MCID: INF019
MIFTS: 26

Infectious Anterior Uveitis

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Infectious Anterior Uveitis

MalaCards integrated aliases for Infectious Anterior Uveitis:

Name: Infectious Anterior Uveitis 12 55 14
Secondary Infected Iridocyclitis 12 69
Secondary Iridocyclitis, Infectious 12
Infectious Secondary Iridocyclitis 12

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 55  
Rare eye diseases


External Ids:

Disease Ontology 12 DOID:9389
ICD10 32 H20.03
ICD9CM 34 364.03
SNOMED-CT 64 193487008 89114005
Orphanet 55 ORPHA279922
ICD10 via Orphanet 33 H20.0 H20.1 H20.2 more
UMLS 69 C0154911

Summaries for Infectious Anterior Uveitis

MalaCards based summary : Infectious Anterior Uveitis, also known as secondary infected iridocyclitis, is related to uveitis and anterior uveitis. An important gene associated with Infectious Anterior Uveitis is SOCS1 (Suppressor Of Cytokine Signaling 1), and among its related pathways/superpathways are IL-2 Pathway and Regulation of lipid metabolism Insulin signaling-generic cascades. Affiliated tissues include eye.

Related Diseases for Infectious Anterior Uveitis

Diseases in the Uveitis family:

Posterior Uveitis Intermediate Uveitis
Infectious Anterior Uveitis Anterior Uveitis
Infectious Posterior Uveitis

Diseases related to Infectious Anterior Uveitis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 uveitis 9.9
2 anterior uveitis 9.9
3 essential thrombocythemia 9.7 SOCS1 SOCS3
4 hepatitis c 9.3 SOCS3 STAT1

Symptoms & Phenotypes for Infectious Anterior Uveitis

Drugs & Therapeutics for Infectious Anterior Uveitis

Search Clinical Trials , NIH Clinical Center for Infectious Anterior Uveitis

Genetic Tests for Infectious Anterior Uveitis

Anatomical Context for Infectious Anterior Uveitis

MalaCards organs/tissues related to Infectious Anterior Uveitis:

38
Eye

Publications for Infectious Anterior Uveitis

Articles related to Infectious Anterior Uveitis:

# Title Authors Year
1
Document of treatment recommendations for non-infectious anterior uveitis. ( 28911893 )
2017
2
Current diagnostic approaches to infectious anterior uveitis. ( 21897147 )
2011

Variations for Infectious Anterior Uveitis

Expression for Infectious Anterior Uveitis

Search GEO for disease gene expression data for Infectious Anterior Uveitis.

Pathways for Infectious Anterior Uveitis

Pathways related to Infectious Anterior Uveitis according to GeneCards Suite gene sharing:

(show all 34)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.83 SOCS1 SOCS3 STAT1
2
Show member pathways
12.57 SOCS1 SOCS3 STAT1
3
Show member pathways
12.46 SOCS1 SOCS3 STAT1
4 12.27 SOCS1 SOCS3 STAT1
5
Show member pathways
12.24 SOCS1 SOCS3 STAT1
6
Show member pathways
12.2 SOCS1 SOCS3 STAT1
7
Show member pathways
12.11 SOCS1 SOCS3 STAT1
8
Show member pathways
12.08 SOCS1 SOCS3 STAT1
9
Show member pathways
11.93 SOCS1 STAT1
10
Show member pathways
11.86 SOCS1 STAT1
11
Show member pathways
11.84 SOCS1 SOCS3 STAT1
12
Show member pathways
11.8 SOCS1 SOCS3 STAT1
13 11.79 SOCS1 SOCS3
14 11.77 SOCS1 SOCS3 STAT1
15 11.76 SOCS3 STAT1
16 11.72 SOCS1 SOCS3 STAT1
17
Show member pathways
11.69 SOCS1 STAT1
18
Show member pathways
11.67 SOCS1 SOCS3
19
Show member pathways
11.62 SOCS1 SOCS3
20
Show member pathways
11.6 SOCS1 STAT1
21 11.6 SOCS1 SOCS3 STAT1
22 11.59 SOCS1 SOCS3 STAT1
23
Show member pathways
11.56 SOCS3 STAT1
24
Show member pathways
11.48 SOCS1 SOCS3 STAT1
25 11.42 SOCS1 SOCS3
26
Show member pathways
11.37 SOCS3 STAT1
27 11.24 SOCS3 STAT1
28 11.17 SOCS1 SOCS3 STAT1
29 10.94 SOCS1 SOCS3 STAT1
30
Show member pathways
10.94 SOCS1 SOCS3 STAT1
31
Show member pathways
10.92 SOCS3 STAT1
32 10.82 SOCS3 STAT1
33 10.73 SOCS1 SOCS3 STAT1
34 10.37 SOCS1 SOCS3 STAT1

GO Terms for Infectious Anterior Uveitis

Biological processes related to Infectious Anterior Uveitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.48 SOCS1 SOCS3
2 negative regulation of protein kinase activity GO:0006469 9.46 SOCS1 SOCS3
3 regulation of growth GO:0040008 9.43 SOCS1 SOCS3
4 negative regulation of signal transduction GO:0009968 9.4 SOCS1 SOCS3
5 regulation of protein phosphorylation GO:0001932 9.37 SOCS1 SOCS3
6 negative regulation of JAK-STAT cascade GO:0046426 9.32 SOCS1 SOCS3
7 negative regulation of insulin receptor signaling pathway GO:0046627 9.26 SOCS1 SOCS3
8 negative regulation of tyrosine phosphorylation of STAT protein GO:0042532 9.16 SOCS1 SOCS3
9 JAK-STAT cascade GO:0007259 9.13 SOCS1 SOCS3 STAT1
10 regulation of interferon-gamma-mediated signaling pathway GO:0060334 8.8 SOCS1 SOCS3 STAT1

Molecular functions related to Infectious Anterior Uveitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein kinase inhibitor activity GO:0004860 8.62 SOCS1 SOCS3

Sources for Infectious Anterior Uveitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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