MCID: INF046
MIFTS: 29

Infantile Digital Fibromatosis malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Infantile Digital Fibromatosis

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Sources:
46NIH Rare Diseases, 52Orphanet, 66UMLS, 29ICD10 via Orphanet, 67UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Infantile Digital Fibromatosis:

Name: Infantile Digital Fibromatosis 46 52 66
Asymptomatic Nodular Proliferation of Fibrous Tissue on the Dorsal and Lateral Aspects of the Fingers or Toes 46
Recurring Digital Fibrous Tumor of Childhood 52
 
Inclusion Body Fibromatosis 52
Reye Tumor 52
Idf 46

Characteristics:

Orphanet epidemiological data:

52
infantile digital fibromatosis:
Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal

Classifications:

Orphanet: 52 
Rare skin diseases


External Ids:

Orphanet52 ORPHA199267
ICD10 via Orphanet29 M72.8
UMLS via Orphanet67 C1318562

Summaries for Infantile Digital Fibromatosis

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Wikipedia:69 Infantile digital fibromatosis (also known as an \"Inclusion body fibromatosis,\" \"Infantile digital... more...

MalaCards based summary: Infantile Digital Fibromatosis, also known as asymptomatic nodular proliferation of fibrous tissue on the dorsal and lateral aspects of the fingers or toes, is related to fibromatosis and phyllode tumor. An important gene associated with Infantile Digital Fibromatosis is DES (Desmin), and among its related pathways are Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers and Cytoskeletal Signaling. Affiliated tissues include skin and breast.

Related Diseases for Infantile Digital Fibromatosis

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Diseases related to Infantile Digital Fibromatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
idRelated DiseaseScoreTop Affiliating Genes
1fibromatosis10.8
2phyllode tumor10.1
3intermittent claudication10.0
4terminal osseous dysplasia9.9
5fibroma9.9
6syndactyly9.9
7herpes simplex9.9
8absence of fingerprints congenital milia9.9DES, VIM
9lymphocytic vasculitis9.9DES, VIM
10skin lipoma9.9DES, VIM
11lymphangiosarcoma9.9DES, VIM
12chondroblastoma9.9DES, VIM
13pancreatic delta cell neoplasm9.9DES, VIM
14anterograde amnesia9.9DES, VIM
15pulmonary venoocclusive disease9.9DES, VIM
16monophasic synovial sarcoma9.9DES, VIM
17mollaret meningitis9.9DES, VIM
18bartholin's gland benign neoplasm9.9DES, VIM
19malignant adenofibroma9.9DES, VIM
20sclerosing liposarcoma9.9DES, VIM
21focal chorioretinitis9.9DES, VIM
22malignant glandular tumor of peripheral nerve sheath9.9DES, VIM
23skin glomangioma9.9DES, VIM
24parachordoma9.9DES, VIM
25angora hair nevus9.9DES, VIM
26short-rib thoracic dysplasia 129.9DES, VIM
27gangliocytoma9.8DES, VIM
28t-cell childhood acute lymphocytic leukemia9.8DES, VIM
29skene gland carcinoma9.8DES, VIM
30emerinopathy9.8DES, VIM
31fibrosing mediastinitis9.8DES, VIM
32staphyloenterotoxemia9.8DES, VIM
33gallbladder leiomyosarcoma9.8DES, VIM
34frontal sinus squamous cell carcinoma9.8DES, VIM
35epidural neoplasm9.8DES, VIM
36mild phosphoribosylpyrophosphate synthetase superactivity9.8DES, VIM
37anus leiomyosarcoma9.7DES, VIM
38megarbane jalkh syndrome9.7DES, VIM
39renal tubular acidosis, distal, autosomal recessive9.7DES, VIM
40advanced sleep-phase syndrome, familial, 29.7DES, VIM
41neutrophil immunodeficiency syndrome9.6DES, VIM
42mixed extragonadal germ cell cancer9.6DES, VIM
43myopathy9.5DES, VIM
44kala-azar 19.5DES, VIM
45amyloidosis, hereditary, transthyretin-related9.4DES, VIM
46harding ataxia9.3CNN1, DES, VIM
47gastrointestinal stromal tumor9.2DES, VIM

Graphical network of the top 20 diseases related to Infantile Digital Fibromatosis:



Diseases related to infantile digital fibromatosis

Symptoms for Infantile Digital Fibromatosis

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Drugs & Therapeutics for Infantile Digital Fibromatosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Infantile Digital Fibromatosis

Genetic Tests for Infantile Digital Fibromatosis

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Anatomical Context for Infantile Digital Fibromatosis

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MalaCards organs/tissues related to Infantile Digital Fibromatosis:

34
Skin, Breast

Animal Models for Infantile Digital Fibromatosis or affiliated genes

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Publications for Infantile Digital Fibromatosis

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Articles related to Infantile Digital Fibromatosis:

(show top 50)    (show all 52)
idTitleAuthorsYear
1
Benign Nerve Sheath Myxoma in an Infant Misdiagnosed as Infantile Digital Fibromatosis. (27196676)
2016
2
A case of infantile digital fibromatosis: differential diagnosis and treatment. (23330824)
2014
3
Infantile digital fibromatosis: a rare myofibrocytic tumor with characteristic histopathology. (25482706)
2014
4
Infantile digital fibromatosis. (23241193)
2013
5
Infantile digital fibromatosis (inclusion body fibromatosis) observed in a baby without finger involvement. (23716832)
2013
6
Case report of an ulcerated infantile digital fibromatosis in an older child. The lump to spot in the child's hand (a spot not to lump in with the others). (23578982)
2013
7
Anti-calponin 1 antibodies highlight intracytoplasmic inclusions of infantile digital fibromatosis. (24117680)
2013
8
Diagnosis and treatment of digitocutaneous dysplasia, a rare infantile digital fibromatosis: a case report. (24426970)
2013
9
Infantile digital fibromatosis: a rare tumour of infancy. Report of five cases. (23157779)
2012
10
Infantile digital fibromatosis: our experience and long-term results. (21276743)
2011
11
Intra-lesional steroid for the management of symptomatic Infantile Digital Fibromatosis. (20937573)
2011
12
Key cytological findings in FNA from infantile digital fibromatosis. (21986179)
2011
13
Congenital infantile digital fibromatosis: a case report and review of the literature. (21139926)
2009
14
Benign phyllodes tumor of the breast with intracytoplasmic inclusion bodies identical to infantile digital fibromatosis. (18266786)
2008
15
Infantile digital fibromatosis. (18812724)
2008
16
Infantile digital fibromatosis. (18571599)
2008
17
Further documentation of spontaneous regression of infantile digital fibromatosis. (17542881)
2007
18
Infantile digital fibromatosis. (17273037)
2007
19
An unusual congenital presentation of infantile digital fibromatosis. (17535189)
2007
20
Noninclusion-body infantile digital fibromatosis: a lesion heralding terminal osseous dysplasia and pigmentary defects syndrome. (15864382)
2005
21
Intralesional fluorouracil injection in infantile digital fibromatosis. (15897374)
2005
22
Congenital infantile digital fibromatosis. (12220294)
2002
23
Recurrent infantile digital fibromatosis--a rare entity. (11883128)
2001
24
Infantile digital fibromatosis - a case report. (11164672)
2001
25
Infantile digital fibromatosis: an unusual localization. (11584416)
2001
26
A case of infantile digital fibromatosis with spontaneous regression. (9769598)
1998
27
Recurring infantile digital fibromatosis: report of two cases. (7722838)
1995
28
Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. (7675776)
1995
29
Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. (8172324)
1994
30
Immunohistochemical identification of aggregated actin filaments in formalin-fixed, paraffin-embedded sections. I. A study of infantile digital fibromatosis by a new pretreatment. (1310240)
1992
31
Infantile digital fibromatosis: ultrastructural human papillomavirus and herpes simplex virus DNA observation. (1656415)
1991
32
Infantile digital fibromatosis. Immunohistochemical and immunoelectron microscopic studies. (1697612)
1990
33
SH abundant body in infantile digital fibromatosis--a histochemical study on distribution of sulfhydryl groups. (2177484)
1990
34
A case of infantile digital fibromatosis showing spontaneous regression. (2667619)
1989
35
Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. (2836293)
1988
36
Infantile digital fibromatosis. Immunohistochemical and ultrastructural observations of cytoplasmic inclusions. (2827878)
1988
37
Posttraumatic occurrence of infantile digital fibromatosis. A histologic and electron microscopic study. (3740876)
1986
38
Infantile digital fibromatosis after web construction in syndactyly. (3020117)
1986
39
Identification of actin microfilaments in the intracytoplasmic inclusions present in recurring infantile digital fibromatosis (Reye tumor). (3029741)
1986
40
Infantile digital fibromatosis. An electron microscopic and immunohistochemical study. (3811906)
1986
41
Infantile digital fibromatosis occurring outside the digit. (6496846)
1984
42
Infantile digital fibromatosis. (6545884)
1984
43
Infantile digital fibromatosis--a case report: an electron microscope study. (6582225)
1983
44
Infantile digital fibromatosis. Identification of actin filaments in cytoplasmic inclusions by heavy meromyosin binding. (6311399)
1983
45
Ultrastructural histochemistry of infantile digital fibromatosis. (6270858)
1981
46
Infantile digital fibromatosis. Ultrastructural, histochemical, and tissue culture observations. (6253042)
1980
47
Cell culture of infantile digital fibromatosis. (6249721)
1980
48
Infantile digital fibromatosis. (4431801)
1974
49
Infantile digital fibromatosis. Histopathological and electron microscopic study with a review of the literature. (4376326)
1974
50
Infantile digital fibromatosis and aponeurotic fibroma. Case reports of tow rare pseudosarcomas and review of the literature. (5761804)
1969

Variations for Infantile Digital Fibromatosis

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Expression for genes affiliated with Infantile Digital Fibromatosis

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Search GEO for disease gene expression data for Infantile Digital Fibromatosis.

Pathways for genes affiliated with Infantile Digital Fibromatosis

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Pathways related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3CNN1, DES
29.0DES, VIM
3
Show member pathways
9.0DES, VIM
4
Show member pathways
9.0DES, VIM
59.0DES, VIM

GO Terms for genes affiliated with Infantile Digital Fibromatosis

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Cellular components related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeletonGO:00451119.3DES, VIM
2intermediate filamentGO:00058829.3DES, VIM
3cytoskeletonGO:00058568.5CNN1, DES, VIM

Biological processes related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.0DES, VIM
2intermediate filament organizationGO:00451098.7DES, VIM

Molecular functions related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.0DES, VIM

Sources for Infantile Digital Fibromatosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet