MCID: IMG001
MIFTS: 34

Image Syndrome malady

Endocrine diseases category

Summaries for Image Syndrome

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19GeneReviews, 32MalaCards
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MalaCards: Image Syndrome, also known as intrauterine growth restriction, is related to metaphyseal dysplasia and pre-eclampsia. An important gene associated with Image Syndrome is CDKN1C (cyclin-dependent kinase inhibitor 1C (p57, Kip2)), and among its related pathways are Cell cycle and DNA Damage. The compound 5-aza-2deoxycytidine have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and bone.

GeneReviews summary for image

Aliases & Classifications for Image Syndrome

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19GeneReviews, 20GeneTests, 22GTR, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases


Aliases & Descriptions:

image syndrome 19 20
intrauterine growth restriction 19 22
intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 60
adrenal hypoplasia congenita,genital anomalies 19
metaphyseal dysplasia 19


Related Diseases for Image Syndrome

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17GeneCards, 18GeneDecks
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Diseases related to Image Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1metaphyseal dysplasia11.0
2pre-eclampsia10.8
3eclampsia10.8
4placental insufficiency10.6
5oligohydramnios10.5
6ulna metaphyseal dysplasia syndrome10.5
7thrombophilia10.4
8spondylo-megaepiphyseal-metaphyseal dysplasia10.4
9hellp syndrome10.4
10metaphyseal dysplasia without hypotrichosis10.4
11gastroschisis10.3
12hypospadias10.3
13hypertension10.3
14craniometaphyseal dysplasia10.3
15metaphyseal dysplasia with maxillary hypoplasia with or without brachydactyly10.3
16metaphyseal dysplasia, braun-tinschert type10.3
17lissencephaly10.3
18microcephaly10.3
19gestational diabetes10.3
20polyhydramnios10.3
21congenital heart defect10.3
22thyroiditis10.3
23schmid metaphyseal chondrodysplasia10.2
24mckusick type metaphyseal dysplasia10.2
25pancreatitis10.2
26dwarfism10.2
27verloes van maldergem marneffe syndrome10.2
28metaphyseal dysplasia maxillary hypoplasia brachydactyly10.2
29multiple joint dislocations metaphyseal dysplasia10.2
30cartilage-hair hypoplasia10.1
31osteopetrosis10.1
32brachydactyly10.1
33exocrine pancreatic insufficiency10.1
34spondyloepimetaphyseal dysplasia, missouri type10.1
35jansen's metaphyseal chondrodysplasia10.1
36schwachman diamond type metaphyseal dysplasia10.1
37optic atrophy10.1
38metaphyseal anadysplasia10.1
39autoimmune polyendocrinopathy syndrome , type i, with or without reversible metaphyseal dysplasia10.1
40silver-russell syndrome10.1
41generalized anxiety disorder10.1
42cystadenoma10.1
43major depressive disorder10.1
44pulmonary immaturity10.1
45twin-to-twin transfusion syndrome10.1
46polydactyly10.1
47glucose intolerance10.1
48adult syndrome10.1
49holoprosencephaly10.1
50anxiety disorder10.1

Graphical network of the top 20 diseases related to Image Syndrome:



Diseases related to image syndrome

Clinical Features for Image Syndrome

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Drugs & Therapeutics for Image Syndrome

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Image Syndrome

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Genetic Tests for Image Syndrome

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20GeneTests, 22GTR
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Genetic tests related to Image Syndrome:

id Genetic test Affiliating Genes
1 Image Syndrome20 CDKN1C
2 Intrauterine Growth Restriction22

Anatomical Context for Image Syndrome

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32MalaCards
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MalaCards organs/tissues related to Image Syndrome:

32
Brain, Heart, Bone, Lung, Kidney, Skin, Ovary, Adrenal gland, Testes, Pituitary, Liver, Colon, Spinal cord, Eye, Amygdala, Thalamus, Olfactory bulb, Temporal lobe, Fetal brain, Cervix, Testis, Uterus, Lymph node, Breast, Small intestine, Thyroid, Pancreas, Bone marrow

Animal Models for Image Syndrome or affiliated genes

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Publications for Image Syndrome

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Sources:
50PubMed
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Articles related to Image Syndrome:

(show top 50)    (show all 903)
idTitleAuthorsYear
1
Langer-Giedion syndrome: the evolving imaging features in hands and beyond. (24072254)
2014
2
Multiple small hyperintense lesions in the subcortical white matter on cranial MR images in two Turkish brothers with cold-induced sweating syndrome caused by a novel missense mutation in the CRLF1 gene. (23026229)
2013
3
Simpson-Golabi-Behmel syndrome diagnosed by postmortem magnetic resonance imaging, restricted autopsy, and molecular genetics: a case report. (24169032)
2013
4
Hypertrophic olivary degeneration on magnetic resonance imaging in mitochondrial syndromes associated with POLG and SURF1 mutations. (22729384)
2013
5
3T diffusion tensor imaging and electroneurography of peripheral nerve: A morphofunctional analysis in carpal tunnel syndrome. (23870213)
2013
6
Radiographic and clinical outcome of syringomyelia in patients treated for tethered cord syndrome without other significant imaging abnormalities. (23259548)
2013
7
Pre- and post-operative diffusion tensor imaging of the median nerve in carpal tunnel syndrome. (22318509)
2012
8
Multispectral diagnostic imaging of the iris in pigment dispersion syndrome. (21423031)
2012
9
Hypereosinophilic syndrome with cardiac involvement: early diagnosis by cardiac magnetic resonance imaging. (22381909)
2012
10
Images in clinical medicine. Ectopic Cushing's syndrome. (22188007)
2011
11
Prenatal magnetic resonance imaging diagnosis of molar tooth sign at 17 to 18 weeks of gestation in two fetuses at risk for Joubert syndrome and related cerebellar disorders. (21500139)
2011
12
Blue rubber bleb nevus syndrome: imaging of small bowel lesions with peroral CT enterography. (21085955)
2011
13
The prevalence of superior canal dehiscence syndrome as assessed by temporal bone computed tomography imaging. (21142747)
2011
14
Imaging evidence for renomegaly in patients with POEMS syndrome. (21782480)
2011
15
Investigation of suspected Guillain-Barre syndrome in childhood: What is the role for gadolinium enhanced magnetic resonance imaging of the spine? (20626577)
2010
16
A rare case of hypoplastic left heart syndrome and scimitar syndrome: value of neonatal cardiac magnetic resonance imaging. (20195854)
2010
17
Imaging Keratitis-Icthyosis-Deafness (KID) syndrome with FDG-PET (F18-fluorodeoxiglucose-Positron Emission Tomography). (22470741)
2010
18
3 Tesla magnetic resonance imaging with and without corticotropin releasing hormone stimulation for the detection of microadenomas in Cushing's syndrome. (19811509)
2010
19
A child with Cushing's syndrome--etiological clue from adrenal imaging (pediatric Cushing's syndrome). (21714455)
2010
20
High-resolution spectral domain optical coherence tomography images of AlstrAPm syndrome. (21158358)
2010
21
Medical image. Duodenal transposition for superior mesenteric artery syndrome in a child. (19966881)
2009
22
Clinical utility of cardiac magnetic resonance imaging in Churg-Strauss syndrome: case report and review of the literature. (18802704)
2009
23
Heterogeneity of magnetic resonance imaging in Leigh syndrome with SURF1 gene 604G-->C mutation. (19135921)
2009
24
123I-ADAM SPECT imaging of serotonin transporter binding in patients with night eating syndrome: a preliminary report. (18281200)
2008
25
Superior vena cava syndrome in a child and venous collateral pathways: MDCT imaging. (18670312)
2008
26
Imaging of Horner's syndrome. (18374711)
2008
27
Selective cerebral volume reduction in Rett syndrome: a multiple-approach MR imaging study. (18065507)
2008
28
Clinical challenges and images in GI. Klippel-Trenaunay syndrome. (18485903)
2008
29
Contribution of fetal MR imaging in the prenatal diagnosis of Zellweger syndrome. (16484405)
2006
30
Progressive non-infectious anterior vertebral fusion (Copenhagen Syndrome) in three children: features on radiographs and MR imaging. (16328382)
2006
31
Perfusion and diffusion tensor imaging in a patient with locked-in syndrome after neurosurgical vascular bypass and endovascular embolization of a basilar artery aneurysm: case report. (16575301)
2006
32
Diffusion-weighted magnetic resonance imaging in the syndrome of acute bilateral basal ganglia lesions in diabetic uremia. (16700013)
2006
33
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. (16908579)
2006
34
MRI image on hyperperfusion syndrome following aorto-bicarotid and aorto-biaxillary bypass for Takayasu's arteritis. (16194606)
2005
35
Images in clinical medicine. Stevens-Johnson syndrome. (15843672)
2005
36
Role of dopamine transporter imaging in investigation of parkinsonian syndromes in routine clinical practice. (14531041)
2003
37
Images in clinical medicine. Cardiac tamponade in Dressler's syndrome. (12789012)
2003
38
Diagnostic management of patients with SAPHO syndrome: use of MR imaging to guide bone biopsy at CT for microbiological and histological work-up. (14534805)
2003
39
Persistent MA1llerian duct syndrome suggested by magnetic resonance imaging. (14743902)
2003
40
Acute traumatic central cord syndrome: magnetic resonance imaging and clinical observations. (11795711)
2002
41
Image of the month. Esophageal perforation (Boerhaave syndrome). (11231862)
2001
42
Images in Cardiovascular Medicine. Scimitar syndrome. (9769313)
1998
43
Image of the month. CREST syndrome: calcinosis cutis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasis. (9178667)
1997
44
Special imaging casebook. Walker-Warburg syndrome. (9210086)
1997
45
Diagnostic imaging of idiopathic adult respiratory distress syndrome (ARDS)/diffuse alveolar damage (DAD) histopathological correlation with radiological imaging. (8846301)
1996
46
Markham rotation of the electron microscopic images of cilia as an accessory method in differential diagnosis between Kartagener syndrome and Sturgess syndrome. (8878622)
1996
47
Wolfram syndrome: evidence of a diffuse neurodegenerative disease by magnetic resonance imaging. (1603350)
1992
48
Magnetic resonance imaging in Mayer-Rokitansky-KA1ster-Hauser syndrome. (2145530)
1990
49
Failure of gallium-67 citrate imaging to diagnose post-myocardial infarction (Dressler's) syndrome. (3474147)
1987
50
Magnetic resonance imaging in patients with hypoplastic right heart syndrome. (4013974)
1985

Genetic Variations for Image Syndrome

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Expression for genes affiliated with Image Syndrome

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Image Syndrome

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Pathways for genes affiliated with Image Syndrome

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29KEGG, 37NCBI BioSystems Database, 4Cell Signaling Technology, 53Reactome
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Pathways related to Image Syndrome according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.0PCNA
2
Hide members
9.1PCNA, CDKN1C
3
Hide members
9.1PCNA, CDKN1C

Compounds for genes affiliated with Image Syndrome

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44Novoseek
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Compounds related to Image Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
15-aza-2deoxycytidine449.1PCNA, CDKN1C

GO Terms for genes affiliated with Image Syndrome

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Products for genes affiliated with Image Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Image Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet