factor production GO:0032760 9.84 NOD2 TLR2 TLR4 TLR9
14 positive regulation of B cell activation GO:0050871 9.83 IL6 NOD2 TLR9
15 toll-like receptor signaling pathway GO:0002224 9.81 TLR2 TLR4 TLR9
16 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.81 TLR2 TLR4 TLR5 TLR9
17 positive regulation of nitric oxide biosynthetic process GO:0045429 9.8 TLR4 TLR5 TNF
18 lipopolysaccharide-mediated signaling pathway GO:0031663 9.79 TLR2 TLR4 TNF
19 negative regulation of interleukin-6 production GO:0032715 9.78 TLR4 TLR9 TNF
20 positive regulation of interferon-beta production GO:0032728 9.77 TLR2 TLR4 TLR9
21 positive regulation of interleukin-12 production GO:0032735 9.77 TLR2 TLR4 TLR9
22 positive regulation of interleukin-10 production GO:0032733 9.76 NOD2 TLR2 TLR4 TLR9
23 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.75 IL17A NOD2 TLR4
24 I-kappaB phosphorylation GO:0007252 9.73 TLR2 TLR4 TLR9
25 positive regulation of NF-kappaB import into nucleus GO:0042346 9.73 TLR2 TLR4 TLR9 TNF
26 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.71 NOD2 TNF
27 positive regulation of interleukin-1 beta secretion GO:0050718 9.71 NOD2 TLR4
28 positive regulation of osteoclast differentiation GO:0045672 9.71 IL17A TNF
29 positive regulation of stress-activated MAPK cascade GO:0032874 9.71 NOD2 TLR4
30 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.71 NOD2 TLR2 TLR4 TLR9
31 negative regulation of growth of symbiont in host GO:0044130 9.7 MPO TNF
32 response to molecule of bacterial origin GO:0002237 9.7 TLR2 TLR9
33 positive regulation of podosome assembly GO:0071803 9.7 CSF2 TNF
34 maintenance of gastrointestinal epithelium GO:0030277 9.69 NOD2 TLR9
35 cellular response to lipoteichoic acid GO:0071223 9.69 TLR2 TLR4
36 macrophage activation GO:0042116 9.68 CSF2 TLR4
37 negative regulation of lipid storage GO:0010888 9.68 IL6 TNF
38 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.68 TLR4 TNF
39 positive regulation of interferon-beta biosynthetic process GO:0045359 9.67 TLR4 TLR9
40 positive regulation of toll-like receptor signaling pathway GO:0034123 9.67 TLR2 TLR5 TLR9
41 positive regulation of interleukin-23 production GO:0032747 9.65 CSF2 IL17A
42 positive regulation of interleukin-18 production GO:0032741 9.65 TLR2 TLR9
43 tumor necrosis factor production GO:0032640 9.64 TLR2 TLR9
44 cytokine secretion involved in immune response GO:0002374 9.62 NOD2 TLR2
45 regulation of cytokine secretion GO:0050707 9.62 TLR2 TLR4 TLR5 TLR9
46 positive regulation of chemokine production GO:0032722 9.55 IL6 TLR2 TLR4 TLR9 TNF
47 positive regulation of interleukin-6 production GO:0032755 9.43 IL6 NOD2 TLR2 TLR4 TLR9 TNF
48 positive regulation of interleukin-8 production GO:0032757 9.1 NOD2 TLR2 TLR4 TLR5 TLR9 TNF
49 positive regulation of transcription by RNA polymerase II GO:0045944 10.16 IL17A IL6 NOD2 TLR2 TLR4 TLR9
50 innate immune response GO:0045087 10.06 NOD2 TLR2 TLR4 TLR5 TLR9

Molecular functions related to Ileitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 9.26 TLR5 TLR9
2 cytokine activity GO:0005125 9.26 CSF2 IL17A IL6 TNF
3 peptidoglycan binding GO:0042834 9.16 NOD2 TLR2
4 lipopolysaccharide receptor activity GO:0001875 8.62 TLR2 TLR4

Sources for Ileitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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