MCID: IMM067

Immunodeficiency 7, Tcr-Alpha/beta Deficient malady

Immune diseases category

Summaries for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Sources:
46OMIM, 32MalaCards
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MalaCards: Immunodeficiency 7, Tcr-Alpha/beta Deficient is related to multiple sclerosis and burkitt's lymphoma. An important gene associated with Immunodeficiency 7, Tcr-Alpha/beta Deficient is TRAC (T cell receptor alpha constant), and among its related pathways are Immune response T cell receptor signaling pathway and Immune response IL-12-induced IFN-gamma production.

Description from OMIM:46 615387

Aliases & Classifications for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Sources:
46OMIM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Immune diseases


Aliases & Descriptions:

immunodeficiency 7, tcr-alpha/beta deficient 46


Related Diseases for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Immunodeficiency 7, Tcr-Alpha/beta Deficient via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1multiple sclerosis10.0TRA
2burkitt's lymphoma10.0TRAC, TRA

Clinical Features for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Sources:
46OMIM
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Clinical features from OMIM:

615387

Clinical synopsis from OMIM:

615387

Drugs & Therapeutics for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Immunodeficiency 7, Tcr-Alpha/beta Deficient

Drug clinical trials:

Search ClinicalTrials for Immunodeficiency 7, Tcr-Alpha/beta Deficient

Search NIH Clinical Center for Immunodeficiency 7, Tcr-Alpha/beta Deficient

Search CenterWatch for Immunodeficiency 7, Tcr-Alpha/beta Deficient

Genetic Tests for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Anatomical Context for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Animal Models for Immunodeficiency 7, Tcr-Alpha/beta Deficient or affiliated genes

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Publications for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Genetic Variations for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Expression for genes affiliated with Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Immunodeficiency 7, Tcr-Alpha/beta Deficient

Search GEO for disease gene expression data for Immunodeficiency 7, Tcr-Alpha/beta Deficient.

Pathways for genes affiliated with Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Sources:
12EMD Millipore
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Pathways related to Immunodeficiency 7, Tcr-Alpha/beta Deficient according to GeneCards/GeneDecks:

(show all 15)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1TRAC, TRA
29.1TRAC, TRA
3
Immune response ICOS pathway in T-helper cell
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9.1TRA, TRAC
49.1TRAC, TRA
5
Signal transduction IP3 signaling
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9.1TRAC, TRA
6
Immune response NFAT in immune response
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9.1TRAC, TRA
79.1TRAC, TRA
89.1TRA, TRAC
99.1TRAC, TRA
10
G-protein signaling Regulation of RAC1 activity
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9.1TRAC, TRA
119.1TRA, TRAC
129.1TRAC, TRA
139.1TRA, TRAC
149.1TRAC, TRA
15
Immune response Antigen presentation by MHC class II
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9.1TRAC, TRA

Compounds for genes affiliated with Immunodeficiency 7, Tcr-Alpha/beta Deficient

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GO Terms for genes affiliated with Immunodeficiency 7, Tcr-Alpha/beta Deficient

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Products for genes affiliated with Immunodeficiency 7, Tcr-Alpha/beta Deficient

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Immunodeficiency 7, Tcr-Alpha/beta Deficient

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet