MCID: INF046
MIFTS: 28

Infantile Digital Fibromatosis malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Infantile Digital Fibromatosis

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Sources:
30ICD10 via Orphanet, 47NIH Rare Diseases, 53Orphanet, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Infantile Digital Fibromatosis:

Name: Infantile Digital Fibromatosis 47 53 67
Asymptomatic Nodular Proliferation of Fibrous Tissue on the Dorsal and Lateral Aspects of the Fingers or Toes 47
Recurring Digital Fibrous Tumor of Childhood 53
 
Inclusion Body Fibromatosis 53
Reye Tumor 53
Idf 47

Characteristics:

Orphanet epidemiological data:

53
infantile digital fibromatosis:
Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal

Classifications:

Orphanet: 53 
Rare skin diseases


External Ids:

Orphanet53 ORPHA199267
UMLS via Orphanet68 C1318562
ICD10 via Orphanet30 M72.8

Summaries for Infantile Digital Fibromatosis

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Wikipedia:70 Infantile digital fibromatosis (also known as an \"Inclusion body fibromatosis,\" \"Infantile digital... more...

MalaCards based summary: Infantile Digital Fibromatosis, also known as asymptomatic nodular proliferation of fibrous tissue on the dorsal and lateral aspects of the fingers or toes, is related to fibromatosis and phyllode tumor, and has symptoms including Array An important gene associated with Infantile Digital Fibromatosis is VIM (Vimentin), and among its related pathways are Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers and Cytoskeletal Signaling. Affiliated tissues include skin.

Related Diseases for Infantile Digital Fibromatosis

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Diseases related to Infantile Digital Fibromatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
idRelated DiseaseScoreTop Affiliating Genes
1fibromatosis10.7
2phyllode tumor10.0
3intermittent claudication9.9
4absence of fingerprints congenital milia9.8DES, VIM
5lymphocytic vasculitis9.8DES, VIM
6terminal osseous dysplasia9.8
7fibroma9.8
8herpes simplex9.8
9skin lipoma9.8DES, VIM
10lymphangiosarcoma9.8DES, VIM
11chondroblastoma9.8DES, VIM
12pancreatic delta cell neoplasm9.8DES, VIM
13anterograde amnesia9.8DES, VIM
14pulmonary venoocclusive disease9.8DES, VIM
15monophasic synovial sarcoma9.8DES, VIM
16mollaret meningitis9.8DES, VIM
17bartholin's gland benign neoplasm9.8DES, VIM
18malignant adenofibroma9.8DES, VIM
19sclerosing liposarcoma9.8DES, VIM
20focal chorioretinitis9.8DES, VIM
21malignant glandular tumor of peripheral nerve sheath9.8DES, VIM
22skin glomangioma9.8DES, VIM
23parachordoma9.8DES, VIM
24angora hair nevus9.8DES, VIM
25short-rib thoracic dysplasia 129.8DES, VIM
26gangliocytoma9.7DES, VIM
27t-cell childhood acute lymphocytic leukemia9.7DES, VIM
28emerinopathy9.7DES, VIM
29fibrosing mediastinitis9.7DES, VIM
30staphyloenterotoxemia9.7DES, VIM
31gallbladder leiomyosarcoma9.7DES, VIM
32frontal sinus squamous cell carcinoma9.7DES, VIM
33epidural neoplasm9.7DES, VIM
34mild phosphoribosylpyrophosphate synthetase superactivity9.7DES, VIM
35anus leiomyosarcoma9.7DES, VIM
36megarbane jalkh syndrome9.6DES, VIM
37renal tubular acidosis, distal, autosomal recessive9.6DES, VIM
38advanced sleep-phase syndrome, familial, 29.6DES, VIM
39neutrophil immunodeficiency syndrome9.6DES, VIM
40mixed extragonadal germ cell cancer9.5DES, VIM
41myopathy9.5DES, VIM
42kala-azar 19.5DES, VIM
43harding ataxia9.4CNN1, DES, VIM
44amyloidosis, hereditary, transthyretin-related9.4DES, VIM
45gastrointestinal stromal tumor9.2DES, VIM

Graphical network of the top 20 diseases related to Infantile Digital Fibromatosis:



Diseases related to infantile digital fibromatosis

Symptoms for Infantile Digital Fibromatosis

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Human phenotypes related to Infantile Digital Fibromatosis:

 53
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 skin nodule53 Obligate (100%)

Drugs & Therapeutics for Infantile Digital Fibromatosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Infantile Digital Fibromatosis

Genetic Tests for Infantile Digital Fibromatosis

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Anatomical Context for Infantile Digital Fibromatosis

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MalaCards organs/tissues related to Infantile Digital Fibromatosis:

35
Skin

Animal Models for Infantile Digital Fibromatosis or affiliated genes

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Publications for Infantile Digital Fibromatosis

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Articles related to Infantile Digital Fibromatosis:

(show top 50)    (show all 53)
idTitleAuthorsYear
1
Case of infantile digital fibromatosis: Observation of its dermoscopic features. (27859517)
2016
2
Benign Nerve Sheath Myxoma in an Infant Misdiagnosed as Infantile Digital Fibromatosis. (27196676)
2016
3
A case of infantile digital fibromatosis: differential diagnosis and treatment. (23330824)
2014
4
Infantile digital fibromatosis. (23241193)
2013
5
Infantile digital fibromatosis (inclusion body fibromatosis) observed in a baby without finger involvement. (23716832)
2013
6
Case report of an ulcerated infantile digital fibromatosis in an older child. The lump to spot in the child's hand (a spot not to lump in with the others). (23578982)
2013
7
Anti-calponin 1 antibodies highlight intracytoplasmic inclusions of infantile digital fibromatosis. (24117680)
2013
8
Diagnosis and treatment of digitocutaneous dysplasia, a rare infantile digital fibromatosis: a case report. (24426970)
2013
9
Infantile digital fibromatosis: a rare tumour of infancy. Report of five cases. (23157779)
2012
10
Infantile digital fibromatosis: our experience and long-term results. (21276743)
2011
11
Intra-lesional steroid for the management of symptomatic Infantile Digital Fibromatosis. (20937573)
2011
12
Key cytological findings in FNA from infantile digital fibromatosis. (21986179)
2011
13
Congenital infantile digital fibromatosis: a case report and review of the literature. (21139926)
2009
14
Benign phyllodes tumor of the breast with intracytoplasmic inclusion bodies identical to infantile digital fibromatosis. (18266786)
2008
15
Infantile digital fibromatosis. (18812724)
2008
16
Infantile digital fibromatosis. (18571599)
2008
17
Further documentation of spontaneous regression of infantile digital fibromatosis. (17542881)
2007
18
Infantile digital fibromatosis. (17273037)
2007
19
An unusual congenital presentation of infantile digital fibromatosis. (17535189)
2007
20
Noninclusion-body infantile digital fibromatosis: a lesion heralding terminal osseous dysplasia and pigmentary defects syndrome. (15864382)
2005
21
Intralesional fluorouracil injection in infantile digital fibromatosis. (15897374)
2005
22
Congenital infantile digital fibromatosis. (12220294)
2002
23
Recurrent infantile digital fibromatosis--a rare entity. (11883128)
2001
24
Infantile digital fibromatosis - a case report. (11164672)
2001
25
Infantile digital fibromatosis: an unusual localization. (11584416)
2001
26
A case of infantile digital fibromatosis with spontaneous regression. (9769598)
1998
27
Recurring infantile digital fibromatosis: report of two cases. (7722838)
1995
28
Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. (7675776)
1995
29
Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. (8172324)
1994
30
Immunohistochemical identification of aggregated actin filaments in formalin-fixed, paraffin-embedded sections. I. A study of infantile digital fibromatosis by a new pretreatment. (1310240)
1992
31
Infantile digital fibromatosis: ultrastructural human papillomavirus and herpes simplex virus DNA observation. (1656415)
1991
32
Infantile digital fibromatosis. Immunohistochemical and immunoelectron microscopic studies. (1697612)
1990
33
SH abundant body in infantile digital fibromatosis--a histochemical study on distribution of sulfhydryl groups. (2177484)
1990
34
A case of infantile digital fibromatosis showing spontaneous regression. (2667619)
1989
35
Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. (2836293)
1988
36
Infantile digital fibromatosis. Immunohistochemical and ultrastructural observations of cytoplasmic inclusions. (2827878)
1988
37
Posttraumatic occurrence of infantile digital fibromatosis. A histologic and electron microscopic study. (3740876)
1986
38
Infantile digital fibromatosis after web construction in syndactyly. (3020117)
1986
39
Identification of actin microfilaments in the intracytoplasmic inclusions present in recurring infantile digital fibromatosis (Reye tumor). (3029741)
1986
40
Infantile digital fibromatosis. An electron microscopic and immunohistochemical study. (3811906)
1986
41
Infantile digital fibromatosis occurring outside the digit. (6496846)
1984
42
Infantile digital fibromatosis. (6545884)
1984
43
Infantile digital fibromatosis--a case report: an electron microscope study. (6582225)
1983
44
Infantile digital fibromatosis. Identification of actin filaments in cytoplasmic inclusions by heavy meromyosin binding. (6311399)
1983
45
Ultrastructural histochemistry of infantile digital fibromatosis. (6270858)
1981
46
Infantile digital fibromatosis. Ultrastructural, histochemical, and tissue culture observations. (6253042)
1980
47
Cell culture of infantile digital fibromatosis. (6249721)
1980
48
Infantile digital fibromatosis. (4431801)
1974
49
Infantile digital fibromatosis. Histopathological and electron microscopic study with a review of the literature. (4376326)
1974
50
Infantile digital fibromatosis and aponeurotic fibroma. Case reports of tow rare pseudosarcomas and review of the literature. (5761804)
1969

Variations for Infantile Digital Fibromatosis

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Expression for genes affiliated with Infantile Digital Fibromatosis

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Search GEO for disease gene expression data for Infantile Digital Fibromatosis.

Pathways for genes affiliated with Infantile Digital Fibromatosis

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Pathways related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1CNN1, DES
29.0DES, VIM
3
Show member pathways
9.0DES, VIM
4
Show member pathways
9.0DES, VIM
59.0DES, VIM

GO Terms for genes affiliated with Infantile Digital Fibromatosis

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Cellular components related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.4DES, VIM
2intermediate filamentGO:00058829.4DES, VIM
3cytoskeletonGO:00058568.5CNN1, DES, VIM

Biological processes related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament organizationGO:00451099.0DES, VIM
2muscle filament slidingGO:00300498.7DES, VIM

Molecular functions related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.0DES, VIM

Sources for Infantile Digital Fibromatosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet