MCID: INF043
MIFTS: 20

Infantile Apnea

Categories: Rare diseases, Respiratory diseases

Aliases & Classifications for Infantile Apnea

MalaCards integrated aliases for Infantile Apnea:

Name: Infantile Apnea 50 56
Apnea of Infancy 50 56
Infant Apnea 69
Aoi 50

Classifications:

Orphanet: 56  
Rare respiratory diseases


External Ids:

Orphanet 56 ORPHA70590

Summaries for Infantile Apnea

NIH Rare Diseases : 50 the following summary is from orphanet, a european reference portal for information on rare diseases and orphan drugs.orpha number: 70590disease definitioninfantile apnea is a cessation of respiratory air flow that may affect newborns or older children because of neurological impairment of the respiratory rhythm or obstruction of air flow through the air passages. the symptoms include cyanosis, pallor or bradycardia and snoring in case of obstructive apnea.visit the orphanet disease page for more resources. last updated: 2/29/2012

MalaCards based summary : Infantile Apnea, also known as apnea of infancy, is related to atelosteogenesis, type i and boomerang dysplasia. The drugs Cafcit Injection and Caffeine have been mentioned in the context of this disorder. Affiliated tissues include skin, heart and brain.

Wikipedia : 72 Infantile apnea is a rare disease that is characterized by cessation of breathing in an infant for at... more...

Related Diseases for Infantile Apnea

Diseases related to Infantile Apnea via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 atelosteogenesis, type i 11.6
2 boomerang dysplasia 11.0
3 atelosteogenesis, type iii 10.8
4 leigh syndrome 9.6
5 sudden infant death syndrome 9.6

Graphical network of the top 20 diseases related to Infantile Apnea:



Diseases related to Infantile Apnea

Symptoms & Phenotypes for Infantile Apnea

Drugs & Therapeutics for Infantile Apnea

FDA approved drugs:

id Drug Name Active Ingredient(s) 17 Company Approval Date
1
Cafcit Injection 17 CAFFEINE CITRATE Roxane Laboratories September 1999

Drugs for Infantile Apnea (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Caffeine Approved, Nutraceutical 58-08-2 2519
2 Anticoagulants
3 Caffeine citrate
4 Calcium, Dietary
5 Central Nervous System Stimulants
6 Chelating Agents
7 Neurotransmitter Agents
8 Phosphodiesterase Inhibitors
9 Purinergic P1 Receptor Antagonists
10 Citrate Nutraceutical
11
Citric Acid Nutraceutical, Vet_approved 77-92-9 311

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Impact of Swaddle Blanket on Gastroesophageal Reflux Unknown status NCT02083952
2 Gastroesophageal Reflux and Cardiorespiratory Problems Completed NCT03053609
3 Caffeine Citrate for the Treatment of Apnea Associated With Bronchiolitis in Young Infants Completed NCT01435486 Caffeine citrate;Normal saline
4 Late-onset Congenital Central Hypoventilation Syndrome and the Mutation of Phox2B Gene Completed NCT01225679

Search NIH Clinical Center for Infantile Apnea

Genetic Tests for Infantile Apnea

Anatomical Context for Infantile Apnea

MalaCards organs/tissues related to Infantile Apnea:

39
Skin, Heart, Brain, Eye

Publications for Infantile Apnea

Articles related to Infantile Apnea:

(show all 24)
id Title Authors Year
1
Maternally inherited Leigh syndrome: an unusual cause of infantile apnea. ( 19669818 )
2010
2
The VIIIth ESPID Conference (European Society for the Study and Prevention of Infant Death), the International Conference on Prevention of Infantile Apnea and Sudden Infant Death on the Verge of the Millenium. Jerusalem, Israel, May 30-June 3, 1999. Abstracts. ( 10372207 )
1999
3
Familial infantile apnea and immature beta oxidation. ( 8545168 )
1995
4
Nasal CPAP: use in the management of infantile apnea. ( 8177994 )
1993
5
The relationship of breathing pattern to central chemoreceptor activity in infantile apnea. ( 2126778 )
1990
6
Effects of hypomagnesemia on reactivity of bovine and ovine platelets: possible relevance to infantile apnea and sudden infant death syndrome. ( 2307807 )
1990
7
Infantile apnea monitoring and SIDS. ( 2926610 )
1989
8
A practical approach to infantile apnea. ( 3074965 )
1988
9
Infantile apnea and home monitoring. ( 3231587 )
1988
10
Infantile apnea, home monitoring, and SIDS: go back to go. ( 3333256 )
1987
11
Home monitoring for infantile apnea. ( 10284128 )
1987
12
Infantile apnea and home monitoring devices. ( 3673859 )
1987
13
Consensus development summaries. Infantile apnea and home monitoring. National Institutes of Health. ( 3829666 )
1987
14
National Institutes of Health Consensus Development Conference on Infantile Apnea and Home Monitoring, Sept 29 to Oct 1, 1986. ( 3808807 )
1987
15
Effects of maternal smoking and caffeine habits on infantile apnea: a retrospective study. ( 3725488 )
1986
16
Infantile apnea. ( 3751839 )
1986
17
Infantile apnea and home monitoring. ( 3553902 )
1986
18
American Academy of Pediatrics. Task Force on Prolonged Infantile Apnea. Prolonged infantile apnea: 1985. ( 4011346 )
1985
19
Current perspectives in infantile apnea. ( 3156118 )
1985
20
Evaluation and management of infantile apnea. ( 6709408 )
1984
21
Sudden infant dealth syndrome and infantile apnea: introduction. ( 6709407 )
1984
22
The St. Paul Infant Apnea Program. An approach to the evaluation and treatment of infantile apnea. ( 6717409 )
1984
23
Psychosocial aspects of infantile apnea and home monitoring. ( 6709409 )
1984
24
Effect of caffeine on control of breathing in infantile apnea. ( 6644439 )
1983

Variations for Infantile Apnea

Expression for Infantile Apnea

Search GEO for disease gene expression data for Infantile Apnea.

Pathways for Infantile Apnea

GO Terms for Infantile Apnea

Sources for Infantile Apnea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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