MCID: INF133
MIFTS: 29

Inferior Vena Cava Interruption malady

Categories: Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Inferior Vena Cava Interruption

Aliases & Descriptions for Inferior Vena Cava Interruption:

Name: Inferior Vena Cava Interruption 56
Inferior Caval Vein Interruption 56
Ivc Interruption 56

Classifications:



External Ids:

Orphanet 56 ORPHA99123
ICD10 via Orphanet 34 Q26.8

Summaries for Inferior Vena Cava Interruption

MalaCards based summary : Inferior Vena Cava Interruption, also known as inferior caval vein interruption, is related to pulmonary embolism and stt3a-cdg and stt3b-cdg. An important gene associated with Inferior Vena Cava Interruption is F5 (Coagulation Factor V), and among its related pathways/superpathways are Folate Metabolism and Formation of Fibrin Clot (Clotting Cascade). The drugs Kava and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and heart, and related phenotype is integument.

Related Diseases for Inferior Vena Cava Interruption

Diseases related to Inferior Vena Cava Interruption via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
id Related Disease Score Top Affiliating Genes
1 pulmonary embolism 10.2
2 stt3a-cdg and stt3b-cdg 10.1 F5 SERPINE1
3 lymphocytic colitis 10.1 F5 SERPINE1
4 neuroaxonal dystrophy 10.1 F5 SERPINE1
5 inherited blood coagulation disease 10.1 F5 SERPINE1
6 microphthalmia, isolated, with coloboma 10 10.1 F5 SERPINE1
7 czech dysplasia 10.1 F5 SERPINE1
8 mental retardation hypotonia skin hyperpigmentation 10.0 F5 SERPINE1
9 neutropenia 10.0 MTHFR SERPINE1
10 glutathionuria 10.0 MTHFR SERPINE1
11 brill-zinsser disease 10.0 F5 SERPINE1
12 multiple familial trichoepithelioma 10.0 F5 MTHFR
13 arcus senilis 10.0 MTHFR SERPINE1
14 vascular erectile tumor 10.0 F5 MTHFR
15 supraumbilical midabdominal raphe and facial cavernous hemangiomas 10.0 F5 MTHFR
16 lung cancer 10.0 F5 MTHFR
17 hypertrichosis 10.0 F5 MTHFR
18 left-right axis malformations 10.0 F5 MTHFR
19 myosclerosis, congenital 10.0 F5 MTHFR
20 photosensitive epilepsy 9.9 F5 MTHFR
21 cryptosporidiosis 9.9 F5 MTHFR
22 angular blepharoconjunctivitis 9.9 F5 MTHFR
23 houlston ironton temple syndrome 9.9 F5 MTHFR
24 blepharoconjunctivitis 9.9 F5 MTHFR
25 gastrointestinal defects and immunodeficiency syndrome 9.9 F5 MTHFR
26 villous adenoma 9.9 F5 MTHFR
27 pancreas adenocarcinoma 9.9 MTHFR SERPINE1
28 ophthalmia neonatorum 9.9 F5 MTHFR
29 vaginal discharge 9.9 F5 MTHFR
30 alcoholic gastritis 9.9 F5 MTHFR
31 thrombophilia due to activated protein c resistance 9.9 F5 MTHFR
32 thrombosis 9.9
33 heart disease 9.9
34 dextrocardia 9.9
35 spinal multifocal clear cell meningioma 9.9 F5 MTHFR
36 cleft lip 9.9 F5 MTHFR
37 sertoli-leydig cell tumor 9.8 F5 MTHFR
38 macular degeneration, age-related, 12 9.8 MTHFR SERPINE1
39 childhood type dermatomyositis 9.8 F5 MTHFR
40 dentine erosion 9.8 F5 MTHFR
41 absence of innominate vein 9.8 F5 MTHFR SERPINE1
42 aminoaciduria 9.8 F5 MTHFR SERPINE1
43 lubinsky syndrome 9.8 F5 MTHFR SERPINE1
44 bullous skin disease 9.8 F5 MTHFR SERPINE1
45 central congenital hypothyroidism 9.8 F5 MTHFR SERPINE1
46 lynch syndrome 9.8 F5 MTHFR SERPINE1
47 dysgammaglobulinemia 9.8 F5 MTHFR SERPINE1
48 scar contracture 9.8 F5 MTHFR SERPINE1
49 uterine corpus cancer 9.8 F5 MTHFR SERPINE1
50 pregnancy loss, recurrent 1 9.8 F5 MTHFR SERPINE1

Graphical network of the top 20 diseases related to Inferior Vena Cava Interruption:



Diseases related to Inferior Vena Cava Interruption

Symptoms & Phenotypes for Inferior Vena Cava Interruption

MGI Mouse Phenotypes related to Inferior Vena Cava Interruption:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.8 F5 MTHFR SERPINE1

Drugs & Therapeutics for Inferior Vena Cava Interruption

Drugs for Inferior Vena Cava Interruption (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Kava Nutraceutical Phase 4 9000-38-8
2
Epinephrine Approved, Vet_approved 51-43-4 5816
3 Mydriatics
4 Adrenergic Agents
5 Adrenergic Agonists
6 Adrenergic alpha-Agonists
7 Adrenergic beta-Agonists
8 Neurotransmitter Agents
9 Peripheral Nervous System Agents
10 Vasoconstrictor Agents
11 Epinephryl borate
12 Anti-Asthmatic Agents
13 Racepinephrine
14 Liver Extracts
15 Respiratory System Agents
16 Autonomic Agents
17 Bronchodilator Agents

Interventional clinical trials:


id Name Status NCT ID Phase
1 PREPIC 2 : Prevention of Recurrent Pulmonary Embolism by Vena Cava Interruption Completed NCT00457158 Phase 4
2 Defining Immunodeficiency in Heterotaxy Syndrome: Pilot Study Data Completed NCT01929967
3 A Prospective, Multi-Center Study of the Bard® Denali™ Retrievable Inferior Vena Cava Filter System Completed NCT01305564
4 RexMedical- Option* Vena Cava Filter IDE Study Completed NCT00488865
5 Prospective, Multi-center, Single-arm Study to Assess the Safety of Retrieval of the Recovery G2 Filter. Completed NCT00556426
6 Adrenal Function After Living Kidney Donation Completed NCT00251836
7 Total Hemihepatic Vascular Exclusion in Hepatectomy in Hepatocellular Carcinoma Treatment Completed NCT00827047

Search NIH Clinical Center for Inferior Vena Cava Interruption

Genetic Tests for Inferior Vena Cava Interruption

Anatomical Context for Inferior Vena Cava Interruption

MalaCards organs/tissues related to Inferior Vena Cava Interruption:

39
Lung, Liver, Heart

Publications for Inferior Vena Cava Interruption

Articles related to Inferior Vena Cava Interruption:

(show all 21)
id Title Authors Year
1
Catheter ablation of atrial arrhythmias in a patient with surgically corrected congenital heart disease and inferior vena cava interruption. ( 26136634 )
2015
2
Transapical closure of paraprosthetic mitral leak in a patient with inferior vena cava interruption and azygos continuation. ( 24048023 )
2013
3
Inferior vena cava interruption in a liver transplantation deceased donor. ( 23230844 )
2013
4
Deep vein thrombosis, inferior vena cava interruption and multiple thrombophilic gene mutations. ( 21642818 )
2011
5
Atrial flutter ablation through the azygous continuation in a patient with inferior vena cava interruption. ( 21030393 )
2011
6
Infrahepatic caudal/inferior vena cava interruption with azygos/hemiazygos continuation. Vascular anomaly in swine. ( 22933907 )
2010
7
Pulmonary embolism associated with inferior vena cava interruption: multidetector computed tomography findings. ( 20498625 )
2010
8
Radiofrequency ablation of atrioventricular nodal tachycardia in a patient with dextrocardia, inferior vena cava interruption, and azygos continuation. ( 18031517 )
2008
9
Catheter ablation of left free wall accessory pathway in a patient with inferior vena cava interruption. ( 12674185 )
2002
10
Inferior vena cava interruption: how and when? ( 10774449 )
2000
11
The Vena Tech filter: evaluation of a new inferior vena cava interruption device. ( 1939334 )
1991
12
Inferior vena cava interruption with renal vein collar continuation: CT and MRI appearance. ( 1773417 )
1991
13
Transvenous devices for inferior vena cava interruption. ( 2585660 )
1989
14
Inferior vena cava interruption with the Hunter-Sessions balloon: eighteen years' experience in 191 cases. ( 2795770 )
1989
15
Recurrent, fatal pulmonary embolism despite inferior vena cava interruption with the Greenfield filter. ( 3577368 )
1987
16
Inferior vena cava interruption. ( 3874355 )
1985
17
Inferior vena cava interruption in the management of pulmonary embolism. ( 7140404 )
1982
18
Requirements for a method of transvenous inferior vena cava interruption. ( 7436725 )
1980
19
Diagnosis of pulmonary embolism: correlation of value of perfusion lung scan and pulmonary arteriography in selecting patients for inferior vena cava interruption. ( 637417 )
1978
20
Inferior vena cava interruption: a new indication? ( 1164184 )
1975
21
Fatal complications following inferior vena cava interruption. ( 5159420 )
1971

Variations for Inferior Vena Cava Interruption

Expression for Inferior Vena Cava Interruption

Search GEO for disease gene expression data for Inferior Vena Cava Interruption.

Pathways for Inferior Vena Cava Interruption

GO Terms for Inferior Vena Cava Interruption

Cellular components related to Inferior Vena Cava Interruption according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 8.62 F5 SERPINE1

Biological processes related to Inferior Vena Cava Interruption according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 8.96 F5 SERPINE1
2 blood circulation GO:0008015 8.62 F5 MTHFR

Sources for Inferior Vena Cava Interruption

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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