IPSID
MCID: IMM054
MIFTS: 30

Immunoproliferative Small Intestinal Disease (IPSID) malady

Cancer diseases, Gastrointestinal diseases, Immune diseases categories

Summaries for Immunoproliferative Small Intestinal Disease

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63Wikipedia, 32MalaCards
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Wikipedia:63 Immunoproliferative disorders (also known as “immunoproliferative diseases” or... more...

MalaCards: Immunoproliferative Small Intestinal Disease, also known as mediterranean lymphoma, is related to sarcoma and intestinal disease. An important gene associated with Immunoproliferative Small Intestinal Disease is TP53 (tumor protein p53), and among its related pathways are Selected targets of p53 and Wnt Signaling Pathway. The compounds cyclophosphamide and vincristine have been mentioned in the context of this disorder. Affiliated tissues include small intestine, nk cells and t cells, and related mouse phenotype reproductive system.

Aliases & Classifications for Immunoproliferative Small Intestinal Disease

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Sources:
48Orphanet, 60UMLS, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 35MESH via Orphanet, 26ICD10 via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Gastrointestinal diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

48
immunoproliferative small intestinal disease:
Inheritance: Sporadic; Age of onset: Adulthood; Age of death: Adult


Aliases & Descriptions:

immunoproliferative small intestinal disease 48 60
mediterranean lymphoma 48
ipsid 48


External Ids:

SNOMED-CT via Orphanet57 109982002, 109985000, 123313007 27461004, more
UMLS via Orphanet61 C0021071
MESH via Orphanet35 D007161
ICD10 via Orphanet26 C88.3
ICD1025 C88.3

Related Diseases for Immunoproliferative Small Intestinal Disease

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Immunoproliferative Small Intestinal Disease:



Diseases related to immunoproliferative small intestinal disease

Clinical Features for Immunoproliferative Small Intestinal Disease

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Drugs & Therapeutics for Immunoproliferative Small Intestinal Disease

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Immunoproliferative Small Intestinal Disease

Drug clinical trials:

Search ClinicalTrials for Immunoproliferative Small Intestinal Disease

Search NIH Clinical Center for Immunoproliferative Small Intestinal Disease

Search CenterWatch for Immunoproliferative Small Intestinal Disease

Genetic Tests for Immunoproliferative Small Intestinal Disease

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Anatomical Context for Immunoproliferative Small Intestinal Disease

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Sources:
32MalaCards
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MalaCards organs/tissues related to Immunoproliferative Small Intestinal Disease:

32
Small intestine, Nk cells, T cells, B cells

Animal Models for Immunoproliferative Small Intestinal Disease or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Immunoproliferative Small Intestinal Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053899.9TP53

Publications for Immunoproliferative Small Intestinal Disease

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Genetic Variations for Immunoproliferative Small Intestinal Disease

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Expression for genes affiliated with Immunoproliferative Small Intestinal Disease

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Immunoproliferative Small Intestinal Disease

Search GEO for disease gene expression data for Immunoproliferative Small Intestinal Disease.

Pathways for genes affiliated with Immunoproliferative Small Intestinal Disease

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Sources:
12EMD Millipore, 37NCBI BioSystems Database, 29KEGG
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Pathways related to Immunoproliferative Small Intestinal Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3BCL6, TP53
2
Hide members
9.3BCL6, TP53
39.3TP53, BCL6
49.3TP53, BCL6
59.0SDC1, TP53

Compounds for genes affiliated with Immunoproliferative Small Intestinal Disease

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank
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Compounds related to Immunoproliferative Small Intestinal Disease according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1cyclophosphamide44 49 1111.3TP53, BCL6
2vincristine44 49 1111.0TP53, BCL6

GO Terms for genes affiliated with Immunoproliferative Small Intestinal Disease

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Sources:
16Gene Ontology
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Cellular components related to Immunoproliferative Small Intestinal Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein complexGO:0432349.0SDC1, TP53
2replication forkGO:0056579.0TP53, BCL6

Biological processes related to Immunoproliferative Small Intestinal Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein import into nucleus, translocationGO:0000609.3TP53, BCL6
2positive regulation of apoptotic processGO:0430659.3TP53, BCL6
3negative regulation of cell growthGO:0303089.2TP53, BCL6
4response to DNA damage stimulusGO:0069749.0TP53, BCL6

Molecular functions related to Immunoproliferative Small Intestinal Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chromatin bindingGO:0036829.3TP53, BCL6

Products for genes affiliated with Immunoproliferative Small Intestinal Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Immunoproliferative Small Intestinal Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet