MCID: INF133
MIFTS: 28

Inferior Vena Cava Interruption

Categories: Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Inferior Vena Cava Interruption

MalaCards integrated aliases for Inferior Vena Cava Interruption:

Name: Inferior Vena Cava Interruption 55
Inferior Caval Vein Interruption 55
Ivc Interruption 55

Classifications:



External Ids:

Orphanet 55 ORPHA99123
ICD10 via Orphanet 33 Q26.8

Summaries for Inferior Vena Cava Interruption

MalaCards based summary : Inferior Vena Cava Interruption, also known as inferior caval vein interruption, is related to pulmonary embolism and thrombosis. An important gene associated with Inferior Vena Cava Interruption is F5 (Coagulation Factor V), and among its related pathways/superpathways are Selenium Micronutrient Network and Formation of Fibrin Clot (Clotting Cascade). The drug Kava has been mentioned in the context of this disorder. Affiliated tissues include lung, liver and heart, and related phenotype is integument.

Related Diseases for Inferior Vena Cava Interruption

Diseases related to Inferior Vena Cava Interruption via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 pulmonary embolism 29.6 F5 MTHFR SERPINE1
2 thrombosis 29.2 F5 MTHFR SERPINE1
3 dextrocardia 10.1
4 sticky platelet syndrome 10.1 F5 SERPINE1
5 ischemic colitis 10.0 F5 SERPINE1
6 meningococcemia 10.0 F5 SERPINE1
7 quebec platelet disorder 10.0 F5 SERPINE1
8 factor xiii deficiency 10.0 F5 SERPINE1
9 post-thrombotic syndrome 10.0 F5 SERPINE1
10 legg-calve-perthes disease 10.0 F5 SERPINE1
11 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 10.0
12 heart disease 10.0
13 double inferior vena cava 10.0
14 neonatal stroke 9.9 MTHFR SERPINE1
15 disseminated intravascular coagulation 9.9 F5 SERPINE1
16 buerger disease 9.9 MTHFR SERPINE1
17 lemierre's syndrome 9.9 MTHFR SERPINE1
18 hepatic vascular disease 9.9 MTHFR SERPINE1
19 spinal cord infarction 9.8 F5 MTHFR
20 sudden sensorineural hearing loss 9.8 F5 MTHFR
21 pregnancy loss, recurrent 1 9.8 F5 MTHFR
22 porencephaly 9.8 F5 MTHFR
23 retinal vascular occlusion 9.8 F5 MTHFR
24 intracranial thrombosis 9.8 F5 MTHFR
25 antithrombin iii deficiency 9.8 F5 MTHFR
26 central retinal vein occlusion 9.8 F5 MTHFR
27 arteritic anterior ischemic optic neuropathy 9.8 F5 MTHFR
28 osteonecrosis 9.8 MTHFR SERPINE1
29 protein s deficiency 9.8 F5 MTHFR
30 vein disease 9.8 F5 MTHFR
31 placental abruption 9.8 F5 MTHFR
32 thrombasthenia 9.8 F5 MTHFR
33 schizencephaly 9.8 F5 MTHFR
34 ischemic optic neuropathy 9.8 F5 MTHFR
35 protein c deficiency 9.7 F5 MTHFR
36 blood coagulation disease 9.7 F5 MTHFR
37 nonarteritic anterior ischemic optic neuropathy 9.7 F5 MTHFR
38 placenta disease 9.7 F5 MTHFR
39 budd-chiari syndrome 9.7 F5 MTHFR
40 varicose veins 9.7 F5 MTHFR
41 antiphospholipid syndrome 9.7 F5 MTHFR
42 hemorrhagic disease 9.7 F5 SERPINE1
43 patent foramen ovale 9.6 F5 MTHFR
44 cerebral palsy 9.6 F5 MTHFR
45 homocystinuria 9.6 F5 MTHFR
46 arteries, anomalies of 9.6 MTHFR SERPINE1
47 eclampsia 9.6 F5 MTHFR
48 amaurosis fugax 9.5 F5 MTHFR SERPINE1
49 livedoid vasculopathy 9.5 F5 MTHFR SERPINE1
50 cryptogenic cirrhosis 9.5 F5 MTHFR SERPINE1

Graphical network of the top 20 diseases related to Inferior Vena Cava Interruption:



Diseases related to Inferior Vena Cava Interruption

Symptoms & Phenotypes for Inferior Vena Cava Interruption

MGI Mouse Phenotypes related to Inferior Vena Cava Interruption:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.8 F5 MTHFR SERPINE1

Drugs & Therapeutics for Inferior Vena Cava Interruption

Drugs for Inferior Vena Cava Interruption (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Kava Approved, Investigational, Nutraceutical 9000-38-8

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Defining Immunodeficiency in Heterotaxy Syndrome: Pilot Study Data Completed NCT01929967

Search NIH Clinical Center for Inferior Vena Cava Interruption

Genetic Tests for Inferior Vena Cava Interruption

Anatomical Context for Inferior Vena Cava Interruption

MalaCards organs/tissues related to Inferior Vena Cava Interruption:

38
Lung, Liver, Heart

Publications for Inferior Vena Cava Interruption

Articles related to Inferior Vena Cava Interruption:

(show all 23)
# Title Authors Year
1
Management of scar-related atrial flutter in a patient with dextrocardia, inferior vena cava interruption, and azygos continuation. ( 29424736 )
2018
2
Catheter ablation of typical atrial flutter with the superior approach in a patient with inferior vena cava interruption. ( 29152281 )
2017
3
Catheter ablation of atrial arrhythmias in a patient with surgically corrected congenital heart disease and inferior vena cava interruption. ( 26136634 )
2015
4
Inferior vena cava interruption in a liver transplantation deceased donor. ( 23230844 )
2013
5
Transapical closure of paraprosthetic mitral leak in a patient with inferior vena cava interruption and azygos continuation. ( 24048023 )
2013
6
Atrial flutter ablation through the azygous continuation in a patient with inferior vena cava interruption. ( 21030393 )
2011
7
Deep vein thrombosis, inferior vena cava interruption and multiple thrombophilic gene mutations. ( 21642818 )
2011
8
Infrahepatic caudal/inferior vena cava interruption with azygos/hemiazygos continuation. Vascular anomaly in swine. ( 22933907 )
2010
9
Pulmonary embolism associated with inferior vena cava interruption: multidetector computed tomography findings. ( 20498625 )
2010
10
Radiofrequency ablation of atrioventricular nodal tachycardia in a patient with dextrocardia, inferior vena cava interruption, and azygos continuation. ( 18031517 )
2008
11
Catheter ablation of left free wall accessory pathway in a patient with inferior vena cava interruption. ( 12674185 )
2002
12
Inferior vena cava interruption: how and when? ( 10774449 )
2000
13
The Vena Tech filter: evaluation of a new inferior vena cava interruption device. ( 1939334 )
1991
14
Inferior vena cava interruption with renal vein collar continuation: CT and MRI appearance. ( 1773417 )
1991
15
Transvenous devices for inferior vena cava interruption. ( 2585660 )
1989
16
Inferior vena cava interruption with the Hunter-Sessions balloon: eighteen years' experience in 191 cases. ( 2795770 )
1989
17
Recurrent, fatal pulmonary embolism despite inferior vena cava interruption with the Greenfield filter. ( 3577368 )
1987
18
Inferior vena cava interruption. ( 3874355 )
1985
19
Inferior vena cava interruption in the management of pulmonary embolism. ( 7140404 )
1982
20
Requirements for a method of transvenous inferior vena cava interruption. ( 7436725 )
1980
21
Diagnosis of pulmonary embolism: correlation of value of perfusion lung scan and pulmonary arteriography in selecting patients for inferior vena cava interruption. ( 637417 )
1978
22
Inferior vena cava interruption: a new indication? ( 1164184 )
1975
23
Fatal complications following inferior vena cava interruption. ( 5159420 )
1971

Variations for Inferior Vena Cava Interruption

Expression for Inferior Vena Cava Interruption

Search GEO for disease gene expression data for Inferior Vena Cava Interruption.

Pathways for Inferior Vena Cava Interruption

GO Terms for Inferior Vena Cava Interruption

Cellular components related to Inferior Vena Cava Interruption according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 8.62 F5 SERPINE1

Biological processes related to Inferior Vena Cava Interruption according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet degranulation GO:0002576 8.96 F5 SERPINE1
2 blood circulation GO:0008015 8.62 F5 MTHFR

Sources for Inferior Vena Cava Interruption

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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