Aliases & Classifications for Impetigo

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Impetigo, Aliases & Descriptions:

Name: Impetigo 9 11 32 3 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


External Ids:

Disease Ontology9 DOID:8504
ICD9CM27 684
MeSH33 D007169
ICD1025 L01, L01.0

Summaries for Impetigo

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MedlinePlus:32 Impetigo is a skin infection caused by bacteria. it is usually caused by staphylococcal (staph) bacteria, but it can also be caused by streptococcal (strep) bacteria. it is most common in children between the ages of two and six. it usually starts when bacteria get into a break in the skin, such as a cut, scratch, or insect bite. symptoms start with red or pimple-like sores surrounded by red skin. these sores can be anywhere, but usually they occur on your face, arms and legs. the sores fill with pus, then break open after a few days and form a thick crust. they are often itchy, but scratching them can spread the sores. impetigo can spread by contact with sores or nasal discharge from an infected person. you can treat impetigo with antibiotics. nih: national institute of allergy and infectious diseases

MalaCards based summary: Impetigo is related to hypersensitivity syndrome, carbamazepine-induced and dermatitis. An important gene associated with Impetigo is DSG1 (desmoglein 1), and among its related pathways are Prostaglandin Synthesis and Regulation and Endothelin. The compounds [125i]et-1 and pd 145065 have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related mouse phenotypes are integument and hematopoietic system.

Disease Ontology:9 A pyoderma consisting of three forms of skin lesions having either a thick, adherent, recurrent, dirty yellow crust with an erythematous margin (common or superficial impetigo) or lessions which are superficial, thin-walled, and bullous as found in bullous impetigo. the lesions in bullous (staphylococcal) impetigo, which are always caused by s aureus, are superficial, thin-walled, and bullous.

CDC:3 Group A Streptococcus (group A strep, GAS) bacteria can live in a person's nose and throat. The bacteria are spread through contact with droplets from an infected person's cough or sneeze. If you touch your mouth, nose, or eyes after touching something that has these droplets on it, you may become ill. If you drink from the same glass or eat from the same plate as the sick person, you could also become ill. It is also possible for group A strep bacteria to spread from contact with sores from a group A strep skin infection.

Wikipedia:63 Impetigo /?mp??ta??o?/ is a highly contagious bacterial skin infection most common among pre-school... more...

Related Diseases for Impetigo

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Diseases related to Impetigo via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 113)
idRelated DiseaseScoreTop Affiliating Genes
1hypersensitivity syndrome, carbamazepine-induced30.9DSG1, EDNRA, EDNRB
2dermatitis30.7CD79A, DSG3, DSG1
3pemphigus vegetans30.7DSG1
4ritter's disease30.7DSG1, EDNRA, EDNRB
5glomerulonephritis30.5EDNRB, CD79A, CD40LG
6pemphigus30.4DSG4, DSG1, DSG3, CD79A
7acute poststreptococcal glomerulonephritis30.3CD79A, SKA2, EDNRB
8pemphigus foliaceus30.2DSG1, DSG3, CD79A
9meningitis29.7SUMF2, CD79A
10pneumonia29.6EDNRA, PI3, SUMF2, CD79A
11impetigo herpetiformis10.9
12erysipelas10.5PI3
13netherton syndrome10.5DSG1
14hepatopulmonary syndrome10.5EDNRB
15exfoliation syndrome10.4EDNRB, EDNRA
16bullous skin disease10.4DSG3, DSG1
17cystic kidney10.4EDNRA, EDNRB
18atopic dermatitis10.4
19psoriasis10.4
20impotence10.4EDNRB, EDNRA
21q fever10.3CD79A
22polycystic kidney disease, autosomal dominant10.3EDNRB, EDNRA
23pharyngitis10.3
24scabies10.3
25blindness10.3
26syphilis10.3CD79A
27macroglobulinemia10.3CD79A
28cryptosporidiosis10.3CD79A
29sinusitis10.2CD79A
30hypoparathyroidism10.2
31miliaria10.2
32pemphigus vulgaris10.2DSG4, DSG1, DSG3
33pulmonary hypertension10.2EDNRA, EDNRB
34subcorneal pustular dermatosis10.2CD79A, DSG1
35ecthyma10.2
36miliaria rubra10.2
37herpes simplex10.2
38pyoderma10.2
39systemic scleroderma10.2EDNRB, EDNRA, CD40LG
40epidermolysis bullosa acquisita10.1DSG1, CD79A
41tonsillitis10.1EDNRA, CD79A
42mucoepidermoid carcinoma10.1NR4A1, SUMF2
43alopecia10.1
44carbuncle10.1
45conjunctivitis10.1
46dermatitis herpetiformis10.1
47exfoliative dermatitis10.1
48nephritis10.1
49congenital toxoplasmosis10.1CD40LG, CD79A
50immunoglobulin g deficiency10.1CD40LG, CD79A

Graphical network of the top 20 diseases related to Impetigo:



Diseases related to impetigo

Symptoms for Impetigo

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Drugs & Therapeutics for Impetigo

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Drug clinical trials:

Search ClinicalTrials for Impetigo

Search NIH Clinical Center for Impetigo

Genetic Tests for Impetigo

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Anatomical Context for Impetigo

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MalaCards organs/tissues related to Impetigo:

31
Skin, Eye

Animal Models for Impetigo or affiliated genes

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MGI Mouse Phenotypes related to Impetigo:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.5CD40LG, NR4A1, DSG3, DSG4, EDNRB
2MP:00053977.3EDNRA, DSG4, DSG3, FARSA, NR4A1, CD79A
3MP:00107687.2EDNRB, EDNRA, DSG4, DSG3, FARSA, NR4A1
4MP:00053877.2CD40LG, EDNRB, EDNRA, DSG4, DSG3, FARSA

Publications for Impetigo

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Articles related to Impetigo:

(show top 50)    (show all 432)
idTitleAuthorsYear
1
Clinical inquiry: what is the best treatment for impetigo ? (25061625)
2014
2
Value of serum procalcitonin and interleukin-6 in patients with bullous impetigo and staphylococcal scalded skin syndrome. (25298068)
2014
3
Treatment of impetigo in resource-limited settings. (25172375)
2014
4
The microbiology of impetigo in Indigenous children: associations between Streptococcus pyogenes , Staphylococcus aureus, scabies, and nasal carriage. (25551178)
2014
5
Outbreak of bullous impetigo caused by Staphylococcus aureus strains of phage type 3C/71 in a maternity ward linked to nasal carriage of a healthcare worker. (22378195)
2012
6
Treatment of impetigo: oral antibiotics most commonly prescribed. (22453587)
2012
7
Impetigo presenting as an acute necrotizing swelling of the lower lip in an adult patient. (22677026)
2012
8
First trimester impetigo herpetiformis in multiparous female successfully treated with oral cyclosporine. (22696729)
2011
9
Trimethopim-sulfamethoxazole compared with benzathine penicillin for treatment of impetigo in Aboriginal children: a pilot randomised controlled trial. (20415992)
2010
10
Topical therapies for impetigo. (20216288)
2010
11
Efficacy and safety of retapamulin ointment as treatment of impetigo: randomized double-blind multicentre placebo-controlled trial. (18341664)
2008
12
Information from your family doctor. Impetigo: what you should know. (17390598)
2007
13
Diagnosis and treatment of impetigo. (17390597)
2007
14
Is blistering distal dactylitis a variant of bullous impetigo? (17362240)
2007
15
A retrospective study of some clinical and epidemiological features of impetigo patients seen in dermatology clinic in the eastern province of saudi arabia. (23012100)
2006
16
Methotrexate treatment of recurrent impetigo herpetiformis with hypoparathyroidism. (16836512)
2006
17
Topical antibiotic treatment of impetigo with tetracycline. (16361729)
2005
18
Current options for the treatment of impetigo in children. (16218885)
2005
19
Impetigo herpetiformis--a rare dermatosis of pregnancy associated with prenatal complications. (16284679)
2005
20
