MCID: INF058
MIFTS: 42

Inflammatory Myofibroblastic Tumor malady

Rare diseases, Cancer diseases categories

Aliases & Classifications for Inflammatory Myofibroblastic Tumor

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 65UMLS, 47Novoseek, 66UMLS via Orphanet
See all sources

Aliases & Descriptions for Inflammatory Myofibroblastic Tumor:

Name: Inflammatory Myofibroblastic Tumor 10 45 12 51 65
Inflammatory Fibrosarcoma 45
 
Inflammatory Pseudotumor 45
Pseudotumor Inflammatory 47


Classifications:

Orphanet: 51 
Rare tumors


External Ids:

Disease Ontology10 DOID:0050905
Orphanet51 178342
UMLS via Orphanet66 C0334121

Summaries for Inflammatory Myofibroblastic Tumor

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NIH Rare Diseases:45 An inflammatory myofibroblastic tumor (imt) is an uncommon, presumably benign (non-cancerous) tumor made up of cells called myofibroblastic spindle cells. it usually develops in children or young adults, but can affect people of any age. an imt can occur in almost any part of the body but is most commonly found in the lung, orbit (eye socket), peritoneum (lining of the abdominal cavity and internal organs), and mesentery. signs and symptoms vary depending on the site of the tumor. some people with an imt are asymptomatic, while others may have nonspecific respiratory symptoms, fever, or pain. imts may recur, and occasionally become locally invasive and/or spread (metastasize) to other parts of the body. the underlying cause of imts is poorly understood. treatment involves surgical removal when possible, although there are reports of treatment with oral steroids and radiation therapy. last updated: 10/13/2015

MalaCards based summary: Inflammatory Myofibroblastic Tumor, also known as inflammatory fibrosarcoma, is related to lymphoplasmacyte-rich meningioma and angiomyolipoma. An important gene associated with Inflammatory Myofibroblastic Tumor is ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase), and among its related pathways are Sumoylation by RanBP2 regulates transcriptional repression and Cardiac muscle contraction. Affiliated tissues include lung, eye and bone, and related mouse phenotypes are tumorigenesis and muscle.

Disease Ontology:10 A mesenchymal cell neoplasm that has material basis in myofibroblastic cells admixed with inflammatory cells.

Related Diseases for Inflammatory Myofibroblastic Tumor

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Diseases related to Inflammatory Myofibroblastic Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 251)
idRelated DiseaseScoreTop Affiliating Genes
1lymphoplasmacyte-rich meningioma30.4DES, S100B
2angiomyolipoma30.3ACTC1, DES, MDM2, VIM
3gastrointestinal stromal tumor30.0ACTC1, CCND1, DES, KIT, S100B, TP53
4cellulitis30.0ALK, CCND1, KIT, MDM2, TP53
5pancreatitis10.7
6intussusception10.6
7anaplastic large cell lymphoma10.5
8fibrosarcoma10.5
9laryngitis10.5
10cholangitis10.4
11renal cell carcinoma10.4
12esophagitis10.4
13mediastinitis10.4
14peritonitis10.4
15sarcoma10.4
16cholangiocarcinoma10.4
17lymphangiomatosis10.4ACTC1, VIM
18gastric signet ring cell adenocarcinoma10.4ACTC1, VIM
19body skin hyperlaxity due to vitamin k-dependent coagulation factor deficiency10.4S100B, VIM
20infantile free sialic acid storage disease10.4DES, VIM
21sclerosing cholangitis10.3
22follicular dendritic cell sarcoma10.3
23dendritic cell sarcoma10.3
24neonatal glycine encephalopathy10.3ACTC1, S100B
25hypersomnia10.3S100B, VIM
26necrotizing fasciitis10.3ACTC1, DES
27systemic lupus erythematosus10.3
28hepatocellular carcinoma10.3
29sinusitis10.3
30pemphigus10.3
31mastoiditis10.3
32fibroma10.3
33lupus erythematosus10.3
34meningitis10.3
35prostatitis10.3
36rhabdomyosarcoma10.3
37thyroiditis10.3
38tuberculosis10.3
39paraneoplastic pemphigus10.3
40iodine antenatal infection10.3ACTC1, VIM
41beemer ertbruggen syndrome10.3S100B, VIM
42lymphatic neoplasm10.3DES, VIM
43kidney leiomyosarcoma10.3ACTC1, DES, VIM
44signet ring basal cell carcinoma10.3ACTC1, S100B
45bladder colonic type adenocarcinoma10.3ACTC1, DES, VIM
46benign multicystic peritoneal mesothelioma10.3ACTC1, DES, VIM
47internal hemorrhoid10.3ACTC1, DES, VIM
48familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement10.3ACTC1, S100B, VIM
49infantile recurrent chronic multifocal osteomyolitis10.3ACTC1, DES, VIM
50extraneural perineurioma10.3KIT, S100B

Graphical network of the top 20 diseases related to Inflammatory Myofibroblastic Tumor:



Diseases related to inflammatory myofibroblastic tumor

Symptoms for Inflammatory Myofibroblastic Tumor

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Drugs & Therapeutics for Inflammatory Myofibroblastic Tumor

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Drugs for Inflammatory Myofibroblastic Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MechlorethamineapprovedPhase 2, Phase 341051-75-24033
Synonyms:
.Beta.,.beta.'-Dichlorodiethyl-N-methylamine
1, 5-Dichloro-3-methyl-3-azapentane hydrochloride
126-85-2 (N-oxide)
2,2'-Dichloro-N-me
2,2'-Dichloro-N-methyldiethylamine
2,2'-Dichlorodiethyl-methylamine
2,2'-dichloro-N-methyldiethylamine
2-Chloro-N-(2-chloroethyl)-N-methylethanamine
302-70-5 (N-oxide, hydrochloride)
51-75-2
55-86-7 (HYDROCHLORIDE)
AC1L1H9H
Antimit
BRN 0605323
BSPBio_001947
Bis(2-chloroethyl)methylamine
Bis(beta-chloroethyl) methylamine
Bis(beta-chloroethyl)methylamine
C07115
C5H11Cl2N
CCRIS 447
CHEBI:28925
CHEMBL427
CID4033
Carolysine
Caryolysin
Caryolysine
Chloramine (the nitrogen mustard)
Chlorethazine
Chlormethine
Chlormethine (INN)
Chlormethine [INN:BAN]
Chlormethinum [INN-Latin]
Cloramin
Clormetina
Clormetina [INN-Spanish]
D07671
DB00888
Di(2-chloroethyl)methylamine
Dichlor amine
Dichloren
DivK1c_000759
EINECS 200-120-5
ENT-25294
Embechine
Embichin
HMS1920J15
HMS2091B04
HMS502F21
HN-2
HN2
HSDB 5083
I14-8708
IBS-L0033631
IDI1_000759
KBio1_000759
KBio2_001369
KBio2_003937
KBio2_006505
KBio3_001447
KBioGR_001448
 
KBioSS_001369
LS-7559
MBA
Me chloroethamine
Mebichloramine
Mechlorethamine
Mechlorethamine hydrochloride
Mechlorethanamine
Mechloroethamine
Mecloretamina
Mecloretamina [Italian]
Methylbis(2-chloroethyl)amine
Methylbis(beta-chloroethyl)amine
Methyldi(2-chloroethyl)amine
Mitoxine (*Hydrochloride*)
MolPort-001-785-592
Mustargen
Mustine
Mustine note
Mutagen
N,N-Bis(2-chloroethyl)-N-methylamine
N,N-Bis(2-chloroethyl)methylamine
N,N-Di(chloroethyl)methylamine
N-Lost
N-Methyl lost
N-Methyl-2,2'-dichlorodiethylamine
N-Methyl-bis(2-chloroethyl)amine
N-Methyl-bis(beta-chloroethyl)amine
N-Methyl-bis-chloraethylamin
N-Methyl-bis-chloraethylamin [German]
N-Methyl-lost
N-Methyl-lost [German]
N-methyl-bis(2-chloroethyl)amine
NCGC00091835-02
NCGC00091835-03
NCGC00091835-04
NCGC00091835-05
NCI60_041682
NINDS_000759
NSC762
Nitol (*Hydrochloride*)
Nitrogen mustard
Nitrogen mustard (HN-2)
Nitrogranulogen
SPBio_000496
SPECTRUM1500375
Spectrum2_000448
Spectrum3_000484
Spectrum4_000924
Spectrum5_001702
Spectrum_000889
Stickstofflost (*Hydrochloride*)
Stickstofflost (ebewe)
T 1024
T-1024
TL 146
UNII-50D9XSG0VR
Valchlor
beta,Beta'-dichlorodiethyl-N-methylamine
beta,beta'-Dichlorodiethyl-N-methylamine
mechlorethamine
thyldiethylamine
β,β'-dichlorodiethyl-N-methylamine
2
Cyclophosphamideapproved, investigationalPhase 2, Phase 3252550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
3
IfosfamideapprovedPhase 2, Phase 33583778-73-23690
Synonyms:
(+-)-Ifosfamid
(+-)-Ifosphamide
(+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
(D,L)-Ifosfamide
(R,S)-Ifosphamide
(R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd
2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis( 2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI)
2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
3,} 2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2- oxide
3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
36341-88-5
3778-73-2
84711-20-6
A 4942
AB00513932
AC-2113
AC1L1GHW
ASTA Z 4942
Ambap3778-73-2
Asta Z 4942
BPBio1_000865
BRN 0611835
BSPBio_000785
C07047
CAS-3778-73-2
CCRIS 352
CHEBI:5864
CHEMBL1024
CID3690
Cyfos
D00343
D007069
DB01181
EINECS 223-237-3
HMS1570H07
HMS2090M12
HMS2093N07
HSDB 7023
Holoxan
Holoxan 1000
I-Phosphamide
I06-0494
IFEX (TN)
Ifex
Ifosfamid
Ifosfamida
Ifosfamida [INN-Spanish]
Ifosfamide
 
Ifosfamide (JAN/USP/INN)
Ifosfamide Sterile
Ifosfamide [USAN:INN:BAN:JAN]
Ifosfamidum
Ifosfamidum [INN-Latin]
Ifosphamide
Ifsofamide
Iphosphamid
Iphosphamid(e)
Iphosphamide
Iso Endoxan
Iso-Endoxan
Isoendoxan
Isofosfamide
Isophosphamide
Isosfamide
LS-102
LS-99799
MJF 9325
MJF-9325
MLS002154021
Mitoxana
Mitoxana, Ifex, Ifosfamide
MolPort-003-666-704
N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid
N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide
N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine
NCGC00016639-01
NCGC00179435-01
NCI-C01638
NCI60_000233
NPFAPI-04
NSC 109,724
NSC 109724
NSC-109,724
NSC-109724
NSC109,724
NSC109724
Naxamide
Prestwick0_000833
Prestwick1_000833
Prestwick2_000833
Prestwick3_000833
S1302_Selleck
SMR001233348
SPBio_002706
STL058690
UNII-UM20QQM95Y
WLN: T6NPOTJ AM2G BO B2G
Z 4942
Z-4942
Z4942
ifosfamide
isosfamide
{3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,
4
Doxorubicinapproved, investigationalPhase 2, Phase 3152523214-92-831703
Synonyms:
(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
(8S-cis)-10-((3-amino-2,3,6-Trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
111266-55-8
14-Hydroxydaunomycin
14-Hydroxydaunorubicine
14-hydroxydaunomycin
14-hydroxydaunorubicine
23214-92-8
23257-17-2
24385-08-8
25311-50-6
25316-40-9
25316-40-9 (hydrochloride)
29042-30-6
AC1L1M5T
AC1Q29OJ
ADM
ADR
Adriablastin
Adriacin (hydrochloride salt)
Adriamycin
Adriamycin PFS
Adriamycin PFS (hydrochloride salt)
Adriamycin RDF
Adriamycin RDF (hydrochloride salt)
Adriamycin Semiquinone
Adriamycin semiquinone
Adriblas tina
Adriblastin
Adriblastina
Adriblastina (TN)
Adriblastina (hydrochloride salt)
Aerosolized Doxorubicin
BPBio1_000502
BRD-K92093830-003-04-3
BSPBio_000456
BSPBio_001031
C01661
C27H29NO11
CCRIS 739
CHEBI:28748
CHEMBL179
CID31703
Caelyx
Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74
Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120
D03899
DB00997
DM2
DOX-SL
Doxil
Doxo
Doxorubicin
Doxorubicin (USAN/INN)
Doxorubicin HCl
 
Doxorubicin Hydrochloride
Doxorubicin [USAN:INN:BAN]
Doxorubicin citrate
Doxorubicin hydrochloride (hydrochloride salt)
Doxorubicin-P4/D10
Doxorubicin-P4/D10 conjugate
Doxorubicin-hLL1
Doxorubicin-hLL1 conjugate
Doxorubicina
Doxorubicina [INN-Spanish]
Doxorubicine
Doxorubicine [INN-French]
Doxorubicinum
Doxorubicinum [INN-Latin]
EINECS 245-495-6
FI 106
Farmablastina (hydrochloride salt)
HMS2089H06
HSDB 3070
Hydroxydaunomycin hydrochlor ide (hydrochloride salt)
Hydroxydaunomycin hydrochloride (hydrochloride salt)
Hydroxydaunorubicin
Hydroxydaunorubicin hydrochloride (hydrochloride salt)
JT9100000
LMPK13050001
LS-1029
LS-165655
MLS000759533
Myocet
NCI-C01514
NChemBio.2007.10-comp13
NDC 38242-874
NIOSH/JT9100000
NSC 123127
Prestwick0_000438
Prestwick1_000438
Prestwick2_000438
Prestwick3_000438
Probes1_000151
Probes2_000129
RDF Rubex
Resmycin
Rubex
Rubex (hydrochloride salt)
SMP1_000106
SPBio_002395
TLC D-99
ThermoDox
Triferric doxorubicin
UNII-80168379AG
adiblastine (hydrochloride salt)
adr iablatina (hydrochloride salt)
adriablastine (hydrochloride salt)
adriablatina (hydrochloride salt)
adriblatina (hydrochloride salt)
doxorubicin
nchembio809-comp5
5
DoxilApproved June 1999Phase 2, Phase 3152531703
Synonyms:
Dox-SL
Doxil
 
Evacet
LipoDox
Pegylated Liposomal Doxorubicin Hydrochloride
liposomal doxorubicin
6Isophosphamide mustardPhase 2, Phase 3358
7
CrizotinibapprovedPhase 279877399-52-511626560, 10366136, 10366137, 10366138, 10366139, 10366140, 10366141
Synonyms:
(R)-Crizotinib
C-Met/HGFR Tyrosine Kinase Inhibitor PF-02341066
C-Met/Hepatocyte Growth Factor Receptor Tyrosine Kinase Inhibitor PF-02341066
Crizotinib
Crizotinibum
 
MET Tyrosine Kinase Inhibitor PF-02341066
PF 2341066
PF-02341066
PF-2341066
Xalkori
crizotinib
8
CeritinibapprovedPhase 1321032900-25-6
Synonyms:
 
N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane-2-sulfonamide
céritinib

Interventional clinical trials:

idNameStatusNCT IDPhase
1Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by SurgeryRecruitingNCT02180867Phase 2, Phase 3
2CREATE: Cross-tumoral Phase 2 With CrizotinibRecruitingNCT01524926Phase 2
3Phase 1/2 Study of X-396, an Oral ALK Inhibitor, in Patients With ALK-positive Non-Small Cell Lung CancerRecruitingNCT01625234Phase 1, Phase 2
4Phase 2 Study Assessing Efficacy and Safety of Crizotinib in Patients Harboring an Alteration on ALK, MET or ROS1RecruitingNCT02034981Phase 2
5A Phase 1/2 Study of the Oral ALK/EGFR Inhibitor AP26113Active, not recruitingNCT01449461Phase 1, Phase 2
6Phase I Study of LDK378 in Pediatric, Malignancies With a Genetic Alteration in Anaplastic Lymphoma Kinase (ALK)RecruitingNCT01742286Phase 1
7Cohort Study of IgG4RDRecruitingNCT01670695Phase 0

Search NIH Clinical Center for Inflammatory Myofibroblastic Tumor

Genetic Tests for Inflammatory Myofibroblastic Tumor

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Anatomical Context for Inflammatory Myofibroblastic Tumor

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MalaCards organs/tissues related to Inflammatory Myofibroblastic Tumor:

33
Lung, Eye, Bone, Liver, Trachea, Heart, Spleen

Animal Models for Inflammatory Myofibroblastic Tumor or affiliated genes

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MGI Mouse Phenotypes related to Inflammatory Myofibroblastic Tumor:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.9CCND1, KIT, MDM2, NPM1, RANBP2, TP53
2MP:00053698.0ACTC1, ACVRL1, DES, KIT, MDM2, TP53
3MP:00053857.5ACTC1, ACVRL1, CCND1, DES, KIT, MDM2
4MP:00107686.7ACTC1, ACVRL1, CCND1, CR2, DES, KIT

Publications for Inflammatory Myofibroblastic Tumor

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Articles related to Inflammatory Myofibroblastic Tumor:

(show top 50)    (show all 478)
idTitleAuthorsYear
1
Inflammatory Myofibroblastic Tumor of the Placenta: A Report of a Novel Lesion in 2 Patients. (26262452)
2015
2
Inflammatory myofibroblastic tumor as a second neoplasm after Wilms tumor. (25504840)
2015
3
Inflammatory myofibroblastic tumor: Clinical, morphological, immunohistochemical and molecular features of a pediatric case. (25149504)
2014
4
Inflammatory Myofibroblastic Tumor of the Urinary Bladder: The Role of IgG4 and the Comparison of Two Immunohistochemical Antibodies and Fluorescence in Situ Hybridization for the Detection of ALK Alterations. (25406945)
2014
5
Inflammatory myofibroblastic tumor of the upper alveolus: A rare entity presenting as a jaw swelling. (25593882)
2014
6
Recurrent inflammatory myofibroblastic tumors harboring PIK3CA and KIT mutations. (25120743)
2014
7
Malignant inflammatory myofibroblastic tumor of the prostate. (23401456)
2013
8
Primary inflammatory myofibroblastic tumor of the stomach in an adult woman: a case report and review of the literature. (23374227)
2013
9
Inflammatory myofibroblastic tumor of the kidney with viral hepatitis B and trauma: A case report. (24273608)
2013
10
Successful Sleeve Lobectomy of Inflammatory Myofibroblastic Tumor in a 4-year-old Child. (23445794)
2013
11
Inflammatory myofibroblastic tumor of the temporal bone presenting with pulsatile tinnitus: a case report. (23787119)
2013
12
A case of recurrent pulmonary inflammatory myofibroblastic tumor with aggressive metastasis after complete resection. (24265646)
2013
13
Fusion of dynactin 1 to anaplastic lymphoma kinase in inflammatory myofibroblastic tumor. (22658521)
2012
14
Inflammatory myofibroblastic tumor of the stomach in an adult female--report of a rare case and review of the literature. (22965515)
2012
15
Regression of an inflammatory myofibroblastic tumor of the porta-hepatis with steroid drugs. (22693097)
2012
16
Rare gastric inflammatory myofibroblastic tumor in an adult woman: a case report with review of the literature. (22570660)
2012
17
Carboplatin plus paclitaxel in the successful treatment of advanced inflammatory myofibroblastic tumor. (22975556)
2012
18
Invasive inflammatory myofibroblastic tumor of the spleen treated with partial splenectomy in a child. (22469943)
2012
19
Inflammatory myofibroblastic tumor of the skin grossly mimicking squamous cell carcinoma: a case report. (21545500)
2012
20
Bilateral simultaneous inflammatory myofibroblastic tumor of the lung with distant metastatic spread. (21606052)
2011
21
Pulmonary inflammatory myofibroblastic tumor expressing a novel fusion, PPFIBP1-ALK: reappraisal of anti-ALK immunohistochemistry as a tool for novel ALK fusion identification. (21430068)
2011
22
Rubbery palatal mass. Inflammatory myofibroblastic tumor. (21903528)
2011
23
Multiorgan involvement in HHV-8-positive multifocal inflammatory myofibroblastic tumor. (21796573)
2011
24
Abdominal inflammatory myofibroblastic tumor: report on four cases and review of literature. (23056847)
2011
25
Pulmonary inflammatory myofibroblastic tumor invading the gastroesophageal junction. (20417808)
2010
26
Inflammatory myofibroblastic tumor of the esophagus. (20103355)
2010
27
Inflammatory myofibroblastic tumor presenting as an abdominal wall mass in an adult patient. (20622374)
2010
28
Inflammatory myofibroblastic tumor of the infratemporal fossa. (20551572)
2010
29
Clinicopathologic study of sinonasal inflammatory myofibroblastic tumor]. (20450762)
2010
30
Asymptomatic inflammatory myofibroblastic tumor of the heart: immunohistochemical profile, differential diagnosis, and review of the literature. (18436455)
2009
31
Inflammatory myofibroblastic tumor in the larynx. (18852998)
2008
32
An inflammatory myofibroblastic tumor in liver with ALK and RANBP2 gene rearrangement: combination of distinct morphologic, immunohistochemical, and genetic features. (18701132)
2008
33
Case report: inflammatory myofibroblastic tumor of the duodenum. (19142589)
2008
34
Renal inflammatory myofibroblastic tumor: a rare tumor indistinguishable from renal cell carcinomaa89report of two cases. (17963086)
2007
35
Inflammatory myofibroblastic tumor of the midesophagus. (18363157)
2007
36
Primary renal inflammatory myofibroblastic tumor. (16401931)
2006
37
Inflammatory myofibroblastic tumor of the renal pelvis]. (16479987)
2006
38
A case of inflammatory myofibroblastic tumor of the urinary bladder finally diagnosed by anaplastic lymphoma kinase (ALK) immunostaining]. (16758729)
2006
39
Inflammatory myofibroblastic tumor of the liver. (17090200)
2006
40
Small bowel intussusception by local recurrence of an inflammatory myofibroblastic tumor: report of a case and review of the literature. (17008862)
2006
41
Inflammatory myofibroblastic tumor (inflammatory pseudotumor) of the breast. (15676017)
2005
42
Inflammatory myofibroblastic tumor associated with renal cell carcinoma. (16230166)
2005
43
Inflammatory myofibroblastic tumor presenting as a pancreatic mass: a case report and review of the literature. (15365204)
2004
44
Identification of CARS-ALK fusion in primary and metastatic lesions of an inflammatory myofibroblastic tumor. (13679433)
2003
45
Inflammatory myofibroblastic tumor of the left ventricle in an older adult. (12822653)
2003
46
Expression of ALK1 and p80 in inflammatory myofibroblastic tumor and its mesenchymal mimics: a study of 135 cases. (12218210)
2002
47
Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor. (11485898)
2001
48
Anaplastic lymphoma kinase (ALK) expression in the inflammatory myofibroblastic tumor: a comparative immunohistochemical study. (11684952)
2001
49
Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. (10383129)
1999
50
Renal failure resulting from infiltration by inflammatory myofibroblastic tumor responsive to corticosteroid therapy. (10074585)
1998

Variations for Inflammatory Myofibroblastic Tumor

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Expression for genes affiliated with Inflammatory Myofibroblastic Tumor

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Search GEO for disease gene expression data for Inflammatory Myofibroblastic Tumor.

Pathways for genes affiliated with Inflammatory Myofibroblastic Tumor

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GO Terms for genes affiliated with Inflammatory Myofibroblastic Tumor

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Cellular components related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle thin filament tropomyosinGO:000586210.8TPM3, TPM4
2focal adhesionGO:00059259.6ACTC1, CLTC, NPM1, TPM4, VIM
3cytosolGO:00058296.8ACTC1, CARS, CCND1, CLTC, DES, MDM2
4cytoplasmGO:00057376.5ACTC1, CARS, CCND1, CLTC, DES, KIT

Biological processes related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1complement receptor mediated signaling pathwayGO:000243010.2CR1, CR2
2movement of cell or subcellular componentGO:00069289.7TPM3, TPM4, VIM
3mitotic G1 DNA damage checkpointGO:00315719.5CCND1, TP53
4muscle filament slidingGO:00300499.1ACTC1, DES, TPM3, TPM4, VIM
5positive regulation of cell proliferationGO:00082848.8CCND1, KIT, MDM2, NPM1, S100B

Molecular functions related to Inflammatory Myofibroblastic Tumor according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein kinase bindingGO:00199019.5ACVRL1, CCND1, CLTC, NPM1, TP53
2identical protein bindingGO:00428028.8ALK, DES, MDM2, S100B, TP53, VIM
3protein bindingGO:00055155.3ACTC1, ACVRL1, ALK, CARS, CCND1, CLTC

Sources for Inflammatory Myofibroblastic Tumor

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet