IBM
MCID: INC002
MIFTS: 66

Inclusion Body Myositis (IBM) malady

Categories: Genetic diseases, Rare diseases, Neuronal diseases, Bone diseases, Metabolic diseases, Blood diseases, Muscle diseases

Aliases & Classifications for Inclusion Body Myositis

About this section
Sources:
11Disease Ontology, 13DISEASES, 24GeneTests, 25Genetics Home Reference, 27GTR, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 40MESH via Orphanet, 45NCIt, 48NIH Rare Diseases, 49NINDS, 50Novoseek, 52OMIM, 54Orphanet, 62SNOMED-CT, 64The Human Phenotype Ontology, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Inclusion Body Myositis:

Name: Inclusion Body Myositis 52 11 48 49 54 27 13 68
Nonaka Myopathy 11 48 25 54 68
Distal Myopathy with Rimmed Vacuoles 11 48 25 54
Ibm2 11 48 25 54
Inclusion Body Myopathy, Autosomal Recessive 48 25 68
Hereditary Inclusion Body Myopathy 11 48 25
Inclusion Body Myopathy 2 11 48 25
Inclusion Body Myopathy 3 11 48 24
Dmrv 48 25 54
Hibm 11 48 25
Inclusion Body Myopathy, Quadriceps-Sparing 48 25
Sporadic Inclusion Body Myositis 54 50
Inclusion Body Myopathy Type 2 54 27
Distal Myopathy, Nonaka Type 11 54
Rimmed Vacuole Myopathy 48 25
Gne Myopathy 48 54
Ibm3 48 24
Ibm 48 54
Qsm 48 25
 
Myopathy with Congenital Joint Contractures, Ophthalmoplegia, and Rimmed Vacuoles 48
Hereditary Inclusion Body Myopathy - Joint Contractures - Ophthalmoplegia 48
Inclusion Body Myopathy, Autosomal Dominant 68
Inclusion Body Myopathy Autosomal Dominant 48
Hereditary Inclusion Body Myopathy Type 3 48
Hereditary Inclusion Body Myopathy Type 2 54
Inclusion Body Myopathy, Sporadic 68
Inclusion Body Myopathy Type 3 27
Quadriceps Sparing Myopathy 48
Quadriceps-Sparing Myopathy 54
Myositis, Inclusion Body 39
Inflammatory Myopathies 49
Myositis Inclusion Body 50
Inflammatory Myopathy 48
Myositis 68
Hibm2 54
Ibm-3 11
Hibm3 48
Sibm 54

Characteristics:

Orphanet epidemiological data:

54
inclusion body myositis:
Inheritance: Not applicable; Prevalence: 1-9/1000000 (Europe); Age of onset: Adult; Age of death: normal life expectancy
nonaka myopathy:
Inheritance: Autosomal recessive; Prevalence: 6-9/10000; Age of onset: Adolescent,Adult,Elderly

HPO:

64
inclusion body myositis:
Inheritance: autosomal dominant inheritance, sporadic
Onset and clinical course: slow progression, phenotypic variability

Classifications:



External Ids:

OMIM52 147421
Disease Ontology11 DOID:3429
ICD1030 G72.41
ICD9CM32 359.71
MeSH39 D018979
SNOMED-CT62 72315009
NCIt45 C84786
Orphanet54 ORPHA611, ORPHA602
UMLS via Orphanet69 C0238190
ICD10 via Orphanet31 M60.8, G71.8
MESH via Orphanet40 C536816

Summaries for Inclusion Body Myositis

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NINDS:49 Inclusion body myositis (IBM) is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic, progressive muscle inflammation accompanied by muscle weakness.  The onset of muscle weakness in IBM is generally gradual (over months or years) and affects both proximal (close to the trunk of the body) and distal (further away from the trunk) muscles.  Muscle weakness may affect only one side of the body.  Falling and tripping are usually the first noticeable symptoms of IBM.  For some individuals, the disorder begins with weakness in the wrists and fingers that causes difficulty with pinching, buttoning, and gripping objects.  There may be weakness of the wrist and finger muscles and atrophy (thinning or loss of muscle bulk) of the forearm muscles and quadricep muscles in the legs.  Difficulty swallowing occurs in approximately half of IBM cases.  Symptoms of the disease usually begin after the age of 50, although the disease can occur earlier.  IBM occurs more frequently in men than in women.

MalaCards based summary: Inclusion Body Myositis, also known as nonaka myopathy, is related to inclusion body myopathy, autosomal recessive and hereditary inclusion body myopathy type 4, and has symptoms including back pain, muscle cramp and muscle rigidity. An important gene associated with Inclusion Body Myositis is GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase), and among its related pathways are Josephin domain DUBs and Apoptosis-related network due to altered Notch3 in ovarian cancer. The drugs chlorzoxazone and tizanidine hydrochloride have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, t cells and bone, and related mouse phenotypes are immune system and muscle.

NIH Rare Diseases:48 Inclusion body myopathy 2, also known as hereditary inclusion body myopathy (hibm), gne-related myopathy,  distal myopathy with rimmed vacuoles, and nonaka myopathy, is an inherited condition that primarily affects the skeletal muscles (the muscles that the body uses to move). this disorder is characterized by muscle weakness that appears in late adolescence or early adulthood and worsens over time. early symptoms typically develop in the 20s and 30s and may include difficulty running or walking, tripping, weakness in the index finger, and frequent loss of balance. inclusion body myopathy 2 is caused by mutations in the gne gene. the condition is inherited in an autosomal recessive manner. treatment is focused on managing individual symptoms. last updated: 1/13/2014

Genetics Home Reference:25 Inclusion body myopathy 2 is a condition that primarily affects skeletal muscles, which are muscles that the body uses for movement. This disorder causes muscle weakness that appears in late adolescence or early adulthood and worsens over time.

OMIM:52 Sporadic inclusion body myositis (IBM) is the most common age-related muscle disease in the elderly that results in... (147421) more...

Disease Ontology:11 A myositis that is characterized by slowly progressive weakness and wasting of both distal and proximal muscles, most apparent in the muscles of the arms and legs that can occur in a sporadic or hereditary forms.

Wikipedia:71 Inclusion body myositis (IBM) is an inflammatory muscle disease characterized by slowly progressive... more...

Related Diseases for Inclusion Body Myositis

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Diseases related to Inclusion Body Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1inclusion body myopathy, autosomal recessive12.2
2hereditary inclusion body myopathy type 412.1
3gne-related myopathy11.4
4polymyositis11.4
5idiopathic inflammatory myopathy11.3
6proximal myopathy and ophthalmoplegia11.2
7myositis11.1
8nonaka myopathy10.8
9myopathy10.5
10dermatomyositis10.4
11keratosis palmoplantaris striata10.4APOE, MAPT
12bone dysplasia azouz type10.3APOE, APP, MAPT
13hfe-associated hereditary hemochromatosis10.3GNE, SQSTM1
14pulmonary systemic sclerosis10.3APOE, MAPT, SERPINA3
15dysphagia10.3
16limited scleroderma10.3APOE, APP, SERPINA3
17cerebroretinal vasculopathy10.3MAPT, SQSTM1, VCP
18craniofacial and skeletal defects10.3MAPT, RPS27A, TARDBP
19meier-gorlin syndrome 510.3APOE, APP, MAPT, RPS27A
20meckel syndrome 1010.3APOE, APP, MAPT, SERPINA3
21autoimmune disease of urogenital tract10.3APOE, MAPT, TARDBP
22hypoproteinemia, hypercatabolic10.3APP, MAPT, RPS27A, TARDBP
23contagious pustular dermatitis10.3APOE, APP, MAPT, SERPINA3
24arthrogryposis multiplex congenita, distal, type 110.3GNE, SQSTM1
25adult mesenchymal chondrosarcoma10.3MAPT, TARDBP, VCP
26polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract10.3APOE, APP, BACE1, SERPINA3
27pancreatic cancer/melanoma syndrome10.3SQSTM1, TARDBP, VCP
28rippling muscle disease10.2DYSF, MSTN
29pancreatic solid pseudopapillary carcinoma10.2MAPT, SQSTM1, TARDBP, VCP
30autism 1910.2MAPT, RPS27A, SQSTM1
31adrenal cortical adenoma10.2GNE, SQSTM1, TARDBP, VCP
32coenzyme q10 deficiency, primary, 110.2APOE, APP, MAPT, RPS27A, TARDBP
33pericardial tuberculosis10.2TARDBP, VCP
34severe congenital nemaline myopathy10.2APOE, MAPT, RPS27A, TARDBP, VCP
35gallbladder adenoma10.2APP, MAPT, RPS27A
36acne inversa, familial, 310.2APOE, MAPT, RPS27A, SQSTM1, TARDBP
37andersen syndrome10.2MAPT, RPS27A, SQSTM1, TARDBP, VCP
38mucopolysaccharidosis iv10.2MAPT, RPS27A, SQSTM1, TARDBP, VCP
39angina pectoris10.2APOE, MAPT, TARDBP
40ichthyosis lamellar 210.2APOE, APP, MAPT
41eumycotic mycetoma10.1APOE, APP, MAPT, SQSTM1, TARDBP, VCP
42muscular dystrophy10.1
43substance-induced psychosis10.1APOE, APP, BACE1, CXCR3, MAPT, TARDBP
44epithelioid type angiomyolipoma10.1APOE, APP, BACE1, CXCR3, MAPT, TARDBP
45deafness, autosomal recessive 6710.1CXCL9, CXCR3, HLA-DRB1
46advanced sleep phase syndrome, familial, 110.1APOE, CXCL9, CXCR3, HLA-DRB1
47long qt syndrome 510.1APP, MAPT, RPS27A, SQSTM1, TARDBP, VCP
48cerebral angioma10.1DYSF, EMD, GNE, MSTN
49hepatitis10.1
50hepatitis c10.1

Graphical network of the top 20 diseases related to Inclusion Body Myositis:



Diseases related to inclusion body myositis

Symptoms & Phenotypes for Inclusion Body Myositis

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Symptoms by clinical synopsis from OMIM:

147421

Clinical features from OMIM:

147421

Human phenotypes related to Inclusion Body Myositis:

 54 64 (show all 43)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 reduced tendon reflexes64 54 Frequent (79-30%) HP:0001315
2 autoimmunity64 54 Very frequent (99-80%) HP:0002960
3 ragged-red muscle fibers64 54 Very frequent (99-80%) HP:0003200
4 skeletal muscle atrophy64 54 Very frequent (99-80%) HP:0003202
5 elevated serum creatine phosphokinase64 54 Very frequent (99-80%) HP:0003236
6 myalgia64 54 Occasional (29-5%) HP:0003326
7 emg abnormality64 54 Very frequent (99-80%) HP:0003457
8 proximal muscle weakness64 54 Very frequent (99-80%) HP:0003701
9 quadriceps muscle weakness64 54 Very frequent (99-80%) HP:0003731
10 rimmed vacuoles64 54 Very frequent (99-80%) HP:0003805
11 abnormality of muscle fibers54 Very frequent (99-80%)
12 feeding difficulties in infancy64 54 Frequent (79-30%) HP:0008872
13 inflammatory myopathy64 54 Very frequent (99-80%) HP:0009071
14 lower limb muscle weakness54 Very frequent (99-80%)
15 mildly elevated creatine phosphokinase64 54 Very frequent (99-80%) HP:0008180
16 tibialis muscle weakness64 54 Very frequent (99-80%) HP:0008963
17 foot dorsiflexor weakness64 54 Very frequent (99-80%) HP:0009027
18 fatty replacement of skeletal muscle64 54 Very frequent (99-80%) HP:0012548
19 muscle fiber inclusion bodies64 54 Very frequent (99-80%) HP:0100299
20 hypothyroidism64 54 Frequent (79-30%) HP:0000821
21 steppage gait64 54 Frequent (79-30%) HP:0003376
22 absent achilles reflex64 54 Frequent (79-30%) HP:0003438
23 emg: myopathic abnormalities54 Frequent (79-30%)
24 shoulder girdle muscle weakness64 54 Frequent (79-30%) HP:0003547
25 increased variability in muscle fiber diameter64 54 Frequent (79-30%) HP:0003557
26 limited wrist extension64 54 Frequent (79-30%) HP:0006251
27 limited shoulder movement64 54 Frequent (79-30%) HP:0006467
28 hip flexor weakness64 54 Frequent (79-30%) HP:0012515
29 emg: positive sharp waves54 Frequent (79-30%)
30 emg: myotonic discharges54 Frequent (79-30%)
31 muscle weakness54 Occasional (29-5%)
32 abnormality of the foot musculature54 Occasional (29-5%)
33 scapular winging64 54 Occasional (29-5%) HP:0003691
34 shoulder girdle muscle atrophy64 54 Occasional (29-5%) HP:0003724
35 lower limb amyotrophy64 54 Occasional (29-5%) HP:0007210
36 facial palsy64 54 Occasional (29-5%) HP:0010628
37 abnormality of the right hemidiaphragm64 54 Occasional (29-5%) HP:0040047
38 cardiomyopathy64 54 Very rare (<4-1%) HP:0001638
39 weakness of long finger extensor muscles64 54 Very rare (<4-1%) HP:0009077
40 hyporeflexia64 HP:0001265
41 dysphagia64 HP:0002015
42 distal muscle weakness64 HP:0002460
43 emg64 HP:0003458

UMLS symptoms related to Inclusion Body Myositis:


back pain, muscle cramp, muscle rigidity, muscle spasticity, myoclonus, sciatica, torticollis, muscle weakness, myalgia, ophthalmoplegia, generalized muscle weakness

MGI Mouse Phenotypes related to Inclusion Body Myositis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053879.4APOE, APP, CXCR3, DYSF, GNE, MAPT
2MP:00053699.3APOE, APP, BACE1, DYSF, EMD, GNE
3MP:00053869.2APOE, APP, BACE1, DYSF, EMD, GNE
4MP:00030129.2APOE, APP, BACE1, DYSF, MAPT, MSTN

Drugs & Therapeutics for Inclusion Body Myositis

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Drugs for Inclusion Body Myositis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 110)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
AbataceptapprovedPhase 4, Phase 3197332348-12-610237
Synonyms:
CTLA4-Ig
 
CTLA4-IgG4m
CTLA4Ig
CTLA4IgG4m
2Immunosuppressive AgentsPhase 4, Phase 3, Phase 2, Phase 1, Early Phase 113086
3Anesthetics, LocalPhase 43492
4Antirheumatic AgentsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 110956
5AnestheticsPhase 49596
6
Memantineapproved, investigationalPhase 318119982-08-24054
Synonyms:
1,3-Dimethyl-5-adamantanamine
1-Amino-3,5-dimethyladamantane
19982-08-2
3,5-Dimethyl-1-adamantanamine
3,5-Dimethyl-1-adamantylamine
3,5-Dimethyl-1-aminoadamantane
3,5-Dimethyladamantan-1-ylamine
3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine
3,5-dimethyladamantan-1-amine
3,5-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
41100-52-1 (Hydrochloride)
51052-62-1
AB00053600
AC1L1HB7
AKOS000113995
BBL000737
BPBio1_001117
BPBio1_001270
BSPBio_001015
Biomol-NT_000209
C13736
CBMicro_020348
CHEBI:152523
CHEMBL807
CID4054
D08174
DB01043
DMAA
DivK1c_000068
EU-0053634
Ebixa
Exiba
Exiba (TN)
HMS500D10
HSDB 7327
IDI1_000068
KBio1_000068
KBio2_001087
KBio2_003655
 
KBio2_006223
KBio3_001926
KBioGR_001543
KBioSS_001087
LS-157051
Lopac0_000861
Memantin
Memantina
Memantina [INN-Spanish]
Memantine
Memantine (INN)
Memantine HCL
Memantine Hydrochloride
Memantine [INN:BAN]
Memantine [INN]
Memantinum
Memantinum [INN-Latin]
MolPort-002-041-858
NCGC00015705-05
NCGC00024782-02
NCGC00024782-03
NINDS_000068
Namenda
Oprea1_480562
Prestwick0_000978
Prestwick1_000978
Prestwick2_000978
Prestwick3_000978
SPBio_001456
SPBio_002926
ST057652
STK520682
Spectrum2_001408
Spectrum3_000923
Spectrum4_001022
Spectrum5_001355
Spectrum_000607
UNII-W8O17SJF3T
ZERO/006024
memantine
7
DopamineapprovedPhase 3383651-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
8
Prednisoneapproved, vet_approvedPhase 3139853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
9
Prednisoloneapproved, vet_approvedPhase 3119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
10
Methylprednisoloneapproved, vet_approvedPhase 3119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
11
MethotrexateapprovedPhase 315511959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
 
Methopterin
Methotextrate
Methotrate
Methotrexat
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Rheumatrex
Trexall
12
AcetaminophenapprovedPhase 2, Phase 31026103-90-21983
Synonyms:
4'-Hydroxyacetanilide
4'-hydroxyacetanilide
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
4-acetamidophenol
A-Per
A.F. Anacin
AC1Q1KYJ
AC1Q1KYK
APAP
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-Tap
Acenol
Acephen
Acertol
Aceta Elixir
Aceta Tablets
Acetaco
Acetagesic
Acetalgin
Acetaminofen
Acetaminophen
Acetaminophen Uniserts
Acetamol
Acetavance
Acetofen
Actamin
Actamin Extra
Actamin Super
Actifed Plus
Actimol
Actimol Chewable Tablets
Actimol Children'S Suspension
Actimol Infants' Suspension
Actimol Junior Strength Caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen Max
Anacin
Anacin 3
Anacin-3
Anacin-3 Extra Strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
Anhiba
Anoquan
Anti-Algos
Antidol
Anuphen
Apacet
Apacet Capsules
Apacet Elixir
Apacet Extra Strength Caplets
Apacet Extra Strength Tablets
Apacet Regular Strength Tablets
Apadon
Apamid
Apamide
Apitrelal
Apo-Acetaminophen
Arfen
Arthralgen
Asetam
Asomal
Aspac
Aspirin Free Anacin Maximum Strength Caplets
Aspirin Free Anacin Maximum Strength Gel Caplets
Aspirin Free Anacin Maximum Strength Tablets
Aspirin-Free Anacin
Aspirin-Free Excedrin Caplets
Asplin
Atasol
Atasol Caplets
Atasol Drops
Atasol Forte Caplets
Atasol Forte Tablets
Atasol Oral Solution
Atasol Tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap Hc
Banesin
Bayer Select
Bayer Select Allergy-Sinus
Bayer Select Head Cold
Bayer Select Headache Pain
Bayer Select Maximum Strength Headache Pain Relief Formula
Bayer Select Menstrual Multi-Symptom
Bayer Select Sinus Pain Relief
Ben-u-ron
Benmyo
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
CCRIS 3
CHEBI:46195
Cadafen
Calapol
Calmanticold
Calonal
Calpol
Capital
Capital with Codeine
Captin
Causalon
Cefalex
Cetadol
Children'S Acetaminophen Elixir Drops
Children'S Acetaminophen Oral Solution
Children'S Tylenol Chewable
Claradol Codeine
Clixodyne
Co-Gesic
Cod-Acamol Forte
Codabrol
Codalgin
Codapane
Codicet
Codisal
Codisal Forte
Codoliprane
Codral Pain Relief
Cofamol
Conacetol
Contac Cough & Sore Throat Formula
Contra-Schmerz P
Coricidin
Coricidin D
Coricidin Sinus
Cosutone
Croix Blanche
Cuponol
Curadon
Curpol
Custodial
D oliprane
Dafalgan
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril Extra-Strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
Dhc Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
Dol-Stop
Dolcor
Dolefin
Dolegrippin
Dolene AP-65
Dolene Ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol Forte
Dolorstop
Dolotec
Dolprone
Dorocoff
Dresan
Dristan Cold No Drowsiness
Dristancito
Drixoral Plus
Duaneo
Dularin
Duorol
Duracetamol
Duradyne Dhc
Durapan
Dymadon
Dymadon Co
Dymadon Forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-Plus
Eu-Med
Excedrin
Excedrin Caplets
Excedrin Extra Strength Caplets
Excipain
Exdol
Exdol Strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-Gesic
Febrolin
Femcet
Fendon
Fensum
Fepanil
Fever All
Feverall
Feverall Junior Strength
Feverall Sprinkle Caps Junior Strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon P
Freka-cetamol
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap Children'S Elixir
Genapap Children'S Tablets
Genapap Extra Strength Caplets
Genapap Extra Strength Tablets
Genapap Regular Strength Tablets
Genebs
Genebs Extra Strength Caplets
Genebs Regular Strength Tablets
Genebs X-Tra
Geralgine-P
Gripin Bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hy-Phen
Hycomine Compound
Hydrocet
Ildamol
Inalgex
Infadrops
Infants' Feverall
Influbene N
Injectapap
Intensin
Janupap
Jin Gang
Junior Disprol
KBio1_000660
Kataprin
Kinder Finimal
Korum
Kratofin simplex
L024125
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liqiprine
Liquagesic
Liquigesic Co
Liquiprin
Liquiprin Children'S Elixir
Liquiprin Infants" Drops
Lonarid
Lonarid Mono
Lorcet-Hd
Lortab
Lupocet
Lyteca
Lyteca Syrup
Magnidol
Malex N
Malgis
Malidens
Maxadol
Medigesic Plus
Medinol Paediatric
Medocodene
Melabon Infantil
Mexalen
Midol Maximum Strength
Midol PM Night Time Formula
Midol Regular Strength
Midol Teen Formula
Migraleve Yellow
Minafen
Minoset
Miralgin
Momentum
Mono Praecimed
 
Multin
N-(4-Hydroxyphenyl)acetamide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
N-acetyl-p-aminophenol
NAPA
NCX 701
NEBS
NSC3991
Naldegesic
Napafen
Napap
Naprinol
Nealgyl
Nebs
Neo-Fepramol
NeoCitran
Neodol
Neodolito
Neopap
Neotrend
Neuridon
New Cortal for Children
NilnOcen
Nina
No-Febril
Nobedon
Nodolex
Noral
Norcet
Norco
O-Acetaminophenol
Ofirmev
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/Apap 500
Oxycodone 5/Apap 500
PCM Paracetamol Lichtenstein
Paceco
Pacemo
Pacemol
Pacet
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine Co
Panadiene
Panado-Co
Panado-Co Caplets
Panadol
Panadol Extra Strength
Panadol Junior Strength Caplets
Panadol Maximum Strength Caplets
Panadol Maximum Strength Tablets
Panale ve
Panaleve
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-Deine #3
Papa-Deine #4
Para-Suppo
Para-Tabs
Paracemol
Paracenol
Paracet
Paracetamol
Paracetamol AL
Paracetamol Antipanin P
Paracetamol BC
Paracetamol Basics
Paracetamol DC
Paracetamol Dr. Schmidgall
Paracetamol Fecofar
Paracetamol Genericon
Paracetamol Hanseler
Paracetamol Harkley
Paracetamol Heumann
Paracetamol Hexal
Paracetamol Italfarmaco
Paracetamol Nycomed
Paracetamol PB
Paracetamol Raffo
Paracetamol Ratiopharm
Paracetamol Rosch
Paracetamol Saar
Paracetamol SmithKline Beecham
Paracetamol Stada
Paracetamol Winthrop
Paracetamol von ct
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Paracétamol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
Paramol
Paramolan
Paranox
Parapan
Parasedol
Parasin
Paraspen
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
Pe-Tam
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-Demi
Percogesic with Codeine
Perdolan Mono
Perfalgan
Phenaphen
Phenaphen Caplets
Phenaphen W/Codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin Forte
Pinex
Piramin
Pirinasol
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet World
Redutemp
Reliv
Remedol
Rhinex D-Lay Tablets
Rivalgyl
Robigesic
Robitussin Night Relief
Rockamol Plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
SK-Apap
SPBio_002836
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten Rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sine-Off Sinus Medicine Caplets
Sinedol
Sinmol
Sinubid
Snaplets-FR
Spalt N
Spalt fur die nacht
St Joseph Aspirin-Free
St Joseph Aspirin-Free for Children
St. Joseph Cold Tablets for Children
St. Joseph Fever Reducer
Stanback
Stopain
Sudafed Severe Cold Formula
Sudafed Sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-M
Synalgos-Dc-A
TYL
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol Extra Strength Caplets
Tapanol Extra Strength Tablets
Tapar
Tavist Allergy/Sinus/Headache
Tazamol
Temlo
Tempanal
Tempra
Tempra Caplets
Tempra Chewable Tablets
Tempra D.S
Tempra Drops
Tempra Syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
Tizide
Tocris-1706
Toximer P
Tralgon
Treupel N
Treupel mon
Treuphadol
Triad
Triaminic Sore Throat Formula
Triaprin
Tricoton
Tussapap
Ty lenol
Tycolet
Tylenol
Tylenol (TN)
Tylenol Allergy Sinus
Tylenol Arthritis Extended Relief
Tylenol Caplets
Tylenol Children'S Chewable Tablets
Tylenol Children'S Elixir
Tylenol Children'S Suspension Liquid
Tylenol Drops
Tylenol Elixir
Tylenol Extra Strength Adult Liquid Pain Reliever
Tylenol Extra Strength Caplets
Tylenol Extra Strength Gelcaps
Tylenol Extra Strength Tablets
Tylenol Gelcaps
Tylenol Infants Drops
Tylenol Infants" Suspension Drops
Tylenol Junior Strength Caplets
Tylenol Junior Strength Chewable Tablets
Tylenol Regular Strength Caplets
Tylenol Regular Strength Tablets
Tylenol Tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin Extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor Richet
Vicodin
Vicodin Es
Vicodin Hp
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
acetaminofén
acétaminophène
alpha-Per
p-(Acetylamino)phenol
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
p-acetamidophenol
p-acetaminophenol
p-hydroxy-acetanilid
p-hydroxyacetanilide
p-hydroxyphenolacetamide
13
DolasetronapprovedPhase 38115956-12-260654
Synonyms:
115956-12-2
3-oxooctahydro-2h-2,6-methanoquinolizin-8-yl 1h-indole-3-carboxylate
AC1L1FA2
AC1L1TNT
AC1MHWDD
AC1Q6P88
AC1Q6P89
AR-1F4842
Anzemet
BIDD:GT0287
C07866
CHEBI:253226
CHEMBL523689
CID11503972
CID3033818
 
CID3148
CID60654
D07867
DB00757
Dolasetron
Dolasetron (INN)
Dolasetron [INN:BAN]
Dolasetronum
Dolasetronum [INN-Latin]
Dolasteron
Dolasétron
HSDB 7565
LS-172300
MolPort-006-393-891
UNII-82WI2L7Q6E
dolasetron
14
PetrolatumapprovedPhase 2, Phase 3938009-03-8
Synonyms:
Multi-hydrocarbon
Paraffinum album
Paraffinum flavum
Petrolatum base
Petrolatum, white
 
Petrolatum,amber
Petrolatum,white
Petroleum jelly
Soft paraffin
White petrolatum
White, soft paraffin
Yellow soft paraffin
15
InfliximabapprovedPhase 2, Phase 3392170277-31-3
Synonyms:
 
Ig gamma-1 chain C region
Remicade
16
EverolimusapprovedPhase 2, Phase 31940159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
17
Miconazoleapproved, investigational, vet_approvedPhase 2, Phase 3370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
18
Sirolimusapproved, investigationalPhase 2, Phase 3194053123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
19
leucovorinapproved, NutraceuticalPhase 3323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
20
Folic Acidapproved, nutraceutical, vet_approvedPhase 3439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
21Dopamine AgentsPhase 33836
22Antiparkinson AgentsPhase 31574
23Excitatory Amino Acid AntagonistsPhase 31347
24Neurotransmitter AgentsPhase 3, Phase 218340
25Excitatory Amino AcidsPhase 31362
26Autonomic AgentsPhase 310150
27Prednisolone phosphatePhase 31193
28Vitamin B ComplexPhase 34337
29AntiemeticsPhase 34022
30Immunoglobulins, IntravenousPhase 3, Phase 2, Phase 1333
31Prednisolone hemisuccinatePhase 31193
32Rho(D) Immune GlobulinPhase 3, Phase 2, Phase 1326
33Anti-Bacterial AgentsPhase 2, Phase 311226
34Anti-Infective AgentsPhase 2, Phase 322062
35gamma-GlobulinsPhase 3, Phase 2, Phase 1326
36Contraceptives, OralPhase 2, Phase 31327
37
SerotoninPhase 3362750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
38Serotonin AgentsPhase 33156
39Serotonin AntagonistsPhase 31409
40Peripheral Nervous System AgentsPhase 3, Phase 2, Phase 1, Early Phase 123689
41Contraceptive AgentsPhase 2, Phase 31967
42Prednisolone acetatePhase 31193
43Pharmaceutical SolutionsPhase 2, Phase 38192
44Anti-Inflammatory AgentsPhase 3, Phase 1, Early Phase 110729
45AntimetabolitesPhase 312054
46Antibodies, MonoclonalPhase 2, Phase 34039
47Antibodies, BlockingPhase 2, Phase 330
48Dermatologic AgentsPhase 2, Phase 35806
49Gastrointestinal AgentsPhase 2, Phase 3, Phase 1, Early Phase 18402
50Interleukin 1 Receptor Antagonist ProteinPhase 2, Phase 399

Interventional clinical trials:

(show top 50)    (show all 94)
idNameStatusNCT IDPhase
1Collagenase Injection vs Percutaneous Needle Aponeurotomy for Dupuytren's DiseaseRecruitingNCT03000114Phase 4
2Abatacept in Juvenile DermatomyositisRecruitingNCT02594735Phase 4
3Randomised Controlled Trial of Memantine in FibromyalgiaUnknown statusNCT01653457Phase 3
4Effects of Sodium Nitrate on Blood Flow in Becker Muscular DystrophyUnknown statusNCT02147639Phase 2, Phase 3
5Arimoclomol in Sporadic Inclusion Body MyositisCompletedNCT00769860Phase 2, Phase 3
6Treatment With TNF Blockade, Infliximab, in Patients With MyositisCompletedNCT00443222Phase 2, Phase 3
7Anakinra in MyositisCompletedNCT01165008Phase 2, Phase 3
8Efficacy and Safety of Bimagrumab/BYM338 at 52 Weeks on Physical Function, Muscle Strength, Mobility in sIBM PatientsCompletedNCT01925209Phase 2, Phase 3
9Study of Long-term Safety, Efficacy Tolerability of BYM338 in Patients With Sporadic Inclusion Body MyositisCompletedNCT02250443Phase 2, Phase 3
10Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DMCompletedNCT00651040Phase 3
11Efficacy of Dolasetron in Patients With FibromyalgiaCompletedNCT00820326Phase 3
12Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound HealingCompletedNCT00931567Phase 2, Phase 3
13Cytokine Inhibition in Chronic Fatigue Syndrome PatientsCompletedNCT02108210Phase 2, Phase 3
14Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory MyopathyRecruitingNCT02971683Phase 3
15Study Evaluating Efficacy and Safety of Octagam 10% in Patients With Dermatomyositis (Idiopathic Inflammatory Myopathy)RecruitingNCT02728752Phase 3
16Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Sialic Acid in Patients With GNE Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM)Active, not recruitingNCT02377921Phase 3
17Rapamycine vs Placebo for the Treatment of Inclusion Body MyositisActive, not recruitingNCT02481453Phase 2, Phase 3
18An Extension Study of the Efficacy, Safety and Tolerability of BYM338 (Bimagrumab) in Patients With Sporadic Inclusion Body Myositis Who Previously Participated in the Core Study CBYM338B2203Active, not recruitingNCT02573467Phase 3
19Study to Evaluate the Safety and Efficacy of Ace-ER Tablets in Patients With GNE Myopathy or Hereditary Inclusion Body MyopathyEnrolling by invitationNCT02736188Phase 3
20A Phase 2 Study to Evaluate the Dose and Pharmacodynamic Efficacy of Sialic Acid-Extended Release (SA-ER) Tablets in Patients With GNE Myopathy or Hereditary Inclusion Body MyopathyCompletedNCT01517880Phase 2
21Intravenousimmunoglobulin (IVIg) for the Treatment of Inflammatory MyopathiesCompletedNCT00001261Phase 2
22Alemtuzumab to Treat Sporadic Inclusion Body MyositisCompletedNCT00079768Phase 2
23Topical Sodium Thiosulfate and Fractional Carbon Dioxide Laser in Treating Dermatomyositis Associated CalcinosisCompletedNCT01572844Phase 2
24Efficacy, Safety and Tolerability of BYM338 in Patients With Sporadic Inclusion Body MyositisCompletedNCT01423110Phase 2
25Prospective Studies of the Use of Self Hypnosis, Acupuncture and Osteopathic Manipulation on Muscle Tension in Children With Spastic Cerebral PalsyCompletedNCT00011024Phase 2
26Botulinum Toxin Type A (Dysport) Associated With Rehabilitation Treatment in Patients With Primary Myofascial Pain SyndromeCompletedNCT00149240Phase 2
27Rituximab for the Treatment of Refractory Inflammatory Myopathies and Refractory Myasthenia GravisCompletedNCT00774462Phase 2
28Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)CompletedNCT00106184Phase 2
29A Study to Evaluate the Safety of Aceneuramic Acid Extended Release (Ace-ER) Tablets in GNE Myopathy (GNEM) (Also Known as Hereditary Inclusion Body Myopathy (HIBM)) Patients With Severe Ambulatory ImpairmentRecruitingNCT02731690Phase 2
30An Open Label Phase 2 Study of ManNAc in Subjects With GNE MyopathyActive, not recruitingNCT02346461Phase 1, Phase 2
31An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid (ER Tablets + IR Capsules) in Patients With GNE MyopathyActive, not recruitingNCT01830972Phase 2
32Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles TendinosisActive, not recruitingNCT02330146Phase 1, Phase 2
33HOPE-Duchenne (Halt cardiomyOPathy progrEssion in Duchenne)Active, not recruitingNCT02485938Phase 1, Phase 2
34Efficacy of Sialic Acid GNE Related ThrombocytopeniaEnrolling by invitationNCT02845609Phase 2
35Study of Arimoclomol in Inclusion Body Myositis (IBM)Not yet recruitingNCT02753530Phase 2
36Treatment and Assessment of FibromyalgiaNot yet recruitingNCT02760212Phase 2
37Phase I Clinical Trial of ManNAc in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM)CompletedNCT01634750Phase 1
38Intravenous Immune Globulin to Treat Hereditary Inclusion Body MyopathyCompletedNCT00195637Phase 1
39Safety and Pharmacokinetics of Sialic Acid Tables in Patients With Hereditary Inclusion Body Myopathy (HIBM)CompletedNCT01359319Phase 1
40Pharmacokinetic Study on N-acetylneuraminic AcidCompletedNCT01236898Phase 1
41A Pilot Study of Etanercept in DermatomyositisCompletedNCT00112385Phase 1
42A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte DiseasesRecruitingNCT02639260Phase 1
43Follistatin Gene Transfer to Patients With Becker Muscular Dystrophy and Sporadic Inclusion Body MyositisActive, not recruitingNCT01519349Phase 1
44Improving Ambulatory Community Access After ParalysisActive, not recruitingNCT01570816Phase 1
45Natalizumab in Inclusion Body Myositis (IBM)Active, not recruitingNCT02483845Phase 1
46Stem Cell Transplantation in Idiopathic Inflammatory Myopathy DiseasesTerminatedNCT00278564Phase 1
47Quantitative and Functional Study of TH17 Lymphocytes in Horton's Disease (HD)Unknown statusNCT02065297
48A Case-control Study to Assess Risk of Coronary Heart Disease in Idiopathic Inflammatory MyopathyUnknown statusNCT00971828
49Natural History in CCFDN and IBM SyndromesCompletedNCT01902940
50Immune Abnormalities in Sporadic Inclusion Body MyositisCompletedNCT00030212

Search NIH Clinical Center for Inclusion Body Myositis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: myositis, inclusion body

Genetic Tests for Inclusion Body Myositis

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Genetic tests related to Inclusion Body Myositis:

id Genetic test Affiliating Genes
1 Inclusion Body Myopathy 227
2 Inclusion Body Myopathy 327 24 MYH2
3 Inclusion Body Myositis27

Anatomical Context for Inclusion Body Myositis

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MalaCards organs/tissues related to Inclusion Body Myositis:

36
Skeletal muscle, T cells, Bone, Testes, Brain, Myeloid, Endothelial

Publications for Inclusion Body Myositis

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Articles related to Inclusion Body Myositis:

(show top 50)    (show all 609)
idTitleAuthorsYear
1
Sporadic inclusion body myositis - a myodegenerative disease or an inflammatory myopathy. (28111778)
2017
2
Physical function and muscle strength in sporadic inclusion body myositis. (28187529)
2017
3
Inclusion body myositis pathogenesis: Steady progress. (28318035)
2017
4
Overlapping features of polymyositis and inclusion body myositis in HIV-infected patients. (28283597)
2017
5
Follistatin Gene Therapy for Sporadic Inclusion Body Myositis Improves Functional Outcomes. (28279643)
2017
6
Fist sign in inclusion body myositis. (28215761)
2017
7
Burden of Illness and Healthcare Resource Use in US Patients with sporadic Inclusion Body Myositis. (28493327)
2017
8
Pathomechanisms of anti-cytosolic 5'-nucleotidase 1A autoantibodies in sporadic inclusion body myositis. (28318044)
2017
9
Sarcoidosis: Is It a Possible Trigger of Inclusion Body Myositis? (28523201)
2017
10
Association study reveals novel risk loci for sporadic inclusion body myositis. (28233382)
2017
11
A Systematic Review and Meta-Analysis ofA Prevalence Studies of Sporadic Inclusion Body Myositis. (28505979)
2017
12
Immune-array Analysis in Sporadic Inclusion Body Myositis Reveals HLA-DRB1 Amino Acid Heterogeneity across the Myositis Spectrum. (28086002)
2017
13
A Case of Asymptomatic Inclusion Body Myositis. (28221303)
2017
14
Comparison of serum rAAV serotype-specific antibodies in patients with Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Inclusion Body Myositis or GNE myopathy. (28042944)
2017
15
Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis. (28330496)
2017
16
The role of p62/SQSTM1 in sporadic inclusion body myositis. (28159418)
2017
17
Cytosolic 5'-nucleotidase 1A autoantibody profile and clinical characteristics in inclusion body myositis. (28122761)
2017
18
Targeting protein homeostasis in sporadic inclusion body myositis. (27009270)
2016
19
Inclusion Body Myositis. (27922498)
2016
20
Sporadic Inclusion Body Myositis Manifesting as Isolated Muscle Weakness of the Finger Flexors Three Years after Disease Onset. (27904121)
2016
21
Efficacy of immunosuppressive treatment in a systemic lupus erythematosus patient presenting with inclusion body myositis. (27048400)
2016
22
Botulinum toxin and rehabilitation treatment in inclusion body myositis for severe oropharyngeal dysphagia. (27098244)
2016
23
Diagnostic criteria for inclusion body myositis. (27027255)
2016
24
Lagophthalmos and Ptosis in Inclusion Body Myositis. (26784549)
2016
25
A surprising case of inclusion body myositis with positive endomysial C5b-9 staining. (26659413)
2016
26
Neuromuscular ultrasound in the evaluation of inclusion body myositis. (27797863)
2016
27
Multicenter questionnaire survey for sporadic inclusion body myositis in Japan. (27821140)
2016
28
Sporadic inclusion-body myositis: Recent advances and the state of the art in 2016. (27616487)
2016
29
Sporadic inclusion body myositis: A review of recent clinical advances and current approaches to diagnosis and treatment. (26778717)
2016
30
Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis. (27131788)
2016
31
Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis. (28009083)
2016
32
A Rare Case of Sporadic Inclusion Body Myositis (s-IBM). (26894112)
2016
33
Clinical and Electrophysiological Findings in Hereditary Inclusion Body Myopathy Compared With Sporadic Inclusion Body Myositis. (27224433)
2016
34
Epidemiology of sporadic inclusion body myositis. (27541181)
2016
35
Cytotoxic T cells go awry in inclusion body myositis. (27189577)
2016
36
Rare variants in SQSTM1 and VCP genes and risk of sporadic inclusion body myositis. (27594680)
2016
37
Intramuscular dissociation of echogenicity in the triceps surae characterizes sporadic inclusion body myositis. (26706399)
2016
38
Anesthetic Considerations of Sporadic Inclusion Body Myositis in an Elderly Man With Orthopedic Trauma. (27247916)
2016
39
Hepatitis C virus infection in inclusion body myositis: A case-control study. (26683644)
2016
40
Modeling functional decline over time in sporadic inclusion body myositis. (27511790)
2016
41
Psychometric validation of a patient-reported measure of physical functioning in sporadic inclusion body myositis. (26872636)
2016
42
Erratum to: Botulinum toxin and rehabilitation treatment in inclusion body myositis for severe oropharyngeal dysphagia. (27889862)
2016
43
Sporadic inclusion body myositis misdiagnosed as idiopathic granulomatous myositis. (27692540)
2016
44
Molecular events linking cholesterol to Alzheimer's disease and inclusion body myositis in a rabbit model. (27073745)
2016
45
Mortality and Causes of Death in Patients with Sporadic Inclusion Body Myositis: Survey Study Based on the Clinical Experience of Specialists in Australia, Europe and the USA. (27854208)
2016
46
Association of inclusion body myositis with T cell large granular lymphocytic leukaemia. (26920676)
2016
47
Transforming growth factor-I^ signaling is upregulated in sporadic inclusion body myositis. (27623743)
2016
48
Development and evaluation of a standardized ELISA for the determination of autoantibodies against cN-1A (Mup44, NT5C1A) in sporadic inclusion body myositis. (27858337)
2016
49
A protocol to develop clinical guidelines for inclusion-body myositis. (26800092)
2016
50
Inclusion body myositis and anesthesia: a case series. (27185728)
2016

Variations for Inclusion Body Myositis

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Clinvar genetic disease variations for Inclusion Body Myositis:

5 (show all 16)
id Gene Variation Type Significance SNP ID Assembly Location
1GNENM_ 005476.5(GNE): c.1760T> C (p.Ile587Thr)SNVPathogenic/ Likely pathogenicrs748949603GRCh37Chr 9, 36219891: 36219891
2GNENM_ 001128227.2(GNE): c.740T> C (p.Val247Ala)SNVPathogenic/ Likely pathogenicrs779694939GRCh38Chr 9, 36236954: 36236954
3GNENM_ 005476.5(GNE): c.527A> T (p.Asp176Val)SNVPathogenicrs139425890GRCh37Chr 9, 36246117: 36246117
4GNENM_ 005476.5(GNE): c.1571C> T (p.Ala524Val)SNVPathogenicrs764698870GRCh37Chr 9, 36222836: 36222836
5GNENM_ 001128227.2(GNE): c.2228T> C (p.Met743Thr)SNVPathogenicrs28937594GRCh37Chr 9, 36217396: 36217396
6GNENM_ 001128227.2(GNE): c.1820G> A (p.Gly607Glu)SNVPathogenicrs121908625GRCh37Chr 9, 36219924: 36219924
7GNENM_ 001190383.1(GNE): c.1669G> A (p.Ala557Thr)SNVPathogenicrs121908626GRCh37Chr 9, 36218222: 36218222
8GNENM_ 005476.5(GNE): c.2086G> A (p.Val696Met)SNVPathogenic/ Likely pathogenicrs121908627GRCh37Chr 9, 36217445: 36217445
9GNENM_ 001128227.2(GNE): c.1002T> A (p.Cys334Ter)SNVPathogenicrs121908628GRCh37Chr 9, 36233990: 36233990
10GNENM_ 001128227.2(GNE): c.830G> A (p.Arg277Gln)SNVPathogenic/ Likely pathogenicrs121908629GRCh37Chr 9, 36236861: 36236861
11GNENM_ 001128227.2(GNE): c.766G> A (p.Asp256Asn)SNVPathogenicrs121908630GRCh37Chr 9, 36236925: 36236925
12GNENM_ 005476.5(GNE): c.1714G> C (p.Val572Leu)SNVPathogenicrs121908632GRCh37Chr 9, 36219937: 36219937
13GNENM_ 001128227.2(GNE): c.1000_ 1001delTGinsGT (p.Cys334Val)indelPathogenicrs121908633GRCh37Chr 9, 36233991: 36233992
14GNENM_ 001128227.2(GNE): c.1985C> T (p.Ala662Val)SNVPathogenicrs62541771GRCh37Chr 9, 36218221: 36218221
15GNENM_ 001128227.2(GNE): c.604A> G (p.Met202Val)SNVPathogenicrs121908634GRCh37Chr 9, 36246133: 36246133
16SQSTM1NM_ 003900.4(SQSTM1): c.970_ 1165delSNVPathogenicrs796051870GRCh38Chr 5, 179833783: 179833783

Expression for genes affiliated with Inclusion Body Myositis

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Search GEO for disease gene expression data for Inclusion Body Myositis.

Pathways for genes affiliated with Inclusion Body Myositis

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Pathways related to Inclusion Body Myositis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
110.1RPS27A, VCP
310.0APP, BACE1, SQSTM1
410.0APP, BACE1, MAPT
59.8APOE, APP, BACE1, MAPT
69.6APOE, APP, BACE1, MAPT, TARDBP

GO Terms for genes affiliated with Inclusion Body Myositis

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Cellular components related to Inclusion Body Myositis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endosomeGO:000576810.3APP, BACE1, DYSF, HLA-DRB1, SQSTM1
2extracellular exosomeGO:00700628.4APOE, APP, COX5A, DYSF, HLA-DRB1, ICOSLG

Biological processes related to Inclusion Body Myositis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1amyloid fibril formationGO:199000010.8APP, MAPT
2error-free translesion synthesisGO:007098710.7RPS27A, VCP
3negative regulation of kinase activityGO:003367310.5MAPT, MSTN
4plasma membrane repairGO:000177810.4DYSF, MYH2
5cellular protein metabolic processGO:004426710.4APOE, APP, BACE1, RPS27A
6T cell chemotaxisGO:001081810.3CXCL9, CXCR3
7muscle contractionGO:000693610.3DYSF, EMD, MYH2
8virion assemblyGO:001906810.1APOE, RPS27A

Molecular functions related to Inclusion Body Myositis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipoprotein particle bindingGO:007181311.0APOE, MAPT
2identical protein bindingGO:004280210.1APOE, APP, MAPT, MSTN, SQSTM1, TARDBP
3protein bindingGO:00055157.1APOE, APP, BACE1, COX5A, CXCL9, DYSF

Sources for Inclusion Body Myositis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet