MCID: INF046
MIFTS: 33

Infantile Digital Fibromatosis malady

Rare diseases, Skin diseases, Cancer diseases categories

Aliases & Classifications for Infantile Digital Fibromatosis

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Sources:
41NIH Rare Diseases, 47Orphanet, 60UMLS, 61UMLS via Orphanet, 26ICD10 via Orphanet
See all sources

Infantile Digital Fibromatosis, Aliases & Descriptions:

Name: Infantile Digital Fibromatosis 41 47 60
Asymptomatic Nodular Proliferation of Fibrous Tissue on the Dorsal and Lateral Aspects of the Fingers or Toes 41
Recurring Digital Fibrous Tumor of Childhood 47
 
Inclusion Body Fibromatosis 47
Reye Tumor 47
Idf 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Skin diseases


Characteristics (Orphanet epidemiological data):

47
infantile digital fibromatosis:
Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal


External Ids:

Orphanet47 199267
UMLS via Orphanet61 C1318562
ICD10 via Orphanet26 M72.8

Summaries for Infantile Digital Fibromatosis

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Wikipedia:63 Infantile digital fibromatosis (also known as an \"Inclusion body fibromatosis,\" \"Infantile digital... more...

MalaCards based summary: Infantile Digital Fibromatosis, also known as asymptomatic nodular proliferation of fibrous tissue on the dorsal and lateral aspects of the fingers or toes, is related to fibromatosis and fibroma. An important gene associated with Infantile Digital Fibromatosis is DES (desmin), and among its related pathways are Cytoskeletal Signaling and Cytoplasmic microtubules. The compounds orcein and s 100 have been mentioned in the context of this disorder. Affiliated tissues include skin and breast.

Related Diseases for Infantile Digital Fibromatosis

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Diseases related to Infantile Digital Fibromatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 46)
idRelated DiseaseScoreTop Affiliating Genes
1fibromatosis31.7DES, VIM
2fibroma30.4VIM, DES
3phyllode tumor10.4
4adenomatoid tumor10.4VIM
5infantile myofibromatosis10.3DES
6terminal osseous dysplasia10.3
7herpes simplex10.3
8syndactyly10.3
9intermittent claudication10.1
10epithelioid leiomyosarcoma10.1DES, VIM
11mesenchymal chondrosarcoma10.1VIM, DES
12pseudosarcomatous fibromatosis10.1VIM, DES
13spindle cell carcinoma10.1DES, VIM
14spindle cell sarcoma10.1VIM, DES
15alveolar soft-part sarcoma10.1VIM, DES
16sertoli cell tumor10.0DES, VIM
17dermatofibrosarcoma protuberans10.0DES, VIM
18fibrous histiocytoma10.0DES, VIM
19granular cell tumor10.0VIM, DES
20endometrial stromal sarcoma10.0DES, VIM
21rhabdoid tumor10.0VIM, DES
22hemangiopericytoma10.0DES, VIM
23sex cord-gonadal stromal tumor10.0DES, VIM
24angiomyolipoma10.0VIM, DES
25malignant mixed mullerian tumor10.0VIM, DES
26glomus tumor10.0DES, VIM
27chordoma10.0VIM, DES
28smooth muscle tumor10.0DES, VIM
29giant cell tumor10.0VIM, DES
30abrikosov's tumor10.0VIM, DES
31malignant fibroxanthoma10.0VIM, DES
32pleomorphic adenoma10.0VIM, DES
33liposarcoma10.0DES, VIM
34sarcoma, synovial10.0VIM, DES
35gastrointestinal stromal tumor10.0VIM, DES
36leiomyosarcoma10.0VIM, DES
37neurilemmoma10.0DES, VIM
38mesothelioma, somatic10.0DES, VIM
39mesothelioma9.9DES, VIM
40leiomyoma9.9DES, VIM
41ewing sarcoma9.9DES, VIM
42chondrosarcoma9.9DES, VIM
43rhabdomyosarcoma9.9VIM, DES
44sarcoma9.9VIM, DES
45wilms tumor9.8VIM, DES
46fibrosarcoma9.7VIM, DES

Graphical network of the top 20 diseases related to Infantile Digital Fibromatosis:



Diseases related to infantile digital fibromatosis

Symptoms for Infantile Digital Fibromatosis

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Drugs & Therapeutics for Infantile Digital Fibromatosis

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Drug clinical trials:

Search ClinicalTrials for Infantile Digital Fibromatosis

Search NIH Clinical Center for Infantile Digital Fibromatosis

Genetic Tests for Infantile Digital Fibromatosis

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Anatomical Context for Infantile Digital Fibromatosis

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MalaCards organs/tissues related to Infantile Digital Fibromatosis:

31
Skin, Breast

Animal Models for Infantile Digital Fibromatosis or affiliated genes

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Publications for Infantile Digital Fibromatosis

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Articles related to Infantile Digital Fibromatosis:

(show all 49)
idTitleAuthorsYear
1
A case of infantile digital fibromatosis: differential diagnosis and treatment. (23330824)
2014
2
Infantile digital fibromatosis. (23241193)
2013
3
Anti-calponin 1 antibodies highlight intracytoplasmic inclusions of infantile digital fibromatosis. (24117680)
2013
4
Diagnosis and treatment of digitocutaneous dysplasia, a rare infantile digital fibromatosis: a case report. (24426970)
2013
5
Infantile digital fibromatosis (inclusion body fibromatosis) observed in a baby without finger involvement. (23716832)
2013
6
Case report of an ulcerated infantile digital fibromatosis in an older child. The lump to spot in the child's hand (a spot not to lump in with the others). (23578982)
2013
7
Infantile digital fibromatosis: a rare tumour of infancy. Report of five cases. (23157779)
2012
8
Intra-lesional steroid for the management of symptomatic Infantile Digital Fibromatosis. (20937573)
2011
9
Key cytological findings in FNA from infantile digital fibromatosis. (21986179)
2011
10
Infantile digital fibromatosis: our experience and long-term results. (21276743)
2011
11
Congenital infantile digital fibromatosis: a case report and review of the literature. (21139926)
2009
12
Infantile digital fibromatosis. (18812724)
2008
13
Benign phyllodes tumor of the breast with intracytoplasmic inclusion bodies identical to infantile digital fibromatosis. (18266786)
2008
14
Infantile digital fibromatosis. (18571599)
2008
15
A range of histologic findings in infantile digital fibromatosis. (18304159)
2008
16
Further documentation of spontaneous regression of infantile digital fibromatosis. (17542881)
2007
17
Infantile digital fibromatosis. (17273037)
2007
18
An unusual congenital presentation of infantile digital fibromatosis. (17535189)
2007
19
Noninclusion-body infantile digital fibromatosis: a lesion heralding terminal osseous dysplasia and pigmentary defects syndrome. (15864382)
2005
20
Intralesional fluorouracil injection in infantile digital fibromatosis. (15897374)
2005
21
Congenital infantile digital fibromatosis. (12220294)
2002
22
Recurrent infantile digital fibromatosis--a rare entity. (11883128)
2001
23
Infantile digital fibromatosis - a case report. (11164672)
2001
24
Infantile digital fibromatosis: an unusual localization. (11584416)
2001
25
A case of infantile digital fibromatosis with spontaneous regression. (9769598)
1998
26
Infantile digital fibromatosis: a study of the development and regression of cytoplasmic inclusion bodies. (7675776)
1995
27
Recurring infantile digital fibromatosis: report of two cases. (7722838)
1995
28
Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. (8172324)
1994
29
Immunohistochemical identification of aggregated actin filaments in formalin-fixed, paraffin-embedded sections. I. A study of infantile digital fibromatosis by a new pretreatment. (1310240)
1992
30
Infantile digital fibromatosis: ultrastructural human papillomavirus and herpes simplex virus DNA observation. (1656415)
1991
31
SH abundant body in infantile digital fibromatosis--a histochemical study on distribution of sulfhydryl groups. (2177484)
1990
32
Infantile digital fibromatosis. Immunohistochemical and immunoelectron microscopic studies. (1697612)
1990
33
A case of infantile digital fibromatosis showing spontaneous regression. (2667619)
1989
34
Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. (2836293)
1988
35
Infantile digital fibromatosis. Immunohistochemical and ultrastructural observations of cytoplasmic inclusions. (2827878)
1988
36
Posttraumatic occurrence of infantile digital fibromatosis. A histologic and electron microscopic study. (3740876)
1986
37
Infantile digital fibromatosis. An electron microscopic and immunohistochemical study. (3811906)
1986
38
Infantile digital fibromatosis after web construction in syndactyly. (3020117)
1986
39
Identification of actin microfilaments in the intracytoplasmic inclusions present in recurring infantile digital fibromatosis (Reye tumor). (3029741)
1986
40
Infantile digital fibromatosis occurring outside the digit. (6496846)
1984
41
Infantile digital fibromatosis. (6545884)
1984
42
Infantile digital fibromatosis--a case report: an electron microscope study. (6582225)
1983
43
Infantile digital fibromatosis. Identification of actin filaments in cytoplasmic inclusions by heavy meromyosin binding. (6311399)
1983
44
Ultrastructural histochemistry of infantile digital fibromatosis. (6270858)
1981
45
Infantile digital fibromatosis. Ultrastructural, histochemical, and tissue culture observations. (6253042)
1980
46
Cell culture of infantile digital fibromatosis. (6249721)
1980
47
Infantile digital fibromatosis. (4431801)
1974
48
Infantile digital fibromatosis. Histopathological and electron microscopic study with a review of the literature. (4376326)
1974
49
Infantile digital fibromatosis and aponeurotic fibroma. Case reports of tow rare pseudosarcomas and review of the literature. (5761804)
1969

Variations for Infantile Digital Fibromatosis

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Expression for genes affiliated with Infantile Digital Fibromatosis

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Search GEO for disease gene expression data for Infantile Digital Fibromatosis.

Pathways for genes affiliated with Infantile Digital Fibromatosis

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Pathways related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1VIM, DES
2
Show member pathways
9.1VIM, DES
3
Show member pathways
Signaling by Aurora kinases36
Aurora C signaling36
9.1VIM, DES

Compounds for genes affiliated with Infantile Digital Fibromatosis

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Compounds related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

(show all 43)
idCompoundScoreTop Affiliating Genes
1orcein439.6VIM, DES
2s 100439.6VIM, DES
3toluidine439.6DES, VIM
4reticulin439.6VIM, DES
5mucicarmine439.6VIM, DES
6phalloidin439.6DES, VIM
7b 723439.5VIM, DES
8gemfibrozil28 43 1211.5VIM, DES
9bezafibrate43 28 1211.5DES, VIM
10acetaldehyde28 43 2411.5VIM, DES
11dermatan sulfate439.5DES, VIM
12fenofibrate43 49 1211.5VIM, DES
13hematoxylin439.5VIM, DES
14ganglioside439.5DES, VIM
15procollagen439.5VIM, DES
16progestin439.5VIM, DES
17azathioprine43 2 49 1212.5DES, VIM
18biotin43 24 1211.5VIM, DES
19adriamycin439.5VIM, DES
20bromodeoxyuridine439.5DES, VIM
21dihydrotestosterone43 28 24 1212.5VIM, DES
22hyaluronic acid43 2410.5DES, VIM
23formaldehyde43 2410.5VIM, DES
24heparan sulfate43 2410.5VIM, DES
2512-o-tetradecanoylphorbol 13-acetate439.5DES, VIM
26methionine439.5VIM, DES
27acetylcholine43 49 28 24 1213.4VIM, DES
28doxorubicin43 49 1211.4DES, VIM
29glycogen43 2410.4VIM, DES
30actinomycin d439.4VIM, DES
31estradiol43 24 1211.4DES, VIM
32paraffin439.4VIM, DES
33proline439.4DES, VIM
34iron43 2410.4VIM, DES
35lysine439.3VIM, DES
36lactate439.3DES, VIM
37creatinine439.3VIM, DES
38heparin43 28 24 1212.2DES, VIM
39adenylate439.2VIM, DES
40cyclic amp43 2410.1VIM, DES
41testosterone43 59 24 1212.1VIM, DES
42progesterone43 28 59 24 1213.0DES, VIM
43h2o2438.8VIM, DES

GO Terms for genes affiliated with Infantile Digital Fibromatosis

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Cellular components related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.1VIM, DES

Biological processes related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.1VIM, DES

Molecular functions related to Infantile Digital Fibromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:00428029.1VIM, DES
2structural constituent of cytoskeletonGO:00052008.8VIM, DES

Products for genes affiliated with Infantile Digital Fibromatosis

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Sources for Infantile Digital Fibromatosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet