MCID: INF002
MIFTS: 23

Inflammatory Diarrhea

Categories: Rare diseases, Gastrointestinal diseases, Genetic diseases

Aliases & Classifications for Inflammatory Diarrhea

MalaCards integrated aliases for Inflammatory Diarrhea:

Name: Inflammatory Diarrhea 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0050132
UMLS 69 C0521604

Summaries for Inflammatory Diarrhea

Disease Ontology : 12 A gastrointestinal system infectious disease involving diarrhea that occurs when there is damage to the mucosal lining or brush border, which leads to a passive loss of protein-rich fluids, and a decreased ability to absorb these lost fluids. It can be caused by bacterial infections, viral infections, parasitic infections, or autoimmune problems such as inflammatory bowel diseases. It can also be caused by tuberculosis, colon cancer, and enteritis.

MalaCards based summary : Inflammatory Diarrhea is related to diarrhea and poikiloderma with neutropenia. An important gene associated with Inflammatory Diarrhea is PITX1 (Paired Like Homeodomain 1), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Affiliated tissues include colon.

Related Diseases for Inflammatory Diarrhea

Graphical network of the top 20 diseases related to Inflammatory Diarrhea:



Diseases related to Inflammatory Diarrhea

Symptoms & Phenotypes for Inflammatory Diarrhea

Drugs & Therapeutics for Inflammatory Diarrhea

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Epidemiology of Chronic Diarrhea Among Children Admitted to Gastroenterology Unit at Assuit University Children Hospital Recruiting NCT03261297

Search NIH Clinical Center for Inflammatory Diarrhea

Genetic Tests for Inflammatory Diarrhea

Anatomical Context for Inflammatory Diarrhea

MalaCards organs/tissues related to Inflammatory Diarrhea:

38
Colon

Publications for Inflammatory Diarrhea

Articles related to Inflammatory Diarrhea:

# Title Authors Year
1
Different Age Distribution between Campylobacteriosis and Nontyphoidal Salmonellosis in Hospitalized Korean Children with Acute Inflammatory Diarrhea. ( 28581280 )
2017
2
Inflammatory diarrhea due to enteroaggregative Escherichia coli: evidence from clinical and mice model studies. ( 24294997 )
2013
3
Serum C-reactive protein (CRP) levels in young adults can be used to discriminate between inflammatory and non-inflammatory diarrhea. ( 22926497 )
2013
4
Human enteroids: preclinical models of non-inflammatory diarrhea. ( 24564938 )
2013
5
Diarrhea. Enterotoxigenic Bacteroides fragilis: newly recognized cause of inflammatory diarrhea. ( 19678432 )
2009
6
Association of enterotoxigenic Bacteroides fragilis infection with inflammatory diarrhea. ( 18680416 )
2008
7
Dangers of empiric oral ciprofloxacin in the treatment of acute inflammatory diarrhea in children. ( 11734755 )
2001
8
Mechanisms of inflammatory diarrhea. ( 1634090 )
1992
9
Clinical and immunologic significance of cholera-like toxin and cytotoxin production by Campylobacter species in patients with acute inflammatory diarrhea in the USA. ( 2760498 )
1989
10
Kawasaki disease presenting in an adult as inflammatory diarrhea. ( 3509115 )
1987

Variations for Inflammatory Diarrhea

Expression for Inflammatory Diarrhea

Search GEO for disease gene expression data for Inflammatory Diarrhea.

Pathways for Inflammatory Diarrhea

Pathways related to Inflammatory Diarrhea according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.6 CXCL8 MPO SPI1
2 11.34 CXCL8 SLC9A3 VIPR1
3 11.15 MPO SPI1
4 10.71 CXCL8 SPI1 VIPR1

GO Terms for Inflammatory Diarrhea

Molecular functions related to Inflammatory Diarrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II transcription factor binding GO:0001085 8.62 PITX1 SPI1

Sources for Inflammatory Diarrhea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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