MCID: INF133
MIFTS: 29

Inferior Vena Cava Interruption

Categories: Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Inferior Vena Cava Interruption

MalaCards integrated aliases for Inferior Vena Cava Interruption:

Name: Inferior Vena Cava Interruption 56
Inferior Caval Vein Interruption 56
Ivc Interruption 56

Classifications:



External Ids:

Orphanet 56 ORPHA99123
ICD10 via Orphanet 34 Q26.8

Summaries for Inferior Vena Cava Interruption

MalaCards based summary : Inferior Vena Cava Interruption, also known as inferior caval vein interruption, is related to pulmonary embolism and stoll alembik finck syndrome. An important gene associated with Inferior Vena Cava Interruption is F5 (Coagulation Factor V), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. The drugs Kava and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include kidney, lung and liver, and related phenotype is integument.

Related Diseases for Inferior Vena Cava Interruption

Diseases related to Inferior Vena Cava Interruption via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
id Related Disease Score Top Affiliating Genes
1 pulmonary embolism 10.2
2 stoll alembik finck syndrome 10.1 F5 SERPINE1
3 collagenous colitis 10.1 F5 SERPINE1
4 retinal dystrophy, iris coloboma, and comedogenic acne syndrome 10.1 F5 SERPINE1
5 mental retardation dysmorphism hypogonadism diabetes 10.1 F5 SERPINE1
6 neuroaxonal dystrophy 10.1 F5 SERPINE1
7 stickler sydrome, type i, nonsyndromic ocular 10.1 F5 SERPINE1
8 inherited blood coagulation disease 10.1 F5 SERPINE1
9 neuromyelitis optica 9.9 MTHFR SERPINE1
10 elejalde disease 9.9 MTHFR SERPINE1
11 arcus senilis 9.9 MTHFR SERPINE1
12 thrombosis 9.9
13 heart disease 9.9
14 dextrocardia 9.9
15 double inferior vena cava 9.9
16 brill-zinsser disease 9.9 F5 SERPINE1
17 multicentric osteolysis nephropathy 9.9 F5 MTHFR
18 capillary hemangioma 9.9 MTHFR SERPINE1
19 syncope 9.8 F5 MTHFR
20 superior limbic keratoconjunctivitis 9.8 F5 MTHFR
21 follicular adenoma 9.8 F5 MTHFR
22 pregnancy loss, recurrent 1 9.8 F5 MTHFR
23 hiv-1 9.8 F5 MTHFR
24 primary pigmented nodular adrenocortical disease 9.8 F5 MTHFR
25 femoral neuropathy 9.8 F5 MTHFR
26 cryptosporidiosis 9.8 F5 MTHFR
27 homologous wasting disease 9.8 F5 MTHFR
28 angular blepharoconjunctivitis 9.8 F5 MTHFR
29 hepatocellular adenoma 9.8 F5 MTHFR
30 ulcerative stomatitis 9.7 F5 MTHFR
31 blepharoconjunctivitis 9.7 F5 MTHFR
32 ovarian insufficiency, familial 9.7 MTHFR SERPINE1
33 schizencephaly 9.7 F5 MTHFR
34 aryepiglottic fold cancer 9.7 F5 MTHFR
35 thrombomodulin anomalies, familial 9.7 F5 MTHFR
36 joint disorders 9.7 F5 MTHFR
37 leukorrhea 9.7 F5 MTHFR
38 ocular hyperemia 9.7 F5 MTHFR
39 necrotic uveal melanoma 9.6 F5 MTHFR
40 budd-chiari syndrome 9.6 F5 MTHFR
41 mixed germ cell-sex cord neoplasm 9.6 F5 MTHFR
42 dentine erosion 9.5 F5 MTHFR
43 macular degeneration, age-related, 12 9.5 MTHFR SERPINE1
44 charcot-marie-tooth disease 9.5 F5 MTHFR
45 primary cerebellar degeneration 9.4 F5 MTHFR
46 pleural tuberculosis 9.4 MTHFR SERPINE1
47 coronary sinus stenosis 9.4 F5 MTHFR SERPINE1
48 amelogenesis imperfecta hypomaturation type 9.4 F5 MTHFR SERPINE1
49 lockwood feingold syndrome 9.4 F5 MTHFR SERPINE1
50 cavernous lymphangioma 9.4 F5 MTHFR SERPINE1

Graphical network of the top 20 diseases related to Inferior Vena Cava Interruption:



Diseases related to Inferior Vena Cava Interruption

Symptoms & Phenotypes for Inferior Vena Cava Interruption

MGI Mouse Phenotypes related to Inferior Vena Cava Interruption:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.8 F5 MTHFR SERPINE1

Drugs & Therapeutics for Inferior Vena Cava Interruption

Drugs for Inferior Vena Cava Interruption (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Kava Nutraceutical Phase 4 9000-38-8
2
Epinephrine Approved, Vet_approved 51-43-4 5816
3 Racepinephrine Approved
4 Respiratory System Agents
5 Adrenergic Agents
6 Adrenergic Agonists
7 Adrenergic alpha-Agonists
8 Adrenergic beta-Agonists
9 Mydriatics
10 Neurotransmitter Agents
11 Vasoconstrictor Agents
12 Anti-Asthmatic Agents
13 Peripheral Nervous System Agents
14 Epinephryl borate
15 Autonomic Agents
16 Bronchodilator Agents

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 PREPIC 2 : Prevention of Recurrent Pulmonary Embolism by Vena Cava Interruption Completed NCT00457158 Phase 4
2 Defining Immunodeficiency in Heterotaxy Syndrome: Pilot Study Data Completed NCT01929967
3 A Prospective, Multi-Center Study of the Bard® Denali™ Retrievable Inferior Vena Cava Filter System Completed NCT01305564
4 RexMedical- Option* Vena Cava Filter IDE Study Completed NCT00488865
5 Prospective, Multi-center, Single-arm Study to Assess the Safety of Retrieval of the Recovery G2 Filter. Completed NCT00556426
6 Adrenal Function After Living Kidney Donation Completed NCT00251836

Search NIH Clinical Center for Inferior Vena Cava Interruption

Genetic Tests for Inferior Vena Cava Interruption

Anatomical Context for Inferior Vena Cava Interruption

MalaCards organs/tissues related to Inferior Vena Cava Interruption:

39
Kidney, Lung, Liver, Heart

Publications for Inferior Vena Cava Interruption

Articles related to Inferior Vena Cava Interruption:

(show all 21)
id Title Authors Year
1
Catheter ablation of atrial arrhythmias in a patient with surgically corrected congenital heart disease and inferior vena cava interruption. ( 26136634 )
2015
2
Transapical closure of paraprosthetic mitral leak in a patient with inferior vena cava interruption and azygos continuation. ( 24048023 )
2013
3
Inferior vena cava interruption in a liver transplantation deceased donor. ( 23230844 )
2013
4
Atrial flutter ablation through the azygous continuation in a patient with inferior vena cava interruption. ( 21030393 )
2011
5
Deep vein thrombosis, inferior vena cava interruption and multiple thrombophilic gene mutations. ( 21642818 )
2011
6
Infrahepatic caudal/inferior vena cava interruption with azygos/hemiazygos continuation. Vascular anomaly in swine. ( 22933907 )
2010
7
Pulmonary embolism associated with inferior vena cava interruption: multidetector computed tomography findings. ( 20498625 )
2010
8
Radiofrequency ablation of atrioventricular nodal tachycardia in a patient with dextrocardia, inferior vena cava interruption, and azygos continuation. ( 18031517 )
2008
9
Catheter ablation of left free wall accessory pathway in a patient with inferior vena cava interruption. ( 12674185 )
2002
10
Inferior vena cava interruption: how and when? ( 10774449 )
2000
11
The Vena Tech filter: evaluation of a new inferior vena cava interruption device. ( 1939334 )
1991
12
Inferior vena cava interruption with renal vein collar continuation: CT and MRI appearance. ( 1773417 )
1991
13
Transvenous devices for inferior vena cava interruption. ( 2585660 )
1989
14
Inferior vena cava interruption with the Hunter-Sessions balloon: eighteen years' experience in 191 cases. ( 2795770 )
1989
15
Recurrent, fatal pulmonary embolism despite inferior vena cava interruption with the Greenfield filter. ( 3577368 )
1987
16
Inferior vena cava interruption. ( 3874355 )
1985
17
Inferior vena cava interruption in the management of pulmonary embolism. ( 7140404 )
1982
18
Requirements for a method of transvenous inferior vena cava interruption. ( 7436725 )
1980
19
Diagnosis of pulmonary embolism: correlation of value of perfusion lung scan and pulmonary arteriography in selecting patients for inferior vena cava interruption. ( 637417 )
1978
20
Inferior vena cava interruption: a new indication? ( 1164184 )
1975
21
Fatal complications following inferior vena cava interruption. ( 5159420 )
1971

Variations for Inferior Vena Cava Interruption

Expression for Inferior Vena Cava Interruption

Search GEO for disease gene expression data for Inferior Vena Cava Interruption.

Pathways for Inferior Vena Cava Interruption

GO Terms for Inferior Vena Cava Interruption

Cellular components related to Inferior Vena Cava Interruption according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 8.62 F5 SERPINE1

Biological processes related to Inferior Vena Cava Interruption according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 8.96 F5 SERPINE1
2 blood circulation GO:0008015 8.62 F5 MTHFR

Sources for Inferior Vena Cava Interruption

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....