MCID: INF037
MIFTS: 44

Inflammatory Bowel Disease malady

Summaries for Inflammatory Bowel Disease

Sources:
3CDC, 64Wikipedia, 47OMIM, 33MalaCards
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CDC:3 Inflammatory Bowel Diseases (IBD) is a broad term that describes conditions with chronic or recurring immune response and inflammation of the gastrointestinal tract. The two most common inflammatory bowel diseases are ulcerative colitis and Crohn’s disease.

MalaCards: Inflammatory Bowel Disease, also known as inflammatory bowel diseases, is related to ulcerative colitis and crohn's disease. An important gene associated with Inflammatory Bowel Disease is NOD2 (nucleotide-binding oligomerization domain containing 2). The drugs cromolyn sodium and cromolyn have been mentioned in the context of this disorder.

Wikipedia:64 In medicine, inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and... more...

Description from OMIM:47 612244, 612245, 613148, 611081, 266600 612261, 612567 more

Aliases & Classifications for Inflammatory Bowel Disease

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 47OMIM
See all sources

Aliases & Descriptions:

inflammatory bowel disease 8 10
inflammatory bowel diseases 45 61


External Ids:

Disease Ontology8 DOID:0050589

Related Diseases for Inflammatory Bowel Disease

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Inflammatory Bowel Disease family:

inflammatory bowel disease 7 inflammatory bowel disease 23
inflammatory bowel disease 10 inflammatory bowel disease 9
inflammatory bowel disease 12 inflammatory bowel disease 18
inflammatory bowel disease 5 inflammatory bowel disease 19
inflammatory bowel disease 3 inflammatory bowel disease 13
inflammatory bowel disease 11 inflammatory bowel disease 14
inflammatory bowel disease 16 inflammatory bowel disease 15
inflammatory bowel disease 20 inflammatory bowel disease 2
inflammatory bowel disease 26 inflammatory bowel disease 27
inflammatory bowel disease 4 inflammatory bowel disease 8
inflammatory bowel disease 1 inflammatory bowel disease 22
inflammatory bowel disease 21 inflammatory bowel disease 6
inflammatory bowel disease 24

Diseases related to Inflammatory Bowel Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 236)
idRelated DiseaseScoreTop Affiliating Genes
1ulcerative colitis31.3NOD2, ATG16L1
2crohn's disease31.1NOD2, ATG16L1
3inflammatory bowel disease 110.9
4primary sclerosing cholangitis10.8
5sclerosing cholangitis10.8
6inflammatory bowel disease 210.8
7pyoderma gangrenosum10.7
8irritable bowel syndrome10.7
9colorectal cancer10.7
10lip disease10.7
11vascular disease10.7
12deficiency anemia10.6
13iron deficiency anemia10.6
14hepatitis b10.6
15hepatitis d10.6
16inflammatory bowel disease 2010.6
17inflammatory bowel disease 1910.6
18nutrition disease10.6
19celiac disease10.5
20osteoporosis10.5
21clostridium difficile10.5
22thromboembolism10.5
23inflammatory bowel disease 1010.5
24inflammatory bowel disease 310.5
25venous thrombosis10.5
26pouchitis10.5
27tuberculosis10.5
28inflammatory bowel disease 1210.5
29hepatitis c10.5
30ankylosing spondylitis10.5
31arthritis10.5
32spondylitis10.5
33spondyloarthropathy10.5
34collagenous colitis10.5
35nodular regenerative hyperplasia10.5
36inflammatory bowel disease 810.5
37proctitis10.5
38n syndrome10.5
39hepatitis a10.5
40inflammatory bowel disease 710.5
41inflammatory bowel disease 1110.5
42venous thromboembolism10.5
43fecal incontinence10.4
44hyperhomocysteinemia10.4
45thrombophilia10.4
46vein disease10.4
47pediatric ulcerative colitis10.4
48inflammatory bowel disease 2310.4
49inflammatory bowel disease 1510.4
50inflammatory bowel disease 2610.4

Graphical network of the top 20 diseases related to Inflammatory Bowel Disease:



Diseases related to inflammatory bowel disease

Clinical Features for Inflammatory Bowel Disease

Sources:
47OMIM
See all sources

Clinical features from OMIM:

612244,612245,613148,611081,266600,612261,612567

Drugs & Therapeutics for Inflammatory Bowel Disease

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Inflammatory Bowel Disease

Drug clinical trials:

Search ClinicalTrials for Inflammatory Bowel Disease

Search NIH Clinical Center for Inflammatory Bowel Disease

Search CenterWatch for Inflammatory Bowel Disease

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Inflammatory Bowel Disease

Anatomical Context for Inflammatory Bowel Disease

Animal Models for Inflammatory Bowel Disease or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Inflammatory Bowel Disease

Sources:
51PubMed
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Articles related to Inflammatory Bowel Disease:

(show top 50)    (show all 2301)
idTitleAuthorsYear
1
Healing under pressure: hyperbaric oxygen and myocutaneous flap repair for extreme persistent perineal sinus after proctectomy for inflammatory bowel disease. (24267200)
2013
2
Dermatologist and gastroenterologist awareness of the potential of immunosuppressants used to treat inflammatory bowel disease to cause non-melanoma skin cancer. (23556532)
2013
3
Tissue IgG4-positive plasma cells in inflammatory bowel disease: a study of 88 treatment-naive biopsies of inflammatory bowel disease. (23929268)
2013
4
Granulocyte macrophage colony-stimulating factor auto-antibodies and disease relapse in inflammatory bowel disease. (24145675)
2013
5
Focally enhanced gastritis in newly diagnosed pediatric inflammatory bowel disease. (24121177)
2013
6
Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling. (24155895)
2013
7
The impact of abdominal computed tomography in a tertiary referral centre emergency department on the management of patients with inflammatory bowel disease. (23837741)
2013
8
A tale of two diseases: The history of inflammatory bowel disease. (24094598)
2013
9
Anti-GP2 antibodies in inflammatory bowel disease patients with ileal pouch. (23845232)
2013
10
Hepcidin and its role in inflammatory bowel disease. (23986220)
2013
11
Granulocytapheresis in steroid-dependent and steroid-resistant patients with inflammatory bowel disease: a prospective observational study. (23870727)
2013
12
Inflammatory skin and bowel disease linked to ADAM17 deletion. (22010916)
2011
13
Association of caspase-9 and RUNX3 with inflammatory bowel disease. (20887385)
2011
14
Small bowel obstruction secondary to pelvic inflammatory disease. (21679543)
2011
15
Colon bleeding from both arteriovenous malformation and inflammatory bowel disease. Case report. (22018216)
2011
16
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. (21830270)
2011
17
Relationships between genetic polymorphisms of triggering receptor expressed on myeloid cells-1 and inflammatory bowel diseases in the Korean population. (21763322)
2011
18
Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women. (19294505)
2010
19
Higher levels of CCL20 expression on peripheral blood mononuclear cells of chinese patients with inflammatory bowel disease. (20064082)
2010
20
Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. (19098859)
2009
21
Fecal lactoferrin is a sensitive and specific marker of disease activity in children and young adults with inflammatory bowel disease. (17414136)
2007
22
Replication of an association between IL23R gene polymorphism with inflammatory bowel disease. (17678845)
2007
23
Enzymes in feces: useful markers of chronic inflammatory bowel disease. (17368600)
2007
24
N-acetyltransferase 2 slow acetylator genotype associated with adverse effects of sulphasalazine in the treatment of inflammatory bowel disease. (17377643)
2007
25
Intestinal helminths: a clue explaining the low incidence of inflammatory bowel diseases in Subsaharan Africa? Potential benefits and hazards of helminth therapy. (17343086)
2006
26
Absence of association between the multidrug resistance (MDR1) gene and inflammatory bowel disease. (16990202)
2006
27
TPMT genotype and the use of thiopurines in paediatric inflammatory bowel disease. (16202677)
2005
28
The RANKL/OPG system is activated in inflammatory bowel disease and relates to the state of bone loss. (15753532)
2005
29
Kallikrein-kinin system in inflammatory bowel diseases: Intestinal involvement and correlation with the degree of tissue inflammation. (15949977)
2005
30
Review article: bone disease in inflammatory bowel disease. (15352893)
2004
31
Interventions for treating collagenous colitis: a Cochrane Inflammatory Bowel Disease Group systematic review of randomized trials. (15571596)
2004
32
Effects of dermatan sulfate derivatives on platelet surface P-selectin expression and protein C activity in blood of inflammatory bowel disease patients. (15526370)
2004
33
The epithelium in inflammatory bowel disease: potential role of endocytosis of junctional proteins in barrier disruption. (15669638)
2004
34
Tumour necrosis factor-alpha receptor 1 and 2 polymorphisms in inflammatory bowel disease and their association with response to infliximab. (15274667)
2004
35
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease. (14568967)
2003
36
Optimizing immunomodulator therapy for inflammatory bowel disease. (14602061)
2003
37
Linkage of ulcerative colitis to the pericentromeric region of chromosome 16 in Italian inflammatory bowel disease families is independent of the presence of common CARD15 mutations. (14627676)
2003
38
Osteoporosis and inflammatory bowel disease: prevalence and risk factors in Tunisian patients]. (14631305)
2003
39
Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease. (12169983)
2002
40
Circulating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease. (10749795)
2000
41
Inflammatory bowel disease: progress toward a gene. (10758418)
2000
42
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. (11083826)
2000
43
Analysis of Australian Crohn's disease pedigrees refines the localization for susceptibility to inflammatory bowel disease on chromosome 16. (9924607)
1998
44
Medical therapy of inflammatory bowel disease for the 21st century. (10029372)
1998
45
Contribution of the IL-2 and IL-10 genes to inflammatory bowel disease (IBD) susceptibility. (9697979)
1998
46
Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease. (8592524)
1996
47
Insulin-like growth factors and inflammatory bowel disease. (8732302)
1996
48
Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR). (7664489)
1995
49
Tumor necrosis factor and IL-1 beta expression in pediatric patients with inflammatory bowel disease. (8492249)
1993
50
Significance of interleukin-6 in patients with inflammatory bowel disease. (2007457)
1991

Genetic Variations for Inflammatory Bowel Disease

Expression for genes affiliated with Inflammatory Bowel Disease

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Inflammatory Bowel Disease

Search GEO for disease gene expression data for Inflammatory Bowel Disease.

Pathways for genes affiliated with Inflammatory Bowel Disease

Compounds for genes affiliated with Inflammatory Bowel Disease

GO Terms for genes affiliated with Inflammatory Bowel Disease

Sources:
16Gene Ontology
See all sources

Biological processes related to Inflammatory Bowel Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1stress-activated MAPK cascadeGO:05140310.8NOD2, AGT

Products for genes affiliated with Inflammatory Bowel Disease

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  • Antibodies

Sources for Inflammatory Bowel Disease

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet