MCID: INF049
MIFTS: 22

Infantile Myofibromatosis malady

Summaries for Infantile Myofibromatosis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Infantile myofibromatosis (also known as \"Congenital generalized fibromatosis,\" and \"Congenital... more...

MalaCards: Infantile Myofibromatosis is related to hemangiopericytoma and fibrosarcoma. An important gene associated with Infantile Myofibromatosis is DES (desmin), and among its related pathways are Aurora B signaling and Cytoskeleton remodeling Neurofilaments. The compounds toluidine and phalloidin have been mentioned in the context of this disorder. Related mouse phenotype muscle.

Aliases & Classifications for Infantile Myofibromatosis

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42NIH Rare Diseases, 44Novoseek, 60UMLS
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Aliases & Descriptions:

infantile myofibromatosis 42 44 60


Related Diseases for Infantile Myofibromatosis

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17GeneCards, 18GeneDecks
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Diseases in the Myofibromatosis, Infantile, 1 family:

infantile myofibromatosis Myofibromatosis, Infantile 2

Diseases related to Infantile Myofibromatosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 77)
idRelated DiseaseScoreTop Affiliating Genes
1hemangiopericytoma30.5VIM, DES, ACTC1
2fibrosarcoma30.3ACTC1, DES, VIM
3myofibromatosis, infantile, 110.3
4intussusception10.3
5myofibromatosis, infantile 210.3
6choroiditis10.1
7myofibroma10.1
8cerebritis10.1
9rectal prolapse10.1
10hemochromatosis10.1
11congenital fibrosarcoma10.1
12hepatitis a10.1
13hepatitis10.1
14mediastinitis10.1
15pancreatitis10.1
16neonatal hemochromatosis10.1
17congenital generalized fibromatosis10.1
18adenomatoid tumor10.0VIM
19perineurioma10.0VIM
20lymphangioleiomyomatosis10.0DES
21lipoma10.0DES
22epidermolysis bullosa simplex10.0DES
23meningioma10.0VIM
24fasciitis10.0ACTC1
25myopathy10.0DES
26teratoma10.0ACTC1
27hemangioma10.0ACTC1
28endometriosis10.0ACTC1
29mesenchymal chondrosarcoma10.0DES, VIM
30liposarcoma10.0DES, VIM
31alveolar soft part sarcoma10.0DES, VIM
32adenoma10.0ACTC1
33chondrosarcoma10.0VIM, DES
34sex cord-gonadal stromal tumor10.0VIM, DES
35tuberous sclerosis10.0VIM
36papilloma10.0ACTC1
37sertoli cell tumor10.0DES, VIM
38synovial sarcoma10.0VIM, DES
39myoepithelioma10.0ACTC1, VIM
40granular cell tumor10.0VIM, DES
41angiosarcoma10.0VIM, ACTC1
42peripheral primitive neuroectodermal tumor10.0DES, VIM
43malignant peripheral nerve sheath tumor10.0ACTC1, VIM
44chordoma10.0DES, VIM
45adenoid cystic carcinoma10.0ACTC1, VIM
46cutaneous fibrous histiocytoma10.0ACTC1, DES
47adenosarcoma10.0ACTC1, DES
48embryonal rhabdomyosarcoma10.0DES, ACTC1
49medulloblastoma10.0DES, ACTC1
50desmoid tumor10.0ACTC1, DES

Graphical network of the top 20 diseases related to Infantile Myofibromatosis:



Diseases related to infantile myofibromatosis

Clinical Features for Infantile Myofibromatosis

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Drugs & Therapeutics for Infantile Myofibromatosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Infantile Myofibromatosis

Drug clinical trials:

Search ClinicalTrials for Infantile Myofibromatosis

Search NIH Clinical Center for Infantile Myofibromatosis

Search CenterWatch for Infantile Myofibromatosis

Genetic Tests for Infantile Myofibromatosis

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Anatomical Context for Infantile Myofibromatosis

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Animal Models for Infantile Myofibromatosis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Infantile Myofibromatosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.5ACTC1, DES, VIM

Publications for Infantile Myofibromatosis

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Genetic Variations for Infantile Myofibromatosis

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Expression for genes affiliated with Infantile Myofibromatosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Infantile Myofibromatosis

Search GEO for disease gene expression data for Infantile Myofibromatosis.

Pathways for genes affiliated with Infantile Myofibromatosis

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Sources:
37NCBI BioSystems Database, 12EMD Millipore, 29KEGG, 53Reactome, 4Cell Signaling Technology
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Compounds for genes affiliated with Infantile Myofibromatosis

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 24HMDB, 49PharmGKB, 2BitterDB, 59Tocris Bioscience
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Compounds related to Infantile Myofibromatosis according to GeneCards/GeneDecks:

(show all 35)
idCompoundScoreTop Affiliating Genes
1toluidine449.7DES, VIM
2phalloidin449.7DES, VIM
3gemfibrozil44 28 1111.7DES, VIM
4bezafibrate44 28 1111.6VIM, DES
5acetaldehyde44 28 2411.6DES, VIM
6fenofibrate44 49 1111.6DES, VIM
7ganglioside449.6DES, VIM
8progestin449.6VIM, DES
92-methoxyethanol449.5ACTC1, VIM
10azathioprine44 49 2 1112.5DES, VIM
11actomyosin449.5ACTC1, VIM
12adriamycin449.4VIM, DES
13bromodeoxyuridine449.4DES, VIM
14dihydrotestosterone44 28 11 2412.3DES, VIM
15heparan sulfate44 2410.3DES, VIM
16hyaluronic acid44 2410.2VIM, DES
17orcein448.9ACTC1, DES, VIM
18s 100448.9VIM, DES, ACTC1
19reticulin448.9ACTC1, DES, VIM
20mucicarmine448.9VIM, DES, ACTC1
21b 723448.9ACTC1, DES, VIM
22hematoxylin448.9VIM, DES, ACTC1
23procollagen448.9ACTC1, DES, VIM
24biotin44 11 2410.9VIM, DES, ACTC1
25formaldehyde44 249.9ACTC1, DES, VIM
26glycogen44 249.9VIM, DES, ACTC1
27paraffin448.9ACTC1, DES, VIM
28iron44 249.9VIM, DES, ACTC1
29creatinine448.8VIM, DES, ACTC1
30progesterone44 59 28 11 2412.8ACTC1, DES, VIM
31testosterone44 59 11 2411.8VIM, DES, ACTC1
32vegf448.8VIM, DES, ACTC1
33imatinib44 49 1110.7ACTC1, DES
34estrogen448.7ACTC1, DES, VIM
35retinoic acid44 249.7VIM, DES, ACTC1

GO Terms for genes affiliated with Infantile Myofibromatosis

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16Gene Ontology
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Cellular components related to Infantile Myofibromatosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.3DES, VIM
2extracellular vesicular exosomeGO:0700628.8ACTC1, VIM

Biological processes related to Infantile Myofibromatosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:0300498.5ACTC1, DES, VIM

Molecular functions related to Infantile Myofibromatosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.3DES, VIM

Products for genes affiliated with Infantile Myofibromatosis

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Sources for Infantile Myofibromatosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet