MCID: INF133
MIFTS: 35

Inferior Vena Cava Interruption malady

Cardiovascular diseases, Fetal diseases, Rare diseases categories
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Summaries for Inferior Vena Cava Interruption

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MalaCards based summary: Inferior Vena Cava Interruption, also known as inferior caval vein interruption, is related to pulmonary embolism and dextrocardia. An important gene associated with Inferior Vena Cava Interruption is F5 (coagulation factor V (proaccelerin, labile factor)), and among its related pathways are Response to elevated platelet cytosolic Ca2+ and Complement and coagulation cascades. The compounds batroxobin and ancrod have been mentioned in the context of this disorder. Affiliated tissues include liver and lung, and related mouse phenotype integument.

Aliases & Classifications for Inferior Vena Cava Interruption

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Sources:
48Orphanet, 26ICD10 via Orphanet
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Inferior Vena Cava Interruption, Aliases & Descriptions:

Name: Inferior Vena Cava Interruption 48
Inferior Caval Vein Interruption 48
 
Ivc Interruption 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases, Rare diseases
Anatomical: Cardiovascular diseases


External Ids:

ICD10 via Orphanet26 Q26.8

Related Diseases for Inferior Vena Cava Interruption

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Diseases related to Inferior Vena Cava Interruption via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 44)
idRelated DiseaseScoreTop Affiliating Genes
1pulmonary embolism31.0F5, MTHFR
2dextrocardia10.4
3double inferior vena cava10.4
4coronary thrombosis10.4SERPINE1
5branch retinal artery occlusion10.4F5
6meningococcemia10.3F5
7eclampsia10.3MTHFR
8severe pre-eclampsia10.1F5, SERPINE1
9disseminated intravascular coagulation10.1F5, SERPINE1
10septic shock10.1F5, SERPINE1
11central retinal vein occlusion10.0F5, MTHFR
12factor v leiden thrombophilia10.0F5, SERPINE1
13hepatic vein thrombosis10.0MTHFR, F5
14retinal vein occlusion10.0F5, MTHFR
15blood protein disease10.0F5, MTHFR
16portal vein thrombosis10.0MTHFR, F5
17antithrombin iii deficiency10.0MTHFR, F5
18intracranial thrombosis10.0MTHFR, F5
19homocysteinemia10.0F5, MTHFR
20arteriosclerosis10.0MTHFR, SERPINE1
21placental abruption10.0F5, MTHFR
22congenital heart disease10.0MTHFR, SERPINE1
23sepsis10.0F5, SERPINE1
24homocystinuria10.0MTHFR, F5
25pregnancy loss10.0F5, MTHFR
26diabetic nephropathy10.0SERPINE1, MTHFR
27antiphospholipid syndrome10.0F5, MTHFR
28coronary artery anomaly9.9SERPINE1, MTHFR
29diabetes mellitus9.9MTHFR, SERPINE1
30type 2 diabetes mellitus9.8SERPINE1, MTHFR
31protein s deficiency9.8F5, MTHFR, SERPINE1
32hellp syndrome9.8SERPINE1, MTHFR, F5
33protein c deficiency9.8SERPINE1, MTHFR, F5
34thrombophilia9.8F5, MTHFR, SERPINE1
35thromboembolism9.8SERPINE1, MTHFR, F5
36venous thrombosis9.8F5, MTHFR, SERPINE1
37hyperhomocysteinemia9.8F5, MTHFR, SERPINE1
38stroke, ischemic9.8F5, MTHFR, SERPINE1
39hypertension9.8SERPINE1, MTHFR, F5
40vascular disease9.8F5, MTHFR, SERPINE1
41pre-eclampsia9.8SERPINE1, MTHFR, F5
42cerebrovascular disease9.8SERPINE1, MTHFR, F5
43myocardial infarction9.8SERPINE1, MTHFR, F5
44primary hyperoxaluria9.8MTHFR, SERPINE1

Graphical network of the top 20 diseases related to Inferior Vena Cava Interruption:



Diseases related to inferior vena cava interruption

Symptoms for Inferior Vena Cava Interruption

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Drugs & Therapeutics for Inferior Vena Cava Interruption

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Drug clinical trials:

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Search NIH Clinical Center for Inferior Vena Cava Interruption

Genetic Tests for Inferior Vena Cava Interruption

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Anatomical Context for Inferior Vena Cava Interruption

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MalaCards organs/tissues related to Inferior Vena Cava Interruption:

32
Liver, Lung

Animal Models for Inferior Vena Cava Interruption or affiliated genes

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MGI Mouse Phenotypes related to Inferior Vena Cava Interruption:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.5F5, MTHFR, SERPINE1

Publications for Inferior Vena Cava Interruption

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Articles related to Inferior Vena Cava Interruption:

