MCID: IMP006
MIFTS: 43

Impulse Control Disorder

Categories: Mental diseases

Aliases & Classifications for Impulse Control Disorder

MalaCards integrated aliases for Impulse Control Disorder:

Name: Impulse Control Disorder 12 14
Disruptive, Impulse Control, and Conduct Disorders 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10937
ICD10 32 F63.9
ICD9CM 34 312.30
MeSH 41 D007174
NCIt 46 C34723
UMLS 69 C0021122

Summaries for Impulse Control Disorder

Disease Ontology : 12 A disease of mental health that involves a failure to resist an impulsive act or behaviour that may be harmful to self or others.

MalaCards based summary : Impulse Control Disorder, also known as disruptive, impulse control, and conduct disorders, is related to trichotillomania and pathological gambling. An important gene associated with Impulse Control Disorder is ANKK1 (Ankyrin Repeat And Kinase Domain Containing 1), and among its related pathways/superpathways are Dopamine-DARPP32 Feedback onto cAMP Pathway and Circadian rythm related genes. The drugs Carbidopa and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include brain, skin and testes, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 72 Impulse-control disorder (ICD) is a class of psychiatric disorders characterized by impulsivity –... more...

Related Diseases for Impulse Control Disorder

Diseases related to Impulse Control Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 trichotillomania 32.0 CLNK DLGAP3 SLITRK1
2 pathological gambling 31.2 DRD2 DRD3 DRD4
3 alexithymia 29.7 ANKK1 DRD2
4 gilles de la tourette syndrome 29.4 DRD2 DRD4 SLITRK1
5 parkinson disease, late-onset 28.9 DRD2 DRD3 DRD4
6 disease of mental health 28.6 DRD2 DRD3 DRD4 GRN
7 obsessive-compulsive disorder 28.3 DLGAP3 DRD2 DRD3 DRD4 SLITRK1
8 kleptomania 11.3
9 pyromania 11.1
10 intermittent explosive disorder 10.9
11 kluver-bucy syndrome 10.9
12 stereotypic movement disorder 10.2 CLNK SLITRK1
13 taqi polymorphism 10.2 ANKK1 DRD2
14 follicular mucinosis 10.2 DLGAP3 SLITRK1
15 antisocial personality disorder 10.1 ANKK1 DRD2
16 oppositional defiant disorder 10.1 DRD2 DRD4
17 restless legs syndrome 10.0
18 heroin dependence 10.0 ANKK1 DRD2 DRD4
19 tic disorder 9.9 DRD2 DRD4 SLITRK1
20 conduct disorder 9.9 DRD2 DRD4
21 pituitary adenoma, prolactin-secreting 9.8
22 polysubstance abuse 9.8 DRD2 DRD3
23 tardive dyskinesia 9.8 DRD2 DRD3
24 supranuclear palsy, progressive, 1 9.7 DRD2 GRN
25 perry syndrome 9.7
26 dystonia 3, torsion, x-linked 9.7
27 alacrima, achalasia, and mental retardation syndrome 9.7
28 bipolar disorder 9.7
29 burns 9.7
30 withdrawal disorder 9.7
31 paraphilia disorder 9.7
32 basal ganglia calcification 9.7
33 stuttering 9.7
34 social phobia 9.7
35 premature ejaculation 9.7
36 bipolar i disorder 9.7
37 epilepsy 9.7
38 dermatitis 9.7
39 dystonia 9.7
40 rem sleep behavior disorder 9.7
41 opiate dependence 9.7 DRD2 DRD3
42 cocaine dependence 9.6 DRD2 DRD3
43 drug dependence 9.6 ANKK1 DRD2 DRD3
44 delusional disorder 9.6 DRD2 DRD3 DRD4
45 early-onset schizophrenia 9.6 DRD2 DRD3 DRD4
46 migraine without aura 9.6 DRD2 DRD3 DRD4
47 personality disorder 9.5 DRD2 DRD3 DRD4
48 substance abuse 9.5 DRD2 DRD3 DRD4
49 substance dependence 9.5 DRD2 DRD3 DRD4
50 psychotic disorder 9.5 DRD2 DRD3 DRD4

Comorbidity relations with Impulse Control Disorder via Phenotypic Disease Network (PDN):


Schizophreniform Disorder

Graphical network of the top 20 diseases related to Impulse Control Disorder:



Diseases related to Impulse Control Disorder

Symptoms & Phenotypes for Impulse Control Disorder

GenomeRNAi Phenotypes related to Impulse Control Disorder according to GeneCards Suite gene sharing:

25 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.6 DRD4
2 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.6 DRD4
3 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.6 CLNK DRD3 DRD4
4 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.6 DRD3
5 Increased shRNA abundance (Z-score > 2) GR00366-A-158 9.6 CLNK
6 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.6 DRD3
7 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.6 DRD3
8 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.6 DRD3
9 Increased shRNA abundance (Z-score > 2) GR00366-A-172 9.6 DRD4
10 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.6 CLNK
11 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.6 DRD3
12 Increased shRNA abundance (Z-score > 2) GR00366-A-51 9.6 DRD3
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.6 CLNK
14 Increased shRNA abundance (Z-score > 2) GR00366-A-56 9.6 DRD4
15 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.6 DRD3
16 Increased shRNA abundance (Z-score > 2) GR00366-A-8 9.6 CLNK
17 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.6 DRD3

MGI Mouse Phenotypes related to Impulse Control Disorder:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.17 CGA DLGAP3 DRD2 DRD3 DRD4 GRN

Drugs & Therapeutics for Impulse Control Disorder

Drugs for Impulse Control Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 71)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carbidopa Approved Phase 4 28860-95-9 38101 34359
2
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
3
Levodopa Approved Phase 4 59-92-7 6047
4
Methylphenidate Approved, Investigational Phase 4 20748-11-2, 113-45-1 4158
5
Nicotine Approved Phase 4 54-11-5 89594 942
6
Topiramate Approved Phase 4 97240-79-4 5284627
7
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 16590-41-3 5360515
8
Pramipexole Approved, Investigational Phase 4 104632-26-0 119570 59868
9
Ropinirole Approved, Investigational Phase 4 91374-20-8, 91374-21-9 5095 497540
10
Sertraline Approved Phase 4 79617-96-2 68617
11
Citalopram Approved Phase 4 59729-33-8 2771
12
Acamprosate Approved, Investigational Phase 4 77337-76-9 71158
13
Ethanol Approved Phase 4 64-17-5 702
14
Selegiline Approved, Investigational, Vet_approved Phase 4 14611-51-9 5195 26757
15 Antiparkinson Agents Phase 4,Phase 3
16 Aromatic Amino Acid Decarboxylase Inhibitors Phase 4
17 Autonomic Agents Phase 4,Phase 3
18 Dopamine Agents Phase 4,Phase 3,Phase 2
19 Dopamine agonists Phase 4,Phase 3,Phase 2
20 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
21 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
22 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
23 Central Nervous System Stimulants Phase 4
24 Dopamine Uptake Inhibitors Phase 4
25 Neurotransmitter Uptake Inhibitors Phase 4
26 Cholinergic Agents Phase 4
27 Nicotinic Agonists Phase 4
28 Anticonvulsants Phase 4
29 Anti-Obesity Agents Phase 4
30 Neuroprotective Agents Phase 4
31 Narcotic Antagonists Phase 4,Phase 3,Phase 2
32 Narcotics Phase 4,Phase 3,Phase 2
33 Antidepressive Agents Phase 4
34 Psychotropic Drugs Phase 4,Phase 3
35
Serotonin Phase 4,Phase 3 50-67-9 5202
36 Serotonin Agents Phase 4,Phase 3
37 Serotonin Uptake Inhibitors Phase 4
38 Antidepressive Agents, Second-Generation Phase 4
39 Cholinergic Antagonists Phase 4
40 Muscarinic Antagonists Phase 4
41 Parasympatholytics Phase 4
42 Monoamine Oxidase Inhibitors Phase 4
43
Risperidone Approved, Investigational Phase 3 106266-06-2 5073
44
Acetylcysteine Approved, Investigational Phase 3,Phase 2,Phase 1 616-91-1 12035
45
Cabergoline Approved Phase 3 81409-90-7 54746
46 Antipsychotic Agents Phase 3
47 Central Nervous System Depressants Phase 3
48 Dopamine Antagonists Phase 3
49 Serotonin Antagonists Phase 3
50 Tranquilizing Agents Phase 3

Interventional clinical trials:

(show all 33)

# Name Status NCT ID Phase Drugs
1 Remission of ICD by Switching Dopamine Agonist to Levodopa/Carbidopa Unknown status NCT01683253 Phase 4 Levodopa/Carbidopa(200mg/50mg)
2 Methylphenidate in ADHD With Trichotillomania Unknown status NCT00552266 Phase 4 Methylphenidate
3 Nicotine Treatment of Impulsivity in Parkinson's Disease Unknown status NCT01216904 Phase 4 nicotine patch;placebo
4 Topiramate in the Treatment of Pathological Gambling Unknown status NCT00245583 Phase 4 topiramate (Topomax)
5 Naltrexone for Impulse Control Disorders in Parkinson's Disease Completed NCT01052831 Phase 4 Naltrexone;Placebo
6 Sertraline and Habit Reversal in the Treatment of Patients With Trichotillomania Completed NCT00118014 Phase 4 Sertraline
7 Escitalopram for the Treatment of Self-Injurious Skin Picking Completed NCT00115011 Phase 4 Escitalopram
8 Acamprosate in the Treatment of Pathological Gambling Completed NCT00571103 Phase 4 acamprosate
9 Efficacy of Orally Disintegrating Selegiline in Parkinson's Patients Experiencing Adverse Effects With Dopamine Agonists Completed NCT00443872 Phase 4 orally disintegrating selegiline (Zelapar)
10 Drug Treatment for Pathologic Gambling Disorder Completed NCT00053677 Phase 3 Naltrexone;Placebo
11 Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone. Completed NCT00399698 Phase 3 Risperdal
12 Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas Recruiting NCT02288962 Phase 3 cabergoline
13 Study of the Efficacy of N-acetylcysteine (NAC) on Impulse Control Disorders (TCI) Induced by Dopaminergic Treatments in Parkinson's Disease Not yet recruiting NCT03146130 Phase 3
14 Testing a New Therapy for Trichotillomania Unknown status NCT00872742 Phase 2
15 Double-Blind Naltrexone in Compulsive Sexual Behavior Completed NCT00467558 Phase 2 Naltrexone;Sugar pill
16 Imaging Non-motor Symptoms of Parkinson's Disease by Novel 18F-DTBZ and Florbetapir F-18 PET Completed NCT02039024 Phase 2 18F- DTBZ
17 N-Acetyl Cysteine in Pathologic Skin Picking Completed NCT01063348 Phase 2 N-Acetyl Cysteine;Placebo
18 Inositol in Trichotillomania Completed NCT01875445 Phase 2 Inositol;Placebo
19 The Use of Rotigotine for Treatment of Reducing Signs and Symptoms of Fibromyalgia in Adults. Completed NCT00464737 Phase 2 Rotigotine;Rotigotine
20 Investigating the Microstructural and Functional Alterations of Brain in Parkinson's Disease Patients Recruiting NCT02599753 Phase 2 18-FDTBZ
21 Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label Study Not yet recruiting NCT02934919 Phase 2 Nalmefene
22 Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement Completed NCT01039454 Phase 1 GSK598809 Capsules;GSK598809 Placebo Capsules
23 Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in Adolescents Completed NCT01111734 Phase 1 fMRI
24 Mental Health Related to School Dropout in Luxembourg Unknown status NCT01354236
25 Impulse Control Disorders in Parkinson's Patients Treated With Pramipexole and Other Agents (DOMINION Study) Completed NCT00617019
26 Behavioural Addiction and Genetics in Parkinson's Disease Completed NCT02319395
27 Exploration of Mesocorticolimbic Pathway in Impulse Control Disorders in Parkinson's Disease: Study Using Tensor Diffusion Imaging and Tractography. Recruiting NCT02796040
28 Fingerprinting of Impulsivity Recruiting NCT02722174
29 fMRI in Impulsivity Recruiting NCT02755181
30 Exploration of the Reward System by Functional MRI in Narco-cataplexy Patients With and Without REM Sleep Behavior Disorder Recruiting NCT03425214
31 Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder Recruiting NCT02824341
32 Effects of Non-invasive Brain Stimulation in Impulse Control Disorders Active, not recruiting NCT02927002
33 Psychiatric and Cognitive Manifestations of Parkinson's Disease Enrolling by invitation NCT00360633

Search NIH Clinical Center for Impulse Control Disorder

Cochrane evidence based reviews: disruptive, impulse control, and conduct disorders

Genetic Tests for Impulse Control Disorder

Anatomical Context for Impulse Control Disorder

MalaCards organs/tissues related to Impulse Control Disorder:

38
Brain, Skin, Testes, Pituitary, Prefrontal Cortex, Liver, Cortex

Publications for Impulse Control Disorder

Articles related to Impulse Control Disorder:

(show top 50) (show all 68)
# Title Authors Year
1
Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias. ( 29198499 )
2018
2
Sleep and REM sleep behaviour disorder in Parkinson's disease with impulse control disorder. ( 29066517 )
2017
3
Risk of Gambling Disorder and Impulse Control Disorder With Aripiprazole, Pramipexole, and Ropinirole: A Pharmacoepidemiologic Study. ( 27930495 )
2017
4
Depression, Impulse Control Disorder, and Life Style According to Smartphone Addiction. ( 29295357 )
2017
5
ISMP Adverse Drug Reactions: Pregabalin-Induced Stuttering Nitroglycerine-Induced Bradycardia Progressing to Asystole Minocycline-Induced DRESS Leading to Liver Transplantation and Type 1 Diabetes Increased Risk of Vertebral Fractures in Women Receiving Thiazide or Loop Diuretics Gambling Disorder and Impulse Control Disorder with Aripiprazole. ( 28515502 )
2017
6
Recurrent Impulse Control Disorder Associated with Rasagiline Treatment of Parkinson's Disease. ( 28767029 )
2017
7
Electro-acupuncture treatment for internet addiction: Evidence of normalization of impulse control disorder in adolescents. ( 28861803 )
2017
8
Impulse control disorder and response-inhibition alterations in Parkinson's disease. A rare case of totally absent functionality of the medial-prefrontal cortex and review of literature. ( 29034115 )
2017
9
Cabergoline-related impulse control disorder in an adolescent with a giant prolactinoma. ( 28346715 )
2017
10
Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism. ( 27997702 )
2017
11
A Multicenter Comparative Study of Impulse Control Disorder in Latin American Patients With Parkinson Disease. ( 28288482 )
2017
12
Impulse control disorder related behaviours during long-term rotigotine treatment: a post hoc analysis. ( 27425586 )
2016
13
Tattooing as a Symptom of Impulse Control Disorder in a Parkinsonian Patient With Pramipexole. ( 27749676 )
2016
14
Psychosis and concurrent impulse control disorder in Parkinson's disease: A review based on a case report. ( 29213446 )
2016
15
Association between REM sleep behaviour disorder and impulse control disorder in patients with Parkinson's disease. ( 27087472 )
2016
16
Repetitive urges to inflict burns: An unusual presentation of impulse control disorder. ( 28163418 )
2016
17
Impulse control disorder in PD: A lateralized monoaminergic frontostriatal disconnection syndrome? ( 27264342 )
2016
18
18F-FDG -PET Correlates of Impulse Control Disorder In A Diabetic Patient. ( 27697074 )
2016
19
Impaired learning of punishments in Parkinson's disease with and without impulse control disorder. ( 27848033 )
2016
20
Editorial: Exploring Gender and Sex Differences in Behavioral Dyscontrol: From Drug Addiction to Impulse Control Disorders. ( 26941657 )
2016
21
The addiction-related gene ANKK1 in Parkinsonian patients with impulse control disorder. ( 25447970 )
2015
22
Pet killing as a manifestation of impulse control disorder secondary to pramipexol. ( 25768852 )
2015
23
Idiopathic Basal Ganglia Calcification Presented with Impulse Control Disorder. ( 26246920 )
2015
24
Impulse control disorder manifesting as hidden sexual self-injury. ( 25828732 )
2015
25
Incident impulse control disorder symptoms and dopamine transporter imaging in Parkinson disease. ( 26534930 )
2015
26
Parkinson's disease treatment may cause impulse-control disorder via dopamine D3 receptors. ( 25645960 )
2015
27
[A^A^C]-(+)-PHNO PET imaging of dopamine D(2/3) receptors in Parkinson's disease with impulse control disorders. ( 25641350 )
2015
28
Impulse control disorders and punding in Perry syndrome. ( 26411500 )
2015
29
Impulse control disorder and rapid eye movement sleep behavior disorder in Parkinson's disease. ( 25283069 )
2014
30
Impulse control disorder in patients with Parkinson's disease under dopamine agonist therapy: a multicentre study. ( 24434037 )
2014
31
Amantadine and cognitive flexibility: decision making in Parkinson's patients with severe pathological gambling and other impulse control disorders. ( 24971012 )
2014
32
Depression and impulse control disorders in Parkinson's disease: Two sides of the same coin? ( 24239733 )
2014
33
REM sleep behavior disorder: association with motor complications and impulse control disorders in Parkinson's disease. ( 25085747 )
2014
34
Dopamine agonist withdrawal syndrome in a patient with restless legs syndrome without impulse control disorder or drug abuse. ( 25362251 )
2014
35
Major depression after withdrawing dopamine agonists in two patients with restless legs syndrome and impulse control disorders. ( 23714418 )
2013
36
Three cases of impulse control disorder in Parkinson's disease patients receiving dopamine replacement therapy. ( 23472375 )
2013
37
Impulse control disorder in a patient on long-term treatment with bromocriptine for a macroprolactinoma. ( 24045609 )
2013
38
Dopamine agonist-induced impulse control disorders in a patient with prolactinoma. ( 23261076 )
2013
39
Dopaminergic influences on executive function and impulsive behaviour in impulse control disorders in Parkinson's disease. ( 23901888 )
2013
40
The role of self-awareness and cognitive dysfunction in Parkinson's disease with and without impulse-control disorder. ( 23686032 )
2013
41
Pathological generosity: An atypical impulse control disorder after a left subcortical stroke. ( 23962063 )
2013
42
Impulse control disorder in a patient with X-linked dystonia-parkinsonism after bilateral pallidal deep brain stimulation. ( 23920134 )
2013
43
Is premature ejaculation an impulse control disorder? ( 22543077 )
2012
44
Transdermal rotigotine causes impulse control disorders in patients with restless legs syndrome. ( 22030321 )
2012
45
Impulse-control disorders in gilles de la tourette syndrome. ( 22450610 )
2012
46
Zoophilia and impulse control disorder in a patient with Parkinson disease. ( 22057400 )
2012
47
Role of genetic polymorphisms of the dopaminergic system in Parkinson's disease patients with impulse control disorders. ( 22113132 )
2012
48
Comorbid impulse control disorder in bipolar disorder: the role of antidepressants. ( 22423377 )
2012
49
Prevalence and pharmacological factors associated with impulse-control disorder symptoms in patients with Parkinson disease. ( 23123689 )
2012
50
Alexithymia is associated with impulsivity in newly-diagnosed, drug-naA^ve patients with Parkinson's disease: an affective risk factor for the development of impulse-control disorders? ( 23224478 )
2012

Variations for Impulse Control Disorder

Expression for Impulse Control Disorder

Search GEO for disease gene expression data for Impulse Control Disorder.

Pathways for Impulse Control Disorder

GO Terms for Impulse Control Disorder

Cellular components related to Impulse Control Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endocytic vesicle GO:0030139 8.62 DRD2 DRD3

Biological processes related to Impulse Control Disorder according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 synapse assembly GO:0007416 9.65 DRD2 SLITRK1
2 negative regulation of protein kinase B signaling GO:0051898 9.65 DRD2 DRD3
3 circadian regulation of gene expression GO:0032922 9.65 DRD2 DRD3
4 negative regulation of adenylate cyclase activity GO:0007194 9.65 DRD2 DRD3 DRD4
5 social behavior GO:0035176 9.64 DRD3 DRD4
6 visual learning GO:0008542 9.64 DRD2 DRD3
7 response to cocaine GO:0042220 9.63 DRD2 DRD3
8 positive regulation of cytokinesis GO:0032467 9.63 DRD2 DRD3
9 negative regulation of blood pressure GO:0045776 9.62 DRD2 DRD3
10 response to morphine GO:0043278 9.62 DRD2 DRD3
11 adult behavior GO:0030534 9.61 DRD2 SLITRK1
12 regulation of dopamine secretion GO:0014059 9.61 DRD2 DRD3
13 response to amphetamine GO:0001975 9.61 DRD2 DRD3 DRD4
14 synaptic transmission, dopaminergic GO:0001963 9.6 DRD2 DRD3
15 behavioral response to ethanol GO:0048149 9.59 DRD2 DRD4
16 negative regulation of voltage-gated calcium channel activity GO:1901386 9.58 DRD2 DRD4
17 prepulse inhibition GO:0060134 9.58 DRD2 DRD3
18 arachidonic acid secretion GO:0050482 9.58 DRD2 DRD3 DRD4
19 positive regulation of renal sodium excretion GO:0035815 9.57 DRD2 DRD3
20 G-protein coupled receptor internalization GO:0002031 9.56 DRD2 DRD3
21 regulation of cAMP metabolic process GO:0030814 9.55 DRD2 DRD3
22 regulation of dopamine uptake involved in synaptic transmission GO:0051584 9.54 DRD2 DRD3
23 behavioral response to cocaine GO:0048148 9.54 DRD2 DRD3 DRD4
24 positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 9.52 DRD2 DRD4
25 negative regulation of dopamine receptor signaling pathway GO:0060160 9.51 DRD2 DRD3
26 dopamine receptor signaling pathway GO:0007212 9.5 DRD2 DRD3 DRD4
27 acid secretion GO:0046717 9.49 DRD2 DRD3
28 regulation of locomotion involved in locomotory behavior GO:0090325 9.46 DRD2 DRD3
29 negative regulation of protein secretion GO:0050709 9.43 DRD2 DRD3 DRD4
30 dopamine metabolic process GO:0042417 9.33 DRD2 DRD3 DRD4
31 adenylate cyclase-inhibiting dopamine receptor signaling pathway GO:0007195 9.13 DRD2 DRD3 DRD4
32 response to histamine GO:0034776 8.8 DRD2 DRD3 DRD4

Molecular functions related to Impulse Control Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.43 DRD2 DRD3 DRD4
2 dopamine binding GO:0035240 9.33 DRD2 DRD3 DRD4
3 dopamine neurotransmitter receptor activity, coupled via Gi/Go GO:0001591 9.13 DRD2 DRD3 DRD4
4 dopamine neurotransmitter receptor activity GO:0004952 8.8 DRD2 DRD3 DRD4

Sources for Impulse Control Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
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47 NDF-RT
50 NINDS
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53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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