Antimicrobial resistance of Staphylococcus aureus isolated from impetigo patients between 1994 and 2000. (12581136)
2003
21
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. (12093888)
2002
22
Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1. (11062541)
2000
23
Paediatric dermatology. Impetigo. (9735496)
1998
24
Streptococcal impetigo among aboriginal children in Malaysia. (9139400)
1995
25
Twin sisters with impetigo herpetiformis. (8903778)
1995
26
Double-blind study comparing erythromycin and mupirocin for treatment of impetigo in children: implications of a high prevalence of erythromycin-resistant Staphylococcus aureus strains. (1605593)
1992
27
Impetigo. (1899777)
1991
28
Increasing the antibiotic spectrum in the treatment of impetigo. (2305732)
1990
29
Two sisters with impetigo herpetiformis. (2805396)
1989
30
Diagnosis and treatment of impetigo. (2913075)
1989
31
Treatment of impetigo and ecthyma. A comparison of sulconazole with miconazole. (3069760)
1988
32
Impetigo contagiosa: a comparison of erythromycin and dicloxacillin therapy. (3045781)
1988
33
Bullous impetigo and localized scalded skin syndrome in the elderly. (3623889)
1987
34
Incidence of circulating immune complexes in patients with acute poststreptococcal glomerulonephritis and in patients with streptococcal impetigo. (3530567)
1986
35
Topical antibiotic treatment of impetigo with mupirocin. (3096221)
1986
36
What histologic finding distinguishes superficial pemphigus and bullous impetigo? (6375421)
1984
37
Some aspects of impetigo herpetiformis. (7059209)
1982
38
Sequential bullous impetigo and cutaneous Herpes simplex virus infection. (6761658)
1982
39
A comparative study of Fucidin Ointment and Cicatrin Cream in the treatment of impetigo. (7028065)
1981
40
Bullous impetigo caused by Streptococcus salivarius: a case report. (7002959)
1980
41
Letter: Telephoners' impetigo. (952547)
1976
42
Haemolysin and enzyme patterns of coagulase-positive staphylococci isolated from toxic epidermal necrolysis, Ritter's disease and impetigo contagiosa. (4252396)
1969
43
Impetigo herpetiformis in two successive pregnancies. (4286099)
1966
44
Three cases of acute nephritis occurring simultaneously in a family following impetigo contagiosa. (14392361)
1955
45
Impetigo and acute infectious exfoliative dermatitis of the newborn infant (Ritter's disease). (14955740)
1952
46
On impetigo herpetiformis. (14822640)
1951
47
Chronic symmetric impetigo. (18110559)
1949
48
Impetigo Herpetiformis.A ? Pemphigus Vegetans. (20917911)
1947
49
Impetigo bullosa in the tropics. (21065466)
1945
50
Bullous Purpura following Impetigo. (19973963)
1909

Variations for Impetigo

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Expression for genes affiliated with Impetigo

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Search GEO for disease gene expression data for Impetigo.

Pathways for genes affiliated with Impetigo

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Pathways related to Impetigo according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9EDNRA, EDNRB
29.9EDNRA, EDNRB
39.9EDNRA, EDNRB
4
Show member pathways
9.8DSG3, DSG1
59.7CD79A, CD40LG

Compounds for genes affiliated with Impetigo

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Compounds related to Impetigo according to GeneCards Suite gene sharing:

(show top 50)    (show all 69)
idCompoundScoreTop Affiliating Genes
1[125i]et-12810.3EDNRB, EDNRA
2pd 1450654310.3EDNRB, EDNRA
3sitaxsentan43 2811.3EDNRB, EDNRA
4bq6104310.3EDNRB, EDNRA
5pd 1428934310.3EDNRB, EDNRA
6bq 302043 2811.3EDNRB, EDNRA
7ambrisentan43 2811.3EDNRB, EDNRA
8irl 162043 2811.3EDNRB, EDNRA
9fr13931743 2811.3EDNRB, EDNRA
10sarafotoxin4310.3EDNRB, EDNRA
11darusentan43 2811.3EDNRB, EDNRA
12atrasentan4310.3EDNRA, EDNRB
13tezosentan4310.3EDNRA, EDNRB
14bq78843 2811.2EDNRA, EDNRB
15bq12343 2811.2EDNRA, EDNRB
16bosentan43 1211.2EDNRB, EDNRA
17sulfolipid i4310.1CD79A, CD40LG
18sandoglobulin4310.1CD79A, CD40LG
19gamma globulin4310.0CD79A, CD40LG
20vancomycin43 1210.9CD79A, CD40LG
21pneumococcal439.9CD40LG, CD79A
22blys439.9CD40LG, CD79A
23sulfonamide439.9EDNRA, EDNRB
24tuberculin439.9CD40LG, CD79A
25praziquantel43 1210.8CD40LG, CD79A
26hemocyanin439.8CD79A, CD40LG
27rituximab43 49 1211.8CD40LG, CD79A, DSG1
28gliadin439.8CD40LG, CD79A
29prednisolone43 28 1211.6CD79A, DSG3, EDNRA
30toxin a439.6DSG3, DSG1, EDNRA, EDNRB
31pmma439.6CD40LG, CD79A
32formaldehyde43 2410.6EDNRA, CD79A, CD40LG
33indomethacin43 28 59 1212.5CD40LG, CD79A, EDNRA, EDNRB
34norepinephrine43 24 1211.5CD40LG, CD79A, EDNRA, EDNRB
35pge2439.4CD40LG, CD79A, EDNRA, EDNRB
36histamine43 28 2411.4EDNRA, PI3, CD79A, CD40LG
37ivig439.4DSG1, DSG3, CD79A, CD40LG
38silicone439.4CD40LG, CD79A
39dopamine43 28 24 1212.2EDNRA, NR4A1, CD79A, CD40LG
40steroid439.1EDNRB, EDNRA, PI3, NR4A1, CD79A
41vegf438.9EDNRB, EDNRA, NR4A1, CD79A, CD40LG
42alanine438.9EDNRB, EDNRA, NR4A1, CD79A, CD40LG
43testosterone43 59 24 1211.9EDNRA, NR4A1, CD79A, CD40LG
44acetylcholine43 49 28 24 1212.8EDNRB, EDNRA, DSG1, DSG3, CD79A, CD40LG
45retinoic acid43 249.7EDNRB, PI3, DSG1, NR4A1, CD79A, CD40LG
46cyclosporin a43 28 5910.7EDNRB, EDNRA, PI3, NR4A1, CD79A, CD40LG
47dexamethasone43 49 28 1211.7EDNRB, EDNRA, PI3, NR4A1, CD79A, CD40LG
48cysteine438.7EDNRB, EDNRA, PI3, NR4A1, CD79A, CD40LG
49calcium43 49 24 1211.4EDNRB, EDNRA, PI3, DSG4, DSG1, DSG3
50serine438.4EDNRB, EDNRA, PI3, DSG1, DSG3, NR4A1

GO Terms for genes affiliated with Impetigo

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Cellular components related to Impetigo according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1desmosomeGO:00300579.1DSG3, DSG1, DSG4
2plasma membraneGO:00058868.0EDNRA, DSG4, DSG1, DSG3, CD79A, CD40LG

Biological processes related to Impetigo according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1regulation of epithelial cell proliferationGO:005067810.0EDNRA, EDNRB
2vasoconstrictionGO:004231010.0EDNRA, EDNRB
3enteric nervous system developmentGO:00484849.9EDNRB, EDNRA
4sensory perception of painGO:00192339.9EDNRA, EDNRB
5B cell proliferationGO:00421009.6CD40LG, CD79A
6homophilic cell adhesionGO:00071569.5DSG3, DSG1, DSG4
7cellular component disassembly involved in execution phase of apoptosisGO:00069219.5DSG3, DSG1

Molecular functions related to Impetigo according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endothelin receptor activityGO:00049629.9EDNRA, EDNRB

Products for genes affiliated with Impetigo

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Sources for Impetigo

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