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MCID: INF030
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Infectious Mononucleosis malady |
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Sources: 6Disease Ontology, 17Genetics Home Reference, 30NIH Rare Diseases, 23MedlinePlus, 44Wikipedia, 33OMIM, 22MalaCards See all sources Export this MalaCard |
NIH Rare Diseases: Pfeiffer syndrome is a disorder that affects the bones in the skull, hands and feet. Signs and symptoms can include craniosynostosis, which prevents normal skull growth and affects the shape of the head and face; distinctive facial features including bulging and wide-set eyes, a high forehead, an underdeveloped upper jaw, and a beaked nose; hearing loss; and dental problems. Other features may include broad and deviated thumbs and great toes; brachydactyly; and syndactyly. It is caused by mutations in the FGFR1 or FGFR2 genes and is inherited in an autosomal dominant manner. The syndrome is divided into 3 subtypes (types 1, 2 and 3) based on the presence and severity of signs and symptoms. Management typically includes various surgical interventions.30
MalaCards: Infectious Mononucleosis, also known as pfeiffer syndrome, is related to lymphoproliferative disease, x-linked and proteinuria, and has symptoms including fever, fatigue and lymphadenopathy. An important gene associated with Infectious Mononucleosis is TPI1 (triosephosphate isomerase 1), and among its related pathways are Primary immunodeficiency and IL-15 Signaling and its Primary Biological Effects in Different Immune Cell Types. The compounds ionomycin and ivig have been mentioned in the context of this disorder. Affiliated tissues include pharynx, spleen and colon, and related mouse phenotypes are renal/urinary system and endocrine/exocrine gland. Disease Ontology: A viral infectious disease that results in inflammation, located in pharynx, has material basis in human herpesvirus 4 and has symptom fever, has symptom fatigue, has symptom lymphadenopathy, and has symptom splenomegaly.6 Genetics Home Reference: Pfeiffer syndrome is a genetic disorder characterized by the premature fusion of certain skull bones (craniosynostosis). This early fusion prevents the skull from growing normally and affects the shape of the head and face. Pfeiffer syndrome also affects bones in the hands and feet.17 MedlinePlus: Infectious mononucleosis, or "mono", is an infection caused by the epstein-barr virus. the virus spreads through saliva, which is why it's sometimes called "kissing disease." mono occurs most often in 15 to 17-year-olds. however, you can get it at any age. symptoms of mono include fever sore throat swollen lymph glands sometimes you may also have a swollen spleen. serious problems are rare. a blood test can show if you have mono. most people get better in two to four weeks. however, you may feel tired for a few months afterward. treatment focuses on helping symptoms and includes medicines for pain and fever, warm salt water gargles and plenty of rest and fluids.23 Wikipedia: Infectious mononucleosis (IM; also known as EBV infectious mononucleosis, Pfeiffer\'s disease,...44 more... OMIM: 101600 |
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Sources: 6Disease Ontology, 7diseasecard, 44Wikipedia, 30NIH Rare Diseases, 17Genetics Home Reference, 8DISEASES, 33OMIM, 32Novoseek , 23MedlinePlus, 2CDC, 43UMLS, 40SNOMED-CT, 24MeSH, 27NCIt, 19ICD9CM See all sources |
Aliases & Descriptions:
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Sources: 33OMIM, 6Disease Ontology See all sources |
Clinical features from OMIM: 101600
Symptoms: fever, fatigue, lymphadenopathy, splenomegaly.6 |
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for infectious mononucleosis Drug clinical trials:Search ClinicalTrials for infectious mononucleosis Search NIH Clinical Center for infectious mononucleosis Search CenterWatch for infectious mononucleosis |
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Sources: 11FMA, 22MalaCards See all sources |
MalaCards organs/tissues related to infectious mononucleosis:22Spleen, Colon, Monocytes, T cells, B cells FMA organs/tissues related to infectious mononucleosis:11Pharynx
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to infectious mononucleosis:25 (show all 15)
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Sources: 35PubMed See all sources |
Articles related to infectious mononucleosis:(show all 35)
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Sources: 1BioGPS See all sources |
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Sources: 20KEGG, 37R&D Systems, 38Reactome, 41Thomson Reuters, 3Cell Signaling Technology, 10EMD Millipore, 36QIAGEN See all sources |
Pathways related to infectious mononucleosis according to GeneDecks:(show top 50) (show all 67)
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Sources: 32Novoseek , 42Tocris Bioscience, 34PharmGKB, 9DrugBank, 18HMDB See all sources |
Compounds related to infectious mononucleosis according to GeneDecks:(show top 50) (show all 196)
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Sources: 12Gene Ontology See all sources |
Cellular components related to infectious mononucleosis according to GeneDecks:
Biological processes related to infectious mononucleosis according to GeneDecks:(show all 29)
Molecular functions related to infectious mononucleosis according to GeneDecks:
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