IDF
MCID: INF046
MIFTS: 30

Infantile Digital Fibromatosis (IDF) malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Infantile Digital Fibromatosis

Aliases & Descriptions for Infantile Digital Fibromatosis:

Name: Infantile Digital Fibromatosis 50 56 69
Asymptomatic Nodular Proliferation of Fibrous Tissue on the Dorsal and Lateral Aspects of the Fingers or Toes 50
Recurring Digital Fibrous Tumor of Childhood 56
Inclusion Body Fibromatosis 56
Reye Tumor 56
Idf 50

Characteristics:

Orphanet epidemiological data:

56
infantile digital fibromatosis
Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal;

Classifications:

Orphanet: 56  
Rare skin diseases


External Ids:

Orphanet 56 ORPHA199267
UMLS via Orphanet 70 C1318562
ICD10 via Orphanet 34 M72.8

Summaries for Infantile Digital Fibromatosis

MalaCards based summary : Infantile Digital Fibromatosis, also known as asymptomatic nodular proliferation of fibrous tissue on the dorsal and lateral aspects of the fingers or toes, is related to fibromatosis and 13q12.3 microdeletion syndrome, and has symptoms including skin nodule An important gene associated with Infantile Digital Fibromatosis is VIM (Vimentin), and among its related pathways/superpathways are Cytoskeleton remodeling Neurofilaments and Cytoskeletal Signaling. Affiliated tissues include skin and breast.

Wikipedia : 71 Infantile digital fibromatosis (also known as an \"Inclusion body fibromatosis,\" \"Infantile digital... more...

Related Diseases for Infantile Digital Fibromatosis

Diseases related to Infantile Digital Fibromatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
id Related Disease Score Top Affiliating Genes
1 fibromatosis 10.7
2 13q12.3 microdeletion syndrome 10.0 DES VIM
3 lymphomatous thyroiditis 10.0 DES VIM
4 osteomyelitis 10.0 DES VIM
5 myoma 10.0 DES VIM
6 congenital myasthenic syndrome 10.0 DES VIM
7 spleen angiosarcoma 10.0 DES VIM
8 marfanoid hypermobility syndrome 10.0 DES VIM
9 malignant dermis tumor 10.0 DES VIM
10 urethral cancer 10.0 DES VIM
11 adult endodermal sinus tumor 10.0 DES VIM
12 biliary papillomatosis 10.0 DES VIM
13 tanycytic ependymoma 10.0 DES VIM
14 biemond syndrome 10.0 DES VIM
15 liver angiosarcoma 10.0 DES VIM
16 phyllode tumor 10.0
17 intestinal obstruction 10.0 DES VIM
18 cavernous sinus meningioma 10.0 DES VIM
19 male reproductive system disease 10.0 DES VIM
20 petrous apex meningioma 10.0 DES VIM
21 male urethral cancer 10.0 DES VIM
22 vulvar squamous papilloma 10.0 DES VIM
23 mediastinum liposarcoma 10.0 DES VIM
24 coronary stenosis 10.0 DES VIM
25 dyslexia 10.0 DES VIM
26 sebaceous adenoma 10.0 DES VIM
27 anal gland neoplasm 10.0 DES VIM
28 glomangioma 10.0 DES VIM
29 skin glomus tumor 9.9 DES VIM
30 omodysplasia 2 9.9 DES VIM
31 congenital muscular dystrophy with hyperlaxity 9.9 DES VIM
32 t-cell childhood lymphoblastic lymphoma 9.9 DES VIM
33 pilar sheath acanthoma 9.9 DES VIM
34 lung benign neoplasm 9.9 DES VIM
35 enchondromatosis dwarfism deafness 9.9 DES VIM
36 fitz-hugh-curtis syndrome 9.9 DES VIM
37 diarrhea, chronic, with villous atrophy 9.9 DES VIM
38 jewett-marshall bladder cancer 9.9 DES VIM
39 orthostatic proteinuria 9.9 DES VIM
40 scirrhous adenocarcinoma 9.9 DES VIM
41 hyperpituitarism 9.9 DES VIM
42 caroli disease 9.9 DES VIM
43 sengers syndrome 9.9 DES VIM
44 c-p angle neurinoma 9.9 DES VIM
45 juvenile xanthogranuloma 9.9 DES VIM
46 diabetes persistent mullerian ducts 9.9 DES VIM
47 advanced sleep-phase syndrome, familial, 2 9.9 DES VIM
48 neutrophil immunodeficiency syndrome 9.9 DES VIM
49 preretinal fibrosis 9.9 DES VIM
50 palmoplantar keratosis 9.9 DES VIM

Graphical network of the top 20 diseases related to Infantile Digital Fibromatosis:



Diseases related to Infantile Digital Fibromatosis

Symptoms & Phenotypes for Infantile Digital Fibromatosis

Human phenotypes related to Infantile Digital Fibromatosis:

56 32
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 skin nodule 56 32 Obligate (100%) HP:0200036

Drugs & Therapeutics for Infantile Digital Fibromatosis

Search Clinical Trials , NIH Clinical Center for Infantile Digital Fibromatosis

Genetic Tests for Infantile Digital Fibromatosis

Anatomical Context for Infantile Digital Fibromatosis

MalaCards organs/tissues related to Infantile Digital Fibromatosis:

39
Skin, Breast

Publications for Infantile Digital Fibromatosis

Articles related to Infantile Digital Fibromatosis:

(show top 50) (show all 53)
id Title Authors Year
1
Case of infantile digital fibromatosis: Observation of its dermoscopic features. ( 27859517 )
2016
2
Benign Nerve Sheath Myxoma in an Infant Misdiagnosed as Infantile Digital Fibromatosis. ( 27196676 )
2016
3
Infantile Digital Fibromatosis: A Rare Case Report. ( 27057032 )
2016
4
A case of infantile digital fibromatosis: differential diagnosis and treatment. ( 23330824 )
2014
5
Infantile digital fibromatosis: a rare myofibrocytic tumor with characteristic histopathology. ( 25482706 )
2014
6
Anti-calponin 1 antibodies highlight intracytoplasmic inclusions of infantile digital fibromatosis. ( 24117680 )
2013
7
Infantile digital fibromatosis. ( 23241193 )
2013
8
Case report of an ulcerated infantile digital fibromatosis in an older child. The lump to spot in the child's hand (a spot not to lump in with the others). ( 23578982 )
2013
9
Diagnosis and treatment of digitocutaneous dysplasia, a rare infantile digital fibromatosis: a case report. ( 24426970 )
2013
10
Infantile digital fibromatosis (inclusion body fibromatosis) observed in a baby without finger involvement. ( 23716832 )
2013
11
Infantile digital fibromatosis: a rare tumour of infancy. Report of five cases. ( 23157779 )
2012
12
Infantile digital fibromatosis: our experience and long-term results. ( 21276743 )
2011
13
Intra-lesional steroid for the management of symptomatic Infantile Digital Fibromatosis. ( 20937573 )
2011
14
Key cytological findings in FNA from infantile digital fibromatosis. ( 21986179 )
2011
15
Congenital infantile digital fibromatosis: a case report and review of the literature. ( 21139926 )
2009
16
Benign phyllodes tumor of the breast with intracytoplasmic inclusion bodies identical to infantile digital fibromatosis. ( 18266786 )
2008
17
Infantile digital fibromatosis. ( 18571599 )
2008
18
A range of histologic findings in infantile digital fibromatosis. ( 18304159 )
2008
19
Infantile digital fibromatosis. ( 18812724 )
2008
20
Infantile digital fibromatosis. ( 17273037 )
2007
21
Further documentation of spontaneous regression of infantile digital fibromatosis. ( 17542881 )
2007
22
An unusual congenital presentation of infantile digital fibromatosis. ( 17535189 )
2007
23
Noninclusion-body infantile digital fibromatosis: a lesion heralding terminal osseous dysplasia and pigmentary defects syndrome. ( 15864382 )
2005
24
Intralesional fluorouracil injection in infantile digital fibromatosis. ( 15897374 )
2005
25
Congenital infantile digital fibromatosis. ( 12220294 )
2002
26
Infantile digital fibromatosis: an unusual localization. ( 11584416 )
2001
27
Recurrent infantile digital fibromatosis--a rare entity. ( 11883128 )
2001
28
Infantile digital fibromatosis - a case report. ( 11164672 )
2001
29
A case of infantile digital fibromatosis with spontaneous regression. ( 9769598 )
1998
30
Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. ( 7675776 )
1995
31
Recurring infantile digital fibromatosis: report of two cases. ( 7722838 )
1995
32
Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. ( 8172324 )
1994
33
Immunohistochemical identification of aggregated actin filaments in formalin-fixed, paraffin-embedded sections. I. A study of infantile digital fibromatosis by a new pretreatment. ( 1310240 )
1992
34
Infantile digital fibromatosis: ultrastructural human papillomavirus and herpes simplex virus DNA observation. ( 1656415 )
1991
35
SH abundant body in infantile digital fibromatosis--a histochemical study on distribution of sulfhydryl groups. ( 2177484 )
1990
36
Infantile digital fibromatosis. Immunohistochemical and immunoelectron microscopic studies. ( 1697612 )
1990
37
A case of infantile digital fibromatosis showing spontaneous regression. ( 2667619 )
1989
38
Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. ( 2836293 )
1988
39
Infantile digital fibromatosis. Immunohistochemical and ultrastructural observations of cytoplasmic inclusions. ( 2827878 )
1988
40
Identification of actin microfilaments in the intracytoplasmic inclusions present in recurring infantile digital fibromatosis (Reye tumor). ( 3029741 )
1986
41
Posttraumatic occurrence of infantile digital fibromatosis. A histologic and electron microscopic study. ( 3740876 )
1986
42
Infantile digital fibromatosis. An electron microscopic and immunohistochemical study. ( 3811906 )
1986
43
Infantile digital fibromatosis after web construction in syndactyly. ( 3020117 )
1986
44
Infantile digital fibromatosis. ( 6545884 )
1984
45
Infantile digital fibromatosis occurring outside the digit. ( 6496846 )
1984
46
Infantile digital fibromatosis. Identification of actin filaments in cytoplasmic inclusions by heavy meromyosin binding. ( 6311399 )
1983
47
Infantile digital fibromatosis--a case report: an electron microscope study. ( 6582225 )
1983
48
Ultrastructural histochemistry of infantile digital fibromatosis. ( 6270858 )
1981
49
Cell culture of infantile digital fibromatosis. ( 6249721 )
1980
50
Infantile digital fibromatosis. Ultrastructural, histochemical, and tissue culture observations. ( 6253042 )
1980

Variations for Infantile Digital Fibromatosis

Expression for Infantile Digital Fibromatosis

Search GEO for disease gene expression data for Infantile Digital Fibromatosis.

Pathways for Infantile Digital Fibromatosis

Pathways related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.36 DES VIM
2 11.28 CNN1 DES VIM
3 11.24 CNN1 DES
4 11.01 DES VIM
5
Show member pathways
10.61 DES VIM

GO Terms for Infantile Digital Fibromatosis

Cellular components related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.96 DES VIM
2 cytoskeleton GO:0005856 8.8 CNN1 DES VIM

Biological processes related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.96 DES VIM
2 intermediate filament organization GO:0045109 8.62 DES VIM

Molecular functions related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 DES VIM

Sources for Infantile Digital Fibromatosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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