(show all 20)
idTitleAuthorsYear
1
Transapical closure of paraprosthetic mitral leak in a patient with inferior vena cava interruption and azygos continuation. (24048023)
2013
2
Inferior vena cava interruption in a liver transplantation deceased donor. (23230844)
2013
3
Atrial flutter ablation through the azygous continuation in a patient with inferior vena cava interruption. (21030393)
2011
4
Deep vein thrombosis, inferior vena cava interruption and multiple thrombophilic gene mutations. (21642818)
2011
5
Infrahepatic caudal/inferior vena cava interruption with azygos/hemiazygos continuation. Vascular anomaly in swine. (22933907)
2010
6
Pulmonary embolism associated with inferior vena cava interruption: multidetector computed tomography findings. (20498625)
2010
7
Radiofrequency ablation of atrioventricular nodal tachycardia in a patient with dextrocardia, inferior vena cava interruption, and azygos continuation. (18031517)
2008
8
Catheter ablation of left free wall accessory pathway in a patient with inferior vena cava interruption. (12674185)
2002
9
Inferior vena cava interruption: how and when? (10774449)
2000
10
Inferior vena cava interruption with renal vein collar continuation: CT and MRI appearance. (1773417)
1991
11
The Vena Tech filter: evaluation of a new inferior vena cava interruption device. (1939334)
1991
12
Inferior vena cava interruption with the Hunter-Sessions balloon: eighteen years' experience in 191 cases. (2795770)
1989
13
Transvenous devices for inferior vena cava interruption. (2585660)
1989
14
Recurrent, fatal pulmonary embolism despite inferior vena cava interruption with the Greenfield filter. (3577368)
1987
15
Inferior vena cava interruption. (3874355)
1985
16
Inferior vena cava interruption in the management of pulmonary embolism. (7140404)
1982
17
Requirements for a method of transvenous inferior vena cava interruption. (7436725)
1980
18
Diagnosis of pulmonary embolism: correlation of value of perfusion lung scan and pulmonary arteriography in selecting patients for inferior vena cava interruption. (637417)
1978
19
Inferior vena cava interruption: a new indication? (1164184)
1975
20
Fatal complications following inferior vena cava interruption. (5159420)
1971

Variations for Inferior Vena Cava Interruption

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Expression for genes affiliated with Inferior Vena Cava Interruption

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Expression patterns in normal tissues for genes affiliated with Inferior Vena Cava Interruption

Search GEO for disease gene expression data for Inferior Vena Cava Interruption.

Pathways for genes affiliated with Inferior Vena Cava Interruption

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Pathways related to Inferior Vena Cava Interruption according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3F5, SERPINE1
2
Show member pathways
Complement Activation, Classical Pathway37
Complement and Coagulation Cascades37
9.3F5, SERPINE1
3
Show member pathways
9.3F5, SERPINE1
4
Show member pathways
thioredoxin pathway37
9.1MTHFR, SERPINE1

Compounds for genes affiliated with Inferior Vena Cava Interruption

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Compounds related to Inferior Vena Cava Interruption according to GeneCards/GeneDecks:

(show all 47)
idCompoundScoreTop Affiliating Genes
1batroxobin449.8SERPINE1, F5
2ancrod449.8F5, SERPINE1
3tibolone449.7SERPINE1, F5
4cyproteroneacetate449.7F5, SERPINE1
5desmopressin44 61 28 1112.7F5, SERPINE1
6hirudin449.7F5, SERPINE1
7protamine449.7SERPINE1, F5
8mycophenolate mofetil44 50 1111.7F5, SERPINE1
9raloxifene44 50 28 1112.7F5, SERPINE1
10kininogen449.7SERPINE1, F5
11pge1449.7F5, SERPINE1
12aprotinin44 1110.6F5, SERPINE1
13progestin449.6SERPINE1, F5
14sodium dodecylsulfate449.6F5, SERPINE1
15atorvastatin44 50 28 24 1113.6F5, SERPINE1
16simvastatin44 50 61 28 24 1114.6F5, SERPINE1
17endotoxin449.5SERPINE1, F5
18p00001449.5SERPINE1, MTHFR
19prostacyclin449.5F5, SERPINE1
205-methyltetrahydrofolate44 1110.5MTHFR, F5
21cystathionine449.5F5, MTHFR
22pravastatin44 50 28 24 1113.4MTHFR, SERPINE1
23vitamin b6449.4F5, MTHFR
24tacrolimus44 50 1111.4F5, SERPINE1
25warfarin44 50 24 1112.4F5, MTHFR
26vitamin b12449.4F5, MTHFR
27p002449.3MTHFR, F5
28adenine44 24 1111.3F5, MTHFR
29folate449.2F5, MTHFR
30vitamin d449.1MTHFR, SERPINE1
31guanine44 24 1111.0F5, MTHFR
32methotrexate50 44 1111.0SERPINE1, MTHFR
33metformin44 50 1111.0F5, MTHFR, SERPINE1
34uric acid44 2410.0F5, MTHFR, SERPINE1
35homocysteine44 249.9SERPINE1, MTHFR, F5
36cyclophosphamide44 50 1110.9F5, MTHFR, SERPINE1
37aspirin44 50 28 2411.9F5, MTHFR, SERPINE1
38fibrinogen448.9F5, MTHFR, SERPINE1
39creatinine448.9F5, MTHFR, SERPINE1
40aspartate448.9SERPINE1, MTHFR, F5
41heparin44 28 24 1111.9F5, MTHFR, SERPINE1
42testosterone44 61 24 1111.9SERPINE1, MTHFR, F5
43cholesterol44 28 24 1111.9F5, MTHFR, SERPINE1
44estrogen448.8F5, MTHFR, SERPINE1
45retinoic acid44 249.8SERPINE1, MTHFR, F5
46ascorbic acid44 249.7F5, MTHFR
47serine448.6SERPINE1, MTHFR, F5

GO Terms for genes affiliated with Inferior Vena Cava Interruption

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Cellular components related to Inferior Vena Cava Interruption according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:0310939.3F5, SERPINE1

Biological processes related to Inferior Vena Cava Interruption according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet activationGO:0301689.3F5, SERPINE1
2platelet degranulationGO:0025769.0F5, SERPINE1
3blood circulationGO:0080158.9F5, MTHFR

Products for genes affiliated with Inferior Vena Cava Interruption

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  • Antibodies
  • Proteins
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Sources for Inferior Vena Cava Interruption

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet