ACS5
MCID: INF030
MIFTS: 84

Infectious Mononucleosis (ACS5) malady

Genetic diseases, Rare diseases, Infectious diseases, Eye diseases, Bone diseases, Fetal diseases, Skin diseases, Endocrine diseases, Oral diseases categories
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Summaries for Infectious Mononucleosis

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Sources:
8Disease Ontology, 21Genetics Home Reference, 43NIH Rare Diseases, 34MedlinePlus, 65Wikipedia, 47OMIM, 33MalaCards
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NIH Rare Diseases:43 Pfeiffer syndrome is a disorder that affects the bones in the skull, hands and feet. signs and symptoms can include craniosynostosis, which prevents normal skull growth and affects the shape of the head and face; distinctive facial features including bulging and wide-set eyes, a high forehead, an underdeveloped upper jaw, and a beaked nose; hearing loss; and dental problems. other features may include broad and deviated thumbs and great toes; brachydactyly; and syndactyly. it is caused by mutations in the fgfr1 or fgfr2 genes and is inherited in an autosomal dominant manner. the syndrome is divided into 3 subtypes (types 1, 2 and 3) based on the presence and severity of signs and symptoms. management typically includes various surgical interventions. last updated: 7/25/2014

MalaCards: Infectious Mononucleosis, also known as pfeiffer syndrome, is related to hepatitis and agammaglobulinemia, and has symptoms including lymphadenopathy, fever and fatigue. An important gene associated with Infectious Mononucleosis is FGFR1 (fibroblast growth factor receptor 1), and among its related pathways are Alzheimers Disease Pathway and Signaling by FGFR1 mutants. The compounds pd 161570 and fiin 1 hydrochloride have been mentioned in the context of this disorder. Affiliated tissues include pharynx, bone and spleen, and related mouse phenotypes are skeleton and endocrine/exocrine gland.

Disease Ontology:8 A viral infectious disease that results in inflammation, located in pharynx, has material basis in human herpesvirus 4 and has symptom fever, has symptom fatigue, has symptom lymphadenopathy, and has symptom splenomegaly.

Genetics Home Reference:21 Pfeiffer syndrome is a genetic disorder characterized by the premature fusion of certain skull bones (craniosynostosis). This early fusion prevents the skull from growing normally and affects the shape of the head and face. Pfeiffer syndrome also affects bones in the hands and feet.

MedlinePlus:34 Infectious mononucleosis, or "mono", is an infection usually caused by the epstein-barr virus. the virus spreads through saliva, which is why it's sometimes called "kissing disease." mono occurs most often in teens and young adults. however, you can get it at any age. symptoms of mono include fever sore throat swollen lymph glands sometimes you may also have a swollen spleen. serious problems are rare. a blood test can show if you have mono. most people get better in two to four weeks. however, you may feel tired for a few months afterward. treatment focuses on helping symptoms and includes medicines for pain and fever, warm salt water gargles and plenty of rest and fluids.

Wikipedia:65 Infectious mononucleosis (IM; also known as mono, glandular fever, Pfeiffer\'s disease, Filatov\'s... more...

Description from OMIM:47 101600

Aliases & Classifications for Infectious Mononucleosis

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Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 62UMLS, 9diseasecard, 65Wikipedia, 43NIH Rare Diseases, 22GTR, 21Genetics Home Reference, 47OMIM, 49Orphanet, 58SNOMED-CT, 35MeSH, 27ICD9CM, 40NCIt, 36MESH via Orphanet, 26ICD10 via Orphanet, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet, 25ICD10
See all sources

Classifications:



Characteristics (Orphanet epidemiological data):

49
pfeiffer syndrome:
Inheritance: Autosomal dominant; Prevalence: 1-9/100000; Age of onset: Neonatal/infancy


Aliases & Descriptions:

infectious mononucleosis 8 10 45 34 62
pfeiffer syndrome 8 9 65 43 22 21 47 45 49
craniofacial-skeletal-dermatologic dysplasia 21 47 62
acs5 43 21 49
pfeiffer type acrocephalosyndactyly 43 62
acrocephalosyndactyly, type v 65 21
noack syndrome 65 21
acrocephalopolysyndactyly type iv 62
gammaherpesviral mononucleosis 8
acrocephalosyndactylia type v 8
acrocephalosyndactyly, type 5 43
acrocephalosyndactyly type 5 49
pfeiffer's disease 8
filatov's disease 8
monocytic angina 8
glandular fever 8
mononucleosis 8
acs v 21


External Ids:

Disease Ontology8 DOID:8568, DOID:14705
ICD9CM27 075
NCIt40 C34726
OMIM47 101600
MESH via Orphanet36 C538582
ICD10 via Orphanet26 Q87.0
SNOMED-CT via Orphanet59 70410008
UMLS via Orphanet63 C2931888
ICD1025 B27, B27.0

Related Diseases for Infectious Mononucleosis

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Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Infectious Mononucleosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 273)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis30.9GUSB, TPI1, IL2RB, CD4, CD40LG
2agammaglobulinemia30.6SH2D1A, CD79A, CD40LG
3hodgkin's lymphoma30.6RAG2, IL2RB, SH2D1A
4craniosynostosis30.6FGFR2, FGFR1
5pneumonia30.6IL2RB, CD4, CD79A
6thrombocytopenia30.5CD40LG, CD79A, CD4, GUSB
7measles30.5CD4, CD79A, CD40LG
8lupus erythematosus30.4CD40LG, CD79A
9arthritis30.4CD4, RAG2, IL2RB, GUSB
10crouzon syndrome30.3FGFR2, FGFR1
11saethre-chotzen syndrome30.3FGFR2, FGFR1
12q fever30.3CD79A
13rheumatoid arthritis30.2GUSB, IL2RB, CD4, CD79A, CD40LG
14autoimmune hemolytic anemia30.2CD79A, CD40LG
15leukemia30.2GUSB, SH2D1A, IL2RB, CR2, RAG2, CD4
16achondroplasia30.2FGFR2
17syphilis30.2CD79A, CD4
18meningoencephalitis30.2CD4, CD79A
19aspergillosis30.2CD4, CD79A
20peripheral t-cell lymphoma30.2IL2RB, CD4
21thyroiditis30.2CD4, CD79A
22systemic lupus erythematosus30.1GUSB, TPI1, IL2RB, CR2, CD4, CD79A
23leukopenia30.1GUSB, CD4, CD79A
24influenza30.1IL2RB, CD4, CD79A
25diphtheria30.1IL2RB, CD4, CD79A, FGFR2
26non-hodgkin lymphoma30.1SH2D1A, IL2RB, CR2, FGFR1
27t-cell leukemia30.0CD4, RAG2, CR2, IL2RB
28eosinophilia30.0IL2RB, CD4, CD79A, FGFR1
29cryoglobulinemia29.9CD40LG, CD79A
30multiple sclerosis10.7
31tonsillitis10.5
32winkelman bethge pfeiffer syndrome10.4
33splenic infarction10.4
34chronic fatigue syndrome10.4
35pfeiffer syndrome type 110.4
36pfeiffer syndrome type 310.4
37nasopharyngitis10.4
38hemolytic anemia10.4
39myocarditis10.4
40virus associated hemophagocytic syndrome10.4
41blindness10.4
42acalculous cholecystitis10.3
43pharyngitis10.3
44neuronitis10.3
45hepatitis a10.3
46lemierre's syndrome10.3
47cervicitis10.3
48cholecystitis10.3
49liver disease10.3
50lymphadenitis10.3

Graphical network of the top 20 diseases related to Infectious Mononucleosis:



Diseases related to infectious mononucleosis

Symptoms for Infectious Mononucleosis

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Sources:
47OMIM, 8Disease Ontology
See all sources

Symptoms by clinical synopsis from OMIM:

101600

Clinical features from OMIM:

101600

Symptoms:

8 (show all 27)
  • lymphadenopathy
  • fever
  • fatigue
  • facial structural asymmetry/facial hemiatrophy/facial hemihypertrophy
  • autosomal dominant inheritance
  • turricephaly/oxycephaly/acrocephaly
  • symphalangy of fingers
  • hip dislocation/dysplasia/coxa valga/coxa vara/coxa plana
  • splenomegaly
  • lordosis
  • high vaulted/narrow palate
  • ptosis
  • syndactyly of fingers/interdigital palm
  • short neck
  • flat cheek bones/malar hypoplasia
  • prognathism/prognathia
  • broad/bifid thumb
  • short stature/dwarfism/nanism
  • carpal bones fusion/synostosis
  • high forehead
  • mouth held open
  • clinodactyly of fifth finger
  • short philtrum
  • flat face
  • broad nasal root
  • short hand/brachydactyly
  • hypertelorism

Drugs & Therapeutics for Infectious Mononucleosis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Infectious Mononucleosis

Search NIH Clinical Center for Infectious Mononucleosis

Genetic Tests for Infectious Mononucleosis

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Sources:
22GTR
See all sources

Genetic tests related to Infectious Mononucleosis:

id Genetic test Affiliating Genes
1 Pfeiffer Syndrome22

Anatomical Context for Infectious Mononucleosis

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Sources:
33MalaCards, 14FMA
See all sources

MalaCards organs/tissues related to Infectious Mononucleosis:

33
Bone, Spleen, Testes, T cells, Eye, Monocytes, B cells, Tonsil, Liver, Lymph node, Lung, Colon, Skin, Tongue, Breast, Thyroid

FMA organs/tissues related to Infectious Mononucleosis:

14
Pharynx

Animal Models for Infectious Mononucleosis or affiliated genes

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37MGI
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Publications for Infectious Mononucleosis

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52PubMed
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Articles related to Infectious Mononucleosis:

(show top 50)    (show all 567)
idTitleAuthorsYear
1
Infectious mononucleosis hepatitis; an unwelcome present for Father Christmas. (23732134)
2013
2
Idiopathic pure sudomotor failure and cholinergic urticaria in a patient after acute infectious mononucleosis infection. (22924754)
2013
3
Spontaneous splenic rupture resulted from infectious mononucleosis. (22288057)
2012
4
B-cell polyclonal activation and Epstein-Barr viral abortive lytic cycle are two key features in acute infectious mononucleosis. (21684200)
2011
5
Lymph node lesion of acute infectious mononucleosis in the elderly : a case report. (22104316)
2011
6
Alice in Wonderland syndrome and upper airway obstruction in infectious mononucleosis. (21563558)
2011
7
Effects of infectious mononucleosis and HLA-DRB1*15 in multiple sclerosis. (20051521)
2010
8
Peripheral blood alterations in a patient with infectious mononucleosis. (20507303)
2010
9
Infectious mononucleosis-like lesions, a rare manifestation of angioimmunoblastic T-cell lymphoma. (20350275)
2010
10
Case of the month. Streptococcal pharyngitis and infectious mononucleosis. (18795552)
2008
11
Symptomatic atrial fibrillation with infectious mononucleosis. (18474702)
2008
12
Methylprednisolone pulse therapy for severe immune thrombocytopenia associated with infectious mononucleosis. (17160996)
2007
13
Causes of infectious mononucleosis-like syndrome in adult patients. (16880711)
2006
14
The coexistence of hepatitis A and infectious mononucleosis. (16252202)
2005
15
Cefprozil-induced rash in infectious mononucleosis. (15827073)
2005
16
Role of screening for infectious mononucleosis in patients admitted with isolated, unilateral peritonsillar abscess. (15165311)
2004
17
Massive retropharyngeal lymphadenopathy in an infant: an unusual presentation of infectious mononucleosis. (15667689)
2004
18
Electron microscopic characteristics of peripheral blood lymphocytes in children with infectious mononucleosis. (15455094)
2004
19
A randomised controlled trial of a psycho-educational intervention to aid recovery in infectious mononucleosis. (15256300)
2004
20
Infectious mononucleosis progressing to fatal malignant lymphoma: a case report and review of the literature. (12916875)
2003
21
Amoxicillin-induced exanthema in young adults with infectious mononucleosis: demonstration of drug-specific lymphocyte reactivity. (12452866)
2002
22
Recovery from infectious mononucleosis: a case for more than symptomatic therapy? A systematic review. (12392128)
2002
23
Infectious mononucleosis in active patients: definitive answers to common questions. (20086504)
2002
24
Infectious mononucleosis, peripheral blood. Hematology morphology forum. (12243986)
2002
25
Unexpected death due to infectious mononucleosis. (12064653)
2002
26
The management of severe infectious mononucleosis tonsillitis and upper airway obstruction. (11779326)
2001
27
Spontaneous splenic rupture in infectious mononucleosis. (11554870)
2001
28
Infectious mononucleosis. A clinical review. (12420480)
2001
29
Acute complications of Epstein-Barr virus infectious mononucleosis. (10836164)
2000
30
Evaluation of two slide agglutination tests and a novel immunochromatographic assay for rapid diagnosis of infectious mononucleosis. (10973466)
2000
31
Infectious mononucleosis in middle age. (9952206)
1999
32
Infectious mononucleosis: psychological symptoms during acute and subacute phases of illness. (10068917)
1999
33
Evaluation of a novel dry latex preparation for demonstration of infectious mononucleosis heterophile antibody in comparison with three established tests. (9854070)
1999
34
Spontaneous splenic rupture in infectious mononucleosis: conservative management with gradual percutaneous drainage of a subcapsular hematoma. (10079351)
1999
35
Acyclovir for treatment of infectious mononucleosis: a meta-analysis. (10680982)
1999
36
Pseudoappendicitis preceding infectious mononucleosis. (9814402)
1998
37
Spontaneous splenic rupture and infectious mononucleosis in a forensic setting. (9825550)
1998
38
Nephrotic syndrome and concurrent infectious mononucleosis. (9090679)
1997
39
Clinical pathology case conference. Infectious mononucleosis. (9569871)
1996
40
Human and viral interleukin-10 in acute Epstein-Barr virus-induced infectious mononucleosis. (7751715)
1995
41
BLT-esterase in infectious mononucleosis. (7743659)
1995
42
Infectious mononucleosis in young children. (7605534)
1995
43
Patterns of cytokine gene expression in infectious mononucleosis. (8298133)
1994
44
Infectious mononucleosis: hemolysis by autoantibodies against triosephosphate isomerase]. (2170094)
1990
45
Infectious mononucleosis presenting as bilateral acute dacryocystitis. (2275940)
1990
46
Acute periarthritis in a patient with infectious mononucleosis. (3395388)
1988
47
Profound granulocytopenia associated with infectious mononucleosis. (4706394)
1973
48
A possible relationship between acute necrotizing ulcerative gingivitis and infectious mononucleosis. (5288705)
1971
49
Acquired Pelger-HuA5183182)
1967
50
Cerebellar disease in infectious mononucleosis. (5912007)
1966

Variations for Infectious Mononucleosis

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64UniProtKB/Swiss-Prot, 1 National Center for Biotechnology Information (Clinvar)
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UniProtKB/Swiss-Prot genetic disease variations for Infectious Mononucleosis:

64 (show all 38)
id Symbol AA change Variation ID SNP ID
1FGFR1p.Pro252ArgVAR_004111
2FGFR1p.Pro252ArgVAR_004111
3FGFR2p.Ser252TrpVAR_004115
4FGFR2p.Ser252TrpVAR_004115
5FGFR2p.Cys278PheVAR_004121
6FGFR2p.Cys278PheVAR_004121
7FGFR2p.Trp290CysVAR_004124
8FGFR2p.Trp290CysVAR_004124
9FGFR2p.Asp321AlaVAR_004129
10FGFR2p.Asp321AlaVAR_004129
11FGFR2p.Thr341ProVAR_004135
12FGFR2p.Thr341ProVAR_004135
13FGFR2p.Cys342ArgVAR_004137
14FGFR2p.Cys342ArgVAR_004137
15FGFR2p.Cys342SerVAR_004138
16FGFR2p.Cys342SerVAR_004138
17FGFR2p.Cys342TyrVAR_004139
18FGFR2p.Cys342TyrVAR_004139
19FGFR2p.Ala344ProVAR_004141
20FGFR2p.Ala344ProVAR_004141
21FGFR2p.Ser351CysVAR_004143
22FGFR2p.Ser351CysVAR_004143
23FGFR2p.Val359PheVAR_004146
24FGFR2p.Val359PheVAR_004146
25FGFR2p.Ala172PheVAR_017259
26FGFR2p.Ala172PheVAR_017259
27FGFR2p.Tyr340CysVAR_017269
28FGFR2p.Tyr340CysVAR_017269
29FGFR2p.Cys342GlyVAR_017270
30FGFR2p.Cys342GlyVAR_017270
31FGFR2p.Tyr375CysVAR_017275
32FGFR2p.Tyr375CysVAR_017275
33FGFR2p.Glu565GlyVAR_017277
34FGFR2p.Glu565GlyVAR_017277
35FGFR2p.Lys641ArgVAR_017278
36FGFR2p.Lys641ArgVAR_017278
37FGFR2p.Gly663GluVAR_017280
38FGFR2p.Gly663GluVAR_017280

Clinvar genetic disease variations for Infectious Mononucleosis:

1 (show all 13)
id Gene Name Type Significance SNP ID Assembly Location
1FGFR2NM_000141.4(FGFR2): c.1025G> A (p.Cys342Tyr)single nucleotide variantPathogenicrs121918487GRCh37Chr 10, 123276892: 123276892
2FGFR2NM_000141.4(FGFR2): c.1024T> C (p.Cys342Arg)single nucleotide variantPathogenicrs121918488GRCh37Chr 10, 123276893: 123276893
3FGFR2NM_000141.4(FGFR2): c.1021A> C (p.Thr341Pro)single nucleotide variantPathogenicrs121918495GRCh37Chr 10, 123276896: 123276896
4FGFR2NM_000141.4(FGFR2): c.870G> C (p.Trp290Cys)single nucleotide variantPathogenicrs121918499GRCh37Chr 10, 123279562: 123279562
5FGFR2NM_000141.4(FGFR2): c.817_819delGAC (p.Asp273del)deletionPathogenicrs121918503GRCh37Chr 10, 123279613: 123279615
6FGFR2NM_000141.4(FGFR2): c.799T> C (p.Ser267Pro)single nucleotide variantPathogenicrs121918505GRCh37Chr 10, 123279633: 123279633
7FGFR2FGFR2, IVSAS, G-A, -1single nucleotide variantPathogenic
8FGFR2FGFR2, 10-BP DEL/3-BP INS, NT952indelPathogenic
9FGFR2NM_000141.4(FGFR2): c.870G> T (p.Trp290Cys)single nucleotide variantPathogenicrs121918499GRCh37Chr 10, 123279562: 123279562
10FGFR2NM_000141.4(FGFR2): c.1694A> C (p.Glu565Ala)single nucleotide variantPathogenicrs121918506GRCh37Chr 10, 123256215: 123256215
11FGFR2FGFR2, IVSDS, A-G, +3single nucleotide variantPathogenic
12FGFR2NM_000141.4(FGFR2): c.962A> C (p.Asp321Ala)single nucleotide variantPathogenicrs121918510GRCh37Chr 10, 123276955: 123276955
13FGFR1NM_023110.2(FGFR1): c.755C> G (p.Pro252Arg)single nucleotide variantPathogenicrs121909627GRCh37Chr 8, 38282208: 38282208

Expression for genes affiliated with Infectious Mononucleosis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Infectious Mononucleosis

Search GEO for disease gene expression data for Infectious Mononucleosis.

Pathways for genes affiliated with Infectious Mononucleosis

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Sources:
50PathCards, 53QIAGEN, 55Reactome, 38NCBI BioSystems Database, 5Cell Signaling Technology, 30KEGG
See all sources

Pathways related to Infectious Mononucleosis according to GeneCards/GeneDecks:

(show all 16)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9FGFR1, FGFR2
2
Show member pathways
9.9FGFR1, FGFR2
39.9FGFR1, FGFR2
49.7IL2RB, CD40LG
5
Show member pathways
9.4FGFR1, FGFR2, CD79A
69.2FGFR1, FGFR2, IL2RB, SH2D1A
7
Show member pathways
8.7IL2RB, CD4, FGFR2, FGFR1
8
Show member pathways
8.7IL2RB, CD4, FGFR2, FGFR1
9
Show member pathways
8.7IL2RB, CD4, FGFR2, FGFR1
10
Show member pathways
8.5CD4, CD79A, FGFR2, FGFR1
11
Show member pathways
8.5IL2RB, CR2, CD79A, FGFR2, FGFR1
128.4SH2D1A, IL2RB, CD4, CD79A
13
Show member pathways
BCR signaling pathway38
TCR Signaling Pathway38
8.3CD40LG, CD79A, CD4, CR2
14
Show member pathways
8.3IL2RB, CD4, CD40LG, FGFR2, FGFR1
158.2CD40LG, CD79A, CD4, RAG2
16
Show member pathways
8.2CD4, CD79A, CD40LG, FGFR2, FGFR1

Compounds for genes affiliated with Infectious Mononucleosis

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Sources:
61Tocris Bioscience, 45Novoseek, 11DrugBank, 51PharmGKB, 24HMDB, 29IUPHAR, 3BitterDB
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Compounds related to Infectious Mononucleosis according to GeneCards/GeneDecks:

(show top 50)    (show all 98)
idCompoundScoreTop Affiliating Genes
1pd 1615706110.2FGFR2, FGFR1
2fiin 1 hydrochloride6110.2FGFR2, FGFR1
3su 54026110.2FGFR2, FGFR1
4su54024510.2FGFR1, FGFR2
5pd 17307445 6111.1FGFR1, FGFR2
6palifermin45 1111.1FGFR2, FGFR1
7sulfolipid i4510.0CD40LG, CD79A
8sandoglobulin4510.0CD79A, CD40LG
9streptavidin459.7FGFR2, CR2, IL2RB
10gamma globulin459.6CD40LG, CD79A
11mycophenolate mofetil45 51 1111.5CD40LG, CD79A, IL2RB
12ivig459.5IL2RB, CD79A, CD40LG
13cytidine45 24 1111.4RAG2, CD79A, CD40LG
14agar459.4FGFR1, FGFR2, CD40LG, CD79A
15suramin45 29 1111.4CD79A, FGFR2, FGFR1
16dextran sulfate459.4CD4, CD40LG, FGFR1
17azathioprine45 3 51 1112.3IL2RB, CD79A, FGFR2
18vitamin b12459.3CD40LG, CD79A, GUSB
19ganglioside459.2CD4, CD40LG, FGFR2
20n acetylcysteine459.2FGFR2, CD40LG, CD79A, IL2RB
21erythromycin45 3 51 1112.2GUSB, IL2RB, CD40LG, FGFR2
22hemocyanin459.2CD40LG, CD79A, CD4
23mannan459.2CD40LG, CD79A, CD4
24okt3459.2IL2RB, CR2, CD79A, CD40LG
25paraffin459.0FGFR2, CD40LG, CD79A, CR2
26lactulose459.0CD79A, GUSB
2712-o-tetradecanoylphorbol 13-acetate459.0FGFR1, FGFR2, CD4, IL2RB
28aspirin45 51 29 2411.9GUSB, IL2RB, CD79A, CD40LG
29vegf458.9IL2RB, CD79A, CD40LG, FGFR2, FGFR1
30cyclosporin a45 29 6110.9IL2RB, CR2, CD79A, CD40LG
31proline458.8TPI1, IL2RB, CD4, FGFR2
32neopterin458.8CD40LG, CD79A, CD4, IL2RB
33phosphotyrosine458.8SH2D1A, IL2RB, CD4, FGFR2, FGFR1
34estrogen458.7CR2, CD79A, CD40LG, FGFR2, FGFR1
35retinoic acid45 249.7IL2RB, CD79A, CD40LG, FGFR2, FGFR1
36histamine45 29 2410.7GUSB, IL2RB, CD79A, CD40LG, FGFR1
37creatinine458.6GUSB, TPI1, IL2RB, CD79A, CD40LG
38dopamine45 29 24 1111.6GUSB, CD79A, CD40LG, FGFR1
39phosphatidylinositol458.5IL2RB, CR2, CD4, FGFR2, FGFR1
40lactate458.4GUSB, TPI1, IL2RB, CD79A, CD40LG, FGFR1
41threonine458.3SH2D1A, IL2RB, CR2, CD4, FGFR2, FGFR1
42cysteine458.2TPI1, CD4, CD79A, CD40LG, FGFR2, FGFR1
43polysaccharide458.2FGFR1, FGFR2, CD40LG, CD79A, CD4, IL2RB
44pge2458.1GUSB, IL2RB, CD4, CD79A, CD40LG
45genistein45 29 61 3 24 1113.1GUSB, IL2RB, CD4, CD40LG, FGFR2, FGFR1
46heparin45 29 24 1111.0GUSB, CD4, CD79A, CD40LG, FGFR2, FGFR1
47tyrosine457.9SH2D1A, TPI1, IL2RB, CR2, CD4, FGFR2
48glutamate457.7GUSB, TPI1, CD4, CD79A, CD40LG, FGFR2
49calcium45 51 24 1110.6GUSB, SH2D1A, IL2RB, CR2, CD4, FGFR2
50serine457.4TPI1, IL2RB, CR2, RAG2, CD4, CD40LG

GO Terms for genes affiliated with Infectious Mononucleosis

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Sources:
16Gene Ontology
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Cellular components related to Infectious Mononucleosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098977.6CD40LG, CD79A, CD4, CR2, IL2RB
2plasma membraneGO:0058867.3CR2, CD4, CD79A, CD40LG, FGFR2, FGFR1

Biological processes related to Infectious Mononucleosis according to GeneCards/GeneDecks:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentGO:03560710.2FGFR1, FGFR2
2ventricular zone neuroblast divisionGO:02184710.1FGFR2, FGFR1
3positive regulation of phospholipase activityGO:01051810.1FGFR1, FGFR2
4mesenchymal cell differentiationGO:04876210.1FGFR1, FGFR2
5lung-associated mesenchyme developmentGO:06048410.1FGFR1, FGFR2
6branching involved in salivary gland morphogenesisGO:06044510.1FGFR2, FGFR1
7positive regulation of cardiac muscle cell proliferationGO:06004510.0FGFR1, FGFR2
8skeletal system morphogenesisGO:04870510.0FGFR2, FGFR1
9positive regulation of cell cycleGO:0457879.9FGFR1, FGFR2
10ureteric bud developmentGO:0016579.9FGFR1, FGFR2
11midbrain developmentGO:0309019.8FGFR1, FGFR2
12positive regulation of mesenchymal cell proliferationGO:0020539.6FGFR1, FGFR2
13B cell proliferationGO:0421009.4CR2, CD79A, CD40LG
14B cell differentiationGO:0301838.9CD40LG, CD79A, RAG2, CR2
15innate immune responseGO:0450878.7FGFR1, FGFR2, CD4, CR2

Molecular functions related to Infectious Mononucleosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1fibroblast growth factor-activated receptor activityGO:0050079.9FGFR1, FGFR2
2fibroblast growth factor bindingGO:0171349.9FGFR2, FGFR1
3transmembrane signaling receptor activityGO:0048888.6CD79A, CD4, CR2
4protein homodimerization activityGO:0428038.3CD4, FGFR2, FGFR1, CR2

Products for genes affiliated with Infectious Mononucleosis

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Sources for Infectious Mononucleosis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet