MCID: INF046
MIFTS: 33

Infantile Digital Fibromatosis malady

Rare diseases, Skin diseases, Cancer diseases categories

Aliases & Classifications for Infantile Digital Fibromatosis

About this section
Sources:
42NIH Rare Diseases, 48Orphanet, 61UMLS, 62UMLS via Orphanet, 26ICD10 via Orphanet
See all sources

Aliases & Descriptions for Infantile Digital Fibromatosis:

Name: Infantile Digital Fibromatosis 42 48 61
Asymptomatic Nodular Proliferation of Fibrous Tissue on the Dorsal and Lateral Aspects of the Fingers or Toes 42
Recurring Digital Fibrous Tumor of Childhood 48
 
Inclusion Body Fibromatosis 48
Reye Tumor 48
Idf 42


Classifications:



Characteristics (Orphanet epidemiological data):

48
infantile digital fibromatosis:
Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal


External Ids:

Orphanet48 199267
UMLS via Orphanet62 C1318562
ICD10 via Orphanet26 M72.8

Summaries for Infantile Digital Fibromatosis

About this section
Wikipedia:64 Infantile digital fibromatosis (also known as an \"Inclusion body fibromatosis,\" \"Infantile digital... more...

MalaCards based summary: Infantile Digital Fibromatosis, also known as asymptomatic nodular proliferation of fibrous tissue on the dorsal and lateral aspects of the fingers or toes, is related to fibromatosis and fibroma. An important gene associated with Infantile Digital Fibromatosis is DES (desmin), and among its related pathways are Cytoskeletal Signaling and Cytoplasmic microtubules. The compounds orcein and s 100 have been mentioned in the context of this disorder. Affiliated tissues include skin and breast.

Related Diseases for Infantile Digital Fibromatosis

About this section

Diseases related to Infantile Digital Fibromatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 46)
idRelated DiseaseScoreTop Affiliating Genes
1fibromatosis31.7DES, VIM
2fibroma30.4VIM, DES
3phyllode tumor10.4
4adenomatoid tumor10.4VIM
5infantile myofibromatosis10.3DES
6terminal osseous dysplasia10.3
7herpes simplex10.3
8syndactyly10.3
9intermittent claudication10.1
10epithelioid leiomyosarcoma10.1DES, VIM
11mesenchymal chondrosarcoma10.1VIM, DES
12pseudosarcomatous fibromatosis10.1VIM, DES
13spindle cell carcinoma10.1DES, VIM
14spindle cell sarcoma10.1VIM, DES
15alveolar soft-part sarcoma10.1VIM, DES
16sertoli cell tumor10.0DES, VIM
17dermatofibrosarcoma protuberans10.0DES, VIM
18fibrous histiocytoma10.0DES, VIM
19granular cell tumor10.0VIM, DES
20endometrial stromal sarcoma10.0DES, VIM
21rhabdoid tumor10.0VIM, DES
22hemangiopericytoma10.0DES, VIM
23sex cord-gonadal stromal tumor10.0DES, VIM
24angiomyolipoma10.0VIM, DES
25malignant mixed mullerian tumor10.0VIM, DES
26glomus tumor10.0DES, VIM
27chordoma10.0VIM, DES
28smooth muscle tumor10.0DES, VIM
29giant cell tumor10.0VIM, DES
30abrikosov's tumor10.0VIM, DES
31malignant fibroxanthoma10.0VIM, DES
32pleomorphic adenoma10.0VIM, DES
33liposarcoma10.0DES, VIM
34sarcoma, synovial10.0VIM, DES
35gastrointestinal stromal tumor10.0VIM, DES
36leiomyosarcoma10.0VIM, DES
37neurilemmoma10.0DES, VIM
38mesothelioma, somatic10.0DES, VIM
39mesothelioma9.9DES, VIM
40leiomyoma9.9DES, VIM
41ewing sarcoma9.9DES, VIM
42chondrosarcoma9.9DES, VIM
43rhabdomyosarcoma9.9VIM, DES
44sarcoma9.9VIM, DES
45wilms tumor9.8VIM, DES
46fibrosarcoma9.7VIM, DES

Graphical network of the top 20 diseases related to Infantile Digital Fibromatosis:



Diseases related to infantile digital fibromatosis

Symptoms for Infantile Digital Fibromatosis

About this section

Drugs & Therapeutics for Infantile Digital Fibromatosis

About this section

Drug clinical trials:

Search ClinicalTrials for Infantile Digital Fibromatosis

Search NIH Clinical Center for Infantile Digital Fibromatosis

Genetic Tests for Infantile Digital Fibromatosis

About this section

Anatomical Context for Infantile Digital Fibromatosis

About this section

MalaCards organs/tissues related to Infantile Digital Fibromatosis:

31
Skin, Breast

Animal Models for Infantile Digital Fibromatosis or affiliated genes

About this section

Publications for Infantile Digital Fibromatosis

About this section

Articles related to Infantile Digital Fibromatosis:

(show all 49)
idTitleAuthorsYear
1
A case of infantile digital fibromatosis: differential diagnosis and treatment. (23330824)
2014
2
Infantile digital fibromatosis. (23241193)
2013
3
Anti-calponin 1 antibodies highlight intracytoplasmic inclusions of infantile digital fibromatosis. (24117680)
2013
4
Diagnosis and treatment of digitocutaneous dysplasia, a rare infantile digital fibromatosis: a case report. (24426970)
2013
5
Infantile digital fibromatosis (inclusion body fibromatosis) observed in a baby without finger involvement. (23716832)
2013
6
Case report of an ulcerated infantile digital fibromatosis in an older child. The lump to spot in the child's hand (a spot not to lump in with the others). (23578982)
2013
7
Infantile digital fibromatosis: a rare tumour of infancy. Report of five cases. (23157779)
2012
8
Intra-lesional steroid for the management of symptomatic Infantile Digital Fibromatosis. (20937573)
2011
9
Key cytological findings in FNA from infantile digital fibromatosis. (21986179)
2011
10
Infantile digital fibromatosis: our experience and long-term results. (21276743)
2011
11
Congenital infantile digital fibromatosis: a case report and review of the literature. (21139926)
2009
12
Infantile digital fibromatosis. (18812724)
2008
13
Benign phyllodes tumor of the breast with intracytoplasmic inclusion bodies identical to infantile digital fibromatosis. (18266786)
2008
14
Infantile digital fibromatosis. (18571599)
2008
15
A range of histologic findings in infantile digital fibromatosis. (18304159)
2008
16
Further documentation of spontaneous regression of infantile digital fibromatosis. (17542881)
2007
17
Infantile digital fibromatosis. (17273037)
2007
18
An unusual congenital presentation of infantile digital fibromatosis. (17535189)
2007
19
Noninclusion-body infantile digital fibromatosis: a lesion heralding terminal osseous dysplasia and pigmentary defects syndrome. (15864382)
2005
20
Intralesional fluorouracil injection in infantile digital fibromatosis. (15897374)
2005
21
Congenital infantile digital fibromatosis. (12220294)
2002
22
Recurrent infantile digital fibromatosis--a rare entity. (11883128)
2001
23
Infantile digital fibromatosis - a case report. (11164672)
2001
24
Infantile digital fibromatosis: an unusual localization. (11584416)
2001
25
A case of infantile digital fibromatosis with spontaneous regression. (9769598)
1998
26
Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. (7675776)
1995
27
Recurring infantile digital fibromatosis: report of two cases. (7722838)
1995
28
Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. (8172324)
1994
29
Immunohistochemical identification of aggregated actin filaments in formalin-fixed, paraffin-embedded sections. I. A study of infantile digital fibromatosis by a new pretreatment. (1310240)
1992
30
Infantile digital fibromatosis: ultrastructural human papillomavirus and herpes simplex virus DNA observation. (1656415)
1991
31
SH abundant body in infantile digital fibromatosis--a histochemical study on distribution of sulfhydryl groups. (2177484)
1990
32
Infantile digital fibromatosis. Immunohistochemical and immunoelectron microscopic studies. (1697612)
1990
33
A case of infantile digital fibromatosis showing spontaneous regression. (2667619)
1989
34
Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. (2836293)
1988
35
Infantile digital fibromatosis. Immunohistochemical and ultrastructural observations of cytoplasmic inclusions. (2827878)
1988
36
Posttraumatic occurrence of infantile digital fibromatosis. A histologic and electron microscopic study. (3740876)
1986
37
Infantile digital fibromatosis. An electron microscopic and immunohistochemical study. (3811906)
1986
38
Infantile digital fibromatosis after web construction in syndactyly. (3020117)
1986
39
Identification of actin microfilaments in the intracytoplasmic inclusions present in recurring infantile digital fibromatosis (Reye tumor). (3029741)
1986
40
Infantile digital fibromatosis occurring outside the digit. (6496846)
1984
41
Infantile digital fibromatosis. (6545884)
1984
42
Infantile digital fibromatosis--a case report: an electron microscope study. (6582225)
1983
43
Infantile digital fibromatosis. Identification of actin filaments in cytoplasmic inclusions by heavy meromyosin binding. (6311399)
1983
44
Ultrastructural histochemistry of infantile digital fibromatosis. (6270858)
1981
45
Infantile digital fibromatosis. Ultrastructural, histochemical, and tissue culture observations. (6253042)
1980
46
Cell culture of infantile digital fibromatosis. (6249721)
1980
47
Infantile digital fibromatosis. (4431801)
1974
48
Infantile digital fibromatosis. Histopathological and electron microscopic study with a review of the literature. (4376326)
1974
49
Infantile digital fibromatosis and aponeurotic fibroma. Case reports of tow rare pseudosarcomas and review of the literature. (5761804)
1969

Variations for Infantile Digital Fibromatosis

About this section

Expression for genes affiliated with Infantile Digital Fibromatosis

About this section
Search GEO for disease gene expression data for Infantile Digital Fibromatosis.

Pathways for genes affiliated with Infantile Digital Fibromatosis

About this section

Pathways related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1VIM, DES
2
Show member pathways
9.1VIM, DES
3
Show member pathways
Signaling by Aurora kinases36
Aurora C signaling36
9.1VIM, DES

Compounds for genes affiliated with Infantile Digital Fibromatosis

About this section

Compounds related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

(show all 43)
idCompoundScoreTop Affiliating Genes
1orcein449.6VIM, DES
2s 100449.6VIM, DES
3toluidine449.6VIM, DES
4reticulin449.6DES, VIM
5mucicarmine449.6DES, VIM
6phalloidin449.6DES, VIM
7b 723449.5DES, VIM
8gemfibrozil28 44 1111.5DES, VIM
9bezafibrate44 28 1111.5VIM, DES
10acetaldehyde28 44 2411.5DES, VIM
11dermatan sulfate449.5DES, VIM
12fenofibrate44 50 1111.5DES, VIM
13hematoxylin449.5DES, VIM
14ganglioside449.5VIM, DES
15procollagen449.5DES, VIM
16progestin449.5VIM, DES
17azathioprine44 1 50 1112.5DES, VIM
18biotin44 24 1111.5VIM, DES
19adriamycin449.5DES, VIM
20bromodeoxyuridine449.5DES, VIM
21dihydrotestosterone44 28 24 1112.5DES, VIM
22hyaluronic acid44 2410.5DES, VIM
23formaldehyde44 2410.5VIM, DES
24heparan sulfate44 2410.5VIM, DES
2512-o-tetradecanoylphorbol 13-acetate449.5VIM, DES
26methionine449.5VIM, DES
27acetylcholine44 50 28 24 1113.4DES, VIM
28doxorubicin44 50 1111.4VIM, DES
29glycogen44 2410.4VIM, DES
30actinomycin d449.4VIM, DES
31estradiol44 24 1111.4VIM, DES
32paraffin449.4DES, VIM
33proline449.4DES, VIM
34iron44 2410.4DES, VIM
35lysine449.3VIM, DES
36lactate449.3DES, VIM
37creatinine449.3DES, VIM
38heparin44 28 24 1112.2DES, VIM
39adenylate449.2VIM, DES
40cyclic amp44 2410.1DES, VIM
41testosterone44 60 24 1112.1DES, VIM
42progesterone44 28 60 24 1113.0DES, VIM
43h2o2448.8VIM, DES

GO Terms for genes affiliated with Infantile Digital Fibromatosis

About this section

Cellular components related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.1VIM, DES

Biological processes related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.1VIM, DES

Molecular functions related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:00428029.1VIM, DES
2structural constituent of cytoskeletonGO:00052008.8VIM, DES

Sources for Infantile Digital Fibromatosis

About this section
2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet